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Aliases for NPIPB3 Gene

Aliases for NPIPB3 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B3 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B3 2 3
  • Nuclear Pore Complex-Interacting Protein-Like 3 3 4
  • Protein Pps22-1 3 4
  • NPIPL3 3 4
  • PI-3-Kinase-Related Kinase SMG-1 Isoform 1 Homolog 3
  • Nuclear Pore Complex Interacting Protein-Like 3 2
  • Nuclear Pore Complex-Interacting Protein B Type 3
  • KIAA0220-Like Protein 3
  • KIAA0220L 3
  • KIAA0220 4
  • NPIPB5 3
  • NPIPB 3
  • NPIP 3

External Ids for NPIPB3 Gene

Previous HGNC Symbols for NPIPB3 Gene

  • NPIPL3

Summaries for NPIPB3 Gene

GeneCards Summary for NPIPB3 Gene

NPIPB3 (Nuclear Pore Complex Interacting Protein Family Member B3) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB3 Gene

Genomics for NPIPB3 Gene

Regulatory Elements for NPIPB3 Gene

Enhancers for NPIPB3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around NPIPB3 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB3 Gene

21,402,134 bp from pter
21,448,567 bp from pter
46,434 bases
Minus strand

Genomic View for NPIPB3 Gene

Genes around NPIPB3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB3 Gene

Proteins for NPIPB3 Gene

  • Protein details for NPIPB3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B3
    Protein Accession:
    Secondary Accessions:
    • O43332
    • Q504Q6
    • Q59F29
    • Q6GMR1
    • Q6P7T2
    • Q6PIE2
    • Q6RH21

    Protein attributes for NPIPB3 Gene

    1050 amino acids
    Molecular mass:
    116847 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA13210.2; Type=Frameshift; Positions=203; Evidence={ECO:0000305}; Sequence=BAD92869.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for NPIPB3 Gene

neXtProt entry for NPIPB3 Gene

Proteomics data for NPIPB3 Gene at MOPED

Post-translational modifications for NPIPB3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NPIPB3 Gene

No data available for DME Specific Peptides for NPIPB3 Gene

Domains & Families for NPIPB3 Gene

Protein Domains for NPIPB3 Gene


Suggested Antigen Peptide Sequences for NPIPB3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB3: view

No data available for Gene Families for NPIPB3 Gene

Function for NPIPB3 Gene

Phenotypes for NPIPB3 Gene

GenomeRNAi human phenotypes for NPIPB3:
genes like me logo Genes that share phenotypes with NPIPB3: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB3 Gene

Localization for NPIPB3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB3 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NPIPB3 Gene

Pathways & Interactions for NPIPB3 Gene

SuperPathways for NPIPB3 Gene

No Data Available

Interacting Proteins for NPIPB3 Gene

Gene Ontology (GO) - Biological Process for NPIPB3 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB3 Gene

Drugs & Compounds for NPIPB3 Gene

No Compound Related Data Available

Transcripts for NPIPB3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB3 Gene

No ASD Table

Relevant External Links for NPIPB3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB3 Gene

mRNA expression in normal human tissues for NPIPB3 Gene

Protein differential expression in normal tissues from HIPED for NPIPB3 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NPIPB3 Gene

genes like me logo Genes that share expression patterns with NPIPB3: view

Protein tissue co-expression partners for NPIPB3 Gene

- Elite partner

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NPIPB3 Gene

Orthologs for NPIPB3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC750787 35
  • 89.91 (n)
  • 82.24 (a)
-- 36
  • 36 (a)
-- 36
  • 42 (a)
Species with no ortholog for NPIPB3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB3 Gene

Gene Tree for NPIPB3 (if available)
Gene Tree for NPIPB3 (if available)

Paralogs for NPIPB3 Gene

genes like me logo Genes that share paralogs with NPIPB3: view

Variants for NPIPB3 Gene

Sequence variations from dbSNP and Humsavar for NPIPB3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs62047567 -- 21,425,967(+) CTGCT(A/G)CATCT upstream-variant-2KB

Variation tolerance for NPIPB3 Gene

Gene Damage Index Score: 0.06; 1.28% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for NPIPB3 Gene

Disorders for NPIPB3 Gene

Relevant External Links for NPIPB3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NPIPB3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB3 Gene

Publications for NPIPB3 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4 67
  2. Divergent origins and concerted expansion of two segmental duplications on chromosome 16. (PMID: 11948212) Eichler E.E. … Rocchi M. (J. Hered. 2001) 2 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for NPIPB3 Gene

Sources for NPIPB3 Gene