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Aliases for NPIPB3 Gene

Aliases for NPIPB3 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B3 2 3
  • Nuclear Pore Complex-Interacting Protein-Like 3 3 4
  • Protein Pps22-1 3 4
  • NPIPL3 3 4
  • PI-3-Kinase-Related Kinase SMG-1 Isoform 1 Homolog 3
  • Nuclear Pore Complex Interacting Protein-Like 3 2
  • Nuclear Pore Complex-Interacting Protein B Type 3
  • KIAA0220-Like Protein 3
  • KIAA0220L 3
  • KIAA0220 4
  • NPIPB5 3
  • NPIPB 3
  • NPIP 3

External Ids for NPIPB3 Gene

Previous HGNC Symbols for NPIPB3 Gene

  • NPIPL3

Summaries for NPIPB3 Gene

GeneCards Summary for NPIPB3 Gene

NPIPB3 (Nuclear Pore Complex Interacting Protein Family, Member B3) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB3 Gene

Genomics for NPIPB3 Gene

Genomic Location for NPIPB3 Gene

Start:
21,402,134 bp from pter
End:
21,448,567 bp from pter
Size:
46,434 bases
Orientation:
Minus strand

Genomic View for NPIPB3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NPIPB3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB3 Gene

No data available for Regulatory Elements for NPIPB3 Gene

Proteins for NPIPB3 Gene

  • Protein details for NPIPB3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q92617-NPIB3_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B3
    Protein Accession:
    Q92617
    Secondary Accessions:
    • O43332
    • Q504Q6
    • Q59F29
    • Q6GMR1
    • Q6P7T2
    • Q6PIE2
    • Q6RH21

    Protein attributes for NPIPB3 Gene

    Size:
    1050 amino acids
    Molecular mass:
    116847 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA13210.2; Type=Frameshift; Positions=203; Evidence={ECO:0000305}; Sequence=BAD92869.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for NPIPB3 Gene

neXtProt entry for NPIPB3 Gene

Proteomics data for NPIPB3 Gene at MOPED

Post-translational modifications for NPIPB3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NPIPB3 Gene

No data available for DME Specific Peptides for NPIPB3 Gene

Domains for NPIPB3 Gene

Protein Domains for NPIPB3 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q92617

UniProtKB/Swiss-Prot:

NPIB3_HUMAN :
  • Q92617
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB3: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPB3 Gene

Function for NPIPB3 Gene

Gene Ontology (GO) - Molecular Function for NPIPB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with NPIPB3: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NPIPB3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NPIPB3 Gene

Localization for NPIPB3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB3 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for NPIPB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB3: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB3 Gene

Pathways for NPIPB3 Gene

SuperPathways for NPIPB3 Gene

No Data Available

Interacting Proteins for NPIPB3 Gene

Gene Ontology (GO) - Biological Process for NPIPB3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with NPIPB3: view

No data available for Pathways by source for NPIPB3 Gene

Transcripts for NPIPB3 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NPIPB3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB3 Gene

No ASD Table

Relevant External Links for NPIPB3 Gene

GeneLoc Exon Structure for
NPIPB3
ECgene alternative splicing isoforms for
NPIPB3

Expression for NPIPB3 Gene

mRNA expression in normal human tissues for NPIPB3 Gene

Protein differential expression in normal tissues for NPIPB3 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for NPIPB3 Gene

genes like me logo Genes that share expressions with NPIPB3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NPIPB3 Gene

Orthologs for NPIPB3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750787 35
  • 89.91 (n)
  • 82.24 (a)
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
Species with no ortholog for NPIPB3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB3 Gene

ENSEMBL:
Gene Tree for NPIPB3 (if available)
TreeFam:
Gene Tree for NPIPB3 (if available)

Paralogs for NPIPB3 Gene

genes like me logo Genes that share paralogs with NPIPB3: view

Variants for NPIPB3 Gene

Sequence variations from dbSNP and Humsavar for NPIPB3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs438495 -- 21,404,210(-) CCTGC(C/T)GAGCG reference, synonymous-codon
rs678966 -- 21,404,378(+) AAGGG(C/G)AGTGA missense, reference
rs28478606 -- 21,412,036(+) GAGGC(C/T)GAGGC intron-variant
rs28496884 -- 21,412,310(+) TCACA(C/T)AACTG intron-variant
rs28505816 -- 21,411,995(+) GCCAG(A/G)TGCGG intron-variant

Relevant External Links for NPIPB3 Gene

HapMap Linkage Disequilibrium report
NPIPB3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB3 Gene

Disorders for NPIPB3 Gene

No disorders were found for NPIPB3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NPIPB3 Gene

Publications for NPIPB3 Gene

  1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T. … Nomura N. (DNA Res. 1996) 3 4
  2. Divergent origins and concerted expansion of two segmental duplications on chromosome 16. (PMID: 11948212) Eichler E.E. … Rocchi M. (J. Hered. 2001) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4
  5. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3

Products for NPIPB3 Gene

Sources for NPIPB3 Gene

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