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Aliases for NPIPB11 Gene

Aliases for NPIPB11 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B11 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B11 2
  • Nuclear Pore Complex-Interacting Protein Family Member B11 3
  • Hepatitis B Virus Pre-Pre-S Promoter DNA-Binding Protein 3
  • NPIP-Like Locus 3
  • Pps22-1 Protein 3
  • NPIP 3

External Ids for NPIPB11 Gene

Summaries for NPIPB11 Gene

GeneCards Summary for NPIPB11 Gene

NPIPB11 (Nuclear Pore Complex Interacting Protein Family Member B11) is a Protein Coding gene. An important paralog of this gene is NPIPB5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB11 Gene

Genomics for NPIPB11 Gene

Regulatory Elements for NPIPB11 Gene

Enhancers for NPIPB11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F029972 1.1 ENCODE 17.9 -569.9 -569879 6.1 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 NPIPB13 ZNF747 ZNF764 INO80E ENSG00000260367 ZNF785 SMG1P2 BCL7C NPIPB11 CDIPT
GH16F029271 1.5 FANTOM5 Ensembl ENCODE 9.9 +133.1 133078 3.2 HDGF PKNOX1 SIN3A YBX1 ZNF48 ZNF207 FOS SP3 ZNF264 MEF2D ENSG00000260853 MIR4517 SMG1P2 ENSG00000260367 SGF29 NPIPB13 CDIPT ENSG00000260953 ENSG00000261766 NPIPB11
GH16F029258 1.3 FANTOM5 Ensembl ENCODE 9.9 +141.1 141051 11.3 HDGF PKNOX1 ARNT MLX ARID4B SIN3A YBX1 FOS SP3 MXD4 ENSG00000260853 MIR4517 SMG1P2 ENSG00000260367 SGF29 NPIPB13 CDIPT ENSG00000260953 ENSG00000261766 NPIPB11
GH16F029686 1 Ensembl ENCODE 9.8 -282.8 -282769 3.3 ATF1 ARNT SIN3A ARID4B ZNF2 GATA2 CBX5 ZNF143 DEK PAF1 NPIPB13 NPIPB11 ENSG00000260853 ENSG00000235560 RN7SKP127 KIF22 GDPD3 ENSG00000251417 GC16P029695 QPRT
GH16F029700 1.1 FANTOM5 Ensembl ENCODE 9.8 -296.2 -296247 3.6 SIN3A ARID4B CBX5 ZNF143 DEK REST TBX21 MIER3 PBX2 NBN NPIPB13 C16orf54 MVP DOC2A NPIPB11 ENSG00000260853 ENSG00000235560 RN7SKP127 CORO1A HIRIP3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around NPIPB11 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB11 Gene

29,381,183 bp from pter
29,405,678 bp from pter
24,496 bases
Minus strand

Genomic View for NPIPB11 Gene

Genes around NPIPB11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB11 Gene

Proteins for NPIPB11 Gene

  • Protein details for NPIPB11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B11
    Protein Accession:

    Protein attributes for NPIPB11 Gene

    1161 amino acids
    Molecular mass:
    129208 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB11 Gene

Post-translational modifications for NPIPB11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NPIPB11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NPIPB11 Gene

Domains & Families for NPIPB11 Gene

Protein Domains for NPIPB11 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB11: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPB11 Gene

Function for NPIPB11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB11 Gene

Localization for NPIPB11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB11 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for NPIPB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB11: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB11 Gene

Pathways & Interactions for NPIPB11 Gene

SuperPathways for NPIPB11 Gene

No Data Available

Interacting Proteins for NPIPB11 Gene

Gene Ontology (GO) - Biological Process for NPIPB11 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB11 Gene

Transcripts for NPIPB11 Gene

mRNA/cDNA for NPIPB11 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB11 Gene

No ASD Table

Relevant External Links for NPIPB11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB11 Gene

mRNA expression in normal human tissues for NPIPB11 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NPIPB11 Gene

NURSA nuclear receptor signaling pathways regulating expression of NPIPB11 Gene:

genes like me logo Genes that share expression patterns with NPIPB11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for NPIPB11 Gene

Orthologs for NPIPB11 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB11 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC750787 34
  • 91.38 (n)
-- 35
  • 74 (a)
-- 35
  • 73 (a)
Species where no ortholog for NPIPB11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB11 Gene

Gene Tree for NPIPB11 (if available)
Gene Tree for NPIPB11 (if available)

Paralogs for NPIPB11 Gene Pseudogenes for NPIPB11 Gene

genes like me logo Genes that share paralogs with NPIPB11: view

Variants for NPIPB11 Gene

Sequence variations from dbSNP and Humsavar for NPIPB11 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs111306101 -- 29,397,795(+) AGGGG(A/G)GAAGT intron-variant
rs111574103 -- 29,389,226(+) CAAAT(-/GTG)GTGGC intron-variant
rs112123231 -- 29,387,915(+) ACCAC(A/G)AGGCA intron-variant
rs112165220 -- 29,397,634(+) CACCG(C/T)CCCCG intron-variant
rs112373333 -- 29,395,390(+) CTCGT(G/T)ACCTC intron-variant

Variation tolerance for NPIPB11 Gene

Gene Damage Index Score: 3.08; 50.81% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB11 Gene

Disorders for NPIPB11 Gene

Relevant External Links for NPIPB11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NPIPB11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB11 Gene

Publications for NPIPB11 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4 64

Products for NPIPB11 Gene

Sources for NPIPB11 Gene

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