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Aliases for NPIPB11 Gene

Aliases for NPIPB11 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B11 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B11 2
  • Nuclear Pore Complex-Interacting Protein Family Member B11 3
  • Hepatitis B Virus Pre-Pre-S Promoter DNA-Binding Protein 3
  • NPIP-Like Locus 3
  • Pps22-1 Protein 3
  • NPIP 3

External Ids for NPIPB11 Gene

Summaries for NPIPB11 Gene

GeneCards Summary for NPIPB11 Gene

NPIPB11 (Nuclear Pore Complex Interacting Protein Family Member B11) is a Protein Coding gene. An important paralog of this gene is NPIPB4.

Additional gene information for NPIPB11 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB11 Gene

Genomics for NPIPB11 Gene

Regulatory Elements for NPIPB11 Gene

Enhancers for NPIPB11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H028821 1.4 ENCODE dbSUPER 19.3 +581.5 581547 4 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D SSRP1 TUFM NPIPB12 ENSG00000198106 SH2B1 ATXN2L NPIPB11 ENSG00000260853 CA5AP1 ENSG00000251417 SPNS1
GH16H029972 1.4 Ensembl ENCODE 17.9 -569.9 -569879 6 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 SETD1A INO80E NPIPB12 NPIPB13 SRCAP ZNF785 BCL7C ZNF747 ENSG00000198106 ZNF764
GH16H029273 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.9 +131.8 131778 0 HDGF PKNOX1 FOXA2 ARNT YBX1 ZBTB7B TCF12 ZNF207 FOS ATF7 NPIPB12 ENSG00000260853 ATXN2L INO80E NPIPB13 SPNS1 ENSG00000261766 ENSG00000260796 NFATC2IP ENSG00000198106
GH16H029803 1.5 ENCODE dbSUPER 11.3 -402.8 -402766 10 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 SP3 ZNF785 SH2B1 SRCAP ATXN2L NPIPB12 ZNF764 INO80E RNF40 ENSG00000260853 SPNS1
GH16H030063 1.4 ENCODE dbSUPER 11.3 -659.9 -659942 4 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A YPEL3 SETD1A RNF40 SMG1P5 ZNF747 SMG1P2 INO80E SRCAP CA5AP1 LOC647086
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NPIPB11 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB11 Gene

29,381,183 bp from pter
29,405,678 bp from pter
24,496 bases
Minus strand

Genomic View for NPIPB11 Gene

Genes around NPIPB11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB11 Gene

Proteins for NPIPB11 Gene

  • Protein details for NPIPB11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B11
    Protein Accession:

    Protein attributes for NPIPB11 Gene

    1161 amino acids
    Molecular mass:
    129208 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB11 Gene

Post-translational modifications for NPIPB11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NPIPB11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NPIPB11 Gene

Domains & Families for NPIPB11 Gene

Gene Families for NPIPB11 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for NPIPB11 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB11: view

No data available for Suggested Antigen Peptide Sequences for NPIPB11 Gene

Function for NPIPB11 Gene

Phenotypes From GWAS Catalog for NPIPB11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB11 Gene

Localization for NPIPB11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB11 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB11: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB11 Gene

Pathways & Interactions for NPIPB11 Gene

SuperPathways for NPIPB11 Gene

No Data Available

Interacting Proteins for NPIPB11 Gene

Gene Ontology (GO) - Biological Process for NPIPB11 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB11 Gene

Drugs & Compounds for NPIPB11 Gene

No Compound Related Data Available

Transcripts for NPIPB11 Gene

mRNA/cDNA for NPIPB11 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB11 Gene

No ASD Table

Relevant External Links for NPIPB11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NPIPB11 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NPIPB11 Gene

NURSA nuclear receptor signaling pathways regulating expression of NPIPB11 Gene:

genes like me logo Genes that share expression patterns with NPIPB11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB11 Gene

Orthologs for NPIPB11 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB11 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC750787 33
  • 91.38 (n)
-- 34
  • 74 (a)
-- 34
  • 73 (a)
Species where no ortholog for NPIPB11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB11 Gene

Gene Tree for NPIPB11 (if available)
Gene Tree for NPIPB11 (if available)

Paralogs for NPIPB11 Gene Pseudogenes for NPIPB11 Gene

genes like me logo Genes that share paralogs with NPIPB11: view

Variants for NPIPB11 Gene

Sequence variations from dbSNP and Humsavar for NPIPB11 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000106608 -- 29,401,726(+) GGCAA(C/G)AGTTG intron-variant
rs1000389092 -- 29,397,162(+) TGAGA(-/CT)CTGTC intron-variant
rs1000672527 -- 29,383,214(+) AGGGT(A/G)GAGCT reference, missense
rs1000844812 -- 29,392,544(+) GACTC(G/T)ACTAA intron-variant
rs1000875660 -- 29,392,350(+) GGTGC(A/G)AAGTT intron-variant

Variation tolerance for NPIPB11 Gene

Gene Damage Index Score: 3.08; 50.81% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB11 Gene

Disorders for NPIPB11 Gene

Relevant External Links for NPIPB11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NPIPB11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB11 Gene

Publications for NPIPB11 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 60

Products for NPIPB11 Gene

Sources for NPIPB11 Gene

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