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Aliases for NPIPA8 Gene

Aliases for NPIPA8 Gene

  • Nuclear Pore Complex Interacting Protein Family Member A8 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member A8 2 3
  • Morpheus Gene Family Member 9 2 3
  • LCR16a9 3

External Ids for NPIPA8 Gene

Previous GeneCards Identifiers for NPIPA8 Gene

  • GC16P016420
  • GC16M018413

Summaries for NPIPA8 Gene

GeneCards Summary for NPIPA8 Gene

NPIPA8 (Nuclear Pore Complex Interacting Protein Family Member A8) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPA8 Gene

Genomics for NPIPA8 Gene

Genomic Location for NPIPA8 Gene

18,317,919 bp from pter
18,336,736 bp from pter
18,818 bases
Minus strand

Genomic View for NPIPA8 Gene

Genes around NPIPA8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPA8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPA8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPA8 Gene

No data available for Regulatory Elements for NPIPA8 Gene

Proteins for NPIPA8 Gene

  • Protein details for NPIPA8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member A8
    Protein Accession:

    Protein attributes for NPIPA8 Gene

    369 amino acids
    Molecular mass:
    42230 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPA8 Gene

Proteomics data for NPIPA8 Gene at MOPED

Post-translational modifications for NPIPA8 Gene

No Post-translational modifications

Other Protein References for NPIPA8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NPIPA8 Gene

Domains & Families for NPIPA8 Gene

Protein Domains for NPIPA8 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPA8: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPA8 Gene

Function for NPIPA8 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPA8 Gene

Localization for NPIPA8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NPIPA8 Gene

Pathways & Interactions for NPIPA8 Gene

SuperPathways for NPIPA8 Gene

No Data Available

Interacting Proteins for NPIPA8 Gene

Gene Ontology (GO) - Biological Process for NPIPA8 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPA8 Gene

Drugs & Compounds for NPIPA8 Gene

No Compound Related Data Available

Transcripts for NPIPA8 Gene

mRNA/cDNA for NPIPA8 Gene

(5) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPA8 Gene

No ASD Table

Relevant External Links for NPIPA8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPA8 Gene

mRNA expression in normal human tissues for NPIPA8 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPA8 Gene

This gene is overexpressed in Brain - Cerebellum (x5.3) and Brain - Cerebellar Hemisphere (x4.1).
genes like me logo Genes that share expression patterns with NPIPA8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NPIPA8 Gene

Orthologs for NPIPA8 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPA8 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 84 (a)
Species with no ortholog for NPIPA8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPA8 Gene

Gene Tree for NPIPA8 (if available)
Gene Tree for NPIPA8 (if available)

Paralogs for NPIPA8 Gene

genes like me logo Genes that share paralogs with NPIPA8: view

Variants for NPIPA8 Gene

Sequence variations from dbSNP and Humsavar for NPIPA8 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs71240157 -- 18,332,619(-) CTGTA(A/C)AACCT upstream-variant-2KB, reference, missense
rs111563943 -- 18,334,941(+) CCGGC(A/C)GGTGT upstream-variant-2KB

Variation tolerance for NPIPA8 Gene

Gene Damage Index Score: 0.24; 5.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPA8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPA8 Gene

Disorders for NPIPA8 Gene

Relevant External Links for NPIPA8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NPIPA8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPA8 Gene

Publications for NPIPA8 Gene

  1. Positive selection of a gene family during the emergence of humans and African apes. (PMID: 11586358) Johnson M.E. … Eichler E.E. (Nature 2001) 2 3 67

Products for NPIPA8 Gene

Sources for NPIPA8 Gene

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