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Aliases for NPIPA7 Gene

Aliases for NPIPA7 Gene

  • Nuclear Pore Complex Interacting Protein Family Member A7 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member A7 2

External Ids for NPIPA7 Gene

Previous GeneCards Identifiers for NPIPA7 Gene

  • GC16P016472

Summaries for NPIPA7 Gene

GeneCards Summary for NPIPA7 Gene

NPIPA7 (Nuclear Pore Complex Interacting Protein Family Member A7) is a Protein Coding gene. An important paralog of this gene is NPIPA8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPA7 Gene

Genomics for NPIPA7 Gene

Regulatory Elements for NPIPA7 Gene

Enhancers for NPIPA7 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around NPIPA7 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPA7 Gene

Chromosome:
16
Start:
16,378,794 bp from pter
End:
16,393,972 bp from pter
Size:
15,179 bases
Orientation:
Plus strand

Genomic View for NPIPA7 Gene

Genes around NPIPA7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPA7 Gene

Proteins for NPIPA7 Gene

  • Protein details for NPIPA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E9PJI5-NPIA7_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member A7
    Protein Accession:
    E9PJI5

    Protein attributes for NPIPA7 Gene

    Size:
    369 amino acids
    Molecular mass:
    42230 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPA7 Gene

Post-translational modifications for NPIPA7 Gene

No Post-translational modifications

Other Protein References for NPIPA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NPIPA7 Gene

Domains & Families for NPIPA7 Gene

Protein Domains for NPIPA7 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

E9PJI5

UniProtKB/Swiss-Prot:

NPIA7_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPA7: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPA7 Gene

Function for NPIPA7 Gene

Gene Ontology (GO) - Molecular Function for NPIPA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NPIPA7: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPA7 Gene

Localization for NPIPA7 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NPIPA7 Gene

Pathways & Interactions for NPIPA7 Gene

SuperPathways for NPIPA7 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NPIPA7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPA7 Gene

Drugs & Compounds for NPIPA7 Gene

No Compound Related Data Available

Transcripts for NPIPA7 Gene

mRNA/cDNA for NPIPA7 Gene

(11) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPA7 Gene

No ASD Table

Relevant External Links for NPIPA7 Gene

GeneLoc Exon Structure for
NPIPA7
ECgene alternative splicing isoforms for
NPIPA7

Expression for NPIPA7 Gene

mRNA expression in normal human tissues for NPIPA7 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPA7 Gene

This gene is overexpressed in Brain - Cerebellum (x4.9).

NURSA nuclear receptor signaling pathways regulating expression of NPIPA7 Gene:

NPIPA7
genes like me logo Genes that share expression patterns with NPIPA7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for NPIPA7 Gene

Orthologs for NPIPA7 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPA7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 84 (a)
OneToMany
Species where no ortholog for NPIPA7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPA7 Gene

ENSEMBL:
Gene Tree for NPIPA7 (if available)
TreeFam:
Gene Tree for NPIPA7 (if available)

Paralogs for NPIPA7 Gene

genes like me logo Genes that share paralogs with NPIPA7: view

Variants for NPIPA7 Gene

Sequence variations from dbSNP and Humsavar for NPIPA7 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs62032900 -- 16,377,312(+) ACCAC(C/G)TGGGA upstream-variant-2KB
rs62032901 -- 16,377,644(+) ATCTC(A/G)GCTCA upstream-variant-2KB
rs62032902 -- 16,379,503(+) GGGAC(C/T)GAGAT intron-variant, upstream-variant-2KB
rs200032220 -- 16,378,748(+) CACAC(A/G)GGCAG upstream-variant-2KB
rs771301598 -- 16,376,976(+) GGCAG(C/T)AGGTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for NPIPA7 Gene

Variant ID Type Subtype PubMed ID
dgv2775n100 CNV gain 25217958
dgv2776n100 CNV gain+loss 25217958
dgv2777n100 CNV loss 25217958
dgv2781n100 CNV gain+loss 25217958
dgv2782n100 CNV loss 25217958
dgv2783n100 CNV gain 25217958
dgv2784n100 CNV gain 25217958
dgv4924n54 CNV gain 21841781
esv2714015 CNV deletion 23290073
esv2751550 CNV gain 17911159
esv2758633 CNV gain+loss 17122850
esv2758634 CNV gain+loss 17122850
esv2762276 CNV gain+loss 21179565
esv28069 CNV gain+loss 19812545
esv28183 CNV gain+loss 19812545
esv33614 CNV gain+loss 17666407
esv3382186 CNV duplication 20981092
esv3392452 CNV duplication 20981092
esv3409391 CNV duplication 20981092
esv34419 CNV gain 17911159
esv3449324 CNV duplication 20981092
esv3570398 CNV gain 25503493
esv3582069 CNV loss 25503493
esv3892799 CNV gain 25118596
nsv1043239 CNV gain 25217958
nsv1047898 CNV loss 25217958
nsv1048002 CNV gain 25217958
nsv1049647 CNV gain+loss 25217958
nsv1115496 CNV duplication 24896259
nsv1124728 CNV duplication 24896259
nsv1125134 CNV deletion 24896259
nsv1139642 CNV duplication 24896259
nsv1139643 CNV duplication 24896259
nsv1147818 CNV duplication 26484159
nsv1151531 CNV duplication 26484159
nsv1160365 CNV duplication 26073780
nsv1746 CNV insertion 18451855
nsv1751 CNV deletion 18451855
nsv428319 CNV loss 18775914
nsv428320 CNV loss 18775914
nsv433436 CNV gain 18776910
nsv435664 CNV deletion 17901297
nsv457428 CNV gain 19166990
nsv509599 CNV insertion 20534489
nsv509601 CNV insertion 20534489
nsv7278 OTHER inversion 18451855
nsv820784 CNV deletion 20802225
nsv820818 CNV deletion 20802225
nsv952939 CNV deletion 24416366
nsv952942 CNV deletion 24416366
nsv974868 CNV duplication 23825009
nsv977920 CNV duplication 23825009
nsv977929 CNV duplication 23825009
nsv978034 CNV duplication 23825009
nsv984384 CNV duplication 23825009

Variation tolerance for NPIPA7 Gene

Gene Damage Index Score: 0.32; 7.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPA7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPA7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NPIPA7 Gene

Disorders for NPIPA7 Gene

Relevant External Links for NPIPA7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NPIPA7

No disorders were found for NPIPA7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPA7 Gene

Publications for NPIPA7 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 65
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 65

Products for NPIPA7 Gene

Sources for NPIPA7 Gene

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