Subcategory (RNA class) for NPHP3-ACAD11 Gene
Quality Score for this RNA gene is
External Ids for NPHP3-ACAD11 Gene
Previous GeneCards Identifiers for NPHP3-ACAD11 Gene
This locus represents naturally occurring read-through transcription between the neighboring NPHP3 (nephronophthisis 3, adolescent) and ACAD11 (acyl-CoA dehydrogenase family, member 11) genes on chromosome 3. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]
GeneCards Summary for NPHP3-ACAD11 Gene
NPHP3-ACAD11 (NPHP3-ACAD11 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Diseases associated with NPHP3-ACAD11 include nephronophthisis 3 and renal-hepatic-pancreatic dysplasia 1.
UniProtKB/Swiss-Prot for NPHP3-ACAD11 Gene
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.