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NPHP3-ACAD11 Gene

protein-coding   GIFtS: 26
GCID: GC03M132278

NPHP3-ACAD11 Readthrough (NMD Candidate)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NPHP3-ACAD11 Readthrough (NMD Candidate)1 2
KIAA20003

External Ids:    HGNC: 483511   Entrez Gene: 1005327242   Ensembl: ENSG000001139717   UniProtKB: Q7Z4943   

Export aliases for NPHP3-ACAD11 gene to outside databases

Previous GC identifer: GC03U901738


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NPHP3-ACAD11 Gene:
This locus represents naturally occurring read-through transcription between the neighboring NPHP3
(nephronophthisis 3, adolescent) and ACAD11 (acyl-CoA dehydrogenase family, member 11) genes on chromosome 3. The
read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a
protein product. (provided by RefSeq, Feb 2011)

GeneCards Summary for NPHP3-ACAD11 Gene:
NPHP3-ACAD11 (NPHP3-ACAD11 readthrough (NMD candidate)) is a protein-coding gene. Diseases associated with NPHP3-ACAD11 include nephronophthisis 3, and renal-hepatic-pancreatic dysplasia. An important paralog of this gene is KLC2.

UniProtKB/Swiss-Prot: NPHP3_HUMAN, Q7Z494
Function: Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical
Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates
planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for
proper convergent extension cell movements




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for NPHP3-ACAD11
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NPHP3-ACAD11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NPHP3-ACAD11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  3q22.1   

NPHP3-ACAD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPHP3-ACAD11 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M132278:  view genomic region     (about GC identifiers)

Start:
132,276,982 bp from pter      End:
132,441,303 bp from pter
Size:
164,322 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for NPHP3-ACAD11

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NPHP3_HUMAN, Q7Z494 (See protein sequence)
Recommended Name: Nephrocystin-3  
Size: 1330 amino acids; 150864 Da
Subunit: Interacts with NPHP1 and INVS/NPHP2. Interacts (when myristoylated) with UNC119 and UNC119B; interaction
is required for localization to cilium. Interacts with CEP164. Component of a complex containing at least ANKS6,
INVS, NEK8 and NPHP3. ANKS6 may organize complex assembly by linking INVS and NPHP3 to NEK8 and INVS may target
the complex to the proximal ciliary axoneme
Sequence caution: Sequence=BAB70891.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC02709.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAC04268.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q5JPE3 Q5JPE6 Q68D99 Q6NVH3 Q7Z492 Q7Z493 Q8N9R2 Q8NCM5 Q96N70 Q96NK2
Alternative splicing: 7 isoforms:  Q7Z494-1   Q7Z494-2   Q7Z494-3   Q7Z494-4   Q7Z494-5   Q7Z494-6   Q7Z494-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NPHP3-ACAD11: NX_Q7Z494

Explore proteomics data for NPHP3-ACAD11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NPHP3-ACAD11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


    ENSEMBL proteins: 
     ENSP00000419763   ENSP00000419907   ENSP00000427666   ENSP00000338766   ENSP00000418664  
     ENSP00000319909   ENSP00000344802   ENSP00000372769  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR027417 P-loop_NTPase
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q7Z494

    ProtoNet protein and cluster: Q7Z494

    UniProtKB/Swiss-Prot: NPHP3_HUMAN, Q7Z494
    Similarity: Contains 11 TPR repeats


    NPHP3-ACAD11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NPHP3_HUMAN, Q7Z494
    Function: Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical
    Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates
    planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for
    proper convergent extension cell movements

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    NPHP3-ACAD11 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NPHP3-ACAD11
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NPHP3_HUMAN, Q7Z494: Cell projection, cilium. Note=Localization to cilium is mediated via interaction with UNC119
    and UNC119B, which bind to the myristoyl moiety of the N-terminus

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005929cilium ----
    GO:0072372primary cilium ----

    NPHP3-ACAD11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NPHP3-ACAD11
    Interactions:

        Search GeneGlobe Interaction Network for NPHP3-ACAD11

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for NPHP3-ACAD11 (Q7Z4941, 2, 3 ENSP000003387664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NPHP1O152593, ENSP000003131694I2D: score=2 STRING: ENSP00000313169
    CEP164Q9UPV01EBI-2804263,EBI-3937015
    UNC119Q134322MINT-8411894
    UNC119BA6NIH72MINT-8411953
    INVSENSP000002624574STRING: ENSP00000262457
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 24):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001822kidney development ----
    GO:0001947heart looping ----
    GO:0003283atrial septum development ----
    GO:0006629lipid metabolic process ----
    GO:0007163establishment or maintenance of cell polarity ----

    NPHP3-ACAD11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NPHP3-ACAD11 (NPHP3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000471702(uc003eoz.1 uc003epf.2) ENST00000474871 ENST00000493732
    ENST00000490993 ENST00000465756 ENST00000512094 ENST00000337331 ENST00000515289
    ENST00000469232 ENST00000476742 ENST00000471145 ENST00000326682(uc003epd.2 uc003epe.2)
    ENST00000343113 ENST00000383282
    miRNA
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    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NPHP3-ACAD11 (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:        -                                                                                         -                                                         
    SP2:                                                                                                                                                            
    SP3:                                                                                            -     -                                                         
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 25a · 25b ^ 26 ^ 27 ^ 28a · 28b · 28c ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35a · 35b ^ 36 ^ 37 ^ 38 ^ 39 ^ 40a · 40b ^ 41 ^ 42a · 42b ^ 43 ^
    SP1:  -                                                                                                                                                         
    SP2:                                                                                                                                                  -     -   
    SP3:  -     -                                                                                                                                                   
    SP4:                                                                                                                                                  -         
    SP5:                                                                                                                                                            

    ExUns: 44 ^ 45 ^ 46 ^ 47 ^ 48 ^ 49
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for NPHP3-ACAD11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    See probesets specificity/sensitivity at GeneAnnot
    CGAP TAG: --

    NPHP3-ACAD11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NPHP3-ACAD11 Protein Expression

    UniProtKB/Swiss-Prot: NPHP3_HUMAN, Q7Z494
    Tissue specificity: Widely expressed at low level. Expressed in heart, placenta, liver, skeletal muscle, kidney
    and pancreas. Expressed at very low level in brain and lung

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPHP3-ACAD11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NPHP3-ACAD11 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NPHP36
    nephronophthisis 3 (adolescent)
    84(a)
    1 ↔ 1
    2(42926896-42952850)
    lizard
    (Anolis carolinensis)
    Reptilia NPHP36
    nephronophthisis 3 (adolescent)
    81(a)
    1 ↔ 1
    6(38213876-38266274)
    zebrafish
    (Danio rerio)
    Actinopterygii nphp36
    nephronophthisis 3
    71(a)
    1 ↔ 1
    24(9413140-9464727) ENSDARG00000078261
    fruit fly
    (Drosophila melanogaster)
    Insecta Klc6
    Kinesin light chain
    25(a)
    1 → many
    3L(12739716-12743156)
    worm
    (Caenorhabditis elegans)
    Secernentea klc-26
    klc-16
    Protein KLC-1, isoform b
    24(a)
    21(a)
    many ↔ many
    many ↔ many
    V(5575410-5581713) WBGene00002215
    IV(11083735-11086053) WBGene00002214
            Species with no ortholog for NPHP3-ACAD11

    ENSEMBL Gene Tree for NPHP3-ACAD11 (if available)
    TreeFam Gene Tree for NPHP3-ACAD11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NPHP3-ACAD11 gene
    KLC22  ENSG000002565002  KLC42  KLC32  KLC12  

    NPHP3-ACAD11 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NPHP3-ACAD11 (see all 362)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs8215721,2
    C,H--132340858(+) AGGAAT/CGTAAC 1 -- nc-transcript-variantese319Minor allele frequency- C:0.00MN NS EA NA WA CSA EU 6839
    rs1868183141,2
    --132361052(+) TACCCA/GAAGCT 1 -- int10--------
    rs1156461921,2
    C,F--132361116(+) TCATAC/TAGCAA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1435157161,2
    --132361148(+) GTCTCC/TAGTCC 1 -- int10--------
    rs1923463841,2
    --132361192(+) CTTATC/TGTGTG 1 -- int10--------
    rs1471789581,2
    C--132361243(+) TAGAGC/TTTACC 1 -- int10--------
    rs1132898201,2
    C,F--132361390(+) GGATAC/G/TGTATG 1 -- int11CSA 1
    rs1150399541,2
    C--132361484(+) GGAGGG/TGGGAT 1 -- int10--------
    rs744078791,2
    C,F--132361548(+) CATGTG/AGAAAA 1 -- int11Minor allele frequency- A:0.05WA 118
    rs168394931,2
    C,F,H--132361574(+) AGATTA/CGAAAA 1 -- int114Minor allele frequency- C:0.06NA NS EA WA 1108

    HapMap Linkage Disequilibrium report for NPHP3-ACAD11 (132276982 - 132441303 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NPHP3-ACAD11:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675190CNV Deletion23128226
    esv2669271CNV Deletion23128226
    nsv4014CNV Insertion18451855
    nsv829728CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    UniProtKB/Swiss-Prot: NPHP3_HUMAN, Q7Z494
  • Nephronophthisis 3 (NPHP3) [MIM:604387]: An autosomal recessive disorder resulting in end-stage renal
    disease. It is characterized by polyuria, polydipsia, anemia. Onset of terminal renal failure occurr
    significantly later (median age, 19 years) than in juvenile nephronophthisis. Renal pathology is characterized by
    alterations of tubular basement membranes, tubular atrophy and dilation, sclerosing tubulointerstitial
    nephropathy, and renal cyst development predominantly at the corticomedullary junction. Note=The disease is
    caused by mutations affecting the gene represented in this entry
  • Renal-hepatic-pancreatic dysplasia 1 (RHPD1) [MIM:208540]: A disease characterized by cystic
    malformations of the kidneys, liver, and pancreas. The pathological findings consist of multicystic dysplastic
    kidneys, dilated and dysgenetic bile ducts, a dysplastic pancreas with dilated ducts, cysts, fibrosis and
    inflammatory infiltrates. Note=The disease is caused by mutations affecting the gene represented in this entry
  • Meckel syndrome 7 (MKS7) [MIM:267010]: A disorder characterized by a combination of renal cysts and
    variably associated features including developmental anomalies of the central nervous system (typically
    encephalocele), hepatic ductal dysplasia and cysts, and polydactyly. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 10 diseases for NPHP3-ACAD11:    
    About MalaCards
    nephronophthisis 3    renal-hepatic-pancreatic dysplasia    nephronophthisis    situs inversus
    retinal degeneration    retinitis    multiple myeloma    myeloma
    hepatitis    pancreatitis


    NPHP3-ACAD11 for disorders           About GeneDecksing


    Export disorders for NPHP3-ACAD11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NPHP3-ACAD11 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with NPHP3-ACAD11)
        Utopia: connect your pdf to the dynamic
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    1. Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis. (PubMed id 12872122)1, 2 Olbrich H.... Omran H. (Nat. Genet. 2003)
    2. Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. (PubMed id 12056414)1, 2 Ohara O.... Koseki H. (DNA Res. 2002)
    3. Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. (PubMed id 23418306)2 Frank V.... Bergmann C. (Hum. Mol. Genet. 2013)
    4. ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. (PubMed id 23793029)2 Hoff S....Lienkamp S.S. (Nat. Genet. 2013)
    5. Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. (PubMed id 22863007)2 Chaki M....Hildebrandt F. (Cell 2012)
    6. An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. (PubMed id 22085962)2 Wright K.J.... Jackson P.K. (Genes Dev. 2011)
    7. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (PLoS ONE 2010)
    8. Nephrocystin-3 is required for ciliary function in zebrafish embryos. (PubMed id 20462968)2 Zhou W.... Hildebrandt F. (Am. J. Physiol. 2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic- pancreatic dysplasia. (PubMed id 18371931)2 Bergmann C.... Omran H. (Am. J. Hum. Genet. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 100532724 HGNC: 48351 Ensembl:ENSG00000113971 euGenes: HUgn100532724 ECgene: NPHP3-ACAD11
    H-InvDB: NPHP3-ACAD11

    (According to HUGE)
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    HUGE: KIAA2000

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NPHP3-ACAD11 gene:
    Search GeneIP for patents involving NPHP3-ACAD11

    GeneCards and IP:
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