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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NPFF Gene

protein-coding   GIFtS: 55
GCID: GC12M053896

Neuropeptide FF-Amide Peptide Precursor

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neuropeptide FF-Amide Peptide Precursor1 2
FMRFAL2
Pro-FMRFamide-Related Neuropeptide FF2

External Ids:    HGNC: 79011   Entrez Gene: 86202   Ensembl: ENSG000001395747   OMIM: 6046435   UniProtKB: O151303   

Export aliases for NPFF gene to outside databases

Previous GC identifers: GC12M054012 GC12M053618 GC12M052186 GC12M050940


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NPFF Gene:
FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the
modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two
active peptides with similar function. (provided by RefSeq, Jul 2008)

GeneCards Summary for NPFF Gene: 
NPFF (neuropeptide FF-amide peptide precursor) is a protein-coding gene. Diseases associated with NPFF include neonatal abstinence syndrome, and opioid abuse, and among its related super-pathways are Signaling by GPCR and GPCR ligand binding. GO annotations related to this gene include neuropeptide hormone activity and receptor binding.

UniProtKB/Swiss-Prot: NPFF_HUMAN, O15130
Function: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of
morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the
pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels

Gene Wiki entry for NPFF Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NPFF gene promoter:
         p53   Sp1   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNPFF promoter sequence
   Search SABiosciences Chromatin IP Primers for NPFF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPFF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

NPFF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPFF gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M053896:  view genomic region     (about GC identifiers)

Start:
53,900,472 bp from pter      End:
53,902,004 bp from pter
Size:
1,533 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NPFF_HUMAN, O15130 (See protein sequence)
Recommended Name: FMRFamide-related peptides precursor  
Size: 113 amino acids; 12440 Da
Subcellular location: Secreted

Explore the universe of human proteins at neXtProt for NPFF: NX_O15130

Explore proteomics data for NPFF at MOPED 

NPFF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

NPFF Protein Expression

REFSEQ proteins: NP_003708.1  
ENSEMBL proteins: 
 ENSP00000267017  
Reactome Protein details: O15130
Human Recombinant Protein Products for NPFF: 
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Cloud-Clone Corp. Proteins for NPFF 

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--
GO:0005615extracellular space IEA--
GO:0030425dendrite IEA--
GO:0031982vesicle IEA--
GO:0043204perikaryon IEA--

NPFF for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for NPFF


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
ENDOLIG: Endogenous ligands

1 InterPro protein domain:
 IPR008065 FMRFamid-related_peptide

Graphical View of Domain Structure for InterPro Entry O15130

ProtoNet protein and cluster: O15130

1 Blocks protein domain: IPB008065 FMRFamide-related peptide precursor signature

UniProtKB/Swiss-Prot: NPFF_HUMAN, O15130
Similarity: Belongs to the FARP (FMRFamide related peptide) family


NPFF for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: NPFF_HUMAN, O15130
Function: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of
morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the
pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels

     Genatlas biochemistry entry for NPFF:
FMRF-amide related peptides,precursor

     Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001664G-protein coupled receptor binding IEA--
GO:0005102receptor binding TAS10851242
GO:0005184neuropeptide hormone activity IEA--
     
NPFF for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for NPFF 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NPFF

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NPFF 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NPFF 

miRNA
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for NPFF About                                                                                                See pathways by source

SuperPathContained pathways About
1Signaling by GPCR
Signaling by GPCR0.90
Signal Transduction0.55
GPCR downstream signaling0.90
2Class A/1 (Rhodopsin-like receptors)
Class A/1 (Rhodopsin-like receptors)0.71
Peptide ligand-binding receptors0.60
GPCR ligand binding0.71
3G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK0.90
G alpha (q) signalling events0.90
4Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q
Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q0.46
5Orexin and neuropeptides FF and QRFP bind to their respective receptors
Orexin and neuropeptides FF and QRFP bind to their respective receptors

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 EMD Millipore Pathway for NPFF
    Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q


5/9        Reactome Pathways for NPFF (see all 9)
    GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Orexin and neuropeptides FF and QRFP bind to their respective receptors
Signaling by GPCR



NPFF for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NPFF

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/124 Interacting proteins for NPFF (O151303 ENSP000002670174) via UniProtKB, MINT, STRING, and/or I2D (see all 124)
InteractantInteraction Details
GeneCardExternal ID(s)
NPFFR1Q9GZQ63, ENSP000002779424I2D: score=1 STRING: ENSP00000277942
NPYP013033, ENSP000002421524I2D: score=1 STRING: ENSP00000242152
NPFFR2Q9Y5X53, ENSP000003078224I2D: score=1 STRING: ENSP00000307822
ADRBK1ENSP000003122624STRING: ENSP00000312262
CASRENSP000002961544STRING: ENSP00000296154
About this table

Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002438acute inflammatory response to antigenic stimulus IEA--
GO:0007204elevation of cytosolic calcium ion concentration IEA--
GO:0007218neuropeptide signaling pathway IEA--
GO:0007268synaptic transmission TAS9224703
GO:0010459negative regulation of heart rate IEA--

NPFF for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

NPFF for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NPFF

10/14 Novoseek inferred chemical compound relationships for NPFF gene (see all 14)    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
npff 99 360 16572434 (10), 19922753 (9), 16515822 (9), 18823989 (7) (see all 62)
rfamide 91.5 18 18823948 (2), 12606605 (1), 14960341 (1), 12012424 (1) (see all 9)
onpf 91.1 4 16572434 (1), 12149260 (1)
(125)i-ylfqpqrfamide 91.1 1 7716061 (1)
bibp3226 83.5 3 15127947 (1), 11325787 (1), 19958467 (1)
deltorphin i 78.1 1 15608144 (1)
fmrfamide 77.8 18 12668052 (3), 10798398 (2), 16516345 (1), 10851242 (1) (see all 7)
opiate 56.9 9 7716061 (2), 11334572 (1), 8804117 (1), 16515822 (1) (see all 5)
naltrindole 55.3 2 11179595 (1), 15804369 (1)
morphine 47 11 9593588 (4), 9203557 (1), 17597204 (1), 17936900 (1) (see all 6)

Search CenterWatch for drugs/clinical trials and news about NPFF

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NPFF gene: 
NM_003717.2  

Unigene Cluster for NPFF:

Neuropeptide FF-amide peptide precursor
Hs.733076  [show with all ESTs]
Unigene Representative Sequence: BC035758
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000448979 ENST00000267017(uc001sdw.1)

miRNA
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Inhib. RNA
Products:
     
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OriGene RNAi products in human, mouse, rat for NPFF
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPFF
Clone
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GenScript: all cDNA clones in your preferred vector: NPFF (NM_003717)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPFF
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPFF
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Primer
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OriGene qPCR primer pairs and template standards for NPFF
OriGene qSTAR qPCR primer pairs in human, mouse for NPFF
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPFF
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPFF

Additional mRNA sequence: 

AF005271.1 BC035758.1 

2 DOTS entries:

DT.410741  DT.92416730 

24/64 AceView cDNA sequences (see all 64):

CK823994 AA336101 CK824018 BX281139 AA805513 BU947733 AI126980 AA325498 
AW958164 AA024691 BM722845 BM876120 BM875416 BU073391 AA232243 BM565585 
BM313882 BC035758 AW779972 BM510791 AW270106 AA284471 AI381942 BM509291 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for NPFF    About this scheme

ExUns: 1 ^ 2 ^ 3
SP1:                  
SP2:                  


ECgene alternative splicing isoforms for NPFF

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NPFF expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CAAGGTCCAC
NPFF Expression
About this image


See NPFF Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NPFF

SOURCE GeneReport for Unigene cluster: Hs.733076
    SABiosciences Expression via Pathway-Focused PCR Array including NPFF: 
          Neurotrophins & Receptors in human mouse rat

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPFF

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for NPFF gene from 2/4 species (see all 4)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Npff1 , 5 neuropeptide FF-amide peptide precursor1, 5 75(n)1
64.81(a)1
  15 (57.65 cM)5
546151  NM_018787.11  NP_061257.11 
 1025238435 
lizard
(Anolis carolinensis)
Reptilia NPFF6
neuropeptide FF-amide peptide precursor
40(a)
1 ↔ 1
2(73123979-73137381)


ENSEMBL Gene Tree for NPFF (if available)
TreeFam Gene Tree for NPFF (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10 SNPs in NPFF are shown    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0491834
----see VAR_0491832 W R mis40--------
rs115588251,2
C,H--53900883(+) ACCCAG/AAGGTC 2 /S /F mis1 ese36Minor allele frequency- A:0.00NS EA NA 520
rs1386785001,2
C--53900920(+) GCTGTC/GTTCCT 2 H D mis11Minor allele frequency- G:0.00NA 4550
rs1158077051,2
C--53901094(+) AGAACC/ATAGAG 1 -- int11Minor allele frequency- A:0.01WA 118
rs81925931,2
C,F,H--53901105(-) TGAGAC/TTTGTG 1 -- int1 ese39Minor allele frequency- T:0.02NS EA NA 812
rs2013196341,2
--53901135(+) TGATAG/TGGGGA 1 -- int10--------
rs1463572941,2
----53900836(+) GCTCCG/AGCCAG 2 /R /W mis11Minor allele frequency- A:0.00NA 4552
rs3733484831,2
----53900941(+) GGGGGC/TATCAG 1 -- int10--------
rs3708325771,2
----53900748(+) CCTCTA/GCCTCC 1 -- int10--------
rs3695992921,2
----53900823(+) ACAGGA/GAGGCT 2 S F mis10--------

HapMap Linkage Disequilibrium report for NPFF (53900472 - 53902004 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for NPFF: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing NPFF
DNA2.0 Custom Variant and Variant Library Synthesis for NPFF

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 604643    OMIM disorders: --

10 diseases for NPFF:    About MalaCards
neonatal abstinence syndrome    opioid abuse    chronic pain    opiate dependence
agnosia    choroiditis    neuroblastoma    parkinson's disease
hypertension    neuronitis

4 diseases from the University of Copenhagen DISEASES database for NPFF:
Pain agnosia     Opiate dependence     Opioid abuse     Withdrawal disorder

NPFF for disorders           About GeneDecksing


Congresses - knowledge worth sharing:  
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

Export disorders for NPFF gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for NPFF gene, integrated from 9 sources (see all 85):
(articles sorted by number of sources associating them with NPFF)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. (PubMed id 9224703)1, 2, 3, 9 Perry S.J.... Burke J.F. (1997)
  2. Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF. (PubMed id 11587714)1, 2, 9 Catarsi S.... Seguela P. (2001)
  3. Pulsatile secretion of neuropeptide FF into human blood. (PubMed id 9786165)1, 9 Sundblom D.M....Fyhrquist F. (1998)
  4. Neuropeptide FF, a mammalian neuropeptide with multiple functions. (PubMed id 8804117)1, 9 Panula P....Wasowicz K. (1996)
  5. Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line. (PubMed id 16336216)1, 9 Anko M.L. and Panula P. (2006)
  6. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. (PubMed id 10851242)1, 9 Elshourbagy N.A....Sarau H.M. (2000)
  7. Neuropeptide FF-like immunoreactivity in human plasma. (PubMed id 7784266)1, 9 Sundblom D.M....Fyhrquist F. (1995)
  8. Physical association between neuropeptide FF and micro-opioid receptors as a possible molecular basis for anti-opioid activity. (PubMed id 17224450)1, 9 Roumy M....Mollereau C. (2007)
  9. Identification and characterization of two G protein-coupled receptors for neuropeptide FF. (PubMed id 11024015)1, 9 Bonini J.A....Borowsky B. (2000)
  10. Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus. (PubMed id 12609745)1, 9 Laemmle B....Wieland H.A. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 8620 HGNC: 7901 AceView: NPFF Ensembl:ENSG00000139574 euGenes: HUgn8620
ECgene: NPFF H-InvDB: NPFF

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for NPFF Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for NPFF gene:
Search GeneIP for patents involving NPFF

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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