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NPEPL1 Gene

protein-coding   GIFtS: 51
GCID: GC20P057267

Aminopeptidase-Like 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Aminopeptidase-Like 11 2 3     KIAA19743
bA261P9.22     R5
Probable Aminopeptidase NPEPL12     EC 3.4.118
EC 3.4.11.-3     EC 3.4.11.18

External Ids:    HGNC: 162441   Entrez Gene: 797162   Ensembl: ENSG000002154407   OMIM: 6052875   UniProtKB: Q8NDH33   

Export aliases for NPEPL1 gene to outside databases

Previous GC identifers: GC20P056995 GC20P057905 GC20P057952 GC20P057953 GC20P056700 GC20P054059


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NPEPL1 Gene:
NPEPL1 (aminopeptidase-like 1) is a protein-coding gene. GO annotations related to this gene include manganese ion binding and metalloexopeptidase activity. An important paralog of this gene is LAP3.

UniProtKB/Swiss-Prot: PEPL1_HUMAN, Q8NDH3
Function: Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the NPEPL1 gene promoter:
         c-Fos   NF-1   AP-1   FOXO3   FOXO3b   CREB   POU2F1   POU2F1a   Chx10   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNPEPL1 promoter sequence
   Search Chromatin IP Primers for NPEPL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NPEPL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.32   Ensembl cytogenetic band:  20q13.32   HGNC cytogenetic band: 20q13.32

NPEPL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPEPL1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P057267:  view genomic region     (about GC identifiers)

Start:
57,264,187 bp from pter      End:
57,294,294 bp from pter
Size:
30,108 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PEPL1_HUMAN, Q8NDH3 (See protein sequence)
Recommended Name: Probable aminopeptidase NPEPL1  
Size: 523 amino acids; 55861 Da
Cofactor: Zinc or manganese
Sequence caution: Sequence=AK307771; Type=Frameshift; Positions=35; Sequence=BAB13861.1; Type=Frameshift;
Positions=71;
Secondary accessions: A6NGZ0 B4DMW7 B7ZBN0 E9PN47 G5EA34 Q53G37 Q5W083 Q8TF28 Q8WUI2 Q9H1T6
Q9HAI5
Alternative splicing: 5 isoforms:  Q8NDH3-1   Q8NDH3-2   Q8NDH3-3   Q8NDH3-4   Q8NDH3-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NPEPL1: NX_Q8NDH3

Explore proteomics data for NPEPL1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for NPEPL1 (Q8NDH3)
     NTDAEGRL  EINNTDAEGRL 


    See NPEPL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001191801.1  NP_001191802.1  NP_078939.3  

    ENSEMBL proteins: 
     ENSP00000434810   ENSP00000437112   ENSP00000348395   ENSP00000436265  

    NPEPL1 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NPEPL1

     
    Search eBioscience for Proteins for NPEPL1 

    NPEPL1 Antibody Products:

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    Cloud-Clone Corp. ELISAs for NPEPL1
    Cloud-Clone Corp. CLIAs for NPEPL1
    Search eBioscience for ELISAs for NPEPL1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: Aminopeptidase-like 1
    Aminopeptidases

    2 InterPro protein domains:
     IPR000819 Peptidase_M17_C
     IPR011356 Leucine_aapep/pepB

    Graphical View of Domain Structure for InterPro Entry Q8NDH3

    ProtoNet protein and cluster: Q8NDH3

    2 Blocks protein domains:
    IPB000408 Regulator of chromosome condensation
    IPB000819 Cytosol aminopeptidase


    UniProtKB/Swiss-Prot: PEPL1_HUMAN, Q8NDH3
    Similarity: Belongs to the peptidase M17 family


    Find genes that share domains with NPEPL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PEPL1_HUMAN, Q8NDH3
    Function: Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides

         Enzyme Numbers (IUBMB): EC 3.4.11.-1 EC 3.4.11.12 EC 3.4.112

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004177aminopeptidase activity IEA--
    GO:0008235metalloexopeptidase activity IEA--
    GO:0030145manganese ion binding IEA--
         
    Find genes that share ontologies with NPEPL1           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for NPEPL1:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NPEPL1
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    miRNA
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    miRTarBase miRNAs that target NPEPL1:
    hsa-mir-335-5p (MIRT017692), hsa-mir-148b-3p (MIRT019391)

    Block miRNA regulation of human, mouse, rat NPEPL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NPEPL1 (see all 27):
    hsa-miR-148b hsa-let-7d hsa-miR-202 hsa-miR-301a hsa-let-7c hsa-let-7g hsa-let-7a hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidNPEPL1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NPEPL1
    Predesigned siRNA for gene silencing in human, mouse, rat NPEPL1

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPEPL1

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPEPL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with NPEPL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NPEPL1
    Interactions:

        Search GeneGlobe Interaction Network for NPEPL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for NPEPL1 (Q8NDH33 ENSP000003483954) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FABP3P054133I2D: score=4 
    TPI1ENSP000003799334STRING: ENSP00000379933
    PTSENSP000002803624STRING: ENSP00000280362
    TREHENSP000002640294STRING: ENSP00000264029
    AHCYENSP000002174264STRING: ENSP00000217426
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----

    Find genes that share ontologies with NPEPL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NPEPL1 (PEPL1)

    1 HMDB Compound for NPEPL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Manganesemanganese 7439-96-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NPEPL1 gene (3 alternative transcripts): 
    NM_001204872.1  NM_001204873.1  NM_024663.3  

    Unigene Cluster for NPEPL1:

    Aminopeptidase-like 1
    Hs.654868  [show with all ESTs]
    Unigene Representative Sequence: NR_037945
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000525967 ENST00000525817 ENST00000356091 ENST00000529976(uc002xzp.3)
    ENST00000527587(uc010zzr.2 uc010gjo.2 uc010zzs.1) ENST00000533788
    ENST00000527081 ENST00000525068 ENST00000532531
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NPEPL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NPEPL1 (see all 27):
    hsa-miR-148b hsa-let-7d hsa-miR-202 hsa-miR-301a hsa-let-7c hsa-let-7g hsa-let-7a hsa-miR-520g
    SwitchGear 3'UTR luciferase reporter plasmidNPEPL1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NPEPL1
    Predesigned siRNA for gene silencing in human, mouse, rat NPEPL1
    Clone
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    OriGene ORF clones in mouse, rat for NPEPL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NPEPL1 (NM_018226)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPEPL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPEPL1
    Primer
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    OriGene qPCR primer pairs and template standards for NPEPL1
    OriGene qSTAR qPCR primer pairs in human, mouse for NPEPL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NPEPL1
      QuantiTect SYBR Green Assays in human, mouse, rat NPEPL1
      QuantiFast Probe-based Assays in human, mouse, rat NPEPL1

    Additional mRNA sequence: 

    AK021645.1 AK096873.1 AK124479.1 AK126390.1 AK223094.1 AK297667.1 AK307771.1 AK315684.1 
    BC020507.1 BC068074.1 NR_037945.1 

    16 DOTS entries:

    DT.95173595  DT.101979526  DT.95173597  DT.91871691  DT.100775145  DT.95173596  DT.120836141  DT.433571 
    DT.100775146  DT.412976  DT.120836094  DT.100810187  DT.102822900  DT.95092713  DT.95173599  DT.97814099 

    Selected AceView cDNA sequences (see all 484):

    BQ220461 AI493393 BQ641592 AW849311 BU180474 AI823467 BE937267 BC019042 
    AI699125 BE856414 BU737996 BG149517 CF528596 AI356379 AA291733 AV728943 
    BM894060 BG112896 BF593830 BM450515 AA344951 BM991878 AW963223 BM993587 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NPEPL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCTCGCCTG
    NPEPL1 Expression
    About this image

    NPEPL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NPEPL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654868

    UniProtKB/Swiss-Prot: PEPL1_HUMAN, Q8NDH3
    Tissue specificity: Ubiquitously expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPEPL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NPEPL1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Npepl11 , 5 aminopeptidase-like 11, 5 87.83(n)1
    94.84(a)1
      2 (97.87 cM)5
    2289611  NM_213733.21  NP_998898.11 
     1741103495 
    chicken
    (Gallus gallus)
    Aves NPEPL11 aminopeptidase-like 1 76.29(n)
    87.76(a)
      419314  XM_417486.4  XP_417486.2 
    lizard
    (Anolis carolinensis)
    Reptilia NPEPL16
    aminopeptidase-like 1
    78(a)
    1 ↔ 1
    GL343475.1(183111-203622)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.261072 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_078939.1 (H.sapiens) aminopeptidase-like 1 [Homo sapiens] less 78.21(n)    CD328736.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi27h092 wufi27h09 78.21(n)   334040  CK029729.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BcDNA:LD415483
    grsm1
    aminopeptidase3
    granny smith1
    65(a)3
    62.76(n)1
    64.65(a)1
      87D53
    415871  NM_141983.31  NP_650240.11 
    worm
    (Caenorhabditis elegans)
    Secernentea lap-11 , 3 Leucine aminopeptidase3
    lap-11
    49(a)3
    50.83(n)1
    48.22(a)1
      III(8471033-8473644)3
    1761851  NM_066453.31  NP_498854.11 


    ENSEMBL Gene Tree for NPEPL1 (if available)
    TreeFam Gene Tree for NPEPL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NPEPL1 gene
    LAP32  

    Find genes that share paralogs with NPEPL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    10 SNPs for NPEPL1    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs736281521,2
    C--57279560(+) ACATA-/TAAATCC 1 -- int10--------
    rs2007865281,2
    --57287163(+) TGTGT-/GTGTAC
            
    GTGTG
    1 -- int10--------
    rs339417271,2
    C--57287165(+) TGTGT-/A/GTAC
            
    GTGTG
    1 -- int10--------
    rs607274261,2
    C--57287167(+) TGTGT-/ACGT  
            
    GTGTG
    1 -- int10--------
    rs81162921,2,4
    ----see VAR_0597562 mis40--------
    rs60264681,2,4
    ----see VAR_0597572 mis40--------
    rs3676882691,2
    ----57266769(+) TTTTT-/TTCA  
            
    TTTTT
    1 -- us2k10--------
    rs3718202871,2
    ----57266770(+) TTTTT-/TCATTTTT 1 -- us2k10--------
    rs3772889771,2
    ----57266768(+) TTTTT-/TTTC  
            
    ATTTT
    1 -- us2k10--------
    rs1446287781,2
    ----57270074(+) TGTGT-/GTGTGT 1 -- int10--------

    HapMap Linkage Disequilibrium report for NPEPL1 (57264187 - 57294294 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for NPEPL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665738CNV Deletion23128226
    nsv513552CNV Insertion21212237
    esv2558295CNV Insertion19546169
    esv1198718CNV Insertion17803354
    nsv828762CNV Loss20364138
    nsv828761CNV Loss20364138
    nsv912963CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NPEPL1
    DNA2.0 Custom Variant and Variant Library Synthesis for NPEPL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605287    OMIM disorders: --


    Find genes that share disorders with NPEPL1           About GenesLikeMe


    Export disorders for NPEPL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NPEPL1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NPEPL1)
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    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. A whole genome screen for HIV restriction factors. (PubMed id 22082156)1 Liu L....McKnight A. (Retrovirology 2011)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79716 HGNC: 16244 AceView: STX16andNPEPL1 Ensembl:ENSG00000215440 euGenes: HUgn79716
    ECgene: NPEPL1 H-InvDB: NPEPL1

    (According to HUGE)
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    HUGE: KIAA1974

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NPEPL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NPEPL1 gene:
    Search GeneIP for patents involving NPEPL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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