Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NPDC1 Gene

protein-coding   GIFtS: 50
GCID: GC09M139933

neural proliferation, differentiation and control, 1
 Explore 1 disease affiliated with
NPDC1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NPDC1    

Aliases
for NPDC1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Neural Proliferation, Differentiation And Control, 11 2     DKFZp586J05231
CAB11 2 5     CAB2
CAB-1 2     CAB-12
NPDC-12 3     Neural Proliferation Differentiation And Control Protein 12

External Ids:    HGNC: 78991   Entrez Gene: 566542   Ensembl: ENSG000001072817   OMIM: 6057985   UniProtKB: Q9NQX53   

Export aliases for NPDC1 gene to outside databases

Previous GC identifers: GC09M131083 GC09M131623 GC09M133373 GC09M135291 GC09M137209 GC09M139053 GC09M109393


Summaries
for NPDC1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NPDC1_HUMAN, Q9NQX5
Function: Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell
proliferation. Might be involved in transcriptional regulation (By similarity)

Gene Wiki entry for NPDC1


Genomic Views
for NPDC1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_024000.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NPDC1 gene promoter:
         RFX1   GATA-3   NRSF form 1   SEF-1 (1)   NRSF form 2   GATA-1   GATA-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NPDC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

NPDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPDC1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M139933:  view genomic region     (about GC identifiers)

Start:
 139,933,909 bp from pter      End:
 139,940,676 bp from pter
Size:
 6,768 bases      Orientation:
 minus strand

Proteins
for NPDC1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NPDC1_HUMAN, Q9NQX5 (See protein sequence)
Recommended Name: Neural proliferation differentiation and control protein 1 precursor  
Size: 325 amino acids; 34516 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: Q5SPY8 Q9BTD6 Q9BXT3 Q9NQS2 Q9Y434

Explore the universe of human proteins at neXtProt for NPDC1: NX_Q9NQX5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NQX5

    • NPDC1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056207.3  
    ENSEMBL proteins: 
     ENSP00000360659   ENSP00000360660  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: NPDC1
    OriGene Protein Over-expression Lysate: NPDC1
    OriGene Custom Protein Services for NPDC1 
    GenScript Custom Purified and Recombinant Proteins Services for NPDC1
    Novus Biologicals NPDC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NPDC1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    NPDC1 for ontologies           About GeneDecksing



    NPDC1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for NPDC1 (NPDC-1)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NPDC1 
    GenScript Custom Superior Antibodies Services for NPDC1
    Novus Biologicals NPDC1 Antibodies
    Search for Antibodies for NPDC1 at Abcam  
    Uscn Antibodies for NPDC1
    ThermoFisher Antibodies for NPDC1

    Assay Products for NPDC1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NPDC1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for NPDC1

    Protein Domains /
    Families
    for NPDC1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NPDC1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009635 NPDC1

    Graphical View of Domain Structure for InterPro Entry Q9NQX5

    ProtoNet protein and cluster: Q9NQX5

    UniProtKB/Swiss-Prot: NPDC1_HUMAN, Q9NQX5
    Similarity: Belongs to the NPDC1/cab-1 family


    Function
    for NPDC1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NPDC1_HUMAN, Q9NQX5
    Function: Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell
    proliferation. Might be involved in transcriptional regulation (By similarity)

    miRNA
    Products:            		 OriGene 3'-UTR Clone: NPDC1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPDC1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NPDC1:
    hsa-miR-3119 hsa-miR-145
    SwitchGear 3'UTR luciferase reporter plasmid: NPDC1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPDC1 (see all 7)
    OriGene shRNA RFP: NPDC1
    OriGene siRNA: NPDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPDC1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NPDC1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NPDC1 (NM_015392)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPDC1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for NPDC1
    Search LifeMap BioReagents cell lines for NPDC1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPDC1

    Animal Models:
         Mouse knock-out Npdc1tm1Ce for NPDC1
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Npdc1):
     normal 

    NPDC1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NPDC1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NPDC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/13 Interacting proteins for NPDC1 (Q9NQX53 ENSP000003606604) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCND3P302813, ENSP000003620824I2D: score=2 STRING: ENSP00000362082
    CDK2P249413, ENSP000002669704I2D: score=2 STRING: ENSP00000266970
    E2F1Q010943, ENSP000003455714I2D: score=2 STRING: ENSP00000345571
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    MADDQ8WXG63, ENSP000003109334I2D: score=1 STRING: ENSP00000310933
    About this table

    Drugs & Compounds
    for NPDC1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NPDC1
    Search CenterWatch for drugs/clinical trials and news about NPDC1 

    Transcripts
    for NPDC1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NPDC1 gene: 
    NM_015392.3  

    Unigene Cluster for NPDC1:

    Neural proliferation, differentiation and control, 1
    Hs.719906  [show with all ESTs]
    Unigene Representative Sequence: AK054950
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371600(uc004cks.2) ENST00000371601(uc004ckt.2) ENST00000496498
    ENST00000472668 ENST00000488145 ENST00000485589

    miRNA
    Products:             		 OriGene 3'-UTR Clone: NPDC1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPDC1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NPDC1:
    hsa-miR-3119 hsa-miR-145
    SwitchGear 3'UTR luciferase reporter plasmid: NPDC1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPDC1 (see all 7)
    OriGene shRNA RFP: NPDC1
    OriGene siRNA: NPDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPDC1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NPDC1 (NM_015392)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPDC1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPDC1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NPDC1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPDC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPDC1

    Additional cDNA sequence: 

    AF272357.1 AF283247.1 AF285836.1 AF327349.1 AK054950.1 AK074793.1 AK225091.1 AL050221.1 
    BC004217.2 

    19 DOTS entries:

    DT.454337  DT.95164572  DT.95164571  DT.91639713  DT.121190504  DT.92445645  DT.95164574  DT.100838416 
    DT.121190508  DT.100773155  DT.102832498  DT.102832499  DT.121190471  DT.92445651  DT.95164576  DT.95206845 
    DT.121190515  DT.95234488  DT.97848219 

    24/413 AceView cDNA sequences (see all 413):

    AW157080 AI923915 CD723142 AI598080 AI969161 CR621502 AA994691 AK074793 
    BE168727 CA312110 CB242775 BC004217 CB153286 BX366082 CR626507 CA392783 
    AI799722 AI878983 CR597998 BQ050832 BM822565 H06128 BU607324 CR595396 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NPDC1 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11
    SP1:                    -                 -                                                     -                     
    SP2:                    -     -           -                                                     -                     
    SP3:                                      -                                                     -                     
    SP4:                                                                                            -           -         
    SP5:                                      -     -                                                                     


    ECgene alternative splicing isoforms for NPDC1

    Expression
    for NPDC1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NPDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGAACCGTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NPDC1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NPDC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NPDC1

    SOURCE GeneReport for Unigene cluster: Hs.719906

    UniProtKB/Swiss-Prot: NPDC1_HUMAN, Q9NQX5
    Tissue specificity: Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe

        SABiosciences Custom PCR Arrays for NPDC1
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPDC1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NPDC1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPDC1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPDC1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPDC1

    Orthologs
    for NPDC1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NPDC1 gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Npdc11 , 5 neural proliferation, differentiation and control gene more1, 5 78.09(n)1
    78.7(a)1    		   2 (17.23 cM)5
    181461  NM_008721.31  NP_032747.21 
     253993515 
    chicken
    (Gallus gallus)    		 Aves NPDC11 neural proliferation, differentiation and control, more 62.85(n)
    54.96(a)    		   770620  XM_001233958.2  XP_001233959.2 
    lizard
    (Anolis carolinensis)    		 Reptilia NPDC16
    		 --
    		 67(a)
    		 1 ↔ 1
    		 AAWZ02039732(3830-6716)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.106202 Transcribed sequence with weak similarity to protein more 75.64(n)    AL972580.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii sbcb10302 sbcb1030 77.44(n)   387312  BG307328.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Atf-26
    		 Activating transcription factor-2
    		 10(a)
    		 1 ↔ 1
    		 2R(20757590-20768744)
    worm
    (Caenorhabditis elegans)    		 Secernentea cab-16
    		 Protein cab-1
    		 14(a)
    		 1 ↔ 1
    		 X(12199587-12212981)


    ENSEMBL Gene Tree for NPDC1 (if available)
    TreeFam Gene Tree for NPDC1 (if available) 

    Paralogs
    for NPDC1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NPDC1 gene

    NPDC1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NPDC1
    PGOHUM00000238707


    Genomic Variants
    for NPDC1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/169 NCBI SNPs in NPDC1 are shown (see all 169)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1445565981,2
    		--139933431(+) CACACA/GGGTAC 1 -- int10--------
    rs107815341,2
    		C,F,A,--139933589(+) CAGCCT/CTCTTT 1 -- int110Minor allele frequency- C:0.28NA WA EA 372
    rs1177527881,2
    		--139933604(+) CACAGG/CATGGG 1 -- int11Minor allele frequency- C:0.01NA 120
    rs70265041,2
    		C,F,A,H,--139933617(+) CTTCCG/AGGCCG 1 -- int110Minor allele frequency- A:0.09NA WA CSA EA 373
    rs1474264681,2
    		--139933698(+) GCAGGA/GGTGAG 1 -- int10--------
    rs1831479221,2
    		--139933842(+) CAGGGA/GTCCGT 1 -- int10--------
    rs2005755281,2
    		C--139933882(-) AATCTC/TCCACC 1 -- int10--------
    rs1870753921,2
    		--139933976(+) CCTGCA/GCTCTA 1 -- ut310--------
    rs1484621851,2
    		--139933984(+) CTACGA/GTTCTC 1 -- ut310--------
    rs66051,2
    		C,F,A,H,--139934020(-) CTGTTC/TGGTTT 1 -- ut3122Minor allele frequency- T:0.19EA MN NA NS 3655

    HapMap Linkage Disequilibrium report for NPDC1 (139933909 - 139940676 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for NPDC1
         2 CNVs: 30350 5415

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPDC1
    DNA2.0 Custom Variant and Variant Library Synthesis for NPDC1

    Disorders / Diseases
    for NPDC1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NPDC1 for disorders           About GeneDecksing

    OMIM gene information: 605798    OMIM disorders: --

    1 disease for NPDC1:    About MalaCards
    neuronitis


    Export disorders for NPDC1 gene to outside databases

    Publications
    for NPDC1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NPDC1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with NPDC1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization and tissue expression of a novel human gene npdc1. (PubMed id 11245976)1, 2, 3 Qu X.... He F. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Functional analysis of the NPDC-1 gene. (PubMed id 15563841)1, 9 Evrard C....Rouget P. (2004)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    8. The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. (PubMed id 17577209)1 Miele A....Stein J.L. (2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    External Searches for NPDC1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NPDC1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56654 HGNC: 7899 AceView: NPDC1 Ensembl:ENSG00000107281 euGenes: HUgn56654
    ECgene: NPDC1 H-InvDB: NPDC1

    Other Databases showing NPDC1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NPDC1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NPDC1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NPDC1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for NPDC1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NPDC1 gene:
    Search GeneIP for patents involving NPDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for NPDC1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for NPDC1 (NPDC-1)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for NPDC1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPDC1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPDC1  
     OriGene Protein Over-expression Lysate for NPDC1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for NPDC1   OriGene 3'-UTR Clone for NPDC1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPDC1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for NPDC1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NPDC1   OriGene Custom Protein Services for NPDC1  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NPDC1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPDC1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPDC1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPDC1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPDC1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPDC1
     GenScript Custom Purified and Recombinant Proteins Services for NPDC1 GenScript cDNA clones with any tag delivered in your preferred vector for NPDC1
     GenScript Custom Assay Services for NPDC1 GenScript Custom Superior Antibodies Services for NPDC1
     GenScript Custom overexpressing Cell Line Services for NPDC1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NPDC1 promoter
     Search Chromatin IP Primers for NPDC1
     RT2 qPCR Primer Assay in human, mouse, rat NPDC1
     GNC Network for NPDC1
     SABiosciences Custom PCR Arrays for NPDC1
     Search Tocris compounds for NPDC1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NPDC1 antibodies
     NPDC1 lysates
     Search for Antibodies for NPDC1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NPDC1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     NPDC1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for NPDC1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPDC1
     SwitchGear 3'UTR luciferase reporter plasmids for NPDC1
     Browse SwitchGear Promoter luciferase reporter plasmids for NPDC1
     ThermoFisher Antibodies for NPDC1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPDC1
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      NPDC1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4