Aliases for NPAS3 Gene
External Ids for NPAS3 Gene
Previous GeneCards Identifiers for NPAS3 Gene
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
GeneCards Summary for NPAS3 Gene
NPAS3 (Neuronal PAS Domain Protein 3) is a Protein Coding gene. Diseases associated with NPAS3 include Holoprosencephaly 8 and Learning Disability. GO annotations related to this gene include signal transducer activity and protein dimerization activity. An important paralog of this gene is NPAS1.
UniProtKB/Swiss-Prot for NPAS3 Gene
May play a broad role in neurogenesis. May control regulatory pathways relevant to schizophrenia and to psychotic illness (By similarity).