External Ids for NOTO Gene
Previous GeneCards Identifiers for NOTO Gene
GeneCards Summary for NOTO Gene
UniProtKB/Swiss-Prot for NOTO Gene
Transcription regulator acting downstream of both FOXA2 and Brachyury (T) during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate (By similarity).