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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NOSIP Gene

protein-coding GIFtS: 55
GCID: GC19M050058

Nitric Oxide Synthase Interacting Protein

6 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Nitric Oxide Synthase Interacting Protein¹ ²
ENOS-Interacting Protein² ³
Nitric Oxide Synthase-Interacting Protein²

External Ids:	HGNC: 17946¹	Entrez Gene: 51070²	Ensembl: ENSG00000142546⁷	UniProtKB: Q9Y314³

Export aliases for NOSIP gene to outside databases

Previous GC identifers: GC19M050717 GC19M050427 GC19M054734 GC19M054751 GC19M054752 GC19M054753 GC19M046436

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NOSIP Gene:

The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial

and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that

encode the same protein. (provided by RefSeq, Aug 2012)

GeneCards Summary for NOSIP Gene:

NOSIP (nitric oxide synthase interacting protein) is a protein-coding gene. Diseases associated with NOSIP include alcoholic hepatitis, and endotheliitis, and among its related super-pathways are Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: NOSIP_HUMAN, Q9Y314

Function: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin

cytoskeleton and inhibiting their enzymatic activity

Gene Wiki entry for NOSIP Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NT_011109.16 NC_018930.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NOSIP gene promoter:
p53 STAT5A RelA NF-kappaB Egr-4 Egr-2 HOXA5 c-Myb Zic3 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NOSIP promoter sequence

Search SABiosciences Chromatin IP Primers for NOSIP

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOSIP

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.3

NOSIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOSIP gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M050058: view genomic region (about GC identifiers)

Start:	50,058,968 bp from pter	End:	50,093,519 bp from pter
Size:	34,552 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NOSIP_HUMAN, Q9Y314 (See protein sequence)

Recommended Name: Nitric oxide synthase-interacting protein

Size: 301 amino acids; 33172 Da

Subunit: Interacts with NOS1 and NOS3

Subcellular location: Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell

cycle

Secondary accessions: Q96FD2

Explore the universe of human proteins at neXtProt for NOSIP: NX_Q9Y314

Explore proteomics data for NOSIP at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q9Y314

NOSIP Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (2 alternative transcripts):

NP_001257889.1 NP_057037.1

ENSEMBL proteins:

ENSP00000470450 ENSP00000343497 ENSP00000470034 ENSP00000473109 ENSP00000471929

ENSP00000472103 ENSP00000471291 ENSP00000468974 ENSP00000375726

Reactome Protein details: Q9Y314
Human Recombinant Protein Products for NOSIP:

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	Cloud-Clone Corp. Proteins for NOSIP

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0005634	nucleus	IDA	--
GO:0005737	cytoplasm	IDA	15548660
GO:0005829	cytosol	TAS	--

NOSIP for ontologies About GeneDecksing

NOSIP Antibody Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

2 InterPro protein domains:

IPR013083 Znf_RING/FYVE/PHD

IPR016818 Nitric_oxide_synth-interacting

Graphical View of Domain Structure for InterPro Entry Q9Y314

ProtoNet protein and cluster: Q9Y314

1 Blocks protein domain: IPB003613 Zn-finger

UniProtKB/Swiss-Prot: NOSIP_HUMAN, Q9Y314

Domain: The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not

Similarity: Belongs to the NOSIP family

NOSIP for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: NOSIP_HUMAN, Q9Y314

Function: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin

cytoskeleton and inhibiting their enzymatic activity

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	11149895

NOSIP for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for NOSIP:

Increased cell number in S and

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for NOSIP

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genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOSIP

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOSIP

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for NOSIP About

See pathways by source

SuperPath

Contained pathways About

Metabolism of nitric oxide

Metabolism of nitric oxide

0.59

eNOS activation and regulation

0.59

Nanog in Mammalian ESC Pluripotency

eNOS Signaling

0.48

Metabolism

Metabolism

0.40

NOSIP mediated eNOS trafficking

NOSIP mediated eNOS trafficking

Pathways by source See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for NOSIP

eNOS Signaling

4 Reactome Pathways for NOSIP

	eNOS activation and regulation
	Metabolism of nitric oxide
	Metabolism
	NOSIP mediated eNOS trafficking

NOSIP for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for NOSIP

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/7 Interacting proteins for NOSIP (Q9Y314³ ENSP00000343497⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NOS1	P29475³, ENSP00000320758⁴	I2D: score=1 STRING: ENSP00000320758
EPOR	P19235³, ENSP00000222139⁴	I2D: score=1 STRING: ENSP00000222139
NOS3	P29474³, ENSP00000297494⁴	I2D: score=1 STRING: ENSP00000297494
BCAR3	O75815³, ENSP00000260502⁴	I2D: score=1 STRING: ENSP00000260502
LMLN	Q96KR4³	I2D: score=5

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0043086	negative regulation of catalytic activity	IDA	11149895
GO:0044281	small molecule metabolic process	TAS	--
GO:0046209	nitric oxide metabolic process	TAS	--
GO:0050999	regulation of nitric-oxide synthase activity	TAS	--
GO:0051001	negative regulation of nitric-oxide synthase activity	IDA	11149895

NOSIP for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NOSIP

Search CenterWatch for drugs/clinical trials and news about NOSIP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NOSIP gene (2 alternative transcripts):

NM_001270960.1 NM_015953.4

Unigene Cluster for NOSIP:

Nitric oxide synthase interacting protein

Hs.7236 [show with all ESTs]

Unigene Representative Sequence: BC047314

17 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000601015 ENST00000598820 ENST00000339093(uc002pol.3 uc010yay.1)

ENST00000596358 ENST00000601340 ENST00000596477 ENST00000598550 ENST00000599537

ENST00000598296 ENST00000594932 ENST00000600019 ENST00000598544 ENST00000599425

ENST00000598839 ENST00000601107 ENST00000593345 ENST00000391853(uc002pok.3)

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOSIP
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Additional mRNA sequence:

AF132959.1 AK092444.1 AK291535.1 AK300720.1 BC009299.2 BC010077.2 BC011249.1 BC047314.1

19 DOTS entries:

DT.99975462 DT.452105 DT.101984796 DT.87001719 DT.95261373 DT.40196975 DT.91770602 DT.91770604

DT.91770607 DT.95261374 DT.100733542 DT.100825128 DT.102841623 DT.121408966 DT.95084180 DT.95327946

DT.97817414 DT.97849044 DT.100808047

24/372 AceView cDNA sequences (see all 372):

AA147395 CB128803 BM995776 BM808037 BP372940 BM996788 BE782091 CA454253

BU556759 BM015960 BM694449 CF127048 CB109602 BM919394 AI148730 AA320721

BE743958 AI344201 BM558738 BU526794 CB126120 BM793482 BE560941 BC010077

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for NOSIP (see all 10) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6	^	7a	·	7b	^	8a	·	8b	·	8c	^	9a	·	9b	^	10	^	11	^	12a	·	12b
SP1:									-				-						-		-		-						-
SP2:					-				-				-						-		-		-						-
SP3:									-				-						-		-		-
SP4:					-				-				-																-
SP5:					-				-				-						-		-		-

ECgene alternative splicing isoforms for NOSIP

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NOSIP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GTGGACCCTG

About this image

See NOSIP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NOSIP

SOURCE GeneReport for Unigene cluster: Hs.7236

UniProtKB/Swiss-Prot: NOSIP_HUMAN, Q9Y314

Tissue specificity: Expressed in heart, brain and lung. Present in endothelial cells (at protein level)

SABiosciences Expression via Pathway-Focused PCR Arrays including NOSIP:

Hypertension in human mouse rat

Neurotoxicity in human mouse rat

Ubiquitin Ligases in human mouse rat

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NOSIP gene from 8/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nosip^{1 , 5}	nitric oxide synthase interacting protein^{1, 5}	85.83(n)¹ 90.7(a)¹		7 (29.10 cM)⁵ 66394¹ NM_025533.3¹ NP_079809.1¹ 45062429⁵
lizard (Anolis carolinensis)	Reptilia	NOSIP⁶	Uncharacterized protein	77(a)	1 ↔ 1	6(80453902-80464707)
African clawed frog (Xenopus laevis)	Amphibia	CA974674.1²	--	75.03(n)		CA974674.1
zebrafish (Danio rerio)	Actinopterygii	57043391²	--	79.03(n)		323049 57043391
fruit fly (Drosophila melanogaster)	Insecta	CG6179^{1 , 3}	CG6179¹	48(a)³ 60.02(n)¹ 53.04(a)¹		17A9³ 32819¹ NM_133060.2¹ NP_573288.1¹
worm (Caenorhabditis elegans)	Secernentea	R05G6.4¹	Protein R05G6.4	48.39(n) 48.28(a)		177526 NM_068813.5 NP_501214.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G61620¹	nitric oxide synthase-interacting protein	44.56(n) 34.05(a)		842458 NM_104844.2 NP_564781.1
rice (Oryza sativa)	Liliopsida	Os03g0279900¹	hypothetical protein	46.16(n) 33.45(a)		4332437 NM_001056270.1 NP_001049735.1

ENSEMBL Gene Tree for NOSIP (if available)
TreeFam Gene Tree for NOSIP (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150046263^1,2		--	50058276(+)	`GCTGCC/GCACTT`	2	--	ds500¹		0	--	--	--	--
rs77164262^1,2	C	--	50058337(+)	`AGACAC/TGTTCC`	2	--	ds500¹		0	--	--	--	--
rs139530582^1,2	C	--	50058339(+)	`ACACGC/TTCCTG`	2	--	ds500¹		0	--	--	--	--
rs117807116^1,2	F	--	50058430(+)	`AGTGGC/TGCACT`	2	--	ds500¹		1		EA	120
rs184849064^1,2		--	50058441(+)	`CACACA/GGTCTT`	2	--	ds500¹		0	--	--	--	--
rs147558794^1,2		--	50058601(+)	`ACCTCA/CGCCTC`	2	--	ds500¹		0	--	--	--	--
rs113342714^1,2	C,F	--	50058721(+)	`ATGTTA/GGCCAG`	2	--	ds500¹		1		CSA	3
rs188373996^1,2	C	--	50058742(+)	`AACTCC/TTGACC`	2	--	ut3¹		0	--	--	--	--
rs193159348^1,2		--	50058782(+)	`AAGTGC/TTGGGA`	2	--	ut3¹		0	--	--	--	--
rs184596678^1,2		--	50058859(+)	`TAGCCC/GGCTCT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NOSIP (50058968 - 50093519 bp)

Structural Variations
Database of Genomic Variants (DGV) 10 variations for NOSIP: About this table

Variant ID	Type	Subtype	PubMed ID
nsv912262	CNV	Loss	21882294
nsv912261	CNV	Loss	21882294
nsv912265	CNV	Loss	21882294
nsv833862	CNV	Loss	17160897
nsv833863	CNV	Loss	17160897
nsv828578	CNV	Loss	20364138
nsv833864	CNV	Gain	17160897
nsv9739	CNV	Gain+Loss	18304495
nsv833865	CNV	Gain+Loss	17160897
nsv469715	CNV	Complex	16826518

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOSIP

DNA2.0 Custom Variant and Variant Library Synthesis for NOSIP

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

6 diseases for NOSIP: About MalaCards

alcoholic hepatitis endotheliitis alcoholism hypertension

neuronitis hepatitis

NOSIP for disorders About GeneDecksing

Export disorders for NOSIP gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NOSIP gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with NOSIP)

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NOSIP, a novel modulator of endothelial nitric oxide synthase activity. (PubMed id 11149895)^{1, 2, 3} Dedio J....Mueller-Esterl W. (2001)
Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)^{1, 2, 3} Lai C.H....Lin W. (2000)
Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton. (PubMed id 16135813)^{1, 2, 9} Schleicher M.... Oess S. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. (PubMed id 15548660)^{1, 2} Dreyer J.... Kuner R. (2004)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)¹ Povlsen L.K....Choudhary C. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 51070	HGNC: 17946	AceView: NOSIP	Ensembl:ENSG00000142546	euGenes: HUgn51070
ECgene: NOSIP	H-InvDB: NOSIP

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NOSIP	Pharmacogenomics, SNPs, Pathways

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Patent Information for NOSIP gene:
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Nitric Oxide Synthase Interacting Protein

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Nitric Oxide Synthase Interacting Protein

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