Aliases for NOSIP Gene
Aliases for NOSIP Gene
External Ids for NOSIP Gene
- HGNC: 17946
- Entrez Gene: 51070
- Ensembl: ENSG00000142546
- OMIM: 616759
- UniProtKB: Q9Y314
Previous GeneCards Identifiers for NOSIP Gene
- GC19M050717
- GC19M050427
- GC19M054734
- GC19M054751
- GC19M054752
- GC19M054753
- GC19M050058
- GC19M046436
Summaries for NOSIP Gene
-
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]
GeneCards Summary for NOSIP Gene
NOSIP (Nitric Oxide Synthase Interacting Protein) is a Protein Coding gene. Among its related pathways are Metabolism and eNOS activation and regulation. GO annotations related to this gene include poly(A) RNA binding.
UniProtKB/Swiss-Prot for NOSIP Gene
-
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOSIP Gene
Genomics for NOSIP Gene
Regulatory Elements for NOSIP Gene
Enhancers for NOSIP Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around NOSIP on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the NOSIP gene promoter:
Regulatory Element Products
Genomic Location for NOSIP Gene
- Chromosome:
- 19
- Start:
- 49,555,468 bp from pter
- End:
- 49,590,262 bp from pter
- Size:
- 34,795 bases
- Orientation:
- Minus strand
Genomic View for NOSIP Gene
Genes around NOSIP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
NOSIP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NOSIP Gene
Proteins for NOSIP Gene
-
Protein details for NOSIP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y314-NOSIP_HUMAN
- Recommended name:
- Nitric oxide synthase-interacting protein
- Protein Accession:
- Q9Y314
- Q96FD2
Protein attributes for NOSIP Gene
- Size:
- 301 amino acids
- Molecular mass:
- 33172 Da
- Quaternary structure:
-
- Interacts with NOS1 and NOS3 (PubMed:11149895, PubMed:15548660). Interacts with PP2A holoenzyme, containing PPP2CA, PPP2CB, PPP2R1A and PPP2R2A subunits (By similarity).
Protein Expression for NOSIP Gene
Post-translational modifications for NOSIP Gene
Other Protein References for NOSIP Gene
Antibody Products
- Novus Biologicals Antibodies for NOSIP
-
Abcam antibodies for NOSIP
-
Cloud-Clone Corp. Antibodies for NOSIP
- Invitrogen Antibodies for NOSIP
- antibodies-online Antibodies for NOSIP: See all 38
- GeneTex NOSIP antibody for NOSIP
-
St John's Laboratory Antibodies for NOSIP
-
Santa Cruz Biotechnology (SCBT) Antibodies for NOSIP
Protein Products
-
OriGene Purified Proteins for NOSIP
- Search Origene for MassSpec and Protein Over-expression Lysates for NOSIP
- Origene Custom Protein Services for NOSIP
-
Cloud-Clone Corp. Proteins for NOSIP
- antibodies-online Proteins for NOSIP: See all 11
- Search antibodies-online for peptides
- Search GeneTex for Proteins for NOSIP
-
Abcam proteins for NOSIP
No data available for DME Specific Peptides for NOSIP Gene
Domains & Families for NOSIP Gene
Protein Domains for NOSIP Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NOSIP Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y314UniProtKB/Swiss-Prot:
NOSIP_HUMAN :- The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.
- Belongs to the NOSIP family.
- Domain:
-
- The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.
- Family:
-
- Belongs to the NOSIP family.
No data available for Gene Families for NOSIP Gene
Function for NOSIP Gene
Molecular function for NOSIP Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
Enzyme Numbers (IUBMB) for NOSIP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 11149895 |
| GO:0016874 | ligase activity | IEA | -- |
| GO:0044822 | poly(A) RNA binding | IDA | 22658674 |
| GO:0061630 | ubiquitin protein ligase activity | IBA | -- |
Phenotypes for NOSIP Gene
- GenomeRNAi human phenotypes for NOSIP:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for NOSIP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NOSIP gene
- Search ViGene Biosciences for NOSIP
CRISPR Products
-
OriGene CRISPR knockouts for NOSIP
- GenScript: Design CRISPR guide RNA sequences for NOSIP
miRNA for NOSIP Gene
- miRTarBase miRNAs that target NOSIP
miRNA Products
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Clone Products
- Sino Biological Human cDNA Clone for NOSIP
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NOSIP
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOSIP
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for NOSIP
-
ViGene Biosciences adenoviral particle packaged cDNA for NOSIP gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NOSIP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NOSIP gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NOSIP Gene
Localization for NOSIP Gene
Subcellular locations from UniProtKB/Swiss-Prot for NOSIP Gene
- Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| golgi apparatus | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005634 | nucleus | IDA | 15548660 |
| GO:0005737 | cytoplasm | IEA,IDA | 15548660 |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for NOSIP Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | eNOS activation and regulation | ||
| 2 | Nanog in Mammalian ESC Pluripotency |
.48
|
|
| 3 | Metabolism |
.37
|
|
Pathways by source for NOSIP Gene
4 Reactome pathways for NOSIP Gene
1 Qiagen pathway for NOSIP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA,IBA | -- |
| GO:0043086 | negative regulation of catalytic activity | IDA | 11149895 |
| GO:0050999 | regulation of nitric-oxide synthase activity | IEA,TAS | -- |
| GO:0051001 | negative regulation of nitric-oxide synthase activity | IDA | 11149895 |
No data available for SIGNOR curated interactions for NOSIP Gene
Transcripts for NOSIP Gene
mRNA/cDNA for NOSIP Gene
- (8) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (372) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NOSIP Gene
CRISPR Products
-
OriGene CRISPR knockouts for NOSIP
- GenScript: Design CRISPR guide RNA sequences for NOSIP
miRNA Products
- Search ViGene Biosciences for NOSIP
Clone Products
- Sino Biological Human cDNA Clone for NOSIP
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NOSIP
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOSIP
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - |
Expression for NOSIP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- T Helper Cells Peripheral Blood
- T-Cytotoxic Cells Peripheral Blood
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for NOSIP Gene
This gene is overexpressed in Whole Blood (x4.3).
This gene is overexpressed in Breast (43.4) and Lymph node (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NOSIP Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of NOSIP Gene:
NOSIPSOURCE GeneReport for Unigene cluster for NOSIP Gene:
Hs.7236mRNA Expression by UniProt/SwissProt for NOSIP Gene:
Q9Y314-NOSIP_HUMAN
Tissue specificity:
Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
Primer Products
-
OriGene qPCR primer pairs for NOSIP
-
OriGene qPCR primer pairs and template standards for NOSIP
Orthologs for NOSIP Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NOSIP 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | NOSIP 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | NOSIP 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Nosip 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Nosip 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | NOSIP 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | NOSIP 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | nosip 34 |
|
||
| MGC75989 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | nosip 34 35 |
|
||
| -- 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6179 36 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005654 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | R05G6.4 34 35 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G61620 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0279900 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for NOSIP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NOSIP Gene
No data available for Paralogs for NOSIP Gene
Variants for NOSIP Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10401626 | -- | 49,566,490(+) | caggc(A/G)gggtc | intron-variant | |
| rs10402160 | -- | 49,566,511(+) | gtcca(C/G)gttgg | intron-variant | |
| rs10409856 | -- | 49,559,783(+) | GCCCA(C/T)GTCCC | intron-variant | |
| rs10410923 | -- | 49,576,504(+) | cccag(A/G)aggtt | intron-variant, upstream-variant-2KB | |
| rs10412446 | -- | 49,564,251(+) | agttc(A/G)agtcc | intron-variant, upstream-variant-2KB, utr-variant-5-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1160655 | CNV | deletion | 26073780 |
| nsv469715 | CNV | gain+loss | 16826518 |
| nsv828578 | CNV | loss | 20364138 |
| nsv833862 | CNV | loss | 17160897 |
| nsv833863 | CNV | loss | 17160897 |
| nsv833864 | CNV | gain | 17160897 |
| nsv833865 | CNV | gain+loss | 17160897 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv9739 | CNV | gain+loss | 18304495 |
Residual Variation Intolerance Score:
26.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.42;
9.29% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for NOSIP Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NOSIP
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NOSIP Gene
Disorders for NOSIP Gene
Relevant External Links for NOSIP
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- NOSIP
No disorders were found for NOSIP Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NOSIP Gene
Publications for NOSIP Gene
- Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton. (PMID: 16135813) Schleicher M. … Oess S. (Mol. Cell. Biol. 2005) 3 4 22 64
- NOSIP, a novel modulator of endothelial nitric oxide synthase activity. (PMID: 11149895) Dedio J. … Mueller-Esterl W. (FASEB J. 2001) 2 3 4 64
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. (PMID: 15548660) Dreyer J. … Kuner R. (J. Neurosci. 2004) 3 4 64
Products for NOSIP Gene
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- Cloud-Clone Corp. Antibodies for NOSIP
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- antibodies-online Antibodies for NOSIP: See all 38
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- antibodies-online Proteins for NOSIP: See all 11
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- GeneTex NOSIP antibody for NOSIP
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- ViGene Biosciences adenoviral particle packaged cDNA for NOSIP gene
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- Horizon Cell Lines for NOSIP
- Cyagen custom Knockout/knockin (KOKI) mouse models for NOSIP
- VectorBuilder custom plasmid, inducible vectors for NOSIP
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOSIP
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for NOSIP Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
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