Aliases for NOS2 Gene
Aliases for NOS2 Gene
External Ids for NOS2 Gene
- HGNC: 7873
- Entrez Gene: 4843
- Ensembl: ENSG00000007171
- OMIM: 163730
- UniProtKB: P35228
Previous HGNC Symbols for NOS2 Gene
- NOS2A
Previous GeneCards Identifiers for NOS2 Gene
- GC17M023108
- GC17M026083
- GC17M022290
Summaries for NOS2 Gene
-
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
GeneCards Summary for NOS2 Gene
NOS2 (Nitric Oxide Synthase 2) is a Protein Coding gene. Diseases associated with NOS2 include Malaria and Hypertension, Essential. Among its related pathways are Bacterial infections in CF airways and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and oxidoreductase activity. An important paralog of this gene is NOS1.
UniProtKB/Swiss-Prot for NOS2 Gene
-
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on Cys-247 implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).
Additional gene information for NOS2 Gene
- Monarch Initiative
- Search for NOS2 at DataMed
- Search for NOS2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOS2 Gene
Genomics for NOS2 Gene
GeneHancer (GH) Regulatory Elements for NOS2 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH17I027800 | Promoter/Enhancer | 1.2 | EPDnew ENCODE | 550.8 | +3.6 | 3629 | 1.1 | FOXA2 RXRA HLF MAX ZIC2 RAD21 FOXA1 RARA NFIL3 JUND | NOS2 SLC13A2 LGALS9 PIR36820 ENSG00000266202 | |
GH17I027805 | Enhancer | 1.1 | Ensembl ENCODE | 550.8 | -1.6 | -1557 | 1.7 | HDGF ELF3 ATF1 RB1 SIN3A BMI1 IRF4 RAD21 RFX5 ZNF335 | NOS2 LYRM9 ENSG00000266527 ENSG00000266202 | |
GH17I027803 | Enhancer | 0.4 | ENCODE | 550.8 | +0.7 | 731 | 0.2 | GATA3 ZNF366 ZNF512 | NOS2 PIR36820 ENSG00000266202 | |
GH17I027888 | Enhancer | 1 | Ensembl ENCODE | 60 | -84.8 | -84776 | 2.1 | HDGF CLOCK NFIB NEUROD1 SIN3A THRB IKZF2 RUNX3 USF2 ZNF592 | NOS2 ENSG00000266202 GC17P027886 LYRM9 | |
GH17I027892 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE | 26.5 | -89.0 | -89047 | 2 | PKNOX1 SMAD1 ATF1 SIN3A ZNF143 KLF7 ATF7 REST ZNF592 KAT8 | ENSG00000266202 GC17M027891 LYRM9 NOS2 |
- Top Transcription factor binding sites by QIAGEN in the NOS2 gene promoter:
Regulatory Element Products
Genomic Locations for NOS2 Gene
- chr17:27,756,766-27,804,341
- (GRCh38/hg38)
- Size:
- 47,576 bases
- Orientation:
- Minus strand
- chr17:26,083,792-26,127,555
- (GRCh37/hg19)
Genomic View for NOS2 Gene
- Cytogenetic band:
-
- 17q11.2 by Ensembl
- 17q11.2 by Entrez Gene
- 17q11.2 by HGNC


RefSeq DNA sequence for NOS2 Gene
Proteins for NOS2 Gene
-
Protein details for NOS2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P35228-NOS2_HUMAN
- Recommended name:
- Nitric oxide synthase, inducible
- Protein Accession:
- P35228
- A1L3U5
- B7ZLY2
- O60757
- O94994
- Q16263
- Q16692
- Q4TTS5
- Q9UD42
Protein attributes for NOS2 Gene
- Size:
- 1153 amino acids
- Molecular mass:
- 131117 Da
- Cofactor:
- Name=(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin; Xref=ChEBI:CHEBI:59560;
- Cofactor:
- Name=FAD; Xref=ChEBI:CHEBI:57692;
- Cofactor:
- Name=FMN; Xref=ChEBI:CHEBI:58210;
- Cofactor:
- Name=heme; Xref=ChEBI:CHEBI:30413;
- Quaternary structure:
-
- Homodimer. Binds SLC9A3R1. Interacts with GAPDH; induced by oxidatively-modified low-densitity lipoprotein (LDL(ox)). Interacts with S100A8 and S100A9 to form the iNOS-S100A8/9 transnitrosylase complex.
Three dimensional structures from OCA and Proteopedia for NOS2 Gene
Protein Expression for NOS2 Gene
Selected DME Specific Peptides for NOS2 Gene
- P35228:
-
- VLEEFPS
- YSRLPGKPK
- SRQNLQSP
- RGGCPADW
- EEQVEDYFFQLK
- GWYMGTE
- LQVFDAR
- SFKEAKIEE
- EFTQLCIDLGWKP
- GPLHHGVCSTW
- AWRNAPRC
- DGKHDFR
- GDPANVE
- PFNGWYM
- VEINIAVL
- FEIPPDLVLEV
- RSAITVFPQR
- ELLPQAIEF
- KSLTRGPRDKPTP
- VTKEIETTGTY
- VVTSTFGNGD
- WKTHVWQDE
- CGDVRMARDVA
- FRYAVFGLGSSMYP
- EVGRRMGLE
- FLLSQLPILKPR
- FCAFAHDID
- LDITTPP
- EMFEHICRH
- GNIRSAIT
- DHHSAAESFMK
- MTLVFGCR
- QLIRYAGY
- DTLHHKA
- ATETGKS
- RQRLEALCQPSEY
- EIHLTVA
- QALTYFLDIT
- AVLHSFQKQNVTIMDHH
- LKWYALP
- TPVFHQEM
- APFRSFWQQR
- MEHPKYEWF
Post-translational modifications for NOS2 Gene
Other Protein References for NOS2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for NOS2 (iNOS)
- Novus Biologicals Antibodies for NOS2
-
Abcam antibodies for NOS2
-
Cloud-Clone Corp. Antibodies for NOS2
- Invitrogen Antibodies for NOS2
- antibodies-online: Search results for 326 available NOS2 Antibodies ranked by validation data
- Compare Top NOS2 Antibodies
-
Recommended
- 195 WB Antibodies (anti-human)
- 27 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 3 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IF/ICC Antibody (anti-human)
- 118 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IHC (p) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 3 FACS Antibodies (anti-mouse)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 5 IHC (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 195 WB Antibodies (anti-human)
- 27 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 3 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IF/ICC Antibody (anti-human)
- 118 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IHC (p) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 3 FACS Antibodies (anti-mouse)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 5 IHC (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- GeneTex NOS2 antibody for NOS2
-
Santa Cruz Biotechnology (SCBT) Antibodies for NOS2
Protein Products
-
OriGene Purified Proteins for NOS2
- Search Origene for MassSpec and Protein Over-expression Lysates for NOS2
- Origene Custom Protein Services for NOS2
-
Cloud-Clone Corp. Proteins for NOS2
- Search GeneTex for Proteins for NOS2
-
Abcam proteins for NOS2
Assay Products
- antibodies-online: Search results for 79 available NOS2 Elisa Kits ranked by validation data
- Compare Top NOS2 Elisa Kits
-
Recommended
- 3 Chicken ELISA Kits
- 2 Cow (Bovine) ELISA Kits
- 7 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 2 Guinea Pig ELISA Kits
- 20 Human ELISA Kits
- 3 Monkey ELISA Kits
- 13 Mouse (Murine) ELISA Kits
- 4 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 3 Chicken ELISA Kits
- 2 Cow (Bovine) ELISA Kits
- 7 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 2 Guinea Pig ELISA Kits
- 20 Human ELISA Kits
- 3 Monkey ELISA Kits
- 13 Mouse (Murine) ELISA Kits
- 4 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
Domains & Families for NOS2 Gene
Gene Families for NOS2 Gene
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Enzymes
- FDA approved drug targets
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for NOS2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NOS2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P35228- Family:
-
- Belongs to the NOS family.
Function for NOS2 Gene
Molecular function for NOS2 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- 2 L-arginine + 3 NADPH + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H(2)O.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Regulated by calcium/calmodulin. Aspirin inhibits expression and function of this enzyme and effects may be exerted at the level of translational/post-translational modification and directly on the catalytic activity (By similarity).
- UniProtKB/Swiss-Prot Function:
- Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on Cys-247 implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).
- UniProtKB/Swiss-Prot Induction:
- By endotoxins and cytokines. Induced by IFNG/IFN-gamma acting synergistically with bacterial lipopolysaccharides (LPS), TNF or IL1B/interleukin-1 beta (PubMed:7528267). Down-regulated by zinc due to inhibition of NF-kappa-B transactivation activity (PubMed:25180171). By oxidatively-modified low-densitity lipoprotein (LDL(ox)) (PubMed:25417112).
Enzyme Numbers (IUBMB) for NOS2 Gene
Phenotypes From GWAS Catalog for NOS2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003958 | NADPH-hemoprotein reductase activity | IBA | -- |
GO:0004517 | nitric-oxide synthase activity | TAS | -- |
GO:0005102 | receptor binding | IPI | 20178365 |
GO:0005506 | iron ion binding | IEA | -- |
GO:0005515 | protein binding | IPI | 12855682 |
Phenotypes for NOS2 Gene
- MGI mutant phenotypes for NOS2:
-
inferred from 3 alleles
- nervous system phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- muscle phenotype
- cardiovascular system phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- behavior/neurological phenotype
- growth/size/body region phenotype
- neoplasm
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- vision/eye phenotype
- integument phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- craniofacial phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for NOS2:
-
- Increased viability
- Increased gamma-H2AX phosphorylation
- shRNA abundance <= 50%
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Decreased shRNA abundance
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased viability after Chlamydia trachomatis serovar L2 infection and TNF-alpha/CHX stimulation
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NOS2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NOS2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NOS2 gene
- Search ViGene Biosciences for NOS2
CRISPR Products
-
OriGene CRISPR knockouts for NOS2
- genomics-online: gRNA clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
-
Recommended
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- Applied Biological Materials CRISPR for NOS2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NOS2
- GenScript: Design CRISPR guide RNA sequences for NOS2
miRNA for NOS2 Gene
- miRTarBase miRNAs that target NOS2
miRNA Products
- Search ViGene Biosciences for NOS2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NOS2
- Browse OriGene Inhibitory RNA Products For NOS2
- genomics-online: shRNA clones - Search results for 84 available NOS gene related products
- Overview of 84 available NOS gene related products
-
Recommended
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
-
ViGene Biosciences ready-to-package AAV shRNAs for NOS2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NOS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOS2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
-
Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- orf clones - Search results for 84 available NOS gene related products
- Overview of 84 available NOS gene related products
-
Recommended
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- Applied Biological Materials Clones for NOS2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for NOS2
-
ViGene Biosciences adenoviral particle packaged cDNA for NOS2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NOS2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NOS2 gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NOS2 Gene
Localization for NOS2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005622 | intracellular | IDA | 7544003 |
GO:0005634 | nucleus | ISS | -- |
GO:0005737 | cytoplasm | IDA | 9916929 |
GO:0005777 | peroxisome | IDA | 12085352 |
GO:0005829 | cytosol | TAS,IMP | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for NOS2 Gene
Pathways & Interactions for NOS2 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Arginine biosynthesis | ||
2 | Toxoplasmosis |
.35
|
.35
|
3 | G-Beta Gamma Signaling |
.44
|
.37
|
4 | PEDF Induced Signaling | ||
5 | Toll Comparative Pathway |
.34
|
Pathways by source for NOS2 Gene
15 BioSystems pathways for NOS2 Gene
9 Reactome pathways for NOS2 Gene
3 PharmGKB pathways for NOS2 Gene
17 KEGG pathways for NOS2 Gene
11 GeneGo (Thomson Reuters) pathways for NOS2 Gene
10 Qiagen pathways for NOS2 Gene
Interacting Proteins for NOS2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001666 | response to hypoxia | IEA | -- |
GO:0001912 | positive regulation of leukocyte mediated cytotoxicity | TAS | 10450191 |
GO:0002227 | innate immune response in mucosa | NAS | 18390757 |
GO:0006527 | arginine catabolic process | IDA | 7504305 |
GO:0006801 | superoxide metabolic process | ISS | -- |
Drugs & Compounds for NOS2 Gene
(131) Drugs for NOS2 Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Dexamethasone | Approved, Investigational, Vet_approved | Pharma | Agonist, Target, negative modulator | 2314 | ||
Citrulline | Approved, Investigational | Nutra | Full agonist, Agonist, Target | 0 | ||
Miconazole | Approved, Investigational, Vet_approved | Pharma | Antagonist, Pore Blocker, Target, inhibitor | 3838 | ||
L-Arginine | Approved | Nutra | Full agonist, Agonist, Target | 0 | ||
Nitric Oxide | Approved | Pharma | 643 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
nadph |
|
53-57-6 | ||||
Hydrogen Ion |
|
|
||||
N-(o)-Hydroxyarginine |
|
|
||||
NADP |
|
53-59-8 |
|
(5) Tocris Compounds for NOS2 Gene
Compound | Action | Cas Number |
---|---|---|
(S)-Methylisothiourea sulfate | Highly selective iNOS inhibitor | 867-44-7 |
Aminoguanidine hydrochloride | Irreversible iNOS inhibitor | 1937-19-5 |
AMT hydrochloride | Potent, selective iNOS inhibitor | 21463-31-0 |
EIT hydrobromide | Selective iNOS inhibitor, acts arginine binding site | 1071-37-0 |
S-Isopropylisothiourea hydrobromide | iNOS inhibitor, acts at arginine binding site | 4269-97-0 |
(23) ApexBio Compounds for NOS2 Gene
Compound | Action | Cas Number |
---|---|---|
(S)-Methylisothiourea sulfate | 867-44-7 | |
1400W dihydrochloride | INOS inhibitor,potent and highly selective | 214358-33-5 |
2,4-Diamino-6-hydroxypyrimidine | 1956-06-4 | |
2-Iminopiperidine hydrochloride | 16011-96-4 | |
3-Bromo-7-nitroindazole | 74209-34-0 | |
7-NINA | 161467-34-1 | |
7-Nitroindazole | 2942-42-9 | |
Aminoguanidine hydrochloride | 1937-19-5 | |
AMT hydrochloride | 21463-31-0 | |
AR-C 102222 | 253771-21-0 | |
ARL 17477 dihydrochloride | Selective nNOS inhibitor | 866914-87-6 |
BYK 191023 dihydrochloride | INOS inhibitor,potent and selective | 1216722-25-6 |
Carboxy-PTIO, potassium salt | 148819-94-7 | |
DMPO | 3317-61-1 | |
EIT hydrobromide | 1071-37-0 | |
L-Canavanine sulfate | 2219-31-0 | |
L-NIL hydrochloride | 150403-89-7 | |
L-NMMA acetate | 53308-83-1 | |
Nω-Propyl-L-arginine hydrochloride | 137361-05-8 | |
ODQ | 41443-28-1 | |
Saikosaponin A | COX-2 and iNOS inhibitor | 20736-09-8 |
S-Isopropylisothiourea hydrobromide | 4269-97-0 | |
TRIM | 25371-96-4 |
Transcripts for NOS2 Gene
mRNA/cDNA for NOS2 Gene
- (6) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (75) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NOS2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for NOS2
- genomics-online: gRNA clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
-
Recommended
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- Applied Biological Materials CRISPR for NOS2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NOS2
- GenScript: Design CRISPR guide RNA sequences for NOS2
miRNA Products
- Search ViGene Biosciences for NOS2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NOS2
- Browse OriGene Inhibitory RNA Products For NOS2
- genomics-online: shRNA clones - Search results for 84 available NOS gene related products
- Overview of 84 available NOS gene related products
-
Recommended
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
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- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
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- pLenti-U6-sgRNA-PGK-Neo
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- pPB-His-MBP
- pPB-N-His
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- pLenti-C-mGFP
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- pCMV6-Entry
- pCMV6-XL4
-
ViGene Biosciences ready-to-package AAV shRNAs for NOS2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NOS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOS2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
-
Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- orf clones - Search results for 84 available NOS gene related products
- Overview of 84 available NOS gene related products
-
Recommended
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- Applied Biological Materials Clones for NOS2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - |
ExUns: | 26 | ^ | 27 | ^ | 28 |
---|---|---|---|---|---|
SP1: | |||||
SP2: | |||||
SP3: |
Expression for NOS2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Ectoderm (Nervous System)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Colon (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for NOS2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NOS2 Gene
NURSA nuclear receptor signaling pathways regulating expression of NOS2 Gene:
NOS2SOURCE GeneReport for Unigene cluster for NOS2 Gene:
Hs.709191mRNA Expression by UniProt/SwissProt for NOS2 Gene:
P35228-NOS2_HUMANEvidence on tissue expression from TISSUES for NOS2 Gene
- Kidney(4.5)
- Liver(4.5)
- Lung(4.5)
- Eye(4.2)
- Heart(2.9)
- Muscle(2.9)
- Blood(2.8)
- Nervous system(2.8)
- Intestine(2.5)
Primer Products
-
OriGene qPCR primer pairs for NOS2
- genomics-online: primer clones - Search results for 84 available NOS gene related products
- Overview of 84 available NOS gene related products
-
Recommended
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
- pGFP-V-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pRS
- pPB-His-MBP
- pPB-N-His
- pPB-His-GST
- pPB-C-His
- pRFP-C-RS
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pCMV6-XL4
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NOS2 Gene
Orthologs for NOS2 Gene
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | NOS2 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | NOS2 33 |
|
||
INOS 34 |
|
OneToOne | |||
dog (Canis familiaris) |
Mammalia | NOS2 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | LOC497963 33 |
|
||
mouse (Mus musculus) |
Mammalia | Nos2 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | NOS2 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | NOS2 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | NOS2 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | NOS2 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | nos2 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | nos2b 33 34 |
|
||
nos2a 34 |
|
OneToMany | |||
fruit fly (Drosophila melanogaster) |
Insecta | Nos 34 |
|
OneToMany | |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NCP1 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5751 34 |
|
OneToMany |
- Species where no ortholog for NOS2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for NOS2 Gene
(2) SIMAP similar genes for NOS2 Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for NOS2 Gene
- PGOHUM00000292259
- PGOHUM00000292262
- PGOHUM00000292556
- PGOHUM00000292559
- PGOHUM00000293978
- PGOHUM00000294027
- PGOHUM00000294032
- PGOHUM00000294076
- PGOHUM00000294082
- PGOHUM00000294094
- PGOHUM00000294100
- PGOHUM00000294179
- PGOHUM00000294283
- PGOHUM00000294320
- PGOHUM00000294404
- PGOHUM00000294410
- PGOHUM00000294416
- PGOHUM00000297417
- PGOHUM00000298122
- PGOHUM00000288138
- PGOHUM00000288146
- PGOHUM00000288150
- PGOHUM00000288252
- PGOHUM00000288259
- PGOHUM00000288271
- PGOHUM00000288283
- PGOHUM00000288289
Variants for NOS2 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for NOS2 Gene
- NOS2_HUMAN-P35228
- Note=Genetic variations in NOS2 are involved in resistance to malaria [MIM:611162].
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs2301368 | association, repeat number of microsatellite | 27,803,092(-) | G/A | genic_upstream_transcript_variant, intron_variant | |
rs372421318 | association, repeat number of microsatellite | 27,803,092(-) | G/ | genic_upstream_transcript_variant, intron_variant | |
rs769900089 | A breast cancer sample | 27,767,837(-) | C/A/T | coding_sequence_variant, missense_variant | |
rs1000084421 | -- | 27,793,441(-) | A/G | intron_variant | |
rs1000160472 | -- | 27,798,593(-) | C/A | genic_upstream_transcript_variant, intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2715781 | CNV | deletion | 23290073 |
esv2758683 | CNV | gain | 17122850 |
esv28579 | CNV | gain | 19812545 |
esv3640299 | OTHER | inversion | 21293372 |
nsv471953 | CNV | novel sequence insertion | 20440878 |
nsv9533 | CNV | gain | 18304495 |
nsv960452 | CNV | duplication | 23825009 |
nsv962299 | CNV | duplication | 23825009 |
Additional Variant Information for NOS2 Gene
Disorders for NOS2 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
malaria |
|
|
hypertension, essential |
|
|
borderline leprosy |
|
|
platelet membrane fluidity |
|
|
idiopathic achalasia |
|
|
Additional Disease Information for NOS2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for NOS2 Gene
Publications for NOS2 Gene
- Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. (PMID: 7682706) Geller DA … Billiar TR (Proceedings of the National Academy of Sciences of the United States of America 1993) 2 3 4 22 58
- Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients. (PMID: 19242068) Bohanec Grabar P … Dolzan V (Disease markers 2009) 3 22 44 58
- A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. (PMID: 12433515) Hobbs MR … Weinberg JB (Lancet (London, England) 2002) 3 4 44 58
- Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase. (PMID: 10409685) Li H … Poulos TL (The Journal of biological chemistry 1999) 3 4 22 58
- Dedifferentiated human ventricular cardiac myocytes express inducible nitric oxide synthase mRNA but not protein in response to IL-1, TNF, IFNgamma, and LPS. (PMID: 9160867) Luss H … Billiar TR (Journal of molecular and cellular cardiology 1997) 3 4 22 58
Products for NOS2 Gene
- R&D Systems Antibodies for NOS2 (iNOS)
- Browse R&D Systems for Human Recombinant Proteins
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- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for NOS2
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- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- Cloud-Clone Corp. Antibodies for NOS2
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- Browse Knockouts at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for NOS2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for NOS2
- Cyagen custom Knockout/knockin (KOKI) mouse models for NOS2
- VectorBuilder custom plasmid, inducible vectors for NOS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NOS2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 326 available NOS2 Antibodies ranked by validation data
- Compare Top NOS2 Antibodies
- Recommended
- 195 WB Antibodies (anti-human)
- 27 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 3 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IF/ICC Antibody (anti-human)
- 118 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IHC (p) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 3 FACS Antibodies (anti-mouse)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 5 IHC (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 195 WB Antibodies (anti-human)
- 27 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 7 IHC Antibodies (anti-human)
- 3 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 1 IF Antibody (anti-human)
- 1 IF/ICC Antibody (anti-human)
- 118 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 12 IHC (p) Antibodies (anti-mouse)
- 9 IHC Antibodies (anti-mouse)
- 3 FACS Antibodies (anti-mouse)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 5 IHC (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- antibodies-online: Search results for 79 available NOS2 Elisa Kits ranked by validation data
- Compare Top NOS2 Elisa Kits
- Recommended
- 3 Chicken ELISA Kits
- 2 Cow (Bovine) ELISA Kits
- 7 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 2 Guinea Pig ELISA Kits
- 20 Human ELISA Kits
- 3 Monkey ELISA Kits
- 13 Mouse (Murine) ELISA Kits
- 4 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 3 Chicken ELISA Kits
- 2 Cow (Bovine) ELISA Kits
- 7 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 2 Guinea Pig ELISA Kits
- 20 Human ELISA Kits
- 3 Monkey ELISA Kits
- 13 Mouse (Murine) ELISA Kits
- 4 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- antibodies-online: Search results for 22 available NOS2 Proteins ranked by validation data
- Compare Top NOS2 Proteins
- GeneTex NOS2 antibody for NOS2
- Search GeneTex for Proteins for NOS2
- ViGene Biosciences adenoviral particle packaged cDNA for NOS2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for NOS2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for NOS2 gene
- Search ViGene Biosciences for NOS2
- Santa Cruz Biotechnology (SCBT) Antibodies for NOS2
- Search Santa Cruz Biotechnology (SCBT) for NOS2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NOS2
- Horizon Cell Lines for NOS2
- genomics-online: cdna clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
- Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- orf clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
- Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- genomics-online: gRNA clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
- Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- genomics-online: primer clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
- Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- genomics-online: shRNA clones - Search results for 84 available NOS2 gene related products
- Overview of 84 available NOS2 gene related products
- Recommended
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
- pCMV6-XL4
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pRFP-C-RS
- pPB-C-His
- pPB-His-GST
- pPB-N-His
- pPB-His-MBP
- pRS
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pGFP-V-RS
Sources for NOS2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew