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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NOS2 Gene

protein-coding   GIFtS: 70
GCID: GC17M026083

Nitric Oxide Synthase 2, Inducible

(Previous names: nitric oxide synthase 2A (inducible, hepatocytes))
(Previous symbol: NOS2A)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nitric Oxide Synthase 2, Inducible1 2     NOS Type II2 3
NOS2A1 2 3 5     EC 1.14.13.393 8
Nitric Oxide Synthase 2A (Inducible, Hepatocytes)1 2     INOS2
Hepatocyte NOS2 3     NOS2
Inducible NO Synthase2 3     Nitric Oxide Synthase, Inducible2
Inducible NOS2 3     Nitric Oxide Synthase, Macrophage2
Peptidyl-Cysteine S-Nitrosylase NOS22 3     NOS, Type II2
HEP-NOS2 3     iNOS3

External Ids:    HGNC: 78731   Entrez Gene: 48432   Ensembl: ENSG000000071717   OMIM: 1637305   UniProtKB: P352283   

Export aliases for NOS2 gene to outside databases

Previous GC identifers: GC17M023108 GC17M022290


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NOS2 Gene:
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including
neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which
is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three
related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. (provided by RefSeq,
Jul 2008)

GeneCards Summary for NOS2 Gene: 
NOS2 (nitric oxide synthase 2, inducible) is a protein-coding gene. Diseases associated with NOS2 include virilizing ovarian tumor, and pityriasis lichenoides, and among its related super-pathways are Immune response IL-12-induced IFN-gamma production and Bacterial infections in CF airways. GO annotations related to this gene include calmodulin binding and protein homodimerization activity. An important paralog of this gene is NOS3.

UniProtKB/Swiss-Prot: NOS2_HUMAN, P35228
Function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In
macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates
cysteine S-nitrosylation of cytoplasmic target proteins such COX2

summary for NOS2 Gene:
Inducible nitric oxide synthase (iNOS), along with neuronal nitric oxide synthase (nNOS) and endothelial
nitric oxide synthase (eNOS), catalyze the generation of nitric oxide and L-citrulline from L-arginine and
molecular oxygen. It displays high affinity for Ca2+/calmodulin, thus appears to be constitutively active.
Tetrahydrobiopterin, flavin adenine dinucleotide, flavin mononucleotide and NADPH co-factors are required
for catalytic activity. iNOS gene expression is regulated by various pathways including NF-kappaB, IFN-gamma
(signaling through the JAK-STAT cascade) and HIF-1, which induce expression, and TGF-beta and interleukins
-4, -10 and -13, which inhibit expression. Post-translational regulation occurs by prevention of iNOS
homodimerization by NAP110. iNOS has roles in the innate immune system and displays antibacterial, antiviral
and antifungal activity. The human gene encoding iNOS is localized to chromosome 17q11.2-q12.

Gene Wiki entry for NOS2 (Nitric oxide synthase 2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NOS2 gene promoter:
         p300   MyoD   IRF-1   HNF-3beta   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): NOS2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NOS2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2-q12   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2-q12

NOS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOS2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M026083:  view genomic region     (about GC identifiers)

Start:
26,083,792 bp from pter      End:
26,127,555 bp from pter
Size:
43,764 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NOS2_HUMAN, P35228 (See protein sequence)
Recommended Name: Nitric oxide synthase, inducible  
Size: 1153 amino acids; 131117 Da
Cofactor: Heme group (By similarity)
Cofactor: Binds 1 FAD (By similarity)
Cofactor: Binds 1 FMN (By similarity)
Cofactor: Tetrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme (By similarity)
Subunit: Homodimer. Binds SLC9A3R1
6/7 PDB 3D structures from and Proteopedia for NOS2 (see all 7):
1NSI (3D)        2LL6 (3D)        2NSI (3D)        3E7G (3D)        3EJ8 (3D)        3HR4 (3D)    
Secondary accessions: A1L3U5 B7ZLY2 O60757 O94994 Q16263 Q16692 Q4TTS5 Q9UD42
Alternative splicing: 2 isoforms:  P35228-1   P35228-2   

Explore the universe of human proteins at neXtProt for NOS2: NX_P35228

Explore proteomics data for NOS2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P35228

  • 4/43 DME Specific Peptides for NOS2 (P35228) (see all 43)
     VLEEFPS  GWYMGTE  LDITTPP  LQVFDAR 

    NOS2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NOS2 Protein Expression
    REFSEQ proteins: NP_000616.3  
    ENSEMBL proteins: 
     ENSP00000327251  
    Reactome Protein details: P35228
    Human Recombinant Protein Products for NOS2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for NOS2
    OriGene Purified Protein for NOS2
    OriGene Protein Over-expression Lysate for NOS2
    OriGene MassSpec for NOS2 
    OriGene Custom Protein Services for NOS2
    GenScript Custom Purified and Recombinant Proteins Services for NOS2
    Novus Biologicals NOS2 Protein
    Novus Biologicals NOS2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NOS2 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA7544003
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm IDA12085352
    GO:0005777peroxisome IDA12085352
    GO:0005829cytosol TAS--

    NOS2 for ontologies           About GeneDecksing



    NOS2 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of NOS2
    R&D Systems Antibodies for NOS2 (iNOS)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NOS2
    GenScript Custom Superior Antibodies Services for NOS2
    Novus Biologicals NOS2 Antibodies
    Abcam antibodies for NOS2
    Cloud-Clone Corp. Antibodies for NOS2 
    ThermoFisher Antibody for NOS2
    LSBio Antibodies in human, mouse, rat for NOS2 

    Assay Products for NOS2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NOS2
    R&D Systems ELISAs for NOS2 (iNOS)
    GenScript Custom Assay Services for NOS2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NOS2 
    Cloud-Clone Corp. CLIAs for NOS2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: Inducible NOS 
    Nitric oxide synthases

    5/11 InterPro protein domains (see all 11):
     IPR026009 NOS
     IPR017927 Fd_Rdtase_FAD-bd
     IPR001094 Flavdoxin
     IPR008254 Flavodoxin/NO_synth
     IPR001433 OxRdtase_FAD/NAD-bd

    Graphical View of Domain Structure for InterPro Entry P35228

    ProtoNet protein and cluster: P35228

    5/6 Blocks protein domains (see all 6):
    IPB001094 Flavodoxin signature
    IPB001433 Oxidoreductase FAD/NAD(P)-binding
    IPB001709 Flavoprotein pyridine nucleotide cytochrome reductase signature
    IPB003097 FAD-binding
    IPB004030 Nitric oxide synthase


    UniProtKB/Swiss-Prot: NOS2_HUMAN, P35228
    Similarity: Belongs to the NOS family
    Similarity: Contains 1 FAD-binding FR-type domain
    Similarity: Contains 1 flavodoxin-like domain


    NOS2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NOS2_HUMAN, P35228
    Function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In
    macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates
    cysteine S-nitrosylation of cytoplasmic target proteins such COX2
    Catalytic activity: 2 L-arginine + 3 NADPH + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H(2)O
    Enzyme regulation: Regulated by calcium/calmodulin. Aspirin inhibits expression and function of this enzyme and
    effects may be exerted at the level of translational/post-translational modification and directly on the
    catalytic activity (By similarity)
    Induction: By endotoxins and cytokines. Induced by IFNG/IFN-gamma acting synergistically with bacterial
    lipopolysaccharides (LPS), TNF or IL1B/interleukin-1 beta

         Enzyme Number (IUBMB): EC 1.14.13.391 2

         Gene Ontology (GO): 5/14 molecular function terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003958NADPH-hemoprotein reductase activity IBA--
    GO:0004517nitric-oxide synthase activity IDA7504305
    GO:0005102receptor binding IPI--
    GO:0005506iron ion binding IEA--
    GO:0005515protein binding IPI12855682
         
    NOS2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NOS2:
     Decreased viability after Chla  Increased gamma-H2AX phosphory 

         15/23 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Nos2) (see all 23):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  craniofacial 
     digestive/alimentary  endocrine/exocrine gland  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  integument  liver/biliary system  mortality/aging  muscle 

    NOS2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for NOS2: Nos2tm1Mrl Nos2tm1Lau Nos2tm1Liew

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NOS2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NOS2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOS2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOS2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOS2
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NOS2:
    hsa-miR-485-3p hsa-miR-323-5p
    SwitchGear 3'UTR luciferase reporter plasmidNOS2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NOS2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOS2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NOS2
    Sirion Biotech Customized adenovirus for overexpression of NOS2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NOS2 (see all 7)
    OriGene ORF clones in mouse, rat for NOS2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOS2 (NM_000625)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOS2
    Sirion Biotech Customized lentivirus for stable overexpression of NOS2 
                         Customized lentivirus expression plasmids for stable overexpression of NOS2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NOS2
    Search LifeMap BioReagents cell lines for NOS2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOS2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NOS2 About   (see all 37)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Immune response IL-12-induced IFN-gamma production
    Immune response IL-12-induced IFN-gamma production0.88
    IL12-mediated signaling events0.33
    2Immune response Bacterial infections in normal airways
    Immune response Bacterial infections in normal airways0.78
    Bacterial infections in CF airways0.78
    3Nitric oxide stimulates guanylate cyclase
    Nitric oxide stimulates guanylate cyclase0.75
    Platelet homeostasis0.34
    4Insulin receptor recycling
    Latent infection of Homo sapiens with Mycobacterium tuberculosis0.64
    Phagosomal maturation (early endosomal stage)0.64
    5Toll Comparative Pathway
    Immune response MIF in innate immunity response0.46
    Immune response IL-1 signaling pathway0.41

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/6 EMD Millipore Pathways for NOS2 (see all 6)
        Immune response IL-12-induced IFN-gamma production
    G-protein signaling Rac2 regulation pathway
    Immune response MIF-mediated glucocorticoid regulation
    Immune response MIF in innate immunity response
    Immune response CCR3 signaling in eosinophils


    5/11 GeneGo (Thomson Reuters) Pathways for NOS2 (see all 11)
        Immune response MIF-mediated glucocorticoid regulation
    Immune response Bacterial infections in normal airways
    Immune response MIF in innate immunity response
    Development VEGF signaling via VEGFR2 - generic cascades
    Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)

    5/11 BioSystems Pathways for NOS2 (see all 11)
        Type II interferon signaling (IFNG)
    Spinal Cord Injury
    AGE/RAGE pathway
    Prolactin Signaling Pathway
    citrulline-nitric oxide cycle

    5/6        Reactome Pathways for NOS2 (see all 6)
        Hemostasis
    Phagosomal maturation (early endosomal stage)
    Latent infection of Homo sapiens with Mycobacterium tuberculosis
    Platelet homeostasis
    Nitric oxide stimulates guanylate cyclase

    2 PharmGKB Pathways for NOS2
        Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics
    Doxorubicin Pathway, Pharmacokinetics

    5/14         Kegg Pathways  (Kegg details for NOS2) (see all 14):
        Arginine and proline metabolism
    Metabolic pathways
    Calcium signaling pathway
    HIF-1 signaling pathway
    Peroxisome


    NOS2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NOS2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/60 Interacting proteins for NOS2 (P352283 ENSP000003272514) via UniProtKB, MINT, STRING, and/or I2D (see all 60)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM2P621583, ENSP000002722984I2D: score=1 STRING: ENSP00000272298
    CALM1P621583, ENSP000003494674I2D: score=1 STRING: ENSP00000349467
    CALM3P621583I2D: score=1 
    ACTN4O437073, ENSP000002526994I2D: score=4 STRING: ENSP00000252699
    RAC2P151533, ENSP000002490714I2D: score=4 STRING: ENSP00000249071
    About this table

    Gene Ontology (GO): 5/27 biological process terms (GO ID links to tree view) (see all 27):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEA--
    GO:0001912positive regulation of leukocyte mediated cytotoxicity TAS10450191
    GO:0002227innate immune response in mucosa NAS18390757
    GO:0006527arginine catabolic process IDA7504305
    GO:0006801superoxide metabolic process ISS--

    NOS2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NOS2 for compounds           About GeneDecksing

    EMD Millipore small molecules for NOS2:
    Small Molecule - inhibitor
    Enzo Life Sciences drugs & compounds for NOS2

    Compounds for NOS2 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    BYK 191023 dihydrochloridePotent and selective inhibitor of iNOS[608880-48-4]
    L-NIL hydrochlorideSelective iNOS inhibitor[150403-89-7]
    1400W dihydrochloride Potent, highly selective iNOS inhibitor [180001-34-7]
    AMT hydrochloride Potent, selective iNOS inhibitor [21463-31-0]
    (S)-Methylisothiourea sulfateHighly selective iNOS inhibitor[867-44-7]

    10 HMDB Compounds for NOS2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Citrulline(2S)-2-amino-5-(carbamoylamino)pentanoic acid (see all 55)372-75-8--
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    Flavin MononucleotideFMN (see all 19)146-17-8--
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    L-Arginine(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)74-79-3--
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    NADPH2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23)53-57-6--
    Nitric oxideMononitrogen monoxide (see all 9)10102-43-9--
    Tetrahydrobiopterin(1R,2S)-(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)-1,2-propandiol (see all 11)17528-72-2--

    10/40 DrugBank Compounds for NOS2 (see all 40)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Arginine(S)-2-Amino-5-guanidinovaleric acid (see all 4)74-79-3target--17513447 17340133 16778961 17362916 17363779
    L-Citrulline2-Amino-5-uredovaleric acid (see all 8)372-75-8target--12745988 10906994 11742852 10906995 10944418
    Aminoguanidine-- 79-17-4targetinhibitor17139284 11752352 17016423 10592235
    DexamethasoneDesametasone (see all 9)50-02-2targetnegative modulator17494951 17503181 11752352 17379310
    Miconazole-- 22916-47-8targetinhibitor7536941 7518297 7683652 9873034
    Triflusal-- --targetagonist9551715 19465361 16939630 10998082
    3-Bromo-7-Nitroindazole-- --target--17139284 17016423 10592235
    4r-Fluoro-N6-Ethanimidoyl-L-Lysine-- --target--17139284 17016423 10592235
    5-Nitroindazole-- --target--17139284 17016423 10592235
    6-Nitroindazole-- --target--17139284 17016423 10592235

    5 IUPHAR Ligands for NOS2 (Inducible NOS)    About this table 
    LigandTypeActionAffinityPubmed IDs
    1400W
    InhibitorInhibition8.29030556
    2-amino-4-methylpyridine
    InhibitorInhibition7.48937711
    PIBTU
    InhibitorInhibition7.37523409
    NIL
    InhibitorInhibition5.57525961
    aminoguanidine
    InhibitorInhibition5.51378415

    10/124 Novoseek inferred chemical compound relationships for NOS2 gene (see all 124)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nitric oxide 97.5 18892 11680730 (10), 11342896 (8), 16957516 (8), 18554637 (8) (see all 99)
    citrulline 87.5 279 20148434 (3), 20148433 (3), 8561501 (3), 7527657 (2) (see all 99)
    l-nmma 87.3 488 9503327 (4), 12810424 (3), 17724209 (3), 18090547 (3) (see all 99)
    arginine 86.4 1048 16245240 (5), 11275358 (5), 8639550 (5), 7664438 (4) (see all 99)
    peroxynitrite 86.2 233 11788351 (4), 9180331 (3), 10383909 (3), 9122229 (3) (see all 99)
    aminoguanidine 84.9 363 9538001 (5), 16553284 (4), 18790185 (4), 11062159 (3) (see all 99)
    adma 83.5 234 8743168 (5), 15325021 (4), 19682580 (4), 10802528 (3) (see all 99)
    tetrahydrobiopterin 79.4 94 15565652 (2), 14609340 (2), 16052472 (2), 16172396 (2) (see all 67)
    cgmp 78.8 303 18606420 (5), 10802528 (4), 11181408 (4), 8633049 (4) (see all 99)
    n(g)-nitro-l-arginine methyl ester 76.8 176 11891189 (2), 7684763 (1), 7673269 (1), 8991992 (1) (see all 99)

    Search CenterWatch for drugs/clinical trials and news about NOS2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NOS2 gene (2 alternative transcripts): 
    NM_000625.4  NM_153292.1  

    Unigene Cluster for NOS2:

    Nitric oxide synthase 2, inducible
    Hs.709191  [show with all ESTs]
    Unigene Representative Sequence: NM_000625
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000313735(uc002gzu.3 uc010wab.1 uc010crh.1)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOS2
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NOS2:
    hsa-miR-485-3p hsa-miR-323-5p
    SwitchGear 3'UTR luciferase reporter plasmidNOS2 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NOS2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOS2
    Clone
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    OriGene clones in human, mouse for NOS2 (see all 7)
    OriGene ORF clones in mouse, rat for NOS2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOS2 (NM_000625)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOS2
    Sirion Biotech Customized lentivirus for stable overexpression of NOS2 
                         Customized lentivirus expression plasmids for stable overexpression of NOS2 
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    OriGene qSTAR qPCR primer pairs in human, mouse for NOS2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NOS2
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOS2

    Additional mRNA sequence: 

    AB022318.1 AF068236.1 AK304252.1 BC130283.1 BC144126.1 D26525.1 L09210.1 L24553.1 
    S75615.1 S76479.1 U05810.1 U20141.1 U31511.1 X73029.1 

    2 DOTS entries:

    DT.412801  DT.95333286 

    24/75 AceView cDNA sequences (see all 75):

    NM_000625 L24553 AI991263 X73029 AI738789 CD609259 BE073577 S76479 
    BE073638 AI797675 S75615 BM834810 AW297448 U31511 AW449618 AI953734 
    AW445097 NM_153292 U20141 U05810 CD609228 BG099280 CD609248 AA877840 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NOS2    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^
    SP1:                    -                                                                                                                                       
    SP2:                    -                                                                                                                                       
    SP3:                                      -                                                                                                                     

    ExUns: 26 ^ 27 ^ 28
    SP1:                  
    SP2:                  
    SP3:                  


    ECgene alternative splicing isoforms for NOS2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NOS2 expression in normal human tissues (normalized intensities)      NOS2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTGCATTT
    NOS2 Expression
    About this image


    NOS2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+BMP4-induced 4D20.8 cells
             fetal cartilage   
     
     Bone (Muscoskeletal System)
             HyStem+BMP4-induced 4D20.8 cells
     
     Brain (Nervous System)
             N2/LSB induced-cells ( Generation of midbrain dopaminergic, forebrain and hypothalamic...
     
     Colon (Gastrointestinal Tract)

    See NOS2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NOS2

    SOURCE GeneReport for Unigene cluster: Hs.709191

    UniProtKB/Swiss-Prot: NOS2_HUMAN, P35228
    Tissue specificity: Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not
    expressed in the platelets

        SABiosciences Expression via Pathway-Focused PCR Arrays including NOS2 (see all 14): 
              Insulin Signaling Pathway in human mouse rat
              G-Protein-Coupled Receptor Signaling PathwayFinder in human mouse rat
              Oxidative Stress in human mouse rat
              Nitric Oxide Signaling Pathway in human mouse rat
              Skeletal Muscle: Myogenesis & Myopathy in human mouse rat

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    OriGene qSTAR qPCR primer pairs in human, mouse for NOS2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NOS2
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOS2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOS2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NOS2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nos21 , 5 nitric oxide synthase 2, inducible1, 5 82.4(n)1
    81.21(a)1
      11 (46.74 cM)5
    181261  NM_010927.31  NP_035057.11 
     789207875 
    chicken
    (Gallus gallus)
    Aves NOS21 nitric oxide synthase 2, inducible 68.43(n)
    70.46(a)
      395807  NM_204961.1  NP_990292.1 
    lizard
    (Anolis carolinensis)
    Reptilia NOS26
    nitric oxide synthase 2, inducible
    56(a)
    1 ↔ 1
    GL343729.1(116369-178014)
    zebrafish
    (Danio rerio)
    Actinopterygii nos2b1 nitric oxide synthase 2b, inducible 61.56(n)
    60.63(a)
      563654  NM_001113501.1  NP_001106973.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nos6
    CG148826
    --
    38(a)
    24(a)
    1 ↔ many
    possible ortholog
    2L(10804269-10838448)
    3R(12268966-12270526)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NCP16
    NADP-cytochrome P450 reductase; involved in ergost...
    23(a)
    1 → many
    VIII(190543-192618)


    ENSEMBL Gene Tree for NOS2 (if available)
    TreeFam Gene Tree for NOS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NOS2 gene
    NOS32  POR2  MTRR2  NOS12  
    2 SIMAP similar genes for NOS2 using alignment to 1 protein entry:     NOS2_HUMAN:
    NOS1    NOS3

    NOS2 for paralogs           About GeneDecksing


    5/15 Pseudogenes.org Pseudogenes for NOS2 (see all 15)
    PGOHUM00000247699 PGOHUM00000248028 PGOHUM00000250807 PGOHUM00000237000 PGOHUM00000237005


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: NOS2_HUMAN, P35228
    Polymorphism: Note=Genetic variations in NOS2 are involved in resistance to malaria [MIM:611162]


    10/1440 SNPs in NOS2 are shown (see all 1440)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0363024
    A breast cancer sample4--see VAR_0363022 A S mis40--------
    rs596857461,2
    C--26088338(+) CACGG-/CCCTCC 1 -- int13Minor allele frequency- C:0.00NA CSA 8
    rs58198211,2
    C,F--26106756(+) CAGAAA/-GCTGG 1 -- int17Minor allele frequency- -:0.31NS NA CSA 178
    rs1123369321,2
    C--26115222(+) GCGTGCACA/-  
            
    CACAC
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs594313571,2
    C,F--26115249(+) CACAC-/AC/ACAC/ACACAC
    ACAC
    /ACACACACACAC
    GAATG
    2 -- int1 cds12NA 4
    rs349927771,2
    C--26119841(+) CTACAA/-AAAAA 1 -- int11Minor allele frequency- -:0.00NA 2
    rs289987991,2
    C,F--26126131(-) GGGGGG/-TTCAT 1 -- int16Minor allele frequency- -:0.07NS NA 184
    rs358348121,2
    C--26126817(+) AAAAA-/AGAAAG 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1462260231,2
    --26143243(+) TCCTTA/GGCCTG 1 -- ds50010--------
    rs1154286341,2
    F--26143250(+) CCTGCT/ACCAAA 1 -- ds50011Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for NOS2 (26083792 - 26127555 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NOS2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2715781CNV Deletion23290073
    nsv9533CNV Gain18304495
    esv28579CNV Gain19812545
    dgv943e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): NOS2

    Locus Specific Mutation Databases (LSDB): NOS2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NOS2
    DNA2.0 Custom Variant and Variant Library Synthesis for NOS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 163730   
    OMIM disorders: 145500  611162  
    20/358 diseases for NOS2 (see all 358):    About MalaCards
    virilizing ovarian tumor    pityriasis lichenoides    bladder carcinoma in situ    borderline leprosy
    peyronie's disease    peyronies disease    collagenous colitis    trigonitis
    lymphocytic colitis    internal hemorrhoid    cytokine receptor deficiency    hemorrhoid
    warthin tumor    idiopathic achalasia    myocarditis    colonic disease
    retinal vasculitis    lip cancer    microscopic colitis    choledochal cyst

    3 diseases from the University of Copenhagen DISEASES database for NOS2:
    Vascular disease     Gastrointestinal system disease     Arthritis

    NOS2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/96 Novoseek inferred disease relationships for NOS2 gene (see all 96)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 76.7 531 14657339 (3), 17449036 (3), 16537027 (3), 12613978 (3) (see all 99)
    necrosis 75.9 590 16827641 (4), 17452936 (3), 9856818 (3), 10713108 (3) (see all 99)
    tumors 64.1 1265 11156233 (6), 17980097 (6), 16557582 (5), 20338478 (5) (see all 99)
    shock septic 63.8 96 7536056 (4), 12594864 (3), 14654318 (3), 10791377 (3) (see all 58)
    sepsis 54.4 152 12016107 (5), 17997414 (4), 12594864 (3), 10669117 (3) (see all 72)
    atherosclerosis 51.8 77 8683942 (3), 10073969 (3), 10334927 (2), 11139364 (2) (see all 47)
    neurodegenerative diseases 50.5 18 16144552 (1), 7523410 (1), 11246231 (1), 16807879 (1) (see all 11)
    inflammatory bowel diseases 46.6 44 17955236 (2), 12792224 (2), 10102942 (1), 10630438 (1) (see all 28)
    cell damage 46.4 28 11218753 (2), 9377819 (1), 11139364 (1), 11488434 (1) (see all 22)
    ischemia 46.1 102 15327760 (4), 16154689 (4), 11708836 (3), 8787213 (3) (see all 61)

    Genetic Association Database (GAD): NOS2
    Human Genome Epidemiology (HuGE) Navigator: NOS2 (192 documents)

    Export disorders for NOS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NOS2 gene, integrated from 9 sources (see all 4083) (see top 10):
    (articles sorted by number of sources associating them with NOS2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. (PubMed id 7682706)1, 2, 3, 9 Geller D.A....Billiar T.R. (1993)
    2. A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. (PubMed id 12433515)1, 2, 4, 9 Hobbs M.R....Weinberg J.B. (2002)
    3. Dedifferentiated human ventricular cardiac myocytes express inducible nitric oxide synthase mRNA but not protein in response to IL-1, TNF, IFNgamma, and LPS. (PubMed id 9160867)1, 2, 9 Luss H.... Billiar T.R. (1997)
    4. Influence of nitric oxide synthase gene polymorphisms on the risk of cardiovascular events in rheumatoid arthritis. (PubMed id 19327239)1, 4, 9 Gonzalez-Gay M.A....Martin J. (2009)
    5. Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes. (PubMed id 19859740)1, 4, 9 Levesque M.C....Weinberg J.B. (2010)
    6. Role of inducible nitric oxide synthase in asthma ris k and lung function growth during adolescence. (PubMed id 19996333)1, 4, 9 Islam T....Gilliland F.D. (2010)
    7. The CCTTT pentanucleotide microsatellite in iNOS promoter influences the clinical outcome in P. falciparum infection. (PubMed id 19153766)1, 4, 9 Dhangadamajhi G....Ranjit M.R. (2009)
    8. Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients. (PubMed id 19242068)1, 4, 9 Bohanec Grabar P....Dolzan V. (2009)
    9. NO role of NOS2A susceptibility polymorphisms in rheu matoid arthritis. (PubMed id 19635578)1, 4, 9 VaradAc J....Urcelay E. (2009)
    10. Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase. (PubMed id 10409685)1, 2, 9 Li H.... Poulos T.L. (1999)
    11. Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172. (PubMed id 7531687)1, 2, 9 Hokari A.... Esumi H. (1994)
    12. Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line. (PubMed id 7692964)1, 2, 9 Sherman P.A.... Wood E.R. (1993)
    13. EDNRA variants associate with smooth muscle mRNA leve ls, cell proliferation rates, and cystic fibrosis pulmonary disease severity. (PubMed id 20028935)1, 4 Darrah R....Drumm M.L. (2010)
    14. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    15. Genome-wide association analysis identifies three pso riasis susceptibility loci. (PubMed id 20953189)1, 4 Stuart P.E....Elder J.T. (2010)
    16. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (2009)
    17. Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. (PubMed id 19479237)1, 4 Song X.Y....Chan J.C. (2009)
    18. A candidate gene association study of 77 polymorphism s in migraine. (PubMed id 19559392)1, 4 SchA1rks M....Zee R.Y. (2009)
    19. Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with Type 2 diabetes. (PubMed id 19395279)1, 4 Bagarolli R.A....Saad S.T. (2009)
    20. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. (PubMed id 19263529)1, 4 Zee R.Y....Glynn R.J. (2009)
    21. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (2009)
    22. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
    23. Influence of inducible nitric oxide synthase polymorp hisms in Japanese patients with non-alcoholic fatty liver disease. (PubMed id 19624767)1, 4 Yoneda M....Nakajima A. (2009)
    24. Genetic variation of polymorphic NOS STR locus in ten Indian population groups. (PubMed id 19334623)1, 4 Shazia A....Seshadri M. (2009)
    25. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. (PubMed id 19131662)1, 4 Wang X....Cook N.R. (2009)
    26. Role of inflammation gene polymorphisms on pain sever ity in lung cancer patients. (PubMed id 19773451)1, 4 Reyes-Gibby C.C....Shete S. (2009)
    27. Association of SLC11A1 with tuberculosis and interact ions with NOS2A and TLR2 in African-Americans and Caucasians. (PubMed id 19723394)1, 4 Velez D.R....Scott W.K. (2009)
    28. Inducible nitric oxide synthase promoter polymorphism affords protection against cognitive dysfunction after carotid endarterectomy. (PubMed id 19286578)1, 4 Yocum G.T....Heyer E.J. (2009)
    29. Lead exposure, polymorphisms in genes related to oxid ative stress, and risk of adult brain tumors. (PubMed id 19505917)1, 4 Bhatti P....Rajaraman P. (2009)
    30. Genetic variation in neuronal nitric oxide synthase ( nNOS) gene and susceptibility to cerebral malaria in Indian adults. (PubMed id 19540363)1, 4 Dhangadamajhi G....Ranjit M. (2009)
    31. Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease. (PubMed id 19309520)1, 4 Payton A....Carrol E.D. (2009)
    32. Variation in the Lymphotoxin-alpha/Tumor Necrosis Factor Locus Modifies Risk of Erythema Nodosum in Sarcoidosis. (PubMed id 19225544)1, 4 McDougal K.E....Cutting G.R. (2009)
    33. An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). (PubMed id 19161160)1, 4 Franke B....Blom H.J. (2009)
    34. Functional single nucleotide polymorphism-1026C/A of inducible nitric oxide synthase gene with increased YY1-binding affinity is associated with hypertension in a Chinese Han population. (PubMed id 19402223)1, 4 Fu L....Li Y. (2009)
    35. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (2009)
    36. Suggested association of NOS2A polymorphism in idiopathic achalasia: no evidence in a large case-control study. (PubMed id 19337240)1, 4 Vigo A.G....Ruiz de LeA^n A. (2009)
    37. Genome-wide scan of 500,000 single-nucleotide polymor phisms among responders and nonresponders to interferon beta therapy in multipl e sclerosis. (PubMed id 19667218)1, 4 Comabella M....Montalban X. (2009)
    38. Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma. (PubMed id 19423521)1, 4 Han X....Zhang Y. (2009)
    39. Nitric oxide synthase gene polymorphisms and prostate cancer risk. (PubMed id 19168583)1, 4 Lee K.M....Hayes R.B. (2009)
    40. Investigation of chromosome 17 candidate genes in susceptibility to TB in a South African population. (PubMed id 19147409)1, 4 MAPller M....Hoal E.G. (2009)
    41. Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885)1, 4 Enjuanes A....Campo E. (2008)
    42. Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis. (PubMed id 18974840)1, 4 Atik B....Dean D. (2008)
    43. Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PubMed id 19064572)1, 4 Palmieri R.T.... . (2008)
    44. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (2008)
    45. Candidate genes and cerebral palsy: a population-based study. (PubMed id 18977990)1, 4 Gibson C.S....Nelson K.B. (2008)
    46. TNFA locus is associated with beta degrees 39 thalassemia in Corsica and Sardinia. (PubMed id 19103526)1, 4 Giovannoni L. (2008)
    47. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (2007)
    48. Epithelial inducible nitric-oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output. (PubMed id 12080081)1, 2 Glynne P.A.... Evans T.J. (2002)
    49. Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation. (PubMed id 10074942)1, 2 Fischmann T.O....Weber P.C. (1999)
    50. Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo. (PubMed id 7544004)1, 2 Guo F.H....Erzurum S.C. (1995)
    51. Three members of the nitric oxide synthase II gene family (NOS2A, NOS2B, and NOS2C) colocalize to human chromosome 17. (PubMed id 7558036)1, 2 Bloch K.D.... Bloch D.B. (1995)
    52. Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression. (PubMed id 7522054)1, 2 Maier R.... Lotz M. (1994)
    53. Nitric oxide production by human proximal tubular cells: a novel immunomodulatory mechanism? (PubMed id 7532248)1, 2 McLay J.S....Hawksworth G.M. (1994)
    54. Human retina expresses both constitutive and inducible isoforms of nitric oxide synthase mRNA. (PubMed id 7528017)1, 2 Park C.S.... Krishna G. (1994)
    55. Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte. (PubMed id 7504305)1, 2 Charles I.G.... Moncada S. (1993)
    56. Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors. (PubMed id 15601772)1, 9 Kolodziejski P.J....Eissa N.T. (2004)
    57. Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells. (PubMed id 12533668)1, 9 Ekmekcioglu S....Grimm E.A. (2003)
    58. Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome. (PubMed id 16243805)1, 9 Zhang J....Chen X. (2005)
    59. Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. (PubMed id 15695237)1, 9 Nosho K....Imai K. (2005)
    60. Expression of inducible nitric oxide synthase is significantly correlated with expression of vascular endothelial growth factor and dendritic cell infiltration in patients with advanced gastric carcinoma. (PubMed id 16020977)1, 9 Yamaguchi K....Tsujitani S. (2005)
    61. Estrogen induces nitric oxide production via activation of constitutive nitric oxide synthases in human neuroblastoma cells. (PubMed id 15242984)1, 9 Xia Y. and Krukoff T.L. (2004)
    62. Expression of inducible nitric oxide synthase in human heart failure. (PubMed id 8653828)1, 9 Haywood G.A....Fowler M.B. (1996)
    63. Increased expression of inducible nitric oxide synthase (iNOS) in N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis and prevention of cancer development by ONO-1714, an iNOS inhibitor. (PubMed id 18567618)1, 9 Takahashi M....Wakabayashi K. (2008)
    64. Dynamic receptor-dependent activation of inducible nitric-oxide synthase by ERK-mediated phosphorylation of Ser745. (PubMed id 17804409)1, 9 Zhang Y....Skidgel R.A. (2007)
    65. Binding of CAP70 to inducible nitric oxide synthase and implications for the vectorial release of nitric oxide in polarized cells. (PubMed id 17507652)1, 9 Navarro-Lerida I....Rodriguez-Crespo I. (2007)
    66. Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA. (PubMed id 15609395)1, 9 Wang Y.Z....Cha X.Y. (2005)
    67. Expression of inducible nitric oxide synthase in tumoral and non-tumoral epithelia from bladder cancer patients. (PubMed id 15631946)1, 9 Sandes E.O....Eijan A.M. (2005)
    68. [Expression of inducible nitric oxide synthase mRNA in squamous cell carcinoma of tongue] (PubMed id 12452003)1, 9 Chen W.L....Pan C.B. (2002)
    69. Inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) expression in fulminant hepatic failure. (PubMed id 12399227)1, 9 Leifeld L....Spengler U. (2002)
    70. The physiologic aggresome mediates cellular inactivation of iNOS. (PubMed id 19139419)1, 9 Pandit L....Eissa N.T. (2009)
    71. Prognostic significance of tumor iNOS and COX-2 in stage III malignant cutaneous melanoma. (PubMed id 19039588)1, 9 Johansson C.C....Kiessling R. (2009)
    72. [Increased expression of inducible nitric oxide synthase in chronic hepatitis B patients is correlated with histopathological grading and staging] (PubMed id 18414703)1, 9 Wu J....Fan Y.C. (2008)
    73. Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes. (PubMed id 18313411)1, 9 Kim H.S....Billiar T.R. (2008)
    74. Ligands of peroxisome proliferator-activated receptor inhibit homocysteine-induced DNA methylation of inducible nitric oxide synthase gene. (PubMed id 17492134)1, 9 Jiang Y....Wang S. (2007)
    75. Src-mediated phosphorylation regulates subcellular distribution and activity of human inducible nitric oxide synthase. (PubMed id 16116474)1, 9 Hausel P....Felley-Bosco E. (2006)
    76. Expression of cyclooxygenase-2 and inducible nitric oxide synthase in ovarian surface epithelial carcinomas: is there any correlation with angiogenesis or clinicopathologic parameters? (PubMed id 16681724)1, 9 Ozel E....Karaveli F.S. (2006)
    77. The role of nitric oxide synthases and nitrotyrosine in retinoblastoma. (PubMed id 15754329)1, 9 Adithi M....Krishnakumar S. (2005)
    78. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic adenocarcinoma: correlation with microvessel density. (PubMed id 15222037)1, 9 Kasper H.U....Kern M.A. (2004)
    79. Expression of COX-2, iNOS, p53 and Ki-67 in gastric mucosa-associated lymphoid tissue lymphoma. (PubMed id 15222024)1, 9 Li H.L....Ma F.C. (2004)
    80. Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock. (PubMed id 12578118)1, 9 Collins J.L....Billiar T.R. (2003)
    81. Relationship between the expression of iNOS,VEGF,tumor angiogenesis and gastric cancer. (PubMed id 12174362)1, 9 Song Z.J....Wu Y.E. (2002)
    82. Ubiquitination of inducible nitric oxide synthase is required for its degradation. (PubMed id 12221289)1, 9 Kolodziejski P.J....Eissa N.T. (2002)
    83. Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features. (PubMed id 11978184)1, 9 Feng C.W....Xie X.J. (2002)
    84. Inducible nitric oxide synthase gene promoter polymorphism is associated with increased gastric mRNA expression of inducible nitric oxide synthase and increased risk of gastric carcinoma. (PubMed id 17272999)1, 9 Kaise M....Tajiri H. (2007)
    85. NF-kappaB promotes iNOS and VEGF expression in salivary gland adenoid cystic carcinoma cells and enhances endothelial cell motility in vitro. (PubMed id 19317804)1, 9 Zhang J. and Peng B. (2009)
    86. Not in the mind but in the cell: increased production of cyclo-oxygenase-2 and inducible NO synthase in chronic fatigue syndrome. (PubMed id 17693978)1, 9 Maes M....Bosmans E. (2007)
    87. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. (PubMed id 15683721)1, 9 Jana M....Pahan K. (2005)
    88. Heterogeneous expression of cyclooxygenase-2 and indu cible nitric oxide synthase within colorectal tumors: correlation with tumor an giogenesis. (PubMed id 19497798)1, 9 Cianchi F....Masini E. (2010)
    89. Inhibition of VEGF expression in tongue squamous canc er cells via RNA interference silencing of iNOS gene. (PubMed id 19307105)1, 9 Yan L....Bai Z.B. (2009)
    90. Lack of association of the cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphism with risk of cervical cancer in Korean population. (PubMed id 17404026)1, 9 Lee T.S....Song Y.S. (2007)
    91. Tumor iNOS predicts poor survival for stage III melanoma patients. (PubMed id 16557582)1, 9 Ekmekcioglu S....Grimm E.A. (2006)
    92. Contribution of inducible nitric oxide synthase and cyclooxygenase-2 to apoptosis induction in smooth chorion trophoblast cells of human fetal membrane tissues. (PubMed id 16442500)1, 9 Yuan B....Toyoda H. (2006)
    93. Significance of vascular endothelial growth factor expression and its correlation with inducible nitric oxide synthase in gastric cancer. (PubMed id 15112337)1, 9 Song Z.Y....Qian K.D. (2004)
    94. Activation of cytosolic phospholipase A2alpha through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2. (PubMed id 18029351)1, 9 Xu L....Wu T. (2008)
    95. Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters. (PubMed id 18502573)1, 9 Sawa T....Ohshima H. (2008)
    96. Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels. (PubMed id 17189532)1, 9 Batra J....Ghosh B. (2007)
    97. Association between achalasia and nitric oxide synthase gene polymorphisms. (PubMed id 16848803)1, 9 Mearin F....Lanas A. (2006)
    98. Inducible and endothelial nitric oxide synthase genes polymorphism in inflammatory bowel disease. (PubMed id 16634870)1, 9 Oliver J....Martin J. (2006)
    99. [Expression of hypoxia-inducible factor-1alpha in nasal polyps and it's correlation with vascular endothelial growth factor and inducible nitric oxide synthase] (PubMed id 16229182)1, 9 Liu Y....Zhang P. (2005)
    100. Impaired nitric oxide synthase-2 signaling pathway in cystic fibrosis airway epithelium. (PubMed id 15107292)1, 9 Zheng S....Erzurum S.C. (2004)
    101. Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II. (PubMed id 11880293)1, 9 Pechkovsky D.V....Muller-Quernheim J. (2002)
    102. Expression of endothelial and inducible nitric oxide synthase in non-pregnant and decidualized human endometrium. (PubMed id 9239710)1, 9 Telfer J.F....Cameron I.T. (1997)
    103. Src kinase-mediated phosphorylation stabilizes induci ble nitric-oxide synthase in normal cells and cancer cells. (PubMed id 19875457)1, 9 Tyryshkin A....Eissa N.T. (2010)
    104. Histo- and immunocytochemical detection of inducible NOS and TNF-alpha in the locus coeruleus of human opiate addicts. (PubMed id 19038328)1, 9 Dyuizen I. and Lamash N.E. (2009)
    105. Nasal mucosal expression of nitric oxide synthases in patients with allergic rhinitis and its relation to asthma. (PubMed id 18254476)1, 9 Yuksel H....Ozbilgin K. (2008)
    106. Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2. (PubMed id 18753331)1, 9 Tsutsumi S....Mendelsohn M.E. (2008)
    107. Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis. (PubMed id 18472017)1, 9 Grimm E.A....Ekmekcioglu S. (2008)
    108. Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study. (PubMed id 17328085)1, 9 Li C....Wei Q. (2007)
    109. [Expression of cell adhesion molecule and nitric oxide synthase in nasal mucosa in allergic rhinitis] (PubMed id 16780147)1, 9 Li Y....Zhang Q. (2006)
    110. Mifepristone-induced nitric oxide release and expression of nitric oxide synthases in the human cervix during early pregnancy. (PubMed id 16684839)1, 9 Vaisanen-Tommiska M....Mikkola T.S. (2006)
    111. UVB radiation-mediated expression of inducible nitric oxide synthase activity and the augmenting role of co-induced TNF-alpha in human skin endothelial cells. (PubMed id 15482484)1, 9 Suschek C.V....Kolb-Bachofen V. (2004)
    112. Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria. (PubMed id 12552317)1, 9 Burgner D....Kwiatkowski D.P. (2003)
    113. Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study. (PubMed id 12490535)1, 9 Levecque C....Chartier-Harlin M.C. (2003)
    114. Inducible nitric oxide, synthase in renal cell carcinoma: expression in tumor thrombi and induction under hypoxic conditions. (PubMed id 14981908)1, 9 Hara N....Tomita Y. (2003)
    115. Nitric oxide synthase expression in human bladder cancer and its relation to angiogenesis. (PubMed id 12937869)1, 9 Lin Z....Zhu S. (2003)
    116. Study on the Relationship between susceptibility of stomach neoplasm cancer and polymorphism of inducible nitric oxide synthase gene. (PubMed id 12482371)1, 9 Shen J....Xu X. (2002)
    117. (CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy. (PubMed id 11692109)1, 9 Konno S....Nishimura M. (2001)
    118. Protective effect of sulforaphane on human vascular e ndothelial cells against lipopolysaccharide-induced inflammatory damage. (PubMed id 20405237)1, 9 Shan Y....Wang S. (2010)
    119. Ultrastructural immunogold localization of nitric oxi de synthase isoforms in rat and human eosinophils. (PubMed id 20232214)1, 9 Saluja R....Dikshit M. (2010)
    120. Nitric oxide synthase in gingival tissues of patients with chronic periodontitis and with and without diabetes. (PubMed id 20059423)1, 9 Pan Z....Bulut S. (2010)
    121. Expression and prognostic significance of iNOS in uve al melanoma. (PubMed id 19847812)1, 9 Johansson C.C....Kiessling R. (2010)
    122. Delayed and acute effects of interferon-gamma on activity of an inwardly rectifying K+ channel in cultured human proximal tubule cells. (PubMed id 18945831)1, 9 Nakamura K....Kubokawa M. (2009)
    123. Widespread expression of inducible NOS and citrulline in lupus nephritis tissues. (PubMed id 19184355)1, 9 Bollain-y-Goytia J.J....Herrera-Esparza R. (2009)
    124. Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin. (PubMed id 19130609)1, 9 Fetz V....Knauer S.K. (2009)
    125. Cross-talk between inducible nitric oxide synthase an d cyclooxygenase in Helicobacter-pylori-induced gastritis. (PubMed id 19797925)1, 9 Franco L. and Talamini G. (2009)
    126. Role of p38 MAPK pathway in induction of iNOS express ion in neutrophils and peripheral blood mononuclear cells in patients with squa mous cell carcinoma of the oral cavity. (PubMed id 19837302)1, 9 Ratajczak-Wrona W....Piotrowski L. (2009)
    127. Ezrin and inducible nitric oxide synthase in malignan t proliferation of salivary gland pleomorphic adenoma. (PubMed id 19799816)1, 9 Wang Y.Y....Li J.S. (2009)
    128. (CCTTT)n polymorphism of NOS2A in nasal polyposis and asthma: a case-control study. (PubMed id 18714530)1, 9 Pascual M....Lorente F. (2008)
    129. Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. (PubMed id 17849424)1, 9 Vaninetti N.M....Casson A.G. (2008)
    130. Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma. (PubMed id 17657783)1, 9 Brennan P.A....Thomas G.J. (2008)
    131. Role of nitric oxide synthase/arginase balance in bronchial reactivity in patients with chronic obstructive pulmonary disease. (PubMed id 17675371)1, 9 Tadie J.M....Delclaux C. (2008)
    132. Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species. (PubMed id 18091741)1, 9 Zhen J....Zhou X.J. (2008)
    133. Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils. (PubMed id 18515325)1, 9 Alba G....Sobrino F. (2008)
    134. Nitric oxide overproduction derived from inducible nitric oxide synthase increases cardiomyocyte apoptosis in human atrial fibrillation. (PubMed id 18585800)1, 9 Han W....Huo H. (2008)
    135. Polymorphisms in angiogenesis-related genes and prostate cancer. (PubMed id 18398039)1, 9 Jacobs E.J....Rodriguez C. (2008)
    136. Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion. (PubMed id 18024942)1, 9 Tsui J.C....Dashwood M.R. (2007)
    137. Inducible nitric oxide synthase promoter polymorphism, cigarette smoking, and urothelial carcinoma risk. (PubMed id 17482959)1, 9 Shen C.H....Chiou H.Y. (2007)
    138. Influence of the inducible nitric oxide synthase gene (NOS2A) on inflammatory bowel disease susceptibility. (PubMed id 17955236)1, 9 Martin M.C....Urcelay E. (2007)
    139. Dissociation between adipose nitric oxide synthase expression and tissue metabolism. (PubMed id 17456572)1, 9 Engeli S....Jordan J. (2007)
    140. Inducible nitric oxide synthase (iNOS) gene polymorphism in pre-eclampsia: a pilot study in North India. (PubMed id 17991113)1, 9 Bhatnagar S....Sarma P.U. (2007)
    141. Lack of association between NOS2 pentanucleotide repeat polymorphism and asthma phenotypes or exhaled nitric oxide concentration. (PubMed id 16703578)1, 9 Leung T.F....Wong G.W. (2006)
    142. Analysis of the inducible nitric oxide synthase gene polymorphisms in Czech patients with atopic diseases. (PubMed id 17177683)1, 9 Holla L.I....Vasku A. (2006)
    143. Nitric oxide synthase gene polymorphisms and nephropathy in Asians with Type 2 diabetes. (PubMed id 17070441)1, 9 Liao L....Lee K.O. (2006)
    144. [Polymorphic markers of the NO synthase genes and genetic predisposition to diabetic polyneuropathy in patients with type 1 diabetes mellitus] (PubMed id 15856945)1, 9 Zotova E.V....Nosikov V.V. (2005)
    145. Increased risk of intestinal type of gastric adenocarcinoma in Japanese women associated with long forms of CCTTT pentanucleotide repeat in the inducible nitric oxide synthase promoter. (PubMed id 15617837)1, 9 Tatemichi M....Ohshima H. (2005)
    146. Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence. (PubMed id 12800233)1, 9 Xu M.H....Lin J. (2003)
    147. A functional variant of the iNOS gene flanking region is associated with LAD coronary artery disease: an autopsy study. (PubMed id 14636285)1, 9 Kunnas T.A....Karhunen P.J. (2003)
    148. Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis. (PubMed id 12598314)1, 9 Cianchi F....Masini E. (2003)
    149. Immunocytochemical localization of cytokines and inducible nitric oxide synthase (iNOS) in oral mucosa and lymph nodes of patients with paracoccidioidomycosis. (PubMed id 12824008)1, 9 Neworal E.P....Blotta M.H. (2003)
    150. Immunohistochemical analysis of inducible nitric oxide synthase (iNOS) and heat shock proteins (HSPs) in ameloblastomas. (PubMed id 12406306)1, 9 Kumamoto H....Ooya K. (2002)
    151. Genetic determinants of rheumatoid arthritis: the inducible nitric oxide synthase (NOS2) gene promoter polymorphism. (PubMed id 12140750)1, 9 Pascual M....Martin J. (2002)
    152. Expression of nitric oxide synthase in human central nervous system tumors. (PubMed id 7531613)1, 9 Cobbs C.S....Israel M.A. (1995)
    153. The nongenomic effects of progesterone in repressing iNOS activation through P38MAPK pathways in gonococci-infected polymorphonuclea r leukocytes and the clinical significance. (PubMed id 20155468)1, 9 Chen R....Chen H. (2010)
    154. Transient hyperoxic reoxygenation reduces cytochrome C oxidase activity by increasing superoxide dismutase and nitric oxide. (PubMed id 20086011)1, 9 Arab A....Hehrlein C. (2010)
    155. [Polymorphism of eNOS and iNOS Genes and Chronic Hear t Failure in Patients With Ischemic Heart Disease.] (PubMed id 20459417)1, 9 Tepliakov A.T....Karpov R.S. (2010)
    156. Nitric oxide synthase isoenzyme expression and activi ty in peripheral lung tissue of patients with chronic obstructive pulmonary dis ease. (PubMed id 19797159)1, 9 Brindicci C....Ito K. (2010)
    157. Nitric oxide increases Wnt-induced secreted protein-1 (WISP-1/CCN4) expression and function in colitis. (PubMed id 19238344)1, 9 Wang H....MacNaughton W.K. (2009)
    158. Exposure of human keratinocytes to ischemia, hypergly cemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase. (PubMed id 19539448)1, 9 Portugal-Cohen M. and Kohen R. (2009)
    159. Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase. (PubMed id 19737939)1, 9 Xia C....Kim J.J. (2009)
    160. Nitric oxide synthases in infants and children with p ulmonary hypertension and congenital heart disease. (PubMed id 19912632)1, 9 Hoehn T....Wadsworth R.M. (2009)
    161. YC-1 stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells. (PubMed id 18923065)1, 9 Liu X.M....Durante W. (2009)
    162. CHIP facilitates ubiquitination of inducible nitric o xide synthase and promotes its proteasomal degradation. (PubMed id 19362296)1, 9 Chen L....Yin Z. (2009)
    163. Identification of a flavin mononucleotide module resi due critical for activity of inducible nitrite oxide synthase. (PubMed id 19828635)1, 9 Liu X.D....Eissa N.T. (2009)
    164. Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection. (PubMed id 19291698)1, 9 Li W....Zhu Y. (2009)
    165. Expression of IGF-1R and iNOS in nasal polyps; epithelial cell homeostasis and innate immune mechanisms in pathogenesis of nasal polyposis. (PubMed id 19381485)1, 9 FundovA! P....TlaskalovA!-HogenovA! H. (2008)
    166. Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease. (PubMed id 18579559)1, 9 Calvisi D.F....Pascale R.M. (2008)
    167. Heme oxygenase-1 is a critical regulator of nitric oxide production in enterohemorrhagic Escherichia coli-infected human enterocytes. (PubMed id 18390757)1, 9 Vareille M....Gobert A.P. (2008)
    168. Inducible nitric oxide synthase activity is increased in patients with rheumatoid arthritis and contributes to endothelial dysfuncti on. (PubMed id 18571252)1, 9 MAoki-PetAojAo K.M....Wilkinson I.B. (2008)
    169. Production of nitric oxide and expression of inducible nitric oxide synthase in ovarian cystic tumors. (PubMed id 19132106)1, 9 Nomelini R.S....Murta E.F. (2008)
    170. Cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphisms and risk of reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma. (PubMed id 18349295)1, 9 Ferguson H.R....Hardie L.J. (2008)
    171. Stimulation of iNOS expression and apoptosis resistance in B-cell chronic lymphocytic leukemia (B-CLL) cells through engagement of Toll-like receptor 7 (TLR-7) and NF-kappaB activation. (PubMed id 18474259)1, 9 Hammadi A....Kolb J.P. (2008)
    172. Influence of glucosamine sulphate on oxidative stress in human osteoarthritic chondrocytes: effects on HO-1, p22(Phox) and iNOS expression. (PubMed id 18077487)1, 9 Valvason C....Punzi L. (2008)
    173. Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. (PubMed id 18580885)1, 9 Barcellos L.F....Oksenberg J.R. (2008)
    174. Preliminary evidences of a NOS2A protective effect from relapsing-remitting multiple sclerosis. (PubMed id 17854833)1, 9 Manna I....Quattrone A. (2008)
    175. Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma. (PubMed id 17149600)1, 9 Lan Q....Chanock S. (2007)
    176. Polymorphisms in genes involved in innate immunity predispose toward mycetoma susceptibility. (PubMed id 17709521)1, 9 van de Sande W.W....van Belkum A. (2007)
    177. Arginine and immunity. (PubMed id 17513447)7, 9 Popovic P.J....Ochoa J.B. (2007)
    178. Early upregulation of iNOS mRNA expression and increase in NO metabolites in pressurized renal epithelial cells. (PubMed id 17881462)1, 9 Broadbelt N.V....Felsen D. (2007)
    179. IL-4 stimulates the expression of CXCL-8, E-selectin, VEGF, and inducible nitric oxide synthase mRNA by equine pulmonary artery endothelial cells. (PubMed id 17494951)7, 9 Huang H....Lavoie J.P. (2007)
    180. Polymorphisms within inflammatory genes and colorectal cancer. (PubMed id 17062130)1, 9 Landi S....Moreno V. (2006)
    181. Investigations on the inducible and endothelial nitric oxide synthases in human breast cancer cell line MCF-7 - estrogen has an influence on e-NOS, but not on i-NOS. (PubMed id 16326029)1, 9 Loibl S....Kaufmann M. (2006)
    182. Pulmonary hypertension in human newborns with congenital diaphragmatic hernia is associated with decreased vascular expression of nitric-oxide synthase. (PubMed id 16456243)1, 9 Shehata S.M....Tibboel D. (2006)
    183. Inducible nitric oxide synthase, nitrotyrosine and apoptosis in gastric adenocarcinomas and their correlation with a poor survival. (PubMed id 15849807)1, 9 Li L.G. and Xu H.M. (2005)
    184. An investigation of NOS2A promoter polymorphisms in Australian multiple sclerosis patients. (PubMed id 15856071)1, 9 Bugeja M.J....Stewart G.J. (2005)
    185. Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase. (PubMed id 16260491)1, 9 Nathan C....Beal M.F. (2005)
    186. Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages. (PubMed id 16335796)1, 9 Woo C.W....O K. (2005)
    187. Relationship between inducible nitric oxide synthase expression and angiogenesis in primary gallbladder carcinoma tissue. (PubMed id 14991947)1, 9 Niu X.J....Qing X.L. (2004)
    188. Inducible but not endothelial nitric oxide synthase polymorphism is associated with susceptibility to rheumatoid arthritis in northwest Spain. (PubMed id 15226517)1, 9 Gonzalez-Gay M.A....Martin J. (2004)
    189. Investigation of an inducible nitric oxide synthase gene (NOS2A) polymorphism in a multiple sclerosis population. (PubMed id 15275951)1, 9 Tajouri L....Griffiths L.R. (2004)
    190. Nitric oxide synthase in healthy and inflamed human dental pulp. (PubMed id 15044505)1, 9 Di Nardo Di Maio F....Felaco M. (2004)
    191. Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. (PubMed id 15174013)1, 9 Barcellos L.F....Oksenberg J.R. (2004)
    192. Post-transcriptional regulation of inducible nitric oxide synthase in chronic lymphocytic leukemia B cells in pro- and antiapoptotic culture conditions. (PubMed id 14574328)1, 9 Tiscornia A.C....Pritsch O. (2004)
    193. Increased oxidative DNA damage, inducible nitric oxide synthase, nuclear factor kappaB expression and enhanced antiapoptosis-related proteins in Helicobacter pylori-infected non-cardiac gastric adenocarcinoma. (PubMed id 15259072)1, 9 Chang C.S....Wang C.J. (2004)
    194. JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes. (PubMed id 15115662)1, 9 Zhang B....Harbrecht B.G. (2004)
    195. A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer. (PubMed id 15484300)1, 9 Shen J....Wang X.R. (2004)
    196. Coupled induction of iNOS and p53 upregulation in renal resident cells may be linked with apoptotic activity in the pathogenesis of progressive IgA nephropathy. (PubMed id 15284293)1, 9 Qiu L.Q....Hsu S.I. (2004)
    197. Nitric oxide synthase gene polymorphisms and diabetic nephropathy. (PubMed id 12687343)1, 9 Rippin J.D....Bain S.C. (2003)
    198. Down-regulation of nitric oxide synthase-2 and cyclooxygenase-2 pathways by p53 in squamous cell carcinoma. (PubMed id 12875991)1, 9 Gallo O....Capaccioli S. (2003)
    199. Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains. (PubMed id 12777376)1, 9 Guan Z.W....Iyanagi T. (2003)
    200. Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6. (PubMed id 12590140)1, 9 Warke V.G....Tsokos G.C. (2003)
    201. Lymphocytic infiltration and expression of inducible nitric oxide synthase in human duodenal and colonic mucosa is a characteristic feature of ankylosing spondylitis. (PubMed id 14677189)1, 9 Lamarque D....Claudepierre P. (2003)
    202. No association of inducible nitric oxide synthase gene ( NOS2A) to multiple sclerosis. (PubMed id 12736741)1, 9 Blanco Y....Saiz A. (2003)
    203. Immunohistochemical expression of cytokine induced nitric oxide synthase in colorectal carcinoma. (PubMed id 11956620)1, 9 Nozoe T....Korenaga D. (2002)
    204. Human renal epithelial cells express iNOS in response to cytokines but not bacteria. (PubMed id 11849384)1, 9 Poljakovic M....Persson K. (2002)
    205. Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis. (PubMed id 12445411)1, 9 Sanz-Cameno P....Moreno-Otero R. (2002)
    206. Significant association of longer forms of CCTTT Microsatellite repeat in the inducible nitric oxide synthase promoter with severe malaria in Thailand. (PubMed id 12195390)1, 9 Ohashi J....Tokunaga K. (2002)
    207. Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma. (PubMed id 12374680)1, 9 Ikeguchi M....Kaibara N. (2002)
    208. Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity. (PubMed id 12097137)1, 9 Lanone S....Mebazaa A. (2002)
    209. Hepatocyte growth factor induced human trophoblast motility involves phosphatidylinositol-3-kinase, mitogen-activated protein kinase, and inducible nitric oxide synthase. (PubMed id 12243747)1, 9 Cartwright J.E....Whitley G.S. (2002)
    210. Inducible nitric oxide synthase is expressed in synovial fluid granulocytes. (PubMed id 12296866)1, 9 Cedergren J....Skogh T. (2002)
    211. Nitric oxide synthase gene polymorphisms in Alzheimer's disease and dementia with Lewy bodies. (PubMed id 11297817)1, 9 Singleton A.B....Morris C.M. (2001)
    212. Antifungal imidazoles block assembly of inducible NO synthase into an active dimer. (PubMed id 9873034)7, 9 Sennequier N....Stuehr D.J. (1999)
    213. Nitric oxide inhibits HIV tat-induced NF-kappaB activation. (PubMed id 10393859)1, 9 Chen F....Demers L.M. (1999)
    214. Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome. (PubMed id 10068656)1, 9 Hori K....Clouse K.A. (1999)
    215. Inducible nitric oxide synthase in the liver: regulation and function. (PubMed id 9721329)2, 9 Taylor B.S.... Billiar T.R. (1998)
    216. Mechanism of nitric oxide-dependent killing of Mycobacterium bovis BCG in human alveolar macrophages. (PubMed id 9284131)1, 9 Nozaki Y....Shimokata K. (1997)
    217. Constitutive expression and structural diversity of inducible isoform of nitric oxide synthase in human tissues. (PubMed id 8699932)1, 9 Park C.S....Krishna G. (1996)
    218. Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain. (PubMed id 7561697)1, 9 Koka P....Merrill J.E. (1995)
    219. Inducible nitric oxide synthase in a human glioblastoma cell line. (PubMed id 7528267)2, 9 Fujisawa H.... Esumi H. (1995)
    220. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. (PubMed id 7524082)1, 9 Asano K....Stamler J.S. (1994)
    221. Positive feedback regulation of human inducible nitric -oxide synthase expression by Ras protein S-nitrosylation. (PubMed id 23599434)1 Lee M. and Choy J.C. (2013)
    222. Cell stress molecules in the skeletal muscle of GNE my opathy. (PubMed id 23496965)1 Fischer C....Schmidt J. (2013)
    223. Intestinal anti-inflammatory activity of red wine extr act: unveiling the mechanisms in colonic epithelial cells. (PubMed id 23233037)1 Nunes C....Laranjinha J. (2013)
    224. Role of AP-1 family proteins in regulation of inducibl e nitric oxide synthase (iNOS) in human neutrophils. (PubMed id 22734893)1 Ratajczak-Wrona W....Iwaniuk A. (2013)
    225. Cytoprotective signaling associated with nitric oxide upregulation in tumor cells subjected to photodynamic therapy-like oxidative str ess. (PubMed id 23261943)1 Bhowmick R. and Girotti A.W. (2013)
    226. Expressions of candidate molecules in the human fallop ian tube and chorionic villi of tubal pregnancy exposed to levonorgestrel emerge ncy contraception. (PubMed id 23687977)1 Huang C....Zhang J. (2013)
    227. Loss of methylation in CpG sites in the NF-kB enhancer elements of inducible nitric oxide synthase is responsible for gene induction i n human articular chondrocytes. (PubMed id 23239081)1 de Andres M.C....Oreffo R.O. (2013)
    228. A non-synonymous SNP in the NOS2 associated with septi c shock in patients with sepsis in Chinese populations. (PubMed id 23192595)1 Wang Z....Zhou G. (2013)
    229. TNF-a and IFN-g are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis. (PubMed id 22992806)1 Viard-Leveugle I....French L.E. (2013)
    230. Proteomic analysis of the NOS2 interactome in human ai rway epithelial cells. (PubMed id 23438482)1 Foster M.W....Marshall H.E. (2013)
    231. NPM-ALK up-regulates iNOS expression through a STAT3/m icroRNA-26a-dependent mechanism. (PubMed id 23338972)1 Zhu H....Amin H.M. (2013)
    232. Induction and stability of human Th17 cells require en dogenous NOS2 and cGMP-dependent NO signaling. (PubMed id 23797095)1 Obermajer N....Kalinski P. (2013)
    233. Inducible nitric oxide synthase haplotype associated w ith hypertension and responsiveness to antihypertensive drug therapy. (PubMed id 23266817)1 Oliveira-Paula G.H....Tanus-Santos J.E. (2013)
    234. Human inducible nitric oxide synthase (iNOS) expressio n depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation factor 4E (elF4E)-mediated nucleocytoplasmic mRNA transport. (PubMed id 23471078)1 Bollmann F....Pautz A. (2013)
    235. miRNA-939 regulates human inducible nitric oxide synth ase posttranscriptional gene expression in human hepatocytes. (PubMed id 22451906)1 Guo Z....Geller D.A. (2012)
    236. [The expression and correlation of inducible nitric ox ide synthase, Bax and Bcl-2 in nasal polyps]. (PubMed id 22675938)1 Liu Y....Wu W. (2012)
    237. Single nucleotide polymorphisms in the NOS2 and NOS3 g enes are associated with exhaled nitric oxide. (PubMed id 22368302)1 Dahgam S....Olin A.C. (2012)
    238. Why does the fallopian tube fail in ectopic pregnancy? The role of activins, inducible nitric oxide synthase, and MUC1 in ectopic impl antation. (PubMed id 22425195)1 Refaat B....Ledger W. (2012)
    239. Ultrasonographic measures of synovitis in an early pha se clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibi tor) in rheumatoid arthritis. (PubMed id 22409880)1 Seymour M....Taylor P.C. (2012)
    240. Interaction among nitric oxide (NO)-related genes in m igraine susceptibility. (PubMed id 22865486)1 Goncalves F.M....Tanus-Santos J.E. (2012)
    241. Maternal iNOS genetic polymorphisms and hypertensive d isorders of pregnancy. (PubMed id 21716319)1 Amaral L.M....Tanus-Santos J.E. (2012)
    242. Structure and dynamics of calmodulin (CaM) bound to ni tric oxide synthase peptides: effects of a phosphomimetic CaM mutation. (PubMed id 22486744)1 Piazza M....Guillemette J.G. (2012)
    243. Single nucleotide polymorphisms in NOS2A and NOS3 gene s are not associated with treatment response of non-small cell lung cancer patie nts following the definitive radiochemotherapy. (PubMed id 22862164)1 Zhang J....Huang W. (2012)
    244. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    245. Association of NOS2 and potential effect of VEGF, IL6, CCL2 and IL1RN polymorphisms and haplotypes on susceptibility to GCA--a simulta neous study of 130 potentially functional SNPs in 14 candidate genes. (PubMed id 22258388)1 Enjuanes A....Cid M.C. (2012)
    246. Transactivation of inducible nitric oxide synthase gen e by Kruppel-like factor 6 regulates apoptosis during influenza A virus infectio n. (PubMed id 22711891)1 Mgbemena V....Bose S. (2012)
    247. Helicobacter pylori regulates iNOS promoter by histone modifications in human gastric epithelial cells. (PubMed id 22215089)1 Angrisano T....Pero R. (2012)
    248. Hypoxia induces nitric oxide synthase in rheumatoid sy noviocytes: consequences on NADPH oxidase regulation. (PubMed id 22329647)1 Chenevier-Gobeaux C....Borderie D. (2012)
    249. Formation of ternary complex of human biliverdin reduc tase-protein kinase Cd-ERK2 protein is essential for ERK2-mediated activation of Elk1 protein, nuclear factor-kB, and inducible nitric-oxidase synthase (iNOS). (PubMed id 22065579)1 Gibbs P.E....Maines M.D. (2012)
    250. Obesity, insulin resistance, and skeletal muscle nitri c oxide synthase. (PubMed id 22797309)1 Kraus R.M....Hickner R.C. (2012)
    251. Expression of nitric oxide synthases in leukocytes in nasal polyps. (PubMed id 22374200)1 Yoshimura T....Befus A.D. (2012)
    252. The expression of genes encoding for COX-2, MPO, iNOS, and sPLA2-IIA in patients with recurrent depressive disorder. (PubMed id 22331023)1 Gal/ecki P....Szemraj J. (2012)
    253. Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children. (PubMed id 22055874)1 Salam M.T....Gilliland F.D. (2012)
    254. Acute pancreatitis is associated with Ser608Leu iNOS p olymorphism. (PubMed id 23438852)1 Ozhan G....Alpertunga B. (2012)
    255. Effects of Feiyanning Decoction, a compound traditiona l Chinese medicine, on iNOS and COX-2 expressions induced by tumor necrosis fact or-a in lung adenocarcinoma cell line. (PubMed id 22704420)1 Wang J.Y....Wang Q. (2012)
    256. Production of nitric oxide is lower in Shiga toxin-sti mulated neutrophils of infants compared to those of children or adults. (PubMed id 23089636)1 Tsuji S....Kaneko K. (2012)
    257. Inducible nitric oxide synthase haplotype associated w ith migraine and aura. (PubMed id 22234503)1 de O S Mansur T....Tanus-Santos J.E. (2012)
    258. Nitric oxide synthase and tyrosine nitration in idiopa thic asthenozoospermia: an immunohistochemical study. (PubMed id 22244784)1 Salvolini E....Balercia G. (2012)
    259. Nos2 inactivation promotes the development of medullob lastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precu rsor migration. (PubMed id 22438824)1 Haag D....Lichter P. (2012)
    260. High glucose decreases expression and activity of p-gl ycoprotein in cultured human retinal pigment epithelium possibly through iNOS in duction. (PubMed id 22363694)1 Zhang Y....Ruan X. (2012)
    261. The apoptosis pathway and the genetic predisposition t o Achilles tendinopathy. (PubMed id 22588838)1 Nell E.M....September A.V. (2012)
    262. Inducible nitric oxide synthetase genotype and Helicob acter pylori infection affect gastric cancer risk. (PubMed id 23002365)1 Rafiei A....Merrell D.S. (2012)
    263. Oct-1 cooperates with the TATA binding initiation comp lex to control rapid transcription of human iNOS. (PubMed id 22349263)1 Reveneau S....Pance A. (2012)
    264. Inhibition of cyclooxygenase-2 and inducible nitric ox ide synthase by silymarin in proliferating mesenchymal stem cells: comparison wi th glutathione modifiers. (PubMed id 21710354)1 Ahmadi-Ashtiani H....Barkhordari E. (2012)
    265. Expression levels of cyclooxygenase-2, tumor necrosis factor-a and inducible NO synthase in placental tissue of normal and preeclampti c pregnancies. (PubMed id 22014124)1 Goksu Erol A.Y....Yildiz S.E. (2012)
    266. Comparing the temperature dependence of FMN to heme el ectron transfer in full length and truncated inducible nitric oxide synthase pro teins. (PubMed id 22198200)1 Li W....Feng C. (2012)
    267. [Construction of A eukaryotic expression vector carryi ng the iNOS gene and its effect on A549 lung cancer cells]. (PubMed id 22613330)1 Ye S....Zhu W. (2012)
    268. Anti-inflammatory potential of an ethyl acetate fracti on isolated from Justicia gendarussa roots through inhibition of iNOS and COX-2 expression via NF-kB pathway. (PubMed id 22063737)1 Kumar K.S....Helen A. (2012)
    269. Nitric oxide synthase and breast cancer: role of TIMP- 1 in NO-mediated Akt activation. (PubMed id 22957045)1 Ridnour L.A....Wink D.A. (2012)
    270. The role of inducible nitric oxide synthase and haem o xygenase 1 in growth and development of dental tissue'. (PubMed id 22147556)1 Speranza L....Grilli A. (2012)
    271. Nitric oxide mediates low magnesium inhibition of oste oblast-like cell proliferation. (PubMed id 22209000)1 Leidi M....Maier J.A. (2012)
    272. Arginine-nitric oxide-polyamine metabolism in periodo ntal disease. (PubMed id 20831369)1 Ozer L....Ozmeric N. (2011)
    273. The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC. (PubMed id 21799753)1 Ohri C.M....Bradding P. (2011)
    274. Functional variants in NOS1 and NOS2A are not associa ted with progressive hearing loss in MAcniA"re's disease in a European Caucasian population. (PubMed id 21612410)1 Gazquez I....Lopez-Nevot M.A. (2011)
    275. Association of the pentanucleotide repeat polymorphis m in NOS2 promoter region with susceptibility to migraine in a Chinese populati on. (PubMed id 20874490)1 Jia S....Gao Y. (2011)
    276. [Effects of hypoxia inducible factor-1 a siRNA on indu cible nitric oxide synthase expression in HaCaT cells]. (PubMed id 22086003)1 Li Y....Wen H. (2011)
    277. NF-kappaB-mediated modulation of inducible nitric oxi de synthase activity controls induction of the Epstein-Barr virus productive cy cle by transforming growth factor beta 1. (PubMed id 21507981)1 Oussaief L....Joab I. (2011)
    278. Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human periphera l blood mononuclear cells. (PubMed id 21722677)1 Saluja R....Dikshit M. (2011)
    279. Expression of nitric oxide synthases in primary cilia ry dyskinesia. (PubMed id 21663943)1 Degano B....Arnal J.F. (2011)
    280. Hepatitis B virus X protein regulates hepatic glucose homeostasis via activation of inducible nitric oxide synthase. (PubMed id 21690090)1 Shin H.J....Yu D.Y. (2011)
    281. Inducible nitric oxide synthase expression correlates with angiogenesis, lymphangiogenesis, and poor prognosis in gastric cancer pat ients. (PubMed id 21333324)1 Zhang W....Tao H.Q. (2011)
    282. The ECS(SPSB) E3 ubiquitin ligase is the master regul ator of the lifetime of inducible nitric-oxide synthase. (PubMed id 21549100)1 Matsumoto K....Miwa S. (2011)
    283. Effect of solution viscosity on intraprotein electron transfer between the FMN and heme domains in inducible nitric oxide synthase. (PubMed id 21803041)1 Li W....Feng C. (2011)
    284. [Expression of iNOS protein and gliacyte apoptosis in neonatal rats with white matter damage]. (PubMed id 21507301)1 Wang H.Q....Guo W.J. (2011)
    285. Analysis of inducible nitric oxide synthase gene polym orphisms in vitiligo in Han Chinese people. (PubMed id 22205923)1 Zhang Y....Gao T. (2011)
    286. Growth hormone releasing hormone induces the expressi on of nitric oxide synthase. (PubMed id 20518847)1 Barabutis N....Schally A.V. (2011)
    287. Role of snail activation in alcohol-induced iNOS-media ted disruption of intestinal epithelial cell permeability. (PubMed id 21535025)1 Forsyth C.B....Keshavarzian A. (2011)
    288. A novel pathway for receptor-mediated post-translation al activation of inducible nitric oxide synthase. (PubMed id 20015194)1 Brovkovych V....Skidgel R.A. (2011)
    289. Dual specificity phosphatase 1 regulates human induci ble nitric oxide synthase expression by p38 MAP kinase. (PubMed id 21547253)1 Turpeinen T....Korhonen R. (2011)
    290. Food contaminant acrylamide increases expression of C ox-2 and nitric oxide synthase in breast epithelial cells. (PubMed id 20713430)1 Lyn-Cook L.E....Hammons G.J. (2011)
    291. I9Np63I+/IRF6 interplay activates NOS2 transcription an d induces autophagy upon tobacco exposure. (PubMed id 21129360)1 Ratovitski E.A. (2011)
    292. PDE-5 and NOS II mRNA expression in menopausal women: a molecular biology study. (PubMed id 20177899)1 Pace G....Vicentini C. (2011)
    293. Ser608Leu polymorphisms in the nitric oxide synthase- 2 gene may influence urinary bladder cancer pathogenesis. (PubMed id 21612325)1 Ryk C....De Verdier P.J. (2011)
    294. A follow-up case-control association study of tractab le (druggable) genes in recurrent major depression. (PubMed id 21630437)1 Schosser A....McGuffin P. (2011)
    295. iNOS induction and PARP-1 activation in human atheros clerotic lesions: an immunohistochemical and ultrastructural approach. (PubMed id 20619687)1 Perrotta I....Cassese M. (2011)
    296. S-nitrosation of arginase 1 requires direct interacti on with inducible nitric oxide synthase. (PubMed id 21533769)1 Dunn J....Santhanam L. (2011)
    297. Expression of TLR 2, TLR 4 and iNOS in cervical monocy tes of Chlamydia trachomatis-infected women and their role in host immune respon se. (PubMed id 21883620)1 Agrawal T....Mittal A. (2011)
    298. Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins. (PubMed id 21199876)1 Nishiya T....Miwa S. (2011)
    299. Glioma stem cell proliferation and tumor growth are p romoted by nitric oxide synthase-2. (PubMed id 21729780)1 Eyler C.E....Rich J.N. (2011)
    300. Inducible nitric oxide synthase genetic polymorphism and risk of asbestosis. (PubMed id 21660141)1 Franko A....DolA3an V. (2011)
    301. Mutation in the flavin mononucleotide domain modulate s magnetic circular dichroism spectra of the iNOS ferric cyano complex in a sub strate-specific manner. (PubMed id 21718007)1 Sempombe J....Feng C. (2011)
    302. Human umbilical cord expresses several vasoactive pep tides involved in the local regulation of vascular tone: protein and gene expre ssion of Orphanin, Oxytocin, ANP, eNOS and iNOS. (PubMed id 21744319)1 Mauro A....Gerbino A. (2011)
    303. Identification of genetic factors associated with sus ceptibility to angiotensin-converting enzyme inhibitors-induced cough. (PubMed id 21052031)1 Grilo A....SA!ez M.E. (2011)
    304. Role of nitric oxide (NO) metabolism and inflammatory mediators in childhood obesity. (PubMed id 21874355)1 Hrabak A....Korner A. (2011)
    305. mRNA expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and neuronal nitric oxide synthase genes in meningitis patients. (PubMed id 21204701)1 Oztuzcu S....Cakmak E.A. (2011)
    306. Candidate genes and risk for CP: a population-based st udy. (PubMed id 21857382)1 Wu Y.W....Torres A.R. (2011)
    307. Inducible nitric-oxide synthase and nitric oxide dono r decrease insulin receptor substrate-2 protein expression by promoting proteas ome-dependent degradation in pancreatic beta-cells: involvement of glycogen syn thase kinase-3beta. (PubMed id 21700708)1 Tanioka T....Kaneki M. (2011)
    308. NOS2A as a candidate gene in Relapsing-Remitting Multi ple Sclerosis: a haplotype study using selected subsets of single nucleotide pol ymorphisms. (PubMed id 21376344)1 Manna I....Gambardella A. (2011)
    309. Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells. (PubMed id 21506111)1 Mijatovic S....Nicoletti F. (2011)
    310. Curcumin promotes degradation of inducible nitric oxi de synthase and suppresses its enzyme activity in RAW 264.7 cells. (PubMed id 21094287)1 Ben P....Yin Z. (2011)
    311. Expression of inducible nitric oxide synthase (iNOS) and period 1 (PER1) clock gene products in different sleep stages of patients w ith cognitive impairment. (PubMed id 20541418)1 Tseng I.J....Hu C.J. (2010)
    312. Reduced iNOS expression in adenoids from children wit h otitis media with effusion. (PubMed id 21073541)1 Granath A....Cardell L.O. (2010)
    313. Genetic variants in inflammation-related genes are as sociated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626)1 Hildebrandt M.A....Wu X. (2010)
    314. Analysis of single nucleotide polymorphisms in the NO S2A gene and interaction with smoking in age-related macular degeneration. (PubMed id 20374233)1 Ayala-Haedo J.A....Scott W.K. (2010)
    315. Immunohistochemical evaluation of three nitric oxide synthase isoforms in human saphenous vein exposed to different degrees of diste nsion pressures. (PubMed id 20060328)1 Viaro F....Evora P.R. (2010)
    316. Association between inducible and neuronal nitric oxi de synthase polymorphisms and recurrent depressive disorder. (PubMed id 20888049)1 GaA8ecki P....Szemraj J. (2010)
    317. Proinflammatory cytokines down-regulate intestinal se lenoprotein P biosynthesis via NOS2 induction. (PubMed id 20542496)1 Speckmann B....Steinbrenner H. (2010)
    318. Inducible nitric oxide synthase (iNOS) gene polymorph ism and disease prevalence. (PubMed id 21039732)1 Qidwai T. and Jamal F. (2010)
    319. Enhanced expression of proproliferative and antiapopt otic genes in ulcerative colitis-associated neoplasia. (PubMed id 20027603)1 Svec J....PA!cha J. (2010)
    320. Two polypyrimidine tracts in the nitric oxide synthas e 2 gene: similar regulatory sequences with different properties. (PubMed id 19669598)1 Motallebipour M....Wadelius C. (2010)
    321. Correlation between inducible nitric oxide synthase a nd cyclooxygenase-2 expression in human colorectal adenocarcinoma: a cross-sect ional study. (PubMed id 20069397)1 Habibollahi P....Ostad S.N. (2010)
    322. The expression of inducible nitric oxide synthase in the human fallopian tube during the menstrual cycle and in ectopic pregnancy. (PubMed id 19482272)1 Al-Azemi M....Ledger W. (2010)
    323. The (CCTTT)n microsatellite polymorphism in the nitri c oxide synthase 2 gene may influence bladder cancer pathogenesis. (PubMed id 20850837)1 Ryk C....de Verdier P.J. (2010)
    324. Independent predictive roles of eotaxin Ala23Thr, par aoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on car diac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients. (PubMed id 20536507)1 Wang Y....Chan J.C. (2010)
    325. Clinical significance of a myeloperoxidase gene polym orphism and inducible nitric oxide synthase expression in cirrhotic patients wi th hepatopulmonary syndrome. (PubMed id 20714866)1 Wang Y....Yang D. (2010)
    326. Involvement of Ras and AP-1 in Helicobacter pylori-in duced expression of COX-2 and iNOS in gastric epithelial AGS cells. (PubMed id 19495976)1 Cho S.O....Kim H. (2010)
    327. Polymorphisms in oxidative stress and inflammation pa thway genes, low-dose ionizing radiation, and the risk of breast cancer among U S radiologic technologists. (PubMed id 20711808)1 Schonfeld S.J....Sigurdson A.J. (2010)
    328. Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13). (PubMed id 20634424)1 Mazumdar T....Eissa N.T. (2010)
    329. Differential roles of nitric oxide synthases in regul ation of ultraviolet B light-induced apoptosis. (PubMed id 20547234)1 Liu W. and Wu S. (2010)
    330. Diabetic retinopathy: Validation study of ALR2, RAGE, iNOS and TNFB gene variants in a south Indian cohort. (PubMed id 21067489)1 Uthra S....Kumaramanickavel G. (2010)
    331. Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator. (PubMed id 20022949)1 Bui-Nguyen T.M....Kumar R. (2010)
    332. An inducible nitric oxide synthase polymorphism is as sociated with the risk of recurrent depressive disorder. (PubMed id 20869428)1 GaA8ecki P....Szemraj J. (2010)
    333. Inducible nitric oxide synthase in duodenum of childr en with Giardia lamblia infection. (PubMed id 20675273)1 Mokrzycka M....Wiszniewska B. (2010)
    334. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1 Schuurhof A....Janssen R. (2010)
    335. Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production. (PubMed id 20600019)1 Chaturvedi R....Wilson K.T. (2010)
    336. Single nucleotide polymorphisms in inflammation-relat ed genes are associated with venous thromboembolism. (PubMed id 20603037)1 Beckers M.M....Biesma D.H. (2010)
    337. A proteome-wide perspective on peroxisome targeting s ignal 1(PTS1)-Pex5p affinities. (PubMed id 20178365)1 Ghosh D. and Berg J.M. (2010)
    338. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1 Liu C.Y....Christiani D.C. (2010)
    339. Expression of inducible nitric oxide synthase (iNOS) in oral precancer and oral squamous cell carcinoma: an immunohistochemical stud y. (PubMed id 22012771)1 Varghese S.S....Madhavan R.N. (2010-2011)
    340. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1 Han S....Kang D. (2010)
    341. Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD. (PubMed id 20581851)1 Tu Y.C....Wang D.W. (2010)
    342. Gastric cancer is associated with NOS2 -954G/C polymo rphism and environmental factors in a Brazilian population. (PubMed id 20565800)1 Jorge Y.C....Silva A.E. (2010)
    343. Polymorphisms in innate immunity genes and patients r esponse to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1 Segat L....Crovella S. (2010)
    344. [The role of polymorphic variants of gene of inducibl e NO-synthase NOS2 in brain infarction in patients with acute ischemic stroke]. (PubMed id 20886685)1 Tupitsyna T.V....SlominskiA- P.A. (2010)
    345. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiat ion in rectal cancer. (PubMed id 20644561)1 Ho-Pun-Cheung A....Lopez-Crapez E. (2010)
    346. Nitric oxide synthase 2 gene polymorphisms are associ ated with prostatic volume in Korean men with benign prostatic hyperplasia. (PubMed id 20562898)1 Yoo K.H....Chang S.G. (2010)
    347. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    348. Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077)1 Ban H.J....Park K.J. (2010)
    349. Inflammation gene variants and susceptibility to albu minuria in the U.S. population: analysis in the Third National Health and Nutri tion Examination Survey (NHANES III), 1991-1994. (PubMed id 21054877)1 Ned R.M....Dowling N.F. (2010)
    350. Candidate malaria susceptibility/protective SNPs in h ospital and population-based studies: the effect of sub-structuring. (PubMed id 20459687)1 Eid N.A....Ibrahim M.E. (2010)
    351. [Expression of iNOS and HIF-1I+ with angiogenesis in a ffected skin biopsies from patients with psoriasis]. (PubMed id 20871160)1 Li Y....Wen H. (2010)
    352. Endotoxin conditioning induces VCP/p97-mediated and i nducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatas e 2A. (PubMed id 20100830)1 Ohama T. and Brautigan D.L. (2010)
    353. Genetic variations in nitric oxide synthase and argin ase influence exhaled nitric oxide levels in children. (PubMed id 21039601)1 Salam M.T....Gilliland F.D. (2010)
    354. Increased NOS2 predicts poor survival in estrogen rec eptor-negative breast cancer patients. (PubMed id 20978357)1 Glynn S.A....Ambs S. (2010)
    355. Comprehensive copy number variant (CNV) analysis of n euronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)1 Saus E....Estivill X. (2010)
    356. Simulated microgravity promotes nitric oxide-supporte d angiogenesis via the iNOS-cGMP-PKG pathway in macrovascular endothelial cells . (PubMed id 20600009)1 Siamwala J.H....Chatterjee S. (2010)
    357. The SPRY domain-containing SOCS box protein SPSB2 tar gets iNOS for proteasomal degradation. (PubMed id 20603330)1 Kuang Z....Nicholson S.E. (2010)
    358. Electron transfer in a human inducible nitric oxide s ynthase oxygenase/FMN construct co-expressed with the N-terminal globular domai n of calmodulin. (PubMed id 20868689)1 Feng C....Tollin G. (2010)
    359. Phosphorylated TP63 induces transcription of RPN13, l eading to NOS2 protein degradation. (PubMed id 20959455)1 Huang Y. and Ratovitski E.A. (2010)
    360. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1 Rajaraman P....Inskip P.D. (2010)
    361. Genetic influence on baroreflex sensitivity in normot ensive young men. (PubMed id 20300066)1 Xing-Sheng Y....Shu-Zheng L. (2010)
    362. Nitric oxide generation in children with malaria and the NOS2G-954C promoter polymorphism. (PubMed id 20811009)1 Planche T....Kremsner P.G. (2010)
    363. Genetic Risk Factors for Hepatopulmonary Syndrome in Patients With Advanced Liver Disease. (PubMed id 20346360)1 Roberts K.E....Fallon M.B. (2010)
    364. Beta-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase. (PubMed id 20228252)1 Kuhr F.K....Skidgel R.A. (2010)
    365. Regulation of the expression of inducible nitric oxid e synthase. (PubMed id 20438856)1 Pautz A....Kleinert H. (2010)
    366. Identification of fetal and maternal single nucleotid e polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1 Romero R....Menon R. (2010)
    367. A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1 Romero R....Menon R. (2010)
    368. [Significance of lipopolysaccharides, toll-like recep tor and inducible nitric oxide synthase in hepatopulmonary syndrome] (PubMed id 19953876)1 Yi H.M....Chen G.H. (2009)
    369. A far-upstream Oct-1 motif regulates cytokine-induced transcription of the human inducible nitric oxide synthase gene. (PubMed id 19467240)1 Park K.S....Geller D.A. (2009)
    370. Chagasic antibodies induce cardiac COX-2/iNOS mRNA ex pression with PGE2/NO production. (PubMed id 18579232)1 Ganzinelli S....Sterin-Borda L. (2009)
    371. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1 Shen M....Lan Q. (2009)
    372. Exhaled nitric oxide and nitric oxide synthase expres sion in Hodgkin's disease. (PubMed id 20074466)1 Guida G....Bucca C. (2009)
    373. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    374. LDL and UV-oxidized LDL induce upregulation of iNOS and NO in unstimulated J774 macrophages and HUVEC. (PubMed id 19161531)1 Persson K....Yuan X.M. (2009)
    375. Triflusal: an old drug in modern antiplatelet therapy . Review of its action, use, safety and effectiveness. (PubMed id 19465361)7 Anninos H....Vardas P. (2009)
    376. Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase. (PubMed id 19131335)1 Song W....Matalon S. (2009)
    377. Inducible nitric oxide synthase in pityriasis lichenoides lesions. (PubMed id 19220629)1 Di Giunta G....Sotto M.N. (2009)
    378. Pressure activates epidermal growth factor receptor l eading to the induction of iNOS via NFkappaB and STAT3 in human proximal tubule cells. (PubMed id 19403642)1 Broadbelt N.V....Felsen D. (2009)
    379. Inducible nitric oxide synthase deficiency impairs ma trix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic i schemia/reperfusion injury. (PubMed id 19443702)1 Hamada T....Coito A.J. (2009)
    380. Common Variants in Immune and DNA Repair Genes and Risk for Human Papillomavirus Persistence and Progression to Cervical Cancer. (PubMed id 19012493)1 Wang S.S....Hildesheim A. (2009)
    381. Extracellular activation of arginase-1 decreases ente rocyte inducible nitric oxide synthase activity during systemic inflammation. (PubMed id 19713467)1 Miki K....Delude R.L. (2009)
    382. The role of myeloperoxidase in the pathogenesis of po stoperative adhesions. (PubMed id 19614918)1 Saed G.M....Abu-Soud H.M. (2009)
    383. Role of activins and inducible nitric oxide in the pa thogenesis of ectopic pregnancy in patients with or without Chlamydia trachomat is infection. (PubMed id 19692623)1 Refaat B....Ledger W. (2009)
    384. Hypoxia regulates iNOS expression in human normal peritoneal and adhesion fibroblasts through nuclear factor kappa B activation mechanism. (PubMed id 18281043)1 Jiang Z.L....Saed G.M. (2009)
    385. Two synthetic peptides corresponding to the proximal heme-binding domain and CD1 domain of human endothelial nitric-oxide synthase i nhibit the oxygenase activity by interacting with CaM. (PubMed id 19358819)1 Chen P.F. and Wu K.K. (2009)
    386. NOS2A, TLR4, and IFNGR1 interactions influence pulmon ary tuberculosis susceptibility in African-Americans. (PubMed id 19575238)1 Velez D.R....Scott W.K. (2009)
    387. Zinc protoporphyrin inhibition of lipopolysaccharide- , lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination. (PubMed id 19376148)1 Chow J.M....Chen Y.C. (2009)
    388. Effect of UVA irradiation on proliferation and NO/iNO S system of human skin fibroblast. (PubMed id 19734575)1 Chen M....Chen X. (2009)
    389. Nitrosative stress and inducible nitric oxide synthas e expression in periventricular leukomalacia. (PubMed id 19415311)1 Haynes R.L....Kinney H.C. (2009)
    390. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (2009)
    391. NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma. (PubMed id 18668140)1 Uffort D.G....Ellerhorst J.A. (2009)
    392. Clinorotation upregulates inducible nitric oxide synt hase by inhibiting AP-1 activation in human umbilical vein endothelial cells. (PubMed id 19306295)1 Wang Y.C....Sun X.Q. (2009)
    393. Pivotal role of c-Fos in nitric oxide synthase 2 expression in airway epithelial cells. (PubMed id 19135542)1 Chambellan A....Erzurum S.C. (2009)
    394. [Time-order expression of caspase-3 and iNOS in contu sed human brain tissue] (PubMed id 19788069)1 Cai H.X....Yin W.J. (2009)
    395. Is apoptosis the cause of noninsertional achilles ten dinopathy? (PubMed id 19741110)1 Pearce C.J....Calder J.D. (2009)
    396. Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay. (PubMed id 19028820)1 Greisenegger S....Mannhalter C. (2009)
    397. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. (PubMed id 18936436)1 Chang M.H....Khoury M.J. (2009)
    398. A critical role for CHIP in the aggresome pathway. (PubMed id 18955503)1 Sha Y....Eissa N.T. (2009)
    399. Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1. (PubMed id 19074427)1 Pautz A....Kleinert H. (2009)
    400. Inducible and endothelial nitric oxide synthase expre ssion in human atherogenesis: an immunohistochemical and ultrastructural study. (PubMed id 18835789)1 Perrotta I....Cassese M. (2009)
    401. Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. (PubMed id 19141999)4 Giedraitis V....Glaser A. (2009)
    402. Biochemistry of soluble guanylate cyclase. (PubMed id 19089323)1 Derbyshire E.R. and Marletta M.A. (2009)
    403. [Relationship between expression of inducible nitric oxide synthase in nasal mucosa and outcome after endoscopic sinus surgery]. (PubMed id 18476605)1 Lin L....Zheng Y. (2008)
    404. Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. (PubMed id 18510611)1 Ikeda S....Tsugane S. (2008)
    405. Global gene expression patterns and induction of innate immune response in human laryngeal epithelial cells in response to Acinetobacter baumannii outer membrane protein A. (PubMed id 18625015)1 Kim S.A....Lee J.C. (2008)
    406. Genetic polymorphisms in mediators of inflammation and gastric precancerous lesions. (PubMed id 18287876)1 Canzian F....Kato I. (2008)
    407. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1 Starr J.M....Deary I.J. (2008)
    408. Long-term survival after ischemic stroke in postmenopausal women is affected by an interaction between smoking and genetic variation in nitric oxide synthases. (PubMed id 18648197)1 Oksala N.K....Karhunen P.J. (2008)
    409. Inhibition of inducible nitric-oxide synthase protects human T cells from hypoxia-induced apoptosis. (PubMed id 18079278)1 Kiang J.G....Li Y. (2008)
    410. Nitric oxide synthase isoforms and NF-kappaB activity in normal and osteoarthritic human chondrocytes: regulation by inducible nitric oxide. (PubMed id 18675932)1 Rosa S.C....Mendes A.F. (2008)
    411. Family-based association study between NOS-I and -IIA polymorphisms and autism spectrum disorders in Korean trios. (PubMed id 18563708)1 Kim H.W....Yoo H.J. (2008)
    412. Genetic profiling of genes from the oxidative stress pathway among North and South Indians. (PubMed id 18720901)1 Tiwari A.K....Thelma B.K. (2008)
    413. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. (PubMed id 19096157)1 Colton C.A....Vitek M.P. (2008)
    414. Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils. (PubMed id 19178812)1 Lukes P....Astl J. (2008)
    415. Novel noncoding antisense RNA transcribed from human anti-NOS2A locus is differentially regulated during neuronal differentiation of embryonic stem cells. (PubMed id 18820242)1 Korneev S.A....O'Shea M. (2008)
    416. Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. (PubMed id 18676870)1 Hsing A.W....Chanock S.J. (2008)
    417. CXCL12 induction of inducible nitric oxide synthase in human CD8 T cells. (PubMed id 19059114)1 Choy J.C....Pober J.S. (2008)
    418. Mitochondrial localization of nitric oxide synthase in partially differentiated urothelial cells of urinary bladder lesions. (PubMed id 18301246)1 Romih R....Jezernik K. (2008)
    419. Overexpression of inducible nitric oxide synthase and accumulation of 8-OHdG in nasopharyngeal carcinoma. (PubMed id 18184270)1 Segawa Y....Tsuneyoshi M. (2008)
    420. Inducible nitric oxide synthase and histopathological correlation in chronic viral hepatitis. (PubMed id 17553719)1 Atik E....Doran F. (2008)
    421. Identification of critical amino acid residues for human iNOS functional activity. (PubMed id 18459037)1 Naureckiene S....Chanda P.K. (2008)
    422. Doppler analysis and placental nitric oxide synthase expression during fetal growth restriction. (PubMed id 18828052)1 Giannubilo S.R....Tranquilli A.L. (2008)
    423. iNOS gene silencing prevents inflammatory cytokine-induced beta-cell apoptosis. (PubMed id 18217711)1 Li F. and Mahato R.I. (2008)
    424. Expression of nitric oxide synthases and endogenous NO metabolism in bronchopulmonary dysplasia. (PubMed id 18500734)1 Davis C.W....Gow A.J. (2008)
    425. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1 Lu Y....Boer J.M. (2008)
    426. High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression. (PubMed id 18279675)1 Takamiya R....Perrella M.A. (2008)
    427. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1 Hosgood H.D....Lan Q. (2008)
    428. Expression of inducible nitric oxide synthase and nitric oxide-modified proteins in Helicobacter pylori-associated atrophic gastric mucosa. (PubMed id 19120907)1 Naito Y....Yoshikawa T. (2008)
    429. Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. (PubMed id 18774388)1 Tremblay K....Laprise C. (2008)
    430. Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis. (PubMed id 18597705)1 Tortorici S....Tete S. (2008)
    431. Metabolic profile and nitric oxide synthase expression of skeletal muscle fibers are altered in patients with type 1 diabetes. (PubMed id 18465682)1 Fritzsche K....Punkt K. (2008)
    432. 5-aminosalicylic acid improves indomethacin-induced e nteropathy by inhibiting iNOS transcription in rats. (PubMed id 17503181)7 Nandi J....Levine R.A. (2008)
    433. Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation. (PubMed id 18753139)1 Marjanovic J.A....Du X. (2008)
    434. Sildenafil citrate attenuates a complex maze impairme nt induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitr o-L-arginine methyl ester. (PubMed id 17362916)7 Devan B.D....Ingram D.K. (2007)
    435. Alveolar macrophages from normal subjects lack the NOS-related system y+ for arginine transport. (PubMed id 17363779)7 Rotoli B.M....Bussolati O. (2007)
    436. A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis. (PubMed id 17475563)1 Gomez L.M....Martin J. (2007)
    437. NOS2 regulation of NF-kappaB by S-nitrosylation of p65. (PubMed id 17720813)1 Kelleher Z.T....Marshall H.E. (2007)
    438. Population genetic data on four STR loci, PAI (CA)n, GpIIIa (CT)n, PLAT (TG)14 (CA)12, and NOS2A (CCTTT)n, in Mediterranean populations. (PubMed id 17320454)1 Falchi A....Varesi L. (2007)
    439. Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells. (PubMed id 17855767)1 Uno K....Yoshimura T. (2007)
    440. Intralesional expression of mRNA of interferon- gamma , tumor necrosis factor- alpha , interleukin-10, nitric oxide synthase, indoleamine-2,3-dioxygenase, and RANTES is a major immune effector in Mediterranean spotted fever rickettsiosis. (PubMed id 17674321)1 de Sousa R....Walker D.H. (2007)
    441. Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population. (PubMed id 17355643)1 Huang H.Y....Helzlsouer K.J. (2007)
    442. Inducible nitric oxide synthase expression is upregulated in oral submucous fibrosis. (PubMed id 17687170)1 Rajendran R. and Varkey S. (2007)
    443. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1 Harris S.E....Deary I.J. (2007)
    444. Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes. (PubMed id 18050214)1 Chockalingam P.S....Majumdar M.K. (2007)
    445. Regulation of the murine inducible nitric oxide synth ase gene by dexamethasone involves a heterogeneous nuclear ribonucleoprotein I (hnRNPI) dependent pathway. (PubMed id 17379310)7 SAPderberg M....Lang M.A. (2007)
    446. Genetic polymorphisms associated with priapism in sickle cell disease. (PubMed id 17408468)1 Elliott L....Telen M.J. (2007)
    447. [Expression and significance of HIF-1alpha and iNOS in human middle ear cholesteatoma epithelium] (PubMed id 17650819)1 Zhang E. and Gong S. (2007)
    448. Genetic polymorphisms of macrophage-mediators in Guillain-Barre syndrome. (PubMed id 17761309)1 Geleijns K....Jacobs B.C. (2007)
    449. [Effects of EPA, DHA on the secretion of NO, expressi on of iNOS mRNA and DNA-binding activity of NFkappaB in human monocyte] (PubMed id 17953212)1 Xia Y....Su Y. (2007)
    450. Nitric oxide synthase induction and cytotoxic nitrogen-related oxidant formation in conjunctival epithelium of dry eye (Sjogren's syndrome). (PubMed id 17600738)1 Cejkova J....Brunova B. (2007)
    451. Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase. (PubMed id 17322004)1 Korhonen R....Kleinert H. (2007)
    452. Homocysteine and asymmetric dimethylarginine (ADMA): biochemically linked but differently related to vascular disease in chronic kid ney disease. (PubMed id 17937610)7 van Guldener C....Stehouwer C.D. (2007)
    453. Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans. (PubMed id 17240318)1 Rodway G.W....Sanders M.H. (2007)
    454. Genetic polymorphisms in alveolar macrophage response-related genes, and risk of silicosis and pulmonary tuberculosis in Chinese iron miners. (PubMed id 17223386)1 Qu Y....Xia Z. (2007)
    455. Nitric oxide synthase and superoxide dismutase gene polymorphisms in Behcet disease. (PubMed id 17296902)1 Nakao K....Sakamoto T. (2007)
    456. Different expression of NOS isoforms in early endothelial progenitor cells derived from peripheral and cord blood. (PubMed id 17492662)1 Muscari C....Guarnieri C. (2007)
    457. No association between Parkinson's disease and three polymorphisms in the eNOS, nNOS, and iNOS genes. (PubMed id 17174475)1 Huerta C....Alvarez V. (2007)
    458. The NOS3 (27-bp repeat, intron 4) polymorphism is associated with susceptibility to osteomyelitis. (PubMed id 16889995)1 Asensi V....Celada A. (2007)
    459. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. (PubMed id 17908769)1 Emonts M....Sanders E.A. (2007)
    460. Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11. (PubMed id 17928287)1 Berg D.T....Grinnell B.W. (2007)
    461. [Influence of iNOS silencing by RNA interference on p roliferation activity of Tca8113 cell] (PubMed id 18070432)1 Yang L....Shao J. (2007)
    462. Skeletal muscle neuronal nitric oxide synthase micro protein is reduced in people with impaired glucose homeostasis and is not normalized by exercise training. (PubMed id 17884453)1 Bradley S.J....McConell G.K. (2007)
    463. Limited availability of L-arginine increases DNA-bind ing activity of NF-kappaB and contributes to regulation of iNOS expression. (PubMed id 17340133)7 Kagemann G....Schnorr O. (2007)
    464. iNOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis. (PubMed id 17233833)1 Hoki Y....Kawanishi S. (2007)
    465. Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase. (PubMed id 17940019)1 Hasselblatt P....Wagner E.F. (2007)
    466. Genetic polymorphisms and spontaneous preterm birth. (PubMed id 17267840)1 Gibson C.S....Nelson K.B. (2007)
    467. Expression of NOS and HIF-1alpha in human colorectal carcinoma and implication in tumor angiogenesis. (PubMed id 16937436)1 Yu J.X....Ma H.Y. (2006)
    468. Comprehensive association analysis of the NOS2A gene with Parkinson disease. (PubMed id 17159127)1 Schulte C....Gasser T. (2006)
    469. N-terminal palmitoylation within the appropriate amino acid environment conveys on NOS2 the ability to progress along the intracellular sorting pathways. (PubMed id 16569659)1 Navarro-Lerida I....Rodriguez-Crespo I. (2006)
    470. Triflusal: an antiplatelet drug with a neuroprotectiv e effect? (PubMed id 16939630)7 GonzA!lez-Correa J.A. and De La Cruz J.P. (2006)
    471. NF-kappaB activity and iNOS expression in monocytes from internal jugular blood of migraine without aura patients during attacks. (PubMed id 16919057)1 Sarchielli P....Calabresi P. (2006)
    472. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    473. Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma. (PubMed id 16543247)1 Wang S.S....Rothman N. (2006)
    474. Nitric oxide-dependent negative feedback of PARP-1 trans-activation of the inducible nitric-oxide synthase gene. (PubMed id 16464859)1 Yu Z....Kone B.C. (2006)
    475. Involvement of endogenous nitric oxide in the regulation of K+ channel activity in cultured human proximal tubule cells. (PubMed id 17062169)1 Nakamura K....Kubokawa M. (2006)
    476. [Restraint stress down-regulates L-Arg/NOS/NO pathway of platelet and aortic intima in rats] (PubMed id 16778961)7 Cui Y.Y....Geng B. (2006)
    477. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
    478. Up-regulation of Fas expression by Pseudomonas aeruginosa-infected endothelial cells depends on modulation of iNOS and enhanced production of NO induced by bacterial type III secreted proteins. (PubMed id 16820946)1 Assis M.C....Plotkowski M.C. (2006)
    479. Inducible nitric oxide synthase polymorphism is associated with the increased risk of differentiated gastric cancer in a Japanese population. (PubMed id 17072962)1 Goto Y....Hamajima N. (2006)
    480. Characterization of NO and cytokine production in immune-activated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background. (PubMed id 16771679)1 Vitek M.P....Colton C.A. (2006)
    481. Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm. (PubMed id 16574921)1 Mineharu Y....Koizumi A. (2006)
    482. Astrocytic-inducible nitric oxide synthase in the ischemic developing human brain. (PubMed id 17065568)1 Askalan R....Hawkins C. (2006)
    483. Gene expression changes in SNAP-stimulated and iNOS-transfected tenocytes--expression of extracellular matrix genes and its implications for tendon-healing. (PubMed id 16865710)1 Molloy T.J....Murrell G.A. (2006)
    484. 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion. (PubMed id 16290060)1 Ma N....Kawanishi S. (2006)
    485. Involvement of Syk kinase in TNF-induced nitric oxide production by airway epithelial cells. (PubMed id 17070777)1 Ulanova M....Befus A.D. (2006)
    486. Inducible nitric oxide synthase and apoptosis in human B cell lymphomas. (PubMed id 16924421)1 Atik E....Tuncer I. (2006)
    487. [Effect of urotensin II on iNOS expression in human um bilical vein endothelial cells]. (PubMed id 21158070)1 Xu D. and Liu C.H. (2006)
    488. Pulmonary nitric oxide synthases and nitrotyrosine: findings during lung development and in chronic lung disease of prematurity. (PubMed id 16950998)1 Sheffield M....Truog W.E. (2006)
    489. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
    490. The polypyrimidine tract-binding protein (PTB) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression. (PubMed id 16950790)1 Pautz A....Kleinert H. (2006)
    491. [Relationship between expression of inducible nitric oxide synthase and proliferative potency of endothelium in hemangioma in infant s] (PubMed id 16573167)1 Li J.S....Cheng H.L. (2006)
    492. NOS2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activity. (PubMed id 16813666)1 Kawaguchi Y....Kamatani N. (2006)
    493. [The relationship between resting heart rate and single nucleotide polymorphism at 3 sites of nitric oxide synthase gene in the Chinese Han nationality population] (PubMed id 17160951)1 Ma H.X....Xie Z.X. (2006)
    494. NOS2A and the modulating effect of cigarette smoking in Parkinson's disease. (PubMed id 16823855)1 Hancock D.B....Scott W.K. (2006)
    495. Expression of nitric oxide synthases in parathyroid gland adenoma and parathyroid gland hyperplasia. (PubMed id 16136006)1 Kucera T....Astl J. (2005)
    496. Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction. (PubMed id 15784171)1 Heltianu C....Simionescu M. (2005)
    497. Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. (PubMed id 16211247)1 Chiarini A....Armato U. (2005)
    498. Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion. (PubMed id 16195370)1 Barrier A....Lemoine A. (2005)
    499. Analysis of polymorphic sites in the promoter of the nitric oxide synthase 2 gene. (PubMed id 16105645)1 Coia V....Kun J.F. (2005)
    500. The RNA binding protein TIAR is involved in the regulation of human iNOS expression. (PubMed id 16191398)1 Fechir M....Kleinert H. (2005)
    501. A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. (PubMed id 16352737)1 Flores-Villanueva P.O.... Granados J. (2005)
    502. Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. (PubMed id 16126846)1 Linker K....Kleinert H. (2005)
    503. Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples. (PubMed id 15654505)1 Liu Y....Tsugane S. (2005)
    504. The promoter of inducible nitric oxide synthase implicated in glaucoma based on genetic analysis and nuclear factor binding. (PubMed id 16288199)1 Motallebipour M....Wadelius C. (2005)
    505. Expression of mRNA for inducible NO synthase in human brain. (PubMed id 16282997)1 Smolina I.V....Rasskazov V.A. (2005)
    506. Association of a functional inducible nitric oxide synthase promoter variant with susceptibility to biopsy-proven giant cell arteritis. (PubMed id 16265698)1 Gonzalez-Gay M.A....Martin J. (2005)
    507. Inducible nitric oxide synthase polymorphism is associated with susceptibility to Henoch-Schonlein purpura in northwestern Spain. (PubMed id 15940772)1 Martin J....Gonzalez-Gay M.A. (2005)
    508. Nitric oxide synthase 2 (NOS2) promoter polymorphisms in colorectal cancer. (PubMed id 15922861)1 Fransen K....Soderkvist P. (2005)
    509. Expression of inducible nitric oxide synthase in human cutaneous leishmaniasis. (PubMed id 16311916)1 Serarslan G. and Atik E. (2005)
    510. Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells. (PubMed id 15631944)1 Cui Z....Baydoun A.R. (2005)
    511. Intragraft iNOS induction during human liver allograft rejection depresses cytochrome p450 activity. (PubMed id 15349722)1 Westerholt A....Heidecke C.D. (2004)
    512. Inducible nitric oxide synthase gene (NOS2A) haplotypes and the outcome of hepatitis C virus infection. (PubMed id 14985675)1 Yee L.J....Thursz M.R. (2004)
    513. Differential expression of nitric oxide synthases (NOS 1-3) in human skeletal muscle following exercise countermeasure during 12 weeks of bed rest. (PubMed id 15180967)1 Rudnick J....Blottner D. (2004)
    514. Antioxidant protection from HIV-1 gp120-induced neuroglial toxicity. (PubMed id 15285794)1 Walsh K.A....Hammond R.R. (2004)
    515. The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage. (PubMed id 15054088)7 Fogli S....Breschi M.C. (2004)
    516. Relaxin potentiates the expression of inducible nitric oxide synthase by endothelial cells from human umbilical vein in in vitro culture. (PubMed id 15026539)1 Quattrone S....Bani D. (2004)
    517. Host polymorphisms and the incidence of malaria in Ugandan children. (PubMed id 15642965)1 Parikh S....Rosenthal P.J. (2004)
    518. iNOS promoter variants and severe malaria in Ghanaian children. (PubMed id 15482399)1 Cramer J.P....Bienzle U. (2004)
    519. Monosodium urate crystals synergize with IFN-gamma to generate macrophage nitric oxide: involvement of extracellular signal-regulated kinase 1/2 and NF-kappa B. (PubMed id 15100320)1 Jaramillo M....Olivier M. (2004)
    520. [Polymorphism of NOS2A promoter -969(G>C) is associated with portal hypertension of liver cirrhosis.] (PubMed id 15583989)1 Cheng Y.Q....Jiang X.D. (2004)
    521. Thermodynamics of oxidation-reduction reactions in mammalian nitric-oxide synthase isoforms. (PubMed id 14715665)1 Gao Y.T....Salerno J.C. (2004)
    522. Down-regulation of inducible nitric oxide synthase by lysophosphatidic acid in human respiratory epithelial cells. (PubMed id 15532709)1 Kadowaki S....Shimizu E. (2004)
    523. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    524. Inducible NO synthase inhibits the growth of free tumor cells, but enhances the growth of solid tumors. (PubMed id 15205363)1 Nishikawa M....Inoue M. (2004)
    525. Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men. (PubMed id 15494775)1 Imamura A....Murohara T. (2004)
    526. Enhanced iNOS expression in leukocytes and circulating endothelial cells is associated with the progression of coronary artery lesions in acute Kawasaki disease. (PubMed id 14764920)1 Yu X....Miyawaki T. (2004)
    527. Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line. (PubMed id 15492785)1 Lahiri M. and Martin J.H. (2004)
    528. Relation of hypoxia-inducible factor-1alpha to vascular endothelial growth factor and vasoactive factors during healing of gastric ulcers. (PubMed id 15838334)1 Hashimoto H....Yamashito K. (2004)
    529. Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells. (PubMed id 15271950)1 Keller C.C....Perkins D.J. (2004)
    530. Inducible nitric oxide synthase promoter polymorphism in human brucellosis. (PubMed id 14623011)1 Orozco G....Martin J. (2003)
    531. Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans. (PubMed id 12508391)1 Oates J.C....Gilkeson G.S. (2003)
    532. Inducible and endothelial constitutive nitric oxide synthase gene polymorphisms in Kawasaki disease. (PubMed id 12709136)1 Khajoee V....Hara T. (2003)
    533. Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population. (PubMed id 12768436)1 Lee J.K....Jo I. (2003)
    534. Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease. (PubMed id 12816735)1 Barreiro E....Hussain S.N. (2003)
    535. Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. (PubMed id 12948935)1 Kreiselmeier N.E....Kelley T.J. (2003)
    536. Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. (PubMed id 14740870)1 Boutlis C.S....Anstey N.M. (2003)
    537. Induction of nitric oxide synthase in RAW 264.7 macrophages by lipoteichoic acid from Staphylococcus aureus: involvement of protein kinase C- and nuclear factor-kB-dependent mechanisms. (PubMed id 12607534)1 Kuo C.T....Lin C.H. (2003)
    538. Hepatitis C virus core protein transactivates the inducible nitric oxide synthase promoter via NF-kappaB activation. (PubMed id 14638407)1 de Lucas S....Carreno V. (2003)
    539. Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. (PubMed id 14634838)1 Yoshimura K....Tsugane S. (2003)
    540. Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren. (PubMed id 12641410)1 Mombo L.E....Krishnamoorthy R. (2003)
    541. Haplotypic relationship between SNP and microsatellite markers at the NOS2A locus in two populations. (PubMed id 14551604)1 Burgner D....Kwiatkowski D.P. (2003)
    542. Increased inducible nitric oxide synthase expression and nitric oxide concentration in patients with aplastic anemia. (PubMed id 12601489)1 Chung I.J....Kim H.J. (2003)
    543. The inducible nitric oxide synthase promoter polymorphism does not confer susceptibility to systemic lupus erythematosus. (PubMed id 12509623)1 Lopez-Nevot M.A....Martin J. (2003)
    544. Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase. (PubMed id 12855682)1 Yoshida M. and Xia Y. (2003)
    545. Inducible nitric oxide synthase (NOS II) is constitutive in human neutrophils. (PubMed id 14616549)1 Cedergren J....Skogh T. (2003)
    546. Hypoxia inactivates inducible nitric oxide synthase in mouse macrophages by disrupting its interaction with alpha-actinin 4. (PubMed id 12960352)1 Daniliuc S....Nitza L. (2003)
    547. A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. (PubMed id 12732844)1 Watanabe I....Koga T. (2003)
    548. No significant correlation exists between nitric oxide production and apoptosis in myelodysplastic syndromes. (PubMed id 12486325)1 Choi J.W. (2003)
    549. Expression of nitric oxide synthase isoforms in the human placenta is not altered by labor. (PubMed id 14614209)1 Kakui K....Fujii S. (2003)
    550. STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation. (PubMed id 12788789)1 Xu W....Erzurum S.C. (2003)
    551. Undetectable levels of tumor necrosis factor-alpha, nitric oxide and inadequate expression of inducible nitric oxide synthase in congenital hypothyroidism. (PubMed id 12799216)1 Rodriguez-Arnao M.D....Munoz-Fernandez M.A. (2003)
    552. Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children. (PubMed id 12631094)1 Valles P.G....Ruttler M. (2003)
    553. Fire ant venom alkaloid, isosolenopsin A, a potent an d selective inhibitor of neuronal nitric oxide synthase. (PubMed id 12745988)7 Yi G.B....Rockhold R.W. (2003)
    554. In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits. (PubMed id 12690222)1 Zanetti M....O'Brien T. (2003)
    555. Activation of epidermal growth factor receptor signals induction of nitric oxide synthase-2 in human optic nerve head astrocytes in glaucomatous optic neuropathy. (PubMed id 12828935)1 Liu B. and Neufeld A.H. (2003)
    556. Helicobacter pylori infection activates NF-kappaB signaling pathway to induce iNOS and protect human gastric epithelial cells from apoptosis. (PubMed id 12919943)1 Kim J.M....Song I.S. (2003)
    557. Intracellular formation of 'undisruptable' dimers of inducible nitric oxide synthase. (PubMed id 14614131)1 Kolodziejski P.J....Eissa N.T. (2003)
    558. A critical role for C/EBPbeta binding to the AABS promoter response element in the human iNOS gene. (PubMed id 12958187)1 Guo Z....Geller D.A. (2003)
    559. Prostacyclin enhances the expression of LPS/INF-gamma-induced nitric oxide synthase in human monocytes. (PubMed id 12119468)1 Plum J....Meyer-Kirchrath J. (2002)
    560. No evidence for association of the inducible nitric oxide synthase promoter polymorphism with Trypanosoma cruzi infection. (PubMed id 12135432)1 Calzada J.E....Martin J. (2002)
    561. Expression of nitric oxide synthase isoforms in human pregnant myometrium at term. (PubMed id 12445599)1 Bao S....Schreiber J. (2002)
    562. IL-15 up-regulates iNOS expression and NO production by gingival epithelial cells. (PubMed id 12237122)1 Yanagita M....Murakami S. (2002)
    563. Inducible nitric oxide synthase expression in chronic viral hepatitis and its relation with histological severity of disease. (PubMed id 12431203)1 Kandemir O....Kaya A. (2002)
    564. Nitric oxide synthase-cyclooxygenase interactions are involved in tumor cell angiogenesis and migration. (PubMed id 12462194)1 Davel L....Sales M.E. (2002)
    565. Systemic nitric oxide production in human malaria. II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen expression. (PubMed id 12125143)1 Saunders J.R....Anstey N.M. (2002)
    566. Expression of inducible nitric oxide synthase in skin lesions of patients with american cutaneous leishmaniasis. (PubMed id 12117977)1 Qadoumi M....Bogdan C. (2002)
    567. Detection of iNOS gene expression in cutaneous leishmaniasis biopsy tissue. (PubMed id 11985871)1 Arevalo I....Matlashewski G. (2002)
    568. [A short tandem repeat polymorphism in the inducible nitric oxide synthase gene in Chinese population] (PubMed id 11985259)1 Lu X....Zheng X.F. (2002)
    569. Immunolocalization of inducible nitric oxide synthase in localized juvenile periodontitis patients. (PubMed id 12489192)1 Gaspirc B....Skaleric U. (2002)
    570. Correlation between nitric oxide and cyclooxygenase-2 pathways in head and neck squamous cell carcinomas. (PubMed id 12459168)1 Gallo O....Franchi A. (2002)
    571. Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-kappa B- repressing factor (NRF) in basal repression of the hiNOS gene. (PubMed id 12381793)1 Feng X....Geller D.A. (2002)
    572. Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. (PubMed id 12167619)1 Liu X....Pahan K. (2002)
    573. TTD: Therapeutic Target Database. (PubMed id 11752352)7 Chen X....Chen Y.Z. (2002)
    574. Inducible nitric oxide synthase gene and diabetic retinopathy in Asian Indian patients. (PubMed id 12081717)1 Kumaramanickavel G....Sharma T. (2002)
    575. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    576. PKC-zeta prevents oxidant-induced iNOS upregulation and protects the microtubules and gut barrier integrity. (PubMed id 12223351)1 Banan A....Keshavarzian A. (2002)
    577. Peroxisomal localization of inducible nitric oxide syn thase in hepatocytes. (PubMed id 12085352)1 Stolz D.B....Watkins S.C. (2002)
    578. Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide. (PubMed id 12060397)1 Fecker L.F....Geilen C.C. (2002)
    579. Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. (PubMed id 11907646)1 Morris B.J....Wang L. (2002)
    580. Analysis of nitric oxide synthase genes in cluster headache. (PubMed id 12421162)1 Sjostrand C....Hillert J. (2002)
    581. Citrulline is not the major product using the standar d 'NOS activity' assay on renal cortical homogenates. (PubMed id 11742852)7 Conrad K.P....Novak J. (2002)
    582. Endothelial nitric oxide synthase and caveolin-1 are co-localized in sinusoidal endothelial fenestrae. (PubMed id 11422783)1 Yokomori H....Ishii H. (2001)
    583. No evidence for involvement of the human inducible nitric oxide synthase (iNOS) gene in susceptibility to typical migraine. (PubMed id 11424980)1 Lea R.A....Griffiths L.R. (2001)
    584. Influence of an inducible nitric oxide synthase promoter variant on clinical variables in patients with coronary artery disease. (PubMed id 11294696)1 Morris B.J....Wang X.L. (2001)
    585. No linkage or association of the nitric oxide synthase genes to multiple sclerosis. (PubMed id 11525805)1 Modin H....Hillert J. (2001)
    586. The specific NOS2 inhibitor, 1400W, sensitizes HepG2 cells to genotoxic, oxidative, xenobiotic, and endoplasmic reticulum stresses. (PubMed id 11761338)1 Payne C.M....Garewal H. (2001)
    587. Nitric oxide synthase 2(Lambarene) (G-954C), increased nitric oxide production, and protection against malaria. (PubMed id 11443559)1 Kun J.F....Kremsner P.G. (2001)
    588. [Abnormal expression of p53, Ki67 and iNOS in human esophageal carcinoma in situ and pre-malignant lesions] (PubMed id 11783017)1 Jin Y....Liu B. (2001)
    589. Linkage of the human inducible nitric oxide synthase gene to type 1 diabetes. (PubMed id 11397889)1 Johannesen J....Nerup J. (2001)
    590. Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol. (PubMed id 11579140)1 Bruce-Keller A.J....Nath A. (2001)
    591. Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages. (PubMed id 11457725)1 Kuncewicz T....Kone B.C. (2001)
    592. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (2000)
    593. Citrulline immunohistochemistry for demonstration of NOS activity in vivo and in vitro. (PubMed id 10944418)7 Keilhoff G....Wolf G. (2000)
    594. Increased oxidative stress with gene alteration in urinary bladder urothelium after the Chernobyl accident. (PubMed id 10842192)1 Romanenko A....Fukushima S. (2000)
    595. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. (PubMed id 11022011)4 Ober C....Cox N.J. (2000)
    596. Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. (PubMed id 11050162)1 Hussain S.P....Harris C.C. (2000)
    597. A 4-trifluoromethyl derivative of salicylate, triflusal, stimulates nitric oxide production by human neutrophils: role in platelet function. (PubMed id 10998082)7 De Miguel L.S....FarrAc A.L. (2000)
    598. Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. (PubMed id 11114180)1 Felley-Bosco E....Quest A.F. (2000)
    599. Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS. (PubMed id 10203575)1 Adamson D.C....Dawson V.L. (1999)
    600. Nitric oxide: discovery and impact on clinical medicine. (PubMed id 10450191)1 Moncada S. (1999)
    601. Expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions. (PubMed id 9916929)1 Facchetti F....Badolato R. (1999)
    602. Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity. (PubMed id 9870939)1 Adamson D.C....Dawson V.L. (1999)
    603. Human immunodeficiency virus infection, inducible nitric oxide synthase expression, and microglial activation: pathogenetic relationship to the acquired immunodeficiency syndrome dementia complex. (PubMed id 10443886)1 Rostasy K....Navia B.A. (1999)
    604. Human immunodeficiency virus type 1 Tat protein stimulates inducible nitric oxide synthase expression and nitric oxide production in microglial cultures. (PubMed id 10446807)1 Polazzi E....Minghetti L. (1999)
    605. Measurement of NOS activity by conversion of radiolab eled arginine to citrulline using ion-exchange separation. (PubMed id 10906994)7 Knowles R.G. and Salter M. (1998)
    606. Comparison of in vitro effects of triflusal and acety salicylic acid on nitric oxide synthesis by human neutrophils. (PubMed id 9551715)7 SA!nchez de Miguel L....LA^pez-FarrAc A. (1998)
    607. Radiochemical measurement of NOS activity by conversi on of [14C]L-arginine to citrulline using HPLC separation. (PubMed id 10906995)7 Cunningham J.M. and Rayne R.C. (1998)
    608. Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. (PubMed id 9333325)7 VA!squez-Vivar J....Kalyanaraman B. (1997)
    609. Molecular cloning and structural organization of the human inducible nitric oxide synthase gene (NOS2). (PubMed id 8645258)1 Xu W....Emson P. (1996)
    610. Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. (PubMed id 8943206)1 Adamson D.C....Dawson V.L. (1996)
    611. The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line. (PubMed id 8760410)1 Barton C.H....Mann D.A. (1996)
    612. Inhibition of endothelial nitric oxide synthase by cy tochrome P-450 reductase inhibitors. (PubMed id 7536941)7 Dudek R.R....Suzuki H. (1995)
    613. The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen. (PubMed id 7544003)1 Vouldoukis I....Mossalayi M.D. (1995)
    614. Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. (PubMed id 7509810)1 Chartrain N.A....Mudgett J.S. (1994)
    615. The basic domain of the lentiviral Tat protein is responsible for damages in mouse brain: involvement of cytokines. (PubMed id 7526541)1 Philippon V....Filippi P. (1994)
    616. Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11.2-q12. (PubMed id 7514565)1 Marsden P.A....Hall A.V. (1994)
    617. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. (PubMed id 7528106)1 Mannick J.B.... Stamler J.S. (1994)
    618. Effect of anti-fungal imidazoles on mRNA levels and e nzyme activity of inducible nitric oxide synthase. (PubMed id 7518297)7 Bogle R.G....Vallance P. (1994)
    619. Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. (PubMed id 8383325)1 Corbett J.A....McDaniel M.L. (1993)
    620. The dual mode of inhibition of calmodulin-dependent n itric-oxide synthase by antifungal imidazole agents. (PubMed id 7683652)7 Wolff D.J....Samatovicz R.A. (1993)
    621. Natural antisense transcript stabilizes inducible nitric oxide synthase messenger RNA in rat hepatocytes. (PubMed id 18161049)9 Matsui K....Okumura T. (2008)
    622. Role of cyclooxygenase-2 and inducible nitric oxide synthase in pancreatic cancer. (PubMed id 12164968)9 Kong G....Rhee J.C. (2002)
    623. Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in human brain tumors: relationships of iNOS to superoxide dismutase (SOD) proteins (SOD1 and SOD2), Ki-67 antigen (MIB-1) and p53 protein. (PubMed id 12624786)9 Kato S....Ohama E. (2003)
    624. Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway. (PubMed id 11312270)9 Musial A. and Eissa N.T. (2001)
    625. Inducible nitric oxide synthase expression in various laryngeal lesions in relation to carcinogenesis, angiogenesis, and patients' prognosis. (PubMed id 17712678)9 Shigyo H....Harabuchi Y. (2007)
    626. Inducible nitric oxide synthase (iNOS) expression and its prognostic value in prostate cancer. (PubMed id 11712818)9 Aaltoma S.H....Kosma V.M. (2001)
    627. Liver infiltrating T lymphocytes express interferon gamma and inducible nitric oxide synthase in chronic hepatitis C virus infection. (PubMed id 10644322)9 Schweyer S....Fayyazi A. (2000)
    628. [Expression of endothelial nitric oxide synthase and inducible nitric oxide synthase in synovium of rheumatoid arthritis] (PubMed id 10614169)9 Ishiuchi N....Asano G. (1999)
    629. Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine. (PubMed id 9115299)9 Melillo G....Varesio L. (1997)
    630. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. (PubMed id 7542498)9 Weinberg J.B....Bachus K.E. (1995)
    631. Increased expression of inducible nitric oxide synthase for human buccal squamous-cell carcinomas: immunohistochemical, reverse transcription-polymerase chain reaction (RT-PCR) and in situ RT-PCR studies. (PubMed id 12369071)9 Chen Y.K....Lin L.M. (2002)
    632. Inducible nitric oxide synthase expression in benign and malignant cutaneous melanocytic lesions. (PubMed id 11400148)9 Massi D....Santucci M. (2001)
    633. Detection of an approximately 100 kD protein with strong immunoreactivity to antibodies specific for inducible nitric oxide synthase (iNOS) but without NOS activity in neutrophils of patients suffering from sepsis: results of a preliminary study. (PubMed id 10669117)9 Richter N....Schimke I. (1999)
    634. Inducible nitric oxide synthase (iNOS) in the human heart: expression and localization in congestive heart failure. (PubMed id 9689595)9 Vejlstrup N.G....Aldershvile J. (1998)
    635. Orazipone inhibits activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 and decreases inducible nitric-oxide synthase expression and nitric oxide production in response to inflammatory stimuli. (PubMed id 18039960)9 Sareila O....Moilanen E. (2008)
    636. [The change of cyclooxygenase-2 and inducible nitric oxide synthase in the gastric mucosa one year after eradication of Helicobacter pylori] (PubMed id 19077474)9 Kim S.S....Chung I.S. (2008)
    637. Localization and expression of inducible nitric oxide synthase in biopsies from patients with interstitial cystitis. (PubMed id 18554637)9 Koskela L.R....Wiklund N.P. (2008)
    638. Budesonide treatment and expression of inducible nitric oxide synthase mRNA in colonic mucosa in collagenous colitis. (PubMed id 16957516)9 Bonderup O.K....Teglbjaerg P.S. (2006)
    639. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer. (PubMed id 16900533)9 Chen C.N....Lee P.H. (2006)
    640. Nitric oxide-mediated mechanism of neuronal nitric oxide synthase and inducible nitric oxide synthase expression during hypoxia in the cerebral cortex of newborn piglets. (PubMed id 16581191)9 Mishra O.P....Delivoria-Papadopoulos M. (2006)
    641. [Expressions of inducible nitric oxide synthase and vascular endothelial growth factor and their relationship with microvessel density in hepatocellular carcinoma.] (PubMed id 15642211)9 Xiao G....Wen J.M. (2005)
    642. Increased nitric oxide levels and iNOS over-expression in oral squamous cell carcinoma. (PubMed id 15743688)9 Connelly S.T....Schmidt B.L. (2005)
    643. Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability. (PubMed id 15528042)9 Won J.S....Singh I. (2004)
    644. Sequential expression of inducible nitric oxide synthase and cyclooxygenase-2 during DMBA-induced hamster buccal pouch carcinogenesis. (PubMed id 15523901)9 Kim S.A....Yoon J.H. (2004)
    645. Structure-activity relationships of 2-aminothiazole derivatives as inducible nitric oxide synthase inhibitor. (PubMed id 15133224)9 Ueda S....Ido M. (2004)
    646. Inducible nitric oxide synthase in the bladder of spinal cord injured patients with a chronic indwelling urinary catheter. (PubMed id 11342896)9 Wall B.M....Cooke C.R. (2001)
    647. Phorbol ester synergistically increases interferon regulatory factor-1 and inducible nitric oxide synthase induction in interferon-gamma-treated RAW 264.7 cells. (PubMed id 11042347)9 Momose I....Tanigawa Y. (2000)
    648. [Forensic pathological significance of iNOS with regard to brain and myocardial damage] (PubMed id 11218753)9 Orihara Y. (2000)
    649. Expression of inducible nitric oxide synthase in colorectal cancer and its association with prognosis. (PubMed id 11145294)9 Ropponen K.M....Kosma V.M. (2000)
    650. Inhibition of inducible nitric oxide synthase in the human intestinal epithelial cell line, DLD-1, by the inducers of heme oxygenase 1, bismuth salts, heme, and nitric oxide donors. (PubMed id 11076874)9 Cavicchi M....Whittle B.J. (2000)
    651. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. (PubMed id 10348815)9 Fu S....Wilson K.T. (1999)
    652. Expression of inducible nitric oxide synthase activity in human colon epithelial cells: modulation by T lymphocyte derived cytokines. (PubMed id 9771406)9 Kolios G....Westwick J. (1998)
    653. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. (PubMed id 9679948)9 Wilson K.T....Meltzer S.J. (1998)
    654. Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS. (PubMed id 9426743)9 Seftel A.D....Haas C. (1997)
    655. Regulation of nitric oxide synthesis in uraemia. (PubMed id 8538931)9 Arese M....Bussolino F. (1995)
    656. L-arginine chlorination results in the formation of a nonselective nitric-oxide synthase inhibitor. (PubMed id 16717106)9 Yang J....Zhang C. (2006)
    657. Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma. (PubMed id 16273602)9 Sun M.H....Jiang Y. (2005)
    658. Monomeric inducible nitric oxide synthase localizes t o peroxisomes in hepatocytes. (PubMed id 16172396)9 Loughran P.A....Billiar T.R. (2005)
    659. Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells. (PubMed id 15718251)9 Chen J....Huang C. (2005)
    660. Stimulation of inducible nitric oxide synthase by monosodium urate crystals in macrophages and expression of iNOS in gouty arthritis. (PubMed id 15566969)9 Chen L....Tsai S.H. (2004)
    661. Acute ethanol exposure modulates expression of inducible nitric-oxide synthase in human astroglia: evidence for a transcriptional mechanism. (PubMed id 15282113)9 Davis R.L. and Syapin P.J. (2004)
    662. Antifibrotic role of inducible nitric oxide synthase. (PubMed id 12009846)9 Ferrini M.G....Gonzalez-Cadavid N.F. (2002)
    663. A specific method for measurement of nitric oxide synthase enzymatic activity in peritoneal biopsies. (PubMed id 10620216)9 Combet S....Devuyst O. (2000)
    664. Therapeutic stimulation of penile nitric oxide synthase (NOS) and related pathways. (PubMed id 12879114)9 Gonzalez-Cadavid N.F. and Rajfer J. (2000)
    665. Regulation of induction of nitric oxide synthase and the inhibitory actions of dexamethasone in the human intestinal epithelial cell line, Caco-2: influence of cell differentiation. (PubMed id 10516652)9 Cavicchi M. and Whittle B.J. (1999)
    666. Induction of inducible nitric oxide synthase is an essential part of tumor necrosis factor-alpha-induced apoptosis in MCF-7 and other epithelial tumor cells. (PubMed id 10616218)9 Binder C....Oellerich M. (1999)
    667. Hemodialysis hypotension: interaction of inhibitors, iNOS, and the interdialytic period. (PubMed id 9892267)9 Kang E.S....Acchiardo S.R. (1999)
    668. The detection and localization of inducible nitric oxide synthase production in the small intestine of patients with coeliac disease. (PubMed id 9744691)9 Beckett C.G....Ciclitira P.J. (1998)
    669. Regulation of the urea cycle enzyme genes in nitric oxide synthesis. (PubMed id 9686345)9 Mori M....Sonoki T. (1998)
    670. Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells. (PubMed id 9754830)9 Darville M.I. and Eizirik D.L. (1998)
    671. Expression of differential nitric oxide synthase isof orms in human normal gastric mucosa and gastric cancer tissue. (PubMed id 9328184)9 Rajnakova A....Moochhala S. (1997)
    672. Nitric oxide synthase content of hypothalamic explants: increase by norepinephrine and inactivated by NO and cGMP. (PubMed id 8633049)9 Canteros G....McCann S.M. (1996)
    673. Nitric oxide synthase in circulating vs. extravasated polymorphonuclear leukocytes. (PubMed id 7595064)9 Miles A.M....Grisham M.B. (1995)
    674. Expression of inducible nitric oxide synthase in cond uits used in patients with diabetes mellitus undergoing coronary revascularizat ion. (PubMed id 19811579)9 Lazar H.L....Chipkin S. (2010)
    675. Exendin-4 inhibits interleukin-1beta-induced iNOS exp ression at the protein level, but not at the transcriptional and posttranscript ional levels, in RINm5F beta-cells. (PubMed id 19398497)9 Kang J.H....Kim M.J. (2009)
    676. Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells. (PubMed id 18976718)9 Baek J.A....Na D.J. (2009)
    677. Overexpression of hepatic inducible nitric oxide synthase in biliary atresia. (PubMed id 18564140)9 Vejchapipat P....Poovorawan Y. (2008)
    678. Prognostic significance of iNOS in epithelial ovarian cancer. (PubMed id 17174383)9 Anttila M.A....Kosma V.M. (2007)
    679. Chemotherapy influences inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) activity on 3D breast cancer cell line. (PubMed id 17120617)9 Oktem G....Omay S.B. (2006)
    680. Pathological consequences of inducible nitric oxide synthase expression in hippocampal slice cultures. (PubMed id 16165295)9 Duport S. and Garthwaite J. (2005)
    681. Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. (PubMed id 16148131)9 Chan G.C....Marsden P.A. (2005)
    682. Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification. (PubMed id 15656623)9 Zhu Y....Silverman R.B. (2005)
    683. Expression of cyclooxygenase-2 and inducible nitric oxide synthase correlates with tumor angiogenesis in endometrial carcinoma. (PubMed id 15750198)9 Li W....Fan B. (2005)
    684. The influence of uropathogenic Escherichia coli and proinflammatory cytokines on the inducible nitric oxide synthase response in human kidney epithelial cells. (PubMed id 15711365)9 Poljakovic M....Persson K. (2005)
    685. Phenotypic modulation of cultured bladder smooth muscle cells and the expression of inducible nitric oxide synthase. (PubMed id 14656765)9 Johansson R. and Persson K. (2004)
    686. Catalase induces the expression of inducible nitric oxide synthase through activation of NF-kappaB and PI3K signaling pathway in Raw 264.7 cells. (PubMed id 15498507)9 Jang B.C....Suh S.I. (2004)
    687. Palmitoylation of inducible nitric-oxide synthase at Cys-3 is required for proper intracellular traffic and nitric oxide synthesis. (PubMed id 15485846)9 Navarro-Lerida I....Rodriguez-Crespo I. (2004)
    688. Expression of beta-catenin, COX-2 and iNOS in colorectal cancer: relevance of COX-2 adn iNOS inhibitors for treatment in Malaysia. (PubMed id 14719508)9 Hong S.K....Seow H.F. (2004)
    689. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in ovarian cancer: correlation with clinical outcome. (PubMed id 14984945)9 Raspollini M.R....Taddei G.L. (2004)
    690. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia. (PubMed id 15191513)9 Kai H....Chayama K. (2004)
    691. Inducible nitric oxide synthase expression is related to angiogenesis, bcl-2 and cell proliferation in hepatocellular carcinoma. (PubMed id 12659238)9 Peng J.P....Zhang S.Z. (2003)
    692. Differential expression of inducible nitric oxide synthase and peroxisome proliferator-activated receptor gamma in non-small cell lung carcinoma. (PubMed id 12763220)9 Lee T.W....Yim A.P. (2003)
    693. Nitric oxide in experimental joint inflammation. Benefit or detriment? (PubMed id 12784039)9 Wahl S.M....Orenstein J.M. (2003)
    694. Suppression of pro-inflammatory cytokine release by selective inhibition of inducible nitric oxide synthase in mucosal explants from patients with ulcerative colitis. (PubMed id 12678336)9 Kankuri E....Moilanen E. (2003)
    695. Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis. (PubMed id 12460898)9 Kisley L.R....Malkinson A.M. (2002)
    696. Double-stranded rna dependence of nitric oxide synthase 2 expression in human bronchial epithelial cell lines BET-1A and BEAS-2B. (PubMed id 11415937)9 Uetani K....Erzurum S.C. (2001)
    697. Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in J774 macrophages exposed to low and to high concentrations of endotoxin. (PubMed id 11171114)9 Korhonen R....Moilanen E. (2001)
    698. Expression of the inducible isoform of nitric oxide synthase in the retinas of human subjects with diabetes mellitus. (PubMed id 11589878)9 Abu El-Asrar A.M....Geboes K. (2001)
    699. Modulation of the inflammatory response in the cardiomyocyte and macrophage. (PubMed id 11680730)9 Bradford Sanders D....Larson D.F. (2001)
    700. Expression of cyclooxygenase-2 and inducible nitric oxide synthase in human ovarian tumors and tumor-associated macrophages. (PubMed id 11585770)9 Klimp A.H....Daemen T. (2001)
    701. Differential expression and regulation of inducible nitric oxide synthase (iNOS) mRNA in human trophoblasts in vitro. (PubMed id 11216878)9 Hambartsoumian E....Seibel M.M. (2001)
    702. Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: possible involvement of COX-2 in the angiogenesis of hepatitis C virus-positive cases. (PubMed id 11350902)9 Rahman M.A....Nagasue N. (2001)
    703. Identification of residues critical for enzymatic activity in the domain encoded by exons 8 and 9 of the human inducible nitric oxide synthase. (PubMed id 11350832)9 Eissa N.T....Moss J. (2001)
    704. Interaction between cyclooxygenase-2 and inducible nitric oxide synthase in gastric cancer. (PubMed id 11606854)9 Son H.J....Rhee J.C. (2001)
    705. Expression of the inducible isoform of nitric oxide synthase in pigment cell lesions of the skin. (PubMed id 10735946)9 Ahmed B. and Van Den Oord J.J. (2000)
    706. Maturation-dependent sequential expression of interferon regulatory factor-1 and inducible nitric oxide synthase in cultured human enterocytes. (PubMed id 11092683)9 Bernstein T....Salzman A.L. (2000)
    707. Detection of inducible nitric oxide synthase (iNOS) mRNA by RT-PCR in ATL patients and HTLV-I infected cell lines: clinical features and apoptosis by NOS inhibitor. (PubMed id 10374875)9 Sonoki T....Mori M. (1999)
    708. Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis. (PubMed id 10589693)9 Datta P.K....Lianos E.A. (1999)
    709. Inducible nitric oxide synthase with transitional cell carcinoma of the bladder. (PubMed id 9915473)9 Swana H.S....Weiss R.M. (1999)
    710. Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. (PubMed id 10073969)9 Baker C.S....Polak J.M. (1999)
    711. [Stable expression of recombinant inducible nitric oxide synthase in NG108-15 cells and its biological characterization] (PubMed id 12548860)9 Zang M.W....Peng X.X. (1999)
    712. Mechanism of inducible nitric oxide synthase inactivation by aminoguanidine and L-N6-(1-iminoethyl)lysine. (PubMed id 9538001)9 Bryk R. and Wolff D.J. (1998)
    713. Expression of inducible nitric oxide synthase (iNOS) mRNA in inflamed esophageal and colonic mucosa in a pediatric population. (PubMed id 9625130)9 Gupta S.K....Garcia J.G. (1998)
    714. Expression of inducible nitric oxide synthase in human burn wounds. (PubMed id 9776857)9 Paulsen S.M....Nanney L.B. (1998)
    715. Inducible nitric oxide synthase and tumor necrosis factor-alpha in myocardium in human dilated cardiomyopathy. (PubMed id 9091515)9 Satoh M....Hiramori K. (1997)
    716. Characterization of inducible nitric-oxide synthase by cytochrome P-450 substrates and inhibitors. Inhibition by chlorzoxazone. (PubMed id 8995391)9 Grant S.K....Kozarich J.W. (1997)
    717. Cloning of rat and human inducible penile nitric oxide synthase. Application for gene therapy of erectile dysfunction. (PubMed id 9096878)9 Garban H....Gonzalez-Cadavid N.F. (1997)
    718. Cytokine-induced nitric oxide synthase gene transcription is blocked by the heat shock response in human liver cells. (PubMed id 8751576)9 de Vera M.E....Geller D.A. (1996)
    719. Proinflammatory agents, IL-8 and IL-10, upregulate inducible nitric oxide synthase expression and nitric oxide production in avian osteoclast-like cells. (PubMed id 8707887)9 Sunyer T....Collin-Osdoby P. (1996)
    720. Nitric oxide synthase in motor neurons after axotomy. (PubMed id 7510317)9 Yu W.H. (1994)
    721. Transcriptional and post-transcriptional regulation o f iNOS expression in human chondrocytes. (PubMed id 19854161)9 Schmidt N....Kleinert H. (2010)
    722. Pitavastatin up-regulates the induction of iNOS through enhanced stabilization of its mRNA in pro-inflammatory cytokine-stimulated hepatocytes. (PubMed id 17936042)9 Habara K....Okumura T. (2008)
    723. Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes. (PubMed id 17543124)9 Skorokhod O.A....Arese P. (2007)
    724. Sarcomas often express constitutive nitric oxide synthases (NOS) but infrequently inducible NOS. (PubMed id 17122636)9 Cunha I.W....Soares F.A. (2006)
    725. [Expression of cyclooxygenase-2 and inducible nitric oxide synthase in tongue hyperplasia and tongue squamous cell carcinoma] (PubMed id 16552960)9 Xu G.X....Pan C.B. (2005)
    726. Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide. (PubMed id 15476266)9 Dijkstra G....Moshage H. (2004)
    727. Inducible nitric oxide synthase (iNOS) is expressed similarly in multiple aberrant crypt foci and colorectal tumors from the same patients. (PubMed id 11212223)9 Hao X.P....Pretlow T.P. (2001)
    728. Quercetin tetraacetyl derivative inhibits LPS-induced nitric oxide synthase (iNOS) expression in J774A.1 cells. (PubMed id 20417174)9 Ortega M.G....Chiabrando G.A. (2010)
    729. Expression of pro-inflammatory protein, iNOS, VEGF an d COX-2 in oral squamous cell carcinoma (OSCC), relationship with angiogenesis and their clinico-pathological correlation. (PubMed id 19300368)9 Sappayatosok K....Chaisri U. (2009)
    730. Inducible nitric oxide synthase expression in melanoma: implications in lymphangiogenesis. (PubMed id 18660796)9 Massi D....Miracco C. (2009)
    731. The effects of PDTC on interleukin-1beta-induced nitr ic oxide production in chondrocytes. (PubMed id 19513610)9 Liu J....Li X. (2009)
    732. Increased mucosal nitric oxide production in ulcerati ve colitis is mediated in part by the enteroglial-derived S100B protein. (PubMed id 19558426)9 Cirillo C....Cuomo R. (2009)
    733. Beta-carotene inhibits Helicobacter pylori-induced ex pression of inducible nitric oxide synthase and cyclooxygenase-2 in human gastr ic epithelial AGS cells. (PubMed id 20388956)9 Jang S.H....Kim H. (2009)
    734. Chitosomes loaded with cranberry proanthocyanidins at tenuate the bacterial lipopolysaccharide-induced expression of iNOS and COX-2 i n raw 264.7 macrophages. (PubMed id 19694605)9 Madrigal-Carballo S....Molina F. (2009)
    735. Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation. (PubMed id 18567803)9 Lee H.C....Hong S.I. (2008)
    736. Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. (PubMed id 18022235)9 Ashino T....Yoshida T. (2008)
    737. Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. (PubMed id 18481332)9 Pae H.O....Chung H.T. (2008)
    738. Sympathetic neurotransmission modulates expression of inflammatory markers in the rat retina. (PubMed id 17067575)9 Steinle J.J. (2007)
    739. The cardioprotective effects of thoracal epidural anestesia are induced by the expression of vascular endothelial growth factor and inducible nitric oxide synthase in cardiopulmonary bypass surgery. (PubMed id 17308528)9 Gonca S....Bayindir O. (2007)
    740. [Expressions of and the effect of smoking on vascular endothelial growth factor and induced nitric oxide synthase in lung tissues of chronic obstructive pulmonary disease patients] (PubMed id 17988548)9 Huo J.M....Shi Y.Z. (2007)
    741. L-arginine prevents reduced expression of endothelial nitric oxide synthase (NOS) in pulmonary arterioles of broilers exposed to cool temperatures. (PubMed id 16169754)9 Tan X....Wang X.L. (2007)
    742. [Ovarian steroid cell tumor, not otherwise specified: a clinicopathologic study] (PubMed id 17980097)9 Ye L....Yang K.X. (2007)
    743. Inducible nitric oxide synthase activity does not contribute to the maintenance of peripheral vascular tone in patients with heart failure. (PubMed id 16803456)9 Dover A.R....Newby D.E. (2006)
    744. Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection. (PubMed id 16713109)9 Ruano D....CastaA+o A. (2006)
    745. Cyclooxygenase-2 and inducible nitric oxide synthase expression in thyroid neoplasms and their clinicopathological correlation. (PubMed id 17179688)9 Kim K.H....Kim J.M. (2006)
    746. [Inhibitory effect of cholecystokinin octapeptide on lipopolysaccharide-elicited inducible nitric oxide synthase expression in vascular endothelial cells] (PubMed id 16512640)9 Yan J....Ling Y.L. (2006)
    747. Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms. (PubMed id 16765486)9 Pannu R. and Singh I. (2006)
    748. Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production. (PubMed id 15740980)9 Srisook K. and Cha Y.N. (2005)
    749. Differential effects of anesthetics on endotoxin-induced liver injury. (PubMed id 15824646)9 Suliburk J.W....Mercer D.W. (2005)
    750. Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia. (PubMed id 15683737)9 Jang B.C....Suh S.I. (2005)
    751. Agonist-dependent variablity of contributions of nitric oxide and prostaglandins in human skeletal muscle. (PubMed id 15563630)9 Schrage W.G....Joyner M.J. (2005)
    752. Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated raw 264.7 cells: the role of heme oxygenase-1 and endogenous nitric oxide. (PubMed id 15220209)9 Sumi D. and Ignarro L.J. (2004)
    753. Biochemical aspects of nitric oxide. (PubMed id 15134561)9 Mariotto S....Suzuki H. (2004)
    754. [The expression of VEGF and iNOS in laryngeal squamous cell carcinoma and its clinical significance] (PubMed id 15831042)9 Sun N. and Ge R. (2004)
    755. Gene expression of nitric oxide synthase by human umbilical vein endothelial cells: the effect of fetal plasma from pregnancy with umbilical placental vascular disease. (PubMed id 12504936)9 Wang X....Trudinger B. (2003)
    756. Effect of montelukast pretreatment on inducible nitric oxide synthase mRNA expression in the lungs of antigen-challenged allergic mice. (PubMed id 14656364)9 Sade K....Kivity S. (2003)
    757. Functional inhibition of constitutive nitric oxide synthase in a rat model of sepsis. (PubMed id 12016107)9 Scott J.A....McCormack D.G. (2002)
    758. Altered arterial expression patterns of inducible and endothelial nitric oxide synthase in pulmonary plexogenic arteriopathy caused by congenital heart disease. (PubMed id 11371423)9 Berger R.M....Mooi W.J. (2001)
    759. Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage. (PubMed id 11597171)9 Vuolteenaho K....Moilanen E. (2001)
    760. Are myoepithelial cells responsible for the widespread expression of inducible nitric oxide synthase in pleomorphic adenoma? An immunohistochemical study. (PubMed id 10890559)9 Brennan P.A....Downie I.P. (2000)
    761. Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. (PubMed id 11156233)9 Ekmekcioglu S....Grimm E.A. (2000)
    762. Mutations at lysine 525 of inducible nitric-oxide synthase affect its Ca2+-independent activity. (PubMed id 10978319)9 Lee S.J....Stull J.T. (2000)
    763. Expression of the inducible NO synthase in human monocytic U937 cells allows high output nitric oxide production. (PubMed id 9886246)9 Bertholet S....MauAl J. (1999)
    764. Immunohistochemical localization of inducible nitric oxide synthase on human fetal amnion in intra-amniotic infection. (PubMed id 9822514)9 Hsu C.D....Parkash V. (1998)
    765. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. (PubMed id 9464988)9 Bhat N.R....Hogan E.L. (1998)
    766. Transfection of inducible nitric oxide synthase gene causes apoptosis in vascular smooth muscle cells. (PubMed id 9743513)9 Iwashina M....Hirata Y. (1998)
    767. Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice. (PubMed id 9671763)9 Ambs S....Harris C.C. (1998)
    768. Up-regulation of inducible nitric oxide synthase and production of nitric oxide by the Swarm rat and human chondrosarcoma. (PubMed id 9877390)9 Di Cesare P.E....Amin A.R. (1998)
    769. Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase messenger RNA expression in the rat in vivo. (PubMed id 9118670)9 Liu S.F....Evans T.W. (1997)
    770. Relationships between NADPH diaphorase staining and neuronal, endothelial, and inducible nitric oxide synthase and cytochrome P450 reductase immunoreactivities in guinea-pig tissues. (PubMed id 9049638)9 Young H.M....Tracey W.R. (1997)
    771. Tyrosine kinases are involved with the expression of inducible nitric oxide synthase in human articular chondrocytes. (PubMed id 7539812)9 Geng Y....Lotz M. (1995)
    772. Expression of cyclooxygenase-2 and its relation to hi stological grade, inducible nitric oxide synthase, matrix metalloproteinase-2, CD-34, Caspase-3, and CD8 in invasive ductal carcinoma of the breast. (PubMed id 20174726)9 Atik E....Aban N. (2010)
    773. Cerebral and peripheral changes occurring in nitric o xide (NO) synthesis in a rat model of sleeping sickness: identification of brai n iNOS expressing cells. (PubMed id 20169057)9 Amrouni D....Cespuglio R. (2010)
    774. COX-2 and iNOS are critical in advanced glycation end product-activated chondrocytes in vitro. (PubMed id 19371268)9 Huang C.Y....Ho L.J. (2009)
    775. The impact of intracellular generation of nitric oxid e on the radiation response of human tumor cells. (PubMed id 19580492)9 Singh S....Stratford I.J. (2009)
    776. The anti-inflammatory role of heme oxygenase-1 in lip opolysaccharide and cytokine-stimulated inducible nitric oxide synthase and nit ric oxide production in human periodontal ligament cells. (PubMed id 19961388)9 Kim Y.S....Kim E.C. (2009)
    777. Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells. (PubMed id 19198806)9 Zhang X....Zhong L. (2009)
    778. [Relationship of nitric oxide and nitric oxide synthase with varicocele infertility] (PubMed id 18572859)9 Xu Y....Peng Y.F. (2008)
    779. Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. (PubMed id 17913526)9 HAomAolAoinen M....Moilanen E. (2008)
    780. Aspirin and clopidogrel treatment impair nitric oxide biosynthesis by platelets. (PubMed id 18606420)9 O'Kane P.D....Ferro A. (2008)
    781. Estradiol 17-beta and progesterone modulate inducible nitric oxide synthase and high mobility group box 1 expression in human endometrium. (PubMed id 18483013)9 Zicari A....Ticconi C. (2008)
    782. Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt. (PubMed id 18205920)9 Xing B....Bing G. (2008)
    783. Suppression of inducible nitric oxide synthase expression and nitric oxide production by macrolide antibiotics in sulfur mustard-exposed airway epithelial cells. (PubMed id 18684233)9 Gao X....Ray P. (2008)
    784. Effects of astaxanthin on the production of NO and the expression of COX-2 and iNOS in LPS-stimulated BV2 microglial cells. (PubMed id 19131704)9 Choi S.K....Chang H.I. (2008)
    785. Induction of inducible nitric oxide synthase and apoptosis by LPS and TNF-alpha in nasal microvascular endothelial cells. (PubMed id 17851925)9 Arai S....Yamashita T. (2008)
    786. Distinct inflammatory properties of late-activated macrophages in inflammatory myopathies. (PubMed id 19364061)9 Rostasy K.M....Schulz-Schaeffer J. (2008)
    787. Gene therapy via inducible nitric oxide synthase: a tool for the treatment of a diverse range of pathological conditions. (PubMed id 18644193)9 McCarthy H.O....Hirst D.G. (2008)
    788. Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade. (PubMed id 17031850)9 Vaillancourt F....Benderdour M. (2007)
    789. [Study on the inhibition of vascular endothelial grow th factor expression in Tca8113 cell by inducible nitric oxide synthase gene RN A interference] (PubMed id 17462148)9 Zeng S.G....Zhang J.R. (2007)
    790. Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I. (PubMed id 17291856)9 Bergeron C....Hamid Q. (2007)
    791. Heme oxygenase-1 induction by (S)-enantiomer of YS-51 (YS-51S), a synthetic isoquinoline alkaloid, inhibits nitric oxide production and nuclear factor-kappaB translocation in ROS 17/2.8 cells activated with inflammatory stimulants. (PubMed id 17920533)9 Chaea H.J....Chang K.C. (2007)
    792. Inflammatory cytokines promote inducible nitric oxide synthase-mediated DNA damage in hamster gallbladder epithelial cells. (PubMed id 18081227)9 Kitasato A....Kanematsu T. (2007)
    793. Inhibition of inducible nitric-oxide synthase expression by (5R)-5-hydroxytriptolide in interferon-gamma- and bacterial lipopolysaccharide-stimulated macrophages. (PubMed id 16166270)9 Zhou R....Zuo J.P. (2006)
    794. Ciprofloxacin inhibits cytokine-induced nitric oxide production in human colonic epithelium. (PubMed id 16968468)9 Kolios G....Kouroumalis E. (2006)
    795. Quiescent interplay between inducible nitric oxide synthase and tumor necrosis factor-alpha: influence on transplant graft vasculopathy in renal allograft dysfunction. (PubMed id 16827641)9 Elahi M.M....Hakim N.S. (2006)
    796. Pulmonary hypertension triggered by lipopolysaccharide in ascites-susceptible and -resistant broilers is not amplified by aminoguanidine, a specific inhibitor of inducible nitric oxide synthase. (PubMed id 16553285)9 Bowen O.T....Wideman R.F. (2006)
    797. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. (PubMed id 16609073)9 Deng W.G....Wu K.K. (2006)
    798. The effects of the inhibition of inducible nitric oxide synthase on angiogenesis of epithelial ovarian cancer. (PubMed id 16580304)9 Malone J.M....Munkarah A.R. (2006)
    799. Comparative effects of azelnidipine and other Ca2+-channel blockers on the induction of inducible nitric oxide synthase in vascular smooth muscle cells. (PubMed id 16495772)9 Ma J....Nakajima T. (2006)
    800. Increased protein expression of both inducible nitric oxide synthase and cyclooxygenase-2 in human colon cancers. (PubMed id 16216410)9 Ohta T....Ochiai A. (2006)
    801. Opioid-induced hyperalgesia in a murine model of postoperative pain: role of nitric oxide generated from the inducible nitric oxide synthase. (PubMed id 16508403)9 CAclAcrier E....Puig M.M. (2006)
    802. Endotoxin-induced acute renal failure in rats: effects of L-arginine and nitric oxide synthase inhibition on renal function. (PubMed id 16245240)9 Schramm L....Wanner C. (2005)
    803. Chloroquine induces the expression of inducible nitric oxide synthase in C6 glioma cells. (PubMed id 15683746)9 Chen T.H....Lee H.M. (2005)
    804. [Expression of inductive nitric oxide synthase and vascular endothelial growth factor in colonic carcinoma, and their effects on tumor angiogenesis] (PubMed id 16299654)9 Yin P....Liu Z.C. (2005)
    805. Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease. (PubMed id 16041799)9 Okuno T....Sakoda S. (2005)
    806. Ischemic damage increases nitric oxide production via inducible nitric oxide synthase in the cochlea. (PubMed id 16154689)9 Morizane I....Gyo K. (2005)
    807. [Nitric oxide and nitric oxide synthase in patients with chronic hepatitis B] (PubMed id 16027781)9 Wang K....Wang H.M. (2005)
    808. Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy. (PubMed id 16099602)9 Chen H.H....Lee W.Y. (2005)
    809. The effects of nitric oxide in acute lung injury. (PubMed id 16256443)9 Mehta S. (2005)
    810. Effects of C-peptide on expression of eNOS and iNOS in human cavernosal smooth muscle cells. (PubMed id 15351621)9 Li H....Sima A.A. (2004)
    811. [Expression of nitric oxide synthase and its significance in nasal polyps] (PubMed id 15362679)9 Sun J....Liu R. (2004)
    812. Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia. (PubMed id 15104249)9 Chen C.J....Chen S.Y. (2004)
    813. Biphasic induction of heme oxygenase-1 expression in macrophages stimulated with lipopolysaccharide. (PubMed id 15450936)9 Srisook K. and Cha Y.N. (2004)
    814. Inducible nitric oxide synthase and vascular endothelial growth factor are colocalized in the retinas of human subjects with diabetes. (PubMed id 15004583)9 Abu El-Asrar A.M....Geboes K. (2004)
    815. [Expression of neuronal nitric oxide synthase and inducible nitric oxide synthase in the erector spinal muscles in idiopathic scoliosis] (PubMed id 15379275)9 Zhao Y. and Qiu G.X. (2004)
    816. 20(S)-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-kappaB in RAW 264.7 macrophages stimulated with lipopolysaccharide. (PubMed id 15036657)9 Oh G.S....Chung H.T. (2004)
    817. Evidences for iNOS expression and nitric oxide produc tion in the human macrophages. (PubMed id 12871028)9 Panaro M.A....Mitolo V. (2003)
    818. Role of nitric oxide in D-galactosamine-induced cell death and its protection by PGE1 in cultured hepatocytes. (PubMed id 12620377)9 Siendones E....MuntanAc J. (2003)
    819. The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines. (PubMed id 14566822)9 Park S.W....Sung M.W. (2003)
    820. Localization of inducible nitric oxide synthase and endothelial constitutive nitric oxide synthase in airway mucosa of toluene diisocyanate-induced asthma. (PubMed id 12974195)9 Lee S.K....Park C.S. (2003)
    821. Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells. (PubMed id 14599552)9 Shen L.J....Shen W.C. (2003)
    822. Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone. (PubMed id 12594587)9 Tabernero A....Andriantsitohaina R. (2003)
    823. Role of protein kinase C in BSA-AGE-mediated inducible nitric oxide synthase expression in RAW 264.7 macrophages. (PubMed id 12826263)9 Wu C.H....Lee H.M. (2003)
    824. Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2. (PubMed id 11910358)9 Resta-Lenert S. and Barrett K.E. (2002)
    825. Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway. (PubMed id 12379662)9 Cieslik K....Wu K.K. (2002)
    826. The role of inducible nitric oxide synthase in aseptic loosening after total hip arthroplasty. (PubMed id 12188499)9 Suh K.T....Jung J.S. (2002)
    827. Comparison of tumor necrosis factor-alpha effect on the expression of iNOS in macrophage and cardiac myocytes. (PubMed id 11192310)9 Sanders D.B....Yang B. (2001)
    828. Nitric oxide from the inducible nitric oxide synthase (iNOS) increases the expression of cytochrome P450 2E1 in iNOS-null hepatocytes in the absence of inflammatory stimuli. (PubMed id 11396931)9 Zamora R....Billiar T.R. (2001)
    829. The expression of cyclooxygenase 2 and inducible nitric oxide synthase indicates no active inflammation in vulvar vestibulitis. (PubMed id 11437722)9 Bohm-Starke N....Hilliges M. (2001)
    830. Inhibitory effects of 17beta-estradiol and progesterone on ovarian carcinoma cell proliferation: a potential role for inducible nitric oxide synthase. (PubMed id 11426974)9 Keith Bechtel M. and Bonavida B. (2001)
    831. Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology. (PubMed id 11532247)9 LA1th H.J....Arendt T. (2001)
    832. Nitric oxide and nitric oxide synthase in Huntington's disease. (PubMed id 11288139)9 Deckel A.W. (2001)
    833. Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. (PubMed id 11331078)9 Chen Y.C....Yang L.L. (2001)
    834. Inducible nitric oxide synthase expression before and after eradication of Helicobacter pylori in different forms of gastritis. (PubMed id 11267845)9 Antos D....Hatz R.A. (2001)
    835. Current roles of nitric oxide in gastrointestinal disorders. (PubMed id 11595446)9 Cho C.H. (2001)
    836. Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. (PubMed id 11312402)9 Redington A.E....Polak J.M. (2001)
    837. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. (PubMed id 11506818)9 Surh Y.J....Lee S.S. (2001)
    838. Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation. (PubMed id 10751555)9 Chen Y....Lee T.J. (2000)
    839. Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mechanism. (PubMed id 10713108)9 Akama K.T. and Van Eldik L.J. (2000)
    840. Time course of nitric oxide synthase generation after gluten exposure in the rectal mucosa of gluten-sensitive patients. (PubMed id 11145285)9 Niveloni S....Goldin E. (2000)
    841. Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. (PubMed id 11156228)9 Marrogi A.J....Harris C.C. (2000)
    842. Clinical course of cardiomyopathy in HIV-infected patients with or without encephalopathy related to the myocardial expression of tumour necrosis factor-alpha and nitric oxide synthase. (PubMed id 10839591)9 Barbaro G....Barbarini G. (2000)
    843. Physical exercise-induced expression of inducible nitric oxide synthase and heme oxygenase-1 in human leukocytes: effects of RRR-alpha-tocopherol supplementation. (PubMed id 11232592)9 Niess A.M....Fehrenbach E. (2000)
    844. [Nitric oxide synthase and vascular endothelial growth factor expression in hepatocellular carcinoma and their relation to angiogenesis] (PubMed id 11778555)9 Wang L....Sun H. (2000)
    845. Tumor necrosis factor-alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma cells. (PubMed id 11095498)9 Macdonald N.J. and Taglialatela G. (2000)
    846. Radicicol suppresses expression of inducible nitric-oxide synthase by blocking p38 kinase and nuclear factor-kappaB/Rel in lipopolysaccharide-stimulated macrophages. (PubMed id 10900231)9 Jeon Y.J....Kim H.M. (2000)
    847. Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes. (PubMed id 9931117)9 LaPointe M.C. and IsenoviA8 E. (1999)
    848. Inducible nitric oxide synthase and nitric oxide production in Leishmania infantum-infected human macrophages stimulated with interferon-gamma and bacterial lipopolysaccharide. (PubMed id 10592110)9 Panaro M.A....Brandonisio O. (1999)
    849. Nitric oxide levels in exhaled air and inducible nitric oxide synthase immunolocalization in pulmonary sarcoidosis. (PubMed id 10573228)9 Moodley Y.P....Lalloo U.G. (1999)
    850. Lipid hydroperoxides inhibit nitric oxide production in RAW264.7 macrophages. (PubMed id 10218641)9 Huang A....Stone W.L. (1999)
    851. Intensity of myocardial expression of inducible nitric oxide synthase influences the clinical course of human immunodeficiency virus-associated cardiomyopathy. Gruppo Italiano per lo Studio Cardiologico dei pazienti affetti da AIDS (GISCA). (PubMed id 10468523)9 Barbaro G....Barbarini G. (1999)
    852. Inhibitory effect of Ginkgo biloba extract on the expression of inducible nitric oxide synthase in endothelial cells. (PubMed id 10535759)9 Cheung F....O K. (1999)
    853. Neutrophil accumulation and damage to the gastric mucosa in resuscitated hemorrhagic shock is independent of inducible nitric oxide synthase. (PubMed id 10353536)9 Tsukada K....Billiar T.R. (1999)
    854. Human dermal microvascular endothelial cells express inducible nitric oxide synthase in vitro. (PubMed id 10084320)9 Hoffmann G....Sepp N. (1999)
    855. Role of the cyclic AMP-protein kinase A pathway in lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages. Involvement of cyclooxygenase-2. (PubMed id 10531359)9 Chen C.C....Chen W.C. (1999)
    856. Expression of endothelial and inducible nitric oxide synthase in human glomerulonephritis. (PubMed id 9607210)9 Furusu A....Kohno S. (1998)
    857. Inhibition on inducible nitric oxide synthase. (PubMed id 19649818)9 Rimoldi J.M. and Chimote S.S. (1998)
    858. Phospholipase A2 metabolites regulate inducible nitric oxide synthase in myocytes. (PubMed id 9453306)9 LaPointe M.C. and Sitkins J.R. (1998)
    859. Nitric oxide synthase activity in human renal cell carcinoma. (PubMed id 9679928)9 Jansson O.T....Wiklund N.P. (1998)
    860. Cloning and characterization of human inducible nitri c oxide synthase splice variants: a domain, encoded by exons 8 and 9, is critic al for dimerization. (PubMed id 9636200)9 Eissa N.T....Moss J. (1998)
    861. Increased level of exhaled nitric oxide and up-regulation of inducible nitric oxide synthase in patients with primary lung cancer. (PubMed id 9716040)9 Liu C.Y....Kuo H.P. (1998)
    862. Expression of inducible nitric oxide synthase and formation of peroxynitrite in posttransplant obliterative bronchiolitis. (PubMed id 9703237)9 Mason N.A....Polak J.M. (1998)
    863. Expression of nitric oxide synthase isoforms in normal human tracheobronchial epithelial cells in vitro: dependence on retinoic acid and the state of differentiation. (PubMed id 9635256)9 Norford D....Nettesheim P. (1998)
    864. Bacterial infection induces nitric oxide synthase in human neutrophils. (PubMed id 9011564)9 Wheeler M.A....Sessa W.C. (1997)
    865. Immunolocalization of nitric oxide synthases at the postsynaptic domain of human and rat neuromuscular junctions--light and electron microscopic studies. (PubMed id 9398448)9 Yang C.C....Askanas V. (1997)
    866. Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis. (PubMed id 9252518)9 Rockey D.C. and Chung J.J. (1997)
    867. Bryostatin-1 and IFN-gamma synergize for the expression of the inducible nitric oxide synthase gene and for nitric oxide production in murine macrophages. (PubMed id 9192827)9 Taylor L.S....Espinoza-Delgado I. (1997)
    868. Ca2+ or phorbol ester but not inflammatory stimuli elevate inducible nitric oxide synthase messenger ribonucleic acid and nitric oxide (NO) release in avian osteoclasts: autocrine NO mediates Ca2+-inhibited bone resorption. (PubMed id 9112415)9 Sunyer T....Collin-Osdoby P. (1997)
    869. (-)-Epigallocatechin-3-gallate blocks the induction o f nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. (PubMed id 9281609)9 Lin Y.L. and Lin J.K. (1997)
    870. [Study of nitric oxide synthases, nitric oxide and tumor necrosis factor in different types of ascites] (PubMed id 9592341)9 Lu F....Huo J. (1996)
    871. The role of nitric oxide in ethanol-induced gastrointestinal dysfunction. (PubMed id 8986213)9 Keshavarzian A....Fields J.Z. (1996)
    872. Structural diversity in the 5'-untranslated region of cytokine-stimulated human inducible nitric oxide synthase mRNA. (PubMed id 7537735)9 Chu S.C....Moss J. (1995)
    873. Effect of asymmetric dimethyl arginine on nitric oxid e synthase activity in normal and pre-eclamptic placentae. (PubMed id 8743168)9 King R.G....Brennecke S.P. (1995)
    874. Nitric oxide limits transcriptional induction of nitr ic oxide synthase in CNS glial cells. (PubMed id 7516158)9 Park S.K....Murphy S. (1994)
    875. Inducible nitric-oxide-synthase mRNA is transiently expressed and destroyed by a cycloheximide-sensitive process. (PubMed id 7508391)9 Evans T....Cohen J. (1994)
    876. Extremely low frequency electromagnetic fields modula te expression of inducible nitric oxide synthase, endothelial nitric oxide synt hase and cyclooxygenase-2 in the human keratinocyte cell line HaCat: potential therapeutic effects in wound healing. (PubMed id 19799606)9 Patruno A....Reale M. (2010)
    877. Inhibition of iNOS and COX-2 in human whole blood ex vivo and monocyte-macrophage J774 cells by a new group of aminothiopyrimidone derivatives. (PubMed id 19200742)9 Cardile V....Santagati A. (2009)
    878. Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases. (PubMed id 19285099)9 Huang T.Y....Liao C.L. (2009)
    879. Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia. (PubMed id 19776611)9 Nishizawa H....Udagawa Y. (2009)
    880. Expression of inducible nitric oxide synthase and vascular endothelial growth factor in ameloblastoma. (PubMed id 19165019)9 Chen W.L....Wang J.G. (2009)
    881. Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model. (PubMed id 18502427)9 Xiong W....Johanning J. (2009)
    882. Cellular ADMA: Regulation and action. (PubMed id 19682580)9 Teerlink T....Wilcox C.S. (2009)
    883. Influence of progesterone on endometrial nitric oxide synthase expression. (PubMed id 18710710)9 Khorram O. and Han G. (2009)
    884. iNOS activity is necessary for the cytotoxic and immu nogenic effects of doxorubicin in human colon cancer cells. (PubMed id 19925669)9 De Boo S....Riganti C. (2009)
    885. Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages. (PubMed id 18325727)9 Kim K.M....Chung H.T. (2008)
    886. The effect of pioglitazone on nitric oxide synthase in patients with type 2 diabetes mellitus. (PubMed id 19040587)9 Nishio K....Kobayashi Y. (2008)
    887. TGF beta 1 and TNF alpha potentiate nitric oxide production in astrocyte cultures by recruiting distinct subpopulations of cells to express NOS-2. (PubMed id 18035449)9 Hamby M.E....Hewett J.A. (2008)
    888. The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. (PubMed id 17997414)9 Xie X.Q....Hojo N. (2008)
    889. Effect of sildenafil citrate on interleukin-1beta-induced nitric oxide synthesis and iNOS expression in SW982 cells. (PubMed id 18587266)9 Kim K.O....Han J.S. (2008)
    890. Inducible nitric oxide synthase expressions in different lung injury models and the protective effect of aminoguanidine. (PubMed id 18790185)9 Yeh D.Y....Wang D. (2008)
    891. Smooth muscle cells, dendritic cells and mast cells are sources of TNFalpha and nitric oxide in human carotid artery atherosclerosis. (PubMed id 18561985)9 Bacci S....Romagnoli P. (2008)
    892. Topical application of a bioadhesive black raspberry gel modulates gene expression and reduces cyclooxygenase 2 protein in human premalignant oral lesions. (PubMed id 18559542)9 Mallery S.R....Stoner G.D. (2008)
    893. Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. (PubMed id 18644994)9 Chittezhath M....Agarwal R. (2008)
    894. Inducible nitric oxide synthase (iNOS): role in asthma pathogenesis. (PubMed id 18341205)9 Batra J....Ghosh B. (2007)
    895. Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling. (PubMed id 17513437)9 Mori M. (2007)
    896. The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells. (PubMed id 17184768)9 GarcA-a-Mediavilla V....GonzA!lez-Gallego J. (2007)
    897. Inducible nitric oxide synthase mediates hypoxia-induced hypoxia-inducible factor-1 alpha activation and vascular endothelial growth factor expression in oxygen-induced retinopathy. (PubMed id 18087198)9 He T....Xing Y.Q. (2007)
    898. Expression of HIF-1alpha and iNOS in astrocytic gliomas: a clinicopathological study. (PubMed id 16724682)9 Giannopoulou E....Kardamakis D. (2006)
    899. IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathways. (PubMed id 16881054)9 Kim Y.J....Han I.O. (2006)
    900. Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation. (PubMed id 16520738)9 Won J.H....Lee K.T. (2006)
    901. Up-regulation of hypoxia inducible factor 1alpha by isoflurane in Hep3B cells. (PubMed id 17122584)9 Li Q.F....Su D.S. (2006)
    902. Mitochondrial arginase II modulates nitric-oxide synthesis through nonfreely exchangeable L-arginine pools in human endothelial cells. (PubMed id 16801455)9 Topal G....David-Dufilho M. (2006)
    903. Nitric oxide synthases are associated with bronchial dysplasia. (PubMed id 16420964)9 Puhakka A.R....Kinnula V.L. (2006)
    904. Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation. (PubMed id 16000635)9 Martin L.J....Liu Z. (2005)
    905. Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo. (PubMed id 15647265)9 Connelly L....Hobbs A.J. (2005)
    906. Hypoxia-induced expression of HIF-1alpha and its target genes in umbilical venous endothelial cells of Tibetans and immigrant Han. (PubMed id 15970466)9 Gao W....Shi J. (2005)
    907. Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones. (PubMed id 16326428)9 Shin S.G....Choi W.S. (2005)
    908. Expression of inducible nitric oxide synthase and effects of L-arginine on colonic nitric oxide production and fluid transport in patients with 'minimal colitis'. (PubMed id 16165717)9 Perner A....Rask-Madsen J. (2005)
    909. A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice. (PubMed id 15855318)9 Fujimoto M....Kaneki M. (2005)
    910. LY294002 inhibits LPS-induced NO production through a inhibition of NF-kappaB activation: independent mechanism of phosphatidylinositol 3-kinase. (PubMed id 15894110)9 Kim Y.H....Kwon T.K. (2005)
    911. Inflammatory cell expression of cyclooxygenase-2 in the multiple sclerosis lesion. (PubMed id 15020063)9 Rose J.W....Carlson N.G. (2004)
    912. Expression of endothelial and inducible nitric oxide synthases is modulated in the endometrium of cyclic and early pregnant mares. (PubMed id 15740692)9 Welter H....Einspanier R. (2004)
    913. Inflammatory mediators in autoimmune lacrimal gland disease in MRL/Mpj mice. (PubMed id 15223808)9 Jabs D.A....Whittum-Hudson J.A. (2004)
    914. Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFN-gamma-inducible 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis. (PubMed id 14977928)9 Raju B....Weiden M.D. (2004)
    915. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic cancer. (PubMed id 15165031)9 Franco L....Bassi C. (2004)
    916. Vascular endothelium is the organ chiefly responsible for the catabolism of plasma asymmetric dimethylarginine--an explanation for the elevation of plasma ADMA in disorders characterized by endothelial dysfunction. (PubMed id 15325021)9 McCarty M.F. (2004)
    917. Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance. (PubMed id 15088099)9 Hara A. and Okayasu I. (2004)
    918. High microvascular density is correlated with high VEGF, iNOS and COX-2 expression in penetrating growth-type early gastric carcinomas. (PubMed id 15569052)9 Ichinoe M....Okayasu I. (2004)
    919. Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis. (PubMed id 15023380)9 Dumond H....Jouzeau J.Y. (2004)
    920. Gingival endothelial and inducible nitric oxide synthase levels during orthodontic treatment: a cross-sectional study. (PubMed id 15673150)9 D'Attillio M....Perinetti G. (2004)
    921. Protective effect of pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, on ischemia-induced neuronal damage. (PubMed id 15327760)9 Kurosaki R....Araki T. (2004)
    922. Endothelial nitric oxide synthase (NOS) is upregulated in rapid progressive pulmonary hypertension of the newborn. (PubMed id 12904860)9 Hoehn T....Wadsworth R.M. (2003)
    923. [Expression and significance of nitric oxide synthase mRNAs and proteins in giant cell tumors of bone] (PubMed id 14613648)9 Li H.G....Dong S.K. (2003)
    924. High expression of nitric oxide synthases is a favorable prognostic sign in non-small cell lung carcinoma. (PubMed id 14678024)9 Puhakka A....Soini Y. (2003)
    925. Estrogen increases inducible nitric oxide synthase gene expression. (PubMed id 12748480)9 Walsh L.S....Mershon J.L. (2003)
    926. Expression of nitric oxide synthases in keratinocytes after UVB irradiation. (PubMed id 14615895)9 Chang H.R....Yu H.S. (2003)
    927. Up-regulation of inducible nitric oxide synthase in Helicobacter pylori-associated gastritis may represent an increased risk factor to develop gastric carcinoma of the intestinal type. (PubMed id 14760971)9 Rieder G....Enders G.A. (2003)
    928. Sildenafil induces delayed preconditioning through in ducible nitric oxide synthase-dependent pathway in mouse heart. (PubMed id 12637371)9 Salloum F....Kukreja R.C. (2003)
    929. [Influence of beta-endorphin on function of immune system of patients with cerebral hemorrhage] (PubMed id 14521744)9 Jin X....Gao Y. (2003)
    930. IL-4 and interferon gamma regulate expression of inducible nitric oxide synthase in chronic lymphocytic leukemia cells. (PubMed id 12592345)9 Levesque M.C....Weinberg J.B. (2003)
    931. [Enhancement by FK506 of triptolide-induced inhibition of expression of COX-2 and iNOS in human rheumatoid arthritis synovial fibroblasts] (PubMed id 12621554)9 (2003)
    932. Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation. (PubMed id 12507903)9 Bruch-Gerharz D....Kolb-Bachofen V. (2003)
    933. Involvement of oxidative and nitrosative stress in promoting retinal vasculitis in patients with Eales' disease. (PubMed id 12849870)9 Rajesh M....Ramakrishnan S. (2003)
    934. Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme. (PubMed id 11838804)9 Cuny E....Demotes-Mainard J. (2002)
    935. N-Aryl N'-hydroxyguanidines, a new class of NO-donors after selective oxidation by nitric oxide synthases: structure-activity relationship. (PubMed id 11831907)9 Renodon-CorniA"re A....Mansuy D. (2002)
    936. Up-regulation of cyclooxygenase-2 expression in lymphocytic thyroiditis and thyroid tumors: significant correlation with inducible nitric oxide synthase. (PubMed id 11939728)9 Nose F....Okayasu I. (2002)
    937. Estrogen increases iNOS expression in the ovine coronary artery. (PubMed id 12181148)9 Mershon J.L....Clark K.E. (2002)
    938. Expression of type 2 nitric oxide synthase and vascular endothelial growth factor in oral dysplasia. (PubMed id 12465010)9 Brennan P.A....Mellor T.K. (2002)
    939. Suppression of promoter-dependent transcriptional activity of inducible nitric oxide synthase by sodium butyrate in colon cancer cells. (PubMed id 11825662)9 Sasahara Y....Wakabayashi K. (2002)
    940. Peroxynitrite increases iNOS through NF-kappaB and decreases prostacyclin synthase in endothelial cells. (PubMed id 11788351)9 Cooke C.L. and Davidge S.T. (2002)
    941. [The arginine paradox] (PubMed id 11862757)9 Nakaki T. and Hishikawa K. (2002)
    942. Posttranscriptional regulation of human iNOS by the NO/cGMP pathway. (PubMed id 11181408)9 PAcrez-Sala D....Lamas S. (2001)
    943. Nitric oxide synthase immunoreactivity in human bladder carcinoma. (PubMed id 11477140)9 Shochina M....Ariel I. (2001)
    944. Altered mRNA expression of ecNOS and iNOS in myometrium and placenta from women with preeclampsia. (PubMed id 11327094)9 FaxAcn M....Kublickiene K.R. (2001)
    945. Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer. (PubMed id 11310211)9 Uotila P....HAorkAPnen P. (2001)
    946. Placental nitric oxide synthase (NOS) activity and nitric oxide (NO) production in normal pregnancy, pre-eclampsia and eclampsia. (PubMed id 11166745)9 Shaamash A.H....El-Dien H.M. (2001)
    947. [A quantitative pathological study on angiogenesis, vascular endothelial growth factor and inducible nitric oxide synthase in astrocytomas] (PubMed id 11866952)9 Bian X....Liu F. (2001)
    948. Thyrocyte release of asymmetric dimethylarginine does not account for human thyrocyte inhibition of endothelial cell cyclic GMP. (PubMed id 10802528)9 Millatt L.J....Whitley G.S. (2000)
    949. Expression and relationship between endothelin-1 messenger ribonucleic acid (mRNA) and inducible/endothelial nitric oxide synthase mRNA isoforms from normal and preeclamptic placentas. (PubMed id 10852470)9 Napolitano M....Lanzone A. (2000)
    950. Inhibition by parthenolide of phorbol ester-induced t ranscriptional activation of inducible nitric oxide synthase gene in a human mo nocyte cell line THP-1. (PubMed id 10874135)9 Fukuda K....Fujiwara H. (2000)
    951. Expression of inducible nitric oxide synthase in healthy pleura and in malignant mesothelioma. (PubMed id 10970689)9 Soini Y....Kinnula V. (2000)
    952. Effects of XW630 on cell proliferation, iNOS activity, and cGMP content in human osteoblast-like cell line TE85. (PubMed id 11324428)9 Sun L....Liu J.S. (2000)
    953. Oxygen tension limits nitric oxide synthesis by activated macrophages. (PubMed id 10970783)9 McCormick C.C....Calero M. (2000)
    954. Site-specific lesion formation, inflammation and indu cible nitric oxide synthase expression by indomethacin in the rat intestine. (PubMed id 10675738)9 Evans S.M....Whittle B.J. (2000)
    955. Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas. (PubMed id 10873093)9 Vakkala M....Soini Y. (2000)
    956. Variants of NOS1, NOS2, and NOS3 genes in asthmatics. (PubMed id 10673365)9 Gao P.S....Hopkin J.M. (2000)
    957. Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis. (PubMed id 10329044)9 GarbA!n H.J. and Bonavida B. (1999)
    958. Inducible nitric oxide synthase (iNOS) expression may predict distant metastasis in human melanoma. (PubMed id 10188914)9 Tschugguel W....Pehamberger H. (1999)
    959. Frequent expression of inducible nitric oxide synthase in esophageal squamous cell carcinomas. (PubMed id 10339659)9 Tanaka H....Makuuchi H. (1999)
    960. Downregulation of endothelin-1 by interleukin-4 during gastric ulcer healing. (PubMed id 10491337)9 Slomiany B.L....Slomiany A. (1999)
    961. The effects of two new antagonists of secretory PLA2 on TNF, iNOS, and COX-2 expression in activated macrophages. (PubMed id 10588517)9 Baek S.H....Kwun K.B. (1999)
    962. Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages. (PubMed id 10405759)9 Paul A....Plevin R. (1999)
    963. Expression and localization of the inducible isoform of nitric oxide synthase in nasal polyp epithelium. (PubMed id 9515595)9 Watkins D.N....Thompson P.J. (1998)
    964. VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR). (PubMed id 9837777)9 Kroll J. and Waltenberger J. (1998)
    965. Differential expression of nitric oxide synthase isoforms in form-deprived chick eyes. (PubMed id 9663848)9 Fujii S....Saijoh K. (1998)
    966. Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis. (PubMed id 9870873)9 Melchiorri C....Facchini A. (1998)
    967. An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase. (PubMed id 9368047)9 Salerno J.C....Gross S.S. (1997)
    968. N omega-propargyl-L-arginine and N omega-hydroxy-N omega-propargyl-L-arginine are inhibitors, but not inactivators, of neuronal and macrophage nitric oxide synthases. (PubMed id 9313865)9 Fast W....Silverman R.B. (1997)
    969. Immunohistochemical localization of nitric oxide synthase in normal human skin: expression of endothelial-type and inducible-type nitric oxide synthase in keratinocytes. (PubMed id 9065701)9 Shimizu Y....Ueda H. (1997)
    970. Molecular pathology of cerebral ischemia: delayed gene expression and strategies for neuroprotection. (PubMed id 9616775)9 Iadecola C. and Ross M.E. (1997)
    971. Myocardial contractile effects of L-arginine in the h uman allograft. (PubMed id 9137232)9 Paulus W.J....Drexler H. (1997)
    972. Heme iron reduction and catalysis by a nitric oxide synthase heterodimer containing one reductase and two oxygenase domains. (PubMed id 8631749)9 Siddhanta U....Stuehr D.J. (1996)
    973. Removal of constitutive and inducible nitric oxide synthase-active compounds in a modified hemodiafiltration with on-line production of substitution fluid: the contribution of convection and diffusion. (PubMed id 9029246)9 Arese M....Canaud B. (1996)
    974. Characterization of hepatic nitric oxide synthase: identification as the cytokine-inducible form primarily regulated by oxidants. (PubMed id 8700134)9 Duval D.L....Billings R.E. (1996)
    975. Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis. (PubMed id 7559438)9 Abu-Soud H.M....Stuehr D.J. (1995)
    976. Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension. (PubMed id 7664438)9 Mehta S....Levy R.D. (1995)
    977. Nitric oxide activates cyclooxygenase enzymes. (PubMed id 7688473)9 Salvemini D....Needleman P. (1993)
    978. Autoantibodies from schizophrenia patients induce cer ebral cox-1/iNOS mRNA expression with NO/PGE2/MMP-3 production. (PubMed id 19835666)9 Ganzinelli S....Sterin-Borda L. (2010)
    979. IL-27 inhibits OSM-mediated TNF-alpha and iNOS gene e xpression in microglia. (PubMed id 20468050)9 Baker B.J....Benveniste E.N. (2010)
    980. Pleiotropic effects of YC-1 selectively inhibit patho logical retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy. (PubMed id 20008515)9 DeNiro M....Al-Mohanna F.A. (2010)
    981. Development of nitrergic neurons in the nervous syste m of the locust embryo. (PubMed id 20148434)9 Stern M....Bicker G. (2010)
    982. Integrin-linked kinase is involved in TNF-alpha-induc ed inducible nitric-oxide synthase expression in myoblasts. (PubMed id 20135642)9 Tsou H.K....Chen Y.H. (2010)
    983. Induction of matrix metalloproteinase-1 and glioma ce ll motility by nitric oxide. (PubMed id 19629394)9 Pullen N.A. and Fillmore H.L. (2010)
    984. Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular r espiration and oxygen sparing. (PubMed id 20338478)9 Jiang H....Storme G.A. (2010)
    985. Human skin-derived mesenchymal stem cells as a source of VEGF and nitric oxide. (PubMed id 20035428)9 Salvolini E....Di Primio R. (2010)
    986. 3-Nitrotyrosine inhibits fibroblast-mediated collagen gel contraction and chemotaxis. (PubMed id 19443526)9 Sugiura H....Rennard S.I. (2009)
    987. Significant negative correlations between capillary e xpressed eNOS and Alzheimer lesion burden. (PubMed id 19660523)9 Jeynes B. and Provias J. (2009)
    988. Nitric oxide synthase gene therapy: progress and pros pects. (PubMed id 19463074)9 O'Connor D.M. and O'Brien T. (2009)
    989. Placental gene expression of calcitonin gene-related peptide and nitric oxide synthases in preeclampsia: effects of magnesium sulfate. (PubMed id 19441274)9 Ariza A.C....Halhali A. (2009)
    990. Functionally important role for arginase 1 in the air way hyperresponsiveness of asthma. (PubMed id 19286931)9 North M.L....Scott J.A. (2009)
    991. The protective effects of green tea extract against L -arginine toxicity to cultured human mesangial cells. (PubMed id 19194554)9 Shin B.C....Kim H.L. (2009)
    992. Preventive effect of co-administration of water conta ining magnesium ion on indomethacin induced lesions of gastric mucosa in adjuva nt-induced arthritis rat. (PubMed id 19122291)9 Nagai N....Hirano K. (2009)
    993. Re and (99m)Tc organometallic complexes containing pe ndant l-arginine derivatives as potential probes of inducible nitric oxide synt hase. (PubMed id 19081984)9 Oliveira B.L....Freire A.P. (2009)
    994. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules . (PubMed id 19699788)9 Kim E.H....Chun M. (2009)
    995. Phytochemicals from Flemingia vestita (Fabaceae) and Stephania glabra (Menispermeaceae) alter cGMP concentration in the cestode Rail lietina echinobothrida. (PubMed id 18854226)9 Das B....Ferro V.A. (2009)
    996. Basal nitric oxide synthase activity is a major deter minant of glomerular haemodynamics in humans. (PubMed id 18090547)9 Schlaich M.P....Schmieder R.E. (2008)
    997. Analysis of NO-synthase expression and clinical risk factors in human diabetic nephropathy. (PubMed id 18065828)9 Hohenstein B....Schmieder R.E. (2008)
    998. APOBEC and iNOS are not the main intracellular effectors of IFN-gamma-mediated inactivation of Hepatitis B virus replication. (PubMed id 18313151)9 Proto S....Naoumov N.V. (2008)
    999. Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. (PubMed id 18559982)9 Stadler K....Kadiiska M.B. (2008)
    1000. Recombinant arginine deiminase reduces inducible nitr ic oxide synthase iNOS-mediated neurotoxicity in a coculture of neurons and mic roglia. (PubMed id 18627024)9 Yu H.H....Shen L.J. (2008)
    1001. Solid tumor physiology and hypoxia-induced chemo/radio-resistance: novel strategy for cancer therapy: nitric oxide donor as a therapeutic enhancer. (PubMed id 18503779)9 Yasuda H. (2008)
    1002. Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kappaB inactivation. (PubMed id 18841975)9 Yun K.J....Lee K.T. (2008)
    1003. Nitroglycerin enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via nitric oxide pathway. (PubMed id 18430366)9 Huang L....Xiao Z.S. (2008)
    1004. NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma. Potential implications for immune regulation in high oxidative stress conditions. (PubMed id 18441394)9 Czesnikiewicz-Guzik M....Korbut R. (2008)
    1005. Induction of nitric oxide synthases in primary human cultured mast cells by IgE and proinflammatory cytokines. (PubMed id 18387520)9 Yip K.H....Lau H.Y. (2008)
    1006. Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resecti on in rats. (PubMed id 17882231)9 Kovanecz I....Gonzalez-Cadavid N. (2008)
    1007. Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. (PubMed id 18348730)9 Chowdhury T.T....Lee D.A. (2008)
    1008. Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. (PubMed id 17615555)9 Kuo C.L....Lin W.W. (2008)
    1009. Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III). (PubMed id 18325637)9 CarriA^n M.D....Entrena A. (2008)
    1010. Pregnancy enhances the innate immune response in expe rimental cutaneous leishmaniasis through hormone-modulated nitric oxide product ion. (PubMed id 18347075)9 Osorio Y....Travi B.L. (2008)
    1011. Intracerebroventricular injection of L-arginine induc es sedative and hypnotic effects under an acute stress in neonatal chicks. (PubMed id 18163184)9 Suenaga R....Furuse M. (2008)
    1012. Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia. (PubMed id 17298834)9 Ott C....Schmieder R.E. (2008)
    1013. Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression. (PubMed id 18528866)9 Rotondo R....Frumento G. (2008)
    1014. Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine. (PubMed id 18342305)9 Feng M....Xiong Y. (2008)
    1015. [Endothelial and inducible nitric oxide synthase expression in Venezuelan patients with pre-eclampsia] (PubMed id 18846773)9 AlemA!n I....RamA-rez C. (2008)
    1016. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. (PubMed id 17592514)9 Esposito G....Steardo L. (2007)
    1017. The enzymatic machinery for ADMA synthesis and degradation is fully expressed in human adipocytes. (PubMed id 17918140)9 Spoto B....Zoccali C. (2007)
    1018. Focused antibody response in plasma cell-infiltrated non-medullary (NOS) breast cancers. (PubMed id 17393302)9 Wang Y....Junghans R.P. (2007)
    1019. Anti-brain cholinergic auto antibodies from primary SjAPgren syndrome sera modify simultaneously cerebral nitric oxide and prostaglandin biosynthesis. (PubMed id 17920530)9 Orman B....Borda E. (2007)
    1020. Attenuation of experimental subarachnoid hemorrhage--induced cerebral vasospasm by the adenosine A2A receptor agonist CGS 21680. (PubMed id 17367066)9 Lin C.L....Kwan A.L. (2007)
    1021. Opioids induce renal abnormalities in tumor-bearing mice. (PubMed id 17220637)9 Arerangaiah R....Gupta K. (2007)
    1022. Influence of estrogen cycle on temporomandibular join t synovial membrane in rat with deviated mandible. (PubMed id 19845139)9 Kishimoto G....Soma K. (2007)
    1023. A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells. (PubMed id 17684157)9 Chabannes D....Cuturi M.C. (2007)
    1024. Sustained activation of nuclear factor-kappaB by reactive oxygen species is involved in the pathogenesis of stress-induced gastric damage in rats. (PubMed id 17452936)9 Jia Y.T....Xia Z.F. (2007)
    1025. Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma. (PubMed id 17717202)9 Singh D....O'Connor B.J. (2007)
    1026. NOS evaluations in human dental pulp-capping with MTA and calcium-hydroxide. (PubMed id 17897498)9 D'Arcangelo C....Caputi S. (2007)
    1027. Murine pre-eclampsia induced by unspecific activation of the immune system correlates with alterations in the eNOS and AT1 receptor expression in the kidneys and placenta. (PubMed id 17129602)9 Schmid M....Zenclussen A.C. (2007)
    1028. Irradiation at 634 nm releases nitric oxide from human monocytes. (PubMed id 17120165)9 LindgAYrd A....Soussi B. (2007)
    1029. Role of nitric oxide and reactive oxygen species in arthritis. (PubMed id 17017948)9 Cuzzocrea S. (2006)
    1030. [Highly selective inhibition of inducible nitric oxid e synthase in vitro by a tripeptide as a new arginine analog] (PubMed id 17062343)9 Sun F....Liu C.Q. (2006)
    1031. [Effect of puerarin on ADMA-DDAH system in human umbilical vein endothelial cells cultured with oxidized free radical] (PubMed id 17205823)9 Li J.X....Deng Z.H. (2006)
    1032. Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease. (PubMed id 17137520)9 Zhu F. and Qian C. (2006)
    1033. Interrelated overexpression of endothelial and inducible nitric oxide synthases, endothelin-1 and angiogenic factors in human papillary thyroid carcinoma. (PubMed id 16712675)9 Donckier J.E....Van Beneden R. (2006)
    1034. Green tea polyphenol epigallocatechin-3-gallate inhib its the expression of nitric oxide synthase and generation of nitric oxide indu ced by ultraviolet B in HaCaT cells. (PubMed id 16537022)9 Song X.Z....Xu A.E. (2006)
    1035. Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice. (PubMed id 16941682)9 GarcA-a-Ruiz I....SolA-s-Herruzo J.A. (2006)
    1036. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. (PubMed id 16427328)9 Whiteman M....Schantz J.T. (2006)
    1037. Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells. (PubMed id 16685418)9 Kim Y.A....Choi Y.H. (2006)
    1038. The peritoneal cavity is a distinct compartment of angiogenic molecular mediators. (PubMed id 16650862)9 Nachtsheim R....Howdieshell T.R. (2006)
    1039. Hydrogen peroxide acts as relaxing factor in human vascular smooth muscle cells independent of map-kinase and nitric oxide. (PubMed id 16720330)9 Palen D.I....Matrougui K. (2006)
    1040. High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis. (PubMed id 16806998)9 Wang C.T....Hou S.M. (2006)
    1041. Reperfusion liver injury induces down-regulation of eNOS and up-regulation of iNOS in lung tissues. (PubMed id 16980043)9 Lin H.I....Chen C.F. (2006)
    1042. The role of Rho-associated kinase in differential regulation by statins of interleukin-1beta- and lipopolysaccharide-mediated nuclear factor kappaB activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells. (PubMed id 16317111)9 Wei C.Y....Lin W.W. (2006)
    1043. Adenoviral-mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation. (PubMed id 16921253)9 Cooney R....O'Brien T. (2006)
    1044. Functional link between TNF biosynthesis and CaM-dependent activation of inducible nitric oxide synthase in RAW 264.7 macrophages. (PubMed id 16421203)9 Weber T.J....Thrall B.D. (2006)
    1045. Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with epidermal growth factor receptor expression. (PubMed id 15723947)9 Soo R....Hsieh W.S. (2005)
    1046. Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: a systematic review. (PubMed id 15993340)9 Willmot M....Bath P. (2005)
    1047. Regulation of nitric oxide synthase isoforms by estro gen in the human endometrium. (PubMed id 16210014)9 Han G....Khorram O. (2005)
    1048. GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo. (PubMed id 15778742)9 Alderton W.K....Knowles R.G. (2005)
    1049. Gender and estrogen supplementation increases severit y of experimental choroidal neovascularization. (PubMed id 15721623)9 Espinosa-Heidmann D.G....Cousins S.W. (2005)
    1050. Steroid cell tumors, not otherwise specified (NOS), in an accessory ovary: a case report and literature review. (PubMed id 15790472)9 Liu A.X....Song W.Q. (2005)
    1051. Anti-inflammatory effect of heme oxygenase 1: glycosylation and nitric oxide inhibition in macrophages. (PubMed id 15316927)9 Lin H.Y....Chen Y.C. (2005)
    1052. Catecholamines' enhancement of inducible nitric oxide synthase-induced nitric oxide biosynthesis involves CAT-1 and CAT-2A. (PubMed id 15976236)9 Lin W.C....Huang C.J. (2005)
    1053. The effect of intravesical Bacillus Calmette-Guerin i nstillations on the expression of inducible nitric oxide synthase in humans. (PubMed id 15964223)9 Mitropoulos D....Dimopoulos C. (2005)
    1054. Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells. (PubMed id 16144552)9 Thomas M.S....Taglialatela G. (2005)
    1055. Nitric oxide paradox in asthma. (PubMed id 15962094)9 Keller A.C....Russo M. (2005)
    1056. 5-aminoimidazole-4-carboxamide-1-beta-4-ribofurano side (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia. (PubMed id 16174294)9 Ayasolla K.R....Singh I. (2005)
    1057. Inducible nitric oxide synthase links NF-kappaB to PG E2 in polyunsaturated fatty acid altered fibroblast in-vitro wound healing. (PubMed id 16011805)9 Jia Y. and Turek J.J. (2005)
    1058. Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis. (PubMed id 15753535)9 Andresen L....Rask-Madsen J. (2005)
    1059. Beta-adrenergic receptor activation in immortalized human urothelial cells stimulates inflammatory responses by PKA-independent mechanisms. (PubMed id 16091148)9 Harmon E.B....Porter J.E. (2005)
    1060. Diethyldithiocarbamate inhibits iNOS expression in human lens epithelial cells stimulated by IFN-gamma and LPS. (PubMed id 15715934)9 Li D.X....Wu C.F. (2005)
    1061. Acetylbritannilatone suppresses NO and PGE2 synthesis in RAW 264.7 macrophages through the inhibition of iNOS and COX-2 gene expression. (PubMed id 15172177)9 Han M....Zhang D.Q. (2004)
    1062. Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells. (PubMed id 15179184)9 Zheng M....Grimm E.A. (2004)
    1063. Differential induction of TNF-alpha and NOS2 by mitogen-activated protein kinase signaling pathways during Mycobacterium bovis infection. (PubMed id 14667793)9 MAcndez-Samperio P....RamA-rez F.A. (2004)
    1064. Nitric oxide synthase inhibition: therapeutic potential in asthma. (PubMed id 15182209)9 Mulrennan S.A. and Redington A.E. (2004)
    1065. Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly(A) polymerase. (PubMed id 15693609)9 Murthy K.G....Salzman A.L. (2004)
    1066. Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53. (PubMed id 15520210)9 Cook T....Blumberg D. (2004)
    1067. Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes. (PubMed id 15030977)9 Teshima S....Okumura T. (2004)
    1068. Antioxidative response for nitric oxide production in breast carcinoma. (PubMed id 15375496)9 Karihtala P....Soini Y. (2004)
    1069. [Expression related to vascular endothelial growth factor C and induced nitride oxide synthesizase in lymph node micrometastasis of oral squamous cell carcinoma] (PubMed id 15656516)9 Xie Z.J....Zhang Y.K. (2004)
    1070. Expression of inducible nitric oxide synthase is increased in patients with heart failure due to ischemic disease. (PubMed id 15334196)9 Ferreiro C.R....da Luz P.L. (2004)
    1071. NOS isoforms in adult human osteocytes: multiple pathways of NO regulation? (PubMed id 15148557)9 Caballero-Alias A.M....Reeve J. (2004)
    1072. Renal disease in rats with type 2 diabetes is associated with decreased renal nitric oxide production. (PubMed id 15490111)9 Erdely A....Baylis C. (2004)
    1073. Interferon-gamma cooperates with Helicobacter pylori to induce iNOS-related apoptosis in AGS gastric adenocarcinoma cells. (PubMed id 15142623)9 Perfetto B....Donnarumma G. (2004)
    1074. Production of arginine by the kidney is impaired in a model of sepsis: early events following LPS. (PubMed id 15308488)9 Lortie M.J....Munger K.A. (2004)
    1075. Insulin feedback actions: complex effects involving isoforms of islet nitric oxide synthase. (PubMed id 15380928)9 Jimenez-Feltstrom J....Salehi A. (2004)
    1076. L-arginine promotes capacitation and acrosome reactio n in cryopreserved bovine spermatozoa. (PubMed id 15374626)9 O'Flaherty C....Srivastava S. (2004)
    1077. Maternal plasma from pregnant women with umbilical placental vascular disease does not affect endothelial cell mRNA expression of nitric oxide synthase. (PubMed id 15051034)9 Wang X....Trudinger B. (2004)
    1078. Mechanisms underlying growth hormone effects in augmenting nitric oxide production and protein tyrosine nitration during endotoxin challenge. (PubMed id 15044352)9 Elsasser T.H....Li C. (2004)
    1079. [Effect of Triptolide on TNFalpha-induced activation of NF-kappaB and expression of COX-2 and iNOS in human rheumatoid arthritis synovial fibroblasts] (PubMed id 15067740)9 Shao X.T....Zhang L.H. (2004)
    1080. Arginine metabolic enzymes, nitric oxide and infection. (PubMed id 15465793)9 Mori M. and Gotoh T. (2004)
    1081. Cloning of Mongolian gerbil cDNAs encoding inflammatory proteins, and their expression in glandular stomach during H. pylori infection. (PubMed id 15504246)9 Matsubara S....Wakabayashi K. (2004)
    1082. Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation. (PubMed id 15016631)9 Smirnova I.V....Goligorsky M.S. (2004)
    1083. Dual effects of caspase-1, interleukin-1 beta, tumour necrosis factor-alpha and nerve growth factor receptor in inflammatory myopathies. (PubMed id 12673888)9 Mackiewicz Z....Konttinen Y.T. (2003)
    1084. [Expression of nuclear factor-kappa B mRNA, inducible nitric oxide synthase and interleukin-6 in nasal polyp and its role] (PubMed id 15040111)9 Zhang H....Ma X.D. (2003)
    1085. [Expression changes of nitric oxide synthase mRNA of hypothalamus after sleep deprivation in rats] (PubMed id 12934610)9 Liu C.Y....Ruan F.M. (2003)
    1086. Inducible nitric oxide synthase-mediated proliferation of a T lymphoma cell line. (PubMed id 12620374)9 Barreiro Arcos M.L....Cremaschi G.A. (2003)
    1087. AQP1 and AQP3, psoriasin, and nitric oxide synthases 1-3 are inflammatory mediators in erythema toxicum neonatorum. (PubMed id 14521551)9 Marchini G....Nielsen S. (2003)
    1088. Nuclear factor-kappa B activation in skeletal muscle of patients with chronic heart failure: correlation with the expression of inducible nitric oxide synthase. (PubMed id 14555882)9 Adams V....Hambrecht R. (2003)
    1089. [Effect of magnesium supplementation on NO and NOS subtypes in cultured human umbilical vein endothelial Cells] (PubMed id 15600206)9 LA1 X. and Ruishu W. (2003)
    1090. L-arginine metabolism in myeloid cells controls T-lymphocyte functions. (PubMed id 12810105)9 Bronte V....Zanovello P. (2003)
    1091. Myocardial fibrosis blunts nitric oxide synthase-related preload reserve in human dilated cardiomyopathy. (PubMed id 12485814)9 Bronzwaer J.G....Paulus W.J. (2003)
    1092. Expression of inducible nitric oxide synthase in bone metastases. (PubMed id 12943630)9 Brennan P.A....Umar T. (2003)
    1093. Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway. (PubMed id 12847270)9 Chen C.W....Lin W.W. (2003)
    1094. Protein kinase C-eta (PKC-eta) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells. (PubMed id 14732335)9 Pham T.N....Richardson V.J. (2003)
    1095. Nitric oxide (NO) synthase mRNA expression and NO pro duction via muscarinic acetylcholine receptor-mediated pathways in the CEM, hum an leukemic T-cell line. (PubMed id 12628472)9 Kamimura Y....Kawashima K. (2003)
    1096. Impaired tubulointerstitial expression of endothelin-1 and nitric oxide isoforms in donor kidney biopsies with postischemic acute renal failure. (PubMed id 12973116)9 Mitterbauer C....Oberbauer R. (2003)
    1097. Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. (PubMed id 14638548)9 Dayoub H....Cooke J.P. (2003)
    1098. Akt as a mediator of secretory phospholipase A2 receptor-involved inducible nitric oxide synthase expression. (PubMed id 12574380)9 Park D.W....Baek S.H. (2003)
    1099. Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: a comparative study in gene-deficient mice. (PubMed id 12794844)9 de Hooge A.S....van den Berg W.B. (2003)
    1100. L-Arginine increases ischemic injury in wild-type mic e but not in iNOS-deficient mice. (PubMed id 12618354)9 Zhao X....Iadecola C. (2003)
    1101. Interactions between the nitric oxide and prostaglandin E2 biosynthetic pathways in human amnion-like WISH cells. (PubMed id 14568676)9 Biondi C....Vesce F. (2003)
    1102. Elevated serum nitric oxide levels in patients with inflammatory arthritis associated with co-expression of inducible nitric oxide synthase and protein kinase C-eta in peripheral blood monocyte-derived macrophages. (PubMed id 14719189)9 Pham T.N....Richardson V.J. (2003)
    1103. Is inducible nitric oxide synthase a target for chemo prevention? (PubMed id 12939472)9 Crowell J.A....Fay J.R. (2003)
    1104. Inhibition of IFN-gamma -induced STAT1 activation by 15- deoxy-Delta 12,14-prostaglandin J2. (PubMed id 12517740)9 Weber S.M....Corbett J.A. (2003)
    1105. Association between the expression of inducible nitric oxide synthase by chondrocytes and its nitric oxide-generating activity in adjuvant arthritis in rats. (PubMed id 12826065)9 Yonekura Y....Utsumi H. (2003)
    1106. Endothelin-1 inhibits TNF alpha-induced iNOS expression in 3T3-F442A adipocytes. (PubMed id 12839867)9 MAcrial-Kieny C....FAclActou M. (2003)
    1107. Increased inflammatory activity parallels increased b asal nitric oxide production and blunted response to nitric oxide in vivo in rh eumatoid arthritis. (PubMed id 12810424)9 Yki-JAorvinen H....Leirisalo-Repo M. (2003)
    1108. Estrogen reduces angiotensin II-induced nitric oxide synthase and NAD(P)H oxidase expression in endothelial cells. (PubMed id 12524222)9 Gragasin F.S....Davidge S.T. (2003)
    1109. Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck. (PubMed id 12404284)9 Franchi A....Gallo O. (2002)
    1110. Oxidative stress in gastric mucosa of asymptomatic humans infected with Helicobacter pylori: effect of bacterial eradication. (PubMed id 12485120)9 Felley C.P....Felley-Bosco E. (2002)
    1111. P38 mitogen-activated protein kinase inhibitor SB2035 80 has a bi-directional effect on iNOS expression and NO production. (PubMed id 12421638)9 Lahti A....Moilanen E. (2002)
    1112. Nitric oxide directly impairs intestinal barrier function. (PubMed id 11837790)9 Xu D.Z....Deitch E.A. (2002)
    1113. Aminoguanidine inhibits mitogen-activated protein kin ase and improves cardiac performance and cardiovascular remodeling in failing h earts of salt-sensitive hypertensive rats. (PubMed id 12473873)9 Kobayashi N....Matsuoka H. (2002)
    1114. Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line. (PubMed id 12144868)9 Banerjee T....Ziboh V.A. (2002)
    1115. [Expression of inducible nitric oxide synthase and basic fibroblast growth factor in supraglottic squamous cell carcinoma and their clinical significance] (PubMed id 12508542)9 Huang Z....Xia L.P. (2002)
    1116. Characterization of neurotransmitters and dopamine attenuation of inducible nitric oxide synthase in glioma cells. (PubMed id 12458038)9 Mazzio E....Soliman K.F. (2002)
    1117. The role of nitric oxide in ocular surface diseases. (PubMed id 12613978)9 Kim J.C....Yoon H.Y. (2002)
    1118. Decreased calcium-dependent constitutive nitric oxide synthase (cNOS) activity in prefrontal cortex in schizophrenia and depression. (PubMed id 12363386)9 Xing G....Post R.M. (2002)
    1119. Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. (PubMed id 11754077)9 Cassina P....Barbeito L. (2002)
    1120. Expression of endothelial and inducible nitric oxide synthase in benign and malignant lesions of the breast and measurement of nitric oxide using electron paramagnetic resonance spectroscopy. (PubMed id 12216084)9 Loibl S....Kaufmann M. (2002)
    1121. Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells. (PubMed id 12376366)9 Abraham N.G....Wolin M.S. (2002)
    1122. [The effects of hypoxia on the expression of inducibl e isoform of nitric oxide syntheses in nasal mucosal epithelial cells] (PubMed id 12412420)9 Jiang S....Zhao L. (2002)
    1123. Effect of magnesium lithospermate B on calcium and nitric oxide in endothelial cells upon hypoxia/reoxygenation. (PubMed id 12370098)9 Luo W.B....Wang Y.P. (2002)
    1124. Expression of inducible nitric oxide synthase during cisplatin-based chemotherapy for gastric cancer. (PubMed id 12182114)9 Ikeguchi M....Kaibara N. (2002)
    1125. Evidence of oxidative stress in human corneal diseases. (PubMed id 11850437)9 Buddi R....Brown D.J. (2002)
    1126. Mucinous differentiation in colonic adenocarcinoma is associated with a reduction in tumour-infiltrating lymphocytes. (PubMed id 11373104)9 Millar E.K....Lee C.S. (2001)
    1127. Inhibition of nitric oxide synthase abrogates lipopol ysaccharides-induced up-regulation of L-arginine uptake in rat alveolar macroph ages. (PubMed id 11375254)9 Hammermann R....RackAc K. (2001)
    1128. Immunohistochemical findings of nitric oxide synthase expression in urothelial transitional cell carcinoma including dysplasia. (PubMed id 11605048)9 Hayashi H....Kagawa S. (2001)
    1129. Attenuation of Helicobacter pylori endotoxin-provoked rat intestinal inflammation by selective inhibition of the inducible nitric oxide synthase. (PubMed id 11595474)9 Szepes Z....Whittle B.J. (2001)
    1130. 4-hydroxynonenal prevents NO production in vascular s mooth muscle cells by inhibiting nuclear factor-kappaB-dependent transcriptiona l activation of inducible NO synthase. (PubMed id 11451748)9 Hattori Y....Kasai K. (2001)
    1131. [Expression of the inducible isoform of nitric oxide synthase mRNA and the role in nasal polyps] (PubMed id 12762002)9 Jiang S....Yang Z. (2001)
    1132. Influence of hypoxia on nitric oxide synthase activity and gene expression in children with congenital heart disease: a novel pathophysiological adaptive mechanism. (PubMed id 11342476)9 Ferreiro C.R....Lemos Da Luz P. (2001)
    1133. Vascular endothelial growth factor synthesis in vascu lar smooth muscle cells is enhanced by 7-ketocholesterol and lysophosphatidylch oline independently of their effect on nitric oxide generation. (PubMed id 11730812)9 Dulak J....Dulakk J. (2001)
    1134. iNOS expression by activated neutrophils from patients with sepsis. (PubMed id 11167591)9 Tsukahara Y....Tanaka M. (2001)
    1135. Localization of 3-nitrotyrosine to rheumatoid and normal synovium. (PubMed id 11465704)9 Mapp P.I....Blake D.R. (2001)
    1136. Nitric oxide synthase inhibition as therapy for sepsis: a decade of promise. (PubMed id 12594864)9 Cobb J.P. (2001)
    1137. Mechanisms of synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells. (PubMed id 11730360)9 Kwon S....George S.C. (2001)
    1138. The time course of tumor necrosis factor-alpha, inducible nitric oxide synthase and vascular endothelial growth factor expression in an experimental model of chronic myocardial infarction in rats. (PubMed id 11399901)9 Heba G....DembiA8ska-KieA8 A. (2001)
    1139. [Relationship between expression of inducible nitric oxide synthase and of VEGF in oral carcinoma] (PubMed id 11930727)9 Zhao S....Ping F. (2001)
    1140. Time course of expression of three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats. (PubMed id 11255630)9 Niwa M....Yoshida J. (2001)
    1141. Increased expression of eNOS protein in omental versus subcutaneous adipose tissue in obese human subjects. (PubMed id 11439294)9 RydAcn M....Andersson K. (2001)
    1142. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5 -[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibi tors of neuronal nitric oxide synthase. (PubMed id 11472219)9 Hah J.M....Silverman R.B. (2001)
    1143. The role of nitric oxide in neoplastic transformation of C3H 10T1/2 embryonic fibroblasts. (PubMed id 11062159)9 Burnett T....Cooney R.V. (2000)
    1144. Coronary vasomotor dysfunction in the cardiac allograft: impact of different immunosuppressive regimens. (PubMed id 11117379)9 Weis M....von Scheidt W. (2000)
    1145. Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malaria. (PubMed id 10971704)9 Maneerat Y....Udomsangpetch R. (2000)
    1146. GnRH agonist-suppressed expression of nitric oxide synthases and generation of peroxynitrite in adenomyosis. (PubMed id 11098019)9 Kamada Y....Kudo T. (2000)
    1147. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. (PubMed id 11077049)9 Pan M.H....Lin J.K. (2000)
    1148. Oxygen regulation of rat hepatocyte iNOS gene expression. (PubMed id 10782904)9 Vargiu C....Colombatto S. (2000)
    1149. Differential and constitutive expression of neuronal, inducible, and endothelial nitric oxide synthase mRNAs and proteins in pathologically normal human tissues. (PubMed id 11020335)9 Park C.S....Cha Y.N. (2000)
    1150. Normal circulating adult human red blood cells contai n inactive NOS proteins. (PubMed id 10850643)9 Kang E.S....Acchiardo S.R. (2000)
    1151. Regulation of nitric oxide production by arginine metabolic enzymes. (PubMed id 10973788)9 Mori M. and Gotoh T. (2000)
    1152. Antagonism of LPS and IFN-gamma induced iNOS expression in human atrial endothelia by morphine, anandamide, and estrogen. (PubMed id 11324436)9 Fimiani C....Stefano G.B. (2000)
    1153. Acetaminophen inhibits iNOS gene expression in RAW 264.7 macrophages: differential regulation of NF-kappaB by acetaminophen and salicylates. (PubMed id 10860828)9 Ryu Y.S....Hur G.M. (2000)
    1154. Constitutive and inducible nitric oxide synthases after dynorphin-induced spinal cord injury. (PubMed id 10697245)9 Hu W.H....Jen M.F. (2000)
    1155. Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis. (PubMed id 11465019)9 Phul R.K....Smith M.E. (2000)
    1156. Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck. (PubMed id 9917057)9 Gavilanes J....Alvarez-Vicent J.J. (1999)
    1157. Conformationally-restricted arginine analogues as alt ernative substrates and inhibitors of nitric oxide synthases. (PubMed id 10428379)9 Lee Y....Silverman R.B. (1999)
    1158. Negative regulation by protein tyrosine phosphatase of IFN-gamma-dependent expression of inducible nitric oxide synthase. (PubMed id 10352298)9 DA-az-Guerra M.J....BoscA! L. (1999)
    1159. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. (PubMed id 10470105)9 Binder C....Oellerich M. (1999)
    1160. Membrane stabilization in harvested vein graft storage: effects on adhesion molecule expression and nitric oxide synthesis. (PubMed id 10485412)9 Vural K.M....Pinsky D.J. (1999)
    1161. Role for nitric oxide in the hyperpermeability and he modynamic changes induced by intravenous VEGF. (PubMed id 10067972)9 Tilton R.G....Williamson J.R. (1999)
    1162. N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. (PubMed id 10447959)9 Huang H....Silverman R.B. (1999)
    1163. Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine. (PubMed id 10383909)9 Ahn B....Ohshima H. (1999)
    1164. Human recombinant erythropoietin inhibits interleukin-1beta-stimulated nitric oxide and cyclic guanosine monophosphate production in cultured rat vascular smooth-muscle cells. (PubMed id 10193805)9 Kusano E....Asano Y. (1999)
    1165. The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer. (PubMed id 10521442)9 Daff S....Shimizu T. (1999)
    1166. Inducible nitric oxide synthase activity by interferon-gamma-producing cells in human radicular cysts. (PubMed id 10371908)9 Takeichi O....Saito T. (1999)
    1167. Characterization and regional distribution of nitric oxide synthase in the human brain during normal ageing. (PubMed id 10407101)9 Blum-Degen D....Gerlach M. (1999)
    1168. HIV-1 infection induces differentiation of immature neural cells through autocrine tumor necrosis factor and nitric oxide production. (PubMed id 10497105)9 ObregA^n E....MuA+oz-FernA!ndez M.A. (1999)
    1169. The role of nitric oxide in L-arginine-stimulated gro wth hormone release. (PubMed id 10442577)9 Fisker S....rgensen J.O. (1999)
    1170. Nitric oxide synthase expression and apoptotic cell death in brains of AIDS and AIDS dementia patients. (PubMed id 10199221)9 Vincent V.A....Van Dam A.M. (1999)
    1171. Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure. (PubMed id 9851365)9 Adams V....Hambrecht R. (1998)
    1172. Enhanced expression of inducible nitric oxide synthase in chronic gastritis with intestinal metaplasia. (PubMed id 9802453)9 Tatemichi M....Esumi H. (1998)
    1173. Inhibition of nuclear factor kappa B attenuates proinflammatory cytokine and inducible nitric-oxide synthase expression in postischemic myocardium. (PubMed id 9545547)9 Chandrasekar B....Freeman G.L. (1998)
    1174. Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation. (PubMed id 9778124)9 Odrcich M.J....Brien J.F. (1998)
    1175. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. (PubMed id 9554441)9 Gallo O....Ziche M. (1998)
    1176. Structural requirements for human inducible nitric oxide synthase substrates and substrate analogue inhibitors. (PubMed id 9521739)9 Grant S.K....Kozarich J.W. (1998)
    1177. Cyclic GMP and cGMP-binding phosphodiesterase are required for interleukin-1-induced nitric oxide synthesis in human articular chondrocytes. (PubMed id 9765278)9 Geng Y....Lotz M. (1998)
    1178. Expression of inducible nitric oxide synthase and inflammatory cytokines in alveolar macrophages of ARDS following sepsis. (PubMed id 9631804)9 Kobayashi A....Ashihara T. (1998)
    1179. Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo. (PubMed id 9740187)9 Shears L.L....Tzeng E. (1998)
    1180. Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-gamma in HaCaT keratinocytes: implications for the model of cutaneous wound repair. (PubMed id 9856818)9 Frank S....Pfeilschifter J. (1998)
    1181. HMN-1180, a small molecule inhibitor of neuronal nitric oxide synthase. (PubMed id 9864293)9 Nishio M....Hidaka H. (1998)
    1182. Placental nitric oxide production and umbilical artery vascular impedance in early pregnancy. (PubMed id 9572226)9 Lees C....Campbell S. (1998)
    1183. Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease. (PubMed id 9237172)9 DueA+as-Gonzalez A....Rodriguez-Commes J. (1997)
    1184. Inducible nitric oxide synthase and proinflammatory cytokine expression by human keratinocytes during acute urticaria. (PubMed id 9392005)9 BAccherel P.A....Arock M. (1997)
    1185. Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters. (PubMed id 9288162)9 Silverman R.B....Martasek P. (1997)
    1186. NO synthase isozymes have distinct substrate binding sites. (PubMed id 9376373)9 Fan B....Rousseau D.L. (1997)
    1187. Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis. (PubMed id 9122229)9 Hooper D.C....Koprowski H. (1997)
    1188. Activated astrocytes induce nitric oxide synthase-2 in cerebral endothelium via tumor necrosis factor alpha. (PubMed id 9419012)9 Shafer R.A. and Murphy S. (1997)
    1189. Aseptic loosening of total hip replacement. Macrophage expression of inducible nitric oxide synthase and cyclo-oxygenase-2, together with peroxynitrite formation, as a possible mechanism for early prosthesis failure. (PubMed id 9180331)9 Hukkanen M....Polak J.M. (1997)
    1190. Effect of nitric oxide synthase inhibition on renal h emodynamics in humans: reversal by L-arginine. (PubMed id 9124393)9 Wolzt M....Krejcy K. (1997)
    1191. Differential induction of constitutive and inducible nitric oxide synthases by distinct inflammatory stimuli in bovine aortic endothelial cells. (PubMed id 9099990)9 Kaku Y....Ikeda M. (1997)
    1192. Renal and systemic nitric oxide synthesis in rats with renal mass reduction. (PubMed id 9211360)9 Aiello S....Remuzzi G. (1997)
    1193. Effect of cyclic GMP-dependent vasodilators on the expression of inducible nitric oxide synthase in vascular smooth muscle cells: role of cyclic AMP. (PubMed id 8904645)9 Boese M....Schini-Kerth V. (1996)
    1194. Further evidence of the presence of constitutive and inducible nitric oxide synthase isoforms in human platelets. (PubMed id 8656650)9 Chen L.Y. and Mehta J.L. (1996)
    1195. Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. (PubMed id 8875487)9 Hino A....Macdonald R.L. (1996)
    1196. Regulation of inducible nitric oxide synthase in hepatic sinusoidal endothelial cells. (PubMed id 8770041)9 Rockey D.C. and Chung J.J. (1996)
    1197. Inhibition by antioxidants of nitric oxide synthase expression in murine macrophages: role of nuclear factor kappa B and interferon regulatory factor 1. (PubMed id 8864559)9 Hecker M....Busse R. (1996)
    1198. Analysis of substrate-induced electronic, catalytic, and structural changes in inducible NO synthase. (PubMed id 8639550)9 Sennequier N. and Stuehr D.J. (1996)
    1199. Role of tetrahydrobiopterin availability in the regulation of nitric-oxide synthase expression in human mesangial cells. (PubMed id 8662883)9 Saura M....Lamas S. (1996)
    1200. Differential activity of nitric oxide synthase in human nasal mucosa and polyps. (PubMed id 8777951)9 Ramis I....Bulbena O. (1996)
    1201. Electron paramagnetic resonance spectroscopy of the h eme domain of inducible nitric oxide synthase: binding of ligands at the argini ne site induces changes in the heme ligation geometry. (PubMed id 8672462)9 Salerno J.C....Masters B.S. (1996)
    1202. Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon-gamma. (PubMed id 8613707)9 Zhang X....Murphy W.J. (1996)
    1203. Carbon monoxide: an endogenous modulator of the nitri c oxide-cyclic GMP signaling system. (PubMed id 8608001)9 Ingi T....Ronnett G.V. (1996)
    1204. Increased nitric oxide synthase expression in arterial vessels of cirrhotic rats with ascites. (PubMed id 8938184)9 Morales-Ruiz M....Arroyo V. (1996)
    1205. Differentiation-dependent effects of IL-1 and TGF-beta on human articular chondrocyte proliferation are related to inducible nitric oxide synthase expression. (PubMed id 7535818)9 Blanco F.J....Lotz M. (1995)
    1206. Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. (PubMed id 7536934)9 Wu C.C....Vane J.R. (1995)
    1207. Vesnarinone inhibits induction of nitric oxide syntha se in J774 macrophages and rat cardiac myocytes in culture. (PubMed id 7585804)9 Hattori Y....Shimoda S. (1995)
    1208. Human placental and fetal membrane nitric oxide synth ase activity before, during and after labour at term. (PubMed id 8743155)9 Di Iulio J.L....Brennecke S.P. (1995)
    1209. N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases. (PubMed id 7540822)9 Reif D.W. and McCreedy S.A. (1995)
    1210. Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. (PubMed id 7530002)9 Brouet I. and Ohshima H. (1995)
    1211. Cycloheximide induces nitric oxide synthase mRNA in v ascular smooth muscle cells by prolonging mRNA lifetime. (PubMed id 8595383)9 Hattori Y. and Gross S.S. (1995)
    1212. The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up-regulated neuronal nitric oxide synthase. (PubMed id 7500055)9 Amin A.R....Abramson S.B. (1995)
    1213. Regulation of human placental fetal vessel tone: role of nitric oxide. (PubMed id 8743139)9 King R.G....Brennecke S.P. (1995)
    1214. Dexamethasone differentially affects interleukin 1 beta- and cyclic AMP-induced nitric oxide synthase mRNA expression in renal mesangial cells. (PubMed id 7528007)9 Kunz D....Pfeilschifter J. (1994)
    1215. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. (PubMed id 7523409)9 Garvey E.P....Furfine E.S. (1994)
    1216. Towards achieving the Health of the Nation target for cervical cancer: accuracy of cancer registration. (PubMed id 8037953)9 Lancaster G....Woodman C. (1994)
    1217. Cathepsin D in invasive ductal NOS breast carcinoma as defined by immunohistochemistry. No correlation with survival at 5 years. (PubMed id 1332483)9 Domagala W....Osborn M. (1992)
    1218. Vimentin expression appears to be associated with poor prognosis in node-negative ductal NOS breast carcinomas. (PubMed id 1701960)9 Domagala W....Osborn M. (1990)
    1219. (PubMed id 20148433)9 
    1220. Inhibition of L-arginine metabolizing enzymes by L-ar ginine-derived advanced glycation end products. (PubMed id 20216951)9 Lai Y.L....Ohshima H. (2010)
    1221. Reactive oxygen and nitrogen species regulate inducib le nitric oxide synthase function shifting the balance of nitric oxide and supe roxide production. (PubMed id 19932078)9 Sun J....Zweier J.L. (2010)
    1222. Heme oxygenase-1 mediates nicotine- and lipopolysacch aride-induced expression of cyclooxygenase-2 and inducible nitric oxide synthas e in human periodontal ligament cells. (PubMed id 20470258)9 Pi S.H....Kim E.C. (2010)
    1223. Neurodegeneration and increased production of nitroty rosine, nitric oxide synthase, IFN-gamma and S100beta protein in the spinal cor d of IL-12p40-deficient mice infected with Trypanosoma cruzi. (PubMed id 19923851)9 Bombeiro A.L....Alvarez J.M. (2010)
    1224. Increased asymmetric dimethylarginine in severe falci parum malaria: association with impaired nitric oxide bioavailability and fatal outcome. (PubMed id 20421938)9 Yeo T.W....Anstey N.M. (2010)
    1225. Roles of COX inhibition in pathogenesis of NSAID-indu ced small intestinal damage. (PubMed id 20074562)9 Takeuchi K....Satoh H. (2010)
    1226. Exposure to polychlorinated biphenyls enhances lipid peroxidation in human normal peritoneal and adhesion fibroblasts: a potential r ole for myeloperoxidase. (PubMed id 20067832)9 Saed G.M....Abu-Soud H.M. (2010)
    1227. A subcutaneous mandibulotomy approach for a salivary clear cell carcinoma of the retromolar trigone. (PubMed id 18696176)9 Fennessy B.G....Timon C. (2010)
    1228. Tumor necrosis factor and interferon-gamma down-regul ate Klotho in mice with colitis. (PubMed id 20004202)9 Thurston R.D....Ghishan F.K. (2010)
    1229. Dimethylfumarate inhibits microglial and astrocytic i nflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha a nd IL-6 in an in-vitro model of brain inflammation. (PubMed id 20482831)9 Wilms H....Lucius R. (2010)
    1230. Targeted inhibition of inducible nitric oxide synthas e inhibits growth of human melanoma in vivo and synergizes with chemotherapy. (PubMed id 20215556)9 Sikora A.G....Overwijk W.W. (2010)
    1231. Proangiogenetic molecules, hypoxia-inducible factor-1 alpha and nitric oxide synthase isoforms in ovarian endometriotic cysts. (PubMed id 20473769)9 Goteri G....Ciavattini A. (2010)
    1232. Production and scavenging of nitric oxide by barley r oot mitochondria. (PubMed id 20185408)9 Gupta K.J. and Kaiser W.M. (2010)
    1233. The protective effects of Polygonum multiflorum stilb eneglycoside preconditioning in an ischemia/reperfusion model of HUVECs. (PubMed id 20228828)9 Liu L.P....He M. (2010)
    1234. Nicotine enhances skin necrosis and expression of inf lammatory mediators in a rat pressure ulcer model. (PubMed id 19673871)9 Tsutakawa S....Nakahata N. (2009)
    1235. Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors. (PubMed id 19117642)9 LA^pez Cara L.C....Entrena A. (2009)
    1236. Beta-carotene prevents ozone-induced proinflammatory markers in murine skin. (PubMed id 19651793)9 Valacchi G....Davis P.A. (2009)
    1237. Role of immunoexpression of nitric oxide synthases by Hodgkin and Reed-Sternberg cells on apoptosis deregulation and on clinical outcome of classical Hodgkin lymphoma. (PubMed id 18830569)9 Campos A.H....Soares F.A. (2009)
    1238. Induction of endostatin expression in meniscal fibroc hondrocytes by co-culture with endothelial cells. (PubMed id 18839188)9 Hoberg M....Rudert M. (2009)
    1239. Curcumin prevents shock-wave lithotripsy-induced rena l injury through inhibition of nuclear factor kappa-B and inducible nitric oxid e synthase activity in rats. (PubMed id 19340419)9 Bas M....Tasci A.I. (2009)
    1240. Galactosyl derivative of N(omega)-nitro-L-arginine: s tudy of antiproliferative activity on human thyroid follicular carcinoma cells. (PubMed id 19650107)9 Melisi D....Rimoli M.G. (2009)
    1241. Protective effects of kaempferol against endothelial damage by an improvement in nitric oxide production and a decrease in asymmetri c dimethylarginine level. (PubMed id 19549512)9 Xiao H.B....Sun Z.L. (2009)
    1242. Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury. (PubMed id 19038279)9 Jung M....Sola A. (2009)
    1243. Bipartite vectors for co-expression of a growth facto r cDNA and short hairpin RNA against an apoptotic gene. (PubMed id 19554613)9 Li F. and Mahato R.I. (2009)
    1244. Ecabet sodium induces neuronal nitric oxide synthase- derived nitric oxide synthesis and gastric adaptive relaxation in the human sto mach. (PubMed id 19685003)9 Matsumoto Y....Chayama K. (2009)
    1245. Nitric oxide as an endogenous peripheral modulator of visceral sensory neuronal function. (PubMed id 19494147)9 Page A.J....Blackshaw L.A. (2009)
    1246. Capnellene, a natural marine compound derived from so ft coral, attenuates chronic constriction injury-induced neuropathic pain in ra ts. (PubMed id 19663884)9 Jean Y.H....Wen Z.H. (2009)
    1247. Mycobacterium bovis with different genotypes and from different hosts induce dissimilar immunopathological lesions in a mouse model of tuberculosis. (PubMed id 19659779)9 Aguilar LeA^n D....HernA!ndez Pando R. (2009)
    1248. Differential regulation of inducible nitric oxide syn thase and cyclooxygenase-2 expression by superoxide dismutase in lipopolysaccha ride stimulated RAW 264.7 cells. (PubMed id 19478557)9 Lee J.A....Park J.S. (2009)
    1249. Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in health y control subjects, healthy smokers, and COPD patients. (PubMed id 18719059)9 Brindicci C....Kharitonov S.A. (2009)
    1250. Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death. (PubMed id 19344390)9 Kato G.J....Hazen S.L. (2009)
    1251. Association between color doppler vascularity index, angiogenesis-related molecules, and clinical outcomes in gastric cancer. (PubMed id 19418489)9 Chen C.N....Lee P.H. (2009)
    1252. Chronic endurance exercise induces quadriceps nitrosative stress in patients with severe COPD. (PubMed id 18835959)9 Barreiro E....Roca J. (2009)
    1253. Ghrelin ameliorates colonic inflammation. Role of nit ric oxide and sensory nerves. (PubMed id 19617644)9 Konturek P.C....Konturek S.J. (2009)
    1254. Hypercholesterolaemia induces early renal lesions cha racterized by upregulation of MMP-9 and iNOS and ET(A)R: alleviated by a dual e ndothelin receptor antagonist CPU0213 and simvastatin. (PubMed id 19505368)9 Luo L....Dai D.Z. (2009)
    1255. Mechanism for quinolinic acid cytotoxicity in human a strocytes and neurons. (PubMed id 19526301)9 Braidy N....Guillemin G.J. (2009)
    1256. Bis-(3-hydroxyphenyl) diselenide inhibits LPS-stimulated iNOS and COX-2 expression in RAW 264.7 macrophage cells through the NF-kappaB inactivation. (PubMed id 19298695)9 Shin K.M....Lee K.T. (2009)
    1257. Bench-to-bedside review: the role of nitric oxide in sepsis. (PubMed id 20477340)9 De Cruz S.J....Sandrock C.E. (2009)
    1258. A benzoxazine derivative induces vascular endothelial cell apoptosis in the presence of fibroblast growth factor-2 by elevating NADP H oxidase activity and reactive oxygen species levels. (PubMed id 19539746)9 Zhao J....Miao J. (2009)
    1259. Nitroindazole compounds inhibit the oxidative activat ion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurot oxic pyridinium cations by human monoamine oxidase (MAO). (PubMed id 19669997)9 Herraiz T....GuillAcn H. (2009)
    1260. Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion. (PubMed id 19262227)9 Park J.K....Haller H. (2009)
    1261. Anti-inflammatory properties of the plant Verbascum m allophorum. (PubMed id 19828096)9 Speranza L....Grilli A. (2009)
    1262. Endothelial nitric oxide synthase gene polymorphisms and the renal hemodynamic response to L-arginine. (PubMed id 19037250)9 Cherney D.Z....Miller J.A. (2009)
    1263. Endothelial dysfunction in the early- and late-stage type-2 diabetic Goto-Kakizaki rat aorta. (PubMed id 19543853)9 Kazuyama E....Satoh K. (2009)
    1264. [The protective effect of nourishing yin and promotin g blood flow recipe on the aortic endothelium injury of diabetic rats] (PubMed id 19960948)9 Li B....Cao D. (2009)
    1265. Factors affecting anti-inflammatory effect of chitool igosaccharides in lipopolysaccharides-induced RAW264.7 macrophage cells. (PubMed id 19846296)9 Lee S.H....Je J.Y. (2009)
    1266. Alternatively activated and immunoregulatory monocyte s in human filarial infections. (PubMed id 19456233)9 Babu S....Nutman T.B. (2009)
    1267. Discovery of inducible nitric oxide synthase (iNOS) i nhibitor development candidate KD7332, part 1: Identification of a novel, poten t, and selective series of quinolinone iNOS dimerization inhibitors that are or ally active in rodent pain models. (PubMed id 19374401)9 Bonnefous C....Smith N.D. (2009)
    1268. Neuronal nitric oxide synthase: structure, subcellula r localization, regulation, and clinical implications. (PubMed id 19298861)9 Zhou L. and Zhu D.Y. (2009)
    1269. Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells. (PubMed id 18838070)9 Oh J.H....Kwon T.K. (2008)
    1270. Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo. (PubMed id 18348861)9 Schnorr O....Sies H. (2008)
    1271. Modulation of regional nitric oxide metabolism: blood glucose control or insulin? (PubMed id 18427775)9 Ellger B....Van den Berghe G. (2008)
    1272. Autoinhibition of endothelial nitric oxide synthase ( eNOS) in gut smooth muscle by nitric oxide. (PubMed id 18926858)9 Grider J.R. and Murthy K.S. (2008)
    1273. [New insights into arginase. Part II. Role in physiol ogy and pathology] (PubMed id 18480737)9 Mielczarek-Puta M....BaraA8czyk-KuA_ma A. (2008)
    1274. Preconditioning of carbon monoxide releasing molecule-derived CO attenuates LPS-induced activation of HUVEC. (PubMed id 18726003)9 Sun B....Shi G. (2008)
    1275. Nitration of respiratory epithelial cells by myeloperoxidase depends on extracellular nitrite. (PubMed id 18280259)9 Govindaraju K....Eidelman D.H. (2008)
    1276. Involvement of gaseous low molecular monoxides in the cutaneous reverse passive Arthus reaction: cytoprotective action of carbon monoxide. (PubMed id 18505425)9 Shimizu K....Sato S. (2008)
    1277. Nitric oxide synthase isoforms expression in fibrobla sts isolated from human normal peritoneum and adhesion tissues. (PubMed id 18440510)9 Jiang Z.L....Saed G.M. (2008)
    1278. Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats. (PubMed id 18265948)9 Celik S. and Erdogan S. (2008)
    1279. Suppression of lipopolysaccharide-induced of inducibl e nitric oxide synthase and cyclooxygenase-2 by Sanguis Draconis, a dragon's bl ood resin, in RAW 264.7 cells. (PubMed id 18060707)9 Choy C.S....Wang T.C. (2008)
    1280. A comparison of the effects of kaempferol and quercet in on cytokine-induced pro-inflammatory status of cultured human endothelial ce lls. (PubMed id 18394220)9 Crespo I....GonzA!lez-Gallego J. (2008)
    1281. Interaction between inflammation and angiogenesis during different stages of cervical carcinogenesis. (PubMed id 17936343)9 Mazibrada J....Gariglio M. (2008)
    1282. Palmitate-induced NO production has a dual action to reduce cell death through NO and accentuate cell death through peroxynitrite formation. (PubMed id 18191557)9 Rabkin S.W. and Klassen S.S. (2008)
    1283. Cytokine-induced enhancement of calcium-dependent glu tamate release from astrocytes mediated by nitric oxide. (PubMed id 18255223)9 Ida T....Ihara H. (2008)
    1284. Two autocrine pathways to regulate cyclic GMP synthesis in cultured human retinal pigment epithelial cells. (PubMed id 18437032)9 Diederen R.M....de Vente J. (2008)
    1285. Involvement of protein kinase C and not of NF kappa B in the modulation of macrophage nitric oxide synthase by tumor-derived phosphatidyl serine. (PubMed id 18292949)9 Calderon C.L....Lopez D.M. (2008)
    1286. Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia. (PubMed id 18070819)9 Maas R....BAPger R.H. (2008)
    1287. Anesthetic modulation of immune reactions mediated by nitric oxide. (PubMed id 18500613)9 Toda N....Hatano Y. (2008)
    1288. Eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappaB signaling pathway in lung epithelial cells. (PubMed id 19051345)9 Lee C.H....Ho T.Y. (2008)
    1289. BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase. (PubMed id 18178668)9 Tiso M....Stuehr D.J. (2008)
    1290. Janus kinase 3 inhibitor WHI-P154 in macrophages acti vated by bacterial endotoxin: differential effects on the expression of iNOS, C OX-2 and TNF-alpha. (PubMed id 18068105)9 Sareila O....Moilanen E. (2008)
    1291. Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes. (PubMed id 17703957)9 Stradner M.H....Graninger W.B. (2008)
    1292. The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning. (PubMed id 18300858)9 Lafuente N....SA!nchez-Ferrer C.F. (2008)
    1293. Asymmetric dimethylarginine induces TNF-alpha production via ROS/NF-kappaB dependent pathway in human monocytic cells and the inhibitory effect of reinioside C. (PubMed id 18295546)9 Zhang G.G....Li Y.J. (2008)
    1294. Photoreceptor oxidative damage in sympathetic ophthalmia. (PubMed id 18514610)9 Parikh J.G....Rao N.A. (2008)
    1295. Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes. (PubMed id 18417374)9 Chabane N....Fahmi H. (2008)
    1296. Possible role for nitric oxide dysregulation in critical illness myopathy. (PubMed id 17924542)9 Capasso M....Uncini A. (2008)
    1297. Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases. (PubMed id 18211830)9 Ginnan R....Jourd'heuil D. (2008)
    1298. Effect of using RNA interference to alter iNOS gene expression on the proliferation of tongue squamous cell carcinoma cell line Tca8113. (PubMed id 18406501)9 Chen W.L....Wang Y.J. (2008)
    1299. Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. (PubMed id 18339887)9 Singh R.P....Agarwal R. (2008)
    1300. Nitric oxide isoenzymes regulate lipopolysaccharide-enhanced insulin transport across the blood-brain barrier. (PubMed id 18187549)9 Banks W.A....Vo T.Q. (2008)
    1301. AH23848 accelerates inducible nitric oxide synthase degradation through attenuation of cAMP signaling in glomerular mesangial cells. (PubMed id 18039475)9 Lin Y.S....Lin T.H. (2008)
    1302. Astragalus polysaccharides: an effective treatment for diabetes prevention in NOD mice. (PubMed id 18924264)9 Chen W....Yu M.H. (2008)
    1303. Galantamine and carbon monoxide protect brain microvascular endothelial cells by heme oxygenase-1 induction. (PubMed id 18174021)9 Nakao A....Kanno S. (2008)
    1304. Dynamic determination of Ox-LDL-induced oxidative/nit rosative stress in single macrophage by using fluorescent probes. (PubMed id 18782627)9 Deng T....Zheng X. (2008)
    1305. Constitutive nitric oxide synthases in the heart from hypertrophy to failure. (PubMed id 18307746)9 Loyer X....Samuel J.L. (2008)
    1306. Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease. (PubMed id 18663495)9 Hancock D.B....Scott W.K. (2008)
    1307. Levels of asymmetric dimethylarginine, nitric oxide and lipid peroxidation markers in patients with end-stage renal disease having peritoneal dialysis treatment. (PubMed id 18457672)9 GAPAsmen A.Y....GA1mA1A9lA1 S. (2008)
    1308. NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas. (PubMed id 18593915)9 Engels K....Stauber R.H. (2008)
    1309. Influence of hyperoxia on skin vasomotor control in n ormothermic and heat-stressed humans. (PubMed id 17885027)9 Yamazaki F....Johnson J.M. (2007)
    1310. Short-term effect of the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxide synthase activity. (PubMed id 18200826)9 Ludolph B....Kleinbongard P. (2007)
    1311. Avocado soybean unsaponifiables (ASU) suppress TNF-alpha, IL-1beta, COX-2, iNOS gene expression, and prostaglandin E2 and nitric oxide production in articular chondrocytes and monocyte/macrophages. (PubMed id 17845860)9 Au R.Y....Frondoza C.G. (2007)
    1312. Inhibitory effects of endogenous L-arginine analogues on nitric oxide synthesis in platelets: role in platelet hyperaggregability in hypertension. (PubMed id 17973865)9 de Meirelles L.R....Brunini T.M. (2007)
    1313. Asymmetric dimethylarginine is increased in chronic thromboembolic pulmonary hypertension. (PubMed id 17872491)9 Skoro-Sajer N....Lang I.M. (2007)
    1314. Regulation by DDAH/ADMA pathway of lipopolysaccharide-induced tissue factor expression in endothelial cells. (PubMed id 17479195)9 Xin H.Y....Chen F.P. (2007)
    1315. Early changes in rectal nitric oxide and mucosal inflammatory mediators in Crohn's colitis in response to infliximab treatment. (PubMed id 17402996)9 Ljung T....HellstrAPm P.M. (2007)
    1316. Activation of peroxynitrite by inducible nitric-oxide synthase: a direct source of nitrative stress. (PubMed id 17369257)9 MarAcchal A....Santolini J. (2007)
    1317. The tragedy of TRIUMPH for nitric oxide synthesis inhibition in cardiogenic shock: where do we go from here? (PubMed id 17953472)9 Bailey A....Campbell C.L. (2007)
    1318. Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. (PubMed id 17487414)9 Cheung S. and Tai J. (2007)
    1319. Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat. (PubMed id 17287493)9 Ferrini M.G....Gonzalez-Cadavid N.F. (2007)
    1320. Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. (PubMed id 18274639)9 HAomAolAoinen M....Moilanen E. (2007)
    1321. Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells. (PubMed id 17277882)9 Tong X....Yao H. (2007)
    1322. Involvement of inducible nitric oxide synthase and receptor for advanced glycation end products in periapical granulomas. (PubMed id 17258631)9 Hama S....Ito K. (2007)
    1323. Low plasma concentrations of arginine and asymmetric dimethylarginine in premature infants with necrotizing enterocolitis. (PubMed id 17381965)9 Richir M.C....van Leeuwen P.A. (2007)
    1324. Topical application of neuronal nitric oxide synthase inhibitor accelerates cutaneous barrier recovery and prevents epidermal hyperplasia induced by barrier disruption. (PubMed id 17363920)9 Ikeyama K....Denda M. (2007)
    1325. Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils. (PubMed id 17119118)9 Jacobsen L.C....Borregaard N. (2007)
    1326. The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis. (PubMed id 17545942)9 Wheeler D.S....Zingarelli B. (2007)
    1327. Functional significance of hsp90 complexes with NOS and sGC in endothelial cells. (PubMed id 17641392)9 Antonova G....Catravas J.D. (2007)
    1328. Human serum albumin improves arterial dysfunction during early resuscitation in mouse endotoxic model via reduced oxidative and nitrosative stresses. (PubMed id 17991713)9 Meziani F....Andriantsitohaina R. (2007)
    1329. Prospective multi-center trial for the efficacy of ecabet sodium on the relief of dyspepsia in korean patients with chronic gastritis. (PubMed id 18299710)9 Yang Kim H....Hong W.S. (2007)
    1330. Effects of bacterial toxins on endothelial tight junc tion in vitro: a mechanism-based investigation. (PubMed id 20020957)9 Singh A.K....Gupta S. (2007)
    1331. Hydrogen sulfide downregulates the aortic L-arginine/nitric oxide pathway in rats. (PubMed id 17634203)9 Geng B....Du J. (2007)
    1332. Oxidative stress expression status associated to Helicobacter pylori virulence in gastric diseases. (PubMed id 17466292)9 Augusto A.C....Gurgueira S.A. (2007)
    1333. Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival. (PubMed id 17096347)9 Zell J.A....Anton-Culver H. (2007)
    1334. Nitric oxide in the injured spinal cord: synthases cr oss-talk, oxidative stress and inflammation. (PubMed id 17500094)9 Conti A....Tomasello F. (2007)
    1335. High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis. (PubMed id 17240121)9 Hayashi T....Iguchi A. (2007)
    1336. Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro. (PubMed id 17417610)9 Wu R....Haefliger I. (2007)
    1337. N-acetylcysteine inhibits induction of nitric oxide s ynthase in 3T3-L1 adipocytes. (PubMed id 18170962)9 Araki S....Shirahata A. (2007)
    1338. Systemic nitric oxide synthase inhibition improves co ronary flow reserve to adenosine in patients with significant stenoses. (PubMed id 17660388)9 Kaufmann P.A....Camici P.G. (2007)
    1339. [Over-expression of hypoxia-inducible factor-1 alpha increases angiogenesis of LNCaP cells] (PubMed id 18077909)9 Han Y.L....Zhu G.F. (2007)
    1340. Genistein restores caveolin-1 and AT-1 receptor expre ssion and vascular function in large vessels of ovariectomized hypertensive rat s. (PubMed id 17667142)9 Vera R....Duarte J. (2007)
    1341. When a mucocele is not a mucocele: adenocarcinoma NOS--a case report and review of the literature. (PubMed id 17682642)9 Closmann J.J. and Torske K.R. (2007)
    1342. Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis. (PubMed id 17472813)9 Guttman-Yassky E....Krueger J.G. (2007)
    1343. Expression of angiogenic factors in childhood B-cell precursor acute lymphoblastic leukemia. (PubMed id 17143492)9 Stachel D....Schmid I. (2007)
    1344. Linoleic acid-induced expression of inducible nitric oxide synthase and cyclooxygenase II via p42/44 mitogen-activated protein kinase and nuclear factor-kappaB pathway in retinal pigment epithelial cells. (PubMed id 17825288)9 Fang I.M....Chen M.S. (2007)
    1345. Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. (PubMed id 17977265)9 Jung C.S....Pluta R.M. (2007)
    1346. Evidence for in vivo scavenging by aminoguanidine of formaldehyde produced via semicarbazide-sensitive amine oxidase-mediated deamination. (PubMed id 17596537)9 Kazachkov M....Yu P.H. (2007)
    1347. The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. (PubMed id 17438334)9 Ziesche E....Muhl H. (2007)
    1348. Suppression of cytokine response by GATA inhibitor K-7174 via unfolded protein response. (PubMed id 17604001)9 Takano Y....Kitamura M. (2007)
    1349. [Regulatory role of hypoxia inducible factor-1alpha in the changes of contraction of vascular smooth muscle cell induced by hypoxia] (PubMed id 17996129)9 Zhang Y....Chen W. (2007)
    1350. NMDA receptor and iNOS are involved in the effects of ginsenoside Rg1 on hippocampal neurogenesis in ischemic gerbils. (PubMed id 17509226)9 Shen L. and Zhang J. (2007)
    1351. Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. (PubMed id 17384130)9 Rajesh M....Pacher P. (2007)
    1352. The role of constitutive and inducible nitric oxide synthase in the human brain after subarachnoid hemorrhage. (PubMed id 17369785)9 Berra L.V....Pasqualin A. (2007)
    1353. Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC. (PubMed id 16891102)9 Quagliaro L....Ceriello A. (2007)
    1354. Activated protein C suppresses adrenomedullin and ameliorates lipopolysaccharide-induced hypotension. (PubMed id 17558353)9 Gupta A....Grinnell B.W. (2007)
    1355. Inflammation and IGF-I activate the Akt pathway in breast cancer. (PubMed id 17096325)9 Prueitt R.L....Ambs S. (2007)
    1356. Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids. (PubMed id 16949893)9 Martens-Lobenhoffer J. and Bode-BAPger S.M. (2007)
    1357. [Expression analysis of different collagens and cytokines in cartilage cells derived from arthrotic hip and knee joints] (PubMed id 16821180)9 Hoberg M....Rudert M. (2006)
    1358. Inhibitors of inducible nitric oxide synthase prevent damage to human lens epithelial cells induced by interferon-gamma and lipopolysaccharide. (PubMed id 17015954)9 Nagai N....Ito Y. (2006)
    1359. Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. (PubMed id 16580779)9 Shen S.C....Chen Y.C. (2006)
    1360. Inducible nitric oxide synthase and cyclooxgenase-2 mediate protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells. (PubMed id 16616209)9 Tang X.Q....Chen P.X. (2006)
    1361. Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD. (PubMed id 16646959)9 RytilAo P....Kinnula V.L. (2006)
    1362. NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion. (PubMed id 16540395)9 ViA+as J.L....Hotter G. (2006)
    1363. Roles of nitric oxide synthase inhibition an