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NOS1 Gene

protein-coding   GIFtS: 71
GCID: GC12M117636

Nitric Oxide Synthase 1 (Neuronal)


(Previous symbol: NOS)
Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nitric Oxide Synthase 1 (Neuronal)1 2     bNOS2 3
NOS1 2     nNOS2 3
Constitutive NOS2 3     NOS Type I2 3
Neuronal NOS2 3     EC 1.14.13.393 8
Peptidyl-Cysteine S-Nitrosylase NOS12 3     IHPS12
N-NOS2 3     Nitric Oxide Synthase, Brain2
NC-NOS2 3     

External Ids:    HGNC: 78721   Entrez Gene: 48422   Ensembl: ENSG000000892507   OMIM: 1637315   UniProtKB: P294753   

Export aliases for NOS1 gene to outside databases

Previous GC identifers: GC12M116666 GC12M117169 GC12M117431 GC12M116060 GC12M116111 GC12M114660


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NOS1 Gene:
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide
from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes,
including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous
system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity
associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis,
and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle.
Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length
nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding
different isoforms (some testis-specific) have been found for this gene.(provided by RefSeq, Feb 2011)

GeneCards Summary for NOS1 Gene:
NOS1 (nitric oxide synthase 1 (neuronal)) is a protein-coding gene. Diseases associated with NOS1 include pyloric stenosis, and factitious disorder. GO annotations related to this gene include calmodulin binding and heme binding. An important paralog of this gene is NOS3.

UniProtKB/Swiss-Prot: NOS1_HUMAN, P29475
Function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In
the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has
nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR

summary for NOS1 Gene:
Neuronal nitric oxide synthase (nNOS), along with inducible nitric oxide synthase (iNOS) and endothelial
nitric oxide synthase (eNOS), catalyze the generation of nitric oxide and L-citrulline from L-arginine and
molecular oxygen. It is activated at concentrations of calcium greater than 100 nM and requires co-factors
of tetrahydrobiopterin, flavin adenine dinucleotide, flavin mononucleotide and NADPH for catalytic activity.
Transcriptional regulation of nNOS is very complex and the nNOS gene produces multiple mRNA transcripts
using alternate promoters, alternative splicing, cassette insertions/deletions, and varied sites for 3'-UTR
cleavage and polyadenylation. Some of these alterations lead to variation in amino acid sequence,
translating into nNOS isoforms with altered structural and functional properties. nNOS has been implicated
in a wide variety of physiological and pathological processes, including neurotransmission, neurotoxicity,
skeletal muscle contraction, sexual function, body fluid homeostasis and atherosclerosis. Consistent with
such wide involvement, nNOS is expressed in numerous tissues. The human gene encoding nNOS is localized to
chromosome 12q14.

Gene Wiki entry for NOS1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NOS1 gene promoter:
         CREB   AP-1   ATF-2   deltaCREB   c-Jun   STAT5A   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOS1 promoter sequence
   Search Chromatin IP Primers for NOS1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NOS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.22   Ensembl cytogenetic band:  12q24.22   HGNC cytogenetic band: 12q24.22

NOS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOS1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M117636:  view genomic region     (about GC identifiers)

Start:
117,645,947 bp from pter      End:
117,889,975 bp from pter
Size:
244,029 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NOS1_HUMAN, P29475 (See protein sequence)
Recommended Name: Nitric oxide synthase, brain  
Size: 1434 amino acids; 160970 Da
Cofactor: Heme group
Cofactor: Binds 1 FAD
Cofactor: Binds 1 FMN
Cofactor: Tetrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme
Subunit: Homodimer. Interacts with DLG4; the interaction possibly being prevented by the association between NOS1
and CAPON. Forms a ternary complex with CAPON and RASD1. Forms a ternary complex with CAPON and SYN1. Interacts
with ZDHHC23. Interacts with NOSIP; which may impair its synaptic location (By similarity). Interacts with HTR4.
Interacts with VAC14 (By similarity). Interacts with SLC6A4 (By similarity). Interacts (via N-terminus domain)
with DLG4 (via N-terminus tandem pair of PDZ domains) (By similarity)
Secondary accessions: E9PH30 O75713
Alternative splicing: 5 isoforms:  P29475-1   P29475-2   P29475-3   P29475-4   P29475-5   

Explore the universe of human proteins at neXtProt for NOS1: NX_P29475

Explore proteomics data for NOS1 at MOPED

Post-translational modifications: 

  • Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro) (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for NOS1 (P29475) (see all 38)
     VLEEFPS  GWYMGTE  LDITTPP  VFGLGSR 


    See NOS1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_000611.1  NP_001191142.1  NP_001191143.1  NP_001191147.1  

    ENSEMBL proteins: 
     ENSP00000320758   ENSP00000337459   ENSP00000339862  
    Reactome Protein details: P29475

    NOS1 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for NOS1
    OriGene MassSpec for NOS1
    OriGene Custom Protein Services for NOS1
    GenScript Custom Purified and Recombinant Proteins Services for NOS1
    Novus Biologicals NOS1 Protein
    Novus Biologicals NOS1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NOS1

    NOS1 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of NOS1
    R&D Systems Antibodies for NOS1 (nNOS)
    Cell Signaling Technology (CST) Antibodies for NOS1  (nNOS)
    OriGene Antibodies for NOS1
    OriGene Custom Antibody Services for NOS1
    Novus Biologicals NOS1 Antibodies
    Abcam antibodies for NOS1 (P29475, P35228)
    Cloud-Clone Corp. Antibodies for NOS1
    ThermoFisher Antibody for NOS1
    LSBio Antibodies in human, mouse, rat for NOS1

    NOS1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NOS1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NOS1
    Enzo Life Sciences assays for NOS1
    Cloud-Clone Corp. ELISAs for NOS1
    Cloud-Clone Corp. CLIAs for NOS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: Neuronal NOS
    Nitric oxide synthases

    Selected InterPro protein domains (see all 11):
     IPR017927 Fd_Rdtase_FAD-bd
     IPR001094 Flavdoxin
     IPR001478 PDZ
     IPR008254 Flavodoxin/NO_synth
     IPR012144 NOS_euk

    Graphical View of Domain Structure for InterPro Entry P29475

    ProtoNet protein and cluster: P29475

    Selected Blocks protein domains (see all 6):
    IPB001094 Flavodoxin signature
    IPB001433 Oxidoreductase FAD/NAD(P)-binding
    IPB001478 PDZ/DHR/GLGF domain
    IPB001709 Flavoprotein pyridine nucleotide cytochrome reductase signature
    IPB003097 FAD-binding


    UniProtKB/Swiss-Prot: NOS1_HUMAN, P29475
    Domain: The PDZ domain in the N-terminal part of the neuronal isoform participates in protein-protein interaction,
    and is responsible for targeting nNos to synaptic membranes in muscles. Mediates interaction with VAC14 (By
    similarity)
    Similarity: Belongs to the NOS family
    Similarity: Contains 1 FAD-binding FR-type domain
    Similarity: Contains 1 flavodoxin-like domain
    Similarity: Contains 1 PDZ (DHR) domain


    NOS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NOS1_HUMAN, P29475
    Function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In
    the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has
    nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR
    Catalytic activity: 2 L-arginine + 3 NADPH + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H(2)O
    Enzyme regulation: Stimulated by calcium/calmodulin. Inhibited by n-Nos-inhibiting protein (PIN) which may prevent
    the dimerization of the protein. Inhibited by NOSIP

         Genatlas biochemistry entry for NOS1:
    nitric oxide synthase 1,constitutive by expressed,neuronal,putative susceptibility gene for infantile pyloric
    stenosis,widely expressed with a high expression in skeletal muscle

         Enzyme Number (IUBMB): EC 1.14.13.391 2

         Gene Ontology (GO): Selected molecular function terms (see all 16):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003958NADPH-hemoprotein reductase activity IBA--
    GO:0004517nitric-oxide synthase activity ISS--
    GO:0005506iron ion binding IEA--
    GO:0005515protein binding IPI11149895
    GO:0005516calmodulin binding IEA--
         
    NOS1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NOS1:
     Decreased viability after Chla 

         Selected MGI mutant phenotypes (inferred from 6 alleles(MGI details for Nos1) (see all 22):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  digestive/alimentary 
     endocrine/exocrine gland  growth/size/body  hematopoietic system  homeostasis/metabolism  immune system 
     liver/biliary system  mortality/aging  muscle  nervous system  no phenotypic analysis 

    NOS1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for NOS1: Nos1tm1Plh Nos1tm1Enik Nos1tm2Plh

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NOS1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NOS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOS1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOS1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat NOS1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NOS1 (see all 74):
    hsa-miR-4254 hsa-miR-146a hsa-miR-15a hsa-miR-938 hsa-miR-371-5p hsa-miR-502-3p hsa-miR-149 hsa-miR-3116
    SwitchGear 3'UTR luciferase reporter plasmidNOS1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NOS1
    Predesigned siRNA for gene silencing in human, mouse, rat NOS1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NOS1

    Clone
    Products:
         
    OriGene clones in human, mouse for NOS1 (see all 7)
    OriGene ORF clones in mouse, rat for NOS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): NOS1 (NM_000620)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOS1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NOS1
    Browse ESI BIO Cell Lines and PureStem Progenitors for NOS1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOS1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NOS1_HUMAN, P29475: Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine (By
    similarity). Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by
    associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol4
    endoplasmic reticulum4
    cytoskeleton3
    mitochondrion2
    nucleus2
    extracellular1

    Gene Ontology (GO): Selected cellular component terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001917photoreceptor inner segment ISS17027776
    GO:0005737cytoplasm TAS17892502
    GO:0005829cytosol TAS--
    GO:0005856cytoskeleton ISS7545544
    GO:0016529sarcoplasmic reticulum IDA9892689

    NOS1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NOS1 About   (see all 33)  
    See pathways by source

    SuperPathContained pathways About
    1Arginine and proline metabolism
    Arginine and proline metabolism
    citrulline-nitric oxide cycle0.00
    superpathway of citrulline metabolism0.00
    2Amyotrophic lateral sclerosis (ALS)
    Amyotrophic lateral sclerosis (ALS)0.63
    Amyotrophic lateral sclerosis (ALS)0.63
    3Alzheimer's disease
    Alzheimers Disease0.44
    Alzheimer's disease0.44
    4Monoamine Transport
    Monoamine Transport
    Serotonin Transporter Activity0.00
    5Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for NOS1 (see all 9)
        Cellular Effects of Sildenafil
    Muscular Dystrophies and Dystrophin-Glycoprotein Complex
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Sertoli-Sertoli Cell Junction Dynamics
    Endothelin-1 Signaling Pathway

    2 Cell Signaling Technology (CST) Pathways for NOS1
        Neuroscience
    PI3K / Akt Signaling

    3 GeneGo (Thomson Reuters) Pathways for NOS1
        Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
    Apoptosis and survival Anti-apoptotic action of nuclear ESR1 and ESR2
    NO-dependent CFTR activation (normal and CF)

    Selected BioSystems Pathways for NOS1 (see all 9)
        Myometrial Relaxation and Contraction Pathways
    Spinal Cord Injury
    Amyotrophic lateral sclerosis (ALS)
    Effects of nitric oxide
    Monoamine Transport

    2 Reactome Pathways for NOS1
        Phagosomal maturation (early endosomal stage)
    Nitric oxide stimulates guanylate cyclase

    2 PharmGKB Pathways for NOS1
        Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics
    Doxorubicin Pathway, Pharmacokinetics

    Selected Kegg Pathways  (Kegg details for NOS1) (see all 9):
        Arginine and proline metabolism
    Metabolic pathways
    Calcium signaling pathway
    Phagosome
    Circadian entrainment


    NOS1 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including NOS1: 
              Nitric Oxide Signaling Pathway in human mouse rat
              Synaptic Plasticity in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for NOS1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NOS1 (P294751, 2, 3 ENSP000003207584) via UniProtKB, MINT, STRING, and/or I2D (see all 89)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VAC14Q08AM61, 2, 3, ENSP000002617764EBI-7164065,EBI-2107455 MINT-3999924 MINT-3999953 MINT-3999982 MINT-3999902 MINT-3999876 I2D: score=3 STRING: ENSP00000261776
    CALM1P621583, ENSP000003494674I2D: score=1 STRING: ENSP00000349467
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    ADRA1AP353483, ENSP000003699604I2D: score=2 STRING: ENSP00000369960
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 30):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEP16276418
    GO:0002028regulation of sodium ion transport ----
    GO:0006527arginine catabolic process IC7545544
    GO:0006809nitric oxide biosynthetic process ISS7545544
    GO:0006941striated muscle contraction IEA--

    NOS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Enzo Life Sciences drugs & compounds for NOS1
      Browse compounds at ApexBio 

    Compounds for NOS1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    3-Bromo-7-nitroindazoleSelective nNOS inhibitor[74209-34-0]
    Nomega-Propyl-L-arginine hydrochlorideHighly selective inhibitor of nNOS[137361-05-8]
    ARL 17477 dihydrochlorideSelective nNOS inhibitor[180983-17-9]

    Selected HMDB Compounds for NOS1 (see all 14)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Dihydrobiopterin(S-(R*,S*))-2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-4(1H)-Pteridinone (see all 15)6779-87-916804678
    Tetrahydrobiopterin(1R,2S)-(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)-1,2-propandiol (see all 11)17528-72-216216381
    CalciumCa (see all 2)7440-70-2--
    Citrulline(2S)-2-amino-5-(carbamoylamino)pentanoic acid (see all 55)372-75-8--
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    Flavin MononucleotideFMN (see all 19)146-17-8--
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    L-Arginine(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)74-79-3--
    N-(o)-HydroxyarginineN-(G)-Hydroxyarginine (see all 2)----
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--

    Selected DrugBank Compounds for NOS1 (see all 26)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Citrulline2-Amino-5-uredovaleric acid (see all 8)372-75-8target--10681601 10502685 10962148 10945985 10799481
    (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin-- --target--17139284 17016423 10592235
    2'-Monophosphoadenosine 5'-Diphosphoribose-- --target--17139284 17016423 10592235
    3-Bromo-7-Nitroindazole-- --target--17139284 17016423 10592235
    5-N-Allyl-Arginine-- --target--17139284 17016423 10592235
    Alpha-D-Mannose-- 3458-28-4target--17139284 17016423 10592235
    Flavin-Adenine Dinucleotide-- 146-14-5target--17139284 17016423 10592235
    Heme-- --target--17139284 17016423 10592235
    L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide-- --target--17139284 17016423 10592235
    L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide-- --target--17139284 17016423 10592235

    2 IUPHAR Ligands for NOS1 (Neuronal NOS)    About this table
    LigandTypeActionAffinityPubmed IDs
    3-bromo-7NI
    InhibitorInhibition6.1 - 6.57544863
    7NI
    InhibitorInhibition5.37693279

    Selected Novoseek inferred chemical compound relationships for NOS1 gene (see all 127)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nitric oxide 94.2 3522 18580182 (7), 16581191 (7), 17320763 (6), 7524095 (6) (see all 99)
    tetrahydrobiopterin 92.1 193 16216381 (6), 7691806 (5), 9858648 (4), 7514193 (2) (see all 99)
    citrulline 87.1 144 12586539 (4), 14725962 (3), 17110176 (3), 8962079 (2) (see all 91)
    7-nitroindazole 85.1 167 7542758 (3), 11448483 (3), 12322787 (3), 15138761 (2) (see all 70)
    arginine 84.3 472 7519607 (9), 14602725 (5), 15007014 (5), 8955074 (4) (see all 99)
    n(g)-hydroxy-l-arginine 81.7 27 9398165 (4), 19128180 (3), 11481035 (2), 9735327 (1) (see all 12)
    nadph 81.2 265 10847600 (6), 7528212 (5), 12429187 (4), 8690302 (4) (see all 99)
    dihydrobiopterin 78.6 14 8626754 (3), 16804678 (1), 15476407 (1), 16118486 (1) (see all 6)
    peroxynitrite 75.9 47 8839053 (4), 11085318 (3), 12208472 (2), 9398256 (2) (see all 28)
    n-omega-propyl-l-arginine 75 21 15160393 (2), 16423462 (1), 17572695 (1), 19019012 (1) (see all 8)



    NOS1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NOS1 gene (4 alternative transcripts): 
    NM_000620.4  NM_001204213.1  NM_001204214.1  NM_001204218.1  

    Unigene Cluster for NOS1:

    Nitric oxide synthase 1 (neuronal)
    Hs.654410  [show with all ESTs]
    Unigene Representative Sequence: NM_001204218
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317775(uc021ren.1 uc021reo.1 uc001twn.2 uc001twm.2)
    ENST00000338101 ENST00000549189 ENST00000477584 ENST00000344089
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NOS1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NOS1 (see all 74):
    hsa-miR-4254 hsa-miR-146a hsa-miR-15a hsa-miR-938 hsa-miR-371-5p hsa-miR-502-3p hsa-miR-149 hsa-miR-3116
    SwitchGear 3'UTR luciferase reporter plasmidNOS1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NOS1
    Predesigned siRNA for gene silencing in human, mouse, rat NOS1
    Clone
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    OriGene clones in human, mouse for NOS1 (see all 7)
    OriGene ORF clones in mouse, rat for NOS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): NOS1 (NM_000620)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOS1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NOS1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOS1
      QuantiTect SYBR Green Assays in human, mouse, rat NOS1
      QuantiFast Probe-based Assays in human, mouse, rat NOS1

    Additional mRNA sequence: 

    AF446135.1 AJ004918.1 AK294435.1 AK307481.1 BC010126.2 BC033208.1 D16408.1 EU753241.1 
    L02881.1 U17327.1 U31466.1 

    5 DOTS entries:

    DT.209591  DT.430999  DT.40118528  DT.121200078  DT.87046327 

    Selected AceView cDNA sequences (see all 49):

    NM_000620 AI793292 BX115063 BC010126 AA935529 BE744153 AI914145 BX105805 
    AI299150 U17327 AJ004918 AF446131 AI791677 BE669690 BE297602 BF433556 
    AF446135 U31466 D16408 BC033208 AI302351 BE741353 BE326294 L02881 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NOS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGGCTTCT
    NOS1 Expression
    About this image


    NOS1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 5 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Adult Endothelial Cells Blood Brain Barrier
             Midbrain tegmentum
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Gut Tube (Gastrointestinal Tract)
             Midgut
    NOS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NOS1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654410

    UniProtKB/Swiss-Prot: NOS1_HUMAN, P29475
    Tissue specificity: Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis,
    lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3
    is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in
    the brain, but not in the heart and adrenal gland

        Pathway & Disease-focused RT2 Profiler PCR Arrays including NOS1: 
              Nitric Oxide Signaling Pathway in human mouse rat
              Synaptic Plasticity in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NOS1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOS1
    QuantiTect SYBR Green Assays in human, mouse, rat NOS1
    QuantiFast Probe-based Assays in human, mouse, rat NOS1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NOS1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nos11 , 5 nitric oxide synthase 1, neuronal1, 5 87.05(n)1
    94.05(a)1
      5 (57.29 cM)5
    181251  NM_008712.21  NP_032738.11 
     1177810325 
    chicken
    (Gallus gallus)
    Aves NOS11 nitric oxide synthase 1 (neuronal) 80.04(n)
    84.36(a)
      427721  XM_004934480.1  XP_004934537.1 
    lizard
    (Anolis carolinensis)
    Reptilia NOS16
    nitric oxide synthase 1 (neuronal)
    81(a)
    1 ↔ 1
    LGb(2413952-2463375)
    African clawed frog
    (Xenopus laevis)
    Amphibia nos1-A2 neuronal nitric oxide synthase 1 76.45(n)    AF053935.2 
    zebrafish
    (Danio rerio)
    Actinopterygii nos12 nitric oxide synthase 1 (neuronal) 74.9(n)   60658  AY211528.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nos1 , 3 imaginal disc development calmodulin
    binding3
    Nitric oxide synthase1
    49(a)3
    56.44(n)1
    51.37(a)1
      2 32B13
    344951  NM_078817.31  NP_523541.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NCP16
    NADP-cytochrome P450 reductase; involved in ergost...
    25(a)
    1 → many
    VIII(190543-192618) YHR042W


    ENSEMBL Gene Tree for NOS1 (if available)
    TreeFam Gene Tree for NOS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NOS1 gene
    NOS32  POR2  NOS22  MTRR2  
    2 SIMAP similar genes for NOS1 using alignment to 5 protein entries:     NOS1_HUMAN (see all proteins):
    NOS3    NOS2

    NOS1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NOS1 (see all 3617)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1495514001,2
    --114654634(+) TTCCCC/TTCCCC 4 -- ds50010--------
    rs779348951,2
    C,F--114654681(+) TCTTTT/CCCTCT 4 -- ds50011Minor allele frequency- C:0.16EA 120
    rs732060861,2
    C,F--114654699(+) CTTTCC/TCTCCT 4 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1878691161,2
    --114654871(+) CCTCCC/TCTCTC 4 -- ds50010--------
    rs560557391,2
    C--114655039(+) TCTGGA/GGCACC 4 -- ds50010--------
    rs714446101,2
    C--114655364(+) ACAGC-/GT/GTG
    TGTGTGTGT
    GTGTG
    8 -- ut31 cds11NA 2
    rs668864451,2
    C--114655365(+) CAGCG-/GT/GTGTG
    TGTGTGTGTGT
    TGTGT
    8 -- ut310--------
    rs587149991,2
    C--114655395(+) GTGTG-/TGT/TGTGT/TGTGTGTGT
    GTGT
    /TGTGTGTGTGTGTGTG
    GTGAG
    16 -- cds1 ut310--------
    rs1918675061,2
    --114655723(+) ACAGGG/TTCTCA 4 -- ut310--------
    rs73081501,2
    C,F,A--114655764(+) CATCTC/TGGCTC 4 -- ut312Minor allele frequency- T:0.50WA CSA 4

    HapMap Linkage Disequilibrium report for NOS1 (117645947 - 117889975 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for NOS1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746436CNV Deletion23290073
    esv2746435CNV Deletion23290073
    nsv901CNV Insertion18451855
    nsv509478CNV Insertion20534489
    nsv832526CNV Loss17160897
    nsv53465CNV Loss16902084
    nsv510592CNV Loss20534489

    Human Gene Mutation Database (HGMD): NOS1
    Locus Specific Mutation Databases (LSDB): NOS1

    1 Site Specific Mutation Identification with PCR Assay for NOS1:
    Cosmic IdAA Change
    110337p.S771L
    SeqTarget long-range PCR primers for resequencing NOS1
    DNA2.0 Custom Variant and Variant Library Synthesis for NOS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 163731    OMIM disorders: --

    Selected diseases for NOS1 (see all 159):    
    About MalaCards
    pyloric stenosis    factitious disorder    spermatogenic failure 12    intestinal perforation
    sepiapterin reductase deficiency    hypertrophic pyloric stenosis    mood disorder    impotence
    gastroparesis    schizoaffective disorder    cerebral hypoxia    achalasia
    childhood-onset schizophrenia    psychotic disorder    hyperphenylalaninemia    morphine dependence
    tetrahydrobiopterin deficiency    brain injury    gastroschisis    brain ischemia

    1 disease from the University of Copenhagen DISEASES database for NOS1:
    Vascular disease

    NOS1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Selected Novoseek inferred disease relationships for NOS1 gene (see all 92)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pyloric stenosis 59 21 11283889 (3), 14757827 (2), 9354728 (1), 15361336 (1) (see all 14)
    diabetic gastroparesis 54 6 12768383 (1), 17161551 (1), 17160518 (1), 20185690 (1) (see all 5)
    muscular dystrophy duchenne 51.2 20 17313973 (2), 11745948 (2), 9536265 (1), 9398448 (1) (see all 16)
    pyloric stenosis, infantile 50.5 4 8571963 (2)
    neurodegenerative diseases 49.3 23 7523410 (2), 19268602 (1), 20337441 (1), 9847056 (1) (see all 13)
    erectile dysfunction 47.9 4 9284206 (1), 9631946 (1), 7588327 (1), 8562693 (1)
    schizophrenia 45.5 85 19513863 (6), 12140778 (4), 19200422 (4), 18544180 (3) (see all 46)
    brain ischemia 43.5 3 16141535 (1), 10320673 (1)
    schizoaffective disorder 42.7 12 9988837 (1), 17665305 (1), 8483645 (1), 17267179 (1) (see all 11)
    neurodegeneration 41.9 15 15579064 (1), 16095570 (1), 16179512 (1), 18805011 (1) (see all 11)

    Genetic Association Database (GAD): NOS1
    Human Genome Epidemiology (HuGE) Navigator: NOS1 (103 documents)

    Export disorders for NOS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOS1 gene, integrated from 10 sources (see all 1622) (see top 10):
    (articles sorted by number of sources associating them with NOS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic association analysis of functional polymorphisms in neuronal nitric oxide synthase 1 gene (NOS1) and mood disorders and fluvoxamine response in major depressive disorder in the Japanese population. (PubMed id 20016223)1, 4, 9 Okumura T....Iwata N. (Neuropsychobiology 2010)
    2. Nasal nitric oxide levels in cystic fibrosis patients are associated with a neuronal NO synthase (NOS1) gene polymorphism. (PubMed id 11890749)1, 4, 9 Grasemann H....Ratjen F. (Nitric Oxide 2002)
    3. Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome. (PubMed id 18058820)1, 4, 9 Winkelmann J....MA1ller-Myhsok B. (Mov. Disord. 2008)
    4. Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis. (PubMed id 14757827)1, 4, 9 Saur D....Allescher H.D. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    5. Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines. (PubMed id 7515942)1, 2, 9 Fujisawa H....Esumi H. (J. Neurochem. 1994)
    6. Association between achalasia and nitric oxide synthase gene polymorphisms. (PubMed id 16848803)1, 4, 9 Mearin F....Lanas A. (Am. J. Gastroenterol. 2006)
    7. Effects of sex and of gene variants in constitutive nitric oxide synthases on exhaled nitric oxide. (PubMed id 12531780)1, 4, 9 Grasemann H....Ratjen F. (Am. J. Respir. Crit. Care Med. 2003)
    8. Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia. (PubMed id 12140778)1, 4, 9 Shinkai T....Nakamura J. (Mol. Psychiatry 2002)
    9. Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects. (PubMed id 19805695)1, 4, 9 Donohoe G....Corvin A. (Arch. Gen. Psychiatry 2009)
    10. Environmental exposures, nitric oxide synthase genes, and exhaled nitric oxide in asthmatic children. (PubMed id 19603529)1, 4, 9 Spanier A.J....Lanphear B.P. (Pediatr. Pulmonol. 2009)
    11. Evidence for association between the 5' flank of the NOS1 gene and schizophrenia in the Chinese population. (PubMed id 18544180)1, 4, 9 Tang W....Shi Y. (Int. J. Neuropsychopharmacol. 2008)
    12. Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study. (PubMed id 17328085)1, 4, 9 Li C....Wei Q. (Cancer 2007)
    13. Nitric oxide synthase 1 as a potential modifier gene of decline in lung function in patients with cystic fibrosis. (PubMed id 14760158)1, 4, 9 Texereau J....Dinh-Xuan A.T. (Thorax 2004)
    14. Exhaled nitric oxide in patients with asthma: association with NOS1 genotype. (PubMed id 11112111)1, 4, 9 Wechsler M.E....Drazen J.M. (Am. J. Respir. Crit. Care Med. 2000)
    15. Localization of brain nitric oxide synthase (NOS) to human chromosome 12. (PubMed id 1385308)1, 3, 9 Kishimoto J....Xu W. (Genomics 1992)
    16. The effect of a promoter polymorphism on the transcription of nitric oxide synthase 1 and its relevance to Parkinson's disease. (PubMed id 19326438)1, 4, 9 Rife T....Kurth J. (J. Neurosci. Res. 2009)
    17. Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms. (PubMed id 17351927)1, 4, 9 Duckworth L....Lima J.J. (Pediatr. Pulmonol. 2007)
    18. Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children. (PubMed id 16238787)1, 4, 9 Leung T.F....Wong G.W. (Clin. Exp. Allergy 2005)
    19. [Polymorphic markers of the NO synthase genes and genetic predisposition to diabetic polyneuropathy in patients with type 1 diabetes mellitus]. (PubMed id 15856945)1, 4, 9 Zotova E.V....Nosikov V.V. (Mol. Biol. (Mosk.) 2005)
    20. No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer Disease. (PubMed id 12210288)1, 4, 9 Liou Y.J....Tsai S.J. (Am. J. Med. Genet. 2002)
    21. Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes. (PubMed id 11668616)1, 4, 9 Immervoll T....Wjst M. (Hum. Mutat. 2001)
    22. No association between a promoter NOS1 polymorphism (rs41279104) and Infantile Hypertrophic Pyloric Stenosis. (PubMed id 19851341)1, 4, 9 Lagerstedt-Robinson K....NordenskjAPld A. (J. Hum. Genet. 2009)
    23. Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women. (PubMed id 19372141)1, 4, 9 Lee J.Y....Kang D. (Carcinogenesis 2009)
    24. Association of a NOS1 promoter repeat with Alzheimer's disease. (PubMed id 17418914)1, 4, 9 Galimberti D....Reif A. (Neurobiol. Aging 2008)
    25. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. (PubMed id 17690329)1, 4, 9 Demeo D.L....Silverman E.K. (Am. J. Respir. Cell Mol. Biol. 2008)
    26. No association between Parkinson's disease and three polymorphisms in the eNOS, nNOS, and iNOS genes. (PubMed id 17174475)1, 4, 9 Huerta C....Alvarez V. (Neurosci. Lett. 2007)
    27. A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function. (PubMed id 16389274)1, 4, 9 Reif A....Lesch K.P. (Mol. Psychiatry 2006)
    28. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. (PubMed id 16380905)1, 4, 9 Fallin M.D....Pulver A.E. (Am. J. Hum. Genet. 2005)
    29. Neuronal nitric oxide synthase gene polymorphism and IgE-mediated allergy in the Central European population. (PubMed id 15080837)1, 4, 9 HollA! L.I....VA!cha J. (Allergy 2004)
    30. Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia. (PubMed id 15075442)1, 4, 9 Shinkai T....Nakamura J. (Neuromolecular Med. 2004)
    31. Association analysis for neuronal nitric oxide synthase gene polymorphism with major depression and fluoxetine response. (PubMed id 12759556)1, 4, 9 Yu Y.W....Tsai S.J. (Neuropsychobiology 2003)
    32. Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study. (PubMed id 12490535)1, 4, 9 Levecque C....Chartier-Harlin M.C. (Hum. Mol. Genet. 2003)
    33. NOS1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children. (PubMed id 12911502)1, 4, 9 Ali M....Franklin P. (Pediatr Allergy Immunol 2003)
    34. Neuronal isoform of nitric oxide synthase is expressed at low levels in human retina. (PubMed id 8879752)1, 2, 9 Park C.-S.... Krishna G. (Cell. Mol. Neurobiol. 1996)
    35. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. (PubMed id 21041608)1, 4 van Winkel R. (Arch. Gen. Psychiatry 2011)
    36. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (Hum. Immunol. 2010)
    37. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    38. Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD. (PubMed id 20581851)1, 4 Tu Y.C....Wang D.W. (Acta Pharmacol. Sin. 2010)
    39. A putative cis-acting polymorphism in the NOS1 gene is associated with schizophrenia and NOS1 immunoreactivity in the postmortem brain. (PubMed id 20605417)1, 4 Cui H....Hishimoto A. (Schizophr. Res. 2010)
    40. Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (Vaccine 2010)
    41. EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity. (PubMed id 20028935)1, 4 Darrah R....Drumm M.L. (Physiol. Genomics 2010)
    42. Lack of association between nNOS -84G&gt;A polymorphism and risk of infantile hypertrophic pyloric stenosis in a Chinese population. (PubMed id 20385275)1, 4 Miao X....Tam P.K. (J. Pediatr. Surg. 2010)
    43. Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. (PubMed id 19844207)1, 4 Riley B....Kendler K.S. (Mol. Psychiatry 2010)
    44. A gradient of NOS1 overproduction alleles in European and Mediterranean populations. (PubMed id 20818978)1, 4 Piras I....Varesi L. (Genet Test Mol Biomarkers 2010)
    45. A common polymorphism in the 3'-UTR of the NOS1 gene was associated with completed suicides in Japanese male population. (PubMed id 20470850)1, 4 Cui H....Hishimoto A. (amp 2010)
    46. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    47. Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. (PubMed id 20921115)1, 4 Nicodemus K.K....Weinberger D.R. (Arch. Gen. Psychiatry 2010)
    48. Replication of genetic association studies in asthma and related phenotypes. (PubMed id 20395963)1, 4 Undarmaa S....Suzuki Y. (J. Hum. Genet. 2010)
    49. Association of a functional variant of neuronal nitric oxide synthase gene with self-reported impulsiveness, venturesomeness and empathy in male offenders. (PubMed id 19997858)1, 4 Retz W....RAPsler M. (J Neural Transm 2010)
    50. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
    51. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (amp 2010)
    52. The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal lobar degeneration. (PubMed id 19087148)1, 4 Venturelli E....Galimberti D. (Eur. J. Neurol. 2009)
    53. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
    54. Association of five single nucleotide polymorphism loci with asthma in children of Chinese Han nationality. (PubMed id 19657898)1, 4 Lv J....Bao Y. (J Asthma 2009)
    55. High frequencies of short alleles of NOS1 (CA)n polymorphism in beta(0)39 carriers from Corsica Island (France). (PubMed id 19103196)1, 4 Piras I.S....Varesi L. (Exp. Mol. Pathol. 2009)
    56. Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors. (PubMed id 19505917)1, 4 Bhatti P....Rajaraman P. (amp 2009)
    57. Microarray analysis of multiple candidate genes and associated plasma proteins for nephropathy secondary to type 2 diabetes among Chinese individuals. (PubMed id 19415232)1, 4 Lim S.C....Chia K.S. (Diabetologia 2009)
    58. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)1, 4 Yosifova A....Nakamura Y. (J Affect Disord 2009)
    59. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (Hum. Genet. 2009)
    60. An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). (PubMed id 19161160)1, 4 Franke B....Blom H.J. (Birth Defects Res. Part A Clin. Mol. Teratol. 2009)
    61. Nitric oxide synthase gene polymorphisms in children with minimal change nephrotic syndrome. (PubMed id 19371282)1, 4 Alasehirli B....Kont A. (Pediatr Int 2009)
    62. Family-based association study between NOS-I and -IIA polymorphisms and autism spectrum disorders in Korean trios. (PubMed id 18563708)1, 4 Kim H.W....Yoo H.J. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    63. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    64. Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma. (PubMed id 19423521)1, 4 Han X....Zhang Y. (amp 2009)
    65. Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans. (PubMed id 19124687)1, 4 Reif A....Lesch K.P. (Arch. Gen. Psychiatry 2009)
    66. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    67. Genetic profiling of genes from the oxidative stress pathway among North and South Indians. (PubMed id 18720901)1, 4 Tiwari A.K....Thelma B.K. (Hum. Biol. 2008)
    68. Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. (PubMed id 18606955)1, 4 Schumann G....Mann K. (Arch. Gen. Psychiatry 2008)
    69. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PubMed id 18821565)1, 4 Lasky-Su J....Faraone S.V. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    70. NOS-I and -III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits. (PubMed id 17579350)1, 4 Rujescu D....Serretti A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    71. Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation. (PubMed id 17448763)1, 4 Garcia-Barcelo M....Tam P.K. (J. Pediatr. Surg. 2007)
    72. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    73. Nitric oxide synthase gene polymorphisms in children with primary nocturnal enuresis: a preliminary study. (PubMed id 17365914)1, 4 Balat A....Gungor M. (Ren Fail 2007)
    74. A NOS1 gene polymorphism associated with asthma and specific immunoglobulin E response to mite allergens in a Colombian population. (PubMed id 17536218)1, 4 MartA-nez B....Caraballo L. (Int. Arch. Allergy Immunol. 2007)
    75. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (J. Infect. Dis. 2007)
    76. A population genomics overview of the neuronal nitric oxide synthase (nNOS) gene and its relationship to migraine susceptibility. (PubMed id 16191396)1, 4 Johnson M.P....Griffiths L.R. (Cell. Mol. Biol. (Noisy-le-grand) 2005)
    77. Family-based case-control study of cigarette smoking and Parkinson disease. (PubMed id 15699372)1, 4 Scott W.K....Vance J.M. (Neurology 2005)
    78. Genetic analysis of 22 candidate genes for hypertension in the Japanese population. (PubMed id 15167446)1, 4 Iwai N....Shioji K. (J. Hypertens. 2004)
    79. Investigation of a neuronal nitric oxide synthase gene (NOS1) polymorphism in a multiple sclerosis population. (PubMed id 14759629)1, 4 Tajouri L....Griffiths L.R. (J. Neurol. Sci. 2004)
    80. Association analysis of a neural nitric oxide synthase gene polymorphism and antipsychotics-induced tardive dyskinesia in Chinese schizophrenic patients. (PubMed id 15088155)1, 4 Wang Y.C....Chen J.Y. (J Neural Transm 2004)
    81. Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease. (PubMed id 12782337)1, 4 Styczynska M....Barcikowska M. (Neurosci. Lett. 2003)
    82. Polymorphisms of the IL-1beta and IL-1beta-inducible genes in ulcerative colitis. (PubMed id 12572877)1, 4 Nohara H....Hinoda Y. (J. Gastroenterol. 2002)
    83. Analysis of nitric oxide synthase genes in cluster headache. (PubMed id 12421162)1, 4 SjAPstrand C....Hillert J. (Cephalalgia 2002)
    84. No linkage or association of the nitric oxide synthase genes to multiple sclerosis. (PubMed id 11525805)1, 4 Modin H....Hillert J. (J. Neuroimmunol. 2001)
    85. Isolation and characterization of a novel, human neuronal nitric oxide synthase cDNA. (PubMed id 9791007)1, 2 Larsson B. and Phillips S.C. (Biochem. Biophys. Res. Commun. 1998)
    86. A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase. (PubMed id 9111048)1, 2 Wang Y.... Marsden P.A. (J. Biol. Chem. 1997)
    87. Structural organization of the human neuronal nitric oxide synthase gene (NOS1). (PubMed id 7528745)1, 2 Hall A.V.... Marsden P.A. (J. Biol. Chem. 1994)
    88. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. (PubMed id 7682706)1, 3 Geller D.A....Billiar T.R. (Proc. Natl. Acad. Sci. U.S.A. 1993)
    89. Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. (PubMed id 7678401)1, 2 Nakane M.... Murad F. (FEBS Lett. 1993)
    90. Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase. (PubMed id 15466472)1, 9 Peng H.M.... Osawa Y. (J. Biol. Chem. 2004)
    91. Neuronal nitric oxide synthase expression in glial tumors: correlation with malignancy and tumor proliferation. (PubMed id 18671896)1, 9 Tanriover N....Akar Z. (Neurol. Res. 2008)
    92. The neuronal nitric oxide synthase is upregulated in mouse skin repair and in response to epidermal growth factor in human HaCaT keratinocytes. (PubMed id 15191553)1, 9 Boissel J.P....Frank S. (J. Invest. Dermatol. 2004)
    93. Interaction of neuronal nitric-oxide synthase and phosphofructokinase-M. (PubMed id 10187848)1, 9 Firestein B.L. and Bredt D.S. (J. Biol. Chem. 1999)
    94. No association between polymorphisms of neuronal oxide synthase 1 gene (NOS1) and schizophrenia in a Japanese population. (PubMed id 19513863)1, 9 Okumura T....Iwata N. (Neuromolecular Med. 2009)
    95. Dynamic cycling with Hsp90 stabilizes neuronal nitric oxide synthase through calmodulin-dependent inhibition of ubiquitination. (PubMed id 19642705)1, 9 Peng H.M....Osawa Y. (Biochemistry 2009)
    96. Retinoic acid-induced nNOS expression depends on a novel PI3K/Akt/DAX1 pathway in human TGW-nu-I neuroblastoma cells. (PubMed id 19726747)1, 9 Nagl F....Saur D. (Am. J. Physiol., Cell Physiol. 2009)
    97. Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase. (PubMed id 16216381)6, 9 Kamada Y....Osawa Y. (Brain Res. Mol. Brain Res. 2005)
    98. Changes in the dimeric state of neuronal nitric oxide synthase affect the kinetics of secretagogue-induced insulin response. (PubMed id 15161750)1, 9 Lajoix A.D....Gross R. (Diabetes 2004)
    99. Expression of NOS1 and soluble guanylyl cyclase by human kidney epithelial cells: morphological evidence for an autocrine/paracrine action of nitric oxide. (PubMed id 12787407)1, 9 Jarry A....Vallette G. (Kidney Int. 2003)
    100. An alternative promoter of the human neuronal nitric oxide synthase gene is expressed specifically in Leydig cells. (PubMed id 11786430)1, 9 Wang Y....Marsden P.A. (Am. J. Pathol. 2002)
    101. Sepsis is associated with reciprocal expressional modifications of constitutive nitric oxide synthase (NOS) in human skeletal muscle: down-regulation of NOS1 and up-regulation of NOS3. (PubMed id 11546971)1, 9 Lanone S....Boczkowski J. (Crit. Care Med. 2001)
    102. Interaction of endothelial and neuronal nitric-oxide synthases with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation. (PubMed id 10681501)1, 9 Golser R....Mayer B. (J. Biol. Chem. 2000)
    103. Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin-dependent protein kinase IIalpha through Ser847 phosphorylation in NG108-15 neuronal cells. (PubMed id 10874031)1, 9 Komeima K....Watanabe Y. (J. Biol. Chem. 2000)
    104. Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo. (PubMed id 9880522)1, 9 Bender A.T....Osawa Y. (J. Biol. Chem. 1999)
    105. ChAT and NOS in human myenteric neurons: co-existence and co-absence. (PubMed id 19711100)1, 9 Beck M....Brehmer A. (Cell Tissue Res. 2009)
    106. Nitric oxide inhibition of ERK1/2 activity in cells expressing neuronal nitric-oxide synthase. (PubMed id 14602725)1, 9 Raines K.W....Shapiro P. (J. Biol. Chem. 2004)
    107. Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains. (PubMed id 12777376)1, 9 Guan Z.W....Iyanagi T. (J. Biol. Chem. 2003)
    108. Association of functional polymorphisms in NOS1 and NOS3 with loudness dependence of auditory evoked potentials. (PubMed id 18257968)1, 9 Kawohl W....Juckel G. (Int. J. Neuropsychopharmacol. 2008)
    109. Expression of nitric oxide synthases in keratinocytes after UVB irradiation. (PubMed id 14615895)1, 9 Chang H.R....Yu H.S. (Arch. Dermatol. Res. 2003)
    110. A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma. (PubMed id 10833424)4, 9 Grasemann H....Drazen J.M. (Biochem. Biophys. Res. Commun. 2000)
    111. Neuronal nitric oxide synthase and human vascular regulation. (PubMed id 20447567)1, 9 Melikian N....Shah A.M. (Trends Cardiovasc. Med. 2009)
    112. Expression, localization, and regulation of NOS in human mast cell lines: effects on leukotriene production. (PubMed id 15044250)1, 9 Gilchrist M....Befus A.D. (Blood 2004)
    113. Immunocytochemical distribution of nitric oxide synthase in the human seminal vesicle: a light and electron microscopical study. (PubMed id 12802542)1, 9 Uckert S....Machtens S. (Urol. Res. 2003)
    114. Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase. Implications for mechanism. (PubMed id 10945985)7, 9 Adak S....Stuehr D.J. (J. Biol. Chem. 2000)
    115. Variants of NOS1, NOS2, and NOS3 genes in asthmatics. (PubMed id 10673365)4, 9 Gao P.S....Hopkin J.M. (Biochem. Biophys. Res. Commun. 2000)
    116. Ultrastructural immunogold localization of nitric oxide synthase isoforms in rat and human eosinophils. (PubMed id 20232214)1, 9 Saluja R....Dikshit M. (Cell Tissue Res. 2010)
    117. Calpain-mediated activation of NO synthase in human neuroblastoma SK-N-BE cells. (PubMed id 19457105)1, 9 Averna M....Melloni E. (J. Neurochem. 2009)
    118. Neuronal nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo. (PubMed id 18048451)1, 9 Kellogg D.L....Wu Y. (J. Physiol. (Lond.) 2008)
    119. Possible role for nitric oxide dysregulation in critical illness myopathy. (PubMed id 17924542)1, 9 Capasso M....Uncini A. (amp 2008)
    120. Sarcolemma-localized nNOS is required to maintain activity after mild exercise. (PubMed id 18953332)1, 9 Kobayashi Y.M....Campbell K.P. (Nature 2008)
    121. Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease. (PubMed id 18663495)4, 9 Hancock D.B....Scott W.K. (Neurogenetics 2008)
    122. HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. (PubMed id 17360663)1, 9 Eugenin E.A....Berman J.W. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    123. Cutaneous neuronal nitric oxide is specifically decreased in postural tachycardia syndrome. (PubMed id 17660395)1, 9 Stewart J.M....Taneja I. (Am. J. Physiol. Heart Circ. Physiol. 2007)
    124. Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling. (PubMed id 17351066)1, 9 Han G....White R.E. (Am. J. Physiol. Heart Circ. Physiol. 2007)
    125. [Expression of cell adhesion molecule and nitric oxide synthase in nasal mucosa in allergic rhinitis]. (PubMed id 16780147)1, 9 Li Y....Zhang Q. (Lin Chuang Er Bi Yan Hou Ke Za Zhi 2006)
    126. Expression of nNOS and soluble guanylate cyclase in schizophrenic brain. (PubMed id 15094474)1, 9 Baba H....Emson P.C. (Neuroreport 2004)
    127. Electron transfer is activated by calmodulin in the flavin domain of human neuronal nitric oxide synthase. (PubMed id 12646269)1, 9 Guan Z.W. and Iyanagi T. (Arch. Biochem. Biophys. 2003)
    128. Cu2+ and Zn2+ inhibit nitric-oxide synthase through an interaction with the reductase domain. (PubMed id 10799481)7, 9 Perry J.M....Marletta M.A. (J. Biol. Chem. 2000)
    129. Formation of a native-like beta-hairpin finger structure of a peptide from the extended PDZ domain of neuronal nitric oxide synthase in aqueous solution. (PubMed id 10824095)1, 9 Wang P....Zhang M. (Eur. J. Biochem. 2000)
    130. Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase. (PubMed id 20043967)1, 9 Llansola M. and Felipo V. (Neurochem. Int. 2010)
    131. Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer. (PubMed id 19948738)1, 9 Guan Z.W....Stuehr D.J. (J. Biol. Chem. 2010)
    132. Differential responses of VIPergic and nitrergic neurons in paediatric patients with Crohn's disease. (PubMed id 17466601)1, 9 Boyer L....Jacobson K. (amp 2007)
    133. Fas (CD95) alters neuronal nitric oxide synthase expression to contribute in diabetic gastroparesis. (PubMed id 17161551)1, 9 Surendran S. (Med. Hypotheses 2007)
    134. Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein. (PubMed id 17029414)1, 9 Konas D.W....Stuehr D.J. (Biochemistry 2006)
    135. Structural studies of constitutive nitric oxide synthases with diatomic ligands bound. (PubMed id 16804678)6, 9 Li H....Poulos T.L. (J. Biol. Inorg. Chem. 2006)
    136. nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells. (PubMed id 15194886)1, 9 Wen Y....Simpkins J.W. (Neuroreport 2004)
    137. The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage. (PubMed id 15054088)7, 9 Fogli S....Breschi M.C. (FASEB J. 2004)
    138. Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure. (PubMed id 15033959)1, 9 Kavdia M. and Popel A.S. (J. Appl. Physiol. 2004)
    139. Post-synaptic density-95 promotes calcium/calmodulin-dependent protein kinase II-mediated Ser847 phosphorylation of neuronal nitric oxide synthase. (PubMed id 12630910)1, 9 Watanabe Y....Tokuda M. (Biochem. J. 2003)
    140. Transcription of different exons 1 of the human neuronal nitric oxide synthase gene is dynamically regulated in a cell- and stimulus-specific manner. (PubMed id 12715886)1, 9 Boissel J.P....FAPrstermann U. (Biol. Chem. 2003)
    141. Association analysis for the CA repeat polymorphism of the neuronal nitric oxide synthase (NOS1) gene and schizophrenia. (PubMed id 14623375)1, 9 Liou Y.J....Liao D.L. (Schizophr. Res. 2003)
    142. Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease. (PubMed id 12816735)1, 9 Barreiro E....Hussain S.N. (Am. J. Respir. Cell Mol. Biol. 2003)
    143. Assembly and activation of heme-deficient neuronal NO synthase with various porphyrins. (PubMed id 12237228)1, 9 Bender A.T....Osawa Y. (J. Inorg. Biochem. 2002)
    144. 5'-flanking region polymorphism of the neuronal nitric oxide synthase gene with Parkinson's disease in Taiwan. (PubMed id 11809160)4, 9 Lo H.S....Soong B.W. (J. Neurol. Sci. 2002)
    145. Ubiquitination of neuronal nitric-oxide synthase in vitro and in vivo. (PubMed id 10751385)1, 9 Bender A.T....Osawa Y. (J. Biol. Chem. 2000)
    146. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. (PubMed id 10221915)1, 9 Hillier B.J....Lim W.A. (Science 1999)
    147. PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. (PubMed id 10488080)1, 9 Christopherson K.S....Bredt D.S. (J. Biol. Chem. 1999)
    148. Nitric oxide synthase in cardiac sarcoplasmic reticulum. (PubMed id 9892689)1, 9 Xu K.Y....Becker L.C. (Proc. Natl. Acad. Sci. U.S.A. 1999)
    149. CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. (PubMed id 9459447)1, 9 Jaffrey S.R.... Snyder S.H. (Neuron 1998)
    150. Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. (PubMed id 7488039)1, 9 Chen P.F....Wu K.K. (Biochem. Biophys. Res. Commun. 1995)
    151. Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites. (PubMed id 1375933)1, 9 Bredt D.S....Snyder S.H. (J. Biol. Chem. 1992)
    152. Nuclear recruitment of neuronal nitric-oxide synthase by I+-syntrophin is crucial for the induction of mitochondrial biogenesis. (PubMed id 24235139)1 Aquilano K....Ciriolo M.R. (J. Biol. Chem. 2014)
    153. Nitric oxide synthase gene polymorphisms in functional dyspepsia. (PubMed id 24114042)1 Park J.M....Choi M.G. (Dig. Dis. Sci. 2014)
    154. Calmodulin activates neuronal nitric oxide synthase by enabling transitions between conformational states. (PubMed id 23159936)1 Salerno J.C....Ghosh D.K. (FEBS Lett. 2013)
    155. Inhibition of neuronal nitric oxide synthase activity promotes migration of human-induced pluripotent stem cell-derived neural stem cells toward cancer cells. (PubMed id 23406356)1 Chen C....Wang S. (J. Neurochem. 2013)
    156. Molecular clues about the dystrophin-neuronal nitric oxide synthase interaction: a theoretical approach. (PubMed id 24063785)1 Giudice E....Delalande O. (Biochemistry 2013)
    157. Charge-pairing interactions control the conformational setpoint and motions of the FMN domain in neuronal nitric oxide synthase. (PubMed id 23289611)1 Haque M.M....Stuehr D.J. (Biochem. J. 2013)
    158. Myocardial and lymphocytic expression of eNOS and nNOS before and after heart transplantation: relationship to clinical status. (PubMed id 23770231)1 Vicente D....D'Ocon P. (Life Sci. 2013)
    159. Lack of association between the C276T polymorphism of the neuronal nitric oxide synthase gene and migraine. (PubMed id 22937753)1 AlaA9ehirli B....Neyal M. (Int. J. Neurosci. 2013)
    160. Association analysis of nitric oxide synthases: NOS1, NOS2A and NOS3 genes, with multiple sclerosis. (PubMed id 23826716)1 AlFadhli S....Al Shubaili A. (Ann. Hum. Biol. 2013)
    161. Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. (PubMed id 23572278)1 Montesanto A....Rose G. (Biogerontology 2013)
    162. Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A. (PubMed id 23541953)1 Cheng J....Makielski J.C. (J. Mol. Cell. Cardiol. 2013)
    163. Dissecting the kinetics of the NADP(+)-FADH2 charge transfer complex and flavin semiquinones in neuronal nitric oxide synthase. (PubMed id 23567464)1 Li H....Poulos T.L. (J. Inorg. Biochem. 2013)
    164. AAT polymorphisms in intron 20 of NOS1 confer vulnerability to mite-induced allergic rhinitis in Chinese patients. (PubMed id 22448456)1 Yuan B.C....Lung F.W. (amp 2012)
    165. Association of a functional variant of the nitric oxide synthase 1 gene with personality, anxiety, and depressiveness. (PubMed id 23062293)1 Kurrikoff T....Harro J. (Dev. Psychopathol. 2012)
    166. NOS1 ex1f-VNTR polymorphism affects prefrontal oxygenation during response inhibition tasks. (PubMed id 21922604)1 Kopf J....Reif A. (Hum Brain Mapp 2012)
    167. The NOS1 variant rs6490121 is associated with variation in prefrontal function and grey matter density in healthy individuals. (PubMed id 22227051)1 Rose E.J....Donohoe G. (Neuroimage 2012)
    168. Structure and dynamics of calmodulin (CaM) bound to nitric oxide synthase peptides: effects of a phosphomimetic CaM mutation. (PubMed id 22486744)1 Piazza M....Guillemette J.G. (Biochemistry 2012)
    169. Immunohistochemical evidence for impaired nitric oxide signaling of the locus coeruleus in bipolar disorder. (PubMed id 22560594)1 Bielau H....Steiner J. (Brain Res. 2012)
    170. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. (PubMed id 22579290)1 Kwan K.Y....Sestan N. (Cell 2012)
    171. [Association study of NOS1 gene polymorphisms and schizophrenia]. (PubMed id 22875507)1 Wang J....Li T. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2012)
    172. Obesity, insulin resistance, and skeletal muscle nitric oxide synthase. (PubMed id 22797309)1 Kraus R.M....Hickner R.C. (J. Appl. Physiol. 2012)
    173. Expression of nitric oxide synthases in leukocytes in nasal polyps. (PubMed id 22374200)1 Yoshimura T....Befus A.D. (amp 2012)
    174. Neuronal nitric oxide synthase regulates endothelial inflammation. (PubMed id 22457368)1 Chakrabarti S....Davidge S.T. (J. Leukoc. Biol. 2012)
    175. Variable phenotype of del45-55 Becker patients correlated with nNOSI1 mislocalization and RYR1 hypernitrosylation. (PubMed id 22589245)1 Gentil C....PiActri-Rouxel F. (Hum. Mol. Genet. 2012)
    176. Exercise-induced angiogenesis correlates with the up-regulated expression of neuronal nitric oxide synthase (nNOS) in human skeletal muscle. (PubMed id 21505843)1 Huber-Abel F.A....Baum O. (Eur. J. Appl. Physiol. 2012)
    177. A NOS1 variant implicated in cognitive performance influences evoked neural responses during a high density EEG study of early visual perception. (PubMed id 21520349)1 O'Donoghue T....Donohoe G. (Hum Brain Mapp 2012)
    178. Development of the human corpus striatum and the presence of nNOS and 5-HT2A receptors. (PubMed id 22095614)1 Hu Z....Fang M. (Anat Rec (Hoboken) 2012)
    179. Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein. (PubMed id 23109339)1 Clapp K.M....Osawa Y. (J. Biol. Chem. 2012)
    180. Excitotoxic potential of the cyanotoxin I^-methyl-amino-L-alanine (BMAA) in primary human neurons. (PubMed id 22885173)1 Chiu A.S....Neilan B.A. (Toxicon 2012)
    181. Inflammation-related gene variants as risk factors for pancreatic cancer. (PubMed id 21467233)1 Reid-Lombardo K.M....Petersen G.M. (amp 2011)
    182. Cutaneous constitutive nitric oxide synthase activation in postural tachycardia syndrome with splanchnic hyperemia. (PubMed id 21642500)1 Stewart J.M....Medow M.S. (Am. J. Physiol. Heart Circ. Physiol. 2011)
    183. Functional variants in NOS1 and NOS2A are not associated with progressive hearing loss in MAcniA"re's disease in a European Caucasian population. (PubMed id 21612410)1 Gazquez I....Lopez-Nevot M.A. (DNA Cell Biol. 2011)
    184. A functional NOS1 promoter polymorphism interacts with adverse environment on functional and dysfunctional impulsivity. (PubMed id 20589495)1 Reif A....Harro J. (Psychopharmacology (Berl.) 2011)
    185. Characterization of a novel posttranslational modification in neuronal nitric oxide synthase by small ubiquitin-related modifier-1. (PubMed id 21545853)1 Watanabe M. and Itoh K. (Biochim. Biophys. Acta 2011)
    186. Association between inducible and neuronal nitric oxide synthase polymorphisms and recurrent depressive disorder. (PubMed id 20888049)1 GaA8ecki P....Szemraj J. (J Affect Disord 2011)
    187. Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells. (PubMed id 21722677)1 Saluja R....Dikshit M. (Biochim. Biophys. Acta 2011)
    188. NCAM1, TACR1 and NOS genes and temperament: a study on suicide attempters and controls. (PubMed id 21577011)1 Giegling I....Serretti A. (Neuropsychobiology 2011)
    189. The effects of L-NAME on neuronal NOS and SOD1 expression in the DRG-spinal cord network of axotomised Thy 1.2 eGFP mice. (PubMed id 22613021)1 Bradman M.J....Thippeswamy T. (Neuron Glia Biol. 2011)
    190. The effect of maternal and fetal I^2-adrenoceptor and nitric oxide synthase genotype on vasopressor requirement and fetal acid-base status during spinal anesthesia for cesarean delivery. (PubMed id 21613201)1 Landau R....Ngan Kee W.D. (Anesth. Analg. 2011)
    191. A functional promoter polymorphism of neuronal nitric oxide synthase moderates prefrontal functioning in schizophrenia. (PubMed id 21281558)1 Reif A....Ehlis A.C. (Int. J. Neuropsychopharmacol. 2011)
    192. NOS1 ex1f-VNTR polymorphism influences prefrontal brain oxygenation during a working memory task. (PubMed id 21620982)1 Kopf J....Reif A. (Neuroimage 2011)
    193. Genetic variations in nitric oxide synthase and arginase influence exhaled nitric oxide levels in children. (PubMed id 21039601)1 Salam M.T....Gilliland F.D. (Allergy 2011)
    194. Nitric oxide synthase genotype modulation of impulsivity and ventral striatal activity in adult ADHD patients and healthy comparison subjects. (PubMed id 21724667)1 Hoogman M....Franke B. (Am J Psychiatry 2011)
    195. Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. (PubMed id 21052031)1 Grilo A....SA!ez M.E. (Pharmacogenet. Genomics 2011)
    196. Genomic variants in the coding region of neuronal nitric oxide synthase (NOS1) in infantile hypertrophic pyloric stenosis. (PubMed id 22008325)1 Serra A....Fitze G. (J. Pediatr. Surg. 2011)
    197. mRNA expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and neuronal nitric oxide synthase genes in meningitis patients. (PubMed id 21204701)1 Oztuzcu S....Cakmak E.A. (Genet Test Mol Biomarkers 2011)
    198. Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis. (PubMed id 21679499)1 Zhang Y....Desrosiers M. (amp 2011)
    199. NOS inhibition synchronizes calcium oscillations in human adipose tissue-derived mesenchymal stem cells by increasing gap-junctional coupling. (PubMed id 21413022)1 Sauer H....Wartenberg M. (J. Cell. Physiol. 2011)
    200. Increased neuronal nitric oxide synthase dimerisation is involved in rat and human pancreatic beta cell hyperactivity in obesity. (PubMed id 21847584)1 Mezghenna K....Lajoix A.D. (Diabetologia 2011)
    201. Association of a functional NOS1 promoter repeat with Alzheimer's disease in the VITA cohort. (PubMed id 21098972)1 Reif A....Fischer P. (J. Alzheimers Dis. 2011)
    202. Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. (PubMed id 21056687)1 Baldelli S....Ciriolo M.R. (amp 2011)
    203. Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane. (PubMed id 22003386)1 Wehling-Henricks M. and Tidball J.G. (PLoS ONE 2011)
    204. Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders. (PubMed id 21403107)1 Finanger Hedderick E.L....Cohn R.D. (Neurology 2011)
    205. Characterization of a nitric oxide synthase from the plant kingdom: NO generation from the green alga Ostreococcus tauri is light irradiance and growth phase dependent. (PubMed id 21119059)1 Foresi N....Lamattina L. (Plant Cell 2010)
    206. Nitroxidergic innervation of human cerebral arteries. (PubMed id 20537599)1 Taktakishvili O.M....Talman W.T. (amp 2010)
    207. Neuronal NOS is dislocated during muscle atrophy in amyotrophic lateral sclerosis. (PubMed id 20435320)1 Suzuki N....Aoki M. (J. Neurol. Sci. 2010)
    208. Immunohistochemical evaluation of three nitric oxide synthase isoforms in human saphenous vein exposed to different degrees of distension pressures. (PubMed id 20060328)1 Viaro F....Evora P.R. (Cardiovasc. Pathol. 2010)
    209. The effects of NOS1 gene on asthma and total IgE levels in Taiwanese children, and the interactions with environmental factors. (PubMed id 20609134)1 Wang T.N....Ko Y.C. (Pediatr Allergy Immunol 2010)
    210. The effect of a functional NOS1 promoter polymorphism on impulsivity is moderated by platelet MAO activity. (PubMed id 20186396)1 Laas K....Harro J. (Psychopharmacology (Berl.) 2010)
    211. Differential roles of nitric oxide synthases in regulation of ultraviolet B light-induced apoptosis. (PubMed id 20547234)1 Liu W. and Wu S. (Nitric Oxide 2010)
    212. Nitric oxide synthase expression and functional response to nitric oxide are both important modulators of circulating angiogenic cell response to angiogenic stimuli. (PubMed id 20705916)1 Heiss C....Springer M.L. (Arterioscler. Thromb. Vasc. Biol. 2010)
    213. Is NOS1 a genetic link between RLS and ADHD? (PubMed id 19552920)1 Reif A. (J Psychiatr Res 2010)
    214. Genetic analysis of nitric oxide synthase 1 variants in schizophrenia and bipolar disorder. (PubMed id 20645313)1 Silberberg G....Navon R. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    215. Association of existing and new candidate genes for anxiety, depression and personality traits in older people. (PubMed id 20052609)1 Luciano M....Deary I.J. (Behav. Genet. 2010)
    216. C331A mutant of neuronal nitric-oxide synthase is labilized for Hsp70/CHIP (C terminus of HSC70-interacting protein)-dependent ubiquitination. (PubMed id 20729196)1 Clapp K.M....Osawa Y. (J. Biol. Chem. 2010)
    217. Neuronal nitric oxide synthase modulates maturation of human dendritic cells. (PubMed id 20421643)1 Adler H.S....Steinbrink K. (J. Immunol. 2010)
    218. Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion. (PubMed id 18971208)1 Kwon O....Ramesh G. (Am. J. Physiol. Renal Physiol. 2009)
    219. Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase. (PubMed id 19687346)1 Sankaralingam S....Davidge S.T. (Hypertension 2009)
    220. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (amp 2009)
    221. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    222. Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo. (PubMed id 19433760)1 Seddon M....Shah A.M. (Circulation 2009)
    223. [Expression of nNOS, Pax3 and Cx43 proteins in early developing posterior horn of embryonic and fetal human spinal cord]. (PubMed id 19726320)1 Zhang Y. and Liu X.H. (Nan Fang Yi Ke Da Xue Xue Bao 2009)
    224. Biochemistry of soluble guanylate cyclase. (PubMed id 19089323)1 Derbyshire E.R. and Marletta M.A. (Handb Exp Pharmacol 2009)
    225. Neuronal nitric oxide synthase C276T polymorphism increases the risk for frontotemporal lobar degeneration. (PubMed id 18042235)1 Venturelli E....Galimberti D. (Eur. J. Neurol. 2008)
    226. Constitutive nitric oxide synthase gene polymorphisms and house dust mite respiratory allergy in an Algerian patient group. (PubMed id 18086269)1 Djidjik R....Tamouza R. (Tissue Antigens 2008)
    227. Acute exercise does not cause sustained elevations in AMPK signaling or expression. (PubMed id 18614941)1 Lee-Young R.S....McConell G.K. (Med Sci Sports Exerc 2008)
    228. Influence of salt on subcellular localization of nitric oxide synthase activity and expression in the renal inner medulla. (PubMed id 17892502)1 Sullivan J.C....Pollock J.S. (amp 2008)
    229. Nitric oxide synthase isoforms and NF-kappaB activity in normal and osteoarthritic human chondrocytes: regulation by inducible nitric oxide. (PubMed id 18675932)1 Rosa S.C....Mendes A.F. (Nitric Oxide 2008)
    230. Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling. (PubMed id 18541744)1 Loyer X....Heymes C. (Circulation 2008)
    231. Metabolic profile and nitric oxide synthase expression of skeletal muscle fibers are altered in patients with type 1 diabetes. (PubMed id 18465682)1 Fritzsche K....Punkt K. (amp 2008)
    232. CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins. (PubMed id 18784277)1 Morishima Y....Lieberman A.P. (Hum. Mol. Genet. 2008)
    233. Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex. (PubMed id 18591664)1 Ueda K.... Makielski J.C. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    234. Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. (PubMed id 18391107)1 Seddon M.D....Shah A.M. (Circulation 2008)
    235. Different expression of NOS isoforms in early endothelial progenitor cells derived from peripheral and cord blood. (PubMed id 17492662)1 Muscari C....Guarnieri C. (J. Cell. Biochem. 2007)
    236. Activities of mitochondrial complexes correlate with nNOS amount in muscle from ALS patients. (PubMed id 17359361)1 SorarA^ G....Angelini C. (Neuropathol. Appl. Neurobiol. 2007)
    237. Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion. (PubMed id 18024942)1 Tsui J.C....Dashwood M.R. (Angiology 2007)
    238. Cardiomyocytes as effectors of nitric oxide signalling. (PubMed id 17568574)1 Seddon M....Casadei B. (Cardiovasc. Res. 2007)
    239. Skeletal muscle nNOS mu protein content is increased by exercise training in humans. (PubMed id 17459909)1 McConell G.K....Lee-Young R.S. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007)
    240. Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90. (PubMed id 17970747)1 Averna M....Melloni E. (FEBS J. 2007)
    241. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    242. Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity. (PubMed id 16569214)1 Raines K.W....Shapiro P. (Biochem. J. 2006)
    243. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) regulates endothelial nitric oxide synthase (eNOS) activity and its localization within the human vein endothelial cells (HUVEC) in culture. (PubMed id 16229016)1 Di Pietro R....Pandolfi A. (J. Cell. Biochem. 2006)
    244. Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new internal PDZ-recognition motif. (PubMed id 17161399)1 Lemaire J.F. and McPherson P.S. (FEBS Lett. 2006)
    245. Regulation of neuronal nitric-oxide synthase activity by somatostatin analogs following SST5 somatostatin receptor activation. (PubMed id 16690617)1 Cordelier P....Buscail L. (J. Biol. Chem. 2006)
    246. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (Nat Rev Drug Discov 2006)
    247. Pulmonary nitric oxide synthases and nitrotyrosine: findings during lung development and in chronic lung disease of prematurity. (PubMed id 16950998)1 Sheffield M....Truog W.E. (Pediatrics 2006)
    248. Drugs, their targets and the nature and number of drug targets. (PubMed id 17016423)7 Imming P....Meyer A. (Nat Rev Drug Discov 2006)
    249. Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter sequences. (PubMed id 16413742)1 Bros M....FAPrstermann U. (Genomics 2006)
    250. Nitric oxide synthase in retina and optic nerve head of rat with increased intraocular pressure and effect of timolol. (PubMed id 17027776)1 Vidal L....de Vargas I.P. (Brain Res. Bull. 2006)
    251. Association of neuronal nitric oxide synthase C276T polymorphism with Alzheimer's disease. (PubMed id 15765269)1 Galimberti D....Scarpini E. (J. Neurol. 2005)
    252. Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant. (PubMed id 16276418)1 Ward M.E....Marsden P.A. (J. Clin. Invest. 2005)
    253. 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. (PubMed id 14752097)1 Shang T....Kalyanaraman B. (J. Biol. Chem. 2004)
    254. Differential expression of nitric oxide synthases (NOS 1-3) in human skeletal muscle following exercise countermeasure during 12 weeks of bed rest. (PubMed id 15180967)1 Rudnick J....Blottner D. (FASEB J. 2004)
    255. Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. (PubMed id 15548660)1 Dreyer J.... Kuner R. (J. Neurosci. 2004)
    256. Calcium/calmodulin-dependent protein kinase I inhibits neuronal nitric-oxide synthase activity through serine 741 phosphorylation. (PubMed id 15251453)1 Song T....Watanabe Y. (FEBS Lett. 2004)
    257. Estrogen induces nitric oxide production via activation of constitutive nitric oxide synthases in human neuroblastoma cells. (PubMed id 15242984)1 Xia Y. and Krukoff T.L. (Endocrinology 2004)
    258. Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with the development of lupus nephritis. (PubMed id 15119548)1 Lee Y.H....Song G.G. (Lupus 2004)
    259. NIDD, a novel DHHC-containing protein, targets neuronal nitric-oxide synthase (nNOS) to the synaptic membrane through a PDZ-dependent interaction and regulates nNOS activity. (PubMed id 15105416)1 Saitoh F....Suzuki T. (J. Biol. Chem. 2004)
    260. Posttranscriptional regulation of neuronal nitric oxide synthase expression by IFN-gamma. (PubMed id 14980078)1 Chesler D.A....Reiss C.S. (amp 2004)
    261. Nitric oxide synthase 1 is partly compensating for nitric oxide synthase 3 deficiency in nitric oxide synthase 3 knock-out mice and is elevated in murine and human cirrhosis. (PubMed id 15287858)1 Biecker E....Reichen J. (Liver Int. 2004)
    262. Translational regulation of human neuronal nitric-oxide synthase by an alternatively spliced 5'-untranslated region leader exon. (PubMed id 12403769)1 Newton D.C....Marsden P.A. (J. Biol. Chem. 2003)
    263. Does endothelial nitric oxide synthase gene variation play a role in the occurrence of hypertension in pregnancy? (PubMed id 12908999)1 Grandone E....Margaglione M. (Hypertens Pregnancy 2003)
    264. Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in neurodegenerative processes. (PubMed id 14711010)1 Rotilio G....Ciriolo M.R. (IUBMB Life 2003)
    265. Inhibition of neural nitric oxide synthase attenuates the chloride secretory response to stroking in human jejunum. (PubMed id 12947326)1 King B.N....Kellum J.M. (Surgery 2003)
    266. Cellular compartmentalization of phosphorylated eIF2alpha and neuronal NOS in human temporal lobe epilepsy with hippocampal sclerosis. (PubMed id 12686399)1 Petrov T....Watson C. (J. Neurol. Sci. 2003)
    267. Interactions between inducible nitric oxide synthase and heme oxygenase-1 in glomerulonephritis. (PubMed id 11849436)1 Datta P.K....Lianos E.A. (Kidney Int. 2002)
    268. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    269. Neuronal nitric oxide synthase ligand and protein vibrations at the substrate binding site. A study by FTIR. (PubMed id 12081486)1 Ingledew W.J....Rich P.R. (Biochemistry 2002)
    270. Expression of nitric oxide synthase isoforms in human pregnant myometrium at term. (PubMed id 12445599)1 Bao S....Schreiber J. (J. Soc. Gynecol. Investig. 2002)
    271. Arginase in glomerulonephritis. (PubMed id 11849441)1 Waddington S.N. (Kidney Int. 2002)
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    273. Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors. (PubMed id 11960979)1 Saur D....Allescher H.D. (J. Biol. Chem. 2002)
    274. Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes. (PubMed id 12081996)1 Ashley E.A....Casadei B. (Circulation 2002)
    275. Interaction of neuronal nitric oxide synthase with alpha1-adrenergic receptor subtypes in transfected HEK-293 cells. (PubMed id 12184796)1 Pupo A.S. and Minneman K.P. (BMC Pharmacol. 2002)
    276. Further immunohistochemical evidence for impaired NO signaling in the hypothalamus of depressed patients. (PubMed id 12485841)1 Bernstein H.G....Baumann B. (Ann. N. Y. Acad. Sci. 2002)
    277. Association of neuronal nitric oxide synthase (nNOS) with alpha1-syntrophin at the sarcolemma. (PubMed id 11747091)1 Miyagoe-Suzuki Y. and Takeda S.I. (Microsc. Res. Tech. 2001)
    278. Binding of neuronal nitric-oxide synthase (nNOS) to carboxyl-terminal-binding protein (CtBP) changes the localization of CtBP from the nucleus to the cytosol: a novel function for targeting by the PDZ domain of nNOS. (PubMed id 11590170)1 Riefler G.M. and Firestein B.L. (J. Biol. Chem. 2001)
    279. The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. (PubMed id 11404282)1 Kakoki M....Mattson D.L. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2001)
    280. Heat-shock protein 90 augments neuronal nitric oxide synthase activity by enhancing Ca2+/calmodulin binding. (PubMed id 11284722)1 Song Y....Xia Y. (Biochem. J. 2001)
    281. NOSIP, a novel modulator of endothelial nitric oxide synthase activity. (PubMed id 11149895)1 Dedio J....Mueller-Esterl W. (FASEB J. 2001)
    282. The plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I. (PubMed id 11591728)1 Schuh K....Neyses L. (J. Cell Biol. 2001)
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    284. Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome. (PubMed id 11751185)4 Sullivan K.J....Lima J.J. (Am. J. Respir. Crit. Care Med. 2001)
    285. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. (PubMed id 11022011)4 Ober C....Cox N.J. (Am. J. Hum. Genet. 2000)
    286. AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation. (PubMed id 11052978)1 Chen Z.P....Kemp B.E. (Am. J. Physiol. Endocrinol. Metab. 2000)
    287. The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. (PubMed id 11043403)1 Ort T.... Solimena M. (Eur. J. Cell Biol. 2000)
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    293. EPR studies on the photo-induced intermediates of ferric NO complexes of rat neuronal nitric oxide synthase trapped at low temperature. (PubMed id 10502685)7 Kominami S....Hori H. (J. Biochem. 1999)
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    296. Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome. (PubMed id 10068656)1 Hori K....Clouse K.A. (Blood 1999)
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    490. Insulin feedback actions: complex effects involving isoforms of islet nitric oxide synthase. (PubMed id 15380928)9 Jimenez-Feltstrom J....Salehi A. (Regul. Pept. 2004)
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    492. Comparison between the influence of shocks and endotoxemia on the activation of brain cells that contain nitric oxide. (PubMed id 14725962)9 Seo D.O....Rivier C.L. (Brain Res. 2004)
    493. Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus. (PubMed id 15138761)9 Harvey B.H....Stein D.J. (Psychopharmacology (Berl.) 2004)
    494. Neuronal nitric oxide synthase expression in cerebellar mutant mice. (PubMed id 15543804)9 Abbott L.C. and Nahm S.S. (Cerebellum 2004)
    495. Developmental changes in nitric oxide synthesis in the ovine placenta. (PubMed id 14613894)9 Kwon H....Spencer T.E. (Biol. Reprod. 2004)
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    497. Superoxide dismutase and catalase are required to detect (.-)NO from both coupled and uncoupled neuronal no synthase. (PubMed id 15336315)9 Reif A....Schmidt H.H. (amp 2004)
    498. Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound. (PubMed id 15122883)9 Flinspach M....Poulos T.L. (Biochemistry 2004)
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    500. Protective effect of pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, on ischemia-induced neuronal damage. (PubMed id 15327760)9 Kurosaki R....Araki T. (Neurol. Res. 2004)
    501. Renal disease in rats with type 2 diabetes is associated with decreased renal nitric oxide production. (PubMed id 15490111)9 Erdely A....Baylis C. (Diabetologia 2004)
    502. High expression of nitric oxide synthases is a favorable prognostic sign in non-small cell lung carcinoma. (PubMed id 14678024)9 Puhakka A....Soini Y. (APMIS 2003)
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    505. AQP1 and AQP3, psoriasin, and nitric oxide synthases 1-3 are inflammatory mediators in erythema toxicum neonatorum. (PubMed id 14521551)9 Marchini G....Nielsen S. (Pediatr Dermatol 2003)
    506. Elevated nitric oxide levels in childhood brain tumors. (PubMed id 13680293)9 Kao C.L....Wong T.T. (Childs Nerv Syst 2003)
    507. Pathophysiological significance of neuronal nitric oxide synthase in the gastrointestinal tract. (PubMed id 12768383)9 Takahashi T. (J. Gastroenterol. 2003)
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    530. Nitric oxide mediates LC-3-dependent regulation of fibronectin in ductus arteriosus intimal cushion formation. (PubMed id 10428766)9 Mason C.A....Rabinovitch M. (FASEB J. 1999)
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    532. Comparative localization of heme oxygenase-2 and nitric oxide synthase in the autonomic innervation to the human ductus deferens and seminal vesicle. (PubMed id 10569611)9 Grozdanovic Z. and Goessl C. (J. Urol. 1999)
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    578. NMDA receptor expression and activity in osteoarthritic human articular chondrocytes. (PubMed id 18554934)9 Ramage L....Salter D.M. (Osteoarthr. Cartil. 2008)
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    589. Changes of asymmetric dimethylarginine, nitric oxide, tetrahydrobiopterin, and oxidative stress in patients with acute myocardial infarction by medical treatments. (PubMed id 17726257)9 Yada T....Kajiya F. (Clin. Hemorheol. Microcirc. 2007)
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    598. Nitric oxide has dual opposite roles during early and late phases of apoptosis in cerebellar granule neurons. (PubMed id 17503222)9 Bobba A....Marra E. (Apoptosis 2007)
    599. Role of neuronal nitric oxide in the dopamine deficit of HPRT-deficient mice. (PubMed id 17265179)9 Smith D.W. and Jinnah H.A. (Metab Brain Dis 2007)
    600. Regulation and function of the protein inhibitor of nitric oxide synthase (PIN)/dynein light chain 8 (LC8) in a human mast cell line. (PubMed id 17169380)9 McCauley S.D....Befus A.D. (Life Sci. 2007)
    601. The role of constitutive and inducible nitric oxide synthase in the human brain after subarachnoid hemorrhage. (PubMed id 17369785)9 Berra L.V....Pasqualin A. (J Neurosurg Sci 2007)
    602. Hydrogen sulfide downregulates the aortic L-arginine/nitric oxide pathway in rats. (PubMed id 17634203)9 Geng B....Du J. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007)
    603. Transcripts of aromatase and estrogen receptors and significance of other RNAs in human spermatozoa. (PubMed id 18309897)9 Carreau S. and Isabelle G.D. (Arch. Androl. 2007)
    604. Nitric oxide synthase and superoxide dismutase gene polymorphisms in BehAset disease. (PubMed id 17296902)9 Nakao K....Sakamoto T. (Arch. Ophthalmol. 2007)
    605. Mutual regulation between serine and nitric oxide metabolism in human glioblastoma cells. (PubMed id 16298487)9 Shoji K....Suzuki H. (Neurosci. Lett. 2006)
    606. Mechanisms underlying beta2-adrenoceptor-mediated nitric oxide generation by human umbilical vein endothelial cells. (PubMed id 16873402)9 Queen L.R....Ferro A. (J. Physiol. (Lond.) 2006)
    607. Targeting PDZ domain proteins for treating NMDA receptor-mediated excitotoxicity. (PubMed id 16719811)9 Wen W....Zhang M. (Curr Top Med Chem 2006)
    608. L-arginine chlorination results in the formation of a nonselective nitric-oxide synthase inhibitor. (PubMed id 16717106)9 Yang J....Zhang C. (J. Pharmacol. Exp. Ther. 2006)
    609. Imidazole derivatives as antioxidants and selective inhibitors of nNOS. (PubMed id 16275025)9 Sorrenti V....Vanella A. (Nitric Oxide 2006)
    610. Involvement of nitric oxide synthase and ROS-mediated activation of L-type voltage-gated Ca2+ channels in NMDA-induced DPYSL3 degradation. (PubMed id 16987501)9 Kowara R....Chakravarthy B. (Brain Res. 2006)
    611. Occurrence of nitric oxide synthase in Megoura viciae Buckton (Homoptera, Aphididae): an histochemical and immunohistochemical localisation. (PubMed id 16377581)9 Ganassi S....Mola L. (Eur J Histochem 2005)
    612. Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution. (PubMed id 15748165)9 Abulrob A....Stanimirovic D. (J. Neurochem. 2005)
    613. The formation of a complex between calmodulin and neuronal nitric oxide synthase is determined by ESI-MS. (PubMed id 16849206)9 Shirran S....Barran P. (J R Soc Interface 2005)
    614. Oxidative stress mediates angiotensin II-dependent stimulation of sympathetic nerve activity. (PubMed id 16116043)9 Campese V.M....Huiquin Z. (Hypertension 2005)
    615. Molecular changes in nNOS protein expression within the ventrolateral medulla following transient focal ischemia affect cardiovascular functions. (PubMed id 16084499)9 Ally A....Maher T.J. (Brain Res. 2005)
    616. Reductive activation of Cr(Vi) by nitric oxide synthase. (PubMed id 15892577)9 Porter R....VA!squez-Vivar J. (Chem. Res. Toxicol. 2005)
    617. Hunting oxygen complexes of nitric oxide synthase at low temperature and high pressure. (PubMed id 16126163)9 Marchal S....Lange R. (Biochem. Biophys. Res. Commun. 2005)
    618. Structural and functional diversity in heme monooxygenases. (PubMed id 15475411)9 Poulos T.L. (Drug Metab. Dispos. 2005)
    619. Nitric oxide &quot;at heart&quot;: emerging paradigms after a decade. (PubMed id 15816328)9 Pelat M....Balligand J.L. (Arch Mal Coeur Vaiss 2005)
    620. CAPON expression in skeletal muscle is regulated by position, repair, NOS activity, and dystrophy. (PubMed id 15561099)9 SAcgalat L....Anderson J.E. (Exp. Cell Res. 2005)
    621. Inhibition of neuronal nitric-oxide synthase by phosphorylation at Threonine1296 in NG108-15 neuronal cells. (PubMed id 16214135)9 Song T....Watanabe Y. (FEBS Lett. 2005)
    622. A comparative study of neuronal and inducible nitric oxide synthases: generation of nitric oxide, superoxide, and hydrogen peroxide. (PubMed id 16216417)9 Weaver J....Rosen G.M. (Biochim. Biophys. Acta 2005)
    623. Oxidative state in platelets and erythrocytes in aging and Alzheimer's disease. (PubMed id 15718044)9 Kawamoto E.M....Marcourakis T. (Neurobiol. Aging 2005)
    624. Study on the neurotoxic effects of low-level lead exposure in rats. (PubMed id 15973774)9 Zhu Z.W....Zhao Z.Y. (J Zhejiang Univ Sci B 2005)
    625. Time-dependent aggravation or attenuation of lipopolysaccharide-induced gastric injury by nitric oxide synthase inhibition. (PubMed id 16026802)9 Suliburk J.W....Robinson E.K. (J. Surg. Res. 2005)
    626. L-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide. (PubMed id 15748708)9 Tsai P....Rosen G.M. (Biochem. Pharmacol. 2005)
    627. Neuropsychological functioning in early onset psychotic disorders. (PubMed id 15037336)9 McClellan J....McCurry C. (Schizophr. Res. 2004)
    628. Nitric oxide in health and disease of the respiratory system. (PubMed id 15269335)9 Ricciardolo F.L....Folkerts G. (Physiol. Rev. 2004)
    629. Linkage and association of childhood asthma with the chromosome 12 genes. (PubMed id 14767694)9 Shao C....Matsubara Y. (J. Hum. Genet. 2004)
    630. The role of the arginine-nitric oxide pathway in the pathogenesis of bipolar affective disorder. (PubMed id 14991378)9 Yanik M....Akyol O. (Eur Arch Psychiatry Clin Neurosci 2004)
    631. Redox properties of the isolated flavin mononucleotide- and flavin adenine dinucleotide-binding domains of neuronal nitric oxide synthase. (PubMed id 15323562)9 Garnaud P.E....Daff S. (Biochemistry 2004)
    632. Analysis and significance of mRNA in human ejaculated sperm from normozoospermic donors: relationship to sperm motility and capacitation. (PubMed id 15100385)9 Lambard S....Carreau S. (Mol. Hum. Reprod. 2004)
    633. Activity of inducible and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis. (PubMed id 15330915)9 MenchAcn L....Lorenzo P. (Am. J. Gastroenterol. 2004)
    634. Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons. (PubMed id 15296832)9 Xu Y....Tao Y.X. (Exp. Neurol. 2004)
    635. The potent inducible nitric oxide synthase inhibitor ONO-1714 inhibits neuronal NOS and exerts antinociception in rats. (PubMed id 15245789)9 Sekiguchi F....Kawabata A. (Neurosci. Lett. 2004)
    636. Human neuronal nitric oxide synthase can catalyze one-electron reduction of adriamycin: role of flavin domain. (PubMed id 15196992)9 Fu J....Iyanagi T. (Arch. Biochem. Biophys. 2004)
    637. LDL and HDL affect nitric oxide metabolism in human astrocytoma cells. (PubMed id 15312800)9 Nanetti L....Mazzanti L. (Brain Res. 2004)
    638. NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture. (PubMed id 14720220)9 Choi S.Y....Koh J.Y. (J. Neurochem. 2004)
    639. Nitric oxide produced during ischemia is toxic but crucial to preconditioning-induced ischemic tolerance of neurons in culture. (PubMed id 15098944)9 Kawahara K....Kosugi T. (Neurochem. Res. 2004)
    640. Analysis of the kinetics of CO binding to neuronal nitric oxide synthase by flash photolysis: dual effects of substrates, inhibitors, and tetrahydrobiopterin. (PubMed id 15219987)9 Bengea S....Shimizu T. (J. Inorg. Biochem. 2004)
    641. Characterization of striatal cultures with the effect of QUIN and NMDA. (PubMed id 15099701)9 Kumar U. (Neurosci. Res. 2004)
    642. A review of the L-arginine - nitric oxide - guanylate cyclase pathway as a mediator of lower urinary tract physiology and symptoms. (PubMed id 14633324)9 Stothers L....Christ G.T. (Can J Urol 2003)
    643. [Expression and significance of nitric oxide synthase mRNAs and proteins in giant cell tumors of bone]. (PubMed id 14613648)9 Li H.G....Dong S.K. (Ai Zheng 2003)
    644. Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity. (PubMed id 14609340)9 Hurshman A.R....Marletta M.A. (Biochemistry 2003)
    645. Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes. (PubMed id 12943656)9 Sharma P....Dikshit M. (Biochem. Biophys. Res. Commun. 2003)
    646. Is the arginine-nitric oxide pathway involved in the pathogenesis of schizophrenia? (PubMed id 12707486)9 Yanik M....Akyol O. (Neuropsychobiology 2003)
    647. Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation. (PubMed id 12590926)9 Chen P.F....Wu K.K. (Arch. Biochem. Biophys. 2003)
    648. Changes in sodium, potassium-ATPase induced by repeated fencamfamine: the roles of cyclic AMP-dependent protein kinase and the nitric oxide-cyclic GMP pathway. (PubMed id 14614957)9 Munhoz C.D....Scavone C. (Neuropharmacology 2003)
    649. Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS. (PubMed id 12753090)9 Aquilano K....Ciriolo M.R. (J. Neurochem. 2003)
    650. Detection and localization of two constitutive NOS isoforms in bull spermatozoa. (PubMed id 14651478)9 Meiser H. and Schulz R. (Anat Histol Embryol 2003)
    651. Inhibitory effects and spectral interactions of isomeric methoxyindazoles on recombinant nitric oxide synthases. (PubMed id 14623174)9 Tuynman A....Boucher J.L. (Nitric Oxide 2003)
    652. Gene expression of nitric oxide synthase by human umbilical vein endothelial cells: the effect of fetal plasma from pregnancy with umbilical placental vascular disease. (PubMed id 12504936)9 Wang X....Trudinger B. (BJOG 2003)
    653. Nitric oxide (NO) synthase mRNA expression and NO production via muscarinic acetylcholine receptor-mediated pathways in the CEM, human leukemic T-cell line. (PubMed id 12628472)9 Kamimura Y....Kawashima K. (Life Sci. 2003)
    654. Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen. (PubMed id 12777700)9 Chiueh C....Murphy D. (Endocrine 2003)
    655. 17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection. (PubMed id 12626428)9 Lee S.Y....Chiueh C.C. (FASEB J. 2003)
    656. Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity. (PubMed id 12480166)9 Wegener G....Rosenberg R. (Brain Res. 2003)
    657. [Effect of epidural morphine analgesia on the NO-forming activity of nociceptive neurons of the spinal ganglia and bone marrow]. (PubMed id 14524011)9 Shumatov V.B....Balashova T.V. (Anesteziol Reanimatol 2003)
    658. Novel insight into the mechanisms involved in the regulation of the m1 muscarinic receptor, iNOS and nNOS mRNA levels. (PubMed id 12842132)9 Sterin-Borda L....Borda E. (Neuropharmacology 2003)
    659. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model. (PubMed id 12763743)9 Enkhbaatar P....Traber D. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003)
    660. The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide. (PubMed id 12183447)9 Rosen G.M....Pou S. (J. Biol. Chem. 2002)
    661. Activation of human aortic endothelial cells by LDL from Type 1 diabetic patients: an in vitro study. (PubMed id 12208472)9 Rabini R.A....Mazzanti L. (Atherosclerosis 2002)
    662. The antithyroid agent 6-n-propyl-2-thiouracil is a mechanism-based inactivator of the neuronal nitric oxide synthase isoform. (PubMed id 12392718)9 Wolff D.J. and Marks N. (Arch. Biochem. Biophys. 2002)
    663. Nitrocatechols versus nitrocatecholamines as novel competitive inhibitors of neuronal nitric oxide synthase: lack of the aminoethyl side chain determines loss of tetrahydrobiopterin-antagonizing properties. (PubMed id 11738563)9 Palumbo A....d'Ischia M. (amp 2002)
    664. Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate. (PubMed id 11827745)9 Patel K.B....Everett S.A. (amp 2002)
    665. Influence of estradiol on NADPH diaphorase/neuronal nitric oxide synthase activity and colocalization with progesterone or type II glucocorticoid receptors in ovine hypothalamus. (PubMed id 12193391)9 Dufourny L. and Skinner D.C. (Biol. Reprod. 2002)
    666. Does nitric oxide act as a cellular messenger in muscarinic endometrial secretion in the guinea-pig? (PubMed id 11942918)9 Morlin B....Sjostrand N.O. (Acta Physiol. Scand. 2002)
    667. [Effect of epidural morphine anesthesia on NO-ergic activity of nociceptive neurons of spinal ganglia and spinal cord]. (PubMed id 12462767)9 Shumatov V.B....Balashova T.V. (Anesteziol Reanimatol 2002)
    668. The role of nitric oxide in cigarette smoking and nicotine addiction. (PubMed id 12215243)9 Vleeming W....Opperhuizen A. (amp 2002)
    669. Neuronal nitric oxide synthase: substrate and solvent kinetic isotope effects on the steady-state kinetic parameters for the reduction of 2,6-dichloroindophenol and cytochrome c(3+). (PubMed id 11772017)9 Wolthers K.R. and Schimerlik M.I. (Biochemistry 2002)
    670. Serotonin transporter gene (5-HTTLPR) and major psychoses. (PubMed id 11803453)9 Serretti A....Smeraldi E. (Mol. Psychiatry 2002)
    671. Citrulline is not the major product using the standard &quot;NOS activity&quot; assay on renal cortical homogenates. (PubMed id 11742852)9 Conrad K.P....Novak J. (Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002)
    672. Exercise-induced hyperaemia and leg oxygen uptake are not altered during effective inhibition of nitric oxide synthase with N(G)-nitro-L-arginine methyl ester in humans. (PubMed id 11179408)9 Frandsenn U....Hellsten Y. (J. Physiol. (Lond.) 2001)
    673. Nitric oxide: relation to integrity, injury, and healing of the gastric mucosa. (PubMed id 11376493)9 Calatayud S....Esplugues J.V. (Microsc. Res. Tech. 2001)
    674. Role of abnormal nitric oxide systems in salt-sensitive hypertension. (PubMed id 11411768)9 Manning R.D....Meng S. (Am. J. Hypertens. 2001)
    675. Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin. (PubMed id 11590164)9 Kotsonis P....Schmidt H.H. (J. Biol. Chem. 2001)
    676. Nitroxyl oxidizes NADPH in a superoxide dismutase inhibitable manner. (PubMed id 11275480)9 Reif A....Schmidt H.H. (amp 2001)
    677. Cellular basis of steroid neuroprotection in the wobbler mouse, a genetic model of motoneuron disease. (PubMed id 11569536)9 GonzA!lez Deniselle M.C....De Nicola A.F. (Cell. Mol. Neurobiol. 2001)
    678. Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord. (PubMed id 11344254)9 Catania M.V....Troost D. (J. Neurosci. 2001)
    679. Brain nitric oxide synthase expression is enhanced in the human cervix in labor. (PubMed id 11390250)9 Bao S....Schreiber J. (J. Soc. Gynecol. Investig. 2001)
    680. Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems. (PubMed id 11485379)9 Caro A.A....Stoyanovsky D.A. (Nitric Oxide 2001)
    681. Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: perspective for drugs development. (PubMed id 11172700)9 Barrachina M.D....Esplugues J.V. (Curr. Pharm. Des. 2001)
    682. X-ray absorption spectroscopic analysis of the high-spin ferriheme site in substrate-bound neuronal nitric-oxide synthase. (PubMed id 11481035)9 Cosper N.J....Iwasaki T. (J. Biochem. 2001)
    683. NO message from muscle. (PubMed id 11747089)9 Grozdanovic Z. (Microsc. Res. Tech. 2001)
    684. Alteration of neuronal and endothelial nitric oxide synthase and neuropeptide Y in congenital ureteropelvic junction obstruction. (PubMed id 11396731)9 Knerr I....Rascher W. (Urol. Res. 2001)
    685. Calculated background elimination in quantifying nitric-oxide synthase enzyme activity. (PubMed id 11714509)9 Stonek F....Schneeberger C. (J. Biochem. Biophys. Methods 2001)
    686. Bax and caspases are inhibited by endogenous nitric oxide in dorsal root ganglion neurons in vitro. (PubMed id 11703452)9 Thippeswamy T....Morris R. (Eur. J. Neurosci. 2001)
    687. Time course of expression of three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats. (PubMed id 11255630)9 Niwa M....Yoshida J. (Neurol. Med. Chir. (Tokyo) 2001)
    688. Light-induced photoreceptor apoptosis in vivo requires neuronal nitric-oxide synthase and guanylate cyclase activity and is caspase-3-independent. (PubMed id 11278285)9 Donovan M....Cotter T.G. (J. Biol. Chem. 2001)
    689. Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme. (PubMed id 11125020)9 Demady D.R....Osawa Y. (Mol. Pharmacol. 2001)
    690. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. (PubMed id 11572959)9 BaraA+ano D.E. and Snyder S.H. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    691. The natural substrate for nitric oxide synthase activity. (PubMed id 11746209)9 Alaghband-Zadeh J....Chayen J. (Cell Biochem. Funct. 2001)
    692. Antineutrophil cytoplasm antibody-induced neutrophil nitric oxide production is nitric oxide synthase independent. (PubMed id 11168940)9 Tse W.Y....Adu D. (Kidney Int. 2001)
    693. Temporospatial relationship between the expressions of superoxide dismutase and nitric oxide synthase in the developing human brain: immunohistochemical and immunoblotting analyses. (PubMed id 11761717)9 Takikawa M....Ohama E. (Acta Neuropathol. 2001)
    694. Intra-subunit and inter-subunit electron transfer in neuronal nitric-oxide synthase: effect of calmodulin on heterodimer catalysis. (PubMed id 11395516)9 Sagami I....Shimizu T. (J. Biol. Chem. 2001)
    695. Capsaicin-evoked release of immunoreactive calcitonin gene-related peptide from the spinal cord is mediated by nitric oxide but not by cyclic GMP. (PubMed id 10760483)9 Garry M.G....Davis M.A. (Brain Res. 2000)
    696. Heme oxygenase-2 is present in the sarcolemma region of skeletal muscle fibers and is non-continuously co-localized with nitric oxide synthase-1. (PubMed id 10990066)9 Baum O....Gossrau R. (Acta Histochem. 2000)
    697. [The effect of cardiopulmonary bypass on expression of myocardial nitric oxide synthase in patients for valve replacement]. (PubMed id 12501625)9 Zhou X....Bao T. (Hua Xi Yi Ke Da Xue Xue Bao 2000)
    698. nNOS expression in reactive astrocytes correlates with increased cell death related DNA damage in the hippocampus and entorhinal cortex in Alzheimer's disease. (PubMed id 10964481)9 Simic G....Bogdanovi . (Exp. Neurol. 2000)
    699. Choline acetyltransferase is found in terminals of horizontal cells that label with GABA, nitric oxide synthase and calcium binding proteins in the turtle retina. (PubMed id 10996158)9 Cuenca N....Kolb H. (Brain Res. 2000)
    700. The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin. (PubMed id 10871625)9 Roman L.J....Masters B.S. (J. Biol. Chem. 2000)
    701. ARL 17477, a selective nitric oxide synthase inhibitor, with neuroprotective effects in animal models of global and focal cerebral ischaemia. (PubMed id 10899290)9 O'Neill M.J....Singh J. (Brain Res. 2000)
    702. Nitric oxide modulates fracture healing. (PubMed id 10703937)9 Diwan A.D....Murrell G.A. (J. Bone Miner. Res. 2000)
    703. Heme oxygenase-2 distribution in anorectum: colocalization with neuronal nitric oxide synthase. (PubMed id 10644573)9 Battish R....Rattan S. (Am. J. Physiol. Gastrointest. Liver Physiol. 2000)
    704. Choline is a full agonist in inducing activation of neuronal nitric oxide synthase via the muscarinic M1 receptor. (PubMed id 10657757)9 Carriere J.L. and El-Fakahany E.E. (Pharmacology 2000)
    705. Inhibition of nitric oxide synthase isoforms by tris-malonyl-C(60)-fullerene adducts. (PubMed id 10860539)9 Wolff D.J....Wilson S.R. (Arch. Biochem. Biophys. 2000)
    706. Differential and constitutive expression of neuronal, inducible, and endothelial nitric oxide synthase mRNAs and proteins in pathologically normal human tissues. (PubMed id 11020335)9 Park C.S....Cha Y.N. (Nitric Oxide 2000)
    707. Protein-protein interactions controlling nitric oxide synthases. (PubMed id 10691776)9 Kone B.C. (Acta Physiol. Scand. 2000)
    708. Nitric oxide and intestinal inflammation. (PubMed id 10967157)9 Kubes P. and McCafferty D.M. (Am. J. Med. 2000)
    709. Endogenous nitric oxide is implicated in the regulation of lipolysis through antioxidant-related effect. (PubMed id 11029308)9 Gaudiot N....Giudicelli Y. (Am. J. Physiol., Cell Physiol. 2000)
    710. Expression of nitric oxide synthase isoforms in pregnant human myometrium. (PubMed id 10601500)9 Bartlett S.R....Poston R. (J. Physiol. (Lond.) 1999)
    711. Nitric oxide inhibits the positive chronotropic and inotropic responses to sympathetic nerve stimulation in the isolated guinea-pig atria. (PubMed id 10189110)9 Choate J.K. and Paterson D.J. (J. Auton. Nerv. Syst. 1999)
    712. N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. (PubMed id 10447959)9 Huang H....Silverman R.B. (J. Med. Chem. 1999)
    713. Mechanism of superoxide generation by neuronal nitric-oxide synthase. (PubMed id 10092643)9 Pou S....Rosen G.M. (J. Biol. Chem. 1999)
    714. Electron spin resonance spin-trapping detection of superoxide generated by neuronal nitric oxide synthase. (PubMed id 9919565)9 VA!squez-Vivar J....Kalyanaraman B. (Meth. Enzymol. 1999)
    715. Roles of nitric oxide in brain hypoxia-ischemia. (PubMed id 10320673)9 BolaA+os J.P. and Almeida A. (Biochim. Biophys. Acta 1999)
    716. Expression of constitutive nitric oxide synthase in rat and human gastrointestinal tract. (PubMed id 10395952)9 Fischer H....Konturek J.W. (Biochim. Biophys. Acta 1999)
    717. Effect of redox-active drugs on superoxide generation from nitric oxide synthases: biological and toxicological implications. (PubMed id 10630684)9 VA!squez-Vivar J....Kalyanaraman B. (Free Radic. Res. 1999)
    718. Ultrastructural changes and immunohistochemical localization of nitric oxide synthase, advanced glycation end products and NF-kappa B in aorta of streptozotocin treated Mongolian gerbils. (PubMed id 10401233)9 Nishigaki R....Aramaki T. (Nippon Ika Daigaku Zasshi 1999)
    719. Patterns of innervation of sympathetic vascular neurons by peptide-containing primary sensory fibers. (PubMed id 10320699)9 Zheng Z.L....Kreulen D.L. (Brain Res. 1999)
    720. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity. (PubMed id 9667974)9 Collins J.L....Furfine E.S. (J. Med. Chem. 1998)
    721. Nitric oxide synthase in the heterogeneous population of intramural striated muscle fibres of the human membranous urethral sphincter. (PubMed id 9474237)9 Ho K.M....Andersson K.E. (J. Urol. 1998)
    722. [The synthesis and effects of nitric oxide at the retinal level]. (PubMed id 9932348)9 Cruce M....Leulescu C. (Oftalmologia 1998)
    723. Nitric oxide synthase expression in cervical spinal cord in sporadic amyotrophic lateral sclerosis. (PubMed id 9930658)9 Wong N.K. and Strong M.J. (Eur. J. Cell Biol. 1998)
    724. Neurochemical organization of the macaque retina: effect of TTX on levels and gene expression of cytochrome oxidase and nitric oxide synthase and on the immunoreactivity of Na+ K+ ATPase and NMDA receptor subunit I. (PubMed id 9667011)9 Wong-Riley M.T....Zhang C. (Vision Res. 1998)
    725. Cerebral ischemia/reperfusion increases endothelial nitric oxide synthase levels by an indomethacin-sensitive mechanism. (PubMed id 9428309)9 Beasley T.C....Busija D. (J. Cereb. Blood Flow Metab. 1998)
    726. The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study. (PubMed id 9442050)9 Sagami I. and Shimizu T. (J. Biol. Chem. 1998)
    727. 7-Nitroindazole prevents dopamine depletion caused by low concentrations of MPP+ in rat striatal slices. (PubMed id 9694040)9 Cutillas B....Ambrosio S. (Neurochem. Int. 1998)
    728. Basal ganglia neuronal nitric oxide synthase mRNA expression in Parkinson's disease. (PubMed id 9838046)9 Eve D.J....Foster O.J. (Brain Res. Mol. Brain Res. 1998)
    729. Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter. (PubMed id 9878805)9 Gay R.D....Latchman D.S. (Biochim. Biophys. Acta 1998)
    730. Reaction of neuronal nitric-oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin. (PubMed id 9593685)9 Bec N....Lange R. (J. Biol. Chem. 1998)
    731. Regulation of neuronal nitric oxide synthase mRNA in lordosis-relevant neurons of the ventromedial hypothalamus following short-term estrogen treatment. (PubMed id 9729309)9 Rachman I.M....Cohen R.S. (Brain Res. Mol. Brain Res. 1998)
    732. Nitric oxide synthase structure and electron transfer. (PubMed id 9860925)9 Ortiz de Montellano P.R....Gerber N. (Drug Metab. Dispos. 1998)
    733. Crack cocaine and schizophrenia as risk factors for PPD reactivity in the dually diagnosed. (PubMed id 9789160)9 Taubes T....Westreich L. (J Addict Dis 1998)
    734. Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells. (PubMed id 9449657)9 Armour K.E. and Ralston S.H. (Endocrinology 1998)
    735. Innervation of developing human taste buds. An immunohistochemical study. (PubMed id 9541477)9 Witt M. and Reutter K. (Histochem. Cell Biol. 1998)
    736. Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosum. (PubMed id 9631946)9 Bloch W....Addicks K. (Urol. Res. 1998)
    737. Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells. (PubMed id 9688662)9 Teng B....Makhlouf G.M. (Am. J. Physiol. 1998)
    738. Evidence for a NO synthase in porcine platelets which is stimulated during activation/aggregation. (PubMed id 9222285)9 Berkels R....RAPsen R. (Eur. J. Haematol. 1997)
    739. Role of nitric oxide in SjAPgren's syndrome. (PubMed id 9153549)9 Konttinen Y.T....Polak J.M. (Arthritis Rheum. 1997)
    740. Nitric oxide synthase distribution in the enteric nervous system of children with cardiac achalasia. (PubMed id 9594303)9 Lui H....De Laet M.H. (Chin. Med. J. 1997)
    741. Effect of estrogen on isoforms of nitric oxide synthase: possible mechanism of anti-atherosclerotic effect of estrogen. (PubMed id 9187936)9 Hayashi T....Iguchi A. (Gerontology 1997)
    742. Kinetics of CO ligation with nitric-oxide synthase by flash photolysis and stopped-flow spectrophotometry. (PubMed id 9139703)9 Scheele J.S....Magde D. (J. Biol. Chem. 1997)
    743. S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity. (PubMed id 9056390)9 Matthews R.T....Beal M.F. (Exp. Neurol. 1997)
    744. The neuronal nitric oxide synthase inhibitor 7-nitroindazole also inhibits the monoamine oxidase-B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. (PubMed id 9114971)9 Castagnoli K....Castagnoli N. (Chem. Res. Toxicol. 1997)
    745. Immunohistochemical localization of nitric oxide synthase in human fetal membranes. (PubMed id 9348247)9 Marinoni E....Cosmi E.V. (Acta Obstet Gynecol Scand 1997)
    746. In vivo hypoxia-induced neuronal damage with an enhancement of neuronal nitric oxide synthase immunoreactivity in hippocampus. (PubMed id 9225738)9 Matsuoka Y....Taniguchi T. (Exp. Neurol. 1997)
    747. Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo. (PubMed id 9325253)9 GarcA-a-CardeA+a G....Sessa W.C. (J. Biol. Chem. 1997)
    748. Psychogenic (reactive) and hysterical psychoses: a cross-system reliability study. (PubMed id 9065675)9 Pitta J.C. and Blay S.L. (Acta Psychiatr Scand 1997)
    749. Renal and systemic nitric oxide synthesis in rats with renal mass reduction. (PubMed id 9211360)9 Aiello S....Remuzzi G. (Kidney Int. 1997)
    750. NO synthase isozymes have distinct substrate binding sites. (PubMed id 9376373)9 Fan B....Rousseau D.L. (Biochemistry 1997)
    751. Formation of N delta-cyanoornithine from NG-hydroxy-L-arginine and hydrogen peroxide by neuronal nitric oxide synthase: implications for mechanism. (PubMed id 9398165)9 Clague M.J....Marletta M.A. (Biochemistry 1997)
    752. Immunohistochemical localization of nitric oxide synthase in normal human skin: expression of endothelial-type and inducible-type nitric oxide synthase in keratinocytes. (PubMed id 9065701)9 Shimizu Y....Ueda H. (J. Dermatol. 1997)
    753. Nitric oxide synthase in the human glaucomatous optic nerve head. (PubMed id 9109759)9 Neufeld A.H....Gonzalez M. (Arch. Ophthalmol. 1997)
    754. Evidence for production and functional activity of nitric oxide in seminiferous tubules and blood vessels of the human testis. (PubMed id 9398731)9 Middendorff R....Davidoff M.S. (J. Clin. Endocrinol. Metab. 1997)
    755. Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform. (PubMed id 8842429)9 SzabA^ C....Wolff D.J. (Br. J. Pharmacol. 1996)
    756. Neuronal nitric oxide synthase expression in neuronal cell differentiation. (PubMed id 8929985)9 Ogura T....Esumi H. (Neurosci. Lett. 1996)
    757. Erythrocytes may synthesize their own nitric oxide. (PubMed id 8972893)9 Jubelin B.C. and Gierman J.L. (Am. J. Hypertens. 1996)
    758. Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil. (PubMed id 8710192)9 Tokime T....Kikuchi H. (Neurosci. Lett. 1996)
    759. Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site. (PubMed id 8794766)9 Salerno J.C....Masters B.S. (Biochemistry 1996)
    760. Interaction between ATP-sensitive K+ channels and nitric oxide on pial arterioles in piglets. (PubMed id 8898688)9 Bari F....Busija D.W. (J. Cereb. Blood Flow Metab. 1996)
    761. [Cellular mechanism of opioid tolerance]. (PubMed id 9084551)9 Liaw W.J....Lee H.K. (Acta Anaesthesiol. Sin. 1996)
    762. The fourth EF-hand of calmodulin and its helix-loop-helix components: impact on calcium binding and enzyme activation. (PubMed id 8679587)9 George S.E....Johnson J.D. (Biochemistry 1996)
    763. Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis. (PubMed id 8571963)9 Chung E....Gardiner M. (Am. J. Hum. Genet. 1996)
    764. Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue. (PubMed id 7539291)9 Wang J....Rousseau D.L. (Biochemistry 1995)
    765. Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase. (PubMed id 7499198)9 Salerno J.C....Griffith O.W. (J. Biol. Chem. 1995)
    766. Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants. (PubMed id 7499193)9 Lee C.M....Michel T. (J. Biol. Chem. 1995)
    767. Nitric oxide synthase, immunophilins and poly(ADP-ribose) synthetase: novel targets for the development of neuroprotective drugs. (PubMed id 7477744)9 Zhang J. and Steiner J.P. (Neurol. Res. 1995)
    768. Macrophage NO synthase: characterization of isolated oxygenase and reductase domains reveals a head-to-head subunit interaction. (PubMed id 7530045)9 Ghosh D.K. and Stuehr D.J. (Biochemistry 1995)
    769. NMDA-mediated toxicity to striatal neurons is not reversed by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase. (PubMed id 8821044)9 LAPschmann P.A....Klockgether T. (J. Neural Transm. Suppl. 1995)
    770. Lack of neuronal nitric oxide synthase in nerve fibers of aganglionic intestine: a clue to Hirschsprung's disease. (PubMed id 7533832)9 Larsson L.T....Andersson K.E. (J. Pediatr. Gastroenterol. Nutr. 1995)
    771. Nitric oxide synthesized by gonadotropin-releasing hormone neurons is a mediator of N-methyl-D-aspartate (NMDA)-induced GnRH secretion. (PubMed id 7523101)9 Mahachoklertwattana P....Grumbach M.M. (Endocrinology 1994)
    772. Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity. (PubMed id 7514193)9 Rosenkranz-Weiss P....Pober J.S. (J. Clin. Invest. 1994)
    773. Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. (PubMed id 7514300)9 Dinerman J.L....Snyder S.H. (Proc. Natl. Acad. Sci. U.S.A. 1994)
    774. Catalytic conversion of L-arginine to nitrate by platinum electrodes. (PubMed id 8060312)9 Finkel M.S....Hattler B.G. (Biochem. Biophys. Res. Commun. 1994)
    775. Calmodulin controls neuronal nitric-oxide synthase by a dual mechanism. Activation of intra- and interdomain electron transfer. (PubMed id 7528206)9 Abu-Soud H.M....Stuehr D.J. (J. Biol. Chem. 1994)
    776. 7-Nitro indazole, a neuron-specific nitric oxide synthase inhibitor, produces amnesia in the chick. (PubMed id 10467598)9 HAPlscher C. (amp 1994)
    777. Tetrahydrobiopterin synthesis is induced by LPS in vascular smooth muscle and is rate-limiting for nitric oxide production. (PubMed id 7508166)9 Gross S.S....Hattori Y. (Adv. Exp. Med. Biol. 1993)
    778. Further studies concerning the role of nitric oxide in LTP induction and maintenance. (PubMed id 7683145)9 Musleh W.Y....Baudry M. (Synapse 1993)
    779. Phencyclidine, a psychotomimetic agent and drug of abuse, is a suicide inhibitor of brain nitric oxide synthase. (PubMed id 7688965)9 Osawa Y. and Davila J.C. (Biochem. Biophys. Res. Commun. 1993)
    780. (PubMed id 16712501)9 
    781. Neuronal differentiation of NG108-15 cells has impact on nitric oxide- and membrane (natriuretic peptide receptor-A) cyclic GMP-generating proteins. (PubMed id 20097258)9 MA1ller D....Middendorff R. (Mol. Cell. Endocrinol. 2010)
    782. The roles of nitric oxide synthase and eIF2alpha kinases in regulation of cell cycle upon UVB-irradiation. (PubMed id 20016280)9 Wang L....Wu S. (Cell Cycle 2010)
    783. NOS1AP associates with Scribble and regulates dendritic spine development. (PubMed id 20357130)9 Richier L....Fawcett J.P. (J. Neurosci. 2010)
    784. Nitric oxide synthase activation and oxidative stress, but not intracellular zinc dyshomeostasis, regulate ultraviolet B light-induced apoptosis. (PubMed id 20149802)9 Wang L....Wu S. (Life Sci. 2010)
    785. Decrease in nerve fibre density in human sigmoid colon circular muscle occurs with growth but not aging. (PubMed id 19840272)9 Southwell B.R....Hutson J.M. (Neurogastroenterol. Motil. 2010)
    786. Reactive oxygen and nitrogen species regulate inducible nitric oxide synthase function shifting the balance of nitric oxide and superoxide production. (PubMed id 19932078)9 Sun J....Zweier J.L. (Arch. Biochem. Biophys. 2010)
    787. Pathways involved in the generation of reactive oxygen and nitrogen species during glucose deprivation and its role on the death of cultured hippocampal neurons. (PubMed id 20226235)9 PA!ramo B....Massieu L. (Neuroscience 2010)
    788. Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia. (PubMed id 19684035)9 Sankaralingam S....Davidge S.T. (Cardiovasc. Res. 2010)
    789. Changes in bladder innervation in a mouse model of Alzheimer's disease. (PubMed id 20025962)9 Biallosterski B.T....Gillespie J.I. (J. Chem. Neuroanat. 2010)
    790. Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. (PubMed id 19488045)9 Rao J.S....Kim H.W. (Mol. Psychiatry 2010)
    791. Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. (PubMed id 20337441)9 Delker S.L....Poulos T.L. (J. Am. Chem. Soc. 2010)
    792. Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease. (PubMed id 19797159)9 Brindicci C....Ito K. (Am. J. Respir. Crit. Care Med. 2010)
    793. Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation. (PubMed id 19951943)9 Giroud C....Santolini J. (J. Biol. Chem. 2010)
    794. Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons. (PubMed id 19883643)9 Yang Z.J....Koehler R.C. (Exp. Neurol. 2010)
    795. [Insulin protects the loss of colonic interstitial cells of Cajal and acetylcholine in patients with type 2 diabetes mellitus]. (PubMed id 20450658)9 Tang X....Zhong Y.F. (Zhonghua Nei Ke Za Zhi 2010)
    796. Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase. (PubMed id 20307068)9 Woodward J.J....Marletta M.A. (J. Am. Chem. Soc. 2010)
    797. KMUP-1 attenuates serum deprivation-induced neurotoxicity in SH-SY5Y cells: roles of PKG, PI3K/Akt and Bcl-2/Bax pathways. (PubMed id 19962417)9 Hsu Y.Y....Lo Y.C. (Toxicology 2010)
    798. [The mechanism of peripheral and central sensitization in migraine. A literature review]. (PubMed id 19731814)9 Tajti J. and VAccsei L. (Neuropsychopharmacol Hung 2009)
    799. Impaired myofibrillar function in the soleus muscle of mice with collagen-induced arthritis. (PubMed id 19877058)9 Yamada T....Westerblad H. (Arthritis Rheum. 2009)
    800. Neutralizing a surface charge on the FMN subdomain increases the activity of neuronal nitric-oxide synthase by enhancing the oxygen reactivity of the enzyme heme-nitric oxide complex. (PubMed id 19473991)9 Haque M.M....Stuehr D.J. (J. Biol. Chem. 2009)
    801. Cerebral blood flow regulation by nitric oxide: recent advances. (PubMed id 19293146)9 Toda N....Okamura T. (Pharmacol. Rev. 2009)
    802. Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2. (PubMed id 19073841)9 Mookerjee I....Samuel C.S. (FASEB J. 2009)
    803. Distribution and neurochemical characterization of sensory dorsal root ganglia neurons supplying porcine urinary bladder. (PubMed id 20083855)9 Bossowska A....Majewski M. (J. Physiol. Pharmacol. 2009)
    804. Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups. (PubMed id 19166833)9 Cai Y....Yan X.X. (Exp. Neurol. 2009)
    805. The Child Behavior Checklist (CBCL) and the CBCL-bipolar phenotype are not useful in diagnosing pediatric bipolar disorder. (PubMed id 19232020)9 Diler R.S....Keller M.B. (J Child Adolesc Psychopharmacol 2009)
    806. Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. (PubMed id 19121394)9 Liu H.T....Du Y.G. (Pharmacol. Res. 2009)
    807. Proteomic profiling of x-linked muscular dystrophy. (PubMed id 20082121)9 Lewis C....Ohlendieck K. (J. Muscle Res. Cell. Motil. 2009)
    808. ATP as a mediator of macula densa cell signalling. (PubMed id 19330465)9 Bell P.D....Zhang Z.R. (Purinergic Signal. 2009)
    809. Examining communication between ultraviolet (UV)-damaged cutaneous nerve cells and epidermal keratinocytes in vitro. (PubMed id 19651791)9 Gruber J.V. and Holtz R. (Toxicol Ind Health 2009)
    810. Disrupting specific PDZ domain-mediated interactions for therapeutic benefit. (PubMed id 19732060)9 Houslay M.D. (Br. J. Pharmacol. 2009)
    811. Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping. (PubMed id 19125620)9 Ji H....Silverman R.B. (J. Med. Chem. 2009)
    812. Assessing noxious effects of dietary exposure to methylmercury, PCBs and Se coexisting in environmentally contaminated rice in male mice. (PubMed id 19167073)9 Cheng J....Shi W. (Environ Int 2009)
    813. Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes. (PubMed id 19397961)9 Steinritz D....Kehe K. (Toxicol. Lett. 2009)
    814. Nitric oxide regulates shikonin formation in suspension-cultured Onosma paniculatum cells. (PubMed id 19022805)9 Wu S.J....Yang Y.H. (amp 2009)
    815. Roles of nitric oxide synthase isoforms in cutaneous vasodilation induced by local warming of the skin and whole body heat stress in humans. (PubMed id 19745188)9 Kellogg D.L....Wu Y. (J. Appl. Physiol. 2009)
    816. Postnatal estradiol up-regulates lung nitric oxide synthases and improves lung function in bronchopulmonary dysplasia. (PubMed id 19151197)9 McCurnin D.C....Shaul P.W. (Am. J. Respir. Crit. Care Med. 2009)
    817. Theoretical calculations of a model of NOS indazole inhibitors: interaction of aromatic compounds with Zn-porphyrins. (PubMed id 19857970)9 Elguero J....MarA-a D.S. (amp 2009)
    818. Regulation of interdomain electron transfer in the NOS output state for NO production. (PubMed id 19690675)9 Feng C. and Tollin G. (Dalton Trans 2009)
    819. NADPH-diaphorase activity in the nociceptive pathways of land snail Megalobulimus abbreviatus: the involvement of pedal ganglia. (PubMed id 20012757)9 Rigon P....Xavier L.L. (Invert. Neurosci. 2009)
    820. Effect of age on the enteric nervous system of the human colon. (PubMed id 19220755)9 Bernard C.E....Farrugia G. (Neurogastroenterol. Motil. 2009)
    821. A placebo-controlled study of sildenafil effects on cognition in schizophrenia. (PubMed id 18716761)9 Goff D.C....Walsh J.P. (Psychopharmacology (Berl.) 2009)
    822. Nitric oxide synthase gene therapy: progress and prospects. (PubMed id 19463074)9 O'Connor D.M. and O'Brien T. (Expert Opin Biol Ther 2009)
    823. Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxide synthase inhibitors. (PubMed id 19804982)9 Prins L.H....Malan S.F. (amp 2009)
    824. Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways. (PubMed id 19144839)9 Di S....Tasker J.G. (J. Neurosci. 2009)
    825. Neuron protection as a therapeutic target in acute ischemic stroke. (PubMed id 19849659)9 Tuttolomondo A....Licata G. (Curr Top Med Chem 2009)
    826. The use of ESI-MS to probe the binding of divalent cations to calmodulin. (PubMed id 19297189)9 Shirran S.L. and Barran P.E. (J. Am. Soc. Mass Spectrom. 2009)
    827. Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. (PubMed id 19726651)9 Fan J....Raymond L.A. (J. Neurosci. 2009)
    828. Eusynstyelamides A, B, and C, nNOS inhibitors, from the ascidian Eusynstyela latericius. (PubMed id 19505081)9 Tapiolas D.M....Motti C.A. (J. Nat. Prod. 2009)
    829. AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons. (PubMed id 19570894)9 Murphy B.A....Routh V.H. (Am. J. Physiol., Cell Physiol. 2009)
    830. Combined neuronal and inducible nitric oxide synthase inhibition in ovine acute lung injury. (PubMed id 19050630)9 Lange M....Enkhbaatar P. (Crit. Care Med. 2009)
    831. A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon. (PubMed id 19019012)9 Fornai M....Del Tacca M. (Neurogastroenterol. Motil. 2009)
    832. Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. (PubMed id 19204306)9 Kao W.H....Chakravarti A. (Circulation 2009)
    833. Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(omega)-hydroxy-L-arginine and diatomic ligands. (PubMed id 19791770)9 Doukov T....Poulos T.L. (Biochemistry 2009)
    834. N-Hydroxyguanidines oxidation by a N3S copper-complex mimicking the reactivity of Dopamine beta-Hydroxylase. (PubMed id 19178946)9 Slama P....RAcglier M. (J. Inorg. Biochem. 2009)
    835. Effects of lidocaine on membrane stabilization in harvested vein graft storage. (PubMed id 19198706)9 Unal Y....Pekbay A. (Saudi Med J 2009)
    836. Nitric oxide and cGMP signal transduction positively regulates the motility of human neuronal precursor (NT2) cells. (PubMed id 19627439)9 Tegenge M.A. and Bicker G. (J. Neurochem. 2009)
    837. Endothelial nitric oxide synthase is up-regulated in the umbilical cord in pregnancies complicated with intrauterine growth retardation. (PubMed id 19779107)9 Hracsko Z....Varga I.S. (In Vivo 2009)
    838. Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability. (PubMed id 19268602)9 Lawton G.R....Silverman R.B. (amp 2009)
    839. Elevated levels of NR2A and PSD-95 in the lateral amygdala in depression. (PubMed id 18570704)9 Karolewicz B....Ordway G.A. (Int. J. Neuropsychopharmacol. 2009)
    840. McLean-Harvard International First-Episode Project: two-year stability of DSM-IV diagnoses in 500 first-episode psychotic disorder patients. (PubMed id 19200422)9 Salvatore P....Maggini C. (J Clin Psychiatry 2009)
    841. Prevention of atherosclerosis by interference with the vascular nitric oxide system. (PubMed id 19754387)9 Li H. and FAPrstermann U. (Curr. Pharm. Des. 2009)
    842. Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. (PubMed id 19581842)9 Braekke K....Staff A.C. (Pediatr. Res. 2009)
    843. Nitric oxide and carbon monoxide synthesizing enzymes and soluble guanylyl cyclase within neurons of adult human cardiac ganglia. (PubMed id 19106038)9 Singh S....Wurster R.D. (amp 2009)
    844. Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression. (PubMed id 19221512)9 Martel M.A....Hardingham G.E. (Channels (Austin) 2009)
    845. Tissue kallikrein alleviates glutamate-induced neurotoxicity by activating ERK1. (PubMed id 19598250)9 Liu L....Dong Q. (J. Neurosci. Res. 2009)
    846. GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP. (PubMed id 19447893)9 Kumar S....Black S.M. (Am. J. Physiol. Lung Cell Mol. Physiol. 2009)
    847. Nitric oxide and cyclic nucleotide signal transduction modulates synaptic vesicle turnover in human model neurons. (PubMed id 19807845)9 Tegenge M.A....Bicker G. (J. Neurochem. 2009)
    848. Involvement of the hippocampus and neuronal nitric oxide synthase [correction of synapse] in the gastric electrical stimulation therapy for obesity. (PubMed id 18566870)9 Xu L....Chen J.D. (Obes Surg 2009)
    849. Effect of systemic nitric oxide synthase inhibition on optic disc oxygen partial pressure in normoxia and in hypercapnia. (PubMed id 18676634)9 Petropoulos I.K....Pournaras C.J. (amp 2009)
    850. Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats. (PubMed id 18344376)9 Brosnihan K.B....Ferrario C.M. (Am. J. Physiol. Heart Circ. Physiol. 2008)
    851. The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache. (PubMed id 18789357)9 Olesen J. (amp 2008)
    852. Intracerebroventricular administration of Shiga toxin type 2 altered the expression levels of neuronal nitric oxide synthase and glial fibrillary acidic protein in rat brains. (PubMed id 18675791)9 Boccoli J....Goldstein J. (Brain Res. 2008)
    853. Does diagnostic classification of early-onset psychosis change over follow-up? (PubMed id 17665305)9 Fraguas D....Arango C. (Child Psychiatry Hum Dev 2008)
    854. Metabolic activation of the antitumor drug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by NO synthases. (PubMed id 18370414)9 Chandor A....Boucher J.L. (Chem. Res. Toxicol. 2008)
    855. Key role of tissue plasminogen activator in neurovascular coupling. (PubMed id 18195371)9 Park L....Iadecola C. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    856. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells. (PubMed id 18054268)9 Shimizu S....Kiuchi Y. (amp 2008)
    857. Nitric oxide synthase in critically ischaemic muscle and alterations in isoform expression during revascularization surgery. (PubMed id 17849374)9 Tsui J.C....Dashwood M.R. (Br J Surg 2008)
    858. Antioxidant treatment with alpha-tocopherol improves erectile function in hypertensive rats. (PubMed id 18712056)9 Ushiyama M....Katayama S. (Hypertens. Res. 2008)
    859. Mechanism of alcohol-induced oxidative stress and neuronal injury. (PubMed id 18845238)9 Haorah J....Persidsky Y. (amp 2008)
    860. Control of muscle mitochondria by insulin entails activation of Akt2-mtNOS pathway: implications for the metabolic syndrome. (PubMed id 18335029)9 Finocchietto P....Poderoso J.J. (PLoS ONE 2008)
    861. Recombinant arginine deiminase reduces inducible nitric oxide synthase iNOS-mediated neurotoxicity in a coculture of neurons and microglia. (PubMed id 18627024)9 Yu H.H....Shen L.J. (J. Neurosci. Res. 2008)
    862. The nitric oxide donor LA-419 [S-(6-Nitro-oxi-hexahydro-furo[3,2-b]furan-3-1-il)thioacetate] prevents intestinal dysmotility, bacterial translocation, and inflammation in a rat model of enteritis. (PubMed id 17959746)9 Porras M....Vergara P. (J. Pharmacol. Exp. Ther. 2008)
    863. Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells. (PubMed id 18573259)9 Allen C.L. and Bayraktutan U. (J. Mol. Cell. Cardiol. 2008)
    864. Glutamate signaling proteins and tyrosine hydroxylase in the locus coeruleus of alcoholics. (PubMed id 17481661)9 Karolewicz B....Ordway G.A. (J Psychiatr Res 2008)
    865. Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits. (PubMed id 19111066)9 Andreasen C.H....Hansen T. (BMC Med. Genet. 2008)
    866. Effects of quercetin on hyper-proliferation of gastric mucosal cells in rats treated with chronic oral ethanol through the reactive oxygen species-nitric oxide pathway. (PubMed id 18506933)9 Liu J.L....Ge Y.B. (World J. Gastroenterol. 2008)
    867. Morphometric evaluation of oesophageal wall in patients with nutcracker oesophagus and ineffective oesophageal motility. (PubMed id 18452508)9 Kim H.S....Conklin J.L. (Neurogastroenterol. Motil. 2008)
    868. Interstitial cells of Cajal are innervated by nitrergic nerves and express nitric oxide-sensitive guanylate cyclase in the guinea-pig gastrointestinal tract. (PubMed id 18280665)9 Iino S....Nojyo Y. (Neuroscience 2008)
    869. A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity. (PubMed id 18728399)9 Serulle Y....Ziff E.B. (Channels (Austin) 2008)
    870. Thermodynamic analysis of L-arginine and N omega-hydroxy-L-arginine binding to nitric oxide synthase. (PubMed id 18371313)9 Zakariassen H....rlie M. (Biochim. Biophys. Acta 2008)
    871. Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile. (PubMed id 18502134)9 Cottyn B....Vichard D. (amp 2008)
    872. Immunohistochemical characterization of the innervation of human colonic mesenteric and submucosal blood vessels. (PubMed id 18643894)9 De Fontgalland D....Brookes S.J. (Neurogastroenterol. Motil. 2008)
    873. Lipoproteins obtained from anorexia nervosa patients induce higher oxidative stress in U373MG astrocytes through nitric oxide production. (PubMed id 18292974)9 Vignini A....Mazzanti L. (Neuromolecular Med. 2008)
    874. Akt activates NOS3 and separately restores barrier integrity in H2O2-stressed human cardiac microvascular endothelium. (PubMed id 18931031)9 Dossumbekova A....Vanden Hoek T.L. (Am. J. Physiol. Heart Circ. Physiol. 2008)
    875. Negative regulation of neurogenesis and spatial memory by NR2B-containing NMDA receptors. (PubMed id 18624924)9 Hu M....Zhu D.Y. (J. Neurochem. 2008)
    876. Detrimental effects of hyperandrogenism on uterine functions. (PubMed id 18817896)9 Elia E....Motta A.B. (Int. Immunopharmacol. 2008)
    877. Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle. (PubMed id 18502720)9 Ragionieri L....Palmieri G. (Eur J Histochem 2008)
    878. Endothelial NOS expression within the ventrolateral medulla can affect cardiovascular function during static exercise in stroked rats. (PubMed id 18234158)9 Ally A. and Maher T.J. (Brain Res. 2008)
    879. Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase. (PubMed id 18477512)9 CastaA+o T....Gil C. (amp 2008)
    880. Hypogonadism and erectile dysfunction: an overview. (PubMed id 18087642)9 Gurbuz N....Usta M.F. (Asian J. Androl. 2008)
    881. The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons. (PubMed id 19032594)9 Fountaine T.M....Wade-Martins R. (Eur. J. Neurosci. 2008)
    882. Fluorescent polycyclic ligands for nitric oxide synthase (NOS) inhibition. (PubMed id 18805011)9 Joubert J....Malan S.F. (amp 2008)
    883. Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. (PubMed id 18923045)9 Soriano F.X....Hardingham G.E. (J. Neurosci. 2008)
    884. Cachexia and neuropeptide Y. (PubMed id 18725077)9 Morley J.E. and Farr S.A. (Nutrition 2008)
    885. Generalised cranial artery spasm in human rabies. (PubMed id 18634498)9 Willoughby R.E....Rupprecht C.E. (Dev Biol (Basel) 2008)
    886. Retrospective parent report of psychiatric histories: do checklists reveal specific prodromal indicators for postpubertal-onset pediatric bipolar disorder? (PubMed id 18199242)9 Rucklidge J.J. (Bipolar Disord 2008)
    887. Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production. (PubMed id 18372436)9 Nandi M....Leiper J. (Vasc Med 2008)
    888. Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase. (PubMed id 18519947)9 Grasselli A....Farsetti A. (Circ. Res. 2008)
    889. [The role for oxidative stress in neurodegenerative diseases]. (PubMed id 18306664)9 Shibata N. and Kobayashi M. (Brain Nerve 2008)
    890. Interferon-gamma regulates chemokine expression and release in the human mast cell line HMC1: role of nitric oxide. (PubMed id 17662042)9 Gilchrist M. and Befus A.D. (Immunology 2008)
    891. NOS1AP in schizophrenia. (PubMed id 18474209)9 Brzustowicz L.M. (Curr Psychiatry Rep 2008)
    892. Catalytic reduction of a tetrahydrobiopterin radical within nitric-oxide synthase. (PubMed id 18283102)9 Wei C.C....Stuehr D.J. (J. Biol. Chem. 2008)
    893. Changes in the gastric enteric nervous system and muscle: a case report on two patients with diabetic gastroparesis. (PubMed id 18513423)9 Pasricha P.J....Farrugia G. (BMC Gastroenterol 2008)
    894. Immunohistochemical localisation of pre-synaptic muscarinic receptor subtype-2 (M2r) in the enteric nervous system of guinea-pig ileum. (PubMed id 18247061)9 Harrington A.M....Southwell B.R. (Cell Tissue Res. 2008)
    895. Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans. (PubMed id 18755348)9 Miller J.D....Heistad D.D. (J. Am. Coll. Cardiol. 2008)
    896. Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders. (PubMed id 18392456)9 Oliveira R.M....Deakin J.F. (Braz. J. Med. Biol. Res. 2008)
    897. Is donepezil useful for improving cognitive dysfunction in bipolar disorder? (PubMed id 17825922)9 Kelly T. (J Affect Disord 2008)
    898. Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors. (PubMed id 18321097)9 Ji H....Silverman R.B. (J. Am. Chem. Soc. 2008)
    899. Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients. (PubMed id 18923069)9 Bullock W.M....Perrone-Bizzozero N.I. (Am J Psychiatry 2008)
    900. In vitro antihydatic action of IFN-gamma is dependent on the nitric oxide pathway. (PubMed id 17892399)9 Amri M....Touil-Boukoffa C. (amp 2007)
    901. Role of carbon monoxide in electrically induced non-adrenergic, non-cholinergic relaxations in the guinea-pig isolated whole trachea. (PubMed id 17179955)9 Dellabianca A....Candura S.M. (Br. J. Pharmacol. 2007)
    902. Differential binding of calmodulin domains to constitutive and inducible nitric oxide synthase enzymes. (PubMed id 17580957)9 Spratt D.E....Guillemette J.G. (Biochemistry 2007)
    903. Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site. (PubMed id 17570393)9 Benison G....Barbar E. (J. Mol. Biol. 2007)
    904. Clinical implications of DSM-IV subtyping of bipolar disorders in referred children and adolescents. (PubMed id 17885571)9 Masi G....Toni C. (J Am Acad Child Adolesc Psychiatry 2007)
    905. A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. (PubMed id 17683483)9 Eyerman D.J. and Yamamoto B.K. (J. Neurochem. 2007)
    906. D-Aspartic acid and nitric oxide as regulators of androgen production in boar testis. (PubMed id 16996125)9 Lamanna C....Di Fiore M.M. (Theriogenology 2007)
    907. Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons. (PubMed id 18059133)9 Kim H.J....Lee K.W. (amp 2007)
    908. Versatile regulation of neuronal nitric oxide synthase by specific regions of its C-terminal tail. (PubMed id 18020458)9 Tiso M....Stuehr D.J. (Biochemistry 2007)
    909. Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study. (PubMed id 17459901)9 DzavA-k V....Hochman J.S. (Eur. Heart J. 2007)
    910. Dopamine enhances mtNOS activity: implications in mitochondrial function. (PubMed id 17706939)9 Czerniczyniec A....Lores-Arnaiz S. (Biochim. Biophys. Acta 2007)
    911. Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. (PubMed id 17250678)9 Li Y....Lu J. (J. Neurochem. 2007)
    912. Nonfatal congenital alveolar dysplasia due to abnormalities of NO synthase isoforms. (PubMed id 17590189)9 Hegde S....Greenough A. (Acta Paediatr. 2007)
    913. Neuronal conduction of excitation without action potentials based on ceramide production. (PubMed id 17637828)9 Fasano C....Miolan J.P. (PLoS ONE 2007)
    914. Nitric oxide-NGF mediated PPTA/SP, ADNP, and VIP expression in the peripheral nervous system. (PubMed id 17952636)9 Thippeswamy T....Quinn J.P. (J. Mol. Neurosci. 2007)
    915. The enzymatic machinery for ADMA synthesis and degradation is fully expressed in human adipocytes. (PubMed id 17918140)9 Spoto B....Zoccali C. (J. Nephrol. 2007)
    916. A neonatal mouse model of intestinal perforation: investigating the harmful synergism between glucocorticoids and indomethacin. (PubMed id 18030227)9 Gordon P.V....Aschner J.L. (J. Pediatr. Gastroenterol. Nutr. 2007)
    917. Structural and functional features of choroid epithelium from buffalo brain. (PubMed id 17929274)9 Scala G....Staiano N. (Anat Rec (Hoboken) 2007)
    918. Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway. (PubMed id 17572695)9 Fornai M....Del Tacca M. (Br. J. Pharmacol. 2007)
    919. l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms. (PubMed id 17654045)9 de Sotomayor M.A....Herrera M.D. (Free Radic. Res. 2007)
    920. CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon. (PubMed id 17208221)9 Fornai M....Del Tacca M. (Eur. J. Pharmacol. 2007)
    921. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. (PubMed id 17855605)9 Cui H....Tymianski M. (J. Neurosci. 2007)
    922. Nitric-oxide synthase: a cytochrome P450 family foster child. (PubMed id 17014963)9 Gorren A.C. and Mayer B. (Biochim. Biophys. Acta 2007)
    923. Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant. (PubMed id 17368487)9 Sanelli T....Strong M.J. (J. Neurol. Sci. 2007)
    924. Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. (PubMed id 17293453)9 Mustafa A.K....Snyder S.H. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    925. The child and adolescent first-episode psychosis study (CAFEPS): design and baseline results. (PubMed id 17267179)9 Castro-Fornieles J....Arango C. (Schizophr. Res. 2007)
    926. Does nitric oxide act in the ventromedial preoptic area to mediate oestrogen negative feedback in the seasonally anoestrous ewe? (PubMed id 17641095)9 McManus C.J....Goodman R.L. (Reproduction 2007)
    927. Compound I of nitric oxide synthase: the active site protonation state. (PubMed id 17319660)9 Cho K.B....Shaik S. (J. Am. Chem. Soc. 2007)
    928. Pyloric stenosis in a newborn baby with polycystic kidneys. (PubMed id 17262047)9 Tennakoon J....Alcock G. (J Perinatol 2007)
    929. Cyclic guanosine monophosphate signalling pathway plays a role in neural cell adhesion molecule-mediated neurite outgrowth and survival. (PubMed id 17279552)9 Ditlevsen D.K....Bock E. (J. Neurosci. Res. 2007)
    930. Therapeutic potential of tetrahydrobiopterin for treating vascular and cardiac disease. (PubMed id 17878750)9 Moens A.L. and Kass D.A. (J. Cardiovasc. Pharmacol. 2007)
    931. Modification of the number and phenotype of striatal dopaminergic cells by carotid body graft. (PubMed id 17439984)9 San SebastiA!n W....Luquin M.R. (Brain 2007)
    932. [Increased plasma vasoactive substances and antioxidant enzymes levels in prehypertensive patients]. (PubMed id 17963630)9 Wang Z.G....Wu Z.S. (Zhonghua Xin Xue Guan Bing Za Zhi 2007)
    933. Regionalization of the telencephalon in urodele amphibians and its bearing on the identification of the amygdaloid complex. (PubMed id 18958195)9 Moreno N. and GonzA!lez A. (Front Neuroanat 2007)
    934. Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. (PubMed id 17327434)9 Thum T....Bauersachs J. (Diabetes 2007)
    935. beta-Actin regulates platelet nitric oxide synthase 3 activity through interaction with heat shock protein 90. (PubMed id 17502619)9 Ji Y....Ferro A. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    936. Nitric oxide synthase partial uncoupling as a key switching mechanism for the NO/ONOO- cycle. (PubMed id 17448611)9 Pall M.L. (Med. Hypotheses 2007)
    937. Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap. (PubMed id 17559235)9 Hardy M....Kalyanaraman B. (Chem. Res. Toxicol. 2007)
    938. Involvement of NO generation in aluminum-induced cell death. (PubMed id 17666791)9 Satoh E....Ohyashiki T. (amp 2007)
    939. Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors. (PubMed id 17239601)9 Seo J....Silverman R.B. (amp 2007)
    940. Diagnostic stability over 3 years in a total group of first-episode psychosis patients. (PubMed id 17523030)9 Rahm C. and Cullberg J. (Nord J Psychiatry 2007)
    941. Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity. (PubMed id 17092607)9 Zhuravliova E....Mikeladze D.G. (Neurochem. Int. 2007)
    942. Agmatine : metabolic pathway and spectrum of activity in brain. (PubMed id 17927294)9 Halaris A. and Plietz J. (CNS Drugs 2007)
    943. A mouse model of hypercholesterolemia-induced erectile dysfunction. (PubMed id 17627737)9 Xie D....Annex B.H. (J Sex Med 2007)
    944. Low nitric oxide: a key factor underlying copper-deficiency teratogenicity. (PubMed id 18037129)9 Yang S.J....Uriu-Adams J.Y. (amp 2007)
    945. Tetrahydrobiopterin availability in Parkinson's and Alzheimer's disease; potential pathogenic mechanisms. (PubMed id 17191137)9 Foxton R.H....Heales S.J. (Neurochem. Res. 2007)
    946. Different roles of nitric oxide synthase-1 and -2 between herpetic and postherpetic allodynia in mice. (PubMed id 17997045)9 Sasaki A....Kuraishi Y. (Neuroscience 2007)
    947. Activation of muscarinic cholinergic receptors induces MCF-7 cells proliferation and angiogenesis by stimulating nitric oxide synthase activity. (PubMed id 17611397)9 Fiszman G.L....Sales M.E. (amp 2007)
    948. Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water. (PubMed id 17425297)9 Seo J....Silverman R.B. (J. Med. Chem. 2007)
    949. Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. (PubMed id 17888559)9 Kubo S....Kawabata A. (Toxicology 2007)
    950. Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems. (PubMed id 17933965)9 Palm F....Wilcox C.S. (Am. J. Physiol. Heart Circ. Physiol. 2007)
    951. A potentiating effect of endogenous NO in the physiologic secretion from airway submucosal glands. (PubMed id 17463393)9 Tamada T....Hattori T. (Am. J. Respir. Cell Mol. Biol. 2007)
    952. Testosterone induction of male-typical sexual behavior is associated with increased preoptic NADPH diaphorase and citrulline production in female whiptail lizards. (PubMed id 16838367)9 Sanderson N.S....Crews D. (J. Neurobiol. 2006)
    953. Choroidal innervation in primate eyes. (PubMed id 16289045)9 LA1tjen-Drecoll E. (Exp. Eye Res. 2006)
    954. Nitric oxide and MPP+-induced hydroxyl radical generation. (PubMed id 16463115)9 Obata T. (J Neural Transm 2006)
    955. Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid. (PubMed id 16232120)9 Paradkar P.N. and Roth J.A. (Biochem. J. 2006)
    956. Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury. (PubMed id 16198696)9 Vizzard M.A. (Prog. Brain Res. 2006)
    957. Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase. (PubMed id 17001078)9 Panda K....Stuehr D.J. (J. Biol. Chem. 2006)
    958. Neuronal nitric oxide synthase in the gill of the killifish, Fundulus heteroclitus. (PubMed id 16814584)9 Hyndman K.A....Evans D.H. (amp 2006)
    959. 7-Nitroindazole potentiates the anticonvulsant action of some second-generation antiepileptic drugs in the mouse maximal electroshock-induced seizure model. (PubMed id 16465466)9 Luszczki J.J....Czuczwar S.J. (J Neural Transm 2006)
    960. Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase. (PubMed id 16344367)9 Bevers L.M....Joles J.A. (Hypertension 2006)
    961. Histopathological and immunohistochemical study of the enteric innervations among various types of aganglionoses including isolated and syndromic Hirschsprung disease. (PubMed id 16521475)9 Matsuda H....Nakazato Y. (Neuropathology 2006)
    962. [Study of the changes of acrosomal enzyme and nitric oxide synthase, superoxide dismutase of infertile patients with positive antisperm antibody in seminal plasma]. (PubMed id 16683572)9 Zhang H.F....Zhang C.Y. (Zhonghua Nan Ke Xue 2006)
    963. Endothelial nitric oxide synthase gene intron4 VNTR polymorphism in patients with coronary artery disease in Iran. (PubMed id 17287556)9 Salimi S....Mohebbi A. (Indian J. Med. Res. 2006)
    964. Evidence for nitrite reductase activity in intact mouse Leydig tumor cells. (PubMed id 16952382)9 Panesar N.S. and Chan K.W. (Steroids 2006)
    965. Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes. (PubMed id 17075048)9 Hayashi T....Iguchi A. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    966. Beneficial effects of neuronal nitric oxide synthase in atherosclerosis. (PubMed id 16794230)9 Lowenstein C.J. (Arterioscler. Thromb. Vasc. Biol. 2006)
    967. Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample. (PubMed id 16202394)9 Puri V....Gurling H.M. (Biol. Psychiatry 2006)
    968. Neuroprotective effects of receptor imidazoline 2 and its endogenous ligand agmatine. (PubMed id 17704848)9 Qiu W.W. and Zheng R.Y. (Neurosci Bull 2006)
    969. Intramuscular interstitial cells of Cajal associated with mast cells survive nitrergic nerves in achalasia. (PubMed id 16771771)9 Zarate N....Huizinga J.D. (Neurogastroenterol. Motil. 2006)
    970. Oxygen alters caveolin-1 and nitric oxide synthase-3 functions in ovine fetal and neonatal lung microvascular endothelial cells. (PubMed id 16997880)9 John T.A....Usha Raj J. (Am. J. Physiol. Lung Cell Mol. Physiol. 2006)
    971. Lovastatin reduces apoptosis and downregulates the CD40 expression induced by TNF-alpha in cerebral vascular endothelial cells. (PubMed id 16472124)9 Lin R....Ding C. (Curr Neurovasc Res 2006)
    972. Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas. (PubMed id 16937490)9 Begnami M.D....Soares F.A. (World J. Gastroenterol. 2006)
    973. NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. (PubMed id 16908409)9 Cheah J.H....Snyder S.H. (Neuron 2006)
    974. NANC inhibitory neuromuscular transmission in the hamster distal colon. (PubMed id 17035041)9 El-Mahmoudy A....Takewaki T. (Pharmacol. Res. 2006)
    975. An AMPA glutamatergic receptor activation-nitric oxide synthesis step signals transsynaptic apoptosis in limbic cortex. (PubMed id 16678219)9 Zhou Y....Koliatsos V.E. (Neuropharmacology 2006)
    976. The vascular effect of genistein: what is its mechanism, nitric oxide or PGI2? (PubMed id 16543623)9 Siriviriyakul P....Patumraj S. (Clin. Hemorheol. Microcirc. 2006)
    977. A high-salt diet dissociates NO synthase-3 expression and NO production by the thick ascending limb. (PubMed id 16344378)9 Herrera M....Garvin J.L. (Hypertension 2006)
    978. Sarcomas often express constitutive nitric oxide synthases (NOS) but infrequently inducible NOS. (PubMed id 17122636)9 Cunha I.W....Soares F.A. (amp 2006)
    979. Low plasma nitrite in infantile hypertrophic pyloric stenosis patients. (PubMed id 16758311)9 Huang L.T....Lin J.W. (Dig. Dis. Sci. 2006)
    980. Reactivity of the heme-dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates. (PubMed id 16367758)9 LefA"vre-Groboillot D....Stuehr D.J. (FEBS J. 2006)
    981. Regulation of m1 muscarinic receptors and nNOS mRNA levels by autoantibodies from schizophrenic patients. (PubMed id 16289249)9 Ganzinelli S....Sterin-Borda L. (Neuropharmacology 2006)
    982. Cardiovascular responses and neurotransmitter changes during static muscle contraction following blockade of inducible nitric oxide synthase (iNOS) within the ventrolateral medulla. (PubMed id 16650388)9 Ally A....Maher T.J. (Brain Res. 2006)
    983. Activation of a neural brain-testicular pathway rapidly lowers Leydig cell levels of the steroidogenic acute regulatory protein and the peripheral-type benzodiazepine receptor while increasing levels of neuronal nitric oxide synthase. (PubMed id 16239298)9 Herman M. and Rivier C. (Endocrinology 2006)
    984. Nitric oxide deficiency in the internal anal sphincter of patients with chronic anal fissure. (PubMed id 16052310)9 Lund J.N. (Int J Colorectal Dis 2006)
    985. Urotensin II inhibits electrical activity of hippoCampal CA1 neurons by potentiating the GABA(A) receptor-mediated Cl(-) current. (PubMed id 17687407)9 Wu Y.M....He R.R. (Neurosci Bull 2006)
    986. Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs. (PubMed id 16154200)9 Itzhak Y. and Ali S.F. (amp 2006)
    987. Striatal microinjections of nitric oxide synthase inhibitors and L-arginine fail to exert effects on paroxysmal dystonia in the dtsz mutant. (PubMed id 16423462)9 Sander S.E. and Richter A. (Neurosci. Lett. 2006)
    988. Nitric oxide synthase is up-regulated in muscle fibers in muscular dystrophy. (PubMed id 16876119)9 Punkt K....Buchwalow I.B. (Biochem. Biophys. Res. Commun. 2006)
    989. Neural mechanisms of early postinflammatory dysmotility in rat small intestine. (PubMed id 17109694)9 Demedts I....Tack J. (Neurogastroenterol. Motil. 2006)
    990. In situ measurement of neuronal nitric oxide synthase activity in the spinal cord by NADPH-diaphorase histochemistry. (PubMed id 16085316)9 Xu L....Ito S. (J. Neurosci. Methods 2006)
    991. The effect of different antioxidants on nitric oxide production in hypertensive rats. (PubMed id 17177623)9 KojsovA! S....PechA!novA! O. (Physiol Res 2006)
    992. Early involvement of small inhibitory cortical interneurons in Alzheimer's disease. (PubMed id 16758165)9 Koliatsos V.E....Schneider J.A. (Acta Neuropathol. 2006)
    993. Putative association of the carboxy-terminal PDZ ligand of neuronal nitric oxide synthase gene (CAPON) with schizophrenia in a Colombian population. (PubMed id 16364597)9 Miranda A....Ospina-Duque J. (Schizophr. Res. 2006)
    994. Role of macula densa neuronal nitric oxide synthase in renal diseases. (PubMed id 16575507)9 Tojo A....Fujita T. (Med Mol Morphol 2006)
    995. Neural tube closure depends on nitric oxide synthase activity. (PubMed id 16300634)9 Nachmany A....Weil M. (J. Neurochem. 2006)
    996. Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity. (PubMed id 16860294)9 Mahadevan V.S....Bayraktutan U. (Cardiovasc. Res. 2006)
    997. Tetrahydrobiopterin and cardiovascular disease. (PubMed id 16946131)9 Moens A.L. and Kass D.A. (Arterioscler. Thromb. Vasc. Biol. 2006)
    998. Serum from achalasia patients alters neurochemical coding in the myenteric plexus and nitric oxide mediated motor response in normal human fundus. (PubMed id 16105888)9 Bruley des Varannes S....Neunlist M. (Gut 2006)
    999. A deficiency of gastric interstitial cells of Cajal accompanied by decreased expression of neuronal nitric oxide synthase and substance P in patients with type 2 diabetes mellitus. (PubMed id 17160518)9 Iwasaki H....Hishida A. (J. Gastroenterol. 2006)
    1000. Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: a case-control study. (PubMed id 16626940)9 McGirr A....Turecki G. (Schizophr. Res. 2006)
    1001. Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. (PubMed id 16791854)9 Canzoniero L.M....Di Renzo G. (J. Neurosci. Res. 2006)
    1002. Inhibition of protein synthesis by activation of NMDA receptors in cultured retinal cells: a new mechanism for the regulation of nitric oxide production. (PubMed id 16606372)9 Cossenza M....Paes-de-Carvalho R. (J. Neurochem. 2006)
    1003. Location of interstitial cells and neurotransmitters in the mouse bladder. (PubMed id 16686734)9 Lagou M....Drake M.J. (BJU Int. 2006)
    1004. Nicotinamide increases thyroid radiosensitivity by stimulating nitric oxide synthase expression and the generation of organic peroxides. (PubMed id 16477534)9 Agote Robertson M....Pisarev M.A. (Horm. Metab. Res. 2006)
    1005. Association of the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase gene with schizophrenia in the Chinese Han population. (PubMed id 15707951)9 Zheng Y....He L. (Biochem. Biophys. Res. Commun. 2005)
    1006. Pravastatin activates platelet nitric oxide synthase (NOS) in patients with type 2 diabetes mellitus and NOS activation is accompanied by serine phosphorylation. (PubMed id 16232352)9 Yao K....Ge J.B. (Chin. Med. J. 2005)
    1007. CNTF and BDNF have similar effects on retinal ganglion cell survival but differential effects on nitric oxide synthase expression soon after optic nerve injury. (PubMed id 15790921)9 Zhang C.W....Cui Q. (amp 2005)
    1008. The physiological role of androgens in penile erection: regulation of corpus cavernosum structure and function. (PubMed id 16422801)9 Traish A. and Kim N. (J Sex Med 2005)
    1009. Maturational changes in neuromodulation of central pathways underlying hypoxic ventilatory response. (PubMed id 15950554)9 Simakajornboon N. and Kuptanon T. (amp 2005)
    1010. Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism. (PubMed id 15882473)9 Perrella J. and Bhavnani B.R. (BMC Neurosci 2005)
    1011. Multidimensionally impaired: the good news. (PubMed id 16092914)9 Stayer C....Rapoport J.L. (J Child Adolesc Psychopharmacol 2005)
    1012. Tetrahydrobiopterin as combined electron/proton donor in nitric oxide biosynthesis: cryogenic UV-Vis and EPR detection of reaction intermediates. (PubMed id 16291253)9 Gorren A.C....Mayer B. (Meth. Enzymol. 2005)
    1013. Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway. (PubMed id 16085186)9 Guo S....Zhao B. (amp 2005)
    1014. Determining the chronology and components of psychosis onset: The Nottingham Onset Schedule (NOS). (PubMed id 15978778)9 Singh S.P....Jones P. (Schizophr. Res. 2005)
    1015. Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains. (PubMed id 15238435)9 LA1th H.J....MA1nch G. (Cereb. Cortex 2005)
    1016. Microvascular oxygenation and oxidative stress during postischemic reperfusion. PO2, ROS, and NO during reperfusion. (PubMed id 16594130)9 Bertuglia S. and Giusti A. (Adv. Exp. Med. Biol. 2005)
    1017. Nitric oxide stimulates growth hormone secretion from human fetal pituitaries and cultured pituitary adenomas. (PubMed id 16388095)9 Rubinek T....Shimon I. (Endocrine 2005)
    1018. Changes in renal hemodynamics and structure in the aging kidney; sexual dimorphism and the nitric oxide system. (PubMed id 15820607)9 Baylis C. (Exp. Gerontol. 2005)
    1019. Systemic nitric oxide production rate during hemodialysis and its relationship with nitric oxide-related factors. (PubMed id 16118486)9 Mochizuki S....Kajiya F. (Blood Purif. 2005)
    1020. COMT genetic variation confers risk for psychotic and affective disorders: a case control study. (PubMed id 16232322)9 Funke B....Kucherlapati R. (Behav Brain Funct 2005)
    1021. Peroxynitrite and drug-dependent toxicity. (PubMed id 15691591)9 Denicola A. and Radi R. (Toxicology 2005)
    1022. Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation. (PubMed id 15684422)9 Barrett D.M....Mikkelsen R.B. (J. Biol. Chem. 2005)
    1023. Asymmetric dimethylarginine: a molecule responsible for the coexistence of insulin resistance and atherosclerosis via dual nitric oxide synthase inhibition. (PubMed id 16125868)9 Zsuga J....Bereczki D. (Med. Hypotheses 2005)
    1024. Elevated levels of the NR2C subunit of the NMDA receptor in the locus coeruleus in depression. (PubMed id 15920498)9 Karolewicz B....Ordway G.A. (Neuropsychopharmacology 2005)
    1025. C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase. (PubMed id 16150731)9 Tiso M....Stuehr D.J. (J. Biol. Chem. 2005)
    1026. Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases. (PubMed id 16033258)9 Matter H....Schmidt H.H. (J. Med. Chem. 2005)
    1027. Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype. (PubMed id 16188227)9 Matsumura S....Ito S. (Biochem. Biophys. Res. Commun. 2005)
    1028. Elevated expression of iNOS mRNA and protein in coeliac disease. (PubMed id 15936309)9 Daniels I....Long R.G. ( international journal of clinical chemistry 2005)
    1029. Structure-function studies on nitric oxide synthases. (PubMed id 15598508)9 Li H. and Poulos T.L. (J. Inorg. Biochem. 2005)
    1030. Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro. (PubMed id 15852038)9 Schlemper V....Calixto J.B. (Br. J. Pharmacol. 2005)
    1031. Inhibition of human endothelial cell nitric oxide synthesis by advanced glycation end-products but not glucose: relevance to diabetes. (PubMed id 16022682)9 Xu B....Ferro A. (Clin. Sci. 2005)
    1032. Evidence for a tetrahydrobiopterin deficit in schizophrenia. (PubMed id 16244500)9 Richardson M.A....Clelland J.D. (Neuropsychobiology 2005)
    1033. Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder. (PubMed id 16146415)9 Xu B....Brzustowicz L.M. (PLoS Med. 2005)
    1034. Arteriogenic erectile dysfunction alters protein expression within the cavernosal tissue in an animal model. (PubMed id 16422887)9 De Young L....Brock G. (J Sex Med 2005)
    1035. Sex differences in cell death. (PubMed id 15988750)9 Li H....McCullough L.D. (Ann. Neurol. 2005)
    1036. [Effect of nitric oxide on the efficiency of oxygen consumption by the working skeletal muscle in fatigue]. (PubMed id 15801198)9 Bohuslavs'kyA- A.I.u....Sahach V.F. (Fiziol Zh 2005)
    1037. Inhibition of vascular nitric oxide after rat chronic brain hypoperfusion: spatial memory and immunocytochemical changes. (PubMed id 15703700)9 de la Torre J.C. and Aliev G. (J. Cereb. Blood Flow Metab. 2005)
    1038. Seizure-induced oxidative stress in rat brain regions: blockade by nNOS inhibition. (PubMed id 15680179)9 Rajasekaran K. (Pharmacol. Biochem. Behav. 2005)
    1039. Inhibition of nitric oxide production and protein tyrosine nitration contribute to neuroprotection by a novel calmodulin antagonist, DY-9760e, in the rat microsphere embolism. (PubMed id 16141535)9 Shirakura T....Fukunaga K. (amp 2005)
    1040. A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation. (PubMed id 16123335)9 Kim Y.M....Casadei B. (Circ. Res. 2005)
    1041. The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. (PubMed id 15631993)9 Cao J....Courtney M.J. (J. Cell Biol. 2005)
    1042. Functional activity of mitochondrial nitric oxide synthase. (PubMed id 16291252)9 Valdez L.B....Boveris A. (Meth. Enzymol. 2005)
    1043. Inhibitory effect of sildenafil on gastrointestinal smooth muscle: role of NO-cGMP transduction pathway. (PubMed id 15782818)9 Patil C.S....Kulkarni S.K. (Indian J. Exp. Biol. 2005)
    1044. An NMDA receptor/nitric oxide cascade is involved in cerebellar LTD but is not localized to the parallel fiber terminal. (PubMed id 16120658)9 Shin J.H. and Linden D.J. (J. Neurophysiol. 2005)
    1045. Olfactory deficits, cognition and negative symptoms in early onset psychosis. (PubMed id 16125904)9 Corcoran C....Malaspina D. (Schizophr. Res. 2005)
    1046. Recent advances in the regulation of nitric oxide in the kidney. (PubMed id 15753231)9 Herrera M. and Garvin J.L. (Hypertension 2005)
    1047. Skeletal muscle inflammation and nitric oxide in patients with COPD. (PubMed id 16135718)9 Montes de Oca M....TA!lamo C. (Eur. Respir. J. 2005)
    1048. Distinct roles of oxidative stress and antioxidants in the nucleus dorsalis and red nucleus following spinal cord hemisection. (PubMed id 16095570)9 Xu M....Ng Y.K. (Brain Res. 2005)
    1049. Effects of Lactobacillus GG on genes expression pattern in small bowel mucosa. (PubMed id 15843081)9 Di Caro S....Gasbarrini A. (Dig Liver Dis 2005)
    1050. Role of peroxynitrite in methamphetamine-induced dopaminergic neurodegeneration and neuroprotection by antioxidants and selective NOS inhibitors. (PubMed id 16179512)9 Ali S.F....Itzhak Y. (Ann. N. Y. Acad. Sci. 2005)
    1051. Redox metals and oxidative abnormalities in human prion diseases. (PubMed id 16096758)9 Petersen R.B....Perry G. (Acta Neuropathol. 2005)
    1052. Cardiomyopathy in dystrophin-deficient hearts is prevented by expression of a neuronal nitric oxide synthase transgene in the myocardium. (PubMed id 15917272)9 Wehling-Henricks M....Tidball J.G. (Hum. Mol. Genet. 2005)
    1053. [The development of research on enzymes related to morphine-dependent]. (PubMed id 15931758)9 Hong S.J. (Fa Yi Xue Za Zhi 2005)
    1054. Interactions of alcohol and nitric-oxide synthase in the brain. (PubMed id 16269316)9 Davis R.L. and Syapin P.J. (Brain Res. Brain Res. Rev. 2005)
    1055. Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1. (PubMed id 15899045)9 Otero M....Gualillo O. (amp 2005)
    1056. Understanding nitric oxide physiology in the heart: a nanomedical approach. (PubMed id 16226932)9 Malinski T. (Am. J. Cardiol. 2005)
    1057. Nitric oxide does not mediate promotion of cellular potassium release by phenolphthalein in COS-7 cells. (PubMed id 15053826)9 Mason R.W....Lloyd J.B. (amp 2004)
    1058. Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets. (PubMed id 14766668)9 Fike C.D....Kaplowitz M.R. (Am. J. Physiol. Lung Cell Mol. Physiol. 2004)
    1059. Morphine modulates HIV-1 gp160-induced murine macrophage and human monocyte apoptosis by disparate ways. (PubMed id 14975589)9 Kapasi A.A....Singhal P.C. (J. Neuroimmunol. 2004)
    1060. Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation. (PubMed id 15331636)9 Ciani E....Contestabile A. (J. Cell. Sci. 2004)
    1061. High glucose mediates pro-oxidant and antioxidant enzyme activities in coronary endothelial cells. (PubMed id 15479219)9 Weidig P....Bayraktutan U. (amp 2004)
    1062. Molecular mechanisms of neuroprotective action of immunosuppressants--facts and hypotheses. (PubMed id 15090260)9 Kaminska B....Zawadzka M. (J. Cell. Mol. Med. 2004)
    1063. Neuronal nitric oxide synthase as a novel anti-atherogenic factor. (PubMed id 15153662)9 Tsutsui M. (J. Atheroscler. Thromb. 2004)
    1064. [Pyloric stenosis and neuronal nitric oxide synthase]. (PubMed id 15361336)9 Labie D. and Tamouza R. (Med Sci (Paris) 2004)
    1065. Increased nitric oxide radicals in postmortem brain from patients with schizophrenia. (PubMed id 15954198)9 Yao J.K....Reddy R.D. (Schizophr Bull 2004)
    1066. Pharmacology of nitric oxide: molecular mechanisms and therapeutic strategies. (PubMed id 15134564)9 Domenico R. (Curr. Pharm. Des. 2004)
    1067. Nitric oxide and cerebral ischemic preconditioning. (PubMed id 15261488)9 Huang P.L. (Cell Calcium 2004)
    1068. Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission. (PubMed id 14983060)9 Watkins C.C....Snyder S.H. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    1069. Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase. (PubMed id 15476407)9 Berka V....Tsai A.L. (Biochemistry 2004)
    1070. Anaemia and the brain. (PubMed id 17023891)9 Hare G.M. (Curr Opin Anaesthesiol 2004)
    1071. Highly selective iNOS inhibition and sphincter of Oddi motility in the Australian possum. (PubMed id 15196093)9 Sandstrom P....Svanvik J. (Acta Physiol. Scand. 2004)
    1072. Comparative analysis between cyclic GMP and cyclic AMP signalling in human sperm. (PubMed id 15121877)9 Willipinski-Stapelfeldt B....MA1ller D. (Mol. Hum. Reprod. 2004)
    1073. Affective disorders in the first-degree relatives of bipolar probands: results from the South Island Bipolar Study. (PubMed id 15124146)9 Joyce P.R....Olds R.J. (Compr Psychiatry 2004)
    1074. Measurement of nitric oxide synthase activity in vivo and in vitro by gas chromatography-mass spectrometry. (PubMed id 15199238)9 Tsikas D. (Methods Mol. Biol. 2004)
    1075. Biology and chemistry of the inhibition of nitric oxide synthases by pteridine-derivatives as therapeutic agents. (PubMed id 15224385)9 Matter H. and Kotsonis P. (Med Res Rev 2004)
    1076. Point of NO return for nitrergic nerves in diabetes: a new insight into diabetic complications. (PubMed id 15579064)9 Cellek S. (Curr. Pharm. Des. 2004)
    1077. Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. (PubMed id 15486091)9 Khan S.A....Hare J.M. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    1078. Immunohistochemical classification and functional morphology of human choroidal ganglion cells. (PubMed id 14744873)9 May C.A....LA1tjen-Drecoll E. (amp 2004)
    1079. Roles of mitochondria in health and disease. (PubMed id 14749273)9 Duchen M.R. (Diabetes 2004)
    1080. Phencyclidine-induced behaviour in mice prevented by methylene blue. (PubMed id 14748849)9 Klamer D....Svensson L. (amp 2004)
    1081. Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified. (PubMed id 15121480)9 Addington A.M....Rapoport J.L. (Biol. Psychiatry 2004)
    1082. Immune system-mediated endothelial damage is associated with NO and antioxidant system disorders. (PubMed id 15552269)9 DjordjeviA8 V.B....StojanoviA8 I. (Clin. Chem. Lab. Med. 2004)
    1083. Oxidative stress and antioxidant therapy: their impact in diabetes-associated erectile dysfunction. (PubMed id 15292117)9 De Young L....Brock G.B. (J. Androl. 2004)
    1084. A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis. (PubMed id 14966111)9 Panda K....Stuehr D.J. (J. Biol. Chem. 2004)
    1085. Influence of L-NAME on pulmonary O2 uptake kinetics during heavy-intensity cycle exercise. (PubMed id 14657038)9 Jones A.M....Campbell I.T. (J. Appl. Physiol. 2004)
    1086. Low nNOS protein in the locus coeruleus in major depression. (PubMed id 15569249)9 Karolewicz B....Ordway G.A. (J. Neurochem. 2004)
    1087. Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath. (PubMed id 15333851)9 Lane C....Stick S. (Thorax 2004)
    1088. Involvement of the NMDA receptor/nitric oxide signal pathway in platelet-activating factor-induced neurotoxicity. (PubMed id 15076749)9 Xu Y. and Tao Y.X. (Neuroreport 2004)
    1089. Comparative anatomy of nitrergic intrinsic choroidal neurons (ICN) in various avian species. (PubMed id 14729351)9 Schroedl F....Neuhuber W.L. (Exp. Eye Res. 2004)
    1090. Long-term observational comparison of risperidone and olanzapine in bipolar disorder. (PubMed id 15328900)9 Ghaemi S.N....Goodwin F.K. (Ann Clin Psychiatry 2004)
    1091. The effect on the intestines of continuous release of methylene blue from a drug delivery system: an experimental study in a chick embryo gastroschisis model. (PubMed id 15338173)9 Denli O....Cedden F. (Pediatr. Surg. Int. 2004)
    1092. Co-expression and modulation of neuronal and endothelial nitric oxide synthase in human endothelial cells. (PubMed id 15522271)9 Bachetti T....Ferrari R. (J. Mol. Cell. Cardiol. 2004)
    1093. Habituation of acoustic startle is disrupted by psychotomimetic drugs: differential dependence on dopaminergic and nitric oxide modulatory mechanisms. (PubMed id 15173930)9 Klamer D....Svensson L. (Psychopharmacology (Berl.) 2004)
    1094. Neuroanatomy of the human female lower urogenital tract. (PubMed id 15201770)9 Yucel S....Baskin L.S. (J. Urol. 2004)
    1095. The effect of divalent cations on neuronal nitric oxide synthase activity. (PubMed id 15240894)9 Weaver J....Rosen G.M. (Toxicol. Sci. 2004)
    1096. Effects of adolescent manic symptoms on agreement between youth, parent, and teacher ratings of behavior problems. (PubMed id 15571790)9 Youngstrom E.A....Calabrese J.R. (J Affect Disord 2004)
    1097. Influence of nitric oxide synthase inhibition on pulmonary O2 uptake kinetics during supra-maximal exercise in humans. (PubMed id 15358808)9 Wilkerson D.P....Jones A.M. (J. Physiol. (Lond.) 2004)
    1098. Repeated application of ketamine to rats induces changes in the hippocampal expression of parvalbumin, neuronal nitric oxide synthase and cFOS similar to those found in human schizophrenia. (PubMed id 15183509)9 Keilhoff G....Bernstein H.G. (Neuroscience 2004)
    1099. Pattern of lipofuscin pigmentation in nitrergic and non-nitrergic, neurofilament immunoreactive myenteric neuron types of human small intestine. (PubMed id 14663589)9 Brehmer A....Neuhuber W. (Histochem. Cell Biol. 2004)
    1100. Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model. (PubMed id 14662521)9 Jarabek B.R....Wolfe B.B. (Brain 2004)
    1101. Inhibition of nuclear factor kappa B activation and inducible nitric oxide synthase transcription by prolonged exposure to high glucose in the human keratinocyte cell line HaCaT. (PubMed id 15099358)9 Nakai K....Kosaka H. (Br. J. Dermatol. 2004)
    1102. Molecular pathophysiology and gene therapy of aging-related erectile dysfunction. (PubMed id 15582286)9 Gonzalez-Cadavid N.F. and Rajfer J. (Exp. Gerontol. 2004)
    1103. Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22. (PubMed id 15065015)9 Brzustowicz L.M....Bassett A.S. (Am. J. Hum. Genet. 2004)
    1104. The effect of e-, i-, and n-nitric oxide synthase inhibition on colonic motility in normal and muscular dystrophy (mdx) mice. (PubMed id 15760488)9 Tameyasu T....Ogihara K. (Jpn. J. Physiol. 2004)
    1105. The function of the small insertion in the hinge subdomain in the control of constitutive mammalian nitric-oxide synthases. (PubMed id 15210721)9 Jones R.J....Salerno J.C. (J. Biol. Chem. 2004)
    1106. Increased neuronal nitric oxide synthase-derived NO production in the failing human heart. (PubMed id 15110495)9 Damy T....Heymes C. (Lancet 2004)
    1107. Radical reactions of nitric oxide synthases. (PubMed id 15777011)9 Stuehr D.J....Getzoff E.D. (Biochem. Soc. Symp. 2004)
    1108. Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase. (PubMed id 15160393)9 Scorziello A....Di Renzo G.F. (J. Neurosci. Res. 2004)
    1109. Serum nitric oxide metabolite levels and the effect of antipsychotic therapy in schizophrenia. (PubMed id 15610909)9 Taneli F....Ari Z. (Arch. Med. Res. 2004)
    1110. Nitric oxide as putative second messenger in nerve-induced cervical gland secretion in the guinea-pig. (PubMed id 15488116)9 MAPrlin B....SjAPstrand N.O. (Acta Obstet Gynecol Scand 2004)
    1111. Vulnerability of central neurons to secondary insults after in vitro mechanical stretch. (PubMed id 15371512)9 Arundine M....Tymianski M. (J. Neurosci. 2004)
    1112. Stretch-induced nitric oxide modulates mechanical properties of skeletal muscle cells. (PubMed id 15044149)9 Zhang J.S....Truskey G.A. (Am. J. Physiol., Cell Physiol. 2004)
    1113. Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants. (PubMed id 15193280)9 GonzA!lez-Polo R.A....Fuentes J.M. (Cell Biol. Int. 2004)
    1114. The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain. (PubMed id 15180983)9 Konas D.W....Stuehr D.J. (J. Biol. Chem. 2004)
    1115. Redox processes underlying the vascular repair reaction. (PubMed id 14961189)9 Leite P.F....Laurindo F.R. (World J Surg 2004)
    1116. Antioxidative response for nitric oxide production in breast carcinoma. (PubMed id 15375496)9 Karihtala P....Soini Y. (Oncol. Rep. 2004)
    1117. No association between a neuronal nitric oxide synthase (NOS1) gene polymorphism on chromosome 12q24 and bipolar disorder. (PubMed id 14681919)9 ButtenschAPn H.N....Kruse T.A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2004)
    1118. Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling. (PubMed id 15150612)9 Renaudin K....Jarry A. (Br. J. Cancer 2004)
    1119. Alterations in soluble guanylate cyclase content and modulation by nitric oxide in liver disease. (PubMed id 15312989)9 Rodrigo R....Felipo V. (Neurochem. Int. 2004)
    1120. Tetrahydrobiopterin binding to aromatic amino acid hydroxylases. Ligand recognition and specificity. (PubMed id 15537351)9 Teigen K....MartA-nez A. (J. Med. Chem. 2004)
    1121. Mitochondrial nitric-oxide synthase: enzyme expression, characterization, and regulation. (PubMed id 15377869)9 Haynes V....Giulivi C. (J. Bioenerg. Biomembr. 2004)
    1122. Interactions between NO and O2 in the microcirculation: a mathematical analysis. (PubMed id 15219419)9 Lamkin-Kennard K.A....Jaron D. (Microvasc. Res. 2004)
    1123. Detection of nitric oxide synthase (NOS) immunoreactive neurons in the human septal area: a matter of method? (PubMed id 15261331)9 Bernstein H.G....LA1th H.J. (J. Chem. Neuroanat. 2004)
    1124. The post-ischemic administration of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, prevents delayed neuronal death in gerbil hippocampus. (PubMed id 15359085)9 Hashiguchi A....Fukunaga K. (J. Pharmacol. Sci. 2004)
    1125. Vascular endothelial growth factor stimulates differential signaling pathways in in vivo microcirculation. (PubMed id 15155260)9 Aramoto H....DurA!n W.N. (Am. J. Physiol. Heart Circ. Physiol. 2004)
    1126. Heme distortion modulated by ligand-protein interactions in inducible nitric-oxide synthase. (PubMed id 15066989)9 Li D....Rousseau D.L. (J. Biol. Chem. 2004)
    1127. Deadly conversations: nuclear-mitochondrial cross-talk. (PubMed id 15377859)9 Dawson V.L. and Dawson T.M. (J. Bioenerg. Biomembr. 2004)
    1128. Signaling in the mammalian circadian clock: the NO/cGMP pathway. (PubMed id 15312987)9 Golombek D.A....Ferreyra G.A. (Neurochem. Int. 2004)
    1129. Nitric oxide synthase inhibition with L-NAME reduces maximal oxygen uptake but not gas exchange threshold during incremental cycle exercise in man. (PubMed id 15284344)9 Jones A.M....Campbell I.T. (J. Physiol. (Lond.) 2004)
    1130. Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin. (PubMed id 15182855)9 Topal G....David-Dufilho M. (amp 2004)
    1131. Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma. (PubMed id 14514933)9 Ricciardolo F.L....Sterk P.J. (Thorax 2003)
    1132. Disruption of the NMDA receptor-PSD-95 interaction in hippocampal neurons with no obvious physiological short-term effect. (PubMed id 14529713)9 Lim I.A....Hell J.W. (Neuropharmacology 2003)
    1133. Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice. (PubMed id 12788381)9 Barouch L.A....Hare J.M. (J. Mol. Cell. Cardiol. 2003)
    1134. The role of tetrahydrobiopterin in superoxide generation from eNOS: enzymology and physiological implications. (PubMed id 12653200)9 VA!squez-Vivar J....MartA!sek P. (Free Radic. Res. 2003)
    1135. Immunohistochemical study of the expression of cytokines and nitric oxide synthases in brains of patients with dementia with Lewy bodies. (PubMed id 12722921)9 Katsuse O....Kosaka K. (Neuropathology 2003)
    1136. Urease enhances the formation of iron nitrosyl hemoglobin in the presence of hydroxyurea. (PubMed id 12880948)9 Lockamy V.L....Kim-Shapiro D.B. (Biochim. Biophys. Acta 2003)
    1137. [Mechanisms of nitric oxide synthesis and action in cells]. (PubMed id 12829875)9 Arzumanian V....Kevelaitis E. (Medicina (Kaunas) 2003)
    1138. New insights on oxidative stress and diabetic complications may lead to a &quot;causal&quot; antioxidant therapy. (PubMed id 12716823)9 Ceriello A. (Diabetes Care 2003)
    1139. p75 neurotrophin receptor mediates neurotrophin activation of NF-kappa B and induction of iNOS expression in P19 neurons. (PubMed id 12672017)9 Burke M.A. and Bothwell M. (J. Neurobiol. 2003)
    1140. The DDAH/ADMA/NOS pathway. (PubMed id 14664901)9 Tran C.T....Vallance P. (Atheroscler Suppl 2003)
    1141. Reciprocal variations of nNOS and HSP90 are associated with fasting in gastrointestinal tract of the piglet. (PubMed id 12643617)9 Grongnet J.F. and David J.C. (Dig. Dis. Sci. 2003)
    1142. Utilization of exogenous tetrahydrobiopterin in nitric oxide synthesis in human neuroblastoma cell line. (PubMed id 14625030)9 Choi H.J....Hwang O. (Neurosci. Lett. 2003)
    1143. Neuronal nitric oxide synthase: its role and regulation in macula densa cells. (PubMed id 14514725)9 KovA!cs G....Bell P.D. (J. Am. Soc. Nephrol. 2003)
    1144. MK-801 and 7-Ni attenuate the activation of brain NF-kappa B induced by LPS. (PubMed id 14614955)9 Glezer I....Scavone C. (Neuropharmacology 2003)
    1145. Chimeric enzymes of cytochrome P450 oxidoreductase and neuronal nitric-oxide synthase reductase domain reveal structural and functional differences. (PubMed id 12730215)9 Roman L.J....Masters B.S. (J. Biol. Chem. 2003)
    1146. Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. (PubMed id 14642398)9 Gil J....Rego A.C. (amp 2003)
    1147. Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis. (PubMed id 14506635)9 Soini Y....Satta J. (Hum. Pathol. 2003)
    1148. Premorbid functioning in early-onset psychotic disorders. (PubMed id 12921474)9 McClellan J....Hlastala S.A. (J Am Acad Child Adolesc Psychiatry 2003)
    1149. NADPH-diaphorase staining reveals new types of interneurons in human putamen. (PubMed id 12865162)9 Johannes S....Lauer M. (Brain Res. 2003)
    1150. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. (PubMed id 12845153)9 Brown G.C. and Bal-Price A. (Mol. Neurobiol. 2003)
    1151. Gene expression in macrophage-rich inflammatory cell infiltrates in human atherosclerotic lesions as studied by laser microdissection and DNA array: overexpression of HMG-CoA reductase, colony stimulating factor receptors, CD11A/CD18 integrins, and interleukin receptors. (PubMed id 14576072)9 Tuomisto T.T....YlAo-Herttuala S. (Arterioscler. Thromb. Vasc. Biol. 2003)
    1152. Early postdenervation depolarization is controlled by acetylcholine and glutamate via nitric oxide regulation of the chloride transporter. (PubMed id 12675147)9 Vyskocil F. (Neurochem. Res. 2003)
    1153. Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans. (PubMed id 12509498)9 Hillig T....Hellsten Y. (J. Physiol. (Lond.) 2003)
    1154. Novel inhibitors of neuronal nitric oxide synthase. (PubMed id 12709574)9 Di Giacomo C....Vanella A. (Exp. Biol. Med. (Maywood) 2003)
    1155. Long-term regulation of N-methyl-D-aspartate receptor subunits and associated synaptic proteins following hippocampal synaptic plasticity. (PubMed id 12732245)9 Williams J.M....Abraham W.C. (Neuroscience 2003)
    1156. Distinct influence of N-terminal elements on neuronal nitric-oxide synthase structure and catalysis. (PubMed id 12847099)9 Panda K....Stuehr D.J. (J. Biol. Chem. 2003)
    1157. Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin. (PubMed id 12734191)9 Elzaouk L....Thony B. (J. Biol. Chem. 2003)
    1158. Subsecond separation of cellular flavin coenzymes by microchip capillary electrophoresis with laser-induced fluorescence detection. (PubMed id 14735989)9 Liu B.F....Terabe S. (J Chromatogr A 2003)
    1159. Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes. (PubMed id 12898015)9 Esberg L.B. and Ren J. (Diabetologia 2003)
    1160. Neurochemical coding of myenteric neurones in the human gastric fundus. (PubMed id 14651601)9 Pimont S....Neunlist M. (Neurogastroenterol. Motil. 2003)
    1161. [Effect of insulin on the expression of platelet membrane glycoprotein II b/III a and its mechanisms]. (PubMed id 13129728)9 Peng B.Y....Cai D.H. (Di Yi Jun Yi Da Xue Xue Bao 2003)
    1162. Behavioral and biochemical studies on chronic mild stress models in rats treated with a Chinese traditional prescription Banxia-houpu decoction. (PubMed id 14575813)9 Li J.M....Tan W.Z. (Life Sci. 2003)
    1163. Nitrergic hyperinnervation in appendicitis and in appendices histologically classified as normal. (PubMed id 12708900)9 Nemeth L....Puri P. (amp 2003)
    1164. Deferoxamine reduces and nitric oxide synthase inhibition increases neutrophil-mediated myotube injury. (PubMed id 12898213)9 McLoughlin T.J....Pizza F.X. (Cell Tissue Res. 2003)
    1165. Nitric oxide and cyclic nucleotides are regulators of neuronal migration in an insect embryo. (PubMed id 12874120)9 Haase A. and Bicker G. (Development 2003)
    1166. Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment. (PubMed id 12829186)9 O'Kane P.D....Ferro A. (Cardiovasc. Res. 2003)
    1167. Effect of nitric oxide synthase inhibition and saline administration on blood pressure and renal sodium handling during experimental sepsis in rats. (PubMed id 14669849)9 CAcsar de Oliveira P....Gontijo J.A. (Ren Fail 2003)
    1168. Interactive effects of PTH and mechanical stress on nitric oxide and PGE2 production by primary mouse osteoblastic cells. (PubMed id 12746215)9 Bakker A.D....Burger E.H. (Am. J. Physiol. Endocrinol. Metab. 2003)
    1169. Postanoxic functional recovery of the developing heart is slightly altered by endogenous or exogenous nitric oxide. (PubMed id 14577576)9 Terrand J....Raddatz E. (Mol. Cell. Biochem. 2003)
    1170. Nitric oxide inhibits the firing activity of hypothalamic paraventricular neurons that innervate the medulla oblongata: role of GABA. (PubMed id 12710969)9 Li Y....Stern J.E. (Neuroscience 2003)
    1171. Nitric oxide synthases: domain structure and alignment in enzyme function and control. (PubMed id 12456347)9 Ghosh D.K. and Salerno J.C. (Front. Biosci. 2003)
    1172. Two modes of binding of N-hydroxyguanidines to NO synthases: first evidence for the formation of iron-N-hydroxyguanidine complexes and key role of tetrahydrobiopterin in determining the binding mode. (PubMed id 12667076)9 LefA"vre-Groboillot D....Mansuy D. (Biochemistry 2003)
    1173. Relaxant effects of parathyroid hormone and parathyroid hormone-related peptides on oviduct motility in birds and mammals: possible role of nitric oxide. (PubMed id 12928013)9 Francis M....Brown J.F. (Gen. Comp. Endocrinol. 2003)
    1174. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells. (PubMed id 12726922)9 Shimizu S....Kiuchi Y. (amp 2003)
    1175. Syncoilin accumulation in two patients with desmin-related myopathy. (PubMed id 12467731)9 Howman E.V....Davies K.E. (Neuromuscul. Disord. 2003)
    1176. Stimulation of perivascular nitric oxide synthesis by oxygen. (PubMed id 12505879)9 Thom S.R....Buerk D.G. (Am. J. Physiol. Heart Circ. Physiol. 2003)
    1177. Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics. (PubMed id 12853458)9 Fang M....Johns R.A. (J. Biol. Chem. 2003)
    1178. Relocalization of neuronal nitric oxide synthase (nNOS) as a marker for complete restoration of the dystrophin associated protein complex in skeletal muscle. (PubMed id 12467729)9 Wells K.E....Wells D.J. (Neuromuscul. Disord. 2003)
    1179. Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide. (PubMed id 12507730)9 Melo J.B....Oliveira C.R. (Neurosci. Res. 2003)
    1180. [A case report of factitious disorder with hallucinations]. (PubMed id 14569475)9 Yildiz M. and Torun F. (Turk Psikiyatri Derg 2003)
    1181. Estrogen selectively up-regulates eNOS and nNOS in reproductive arteries by transcriptional mechanisms. (PubMed id 12759149)9 Rosenfeld C.R....Liu X.t. (J. Soc. Gynecol. Investig. 2003)
    1182. Hypoxia-induced caspase-3 activation and DNA fragmentation in cortical neurons of newborn piglets: role of nitric oxide. (PubMed id 12938857)9 Parikh N.A....Mishra O.P. (Neurochem. Res. 2003)
    1183. Localization of the nitric oxide/cGMP signaling pathway-related genes and influences of morpholino knock-down of soluble guanylyl cyclase on medaka fish embryogenesis. (PubMed id 12655181)9 Yamamoto T....Suzuki N. (Zool. Sci. 2003)
    1184. Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease. (PubMed id 12902916)9 Morris C.R....Kuypers F.A. (J. Pediatr. Hematol. Oncol. 2003)
    1185. Role of nitric oxide in the modulation of angiogenesis. (PubMed id 12570800)9 Morbidelli L....Ziche M. (Curr. Pharm. Des. 2003)
    1186. Single-turnover of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: proposed role for tetrahydrobiopterin as a proton donor. (PubMed id 14514694)9 Sorlie M....Mayer B. (J. Biol. Chem. 2003)
    1187. Nociceptin immunoreactivity and receptor mRNA in the human trigeminal ganglion. (PubMed id 12576178)9 Hou M....Edvinsson L. (Brain Res. 2003)
    1188. An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity. (PubMed id 12785010)9 Matsumoto N....Yoshikawa T. (Shock 2003)
    1189. Identifying bipolar disorders in individuals with intellectual disability. (PubMed id 12558693)9 Cain N.N....Deutsch L. (J Intellect Disabil Res 2003)
    1190. [Metalloporphyrin catalyzed biomimetic oxidation potentials: potential uses and applications]. (PubMed id 15112438)9 Balogh G.T. and KeserA1 G.M. (Acta Pharm Hung 2003)
    1191. Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes. (PubMed id 12913068)9 Raby B.A....Weiss S.T. (Hum. Mol. Genet. 2003)
    1192. Gene-specific chromatin damage in human spermatozoa can be blocked by antioxidants that target mitochondria. (PubMed id 14656402)9 Lamond S....Banerjee S. (Reprod. Biomed. Online 2003)
    1193. Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase. (PubMed id 12600215)9 Voegtle H.L....Dawson J.H. (Biochemistry 2003)
    1194. Nitric-oxide synthase (NOS) reductase domain models suggest a new control element in endothelial NOS that attenuates calmodulin-dependent activity. (PubMed id 12805387)9 Knudsen G.M....Ortiz de Montellano P.R. (J. Biol. Chem. 2003)
    1195. [Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase]. (PubMed id 11862754)9 Masuda H. and Azuma H. (Nippon Yakurigaku Zasshi 2002)
    1196. Vasculoprotective roles of neuronal nitric oxide synthase. (PubMed id 12397095)9 Morishita T....Nakashima Y. (FASEB J. 2002)
    1197. Heme oxygenase and nitric oxide synthase in human middle ear epithelium indicates local carbon monoxide and nitric oxide production. (PubMed id 12403126)9 Andersson J.A....Cardell L.O. (Acta Otolaryngol. 2002)
    1198. Effects of intracerebroventricular administration of 7-nitroindazole on tolerance to ethanol. (PubMed id 11849822)9 Wazlawik E. and Morato G.S. (Brain Res. Bull. 2002)
    1199. Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis. (PubMed id 12362409)9 Heath P.R. and Shaw P.J. (amp 2002)
    1200. S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. (PubMed id 12183632)9 Gu Z....Lipton S.A. (Science 2002)
    1201. Loss of sarcolemma nNOS in sarcoglycan-deficient muscle. (PubMed id 12409321)9 Crosbie R.H....Campbell K.P. (FASEB J. 2002)
    1202. Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors. (PubMed id 12512689)9 Channon K.M. and Guzik T.J. (J. Physiol. Pharmacol. 2002)
    1203. Tetrahydrobiopterin deficiency increases neuronal vulnerability to hypoxia. (PubMed id 12358762)9 Delgado-Esteban M....Medina J.M. (J. Neurochem. 2002)
    1204. S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase. (PubMed id 12370443)9 Leiper J....Vallance P. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    1205. Chemoarchitecture of GABAergic neurons in the ferret superior colliculus. (PubMed id 12355417)9 Behan M....Meredith M.A. (J. Comp. Neurol. 2002)
    1206. Effects of Ca(2+)-activated calmodulin on neuronal nitric oxide synthase reductase activity and binding of substrates: pH dependence of kinetic parameters. (PubMed id 11772018)9 Wolthers K.R. and Schimerlik M.I. (Biochemistry 2002)
    1207. Interactions between the isolated oxygenase and reductase domains of neuronal nitric-oxide synthase: assessing the role of calmodulin. (PubMed id 11884406)9 Rozhkova E.A....Shimizu T. (J. Biol. Chem. 2002)
    1208. Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock. (PubMed id 12089147)9 Craig D.H....Daff S. (J. Biol. Chem. 2002)
    1209. Perferryl complex of nitric oxide synthase: role in secondary free radical formation. (PubMed id 11853964)9 Porasuphatana S....Rosen G.M. (Biochim. Biophys. Acta 2002)
    1210. Therapeutic effect of neuronal nitric oxide synthase inhibitor (7-nitroindazole) against MPTP neurotoxicity in mice. (PubMed id 12322787)9 Muramatsu Y....Araki T. (Metab Brain Dis 2002)
    1211. Identification of a by-product of nitric oxide synthase activity in human acute brain injury with in vivo proton magnetic resonance spectroscopy. (PubMed id 11901005)9 Silberstein M....Opeskin K. (AJNR Am J Neuroradiol 2002)
    1212. Electrocardiographic findings in mdx mice: a cardiac phenotype of Duchenne muscular dystrophy. (PubMed id 12362417)9 Chu V....Hampton T.G. (amp 2002)
    1213. Selective inhibition of neuronal nitric oxide synthesis reduces hyperactivity and increases non-selective attention in the Naples High-Excitability rat. (PubMed id 11864728)9 Grammatikopoulos G....Sadile A.G. (Behav. Brain Res. 2002)
    1214. Localization of sepiapterin reductase in the human brain. (PubMed id 12414107)9 Ikemoto K....Nagatsu T. (Brain Res. 2002)
    1215. Distribution of nitric oxide synthase in normal and cirrhotic human liver. (PubMed id 12482944)9 McNaughton L....Radomski M.W. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    1216. Nitric oxide-cGMP-mediated vasoconstriction and effects of acetylcholine in the branchial circulation of the eel. (PubMed id 12020661)9 Pellegrino D....Tota B. (amp 2002)
    1217. Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide. (PubMed id 12358775)9 Ciani E....Contestabile A. (J. Neurochem. 2002)
    1218. Decreased nitric oxide- and axon reflex-mediated cutaneous vasodilation with age during local heating. (PubMed id 12381749)9 Minson C.T....Wilkins B.W. (J. Appl. Physiol. 2002)
    1219. Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes. (PubMed id 11997374)9 del RA-o L.A....Barroso J.B. (J. Exp. Bot. 2002)
    1220. The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis. (PubMed id 12437343)9 Li H....Poulos T.L. (Biochemistry 2002)
    1221. Anti-inflammatory effect of recombinant human superoxide dismutase in rats and mice and its mechanism. (PubMed id 11978194)9 Zhang Y....Li W.G. (Acta Pharmacol. Sin. 2002)
    1222. The effect of D-aspartate on luteinizing hormone-releasing hormone, alpha-melanocyte-stimulating hormone, GABA and dopamine release. (PubMed id 12488823)9 Pampillo M....Lasaga M. (Neuroreport 2002)
    1223. Placental imbalance of vasoactive factors does not affect pregnancy outcome in patients treated with Cyclosporine A after transplantation. (PubMed id 11920344)9 Di Paolo S....Gesualdo L. (Am. J. Kidney Dis. 2002)
    1224. The indices of endogenous oxidative and antioxidative processes in plasma from schizophrenic patients. The possible role of oxidant/antioxidant imbalance. (PubMed id 12369276)9 Akyol O....SavaA9 H.A. (amp 2002)
    1225. Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase. (PubMed id 12214661)9 Nishida C.R....Ortiz de Montellano P.R. (Drug Metab. Rev. 2002)
    1226. Tetrahydrobiopterin in nitric oxide synthesis: a novel biological role for pteridines. (PubMed id 12003347)9 Gorren A.C. and Mayer B. (Curr. Drug Metab. 2002)
    1227. [Early post-denervation depolarization: effect of NO, acetylcholine and glutamate on chloride transporter]. (PubMed id 12608108)9 Vyskocil F. (Cesk Fysiol 2002)
    1228. Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide. (PubMed id 11960777)9 Holian O....Attar B.M. (Am. J. Physiol. Gastrointest. Liver Physiol. 2002)
    1229. Neuronal and inducible nitric oxide synthase immunoreactivity following serotonin depletion. (PubMed id 12468035)9 Ramos A.J....Brusco A. (Brain Res. 2002)
    1230. A conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificity. (PubMed id 12359874)9 Adak S....Stuehr D.J. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    1231. Anthelmintic efficacy of Flemingia vestita: genistein-induced effect on the activity of nitric oxide synthase and nitric oxide in the trematode parasite, Fasciolopsis buski. (PubMed id 12243779)9 Kar P.K....Saha N. (Parasitol. Int. 2002)
    1232. Widespread changes in neurotransmitter expression and number of enteric neurons and interstitial cells of Cajal in lethal spotted mice: an explanation for persisting dysmotility after operation for Hirschsprung's disease? (PubMed id 12018900)9 Sandgren K....Ekblad E. (Dig. Dis. Sci. 2002)
    1233. A study on nitric oxide, beta-adrenergic receptors and antioxidant status in the polymorphonuclear leukocytes from the patients of depression. (PubMed id 12204316)9 Srivastava N....Dikshit M. (J Affect Disord 2002)
    1234. Reduced neuronal nitric oxide synthase (NOS1) antigen in sacral motor neurones in motor neurone disease. (PubMed id 12200626)9 Baxter R.G....Pullen A.H. (Acta Neuropathol. 2002)
    1235. Potentiation of 3-hydroxyglutarate neurotoxicity following induction of astrocytic iNOS in neonatal rat hippocampal cultures. (PubMed id 11422452)9 KAPlker S....Hoffmann G.F. (Eur. J. Neurosci. 2001)
    1236. Increased number of nitric oxide synthase immunoreactive Purkinje cells and dentate nucleus neurons in schizophrenia. (PubMed id 12118154)9 Bernstein H.G....Bogerts B. (J. Neurocytol. 2001)
    1237. Role of nitric oxide and cyclic GMP in glutamate-induced neuronal death. (PubMed id 14715472)9 Montoliu C....Felipo V. (Neurotox Res 2001)
    1238. Regulation of the properties of the heme-NO complexes in nitric-oxide synthase by hydrogen bonding to the proximal cysteine. (PubMed id 11479310)9 Couture M....Rousseau D.L. (J. Biol. Chem. 2001)
    1239. Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin. (PubMed id 11334852)9 Rosenblum W.I....Wei E.P. (Eur. J. Pharmacol. 2001)
    1240. Measurement of NO and NO synthase. (PubMed id 18428524)9 Weissman B.A. and Gross S.S. (Curr Protoc Neurosci 2001)
    1241. A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. (PubMed id 11299330)9 Almeida A. and BolaA+os J.P. (J. Neurochem. 2001)
    1242. L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. (PubMed id 11022034)9 Heller R....Werner E.R. (J. Biol. Chem. 2001)
    1243. A rapid and transient synthesis of nitric oxide (NO) by a constitutively expressed type II NO synthase in the guinea-pig suprachiasmatic nucleus. (PubMed id 11682457)9 Starkey S.J....Hagan R.M. (Br. J. Pharmacol. 2001)
    1244. A study on the prevention and treatment of myopia with nacre on chicks. (PubMed id 11428903)9 Xu H....Han X. (Pharmacol. Res. 2001)
    1245. Alpha(2)-adrenergic-mediated tubular NO production inhibits thick ascending limb chloride absorption. (PubMed id 11553515)9 Plato C.F. and Garvin J.L. (Am. J. Physiol. Renal Physiol. 2001)
    1246. Prevention of axial elongation in myopia by the trace element zinc. (PubMed id 11318236)9 Huibi X....Xiuxian H. (Biol Trace Elem Res 2001)
    1247. The role of nitric oxide in ocular surface diseases. (PubMed id 11811584)9 Park G.S....Kim J.C. (Korean J Ophthalmol 2001)
    1248. Inhibition of neuronal nitric oxide synthase by 6-nitrocatecholamines, putative reaction products of nitric oxide with catecholamines under oxidative stress conditions. (PubMed id 11336641)9 Palumbo A....d'Ischia M. (Biochem. J. 2001)
    1249. Nitric oxide: a novel link between synaptic and nonsynaptic transmission. (PubMed id 11250004)9 Kiss J.P. and Vizi E.S. (Trends Neurosci. 2001)
    1250. Nitric oxide synthase and cytochrome c oxidase changes in the tumoural and peritumoural cerebral cortex. (PubMed id 11685622)9 Garbossa D....Vercelli A. (Acta Neurochir (Wien) 2001)
    1251. NO vascular control in Duchenne muscular dystrophy. (PubMed id 11135610)9 Crosbie R.H. (Nat. Med. 2001)
    1252. Allergen-induced impairment of bronchoprotective nitric oxide synthesis in asthma. (PubMed id 11496234)9 Ricciardolo F.L....Sterk P.J. (J. Allergy Clin. Immunol. 2001)
    1253. Comparison of NADPH diaphorase activity in the brains of hamsters infected with scrapie strains 139H or 263K or with normal hamster brain homogenate. (PubMed id 11642749)9 Ye X....Carp R.I. (Histol. Histopathol. 2001)
    1254. Electrochemistry of pterin cofactors and inhibitors of nitric oxide synthase. (PubMed id 11292367)9 Gorren A.C....Mayer B. (Nitric Oxide 2001)
    1255. Tetrahydrobiopterin deficiencies without hyperphenylalaninemia: diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency. (PubMed id 11592814)9 Blau N....ThAPny B. (Mol. Genet. Metab. 2001)
    1256. Effect of cyclosporin A on nitric oxide production in cultured LLC-PK1 cells. (PubMed id 11256528)9 Lima R....Higa E.M. (Ren Fail 2001)
    1257. Important role of tetrahydrobiopterin in no complex formation and interdomain electron transfer in neuronal nitric-oxide synthase. (PubMed id 11302726)9 Noguchi T....Shimizu T. (Biochem. Biophys. Res. Commun. 2001)
    1258. Pterin interactions with distinct reductase activities of NO synthase. (PubMed id 11336634)9 Pantke M.M....Schmidt H.H. (Biochem. J. 2001)
    1259. Thiouracil antithyroid drugs as a new class of neuronal nitric oxide synthase inhibitors. (PubMed id 11401533)9 Palumbo A. and d'Ischia M. (Biochem. Biophys. Res. Commun. 2001)
    1260. Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress. (PubMed id 11738280)9 Shinozaki K....Kashiwagi A. (J. Am. Coll. Cardiol. 2001)
    1261. Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity. (PubMed id 11238718)9 Katsuki H....Akaike A. (J. Neurochem. 2001)
    1262. Neurotransmitter dysfunction in hepatic encephalopathy: new approaches and new findings. (PubMed id 11726089)9 Butterworth R.F. (Metab Brain Dis 2001)
    1263. Kinetics of CO and NO ligation with the Cys(331)--&gt;Ala mutant of neuronal nitric-oxide synthase. (PubMed id 11067850)9 Scheele J.S....Magde D. (J. Biol. Chem. 2001)
    1264. Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease. (PubMed id 11437988)9 Schneider J....Schemann M. (Neurogastroenterol. Motil. 2001)
    1265. Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study. (PubMed id 11488360)9 Narendran R....Grace J.J. (J Clin Psychiatry 2001)
    1266. Formation of a protonated trihydrobiopterin radical cation in the first reaction cycle of neuronal and endothelial nitric oxide synthase detected by electron paramagnetic resonance spectroscopy. (PubMed id 11293408)9 Schmidt P.P....Andersson K.K. (J. Biol. Inorg. Chem. 2001)
    1267. Children and adolescents with psychotic disorder not otherwise specified: a 2- to 8-year follow-up study. (PubMed id 11458307)9 Nicolson R....Rapoport J.L. (Compr Psychiatry 2001)
    1268. DRD4 exon 3 variants associated with delusional symptomatology in major psychoses: a study on 2,011 affected subjects. (PubMed id 11353451)9 Serretti A....Smeraldi E. (Am. J. Med. Genet. 2001)
    1269. Vascular endothelial dysfunction: does tetrahydrobiopterin play a role? (PubMed id 11514262)9 Katusic Z.S. (Am. J. Physiol. Heart Circ. Physiol. 2001)
    1270. The susceptibility of muscle cells to oxidative stress is independent of nitric oxide synthase expression. (PubMed id 11268022)9 Zhuang W....Rando T.A. (amp 2001)
    1271. Relatively selective neuronal nitric oxide synthase inhibition by 7-nitroindazole in monkey isolated cerebral arteries. (PubMed id 11448483)9 Ayajiki K....Toda N. (Eur. J. Pharmacol. 2001)
    1272. Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla. (PubMed id 11316492)9 Imbrogno S....Tota B. (J. Exp. Biol. 2001)
    1273. Bupropion sustained release as a smoking cessation treatment in remitted depressed patients maintained on treatment with selective serotonin reuptake inhibitor antidepressants. (PubMed id 11488359)9 Chengappa K.N....Levine J. (J Clin Psychiatry 2001)
    1274. Involvement of the perferryl complex of nitric oxide synthase in the catalysis of secondary free radical formation. (PubMed id 11287127)9 Porasuphatana S....Rosen G.M. (Biochim. Biophys. Acta 2001)
    1275. Evidence for the involvement of nitric oxide in the control of steroid secretion by the frog adrenal gland. (PubMed id 11457663)9 Cartier F....Delarue C. (J. Steroid Biochem. Mol. Biol. 2001)
    1276. Effect of isosorbide dinitrate on nitric oxide synthase under hypoxia. (PubMed id 11150917)9 Jiang H.B....Ichikawa Y. (Pharmacology 2001)
    1277. Iron overload, oxidative stress, and axonal dystrophy in brain disorders. (PubMed id 11551744)9 Chiueh C.C. (Pediatr. Neurol. 2001)
    1278. Role of nitric oxide in ethanol-induced up-regulation of muscarinic acetylcholine receptors in SH-SY5Y cells. (PubMed id 11505040)9 Caron M.H. and Alling C. (Alcohol. Clin. Exp. Res. 2001)
    1279. Cell-cycle arrest in TrkA-expressing NIH3T3 cells involves nitric oxide synthase. (PubMed id 11180409)9 Bulseco D.A....Ross A.H. (J. Cell. Biochem. 2001)
    1280. Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity. (PubMed id 11258969)9 Moali C....Mansuy D. (Chem. Res. Toxicol. 2001)
    1281. Nitric oxide and neurally mediated regulation of skin blood flow during local heating. (PubMed id 11568143)9 Minson C.T....Joyner M.J. (J. Appl. Physiol. 2001)
    1282. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. (PubMed id 11556547)9 Heneka M.T....Klockgether T. (J. Neuropathol. Exp. Neurol. 2001)
    1283. Inpatient diagnostic assessments: 1. Accuracy of structured vs. unstructured interviews. (PubMed id 11814544)9 Miller P.R....Brown F. (Psychiatry Res 2001)
    1284. Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis. (PubMed id 11573993)9 Anneser J.M....Borasio G.D. (Exp. Neurol. 2001)
    1285. Nitric oxide generation from hydroxylamine in the presence of neutrophils and in the cell-free system. (PubMed id 11552946)9 Klink M....SuA8owska Z. (APMIS 2001)
    1286. Glial-derived arginine, the nitric oxide precursor, protects neurons from NMDA-induced excitotoxicity. (PubMed id 11860470)9 Grima G....Do K.Q. (Eur. J. Neurosci. 2001)
    1287. Inhibition of neuronal nitric oxide synthase by N-phenacyl imidazoles. (PubMed id 11178934)9 Sorrenti V....Vanella A. (Nitric Oxide 2001)
    1288. Global assessment of functioning following assertive community treatment in Edmonton, Alberta: a longitudinal study. (PubMed id 11280083)9 Tibbo P....Wright E. (Can J Psychiatry 2001)
    1289. Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer. (PubMed id 11566494)9 Rajnakova A....Ngoi S. (Cancer Lett. 2001)
    1290. Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase. (PubMed id 11697043)9 Huang H....Silverman R.B. (J. Enzym. Inhib. 2001)
    1291. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. (PubMed id 11516769)9 Davidson C....Ellinwood E.H. (Brain Res. Brain Res. Rev. 2001)
    1292. The role of tetrahydrobiopterin in the activation of oxygen by nitric-oxide synthase. (PubMed id 11051565)9 Bec N....Lange R. (J. Inorg. Biochem. 2000)
    1293. Nitric oxide and neuronal and pancreatic beta cell death. (PubMed id 11090953)9 Adeghate E. and Parvez S.H. (Toxicology 2000)
    1294. Iron deficiency diminishes gallbladder neuronal nitric oxide synthase. (PubMed id 10781371)9 Swartz-Basile D.A....Pitt H.A. (J. Surg. Res. 2000)
    1295. 2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisation. (PubMed id 11094150)9 Palumbo A....Cioffi F.A. (FEBS Lett. 2000)
    1296. Discovery and development of neuronal nitric oxide synthase inhibitors. (PubMed id 10927171)9 Reif D.W....Macdonald J.E. (amp 2000)
    1297. [Expression of reactive oxygen-species related enzymes in endothelial cells stimulated with glycated lipoproteins]. (PubMed id 10810880)9 Sakairi K....Komoda T. (Rinsho Byori 2000)
    1298. [Clinical study of Astragalus injection plus ligustrazine in protecting myocardial ischemia reperfusion injury]. (PubMed id 11789206)9 Zhou S....Zhang W. (Zhongguo Zhong Xi Yi Jie He Za Zhi 2000)
    1299. Dissociation of the dystroglycan complex in caveolin-3-deficient limb girdle muscular dystrophy. (PubMed id 11001938)9 Herrmann R.... Voit T. (Hum. Mol. Genet. 2000)
    1300. One-electron reduction of quinones by the neuronal nitric-oxide synthase reductase domain. (PubMed id 10924903)9 Matsuda H....Iyanagi T. (Biochim. Biophys. Acta 2000)
    1301. Tumor necrosis factor alpha enhances the cytotoxicity induced by nitric oxide in cultured cerebral endothelial cells. (PubMed id 10755468)9 Zhu D.Y....Hua W.Y. (Life Sci. 2000)
    1302. Preconditioning regulation of bcl-2 and p66shc by human NOS1 enhances tolerance to oxidative stress. (PubMed id 11023998)9 Andoh T....Chiueh C.C. (FASEB J. 2000)
    1303. Endothelin inhibits thick ascending limb chloride flux via ET(B) receptor-mediated NO release. (PubMed id 10919853)9 Plato C.F....Garvin J.L. (Am. J. Physiol. Renal Physiol. 2000)
    1304. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. (PubMed id 11003138)9 Hah J.M....Silverman R.B. (amp 2000)
    1305. Pattern of distribution and co-localization of NOS and ATP in the myenteric plexus of human fetal stomach and intestine. (PubMed id 10683820)9 Belai A. and Burnstock G. (Neuroreport 2000)
    1306. Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide. (PubMed id 10698705)9 Kotsonis P....Schmidt H.H. (Biochem. J. 2000)
    1307. Nitric oxide modulates retinal ganglion cell axon arbor remodeling in vivo. (PubMed id 11018773)9 Cogen J. and Cohen-Cory S. (J. Neurobiol. 2000)
    1308. Superoxide production and reactive oxygen species signaling by endothelial nitric-oxide synthase. (PubMed id 10747895)9 Wang W....Danner R.L. (J. Biol. Chem. 2000)
    1309. Retinoic acid-mediated enhancement of the cholinergic/neuronal nitric oxide synthase phenotype of the medial septal SN56 clone: establishment of a nitric oxide-sensitive proapoptotic state. (PubMed id 10820202)9 Personett D....McKinney M. (J. Neurochem. 2000)
    1310. Lack of nitric oxide involvement in cholinergic modulation of ovine ciliary beat frequency. (PubMed id 11066025)9 Salathe M....Bookman R.J. (J Aerosol Med 2000)
    1311. Calcium-activated potassium channels and nitric oxide coregulate estrogen-induced vasodilation. (PubMed id 10899072)9 Rosenfeld C.R....Cox B.E. (Am. J. Physiol. Heart Circ. Physiol. 2000)
    1312. Dual regulatory effects of nitric oxide on plasminogen activator inhibitor type 1 expression in endothelial cells. (PubMed id 10672008)9 Swiatkowska M....Cierniewski C.S. (Eur. J. Biochem. 2000)
    1313. Distinct expression of splice variants of neuronal nitric oxide synthase in the human gastrointestinal tract. (PubMed id 10784584)9 Saur D....Allescher H.D. (Gastroenterology 2000)
    1314. The serum nitric oxide levels in patients with Duchenne muscular dystrophy. (PubMed id 10814901)9 GA1cA1yener K....SerdaroA9lu A. (amp 2000)
    1315. Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity. (PubMed id 11046152)9 Chang Y.W....Sorokin A. (Mol. Cell. Biol. 2000)
    1316. Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions. (PubMed id 10694400)9 Boggs S....Stuehr D.J. (Biochemistry 2000)
    1317. Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons. (PubMed id 10686080)9 Toborek M....Young B. (Exp. Neurol. 2000)
    1318. Gene expression of neuronal nitric oxide synthase and adrenomedullin in human neuroblastoma using real-time PCR. (PubMed id 11004664)9 DAPtsch J....Rascher W. (Int. J. Cancer 2000)
    1319. Mitochondria and calcium: from cell signalling to cell death. (PubMed id 11080251)9 Duchen M.R. (J. Physiol. (Lond.) 2000)
    1320. Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH. (PubMed id 10846172)9 Sagami I....Shimizu T. (J. Biol. Chem. 2000)
    1321. Production and interaction of oxygen and nitric oxide free radicals in PMA stimulated macrophages during the respiratory burst. (PubMed id 11140745)9 Li H....Zhao B. (Redox Rep. 2000)
    1322. NO increases permeability of cultured human cervical epithelia by cGMP-mediated increase in G-actin. (PubMed id 10794668)9 Gorodeski G.I. (Am. J. Physiol., Cell Physiol. 2000)
    1323. Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a. (PubMed id 10661494)9 LA1th H.J....Arendt T. (Brain Res. 2000)
    1324. Clozapine treatment in a population of adults with mental retardation. (PubMed id 10695641)9 Antonacci D.J. and de Groot C.M. (J Clin Psychiatry 2000)
    1325. Metalloporphyrin catalyzed oxidation of N-hydroxyguanidines: a biomimetic model for the H2O2-dependent activity of nitric oxide synthase. (PubMed id 10937746)9 Keseru G.M....Karancsi T. (amp 2000)
    1326. Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease. (PubMed id 10672847)9 Maier W....LA1scher T.F. (J. Cardiovasc. Pharmacol. 2000)
    1327. Role of paraquat in the uncoupling of nitric oxide synthase. (PubMed id 11113575)9 Margolis A.S....Rosen G.M. (Biochim. Biophys. Acta 2000)
    1328. Localization of the e-NOS enzyme in endothelial cells and odontoblasts of healthy human dental pulp. (PubMed id 11191645)9 Felaco M....Conti P. (Life Sci. 2000)
    1329. Nitric oxide decreases endothelial activation by rat experimental severe pancreatitis-associated ascitic fluids. (PubMed id 10766457)9 Masamune A....Toyota T. (Pancreas 2000)
    1330. Dopamine transporter and nitric oxide synthase in hypoxic-ischemic brain. (PubMed id 10738916)9 Meng S.Z....Takashima S. (Pediatr. Neurol. 2000)
    1331. Regulation of the GABA(A) receptor by nitric oxide in frog pituitary melanotrophs. (PubMed id 10965918)9 Castel H....Vaudry H. (Endocrinology 2000)
    1332. Expression of focal adhesion kinase (p125 FAK) and proline-rich tyrosine kinase 2 (PYK2/CAKb) in cerebral metastases, correlation with VEGF-R-, ecNOS III-labelling and morphometric data. (PubMed id 10928051)9 Ludwig H.C....Kolenda H. (Anticancer Res. 2000)
    1333. Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin. (PubMed id 10749677)9 Gorren A.C....Mayer B. (Biochem. J. 2000)
    1334. Formation of nNOS/PSD-95 PDZ dimer requires a preformed beta-finger structure from the nNOS PDZ domain. (PubMed id 11031113)9 Tochio H....Zhang M. (J. Mol. Biol. 2000)
    1335. Cytochrome P450 catalyzed nitric oxide synthesis: a theoretical study. (PubMed id 10698112)9 KeserA1 G.M....Balogh G.T. (amp 2000)
    1336. Prenatal exposure to a low concentration of carbon monoxide disrupts hippocampal long-term potentiation in rat offspring. (PubMed id 10900254)9 Mereu G....Cuomo V. (J. Pharmacol. Exp. Ther. 2000)
    1337. Reductive activation of mitomycin C by neuronal nitric oxide synthase. (PubMed id 10874132)9 Jiang H.B....Ichikawa Y. (Biochem. Pharmacol. 2000)
    1338. Ascorbic acid acts as an inhibitory transmitter in the hypothalamus to inhibit stimulated luteinizing hormone-releasing hormone release by scavenging nitric oxide. (PubMed id 10677552)9 Karanth S....McCann S.M. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    1339. Vagal ganglionic and nonadrenergic noncholinergic neurotransmission to the ferret lower oesophageal sphincter. (PubMed id 11269922)9 Smid S.D. and Blackshaw L.A. (amp 2000)
    1340. Low-temperature optical absorption spectra suggest a redox role for tetrahydrobiopterin in both steps of nitric oxide synthase catalysis. (PubMed id 10995244)9 Gorren A.C....Mayer B. (Biochemistry 2000)
    1341. [Reduced neuronal nitric oxide synthetase and c-protein kinase levels in Alzheimer's disease]. (PubMed id 10789135)9 Gargiulo L....Liras A. (Rev Neurol 2000)
    1342. Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95. (PubMed id 10623522)9 Tochio H....Zhang M. (J. Mol. Biol. 2000)
    1343. [Modulatory effects of 17beta-estradiol on the electrical activity of subfornical organ neurons]. (PubMed id 11941419)9 Wang H....He R.R. (Sheng Li Xue Bao 2000)
    1344. Depression in schizophrenia: nursing care as a generalized resistance resource. (PubMed id 11271136)9 Menzies V. (Issues Ment Health Nurs 2000)
    1345. Cholinergic nerves in human corpus cavernosum and spongiosum contain nitric oxide synthase and heme oxygenase. (PubMed id 10953170)9 Hedlund P....Andersson K.E. (J. Urol. 2000)
    1346. Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy. (PubMed id 11087833)9 Sander M....Victor R.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    1347. Clinical predictors of acute response with quetiapine in psychotic mood disorders. (PubMed id 10817103)9 Zarate C.A....Zapatel J. (J Clin Psychiatry 2000)
    1348. Role of nitric oxide and cyclic guanosine 3',5'-monophosphate in the estrogen regulation of cervical epithelial permeability. (PubMed id 10803574)9 Gorodeski G.I. (Endocrinology 2000)
    1349. Electron paramagnetic resonance spectroscopy with N-methyl-D-glucamine dithiocarbamate iron complexes distinguishes nitric oxide and nitroxyl anion in a redox-dependent manner: applications in identifying nitrogen monoxide products from nitric oxide synthase. (PubMed id 11053782)9 Xia Y....Zweier J.L. (amp 2000)
    1350. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. (PubMed id 10930440)9 Watkins C.C....Ferris C.D. (J. Clin. Invest. 2000)
    1351. Cytoplasmic dynein LC8 interacts with lyssavirus phosphoprotein. (PubMed id 11024152)9 Jacob Y....Tordo N. (J. Virol. 2000)
    1352. Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxide. (PubMed id 11072090)9 Zhang W.Y....Mori M. (Brain Res. Mol. Brain Res. 2000)
    1353. Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress. (PubMed id 10401604)9 Rego A.C....Oliveira C.R. (amp 1999)
    1354. NADPH-diaphorase histochemistry reveals an autonomic-like innervation in the postnatal hamster cochlea. (PubMed id 10441233)9 Morris J.C....Simmons D.D. (J. Comp. Neurol. 1999)
    1355. Geminate recombination of nitric oxide to endothelial nitric-oxide synthase and mechanistic implications. (PubMed id 10455137)9 NAcgrerie M....Martin J.L. (J. Biol. Chem. 1999)
    1356. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. (PubMed id 10690326)9 Leiper J. and Vallance P. (Cardiovasc. Res. 1999)
    1357. Stoichiometric arginine binding in the oxygenase domain of inducible nitric oxide synthase requires a single molecule of tetrahydrobiopterin per dimer. (PubMed id 10198214)9 Rafferty S.P....Malech H.L. (Biochem. Biophys. Res. Commun. 1999)
    1358. Negative symptoms of familial schizophrenia breed true in unstable (vs. stable) cerebral-ventricle pedigrees. (PubMed id 9988837)9 Filbey F.M....Garver D.L. (Schizophr. Res. 1999)
    1359. Neuronal NOS: gene structure, mRNA diversity, and functional relevance. (PubMed id 10223522)9 Wang Y....Marsden P.A. (Crit Rev Neurobiol 1999)
    1360. Inhibition of neuronal nitric oxide synthase by phosphatidylinositol 4,5-bisphosphate and phosphatidic acid. (PubMed id 10544274)9 Hori H....Nishino T. (J. Biochem. 1999)
    1361. Endogenous nitric oxide synthesis: biological functions and pathophysiology. (PubMed id 10630682)9 Bredt D.S. (Free Radic. Res. 1999)
    1362. Stopped-flow analysis of substrate binding to neuronal nitric oxide synthase. (PubMed id 10493814)9 Abu-Soud H.M....Stuehr D.J. (Biochemistry 1999)
    1363. Kalirin inhibition of inducible nitric-oxide synthase. (PubMed id 9873042)9 Ratovitski E.A....Lowenstein C.J. (J. Biol. Chem. 1999)
    1364. Heterogeneous basal expression of nitric oxide synthase and superoxide dismutase isoforms in mammalian heart : implications for mechanisms governing indirect and direct nitric oxide-related effects. (PubMed id 10506482)9 Brahmajothi M.V. and Campbell D.L. (Circ. Res. 1999)
    1365. Elevated prolactin in pediatric patients on typical and atypical antipsychotics. (PubMed id 10630453)9 Wudarsky M....Rapoport J.L. (J Child Adolesc Psychopharmacol 1999)
    1366. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. (PubMed id 10484661)9 Boucher J.L....Tenu J.P. (Cell. Mol. Life Sci. 1999)
    1367. Enzymatic function of nitric oxide synthases. (PubMed id 10690324)9 Andrew P.J. and Mayer B. (Cardiovasc. Res. 1999)
    1368. Endogenous nitric oxide inhibits chloride transport in the thick ascending limb. (PubMed id 9887091)9 Plato C.F....Garvin J.L. (Am. J. Physiol. 1999)
    1369. Nitric oxide and Drosophila development. (PubMed id 10556972)9 Enikolopov G....Kuzin B. (Cell Death Differ. 1999)
    1370. Post-traumatic migration and emergence of a novel cell line upon the ependymal surface of the third cerebral ventricle in the adult mammalian brain. (PubMed id 10521782)9 Scott D.E. (Anat. Rec. 1999)
    1371. Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic potentiation in hippocampal CA1 pyramidal neurons. (PubMed id 10436036)9 Ko G.Y. and Kelly P.T. (J. Neurosci. 1999)
    1372. Effects of CB(1) cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activity. (PubMed id 10518035)9 Hillard C.J....Kearn C.S. (FEBS Lett. 1999)
    1373. Decreasing estrogen in nonpregnant women lowers uterine myometrial type I nitric oxide synthase protein expression. (PubMed id 10411788)9 Weeks A.D....Figueroa J.P. (Am. J. Obstet. Gynecol. 1999)
    1374. Intranuclear inclusions in subtypes of striatal neurons in Huntington's disease transgenic mice. (PubMed id 10716229)9 Kosinski C.M....Schwarz M. (Neuroreport 1999)
    1375. Nitric oxide in the regulation of vasomotor tone in human skeletal muscle. (PubMed id 10362675)9 RAYdegran G. and Saltin B. (Am. J. Physiol. 1999)
    1376. Blockade by NS-7, a neuroprotective compound, of both L-type and P/Q-type Ca2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture. (PubMed id 10037505)9 Oka M....Kimura K. (J. Neurochem. 1999)
    1377. Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. (PubMed id 10503960)9 Inada H....Onaya T. (Life Sci. 1999)
    1378. Polymorphonuclear leukocyte nitrite content and antioxidant enzymes in Parkinson's disease patients. (PubMed id 10536916)9 Barthwal M.K....Dikshit M. (Acta Neurol. Scand. 1999)
    1379. Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO-. (PubMed id 10571239)9 Kim W.K....Lipton S.A. (Neuron 1999)
    1380. Mechanisms and sites of action of endothelins 1 and 2 on the opossum internal anal sphincter smooth muscle tone in vitro. (PubMed id 9862776)9 Chakder S. and Rattan S. (J. Pharmacol. Exp. Ther. 1999)
    1381. NADPH diaphorase histochemistry in the thoracic ganglia of locusts, crickets, and cockroaches: species differences and the impact of fixation. (PubMed id 10404407)9 Ott S.R. and Burrows M. (J. Comp. Neurol. 1999)
    1382. Tyrosine phosphorylation modulates the interaction of calmodulin with its target proteins. (PubMed id 10411641)9 Corti C....Carafoli E. (Eur. J. Biochem. 1999)
    1383. Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin. (PubMed id 10321973)9 Nagatsu T. and Ichinose H. (Mol. Neurobiol. 1999)
    1384. L-arginine increases UVA cytotoxicity in irradiated human keratinocyte cell line: potential role of nitric oxide. (PubMed id 10506585)9 Didier C....Richard M.J. (FASEB J. 1999)
    1385. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. (PubMed id 10330441)9 De Sanctis G.T....Drazen J.M. (J. Exp. Med. 1999)
    1386. Scintillation proximity assay to measure nitroarginine and tetrahydrobiopterin binding to heme domain of neuronal nitric oxide synthase. (PubMed id 9919559)9 Alderton W.K. and Lowe P.N. (Meth. Enzymol. 1999)
    1387. Gene transfer of vascular endothelial growth factor and endothelial nitric oxide synthase--implications for gene therapy in cardiovascular diseases. (PubMed id 10600037)9 Dulak J....DembiA8ska-KieA8 A. (Pol J Pharmacol 1999)
    1388. Cell death and oxidative stress in gliomas. (PubMed id 10476044)9 Tews D.S. (Neuropathol. Appl. Neurobiol. 1999)
    1389. Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation. (PubMed id 10074942)9 Fischmann T.O....Weber P.C. (Nat. Struct. Biol. 1999)
    1390. Imidazole-containing amino acids as selective inhibitors of nitric oxide synthases. (PubMed id 10530943)9 Lee Y....Silverman R.B. (amp 1999)
    1391. [The participation of the nontraditional neuromediator nitric oxide in the mechanisms of adaptation to extreme conditions]. (PubMed id 10420474)9 Fidelina O.V....Akmaev I.G. (Usp Fiziol Nauk 1999)
    1392. Structure of the PIN/LC8 dimer with a bound peptide. (PubMed id 10426949)9 Liang J.... Clardy J. (Nat. Struct. Biol. 1999)
    1393. Optic target regulation of NADPH-diaphorase by larval retinal axons in Drosophila. (PubMed id 10076863)9 Atkinson J. and Panni M.K. (Neurosci. Lett. 1999)
    1394. The stimulatory effects of Hofmeister ions on the activities of neuronal nitric-oxide synthase. Apparent substrate inhibition by l-arginine is overcome in the presence of protein-destabilizing agents. (PubMed id 10026150)9 Nishimura J.S....Masters B.S. (J. Biol. Chem. 1999)
    1395. Reduction of lung allograft ischemia/reperfusion injury by tetrahydrobiopterin coenzyme of NOS. (PubMed id 10083068)9 Hillinger S....Schmid R.A. (Transplant. Proc. 1999)
    1396. Anoxia/reoxygenation-induced tolerance with respect to polymorphonuclear leukocyte adhesion to cultured endothelial cells. A nuclear factor-kappaB-mediated phenomenon. (PubMed id 9915779)9 Cepinskas G....Kvietys P.R. (Circ. Res. 1999)
    1397. Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia. (PubMed id 10554878)9 Hicks C.A....O'Neill M.J. (Eur. J. Pharmacol. 1999)
    1398. Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha. (PubMed id 10533055)9 Downen M....Lee S.C. (Glia 1999)
    1399. Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: structure-activity relationship of antagonists of (6R)-5,6,7,8-tetrahydrobiopterin cofactor. (PubMed id 10514281)9 FrAPhlich L.G....Schmidt H.H. (J. Med. Chem. 1999)
    1400. Peroxynitrite mediated damage and lowered superoxide tolerance in primary cortical glial cultures after induction of the inducible isoform of NOS. (PubMed id 10498818)9 Noack H....Wolf G. (Glia 1999)
    1401. [Neuronal cell death in neurodegenerative disorders and oxidative stress]. (PubMed id 10377784)9 Shimohama S....Urushitani M. (Rinsho Shinkeigaku 1999)
    1402. The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca(2+)/calmodulin-dependent electron transfer. (PubMed id 10521442)9 Daff S....Shimizu T. (J. Biol. Chem. 1999)
    1403. Both neuronal NO synthase and nitric oxide are required for PC12 cell differentiation: a cGMP independent pathway. (PubMed id 9931481)9 Phung Y.T....Black S.M. (Brain Res. Mol. Brain Res. 1999)
    1404. Preganglionic endings from nucleus of Edinger-Westphal in pigeon ciliary ganglion contain neuronal nitric oxide synthase. (PubMed id 10580718)9 Cuthbertson S....Reiner A. (Vis. Neurosci. 1999)
    1405. Effects of nerve growth factor on nitric oxide-mediated neurotoxicity in primary cortical cultures. (PubMed id 11593517)9 Wu J. and Zhang J. (Chin. Med. J. 1999)
    1406. Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells. (PubMed id 10071909)9 MacPherson H....Ralston S.H. (Bone 1999)
    1407. Oxidative stress in brain ischemia. (PubMed id 9989455)9 Love S. (Brain Pathol. 1999)
    1408. Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity. (PubMed id 10359660)9 Kotsonis P....Schmidt H.H. (Biochem. J. 1999)
    1409. Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition. (PubMed id 10480900)9 Adak S....Stuehr D.J. (J. Biol. Chem. 1999)
    1410. Reactivity of tetrahydrobiopterin bound to nitric-oxide synthase. (PubMed id 10514451)9 Witteveen C.F....Kaufman S. (J. Biol. Chem. 1999)
    1411. Assessing the impact of cerebral injury after cardiac surgery: will determining the mechanism reduce this injury? (PubMed id 10391329)9 Baumgartner W.A....Johnston M.V. (Ann. Thorac. Surg. 1999)
    1412. The neuronal form of nitric oxide synthase is required for pattern formation by retinal afferents in the ferret lateral geniculate nucleus. (PubMed id 10446349)9 Cramer K.S. and Sur M. (Brain Res. Dev. Brain Res. 1999)
    1413. Degeneration of NO-synthesizing cerebrocortical neurons in transgenic mice expressing mutated superoxide dismutase is not due to elevated nitric oxide levels. (PubMed id 9878761)9 Aguila M.C. and Kuljis R.O. (Brain Res. 1999)
    1414. A comparative study of the effects of two nitric oxide synthase inhibitors and two nitric oxide donors on temporary focal cerebral ischemia in the Wistar rat. (PubMed id 9950505)9 Coert B.A....Meyer F.B. (J. Neurosurg. 1999)
    1415. Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation. (PubMed id 10531311)9 Ghafourifar P....Richter C. (J. Biol. Chem. 1999)
    1416. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. (PubMed id 10512739)9 Milstien S. and Katusic Z. (Biochem. Biophys. Res. Commun. 1999)
    1417. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. (PubMed id 10364559)9 Sattler R....Tymianski M. (Science 1999)
    1418. A mechanism of paraquat toxicity involving nitric oxide synthase. (PubMed id 10535996)9 Day B.J....Stamler J.S. (Proc. Natl. Acad. Sci. U.S.A. 1999)
    1419. A point mutation in a plant calmodulin is responsible for its inhibition of nitric-oxide synthase. (PubMed id 10593908)9 Kondo R....Johnson J.D. (J. Biol. Chem. 1999)
    1420. No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine. (PubMed id 10411000)9 Holm P....Moilanen E. (J. Leukoc. Biol. 1999)
    1421. Detection of urinary tract infections by reduction of nitroblue tetrazolium. (PubMed id 9767552)9 Smith S.D....Weiss R.M. (Kidney Int. 1998)
    1422. Enhancement of serum nitric oxide by Shichimotsu-koka-to (Kampo medicine). (PubMed id 9821814)9 Sakuma Z....Ogihara Y. (amp 1998)
    1423. Neuronal nitric oxide synthase and Hepatic Encephalopathy. (PubMed id 9804363)9 Rao V.L. and Butterworth R.F. (Metab Brain Dis 1998)
    1424. Steroid cell tumors of the ovary: clinical, ultrasonic, and MRI diagnosis--a case report. (PubMed id 9587754)9 Wang P.H....Ng H.T. (Eur J Radiol 1998)
    1425. The versatile and complex enzymology of nitric oxide synthase. (PubMed id 9721327)9 Gorren A.C. and Mayer B. (Biochemistry Mosc. 1998)
    1426. Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain. (PubMed id 9593932)9 DAcgA- R....Busija D.W. (Brain Res. Dev. Brain Res. 1998)
    1427. Assessment of nitric oxide production by measurement of [15N]citrulline enrichment in human plasma using high-performance liquid chromatography-mass spectrometry. (PubMed id 9512771)9 Lagerwerf F.M....Boer P. (Anal. Biochem. 1998)
    1428. Neuronal nitric oxide synthase inhibitor, 7-nitroindazole, delays motor dysfunction and spinal motoneuron degeneration in the wobbler mouse. (PubMed id 9804111)9 Ikeda K....Kinoshita M. (J. Neurol. Sci. 1998)
    1429. Aprotinin, the first competitive protein inhibitor of NOS activity. (PubMed id 9705869)9 Venturini G....Ascenzi P. (Biochem. Biophys. Res. Commun. 1998)
    1430. Inducible nitric oxide synthase (iNOS)-like immunoreactivity in argyrophilic, tau-positive astrocytes in progressive supranuclear palsy. (PubMed id 9560010)9 Komori T....Iwata M. (Acta Neuropathol. 1998)
    1431. Role of nitric oxide in kainic acid-induced elevation of cochlear compound action potential thresholds. (PubMed id 9840501)9 Johnson K.L....Pillsbury H.C. (Acta Otolaryngol. 1998)
    1432. Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures. (PubMed id 9893946)9 Nicoletti V.G....Stella A.M. (Biochimie 1998)
    1433. Human influenza viral infection in utero increases nNOS expression in hippocampi of neonatal mice. (PubMed id 9552178)9 Fatemi S.H....Kist D. (Synapse 1998)
    1434. Colchicine differentially induces the expressions of nitric oxide synthases in central and peripheral catecholaminergic neurons. (PubMed id 9514822)9 Vanhatalo S....Soinila S. (Exp. Neurol. 1998)
    1435. Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways. (PubMed id 9932430)9 Dawson T.M....Dawson V.L. (Prog. Brain Res. 1998)
    1436. Induction of tetrahydrobiopterin synthesis in human umbilical vein smooth muscle cells by inflammatory stimuli. (PubMed id 9541457)9 Walter R....Schoedon G. (Immunol. Lett. 1998)
    1437. Effects of selective inhibitors of neuronal nitric oxide synthase on carrageenan-induced mechanical and thermal hyperalgesia. (PubMed id 9680257)9 Handy R.L. and Moore P.K. (Neuropharmacology 1998)
    1438. [Effect of nitric oxide release on epileptiform discharge in CA1 area of hippocampal slices]. (PubMed id 11367745)9 Lu W....Cheng J.S. (Sheng Li Xue Bao 1998)
    1439. Molecular actions of a Mn(III)Porphyrin superoxide dismutase mimetic and peroxynitrite scavenger: reaction with nitric oxide and direct inhibition of NO synthase and soluble guanylyl cyclase. (PubMed id 9547373)9 Pfeiffer S....Mayer B. (Mol. Pharmacol. 1998)
    1440. Neuronal nitric oxide synthase, nNOS, is not linked to infantile hypertrophic pyloric stenosis in three families. (PubMed id 9660065)9 SAPderhAoll C. and NordenskjAPld A. (Clin. Genet. 1998)
    1441. Immunohistochemical examination of NOS and SOD in nasal mucosa. (PubMed id 10095869)9 Sawada T....Nagatsu I. (Acta Otolaryngol Suppl 1998)
    1442. Neuronal nitric oxide synthase is refractory to mechanism-based inactivation in GH3 pituitary cells. (PubMed id 9735160)9 Cooper G.R....Wolff D.J. (Arch. Biochem. Biophys. 1998)
    1443. On the selectivity of 7-nitroindazole as an inhibitor of neuronal nitric oxide synthase. (PubMed id 9786021)9 Reiner A. and Zagvazdin Y. (Trends Pharmacol. Sci. 1998)
    1444. Effects of transition metals on nitric oxide synthase catalysis. (PubMed id 9736696)9 Perry J.M. and Marletta M.A. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    1445. Inducible nitric-oxide synthase generates superoxide from the reductase domain. (PubMed id 9712892)9 Xia Y....Zweier J.L. (J. Biol. Chem. 1998)
    1446. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. (PubMed id 9748253)9 Xia Y....Zweier J.L. (J. Biol. Chem. 1998)
    1447. Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo. (PubMed id 9437024)9 KlAPcker N....BAohr M. (J. Neurosci. 1998)
    1448. The marginal nuclei of the spinal cord in turtles: neuron assemblies in which gamma-aminobutyric acid and nitric oxide synthase are colocalized. (PubMed id 9772120)9 FernA!ndez A....Trujillo-CenA^z O. (Exp Brain Res 1998)
    1449. How selective is 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase? (PubMed id 9495447)9 Zagvazdin Y....Benter I.F. (Anesth. Analg. 1998)
    1450. The lectin-binding sites for peanut agglutinin in invasive breast ductal carcinomas and their metastasis. (PubMed id 9793958)9 Melato M....Jonjic N. (Pathol. Res. Pract. 1998)
    1451. Mini- and full-length dystrophin gene transfer induces the recovery of nitric oxide synthase at the sarcolemma of mdx4cv skeletal muscle fibers. (PubMed id 9536265)9 Decrouy A....Jasmin B.J. (Gene Ther. 1998)
    1452. Nitric oxide synthase in the thoracic ganglia of the locust: distribution in the neuropiles and morphology of neurones. (PubMed id 9603374)9 Ott S.R. and Burrows M. (J. Comp. Neurol. 1998)
    1453. [Nitric oxide, L-arginine and the kidney. Experimental studies of new therapy approaches]. (PubMed id 9505074)9 Ketteler M....Distler A. (Med. Klin. (Munich) 1998)
    1454. Dynamic modulation of cerebral cortex synaptic function by nitric oxide. (PubMed id 9932442)9 Kara P. and Friedlander M.J. (Prog. Brain Res. 1998)
    1455. Nitric oxide in cerebral ischemic neurodegeneration and excitotoxicity. (PubMed id 9847056)9 Strijbos P.J. (Crit Rev Neurobiol 1998)
    1456. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. (PubMed id 9689061)9 VA!squez-Vivar J....Pritchard K.A. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    1457. Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase. (PubMed id 9651169)9 Cowart M....Kerwin J.F. (J. Med. Chem. 1998)
    1458. The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases. (PubMed id 9688579)9 Hemmens B....Mayer B. (FEBS Lett. 1998)
    1459. Modulation of basal and postischemic leukocyte-endothelial adherence by nitric oxide. (PubMed id 9660399)9 Gidday J.M....Gonzales E.R. ( a journal of cerebral circulation 1998)
    1460. The subcellular distribution of nitric oxide synthase relative to the NR1 subunit of NMDA receptors in the cerebral cortex. (PubMed id 9932436)9 Aoki C....Lubin M. (Prog. Brain Res. 1998)
    1461. [Influence of NMDA receptor stimulation in brain cortex and hippocampus on NO dependent cGMP synthase. Effect of ischemia on NO related biochemical processes during recirculation]. (PubMed id 9770692)9 Chalimoniuk M....Strosznajder J. (Neurol. Neurochir. Pol. 1998)
    1462. NMDA receptor-dependent nitric oxide and cGMP synthesis in brain hemispheres and cerebellum during reperfusion after transient forebrain ischemia in gerbils: effect of 7-Nitroindazole. (PubMed id 9843159)9 Chalimoniuk M. and Strosznajder J. (J. Neurosci. Res. 1998)
    1463. Isoform-specific effects of salts on nitric oxide synthase activity. (PubMed id 9748616)9 Schrammel A....Mayer B. (Biochim. Biophys. Acta 1998)
    1464. Nitric oxide in the stress axis. (PubMed id 9810515)9 LA^pez-Figueroa M.O....Watson S.J. (Histol. Histopathol. 1998)
    1465. Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. (PubMed id 9875848)9 Raman C.S....Poulos T.L. (Cell 1998)
    1466. HMN-1180, a small molecule inhibitor of neuronal nitric oxide synthase. (PubMed id 9864293)9 Nishio M....Hidaka H. (J. Pharmacol. Exp. Ther. 1998)
    1467. A genome-wide search for schizophrenia susceptibility genes. (PubMed id 9754621)9 Shaw S.H....DeLisi L.E. (Am. J. Med. Genet. 1998)
    1468. Colocalization of tumor necrosis factor-alpha and nitric oxide-synthase immunoreactivity in mast cell granules of nasal mucosa. (PubMed id 9810496)9 Bacci S....Borghi-Cirri M.B. (Histol. Histopathol. 1998)
    1469. Major glutamatergic projection from subplate into visual cortex during development. (PubMed id 9703030)9 Finney E.M....Shatz C.J. (J. Comp. Neurol. 1998)
    1470. Cell death and oxidative damage in inflammatory myopathies. (PubMed id 9646833)9 Tews D.S. and Goebel H.H. (Clin. Immunol. Immunopathol. 1998)
    1471. Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine. (PubMed id 9671515)9 Moali C....Mansuy D. (Biochemistry 1998)
    1472. Retinoic acid-induced differentiation in a human neuroblastoma cell line is associated with an increase in nitric oxide synthesis. (PubMed id 9397160)9 Ghigo D....Bosia A. (J. Cell. Physiol. 1998)
    1473. Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells. (PubMed id 9458819)9 Chen L....Harris D.C. (Am. J. Physiol. 1998)
    1474. Methotrexate inhibition of inducible nitric oxide synthase in murine lung epithelial cells in vitro. (PubMed id 9618390)9 Robbins R.A....Milligan S.A. (Am. J. Respir. Cell Mol. Biol. 1998)
    1475. mdx muscle pathology is independent of nNOS perturbation. (PubMed id 9536086)9 Crosbie R.H....Campbell K.P. (Hum. Mol. Genet. 1998)
    1476. Skeletal muscle blood flow in humans and its regulation during exercise. (PubMed id 9578388)9 Saltin B....Roach R.C. (Acta Physiol. Scand. 1998)
    1477. Neuronal nitric-oxide synthase interaction with calmodulin-troponin C chimeras. (PubMed id 9488666)9 Gachhui R....Stuehr D.J. (J. Biol. Chem. 1998)
    1478. Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase. (PubMed id 9425051)9 Presta A....Stuehr D.J. (Biochemistry 1998)
    1479. Evidence for nitric oxide mediated effects on islet hormone secretory phospholipase C signal transduction mechanisms. (PubMed id 9877233)9 Akesson B. and Lundquist I. (Biosci. Rep. 1998)
    1480. Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets. (PubMed id 9813142)9 Tsuura Y....Seino Y. (Biochem. Biophys. Res. Commun. 1998)
    1481. The positive trophic effects of testosterone on neuronal nitric oxide synthase (nNOS) expression. (PubMed id 9432149)9 Seftel A.D. (J. Androl. 1997)
    1482. The human immunodeficiency virus type 1 (HIV-1) glycoprotein gp120 reduces the expression of neuronal nitric oxide synthase in the hippocampus but not in the cerebral cortex and medial septal nucleus of rat. (PubMed id 9086460)9 Bagetta G....NisticA^ G. (Neurosci. Lett. 1997)
    1483. Expression of endothelial nitric oxide synthase in human eccrine clear cells. (PubMed id 9155960)9 Shimizu Y....Ueda H. (Br. J. Dermatol. 1997)
    1484. Anticipation in schizophrenia: biology or bias? (PubMed id 9184310)9 Johnson J.E....Kaufmann C.A. (Am. J. Med. Genet. 1997)
    1485. Substrate and substrate analog binding to endothelial nitric oxide synthase: electron paramagnetic resonance as an isoform-specific probe of the binding mode of substrate analogs. (PubMed id 9305973)9 Salerno J.C....Masters B.S. (Biochemistry 1997)
    1486. Direct measurement of nitric oxide generation from nitric oxide synthase. (PubMed id 9356514)9 Xia Y. and Zweier J.L. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    1487. Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis. (PubMed id 9175139)9 Abe K....Itoyama Y. (Neurol. Res. 1997)
    1488. Tetrahydrobiopterin in the treatment of infantile hypertrophic pyloric stenosis. (PubMed id 9367805)9 Braegger C.P....Blau N. (Biochem. Mol. Med. 1997)
    1489. Involvement of nitric oxide in the interferon-gamma-induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures. (PubMed id 9202399)9 Vankelecom H....Denef C. (Mol. Cell. Endocrinol. 1997)
    1490. Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. (PubMed id 9168825)9 Kosinski C.M....Standaert D.G. (Exp. Neurol. 1997)
    1491. Effects of a nitric oxide synthase inhibitor on NMDA receptor function in organotypic hippocampal cultures. (PubMed id 9372233)9 Musleh W....Baudry M. (Brain Res. 1997)
    1492. Thiols and neuronal nitric oxide synthase: complex formation, competitive inhibition, and enzyme stabilization. (PubMed id 9100033)9 Gorren A.C....Mayer B. (Biochemistry 1997)
    1493. PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences. (PubMed id 9094134)9 Stricker N.L....Li M. (Nat. Biotechnol. 1997)
    1494. Differential effects of hyperoxia on the inducible and constitutive isoforms of nitric oxide synthase in the lung. (PubMed id 9165669)9 Arkovitz M.S....WispAc J.R. (Shock 1997)
    1495. Distribution of nitric oxide synthase implies a regulation of circulation, smooth muscle tone, and secretory function in the human prostate by nitric oxide. (PubMed id 9294619)9 Bloch W....Addicks K. (Prostate 1997)
    1496. Altered messenger RNA expression of the neuronal nitric oxide synthase gene in infantile hypertrophic pyloric stenosis. (PubMed id 9354728)9 Kusafuka T. and Puri P. (Pediatr. Surg. Int. 1997)
    1497. Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions. (PubMed id 9313890)9 Smith T.S. and Bennett J.P. (Brain Res. 1997)
    1498. Competitive inhibition of nitric oxide synthase by p-aminobenzamidine, a serine proteinase inhibitor. (PubMed id 9125158)9 Venturini G....Ascenzi P. (Biochem. Biophys. Res. Commun. 1997)
    1499. Neural roles of immunophilins and their ligands. (PubMed id 9396011)9 Sabatini D.M....Snyder S.H. (Mol. Neurobiol. 1997)
    1500. Effect of L-arginine and NG-nitro-L-arginine on delayed neuronal death in the gerbil hippocampus. (PubMed id 9263225)9 Nakagomi T....Tamura A. (Neurol. Res. 1997)
    1501. Nitrous oxide synthase expression in placenta of preeclampsia. (PubMed id 9443092)9 Lee C.N....Cho S.H. (J. Korean Med. Sci. 1997)
    1502. Structure-function aspects in the nitric oxide synthases. (PubMed id 9131257)9 Stuehr D.J. (Annu. Rev. Pharmacol. Toxicol. 1997)
    1503. PDZ domains: targeting signalling molecules to sub-membranous sites. (PubMed id 9204764)9 Ponting C.P....Blake D.J. (Bioessays 1997)
    1504. Nitric oxide is involved in the genesis of pulsatile LHRH secretion from immortalized LHRH neurons. (PubMed id 9355031)9 LA^pez F.J....Negro-Vilar A. (J. Neuroendocrinol. 1997)
    1505. Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters. (PubMed id 9288162)9 Silverman R.B....Martasek P. (J. Med. Chem. 1997)
    1506. The medial preoptic nucleus of the hypothalamus modulates activity of nitric oxide sensitive neurons in the midbrain periaqueductal gray. (PubMed id 9313893)9 Hall C.W. and Behbehani M.M. (Brain Res. 1997)
    1507. Activation and dimerization of type III nitric oxide synthase by submicromolar concentrations of tetrahydrobiopterin in microsomal preparations from human primordial placenta. (PubMed id 9089781)9 TA^th M....Sahin-TA^th M. (Placenta 1997)
    1508. Interactions between substrate analogues and heme ligands in nitric oxide synthase. (PubMed id 9109669)9 Wang J....Rousseau D.L. (Biochemistry 1997)
    1509. Nitric oxide and nitric oxide synthase: biology, pathology, localization. (PubMed id 9046060)9 Wolf G. (Histol. Histopathol. 1997)
    1510. Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen. (PubMed id 9464453)9 Renodon A....Mansuy D. (Biochem. Pharmacol. 1997)
    1511. Induction of guanosine triphosphate-cyclohydrolase by follicle-stimulating hormone enhances interleukin-1 beta-stimulated nitric oxide synthase activity in granulosa cells. (PubMed id 8977400)9 Tabraue C....Ruiz de Galarreta C.M. (Endocrinology 1997)
    1512. Bromocriptine is a strong inhibitor of brain nitric oxide synthase: possible consequences for the origin of its therapeutic effects. (PubMed id 9109381)9 Renodon A....Mansuy D. (FEBS Lett. 1997)
    1513. The distribution and co-localization of nitric oxide synthase and vasoactive intestinal polypeptide in nerves of the colons with Hirschsprung's disease. (PubMed id 9037316)9 Guo R....Masumoto K. (Virchows Arch. 1997)
    1514. [Glomerular hemodynamics in the isolated and perfused kidney. Effect of the inhibition of nitric oxide synthase]. (PubMed id 9410792)9 Gabbai F.B....Khang S. (Gac Med Mex 1997)
    1515. Identification of a novel repressive element that contributes to neuron-specific gene expression. (PubMed id 9315881)9 Weber J.R. and Skene J.H. (J. Neurosci. 1997)
    1516. Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. (PubMed id 9409218)9 Wilcox J.N....Marsden P.A. (Arterioscler. Thromb. Vasc. Biol. 1997)
    1517. The ferrous-dioxy complex of neuronal nitric oxide synthase. Divergent effects of L-arginine and tetrahydrobiopterin on its stability. (PubMed id 9211873)9 Abu-Soud H.M....Stuehr D.J. (J. Biol. Chem. 1997)
    1518. Proliferating cell nuclear antigen and heat shock protein 70 immunolocalization in invasive ductal breast cancer not otherwise specified. (PubMed id 9065598)9 Lazaris A.C.h....Golematis B.C.h. (Breast Cancer Res. Treat. 1997)
    1519. Innervation of extraocular pulley smooth muscle in monkeys and humans. (PubMed id 9286266)9 Demer J.L....Micevych P. (amp 1997)
    1520. Hypoxic and ischemic disorders of infants and children. Lecture for 38th meeting of Japanese Society of Child Neurology, Tokyo, Japan, July 1996. (PubMed id 9187471)9 Johnston M.V. (amp 1997)
    1521. Altered mRNA expression of the neuronal nitric oxide synthase gene in Hirschsprung's disease. (PubMed id 9247233)9 Kusafuka T. and Puri P. (J. Pediatr. Surg. 1997)
    1522. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. (PubMed id 9115257)9 Takeuchi M....Takai Y. (J. Biol. Chem. 1997)
    1523. The neurochemical coding and projections of circular muscle motor neurons in the human colon. (PubMed id 9394731)9 Porter A.J....Costa M. (Gastroenterology 1997)
    1524. mRNA and protein expression of nitric oxide synthase and adrenoceptor alpha 1 in young and old rat penile tissues. (PubMed id 9284206)9 Dahiya R....Lue T.F. (Br J Urol 1997)
    1525. Islet constitutive nitric oxide synthase: biochemical determination and regulatory function. (PubMed id 8764145)9 Salehi A....Lundquist I. (Am. J. Physiol. 1996)
    1526. Characterization of C415 mutants of neuronal nitric oxide synthase. (PubMed id 8672477)9 Richards M.K....Marletta M.A. (Biochemistry 1996)
    1527. GABA and nitric oxide synthase immunoreactivities are colocalized in a subset of inhibitory motor neurons of the guinea-pig small intestine. (PubMed id 8601294)9 Williamson S....Furness J.B. (Cell Tissue Res. 1996)
    1528. Decreased neuronal nitric oxide synthase messenger RNA and somatostatin messenger RNA in the striatum of Huntington's disease. (PubMed id 8735228)9 Norris P.J....Emson P.C. (Neuroscience 1996)
    1529. No .NO from NO synthase. (PubMed id 8962079)9 Schmidt H.H....Feelisch M. (Proc. Natl. Acad. Sci. U.S.A. 1996)
    1530. Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase. (PubMed id 8955056)9 Raber J....Mucke L. (Virology 1996)
    1531. Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered nitric oxide synthase inhibitors. (PubMed id 8880855)9 Hao J.X. and Xu X.J. (Pain 1996)
    1532. Nitric oxide neurotoxicity. (PubMed id 8811421)9 Dawson V.L. and Dawson T.M. (J. Chem. Neuroanat. 1996)
    1533. A comparison of cognitive profiles in schizophrenia and other psychiatric disorders. (PubMed id 8771446)9 Mitrushina M....Blumenfeld A. (J Clin Psychol 1996)
    1534. Inhibition of nitric oxide synthase does not prevent ocular dominance plasticity in kitten visual cortex. (PubMed id 8842009)9 Ruthazer E.S....Stryker M.P. (J. Physiol. (Lond.) 1996)
    1535. [The detection and clinical significance of nitric oxide synthetase activity in placenta tissue]. (PubMed id 9275412)9 Chen D. and Zheng M. (Zhonghua Fu Chan Ke Za Zhi 1996)
    1536. Glutamate receptors mediate dynamic regulation of nitric oxide synthase expression in cerebellar granule cells. (PubMed id 8778295)9 Baader S.L. and Schilling K. (J. Neurosci. 1996)
    1537. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. (PubMed id 8799551)9 Salvemini D....Currie M.G. (Br. J. Pharmacol. 1996)
    1538. Sleep and nitric oxide: effects of 7-nitro indazole, inhibitor of brain nitric oxide synthase. (PubMed id 8773777)9 Dzoljic M.R....van Leeuwen R. (Brain Res. 1996)
    1539. Inhibition of constitutive nitric oxide synthase by benexate. (PubMed id 8809208)9 Arimoto T....Kumagai Y. (Life Sci. 1996)
    1540. Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. (PubMed id 8643490)9 Li X.J....Ross C.A. (Proc. Natl. Acad. Sci. U.S.A. 1996)
    1541. Hyperpolarization and inhibition of contraction mediated by nitric oxide released from enteric inhibitory neurones in guinea-pig taenia coli. (PubMed id 8733575)9 Ward S.M....Westfall D.P. (Br. J. Pharmacol. 1996)
    1542. Autoradiographic localization of nitric oxide synthase binding sites in normal and diabetic rat corpus cavernosum. (PubMed id 8977077)9 Sullivan M.E....Morgan R.J. (Eur. Urol. 1996)
    1543. Constitutive nitric oxide synthase is present in normal human keratinocytes. (PubMed id 8648171)