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Aliases for NOP9 Gene

Aliases for NOP9 Gene

  • NOP9 Nucleolar Protein 2 3
  • C14orf21 3 4
  • Pumilio Domain-Containing Protein C14orf21 3
  • NOP9 Nucleolar Protein Homolog (Yeast) 2
  • Chromosome 14 Open Reading Frame 21 2
  • NOP9 Nucleolar Protein Homolog 3
  • Nucleolar Protein 9 3
  • KIAA2021 4

External Ids for NOP9 Gene

Previous Symbols for NOP9 Gene

  • C14orf21

Summaries for NOP9 Gene

GeneCards Summary for NOP9 Gene

NOP9 (NOP9 Nucleolar Protein) is a Protein Coding gene. GO annotations related to this gene include RNA binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOP9 Gene

Genomics for NOP9 Gene

Genomic Location for NOP9 Gene

Start:
24,299,854 bp from pter
End:
24,309,126 bp from pter
Size:
9,273 bases
Orientation:
Plus strand

Genomic View for NOP9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NOP9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NOP9 Gene

No data available for Regulatory Elements for NOP9 Gene

Proteins for NOP9 Gene

  • Protein details for NOP9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86U38-NOP9_HUMAN
    Recommended name:
    Nucleolar protein 9
    Protein Accession:
    Q86U38
    Secondary Accessions:
    • A8MY76
    • Q8IVF0
    • Q8TBS6

    Protein attributes for NOP9 Gene

    Size:
    636 amino acids
    Molecular mass:
    69438 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC23117.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for NOP9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NOP9 Gene

Proteomics data for NOP9 Gene at MOPED

Post-translational modifications for NOP9 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys120 and Lys611

Other Protein References for NOP9 Gene

No data available for DME Specific Peptides for NOP9 Gene

Domains for NOP9 Gene

Protein Domains for NOP9 Gene

UniProtKB/Swiss-Prot:

NOP9_HUMAN
Family:
  • Belongs to the NOP9 family.:
    • Q86U38
Similarity:
  • Contains 6 pumilio repeats.:
    • Q86U38
genes like me logo Genes that share domains with NOP9: view

No data available for Gene Families for NOP9 Gene

Function for NOP9 Gene

Gene Ontology (GO) - Molecular Function for NOP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function --
GO:0003723 RNA binding --
GO:0005488 binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with NOP9: view

Phenotypes for NOP9 Gene

genes like me logo Genes that share phenotypes with NOP9: view

miRNA for NOP9 Gene

miRTarBase miRNAs that target NOP9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for NOP9 Gene

Localization for NOP9 Gene

Gene Ontology (GO) - Cellular Components for NOP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with NOP9: view

Pathways for NOP9 Gene

SuperPathways for NOP9 Gene

No Data Available

Interacting Proteins for NOP9 Gene

Gene Ontology (GO) - Biological Process for NOP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with NOP9: view

No data available for Pathways by source for NOP9 Gene

Transcripts for NOP9 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for NOP9 Gene

No ASD Table

Relevant External Links for NOP9 Gene

GeneLoc Exon Structure for
NOP9
ECgene alternative splicing isoforms for
NOP9

Expression for NOP9 Gene

mRNA expression in normal human tissues for NOP9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NOP9 Gene

genes like me logo Genes that share expressions with NOP9: view

Orthologs for NOP9 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NOP9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NOP9 36
  • 99.37 (n)
  • 99.05 (a)
NOP9 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C10H14orf21 36
  • 88.05 (n)
  • 88.68 (a)
C10H14orf21 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C14ORF21 37
  • 86 (a)
OneToOne
NOP9 36
  • 87.12 (n)
  • 86.28 (a)
mouse
(Mus musculus)
Mammalia Nop9 36
  • 83.02 (n)
  • 82.08 (a)
Nop9 16
Nop9 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NOP9 37
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nop9 36
  • 83.49 (n)
  • 82.65 (a)
chicken
(Gallus gallus)
Aves LOC101750118 36
  • 51.39 (n)
  • 42.19 (a)
NOP9 37
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NOP9 37
  • 39 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC69156 36
tropical clawed frog
(Silurana tropicalis)
Amphibia nop9 36
  • 56.81 (n)
  • 50.09 (a)
Str.6747 36
zebrafish
(Danio rerio)
Actinopterygii AL954696.1 37
  • 35 (a)
OneToOne
LOC100332577 36
  • 49.28 (n)
  • 37.05 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011440 36
  • 42.73 (n)
  • 28.96 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11123 36
  • 42.71 (n)
  • 32.16 (a)
CG11123 37
  • 23 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ACR046W 36
  • 38.59 (n)
  • 22.51 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NOP9 36
  • 38.05 (n)
  • 24.15 (a)
NOP9 37
  • 19 (a)
OneToOne
NOP9 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E13685g 36
  • 38.01 (n)
  • 25.9 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons PUM23 36
  • 39.14 (n)
  • 26.52 (a)
rice
(Oryza sativa)
Liliopsida Os10g0390100 36
  • 39.88 (n)
  • 28.52 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes nop9 36
  • 36.9 (n)
  • 23.31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 29 (a)
OneToOne
Species with no ortholog for NOP9:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NOP9 Gene

ENSEMBL:
Gene Tree for NOP9 (if available)
TreeFam:
Gene Tree for NOP9 (if available)

Paralogs for NOP9 Gene

Selected SIMAP similar genes for NOP9 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with NOP9: view

No data available for Paralogs for NOP9 Gene

Variants for NOP9 Gene

Sequence variations from dbSNP and Humsavar for NOP9 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs941506 -- 24,302,637(-) CCAGT(C/T)TCTTG intron-variant
rs2144494 -- 24,304,181(-) TGGGC(A/G)AGGGA synonymous-codon, reference
rs3052629 -- 24,303,402(+) ttttt(-/TT)gagac intron-variant
rs4247000 -- 24,301,931(+) TTTTG(A/G)GAAAG intron-variant
rs4247001 -- 24,302,050(+) GCTCA(C/T)CTCTG synonymous-codon, reference

Relevant External Links for NOP9 Gene

HapMap Linkage Disequilibrium report
NOP9

No data available for Structural Variations from Database of Genomic Variants (DGV) for NOP9 Gene

Disorders for NOP9 Gene

No disorders were found for NOP9 Gene.

No data available for UniProtKB/Swiss-Prot for NOP9 Gene

Publications for NOP9 Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Specific and modular binding code for cytosine recognition in Pumilio/FBF (PUF) RNA-binding domains. (PMID: 21653694) Dong S. … Wang Z. (J. Biol. Chem. 2011) 2 3
  4. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  5. Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. (PMID: 22174317) Naji S. … Gerace L. (Mol. Cell Proteomics 2012) 3

Products for NOP9 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate NOP9
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for NOP9
    • Block miRNA regulation of NOP9 using miScript Target Protectors

    Sources for NOP9 Gene

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