Aliases for NOP58 Gene
External Ids for NOP58 Gene
Previous GeneCards Identifiers for NOP58 Gene
The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs. [provided by RefSeq, Nov 2015]
GeneCards Summary for NOP58 Gene
NOP58 (NOP58 Ribonucleoprotein) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and rRNA processing in the nucleus and cytosol. GO annotations related to this gene include poly(A) RNA binding and snoRNA binding.
UniProtKB/Swiss-Prot for NOP58 Gene
Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs.