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NOP16 Gene

protein-coding   GIFtS: 43
GCID: GC05M175810

NOP16 Nucleolar Protein

(Previous names: nucleolar protein 16 homolog (yeast), NOP16 nucleolar protein...)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NOP16 Nucleolar Protein1 2     HSPC1852
HBV Pre-S2 Trans-Regulated Protein 31 2 3     NOP16 Nucleolar Protein Homolog2
Hypothetical Protein HSPC1111 2     Nucleolar Protein 162
HSPC1112 5     Nucleolar Protein 16 Homolog2
NOP16 Nucleolar Protein Homolog (Yeast)1     NOP155
Nucleolar Protein 16 Homolog (Yeast)1     

External Ids:    HGNC: 269341   Entrez Gene: 514912   Ensembl: ENSG000000481627   OMIM: 6128615   UniProtKB: Q9Y3C13   

Export aliases for NOP16 gene to outside databases

Previous GC identifers: GC05M175744 GC05M170735


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NOP16 Gene:
NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression
is associated with poor patient survival (Butt et al., 2008).(supplied by OMIM, Jun 2009)

GeneCards Summary for NOP16 Gene:
NOP16 (NOP16 nucleolar protein) is a protein-coding gene. Diseases associated with NOP16 include breast cancer.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the NOP16 gene promoter:
         AP-2rep   Tal-1   CUTL1   E47   GATA-1   GATA-2   Egr-2   E2F-1   E2F   COMP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NOP16 promoter sequence
   Search Chromatin IP Primers for NOP16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NOP16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.2   Ensembl cytogenetic band:  5q35.2   HGNC cytogenetic band: 5q35.2

NOP16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOP16 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M175810:  view genomic region     (about GC identifiers)

Start:
175,810,949 bp from pter      End:
175,815,976 bp from pter
Size:
5,028 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NOP16_HUMAN, Q9Y3C1 (See protein sequence)
Recommended Name: Nucleolar protein 16  
Size: 178 amino acids; 21188 Da
Sequence caution: Sequence=AAH19331.1; Type=Frameshift; Positions=195; Sequence=BAG62525.1; Type=Frameshift;
Positions=195; Sequence=EAW85085.1; Type=Frameshift; Positions=195;
Secondary accessions: B4DV13 D6RGD3 Q05D05 Q6IAI6 Q8IXL5
Alternative splicing: 2 isoforms:  Q9Y3C1-1   Q9Y3C1-2   (Ref.4 (BAG62525) sequence is in conflict in position: 171:C->F)

Explore the universe of human proteins at neXtProt for NOP16: NX_Q9Y3C1

Explore proteomics data for NOP16 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NOP16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001243468.2  NP_001243469.2  NP_001278234.1  NP_001278235.1  NP_001278236.1  NP_001278237.1  NP_057475.2  

    ENSEMBL proteins: 
     ENSP00000421302   ENSP00000373810   ENSP00000426392   ENSP00000423835   ENSP00000427489  

    NOP16 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein for NOP16
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    OriGene MassSpec for NOP16
    OriGene Custom Protein Services for NOP16
    GenScript Custom Purified and Recombinant Proteins Services for NOP16
    Novus Biologicals NOP16 Proteins
    Novus Biologicals NOP16 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for NOP16
    Cloud-Clone Corp. Proteins for NOP16

    NOP16 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for NOP16
    Novus Biologicals NOP16 Antibodies
    Search for Antibodies for NOP16 at Abcam
    Cloud-Clone Corp. Antibodies for NOP16
    Search ThermoFisher Antibodies for NOP16
    LSBio Antibodies in human, mouse, rat for NOP16

    NOP16 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NOP16
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NOP16
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NOP16
    Cloud-Clone Corp. CLIAs for NOP16


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019002 Ribosome_biogenesis_Nop16

    Graphical View of Domain Structure for InterPro Entry Q9Y3C1

    ProtoNet protein and cluster: Q9Y3C1

    1 Blocks protein domain: IPB011986 Extradiol ring-cleavage dioxygenase LigAB

    UniProtKB/Swiss-Prot: NOP16_HUMAN, Q9Y3C1
    Similarity: Belongs to the NOP16 family


    NOP16 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    NOP16 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NOP16:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NOP16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NOP16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOP16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOP16

    miRNA
    Products:
        
    miRTarBase miRNAs that target NOP16:
    hsa-mir-125a-5p (MIRT021296), hsa-mir-10a-5p (MIRT025600)

    Block miRNA regulation of human, mouse, rat NOP16 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NOP16
    SwitchGear 3'UTR luciferase reporter plasmidNOP16 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NOP16
    Predesigned siRNA for gene silencing in human, mouse, rat NOP16

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NOP16

    Clone
    Products:
         
    OriGene clones in human, mouse for NOP16 (see all 7)
    OriGene ORF clones in mouse, rat for NOP16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOP16 (NM_016391)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOP16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOP16

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NOP16
    Browse ESI BIO Cell Lines and PureStem Progenitors for NOP16 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOP16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NOP16_HUMAN, Q9Y3C1: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    NOP16 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NOP16
    Interactions:

        Search GeneGlobe Interaction Network for NOP16

    1 Interacting protein for NOP16 (Q9Y3C13) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKAA1Q131313I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NOP16



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NOP16 gene (7 alternative transcripts): 
    NM_001256539.2  NM_001256540.2  NM_001291305.1  NM_001291306.1  NM_001291307.1  NM_001291308.1  NM_016391.6  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000510123(uc003med.3) ENST00000389158(uc003mee.3 uc011dfl.2)
    ENST00000507413 ENST00000502663 ENST00000503849 ENST00000504821 ENST00000509257
    ENST00000502577 ENST00000510608(uc011dfm.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NOP16 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NOP16
    SwitchGear 3'UTR luciferase reporter plasmidNOP16 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NOP16
    Predesigned siRNA for gene silencing in human, mouse, rat NOP16
    Clone
    Products:
         
    OriGene clones in human, mouse for NOP16 (see all 7)
    OriGene ORF clones in mouse, rat for NOP16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOP16 (NM_016391)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOP16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOP16
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NOP16
    OriGene qSTAR qPCR primer pairs in human, mouse for NOP16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOP16
      QuantiTect SYBR Green Assays in human, mouse, rat NOP16
      QuantiFast Probe-based Assays in human, mouse, rat NOP16

    Selected AceView cDNA sequences (see all 312):

    BM801703 CR611555 BE465915 AL550036 AY561704 AI272806 CB050026 BX281362 
    BM756015 BM738729 BQ220893 AW405978 AI659857 AI560269 BU158790 BE613491 
    BM823951 AI474505 BU956451 BF739847 BM831324 BQ683538 BI861405 BE797119 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NOP16 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e
    SP1:                                            -     -     -           -           -                                       
    SP2:                                            -     -     -           -           -     -                                 
    SP3:                                            -     -     -           -           -     -     -                           
    SP4:                                            -                       -           -     -                                 
    SP5:                                            -     -     -           -           -     -                                 


    ECgene alternative splicing isoforms for NOP16

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NOP16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATCAGAAG
    NOP16 Expression
    About this image

    NOP16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NOP16 Protein Expression
        Custom PCR Arrays for NOP16
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NOP16
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    QuantiTect SYBR Green Assays in human, mouse, rat NOP16
    QuantiFast Probe-based Assays in human, mouse, rat NOP16
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOP16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NOP16 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nop161 , 5 NOP16 nucleolar protein homolog (yeast)5
    NOP16 nucleolar protein1
    88.2(n)1
    91.01(a)1
      13 (28.83 cM)5
    281261  NM_178605.41  NP_848720.11 
     545841855 
    chicken
    (Gallus gallus)
    Aves NOP161 NOP16 nucleolar protein homolog (yeast) 72.85(n)
    74.16(a)
      416228  XM_414551.4  XP_414551.2 
    lizard
    (Anolis carolinensis)
    Reptilia NOP166
    NOP16 nucleolar protein
    52(a)
    1 ↔ 1
    GL343548.1(337502-344448)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nop161 NOP16 nucleolar protein 61.22(n)
    58.49(a)
      100124769  NM_001102748.1  NP_001096218.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nop161 NOP16 nucleolar protein homolog (yeast) 56.83(n)
    51.2(a)
      436807  NM_001002534.1  NP_001002534.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK265.66
    Protein ZK265.6 (ZK265.6) mRNA, complete cds
    20(a)
    1 ↔ 1
    I(8255346-8256315) WBGene00013958


    ENSEMBL Gene Tree for NOP16 (if available)
    TreeFam Gene Tree for NOP16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NOP16 (see all 85)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs68628461,2
    C,F,A--175810529(+) TGGGGG/ACCTCG 3 -- int18Minor allele frequency- A:0.21NA CSA WA EA 368
    rs68625221,2
    C,F,A--175810533(+) GACCTC/TGGATT 3 -- int17Minor allele frequency- T:0.13NA CSA WA 248
    rs1909944921,2
    C--175810607(+) GGCAGA/GCCAGG 3 -- int10--------
    rs772850281,2
    C--175810693(+) GGGGGA/GACTAG 3 -- int10--------
    rs22415781,2
    C,F,H--175810714(+) GCAGGC/ACCCTT 3 -- int115Minor allele frequency- A:0.27EA NA NS WA CSA 2385
    rs68631221,2
    C,F,A,H--175810837(+) GTGAAC/TGTAGC 3 -- int118Minor allele frequency- T:0.12NS EA NA WA 2046
    rs115563821,2
    H--175811025(+) TTTCCG/CTGAAC 5 /T /R mis1 ut31 ese34Minor allele frequency- C:0.00NS EA 406
    rs412752711,2
    F--175811082(+) AGAGCA/GGGGAG 5 P L mis1 ut310--------
    rs2014284851,2
    C--175811094(-) CACACA/GTGCAC 5 H R mis1 ut310--------
    rs1118676621,2
    C--175811121(+) CATGGA/C/GACCTG 8 S C F mis1 ut311CSA 1

    HapMap Linkage Disequilibrium report for NOP16 (175810949 - 175815976 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NOP16: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing NOP16
    DNA2.0 Custom Variant and Variant Library Synthesis for NOP16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612861    OMIM disorders: --

    1 disease for NOP16:    
    About MalaCards
    breast cancer


    NOP16 for disorders           About GeneDecksing


    Export disorders for NOP16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOP16 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with NOP16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    5. The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome. (PubMed id 18373870)1, 9 Butt A.J....Musgrove E.A. (Breast Cancer Res. 2008)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51491 HGNC: 26934 AceView: HSPC111 Ensembl:ENSG00000048162 euGenes: HUgn51491
    ECgene: NOP16 H-InvDB: NOP16

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NOP16 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NOP16 gene:
    Search GeneIP for patents involving NOP16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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