NOP10 Gene
protein-coding GIFtS: 54
GCID: GC15M034633
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|
NOP10 ribonucleoprotein(Previous names: nucleolar protein family A, member 3 (H/ACA small nucleolar...)
(Previous symbol: NOLA3)
| |
Aliases
for NOP10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NOP10 Ribonucleoprotein1 2 | | MGC706511 | | NOLA31 2 3 5 | | NOP10 Ribonucleoprotein Homolog (Yeast)1 | | NOP10P1 2 | | DKCB12 | | Nucleolar Protein Family A, Member 3 (H/ACA Small Nucleolar RNPs)1 2 | | H/ACA Ribonucleoprotein Complex Subunit 32 | | Nucleolar Protein 102 3 | | Homolog Of Yeast Nop10p2 | | Nucleolar Protein Family A Member 32 3 | | NOP10 Ribonucleoprotein Homolog2 | | SnoRNP Protein NOP102 3 | | |
Export aliases for NOP10 gene to outside databasesPrevious GC identifers: GC15M032422 GC15M011497 |
Summaries
for NOP10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NOP10:
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved invarious aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. TheH/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the densefibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNApseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are alsocomponents of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NOP10_HUMAN, Q9NPE3Function: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolarribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerizationof uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required forcorrect processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme
|
Genomic Views
for NOP10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NOP10 gene promoter:
MyoD FOXD1 Lmo2 AP-4 CUTL1 C/EBPalpha GATA-2 PPAR-gamma1 SEF-1 (1) PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for NOP10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOP10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q14-q15 Ensembl cytogenetic band: 15q14 HGNC cytogenetic band: 15q14-q15NOP10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M034633: view genomic region
(about GC identifiers)
Start:
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34,633,917 bp from pter |
End:
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34,635,378 bp from pter |
Size:
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1,462 bases |
Orientation:
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minus strand |
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Proteins
for NOP10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NOP10_HUMAN, Q9NPE3 (See
protein sequence)Recommended Name: H/ACA ribonucleoprotein complex subunit 3 Size: 64 amino acids; 7706 Da
Subunit: Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which contains NHP2/NOLA2,GAR1/NOLA1, NOP10/NOLA3, and DKC1/NOLA4, which is presumed to be the catalytic subunit. The complex contains a stablecore formed by binding of one or two NOP10-DKC1 heterodimers to NHP2; GAR1 subsequently binds to this core via DKC1.The complex binds a box H/ACA small nucleolar RNA (snoRNA), which may target the specific site of modification withinthe RNA substrate. During assembly, the complex contains NAF1 instead of GAR1/NOLA1. The complex also interacts withTERC, which contains a 3'-terminal domain related to the box H/ACA snoRNAs. Specific interactions with snoRNAs or TERCare mediated by GAR1 and NHP2. Associates with NOLC1/NOPP140. H/ACA snoRNPs interact with the SMN complex, consistingof SMN1 or SMN2, GEMIN2/SIP1, DDX20/GEMIN3, and GEMIN4. This is mediated by interaction between GAR1 and SMN1 or SMN2.The SMN complex may be required for correct assembly of the H/ACA snoRNP complex. Component of the telomeraseholoenzyme complex at least composed of TERT, DKC1, WRAP53/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and atelomerase RNA template component (TERC)
Subcellular location: Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies)Explore the universe of human proteins at neXtProt for NOP10: NX_Q9NPE3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPE3
NOP10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_061118.1
ENSEMBL proteins: ENSP00000332198 ENSP00000453475
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NOP10 for ontologies About GeneDecksing
NOP10 Antibody Products:
Assay Products for NOP10: |
Protein
Domains /
Families
for NOP10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NOP10 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NPE3ProtoNet protein and cluster: Q9NPE3 1 Blocks protein family: IPB007264 Nucleolar RNA-binding protein Nop10p
UniProtKB/Swiss-Prot: NOP10_HUMAN, Q9NPE3Similarity: Belongs to the NOP10 family |
Function
for NOP10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NOP10_HUMAN, Q9NPE3Function: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolarribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerizationof uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required forcorrect processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NOP10 (NM_018648) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NOP10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOP10 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
NOP10 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for NOP10:
|
Pathways & Interactions
for NOP10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ribosome biogenesis in eukaryotes | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for NOP10):
NOP10 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NOP10
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/17 Interacting proteins for NOP10 (Q9NPE33 ENSP000003321984) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
NOP10 for ontologies About GeneDecksing
|
Drugs & Compounds
for NOP10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NOP10 for compounds About GeneDecksing
 Browse Tocris compounds for NOP10
2 Novoseek chemical compound relationships for NOP10 gene About this table
Search CenterWatch for drugs/clinical trials and news about NOP10
|
Transcripts
for NOP10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NOP10 gene: NM_018648.3 Unigene Cluster for NOP10: NOP10 ribonucleoprotein Hs.14317 [show with all ESTs]Unigene Representative Sequence: CF5963842 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000328848(uc001zie.1) ENST00000557912
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NOP10 (NM_018648) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NOP10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOP10 |
Additional cDNA sequence: AB043104.1 BC008886.2 BC063023.1 9 DOTS entries: DT.319408 DT.121064740 DT.91759139 DT.95273853 DT.86854773 DT.91759143 DT.92325594 DT.121064739 DT.97867251 24/335 AceView cDNA sequences (see all 335): AA155999 AA934691 BP431793 D80676 AV710400 AA083998 CA453345 AI004418 BM916715 H78183 AI695124 AA157384 H58463 BM826533 BM846103 AA962579 AA035030 AA905911 D80435 AA112121 AA398357 BX119250 BQ438156 AI718796
GeneLoc Exon Structure
|
Expression
for NOP10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NOP10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGGCATCAC
About this image
See NOP10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NOP10
SOURCE GeneReport for Unigene cluster: Hs.14317
SABiosciences Expression via Pathway-Focused PCR Array including NOP10:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NOP10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NOP10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOP10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOP10 |
Orthologs
for NOP10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NOP10 gene from 8/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Nop101 , 5 |
NOP10 ribonucleoprotein homolog (yeast)5
NOP10 ribonucleoprotein1 |
94.27(n)1
100(a)1 |
|
2 (56.99 cM)5
661811 NM_025403.31 NP_079679.11
1122619265 |
lizard
(Anolis carolinensis) |
Reptilia |
NOP106 |
-- |
86(a) |
1 ↔ 1 |
GL343220.1(845221-848247) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.80282 |
Xenopus laevis transcribed sequence with moderate similarity more |
75.97(n) |
|
48024189 |
zebrafish
(Danio rerio) |
Actinopterygii |
nop101 |
NOP10 ribonucleoprotein homolog (yeast) |
71.87(n)
81.25(a) |
|
445391 NM_001003868.2 NP_001003868.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG76371 |
CG7637 |
61.9(n)
66.67(a) |
|
36135 NM_136766.1 NP_610610.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
nola-36 |
Putative H/ACA ribonucleoprotein complex subunit 3... |
59(a) |
1 ↔ 1 |
I(10179032-10179226) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NOP106 |
H/ACA ribonucleoprotein complex subunit 3-like pro... |
58(a) |
1 ↔ 1 |
2(8831716-8832916) |
rice
(Oryza sativa) |
Liliopsida |
-- |
h/ACA ribonucleoprotein complex subunit 3, putativ... |
66(a) |
1 ↔ 1 |
2(24567521-24569475) |
ENSEMBL Gene Tree for NOP10 (if available)
TreeFam Gene Tree for NOP10 (if available) |
Paralogs
for NOP10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NOP10 gene
NOP10 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for NOP10
PGOHUM00000261147 PGOHUM00000244361
|
Genomic Variants
for NOP10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NOP10 (34633917 - 34635378 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for NOP10
4 CNVs: 0783 0187 3957 7058
Human Gene Mutation Database (HGMD): NOP10
Locus Specific Mutation Databases (LSDB): NOP10
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOP10 |
|
Disorders
/ Diseases
for NOP10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NOP10 for disorders About GeneDecksing
OMIM gene information: 606471
OMIM disorders: 224230
UniProtKB/Swiss-Prot: NOP10_HUMAN, Q9NPE3
Defects in NOP10 are a cause of dyskeratosis congenita autosomal recessive type 1 (DKCB1) [MIM:224230]. A raremultisystem disorder caused by defective telomere maintenance. It is characterized by progressive bone marrow failure,and the clinical triad of reticulated skin hyperpigmentation, nail dystrophy, and mucosal leukoplakia. Common butvariable features include premature graying, aplastic anemia, low platelets, osteoporosis, pulmonary fibrosis, andliver fibrosis among others. Early mortality is often associated with bone marrow failure, infections, fatal pulmonarycomplications, or malignancy
8  diseases for NOP10: About MalaCardsdyskeratosis congenita autosomal recessive dyskeratosis congenita dyskeratosis aplastic anemia
leukoplakia anemia osteoporosis malaria
1 disease from the University of Copenhagen DISEASES database for NOP10:Dyskeratosis congenita 1 Novoseek disease relationship for NOP10 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| dyskeratosis congenita |
94.9 |
4 |
18239083 (1), 18989882 (1), 20008900 (1), 18252230 (1) |
Human Genome Epidemiology (HuGE) Navigator: NOP10 (3 documents)
Export disorders for NOP10 gene to outside databases
|
Publications
for NOP10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NOP10 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with NOP10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. (PubMed id 11074001)1, 2, 3, 9 Pogacic V.... Filipowicz W. (2000)
- Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10. (PubMed id 17507419)1, 2, 9 Walne A.J....Dokal I. (2007)
- hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase. (PubMed id 16601202)1, 2 Hoareau-Aveilla C....Henry Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins. (PubMed id 15044956)1, 2 Wang C. and Meier U.T. (2004)
- Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs. (PubMed id 9843512)1, 3 Henras A....Caizergues-Ferrer M. (1998)
- Effects of dyskeratosis congenita mutations in dysker in, NHP2 and NOP10 on assembly of H/ACA pre-RNPs. (PubMed id 20008900)1, 9 Trahan C....Dragon F. (2010)
- Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP. (PubMed id 19095616)1, 9 Trahan C. and Dragon F. (2009)
- Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. (PubMed id 15814878)1, 9 Yamaguchi H.... Young N.S. (2005)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for NOP10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NOP10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NOP10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NOP10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NOP10 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NOP10 gene:
Search GeneIP for patents involving NOP10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NOP10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for NOP10 | | OriGene shRNA RFP for NOP10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NOP10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NOP10 | | | OriGene Protein Over-expression Lysate for NOP10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NOP10 | | OriGene 3'-UTR Clone for NOP10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NOP10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NOP10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOP10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOP10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOP10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOP10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOP10 |
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 | | | NOP10 Proteins, Antibodies, CLIAs, and ELISAs |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOP10 |
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