Aliases for NOMO2 Gene
External Ids for NOMO2 Gene
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for NOMO2 Gene
NOMO2 (NODAL Modulator 2) is a Protein Coding gene. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is NOMO1.
UniProtKB/Swiss-Prot for NOMO2 Gene
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN.