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NOM1 Gene

protein-coding   GIFtS: 53
GCID: GC07P156742

Nucleolar Protein With MIF4G Domain 1

(Previous name: chromosome 7 open reading frame 3)
(Previous symbol: C7orf3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nucleolar Protein With MIF4G Domain 11 2
C7orf31 2 3 5
SGD1 Homolog2 3
Chromosome 7 Open Reading Frame 31
SGD12
Nucleolar MIF4G Domain-Containing Protein 12

External Ids:    HGNC: 132441   Entrez Gene: 644342   Ensembl: ENSG000001469097   OMIM: 6112695   UniProtKB: Q5C9Z43   

Export aliases for NOM1 gene to outside databases

Previous GC identifers: GC00U921619 GC07P156242 GC07P156435 GC07P150475


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NOM1 Gene:
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein
translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA
helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 (PubMed 15715967)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NOM1 Gene:
NOM1 (nucleolar protein with MIF4G domain 1) is a protein-coding gene. Diseases associated with NOM1 include ovarian mucinous adenocarcinoma, and mucinous adenocarcinoma. GO annotations related to this gene include RNA binding.

UniProtKB/Swiss-Prot: NOM1_HUMAN, Q5C9Z4
Function: Plays a role in targeting PPP1CA to the nucleolus

Gene Wiki entry for NOM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NOM1 gene promoter:
         Nkx6-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOM1 promoter sequence
   Search Chromatin IP Primers for NOM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NOM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.3   Ensembl cytogenetic band:  7q36.3   HGNC cytogenetic band: 7q36.3

NOM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOM1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P156742:  view genomic region     (about GC identifiers)

Start:
156,742,417 bp from pter      End:
156,765,876 bp from pter
Size:
23,460 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 155,971,818-155,995,224     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NOM1_HUMAN, Q5C9Z4 (See protein sequence)
Recommended Name: Nucleolar MIF4G domain-containing protein 1  
Size: 860 amino acids; 96257 Da
Subunit: May interact with EIF4A1, EIF4A2 and EIF4A3. Interacts with PPP1CA and PPP1CC
Secondary accessions: Q96I08

Explore the universe of human proteins at neXtProt for NOM1: NX_Q5C9Z4

Explore proteomics data for NOM1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NOM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_612409.1  
    ENSEMBL proteins: 
     ENSP00000275820  

    NOM1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for NOM1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR003891 Initiation_fac_eIF4g_MI
     IPR016024 ARM-type_fold
     IPR003890 MIF4G-like_typ-3
     IPR016021 MIF4-like_typ_1/2/3

    Graphical View of Domain Structure for InterPro Entry Q5C9Z4

    ProtoNet protein and cluster: Q5C9Z4

    2 Blocks protein domains:
    IPB003890 Initiation factor eIF-4 gamma
    IPB003891 Initiation factor eIF-4 gamma


    UniProtKB/Swiss-Prot: NOM1_HUMAN, Q5C9Z4
    Similarity: Belongs to the CWC22 family
    Similarity: Contains 1 MI domain
    Similarity: Contains 1 MIF4G domain


    NOM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NOM1_HUMAN, Q5C9Z4
    Function: Plays a role in targeting PPP1CA to the nucleolus

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0005488binding ----
    GO:0005515protein binding IPI17965019
    GO:0044822poly(A) RNA binding IDA--
         
    NOM1 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for NOM1:
     Decreased Hepatitis C virus re  Decreased cilium length after   Increased gamma-H2AX phosphory  Nuclear pre-40S maturation def 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NOM1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOM1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOM1

    miRNA
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    miRTarBase miRNAs that target NOM1:
    hsa-mir-484 (MIRT041667)

    Block miRNA regulation of human, mouse, rat NOM1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate NOM1:
    hsa-miR-3130-3p hsa-miR-1284
    SwitchGear 3'UTR luciferase reporter plasmidNOM1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NOM1

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    GenScript: all cDNA clones in your preferred vector: NOM1 (NM_138400)
    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOM1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NOM1_HUMAN, Q5C9Z4: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    NOM1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NOM1
    Interactions:

        Search GeneGlobe Interaction Network for NOM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NOM1 (Q5C9Z42, 3 ENSP000002758204) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAP621362, 3MINT-62187 I2D: score=3 
    PNKPQ96T603, ENSP000003235114I2D: score=1 STRING: ENSP00000323511
    CLN3Q132863I2D: score=1 
    EEF1DP296923I2D: score=1 
    TFCP2Q128003I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    NOM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NOM1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NOM1 gene: 
    NM_138400.1  

    Unigene Cluster for NOM1:

    Nucleolar protein with MIF4G domain 1
    Hs.15825  [show with all ESTs]
    Unigene Representative Sequence: AY576779
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000275820(uc003wmy.3) ENST00000460332 ENST00000475176 ENST00000472491
    ENST00000489850 ENST00000469271(uc010lqp.1) ENST00000485661 ENST00000486131

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NOM1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate NOM1:
    hsa-miR-3130-3p hsa-miR-1284
    SwitchGear 3'UTR luciferase reporter plasmidNOM1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NOM1
    Predesigned siRNA for gene silencing in human, mouse, rat NOM1
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    OriGene ORF clones in mouse, rat for NOM1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOM1 (NM_138400)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOM1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NOM1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOM1
      QuantiTect SYBR Green Assays in human, mouse, rat NOM1
      QuantiFast Probe-based Assays in human, mouse, rat NOM1

    Additional mRNA sequence: 

    AF107455.1 AK131362.1 AK308719.1 AY576779.1 BC007902.2 BC011187.1 

    10 DOTS entries:

    DT.208610  DT.102831442  DT.100648068  DT.100740249  DT.121069552  DT.95368107  DT.100717109  DT.91877446 
    DT.92043226  DT.97837194 

    Selected AceView cDNA sequences (see all 80):

    AI636505 BC007902 BU191301 BU189397 AW264413 BQ962613 AK131362 BU540689 
    BX462095 AI419857 BX955715 BM552155 BU167584 BE348368 AF107455 BG437838 
    BG575410 AA558928 BG250895 AI637959 BF306283 CF785984 AL708087 BF038646 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NOM1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b
    SP1:                                                                          -           -                 -                     
    SP2:                                                                          -           -                                       
    SP3:                          -                                                                                                   
    SP4:                          -                                                                                                   
    SP5:                                                                          -                                                   


    ECgene alternative splicing isoforms for NOM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NOM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATTGCTGCC
    NOM1 Expression
    About this image


    NOM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
    NOM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NOM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.15825

    UniProtKB/Swiss-Prot: NOM1_HUMAN, Q5C9Z4
    Tissue specificity: Expressed in heart and skeletal muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NOM1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nom11 , 5 nucleolar protein with MIF4G domain 11, 5 76.14(n)1
    76.52(a)1
      5 (15.00 cM)5
    4338641  NM_001033457.21  NP_001028629.21 
     294346645 
    chicken
    (Gallus gallus)
    Aves NOM11 nucleolar protein with MIF4G domain 1 72.42(n)
    72.55(a)
      420446  XM_418549.4  XP_418549.3 
    lizard
    (Anolis carolinensis)
    Reptilia NOM16
    nucleolar protein with MIF4G domain 1
    57(a)
    1 ↔ 1
    6(6370785-6383908)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ030745.12   -- 79.32(n)    BJ030745.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.60262 Transcribed sequence with weak similarity to protein more 69.05(n)    57062060 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90041 CG9004 49.42(n)
    40.5(a)
      38303  NM_139460.2  NP_647717.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y52B11A.101 CELE_Y52B11A.10 42.1(n)
    31.67(a)
      173006  NM_060460.4  NP_492861.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SGD1(YLR336C)4 Essential nuclear protein, required for biogenesis more   --   12(802396-799697) 851049  NP_013440.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G179301 AT5G17930 47.11(n)
    35.49(a)
      831661  NM_121799.3  NP_197295.2 
    rice
    (Oryza sativa)
    Liliopsida Os.189962 Oryza sativa (japonica cultivar-group) cDNA clone0 more 73.25(n)    AK064493.1 


    ENSEMBL Gene Tree for NOM1 (if available)
    TreeFam Gene Tree for NOM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NOM1 (see all 856)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1165823111,2
    F--156740427(+) GAGAGC/TAGACT 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1924401931,2
    C--156740509(+) GGCAGC/GGAAGG 1 -- us2k10--------
    rs1449648001,2
    C--156740622(+) CACAG-/CACACAC 1 -- us2k10--------
    rs29691191,2
    C,H--156740684(+) AATGAG/TATATT 1 -- us2k112Minor allele frequency- T:0.11NA WA CSA EA 373
    rs1852407811,2
    --156740859(+) TTGAGA/GGAGGA 1 -- us2k10--------
    rs1173222731,2
    C,F--156740930(+) CTTGCC/TGGGTG 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1885548611,2
    --156740947(+) CTCACA/GCCTGT 1 -- us2k10--------
    rs1448932601,2
    --156741013(+) AGGGAA/GACCCT 1 -- us2k10--------
    rs1388311111,2
    --156741197(+) TGACAA/TAAATT 1 -- us2k10--------
    rs744399961,2
    C--156741209(+) AATCAT/CTTTAA 1 -- us2k13Minor allele frequency- C:0.19NA EA 242

    HapMap Linkage Disequilibrium report for NOM1 (156742417 - 156765876 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for NOM1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2735655CNV Deletion23290073
    nsv889568CNV Loss21882294
    nsv889569CNV Loss21882294
    nsv465249CNV Loss19166990
    nsv824415CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing NOM1
    DNA2.0 Custom Variant and Variant Library Synthesis for NOM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611269    OMIM disorders: --

    9 diseases for NOM1:    
    About MalaCards
    ovarian mucinous adenocarcinoma    mucinous adenocarcinoma    polydactyly    brain cancer
    acute myeloid leukemia    myeloid leukemia    adenocarcinoma    leukemia
    malaria


    NOM1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NOM1
    Human Genome Epidemiology (HuGE) Navigator: NOM1 (1 document)

    Export disorders for NOM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOM1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with NOM1)
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    1. A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36. (PubMed id 10329000)1, 2, 3 Heus H.C.... Heutink P. (Genomics 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. NOM1 targets protein phosphatase I to the nucleolus. (PubMed id 17965019)1, 2 Gunawardena S.R.... Conklin K.F. (J. Biol. Chem. 2008)
    4. Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. (PubMed id 15715967)1, 2 Simmons H.M.... Conklin K.F. (Gene 2005)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex. (PubMed id 21576267)1 Alexandrov A....Steitz J.A. (amp 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64434 HGNC: 13244 AceView: C7orf3 Ensembl:ENSG00000146909 euGenes: HUgn64434
    ECgene: NOM1 H-InvDB: NOM1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NOM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NOM1 gene:
    Search GeneIP for patents involving NOM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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