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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NOL9 Gene

protein-coding   GIFtS: 45
GCID: GC01M006581

Nucleolar Protein 9

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleolar Protein 91 2 3
Polynucleotide 5'-Kinase1 2
Grc32
NET62
Polynucleotide 5'-Hydroxyl-Kinase NOL92
EC 2.7.1.-3

External Ids:    HGNC: 262651   Entrez Gene: 797072   Ensembl: ENSG000001624087   UniProtKB: Q5SY163   

Export aliases for NOL9 gene to outside databases

Previous GC identifers: GC01M006520 GC01M005729


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NOL9 Gene: 
NOL9 (nucleolar protein 9) is a protein-coding gene. Diseases associated with NOL9 include choroiditis. GO annotations related to this gene include RNA binding and polynucleotide 5'-hydroxyl-kinase activity.

UniProtKB/Swiss-Prot: NOL9_HUMAN, Q5SY16
Function: Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing
of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In
vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA

Gene Wiki entry for NOL9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_021937.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NOL9 gene promoter:
         MyoD   FOXO3   FOXO3b   AREB6   POU2F1   POU2F1a   FOXO3a   PPAR-gamma2   Hlf   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOL9 promoter sequence
   Search SABiosciences Chromatin IP Primers for NOL9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOL9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.31   Ensembl cytogenetic band:  1p36.31   HGNC cytogenetic band: 1p36.31

NOL9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOL9 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M006581:  view genomic region     (about GC identifiers)

Start:
6,581,407 bp from pter      End:
6,614,658 bp from pter
Size:
33,252 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NOL9_HUMAN, Q5SY16 (See protein sequence)
Recommended Name: Polynucleotide 5'-hydroxyl-kinase NOL9  
Size: 702 amino acids; 79323 Da
Subunit: Interacts with PELP1, WDR18 and SENP3 (By similarity)
Subcellular location: Nucleus (By similarity). Nucleus, nucleolus. Note=Colocalizes with pre-60S rRNP particles
Sequence caution: Sequence=BAB15611.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q2NL84 Q4VBY3 Q6P472 Q7L4D6 Q96EE0 Q9H5L4

Explore the universe of human proteins at neXtProt for NOL9: NX_Q5SY16

Explore proteomics data for NOL9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5SY16

  • NOL9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NOL9 Protein Expression
    REFSEQ proteins: NP_078930.3  
    ENSEMBL proteins: 
     ENSP00000366934  

    Human Recombinant Protein Products for NOL9: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NOL9 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus TAS--

    NOL9 for ontologies           About GeneDecksing



    NOL9 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR010655 Pre-mRNA_cleavage_cplxII_Clp1

    Graphical View of Domain Structure for InterPro Entry Q5SY16

    ProtoNet protein and cluster: Q5SY16

    UniProtKB/Swiss-Prot: NOL9_HUMAN, Q5SY16
    Similarity: Belongs to the Clp1 family. NOL9/GRC3 subfamily


    NOL9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NOL9_HUMAN, Q5SY16
    Function: Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing
    of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In
    vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA

         Enzyme Number (IUBMB): EC 2.7.1.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0005524ATP binding TAS--
    GO:0051731polynucleotide 5'-hydroxyl-kinase activity IDA--
         
    NOL9 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for NOL9:
     Decreased nuclei size in G2M  Decreased viability of wild-ty  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NOL9 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOL9
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NOL9:
    hsa-miR-642a hsa-miR-4267 hsa-miR-3667-3p
    SwitchGear 3'UTR luciferase reporter plasmidNOL9 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NOL9

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for NOL9 (Q5SY163 ENSP000003669344) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    SUMO2P619563, ENSP000004059654I2D: score=1 STRING: ENSP00000405965
    UBCENSP000003448184STRING: ENSP00000344818
    SIRT7ENSP000003294664STRING: ENSP00000329466
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000460maturation of 5.8S rRNA IMP--

    NOL9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NOL9

    Search CenterWatch for drugs/clinical trials and news about NOL9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NOL9 gene: 
    NM_024654.4  

    Unigene Cluster for NOL9:

    Nucleolar protein 9
    Hs.59425  [show with all ESTs]
    Unigene Representative Sequence: NM_024654
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377705(uc001ans.3 uc010nzs.2) ENST00000464383 ENST00000462798
    ENST00000460777 ENST00000464665
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOL9
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NOL9:
    hsa-miR-642a hsa-miR-4267 hsa-miR-3667-3p
    SwitchGear 3'UTR luciferase reporter plasmidNOL9 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NOL9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOL9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOL9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOL9

    Additional mRNA sequence: 

    AK026976.1 AK091284.1 AK289653.1 BC009257.2 BC012439.1 BC063639.1 BC073860.1 BC094836.1 
    BC105095.1 BC110849.1 BC112278.1 BC143646.1 

    10 DOTS entries:

    DT.445929  DT.97842025  DT.91940181  DT.100761804  DT.91875388  DT.100725257  DT.91954283  DT.95110332 
    DT.95258026  DT.439414 

    24/93 AceView cDNA sequences (see all 93):

    BM852027 AI253686 T70351 AA504370 BC063639 BX282410 AI075717 NM_024654 
    AK091284 CB109356 CA435061 CA430349 BE898310 AX746895 BF223494 AA504112 
    CD632184 BE396475 BC073860 AW769708 AA243422 BI869420 AA343037 BM856367 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NOL9    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                          -           -     -                                                         
    SP2:                                                                                                      
    SP3:                                                        -                                             
    SP4:                                                                                                      


    ECgene alternative splicing isoforms for NOL9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NOL9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NOL9 Expression
    About this image


    See NOL9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NOL9

    SOURCE GeneReport for Unigene cluster: Hs.59425
        SABiosciences Custom PCR Arrays for NOL9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NOL9 gene from 9/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nol91 , 5 nucleolar protein 91, 5 71.17(n)1
    62.12(a)1
      4 (82.84 cM)5
    740351  NM_001159599.11  NP_001153071.11 
     1520393215 
    chicken
    (Gallus gallus)
    Aves LOC7701911 polynucleotide 5'-hydroxyl-kinase NOL9-like 61.39(n)
    61.74(a)
      770191  XM_001233521.2  XP_001233522.2 
    lizard
    (Anolis carolinensis)
    Reptilia NOL96
    nucleolar protein 9
    49(a)
    1 ↔ 1
    GL343320.1(1343097-1362156)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.63092 Transcribed sequence with weak similarity to protein more 78.63(n)    AL862852.2 
    zebrafish
    (Danio rerio)
    Actinopterygii nol91 nucleolar protein 9 51.62(n)
    43.66(a)
      567715  XM_691014.2  XP_696106.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84141 CG8414 40.41(n)
    25.85(a)
      36774  NM_137240.3  NP_611084.2 
    worm
    (Caenorhabditis elegans)
    Secernentea nol-96
    Polynucleotide 5'-hydroxyl-kinase nol-9
    21(a)
    1 ↔ 1
    IV(13422498-13429374)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G110101 Pre-mRNA cleavage complex II protein family 47.74(n)
    37.74(a)
      830968  NM_180474.1  NP_850805.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g01840001 hypothetical protein 46.73(n)
    37.03(a)
      4325340  NM_001048765.1  NP_001042230.1 


    ENSEMBL Gene Tree for NOL9 (if available)
    TreeFam Gene Tree for NOL9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NOL9 gene

    NOL9 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NOL9
    PGOHUM00000241094


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/813 SNPs in NOL9 are shown (see all 813)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0547794
    ----see VAR_0547792 S A mis40--------
    VAR_0547774
    ----see VAR_0547772 R W mis40--------
    VAR_0547784
    ----see VAR_0547782 W R mis40--------
    rs1830373611,2
    --6582144(+) CTCACA/GCCTGT 1 -- ut310--------
    rs1868117001,2
    --6582213(+) AGCCTA/GGCCAA 1 -- ut310--------
    rs1912711211,2
    --6582246(+) TAAAAA/GTACAA 1 -- ut310--------
    rs1161247421,2
    C,F--6582269(+) AGTGTA/GGTGGC 1 -- ut311Minor allele frequency- G:0.04WA 118
    rs1493699921,2
    --6582274(+) AGTGGC/TGGGCG 1 -- ut310--------
    rs1437192531,2
    C--6582614(+) AGAAAA/CAAACA 1 -- ut310--------
    rs1842462831,2
    --6582658(+) GAATAC/GCTTCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NOL9 (6581407 - 6614658 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NOL9:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831536CNV Loss17160897
    nsv831647CNV Loss17160897
    nsv7880CNV Gain+Loss18304495

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NOL9
    DNA2.0 Custom Variant and Variant Library Synthesis for NOL9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for NOL9:    About MalaCards
    choroiditis    


    NOL9 for disorders           About GeneDecksing


    Export disorders for NOL9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NOL9 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with NOL9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nol9 is a novel polynucleotide 5'-kinase involved in ribosomal RNA processing. (PubMed id 21063389)1, 2, 3 Heindl K. and Martinez J. (2010)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    8. LAS1L interacts with the mammalian Rix1 complex to reg ulate ribosome biogenesis. (PubMed id 22190735)1 Castle C.D....Denicourt C. (2012)
    9. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    10. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79707 HGNC: 26265 AceView: FLJ23323 Ensembl:ENSG00000162408 euGenes: HUgn79707
    ECgene: NOL9 H-InvDB: NOL9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NOL9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NOL9 gene:
    Search GeneIP for patents involving NOL9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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