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Aliases for NOL7 Gene

Aliases for NOL7 Gene

  • Nucleolar Protein 7, 27kDa 2 3
  • Polyglutamine Binding Protein 3 2 3
  • Nucleolar Protein Of 27 KDa 3 4
  • C6orf90 3 4
  • Chromosome 6 Open Reading Frame 90 2
  • Retinoic Acid Repressible Protein 3
  • Nucleolar Protein 7 3
  • DJ223E5.2 3
  • RARG-1 3
  • PQBP3 3
  • NOP27 4

External Ids for NOL7 Gene

Previous Symbols for NOL7 Gene

  • C6orf90
  • PQBP3

Summaries for NOL7 Gene

GeneCards Summary for NOL7 Gene

NOL7 (Nucleolar Protein 7, 27kDa) is a Protein Coding gene.

Gene Wiki entry for NOL7 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOL7 Gene

Genomics for NOL7 Gene

Genomic Location for NOL7 Gene

Start:
13,615,327 bp from pter
End:
13,632,857 bp from pter
Size:
17,531 bases
Orientation:
Plus strand

Genomic View for NOL7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NOL7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NOL7 Gene

Regulatory Elements for NOL7 Gene

Proteins for NOL7 Gene

  • Protein details for NOL7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UMY1-NOL7_HUMAN
    Recommended name:
    Nucleolar protein 7
    Protein Accession:
    Q9UMY1
    Secondary Accessions:
    • Q5T297
    • Q9Y3U7

    Protein attributes for NOL7 Gene

    Size:
    257 amino acids
    Molecular mass:
    29426 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB43398.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=CAI19840.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for NOL7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NOL7 Gene

Proteomics data for NOL7 Gene at MOPED

Post-translational modifications for NOL7 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys170 and Lys210

Other Protein References for NOL7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NOL7 Gene

Domains for NOL7 Gene

Protein Domains for NOL7 Gene

InterPro:
Blocks:
ProtoNet:
genes like me logo Genes that share domains with NOL7: view

No data available for Gene Families and UniProtKB/Swiss-Prot for NOL7 Gene

Function for NOL7 Gene

Gene Ontology (GO) - Molecular Function for NOL7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with NOL7: view

miRNA for NOL7 Gene

miRTarBase miRNAs that target NOL7

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for NOL7 Gene

Localization for NOL7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NOL7 Gene

Nucleus, nucleolus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NOL7 Gene COMPARTMENTS Subcellular localization image for NOL7 gene
Compartment Confidence
nucleus 5
mitochondrion 4
cytosol 2

Gene Ontology (GO) - Cellular Components for NOL7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with NOL7: view

Pathways for NOL7 Gene

SuperPathways for NOL7 Gene

No Data Available

Interacting Proteins for NOL7 Gene

Gene Ontology (GO) - Biological Process for NOL7 Gene

None

No data available for Pathways by source for NOL7 Gene

Transcripts for NOL7 Gene

mRNA/cDNA for NOL7 Gene

Unigene Clusters for NOL7 Gene

Nucleolar protein 7, 27kDa:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NOL7 Gene

No ASD Table

Relevant External Links for NOL7 Gene

GeneLoc Exon Structure for
NOL7
ECgene alternative splicing isoforms for
NOL7

Expression for NOL7 Gene

mRNA expression in normal human tissues for NOL7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for NOL7 Gene

SOURCE GeneReport for Unigene cluster for NOL7 Gene Hs.306242

mRNA Expression by UniProt/SwissProt for NOL7 Gene

Q9UMY1-NOL7_HUMAN
Tissue specificity: Expressed in numerous tissues. Particularly prevalent in the adrenal gland, thyroid gland, heart and skeletal muscle.
genes like me logo Genes that share expressions with NOL7: view

Orthologs for NOL7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NOL7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NOL7 36
  • 99.61 (n)
  • 100 (a)
NOL7 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NOL7 36
  • 87.89 (n)
  • 88.28 (a)
NOL7 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NOL7 36
  • 87.19 (n)
  • 85.49 (a)
NOL7 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nol7 36
  • 83 (n)
  • 77.69 (a)
Nol7 16
Nol7 37
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NOL7 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NOL7 37
  • 43 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nol7 36
  • 82.8 (n)
  • 80.24 (a)
chicken
(Gallus gallus)
Aves NOL7 36
  • 57.42 (n)
  • 47.12 (a)
NOL7 37
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NOL7 37
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100489073 36
  • 56.24 (n)
  • 45.25 (a)
zebrafish
(Danio rerio)
Actinopterygii nol7 36
  • 53.14 (n)
  • 43.53 (a)
nol7 37
  • 38 (a)
OneToOne
Species with no ortholog for NOL7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NOL7 Gene

ENSEMBL:
Gene Tree for NOL7 (if available)
TreeFam:
Gene Tree for NOL7 (if available)

Paralogs for NOL7 Gene

No data available for Paralogs for NOL7 Gene

Variants for NOL7 Gene

Sequence variations from dbSNP and Humsavar for NOL7 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs3757260 -- 13,620,645(-) TATAC(A/T)TTAGA intron-variant
rs3757262 -- 13,616,480(-) GTGTC(A/T)GGAAG reference, synonymous-codon
rs3800503 -- 13,619,397(+) CATTC(A/G)TTTGA intron-variant
rs3823453 -- 13,619,192(+) GAAAG(C/G)TTGTT intron-variant
rs6937316 -- 13,617,750(+) CAGTG(A/G)TTTTG intron-variant

Relevant External Links for NOL7 Gene

HapMap Linkage Disequilibrium report
NOL7

No data available for Structural Variations from Database of Genomic Variants (DGV) for NOL7 Gene

Disorders for NOL7 Gene

(1) University of Copenhagen DISEASES for NOL7 Gene

Relevant External Links for NOL7

Human Genome Epidemiology (HuGE) Navigator
NOL7
genes like me logo Genes that share disorders with NOL7: view

No data available for UniProtKB/Swiss-Prot for NOL7 Gene

Publications for NOL7 Gene

  1. NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. (PMID: 16205646) Hasina R. … Lingen M.W. (Oncogene 2006) 2 3 4
  2. Directed proteomic analysis of the human nucleolus. (PMID: 11790298) Andersen J.S. … Lamond A.I. (Curr. Biol. 2002) 3 4
  3. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for NOL7 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate NOL7
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for NOL7
    • Block miRNA regulation of NOL7 using miScript Target Protectors

    Sources for NOL7 Gene

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