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NOL6 Gene

protein-coding   GIFtS: 54
GCID: GC09M033451

Nucleolar Protein 6 (RNA-Associated)

(Previous name: nucleolar protein family 6 (RNA-associated))
  Search for NOL6
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nucleolar Protein 6 (RNA-Associated)1 2     UTP222
Nucleolar Protein Family 6 (RNA-Associated)1 2     bA311H10.12
Nucleolar RNA-Associated Protein2 3     Nucleolar Protein 62
NRAP2 5     Nrap3

External Ids:    HGNC: 199101   Entrez Gene: 650832   Ensembl: ENSG000001652717   OMIM: 6115325   UniProtKB: Q9H6R43   

Export aliases for NOL6 gene to outside databases

Previous GC identifer: GC09M033630


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NOL6 Gene:
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and
functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved
between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA
dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction
with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants
encoding distinct isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for NOL6 Gene:
NOL6 (nucleolar protein 6 (RNA-associated)) is a protein-coding gene. GO annotations related to this gene include RNA binding.

Gene Wiki entry for NOL6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the NOL6 gene promoter:
         RFX1   USF1   AML1a   Bach2   Lmo2   MZF-1   FAC1   USF-1   SEF-1 (1)   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOL6 promoter sequence
   Search Chromatin IP Primers for NOL6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NOL6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.3   Ensembl cytogenetic band:  9p13.3   HGNC cytogenetic band: 9p12

NOL6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOL6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M033451:  view genomic region     (about GC identifiers)

Start:
33,461,351 bp from pter      End:
33,473,941 bp from pter
Size:
12,591 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NOL6_HUMAN, Q9H6R4 (See protein sequence)
Recommended Name: Nucleolar protein 6  
Size: 1146 amino acids; 127593 Da
Subunit: Probably associated with rRNA
Sequence caution: Sequence=AAH08298.1; Type=Erroneous initiation; Sequence=BAB15189.1; Type=Erroneous initiation;
Sequence=BAB15389.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=CAI13312.1; Type=Erroneous
gene model prediction; Sequence=CAI13313.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5T5M3 Q5T5M4 Q7L4G6 Q8N6I0 Q8TEY9 Q8TEZ0 Q8TEZ1 Q9H675
Alternative splicing: 4 isoforms:  Q9H6R4-1   Q9H6R4-2   Q9H6R4-3   Q9H6R4-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NOL6: NX_Q9H6R4

Explore proteomics data for NOL6 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys271
  • Modification sites at PhosphoSitePlus

  • See NOL6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_075068.2  NP_631981.2  

    ENSEMBL proteins: 
     ENSP00000313978   ENSP00000368783   ENSP00000297990   ENSP00000368784   ENSP00000395915  

    NOL6 Human Recombinant Protein Products:

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    Novus Biologicals NOL6 Protein
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    Cloud-Clone Corp. Proteins for NOL6

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005554 Nrap

    Graphical View of Domain Structure for InterPro Entry Q9H6R4

    ProtoNet protein and cluster: Q9H6R4

    UniProtKB/Swiss-Prot: NOL6_HUMAN, Q9H6R4
    Similarity: Belongs to the NRAP family


    Find genes that share domains with NOL6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ISS11895476
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with NOL6           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for NOL6:
     Increased circadian period len  Nucleolar pre-40S maturation d  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NOL6
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOL6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOL6

    miRNA
    Products:
        
    miRTarBase miRNAs that target NOL6:
    hsa-mir-18a-3p (MIRT040840), hsa-mir-193b-3p (MIRT041565), hsa-let-7b-5p (MIRT032331)

    Block miRNA regulation of human, mouse, rat NOL6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NOL6 (see all 16):
    hsa-miR-3173-3p hsa-miR-4303 hsa-miR-875-3p hsa-miR-627 hsa-miR-485-3p hsa-miR-551b* hsa-miR-3921 hsa-miR-3160-3p
    SwitchGear 3'UTR luciferase reporter plasmidNOL6 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NOL6
    Predesigned siRNA for gene silencing in human, mouse, rat NOL6

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOL6

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    Browse ESI BIO Cell Lines and PureStem Progenitors for NOL6 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NOL6_HUMAN, Q9H6R4: Nucleus, nucleolus. Chromosome (By similarity). Note=Localizes to condensed chromosomes in
    mitosis (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion3
    cytosol2
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000794condensed nuclear chromosome ISS11895476
    GO:0005634nucleus IDA--
    GO:0005730nucleolus ISS--
    GO:0005739mitochondrion IDA--

    Find genes that share ontologies with NOL6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NOL6 About    
    See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes


    Find genes that share SuperPaths with NOL6           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for NOL6):
        Ribosome biogenesis in eukaryotes

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NOL6
    Interactions:

        Search GeneGlobe Interaction Network for NOL6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NOL6 (Q9H6R43 ENSP000002979904) via UniProtKB, MINT, STRING, and/or I2D (see all 342)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing ISS--

    Find genes that share ontologies with NOL6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NOL6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NOL6 gene (3 alternative transcripts): 
    NM_022917.4  NM_139235.3  NM_130793.3  

    Unigene Cluster for NOL6:

    Nucleolar protein 6 (RNA-associated)
    Hs.493709  [show with all ESTs]
    Unigene Representative Sequence: NM_022917
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000353159(uc003zta.3) ENST00000379470(uc003zsy.3) ENST00000297990(uc003zsz.3 uc010mjv.3 uc011lob.2)
    ENST00000379471(uc003ztb.1) ENST00000464829 ENST00000496319 ENST00000455041

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NOL6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NOL6 (see all 16):
    hsa-miR-3173-3p hsa-miR-4303 hsa-miR-875-3p hsa-miR-627 hsa-miR-485-3p hsa-miR-551b* hsa-miR-3921 hsa-miR-3160-3p
    SwitchGear 3'UTR luciferase reporter plasmidNOL6 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NOL6
    Predesigned siRNA for gene silencing in human, mouse, rat NOL6
    Clone
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    OriGene ORF clones in mouse, rat for NOL6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): NOL6 (NM_022917)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOL6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOL6
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NOL6
    OriGene qSTAR qPCR primer pairs in human, mouse for NOL6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOL6
      QuantiTect SYBR Green Assays in human, mouse, rat NOL6
      QuantiFast Probe-based Assays in human, mouse, rat NOL6

    Additional mRNA sequence: 

    AF361079.1 AF361080.1 AF361081.1 AK025612.1 AK026193.1 AK056559.1 AK293969.1 BC008298.1 
    BC008852.2 BC020450.1 BC030139.2 

    13 DOTS entries:

    DT.445221  DT.121155218  DT.210534  DT.99939872  DT.121155194  DT.101982208  DT.121155206  DT.100796244 
    DT.100796245  DT.101964699  DT.121155200  DT.75103549  DT.97781578 

    Selected AceView cDNA sequences (see all 290):

    BU502706 AW452501 BQ437239 BC030139 BU542459 AA312507 AW264086 BE867337 
    BQ218257 AI992085 AI401522 BQ066617 BM909561 AW007026 AA031603 BU543453 
    NM_022917 AW071892 AK025612 AW613992 BQ878563 BE257106 AA913182 AW298288 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NOL6 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a ·
    SP1:                                                                                      -                                                                 -   
    SP2:                                                                                      -                                                                 -   
    SP3:                                                              -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21b ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25 ^ 26a · 26b · 26c
    SP1:        -                                                   
    SP2:        -                                                   
    SP3:  -     -     -     -     -     -     -     -               
    SP4:        -                                                   
    SP5:                                                            


    ECgene alternative splicing isoforms for NOL6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NOL6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NOL6 Expression
    About this image

    NOL6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NOL6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.493709
        Custom PCR Arrays for NOL6
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat NOL6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NOL6 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nol61 , 5 nucleolar protein family 6 (RNA-associated)1, 5 85.28(n)1
    85.63(a)1
      4 (20.98 cM)5
    2300821  NM_139236.31  NP_631982.21 
     411144275 
    chicken
    (Gallus gallus)
    Aves NOL61 nucleolar protein 6 (RNA-associated) 63.62(n)
    62.25(a)
      100858366  XM_004937086.1  XP_004937143.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    61(a)
    59(a)
    many → 1
    many → 1
    GL343372.1(643933-722001)
    AAWZ02039032(481-9487)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.38102 Xenopus laevis transcribed sequence with weak similarity more 71.83(n)    48016069 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi43b022 Transcribed sequence with weak similarity to protein more 71.3(n)    57092637 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mat89Ba1 Maternal transcript 89Ba 45.78(n)
    36.67(a)
      41973  NM_142273.4  NP_650530.2 
    worm
    (Caenorhabditis elegans)
    Secernentea nol-66
    Protein NOL-6 (nol-6) mRNA, complete cds
    25(a)
    1 ↔ 1
    II(1425732-1437499) WBGene00021789
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP22(YGR090W)4
    UTP221
    Possible U3 snoRNP protein involved in maturation of more4
    UTP221
    40.55(n)1
    30.35(a)1
      7(662358-666071)4
    8529821, 4  NP_011604.31  NP_011604.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G638101 AT1G63810 43.69(n)
    33.83(a)
      842684  NM_105056.3  NP_176566.3 


    ENSEMBL Gene Tree for NOL6 (if available)
    TreeFam Gene Tree for NOL6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NOL6 (see all 549)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1864574921,2
    --33460970(+) GAGGAC/TGGAGC 2 -- ds50010--------
    rs799146671,2
    F--33461080(+) CGGCTC/TGTTAT 2 -- ds50011Minor allele frequency- T:0.01WA 118
    rs1924831081,2
    --33461118(+) GATACA/GGATAC 2 -- ds50010--------
    rs1145131511,2
    F--33461213(+) CACCCA/CCTTCT 2 -- ds50011Minor allele frequency- C:0.01WA 118
    rs126834381,2
    C,F,H--33461299(+) TGCTGG/AATGGC 2 -- ds500127Minor allele frequency- A:0.11NA EA NS WA CSA 2627
    rs1116590441,2
    C,F--33461374(+) CTTGCC/TCTCAA 2 -- ut311Minor allele frequency- T:0.50CSA 2
    rs1470013031,2
    C--33461428(+) GCAGAC/TAGGCC 2 -- ut310--------
    rs1159086801,2
    C,F--33461442(+) AATACG/AGGGGA 2 -- ut311Minor allele frequency- A:0.03WA 118
    rs1173326951,2
    C,F--33461560(+) GATTAC/TAAGCA 2 -- ut311Minor allele frequency- T:0.02EA 120
    rs6788591,2
    C,F,A,H--33461567(-) TGGCTC/TATGCT 2 -- ut31 ese314Minor allele frequency- T:0.40MN NA WA CSA EA 564

    HapMap Linkage Disequilibrium report for NOL6 (33461351 - 33473941 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NOL6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv527128CNV Loss19592680
    nsv516500CNV Loss19592680
    nsv518168CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NOL6
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611532    OMIM disorders: --


    Find genes that share disorders with NOL6           About GenesLikeMe

    Genetic Association Database (GAD): NOL6

    Export disorders for NOL6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOL6 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with NOL6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. (PubMed id 11895476)1, 2, 3, 9 Utama B.... Mattick J.S. (Genes Cells 2002)
    2. The small-subunit processome is a ribosome assembly intermediate. (PubMed id 15590835)1, 3 Bernstein K.A....Baserga S.J. (Eukaryotic Cell 2004)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    7. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    8. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 65083 HGNC: 19910 AceView: NOL6 Ensembl:ENSG00000165271 euGenes: HUgn65083
    ECgene: NOL6 Kegg: 65083 H-InvDB: NOL6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NOL6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NOL6 gene:
    Search GeneIP for patents involving NOL6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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