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Aliases for NOL4L Gene

Aliases for NOL4L Gene

  • Nucleolar Protein 4-Like 2 3
  • C20orf112 3 4
  • C20orf113 3 4
  • Chromosome 20 Open Reading Frame 113 2
  • Chromosome 20 Open Reading Frame 112 2
  • Hypothetical Protein LOC140688 2
  • DJ1184F4.2 3
  • DJ1184F4.4 3

External Ids for NOL4L Gene

Previous HGNC Symbols for NOL4L Gene

  • C20orf113
  • C20orf112

Summaries for NOL4L Gene

GeneCards Summary for NOL4L Gene

NOL4L (Nucleolar Protein 4-Like) is a Protein Coding gene. An important paralog of this gene is NOL4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOL4L Gene

Genomics for NOL4L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NOL4L Gene

Start:
32,443,059 bp from pter
End:
32,585,074 bp from pter
Size:
142,016 bases
Orientation:
Minus strand

Genomic View for NOL4L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NOL4L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NOL4L Gene

No data available for Regulatory Elements for NOL4L Gene

Proteins for NOL4L Gene

  • Protein details for NOL4L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MY1-NOL4L_HUMAN
    Recommended name:
    Nucleolar protein 4-like
    Protein Accession:
    Q96MY1
    Secondary Accessions:
    • Q5JYB7
    • Q6P0Y4
    • Q9BR34
    • Q9NQF6

    Protein attributes for NOL4L Gene

    Size:
    436 amino acids
    Molecular mass:
    47215 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NOL4L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NOL4L Gene

Proteomics data for NOL4L Gene at MOPED

Post-translational modifications for NOL4L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NOL4L Gene

Domains for NOL4L Gene

Protein Domains for NOL4L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NOL4L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NOL4L Gene

Function for NOL4L Gene

Gene Ontology (GO) - Molecular Function for NOL4L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NOL4L: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NOL4L Gene

Localization for NOL4L Gene

Gene Ontology (GO) - Cellular Components for NOL4L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with NOL4L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for NOL4L Gene

Pathways for NOL4L Gene

SuperPathways for NOL4L Gene

No Data Available

Interacting Proteins for NOL4L Gene

Gene Ontology (GO) - Biological Process for NOL4L Gene

None

No data available for Pathways by source for NOL4L Gene

Transcripts for NOL4L Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NOL4L

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NOL4L Gene

No ASD Table

Relevant External Links for NOL4L Gene

GeneLoc Exon Structure for
NOL4L
ECgene alternative splicing isoforms for
NOL4L

Expression for NOL4L Gene

mRNA expression in normal human tissues for NOL4L Gene

Protein differential expression in normal tissues for NOL4L Gene

This gene is overexpressed in Fetal Brain (40.8), Retina (21.1), and Testis (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for NOL4L Gene

genes like me logo Genes that share expressions with NOL4L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NOL4L Gene

Orthologs for NOL4L Gene

This gene was present in the common ancestor of animals.

Orthologs for NOL4L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C13H20orf112 35
  • 92.22 (n)
  • 96.69 (a)
C20orf112 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 8430427H17Rik 35
  • 91.02 (n)
  • 96.17 (a)
8430427H17Rik 16
8430427H17Rik 36
  • 61 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf112 35
  • 99.33 (n)
  • 99.27 (a)
C20orf112 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20orf112 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C20orf112 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 23 (a)
ManyToMany
chicken
(Gallus gallus)
Aves C20H20ORF112 35
  • 85.14 (n)
  • 91.04 (a)
C20orf112 36
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C20orf112 36
  • 13 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c20orf112 35
  • 69.97 (n)
  • 71.29 (a)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-80n10.2 35
  • 65.74 (n)
  • 65.18 (a)
wufa08e04 35
C23H20orf112 (1 of 2) 36
  • 62 (a)
OneToMany
C8H20orf112 (2 of 2) 36
  • 39 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG16879 36
  • 8 (a)
OneToOne
Species with no ortholog for NOL4L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NOL4L Gene

ENSEMBL:
Gene Tree for NOL4L (if available)
TreeFam:
Gene Tree for NOL4L (if available)

Paralogs for NOL4L Gene

Paralogs for NOL4L Gene

genes like me logo Genes that share paralogs with NOL4L: view

Variants for NOL4L Gene

Sequence variations from dbSNP and Humsavar for NOL4L Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs11725 -- 32,444,199(+) GGTAG(A/T)TACAG utr-variant-3-prime
rs176814 -- 32,498,767(+) TCAAT(A/T)AAAAA intron-variant
rs293533 -- 32,476,731(+) cccct(C/T)gatcc intron-variant, upstream-variant-2KB
rs293534 -- 32,477,687(+) AGCCC(A/G)GGATG intron-variant
rs293535 -- 32,478,378(+) ATAAC(C/T)AAGGC intron-variant

Relevant External Links for NOL4L Gene

HapMap Linkage Disequilibrium report
NOL4L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NOL4L Gene

Disorders for NOL4L Gene

No disorders were found for NOL4L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NOL4L Gene

Publications for NOL4L Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Large-scale characterization of HeLa cell nuclear phosphoproteins. (PMID: 15302935) Beausoleil S.A. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2004) 2 3
  4. CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia. (PMID: 20520637) Guastadisegni M.C. … Storlazzi C.T. (Leukemia 2010) 2 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for NOL4L Gene

Sources for NOL4L Gene

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