NOL4 Gene

Aliases
for NOL4 gene

Previous GC identifers: GC18M031251 GC18M029684 GC18M029686 GC18M028290

Summaries
for NOL4 gene

Genomic Views
for NOL4 gene

RefSeq DNA sequence:

NC_000018.9  NC_018929.1  NT_010966.14  

SwitchGear Promoter luciferase reporter plasmid: NOL4 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOL4

NOL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M031465:  view genomic region     (about GC identifiers)

Proteins
for NOL4 gene

Explore the universe of human proteins at neXtProt for NOL4: NX_O94818

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: NOL4 OriGene Protein Over-expression Lysate (see all 3): NOL4 OriGene Custom Protein Services for NOL4
	GenScript Custom Purified and Recombinant Proteins Services for NOL4
	Novus Biologicals NOL4 Proteins Novus Biologicals NOL4 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NOL4

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for NOL4
	GenScript Custom Superior Antibodies Services for NOL4
	Novus Biologicals NOL4 Antibodies
	Search for Antibodies for NOL4 at Abcam
	Uscn Antibodies for NOL4
	Search ThermoFisher Antibodies for NOL4

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for NOL4
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NOL4

Protein Domains /
Families
for NOL4 gene

ProtoNet protein and cluster: O94818

Function
for NOL4 gene

miRNA Products:		OriGene 3'-UTR Clone: NOL4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOL4
		8/81 QIAGEN miScript miRNA Assays for microRNAs that regulate NOL4 (see all 81):
		hsa-miR-411* hsa-miR-323-3p hsa-miR-548j hsa-miR-106a hsa-miR-128 hsa-miR-219-5p hsa-miR-519a hsa-miR-10b*
		SwitchGear 3'UTR luciferase reporter plasmid: NOL4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NOL4 (see all 7) OriGene shRNA RFP: NOL4 OriGene siRNA: NOL4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOL4

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for NOL4

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NOL4 (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NOL4 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 5): NOL4 (NM_001198547)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOL4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOL4

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NOL4
		Search LifeMap BioReagents cell lines for NOL4

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL4

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

Pathways & Interactions
for NOL4 gene

Drugs & Compounds
for NOL4 gene

Transcripts
for NOL4 gene

Expression
for NOL4 gene

NOL4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAATTTAT

3 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Neural TubeNeural TubeSpinal Neural Tube Cells			Neural Ectoderm
	EyeRetina			Eye
	Spinal CordPresumptive Spinal Cord			Spinal Cord
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NOL4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NOL4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOL4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOL4

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL4

Orthologs
for NOL4 gene

Paralogs
for NOL4 gene

Paralogs for NOL4 gene

C20orf112²  

2 SIMAP similar genes for NOL4 using alignment to 7 protein entries:     NOL4_HUMAN (see all proteins):

C20orf112    LOC284804

NOL4 for paralogs           About GeneDecksing

Genomic Variants
for NOL4 gene

10/5352 NCBI SNPs in NOL4 are shown (see all 5352)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs617438571,2		--	28663769(+)	CAGACT/CAAATC	1	--	nc-transcript-variant		2		NS NA	194
rs28527451,2	H	--	31430695(+)	AAGGCA/CAAGTA	6	--	int1		4		NS EA	394
rs752718111,2		--	31430714(+)	GCACTT/CAAAAC	6	--	int1		1		NA	120
rs1814406031,2		--	31430772(+)	AACAGA/GTTACT	6	--	int1		0	--	--	--	--
rs1858770011,2		--	31430928(+)	CTTAGA/GATATT	6	--	int1		0	--	--	--	--
rs1147404491,2	F,	--	31430972(+)	CTAAAC/TGTAGG	6	--	int1		1		WA	118
rs1912593741,2		--	31431371(+)	TTACTC/TGGTCA	6	--	ut31 nc-transcript-variant		0	--	--	--	--
rs1814293941,2		--	31431402(+)	AAAACC/TATATG	6	--	ut31 nc-transcript-variant		0	--	--	--	--
rs1860657901,2		--	31431466(+)	AATGAC/TATAAA	6	--	nc-transcript-variantut31		0	--	--	--	--
rs1908831981,2		--	31431472(+)	ATAAAC/TTTTAC	6	--	ut31 nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for NOL4 (31431064 - 31681064 bp, first 250kb of NOL4)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for NOL4
     1 CNV: 88781
     5 Indels: 45641 11941 26028 42989 11940

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOL4

DNA2.0 Custom Variant and Variant Library Synthesis for NOL4

Disorders / Diseases
for NOL4 gene

Publications
for NOL4 gene

PubMed articles for NOL4 gene, integrated from 9 sources (see all 17): (articles sorted by number of sources associating them with NOL4)

Utopia: connect your pdf to the dynamic world of online information

1. NOLP: identification of a novel human nucleolar protein and determination of sequence requirements for its nucleolar localization. (PubMed id 9813152)^{1, 2, 3} Ueki N....Muramatsu M.-A. (1998)
2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
4. Selection system for genes encoding nuclear-targeted proteins. (PubMed id 9853615)^{1, 2} Ueki N.... Muramatsu M.-A. (1998)
5. Genetic variants associated with breast size also infl uence breast cancer risk. (PubMed id 22747683)¹ Eriksson N....Tung J.Y. (2012)
6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
7. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)¹ Emanuele M.J....Elledge S.J. (2011)
8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
9. A genomewide association study of citalopram response in major depressive disorder. (PubMed id 19846067)¹ Garriock H.A....Hamilton S.P. (2010)
10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)

External Searches for NOL4 gene

Genome Databases showing NOL4 gene

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Products
for NOL4 gene