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NOL10 Gene

protein-coding   GIFtS: 48
GCID: GC02M010662

Nucleolar Protein 10

(Previous name: polyglutamine binding protein 5)
(Previous symbol: PQBP5)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nucleolar Protein 101 2
PQBP51 2
Polyglutamine Binding Protein 51 2
H_NH0074G24.12

External Ids:    HGNC: 258621   Entrez Gene: 799542   Ensembl: ENSG000001157617   UniProtKB: Q9BSC43   

Export aliases for NOL10 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NOL10 Gene:
NOL10 (nucleolar protein 10) is a protein-coding gene. Diseases associated with NOL10 include multiple myeloma, and myeloma.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005334.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the NOL10 gene promoter:
         Bach2   p300   YY1   Evi-1   E47   CREB   POU2F1   POU2F1a   deltaCREB   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOL10 promoter sequence
   Search Chromatin IP Primers for NOL10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NOL10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25.1   Ensembl cytogenetic band:  2p25.1   HGNC cytogenetic band: 2p25.1

NOL10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOL10 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M010662:  view genomic region     (about GC identifiers)

Start:
10,710,892 bp from pter      End:
10,830,112 bp from pter
Size:
119,221 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NOL10_HUMAN, Q9BSC4 (See protein sequence)
Recommended Name: Nucleolar protein 10  
Size: 688 amino acids; 80302 Da
Secondary accessions: A8K3R5 B4DLV0 Q53RC9 Q96TA5 Q9H7Y7 Q9H855
Alternative splicing: 4 isoforms:  Q9BSC4-1   Q9BSC4-2   Q9BSC4-3   Q9BSC4-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NOL10: NX_Q9BSC4

Explore proteomics data for NOL10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys74
  • Modification sites at PhosphoSitePlus

  • See NOL10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001248321.1  NP_001248323.1  NP_079170.2  

    ENSEMBL proteins: 
     ENSP00000263837   ENSP00000371101   ENSP00000403170   ENSP00000439663   ENSP00000437625  

    NOL10 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for NOL10
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    Novus Biologicals NOL10 Protein
    Novus Biologicals NOL10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for NOL10

    NOL10 Antibody Products:

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    Novus Biologicals NOL10 Antibodies
    Abcam antibodies for NOL10
    Cloud-Clone Corp. Antibodies for NOL10
    Search ThermoFisher Antibodies for NOL10
    LSBio Antibodies in human, mouse, rat for NOL10

    NOL10 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for NOL10
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NOL10
    Cloud-Clone Corp. CLIAs for NOL10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR012580 NUC153
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom
     IPR001680 WD40_repeat

    Graphical View of Domain Structure for InterPro Entry Q9BSC4

    ProtoNet protein and cluster: Q9BSC4

    1 Blocks protein domain: IPB012580 NUC153

    UniProtKB/Swiss-Prot: NOL10_HUMAN, Q9BSC4
    Similarity: Belongs to the WD repeat NOL10/ENP2 family
    Similarity: Contains 5 WD repeats


    NOL10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    NOL10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NOL10:
     Nuclear pre-40S maturation def  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NOL10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NOL10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOL10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOL10

    miRNA
    Products:
        
    miRTarBase miRNAs that target NOL10:
    hsa-mir-124-3p (MIRT022386), hsa-mir-148b-3p (MIRT019297), hsa-mir-935 (MIRT036650)

    Block miRNA regulation of human, mouse, rat NOL10 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate NOL10:
    hsa-miR-16-2* hsa-miR-195* hsa-miR-3175 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidNOL10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NOL10
    Predesigned siRNA for gene silencing in human, mouse, rat NOL10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NOL10

    Clone
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    OriGene clones in human, mouse for NOL10 (see all 10)
    OriGene ORF clones in mouse, rat for NOL10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOL10 (NM_024894)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOL10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOL10

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NOL10
    Browse ESI BIO Cell Lines and PureStem Progenitors for NOL10 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NOL10_HUMAN, Q9BSC4: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus IEA--

    NOL10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NOL10
    Interactions:

        Search GeneGlobe Interaction Network for NOL10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NOL10 (Q9BSC42, 3 ENSP000003711014) via UniProtKB, MINT, STRING, and/or I2D (see all 171)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NOL10



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NOL10 gene (3 alternative transcripts): 
    NM_001261392.1  NM_001261394.1  NM_024894.3  

    Unigene Cluster for NOL10:

    Nucleolar protein 10
    Hs.222494  [show with all ESTs]
    Unigene Representative Sequence: NM_024894
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000345985(uc002raq.2 uc010yje.1 uc010yjf.1 uc002rap.2)
    ENST00000381685(uc002rar.2) ENST00000431319 ENST00000473087 ENST00000538384
    ENST00000542668
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NOL10 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate NOL10:
    hsa-miR-16-2* hsa-miR-195* hsa-miR-3175 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidNOL10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NOL10
    Predesigned siRNA for gene silencing in human, mouse, rat NOL10
    Clone
    Products:
         
    OriGene clones in human, mouse for NOL10 (see all 10)
    OriGene ORF clones in mouse, rat for NOL10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOL10 (NM_024894)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOL10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOL10
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NOL10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NOL10
      QuantiTect SYBR Green Assays in human, mouse, rat NOL10
      QuantiFast Probe-based Assays in human, mouse, rat NOL10

    Additional mRNA sequence: 

    AK024000.1 AK024137.1 AK290680.1 AK297169.1 AK299617.1 BC005125.2 BC037841.1 NR_048552.1 

    12 DOTS entries:

    DT.97813752  DT.92441458  DT.91822604  DT.95114058  DT.455034  DT.92441454  DT.100784258  DT.100736820 
    DT.120941254  DT.120941258  DT.40307494  DT.92023437 

    Selected AceView cDNA sequences (see all 194):

    BX952911 BI870772 AU142750 BQ653250 BQ919963 BX380050 BM450563 BU189248 
    AA320880 CK904285 BQ015358 BM701450 AK024000 CR612766 BQ672892 AU121018 
    CB129943 CR614196 BU189850 AA314293 BC005125 CB119807 AU280228 BU839517 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NOL10    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b
    SP1:        -                             -                                                     -                                                         
    SP2:        -                             -                                   -                 -                                                         
    SP3:        -                             -     -                                                                                                         
    SP4:                                                                                                                                                      
    SP5:        -     -                                                                                                                                       


    ECgene alternative splicing isoforms for NOL10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NOL10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NOL10 Expression
    About this image

    NOL10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NOL10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.222494
        Custom PCR Arrays for NOL10
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOL10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NOL10 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nol101 , 5 nucleolar protein 101, 5 88.5(n)1
    95.05(a)1
      12 (8.07 cM)5
    2174311  NM_001008421.11  NP_001008421.11 
     173484935 
    chicken
    (Gallus gallus)
    Aves NOL101 nucleolar protein 10 78.83(n)
    84.88(a)
      421938  XM_419950.4  XP_419950.1 
    lizard
    (Anolis carolinensis)
    Reptilia NOL106
    nucleolar protein 10
    82(a)
    1 ↔ 1
    1(147400870-147462074)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC690942 hypothetical protein MGC69094 76.19(n)    BC056086.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556262 hypothetical protein MGC55626 73.02(n)   393206  BC047174.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)34Fd1 lethal (2) 34Fd 54.17(n)
    52.82(a)
      34839  NM_135867.3  NP_609711.1 
    worm
    (Caenorhabditis elegans)
    Secernentea nol-101 nol-10 51.87(n)
    45.73(a)
      177538  NM_068832.4  NP_501233.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ENP21 ENP2 54.68(n)
    49.01(a)
      853048   NP_011661.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons EDA71 EDA7 53.9(n)
    44.64(a)
      824866  NM_115558.5  NP_191258.2 
    rice
    (Oryza sativa)
    Liliopsida Os06g01284001 Os06g0128400 52.83(n)
    44.23(a)
      4339985  NM_001063207.1  NP_001056672.1 


    ENSEMBL Gene Tree for NOL10 (if available)
    TreeFam Gene Tree for NOL10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NOL10 (see all 2890)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs346229871,2
    C--10567013(+) TGTGC-/AAAGTTT 4 -- int11Minor allele frequency- AA:0.00NA 2
    rs1133425761,2
    C--10704542(+) TTTTTT/-CTTTT 4 -- int11Minor allele frequency- -:0.50CSA 2
    rs1857477471,2
    C--10710448(+) GAGAGA/GGAGAG 4 -- int10--------
    rs1155307151,2
    C,F--10710454(+) GAGAGA/TAAGAG 4 -- int11Minor allele frequency- T:0.03WA 118
    rs1441320181,2
    --10710567(+) TTAATC/GCATTC 4 -- int10--------
    rs21602571,2
    C,F,H--10710594(+) CTATTC/TGAAAT 4 -- int125Minor allele frequency- T:0.32EA NA NS WA CSA 2534
    rs1901161861,2
    --10710689(+) TCACAC/TCAAAG 4 -- int10--------
    rs1175744111,2
    C,F--10710708(+) ACTAAG/TGAAAC 4 -- int11Minor allele frequency- T:0.01EA 120
    rs92877191,2
    C,F,H--10710730(+) CTCTTT/CTTTCT 4 -- int111Minor allele frequency- C:0.36NA WA CSA EA 373
    rs561387101,2
    C,F--10710747(+) GAGACG/ACAGGT 4 -- int17Minor allele frequency- A:0.37NA WA CSA EA 366

    HapMap Linkage Disequilibrium report for NOL10 (10710892 - 10830112 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NOL10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv828341CNV Loss20364138
    nsv833381CNV Loss17160897
    nsv828352CNV Gain20364138
    nsv833370CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NOL10
    DNA2.0 Custom Variant and Variant Library Synthesis for NOL10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for NOL10:    
    About MalaCards
    multiple myeloma    myeloma    malaria


    NOL10 for disorders           About GeneDecksing


    Export disorders for NOL10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOL10 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with NOL10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    7. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    8. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PubMed id 22751105)1 Chu L....Tomasson M.H. (J. Clin. Invest. 2012)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79954 HGNC: 25862 AceView: FLJ14075 Ensembl:ENSG00000115761 euGenes: HUgn79954
    ECgene: NOL10 H-InvDB: NOL10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NOL10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NOL10 gene:
    Search GeneIP for patents involving NOL10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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