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Aliases for NOL10 Gene

Aliases for NOL10 Gene

  • Nucleolar Protein 10 2 3
  • Polyglutamine Binding Protein 5 2 3
  • H_NH0074G24.1 3
  • PQBP5 3

External Ids for NOL10 Gene

Previous HGNC Symbols for NOL10 Gene

  • PQBP5

Summaries for NOL10 Gene

GeneCards Summary for NOL10 Gene

NOL10 (Nucleolar Protein 10) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOL10 Gene

Genomics for NOL10 Gene

Regulatory Elements for NOL10 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NOL10 Gene

Start:
10,570,766 bp from pter
End:
10,689,987 bp from pter
Size:
119,222 bases
Orientation:
Minus strand

Genomic View for NOL10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NOL10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NOL10 Gene

Proteins for NOL10 Gene

  • Protein details for NOL10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BSC4-NOL10_HUMAN
    Recommended name:
    Nucleolar protein 10
    Protein Accession:
    Q9BSC4
    Secondary Accessions:
    • A8K3R5
    • B4DLV0
    • Q53RC9
    • Q96TA5
    • Q9H7Y7
    • Q9H855

    Protein attributes for NOL10 Gene

    Size:
    688 amino acids
    Molecular mass:
    80302 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NOL10 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NOL10 Gene

Proteomics data for NOL10 Gene at MOPED

Post-translational modifications for NOL10 Gene

  • Ubiquitination at Lys74
  • Modification sites at PhosphoSitePlus

Other Protein References for NOL10 Gene

No data available for DME Specific Peptides for NOL10 Gene

Domains for NOL10 Gene

Protein Domains for NOL10 Gene

Suggested Antigen Peptide Sequences for NOL10 Gene

Graphical View of Domain Structure for InterPro Entry

Q9BSC4

UniProtKB/Swiss-Prot:

NOL10_HUMAN :
  • Q9BSC4
Family:
  • Belongs to the WD repeat NOL10/ENP2 family.
Similarity:
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with NOL10: view

No data available for Gene Families for NOL10 Gene

Function for NOL10 Gene

Gene Ontology (GO) - Molecular Function for NOL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with NOL10: view

Phenotypes for NOL10 Gene

GenomeRNAi human phenotypes for NOL10:
genes like me logo Genes that share phenotypes with NOL10: view

Animal Model Products

CRISPR Products

miRNA for NOL10 Gene

miRTarBase miRNAs that target NOL10

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for NOL10 Gene

Localization for NOL10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NOL10 Gene

Nucleus, nucleolus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NOL10 Gene COMPARTMENTS Subcellular localization image for NOL10 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for NOL10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with NOL10: view

Pathways for NOL10 Gene

SuperPathways for NOL10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NOL10 Gene

None

No data available for Pathways by source for NOL10 Gene

Transcripts for NOL10 Gene

Unigene Clusters for NOL10 Gene

Nucleolar protein 10:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NOL10

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for NOL10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NOL10 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b
SP1: - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: - -

Relevant External Links for NOL10 Gene

GeneLoc Exon Structure for
NOL10
ECgene alternative splicing isoforms for
NOL10

Expression for NOL10 Gene

mRNA expression in normal human tissues for NOL10 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NOL10 Gene

SOURCE GeneReport for Unigene cluster for NOL10 Gene Hs.222494

genes like me logo Genes that share expressions with NOL10: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NOL10 Gene

Orthologs for NOL10 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NOL10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NOL10 35
  • 99.81 (n)
  • 100 (a)
NOL10 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NOL10 35
  • 90.12 (n)
  • 96.51 (a)
NOL10 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NOL10 35
  • 92.34 (n)
  • 97.38 (a)
NOL10 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nol10 35
  • 88.5 (n)
  • 95.05 (a)
Nol10 16
Nol10 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NOL10 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NOL10 36
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nol10 35
  • 88.91 (n)
  • 95.49 (a)
chicken
(Gallus gallus)
Aves NOL10 35
  • 78.83 (n)
  • 84.88 (a)
NOL10 36
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NOL10 36
  • 82 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC69094 35
tropical clawed frog
(Silurana tropicalis)
Amphibia nol10 35
  • 73.62 (n)
  • 80.61 (a)
Str.1457 35
zebrafish
(Danio rerio)
Actinopterygii nol10 35
  • 66.18 (n)
  • 73.9 (a)
nol10 36
  • 69 (a)
OneToOne
zgc55626 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008159 35
  • 24.42 (n)
  • 4.73 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(2)34Fd 35
  • 54.17 (n)
  • 52.82 (a)
l(2)34Fd 36
  • 43 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea nol-10 35
  • 51.87 (n)
  • 45.73 (a)
nol-10 36
  • 39 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR468W 35
  • 48.25 (n)
  • 41.55 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ENP2 35
  • 54.68 (n)
  • 49.01 (a)
ENP2 36
  • 39 (a)
OneToOne
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0A04653g 35
  • 51.34 (n)
  • 43.31 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons EDA7 35
  • 53.9 (n)
  • 44.64 (a)
rice
(Oryza sativa)
Liliopsida Os06g0128400 35
  • 52.83 (n)
  • 44.23 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU03961 35
  • 49.31 (n)
  • 44.86 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC330.09 35
  • 57.27 (n)
  • 52.6 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8724 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 53 (a)
OneToOne
Species with no ortholog for NOL10:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NOL10 Gene

ENSEMBL:
Gene Tree for NOL10 (if available)
TreeFam:
Gene Tree for NOL10 (if available)

Paralogs for NOL10 Gene

No data available for Paralogs for NOL10 Gene

Variants for NOL10 Gene

Sequence variations from dbSNP and Humsavar for NOL10 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1309 -- 10,603,420(-) GAGGG(C/T)ATAAG intron-variant
rs715246 -- 10,596,229(+) GTTTC(A/G)GAAGA intron-variant
rs715247 -- 10,596,165(+) TCCTA(A/G)CCACA intron-variant
rs728134 -- 10,605,061(-) CAACC(C/T)ATAGG intron-variant
rs728135 -- 10,605,006(+) AATAA(A/C)AGGGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NOL10 Gene

Variant ID Type Subtype PubMed ID
nsv833370 CNV Gain 17160897
nsv828341 CNV Loss 20364138
nsv833381 CNV Loss 17160897
nsv828352 CNV Gain 20364138

Relevant External Links for NOL10 Gene

HapMap Linkage Disequilibrium report
NOL10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NOL10 Gene

Disorders for NOL10 Gene

No disorders were found for NOL10 Gene.

No data available for UniProtKB/Swiss-Prot for NOL10 Gene

Publications for NOL10 Gene

  1. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4

Products for NOL10 Gene

Sources for NOL10 Gene

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