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Aliases for NOC3L Gene

Aliases for NOC3L Gene

  • Nucleolar Complex Associated 3 Homolog (S. Cerevisiae) 2 3
  • FAD24 3 4 6
  • Nucleolar Complex-Associated Protein 3-Like Protein 3 4
  • Factor For Adipocyte Differentiation 24 3 4
  • NOC3 Protein Homolog 3 4
  • C10orf117 3 4
  • AD24 3 4
  • Chromosome 10 Open Reading Frame 117 2
  • Nucleolar Complex Protein 3 Homolog 3
  • NOC3-Like Protein 4

External Ids for NOC3L Gene

Previous Symbols for NOC3L Gene

  • C10orf117

Summaries for NOC3L Gene

GeneCards Summary for NOC3L Gene

NOC3L (Nucleolar Complex Associated 3 Homolog (S. Cerevisiae)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for NOC3L Gene

  • May be required for adipogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NOC3L Gene

Genomics for NOC3L Gene

Genomic Location for NOC3L Gene

Start:
94,333,226 bp from pter
End:
94,362,959 bp from pter
Size:
29,734 bases
Orientation:
Minus strand

Genomic View for NOC3L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NOC3L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NOC3L Gene

Regulatory Elements for NOC3L Gene

Proteins for NOC3L Gene

  • Protein details for NOC3L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WTT2-NOC3L_HUMAN
    Recommended name:
    Nucleolar complex protein 3 homolog
    Protein Accession:
    Q8WTT2
    Secondary Accessions:
    • Q9H5M6
    • Q9H9D8

    Protein attributes for NOC3L Gene

    Size:
    800 amino acids
    Molecular mass:
    92548 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14291.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB15599.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for NOC3L Gene

Proteomics data for NOC3L Gene at MOPED

Post-translational modifications for NOC3L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NOC3L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NOC3L Gene

Domains for NOC3L Gene

Protein Domains for NOC3L Gene

UniProtKB/Swiss-Prot:

NOC3L_HUMAN
Family:
  • Belongs to the CBF/MAK21 family.:
    • Q8WTT2
genes like me logo Genes that share domains with NOC3L: view

No data available for Gene Families for NOC3L Gene

Function for NOC3L Gene

Molecular function for NOC3L Gene

UniProtKB/Swiss-Prot Function: May be required for adipogenesis.

Gene Ontology (GO) - Molecular Function for NOC3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003682 chromatin binding IBA --
GO:0005488 binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with NOC3L: view

miRNA for NOC3L Gene

miRTarBase miRNAs that target NOC3L

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for NOC3L Gene

Localization for NOC3L Gene

Subcellular locations from UniProtKB/Swiss-Prot for NOC3L Gene

Nucleus, nucleolus. Nucleus speckle.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NOC3L Gene COMPARTMENTS Subcellular localization image for NOC3L gene
Compartment Confidence
nucleus 5
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for NOC3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0005730 nucleolus IEA --
GO:0016607 nuclear speck IEA --
genes like me logo Genes that share ontologies with NOC3L: view

Pathways for NOC3L Gene

SuperPathways for NOC3L Gene

No Data Available

Gene Ontology (GO) - Biological Process for NOC3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045444 fat cell differentiation IEA --
genes like me logo Genes that share ontologies with NOC3L: view

No data available for Pathways by source for NOC3L Gene

Transcripts for NOC3L Gene

Unigene Clusters for NOC3L Gene

Nucleolar complex associated 3 homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NOC3L Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^
SP1:
SP2: - -
SP3: -
SP4:

ExUns: 23
SP1:
SP2:
SP3:
SP4:

Relevant External Links for NOC3L Gene

GeneLoc Exon Structure for
NOC3L
ECgene alternative splicing isoforms for
NOC3L

Expression for NOC3L Gene

mRNA expression in normal human tissues for NOC3L Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NOC3L Gene

SOURCE GeneReport for Unigene cluster for NOC3L Gene Hs.74899

mRNA Expression by UniProt/SwissProt for NOC3L Gene

Q8WTT2-NOC3L_HUMAN
Tissue specificity: Expressed in colon, heart, kidney, liver, lung, placenta, skeletal muscle, small intestine, spleen and thymus.
genes like me logo Genes that share expressions with NOC3L: view

Orthologs for NOC3L Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NOC3L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NOC3L 36
  • 99.79 (n)
  • 99.62 (a)
NOC3L 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NOC3L 36
  • 90.14 (n)
  • 93.36 (a)
NOC3L 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NOC3L 36
  • 91.23 (n)
  • 93.61 (a)
NOC3L 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Noc3l 36
  • 85.36 (n)
  • 89.84 (a)
Noc3l 16
Noc3l 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NOC3L 37
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 80 (a)
OneToMany
-- 37
  • 78 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Noc3l 36
  • 85.95 (n)
  • 90.84 (a)
chicken
(Gallus gallus)
Aves NOC3L 36
  • 75.1 (n)
  • 77.82 (a)
NOC3L 37
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NOC3L 37
  • 77 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16127 36
tropical clawed frog
(Silurana tropicalis)
Amphibia noc3l 36
  • 68.99 (n)
  • 69.37 (a)
Str.1945 36
zebrafish
(Danio rerio)
Actinopterygii noc3l 36
  • 65.23 (n)
  • 67.85 (a)
noc3l 37
  • 67 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010308 36
  • 48.19 (n)
  • 37.98 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1234 36
  • 48.5 (n)
  • 39.51 (a)
CG1234 37
  • 31 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C37H5.5 36
  • 47.08 (n)
  • 35.57 (a)
C37H5.5 37
  • 30 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ACR032C 36
  • 44.37 (n)
  • 33.97 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NOC3 36
  • 46.68 (n)
  • 34.8 (a)
NOC3 37
  • 29 (a)
OneToOne
NOC3 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D09735g 36
  • 46.15 (n)
  • 32.97 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G79150 36
  • 45.33 (n)
  • 33.46 (a)
rice
(Oryza sativa)
Liliopsida Os06g0498500 36
  • 46.57 (n)
  • 32.35 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00337 36
  • 44.49 (n)
  • 34.74 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes noc3 36
  • 46.21 (n)
  • 32.48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2414 37
  • 39 (a)
OneToOne
Species with no ortholog for NOC3L:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NOC3L Gene

ENSEMBL:
Gene Tree for NOC3L (if available)
TreeFam:
Gene Tree for NOC3L (if available)

Paralogs for NOC3L Gene

No data available for Paralogs for NOC3L Gene

Variants for NOC3L Gene

Sequence variations from dbSNP and Humsavar for NOC3L Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1678 -- 94,333,875(+) AAGAT(C/G)CAGTC utr-variant-3-prime
rs816278 -- 94,357,803(+) CCGTA(A/G)GAACT intron-variant
rs1093316 -- 94,349,017(+) TTTTT(C/T)ATTTT intron-variant
rs3052365 -- 94,348,941(-) ATATA(-/GGGTTA)TCCCA intron-variant
rs3052367 -- 94,342,554(-) TGTGT(-/GTGT)ATCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NOC3L Gene

Variant ID Type Subtype PubMed ID
nsv831946 CNV Loss 17160897
esv272131 CNV Insertion 20981092
esv2480129 CNV Deletion 19546169

Relevant External Links for NOC3L Gene

HapMap Linkage Disequilibrium report
NOC3L

Disorders for NOC3L Gene

Relevant External Links for NOC3L

Genetic Association Database (GAD)
NOC3L
Human Genome Epidemiology (HuGE) Navigator
NOC3L
genes like me logo Genes that share disorders with NOC3L: view

No data available for UniProtKB/Swiss-Prot for NOC3L Gene

Publications for NOC3L Gene

  1. Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation. (PMID: 15564382) Tominaga K. … Imagawa M. (J. Cell Sci. 2004) 2 3 4
  2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 49
  3. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4

Products for NOC3L Gene

Sources for NOC3L Gene

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