Aliases for NOBOX Gene
External Ids for NOBOX Gene
Previous GeneCards Identifiers for NOBOX Gene
This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure type 5.[provided by RefSeq, May 2011]
GeneCards Summary for NOBOX Gene
NOBOX (NOBOX Oogenesis Homeobox) is a Protein Coding gene. Diseases associated with NOBOX include premature ovarian failure 5 and premature ovarian failure 9. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding.
UniProtKB/Swiss-Prot for NOBOX Gene
Transcription factor which may play a role in oogenesis. Binds preferentially to the DNA sequences 5-TAATTG-3, 5-TAGTTG-3 and 5-TAATTA-3 (By similarity).