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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NOBOX Gene

protein-coding GIFtS: 46
GCID: GC07M144094

NOBOX oogenesis homeobox

Explore 5 diseases affiliated with
NOBOX via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
NOBOX Oogenesis Homeobox¹ ²		OG2X²
OG2¹ ²		TCAG_12042²
POF5² ⁵		Homeobox Protein NOBOX²
Og2x¹		Newborn Ovary Homeobox-Encoding²
OG-2²

External Ids:	HGNC: 22448¹	Entrez Gene: 135935²	Ensembl: ENSG00000106410⁷	OMIM: 610934⁵	UniProtKB: O60393³

Export aliases for NOBOX gene to outside databases

Previous GC identifers: GC07M143533 GC07M143726 GC07M138173

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NOBOX:

This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential

for folliculogenesis and regulation of oocyte-specific genes. Defects in this gene result in premature ovarian failure

type 5.(provided by RefSeq, May 2011)

UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393

Function: Transcription factor which may play a role in oogenesis. Binds preferentially to the DNA sequences

5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3' (By similarity)

Gene Wiki entry for NOBOX

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NOBOX gene promoter:
C/EBPbeta FOXF2 GATA-3 HNF-1A AREB6 POU2F1 POU2F1a HNF-1 Pax-4a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for NOBOX

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOBOX

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q35 Ensembl cytogenetic band: 7q35 HGNC cytogenetic band: 7q35

NOBOX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOBOX gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M144094: view genomic region (about GC identifiers)

Start:	144,094,333 bp from pter	End:	144,107,320 bp from pter
Size:	12,988 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 143,432,585-143,439,039

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393 (See protein sequence)

Recommended Name: Homeobox protein NOBOX

Size: 691 amino acids; 73906 Da

Subcellular location: Nucleus (By similarity)

Sequence caution: Sequence=AAC12957.1; Type=Erroneous gene model prediction;

Secondary accessions: A6NCD3 A8MZN5

Alternative splicing: 2 isoforms: O60393-1 O60393-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NOBOX: NX_O60393

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O60393

NOBOX Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001073882.3

ENSEMBL proteins:

ENSP00000419565 ENSP00000419457 ENSP00000450769 ENSP00000223140

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	Uscn Proteins for NOBOX

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

NOBOX for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NOBOX for domains About GeneDecksing

2 InterPro domains/families:

IPR001356 Homeodomain

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry O60393

ProtoNet protein and cluster: O60393

UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393

Similarity: Contains 1 homeobox DNA-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393

Function: Transcription factor which may play a role in oogenesis. Binds preferentially to the DNA sequences

5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3' (By similarity)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOBOX
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOBOX

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000976	transcription regulatory region sequence-specific DNA binding	--	--
GO:0003677	DNA binding	--	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

NOBOX for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for NOBOX:

Decreased Wnt reporter activit

Animal Models:
Mouse knock-out Nobox^tm1Rajk for NOBOX
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Nobox):

endocrine/exocrine gland

reproductive system

NOBOX for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NOBOX

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001541	ovarian follicle development	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0030154	cell differentiation	IEA	--
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0048477	oogenesis	IEA	--

NOBOX for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NOBOX
Search CenterWatch for drugs/clinical trials and news about NOBOX

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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About This Section

REFSEQ mRNAs for NOBOX gene:

NM_001080413.3

Unigene Cluster for NOBOX:

NOBOX oogenesis homeobox

Hs.558628 [show with all ESTs]

Unigene Representative Sequence: NM_001080413

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000483238 ENST00000467773(uc022aoj.1) ENST00000555556 ENST00000223140

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOBOX
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOBOX
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOBOX

2 DOTS entries:

DT.121116056 DT.121116057

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NOBOX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGCTGACTT

About this image

NOBOX expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Primordial Follicle

Primary Oocyte

Selective marker (cell-identifying gene)

Female Gametocytes, Germ Cells

Ovary

Primary Follicle

Primary Oocyte

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 6 LifeMap Cells

Name

Category

Ovarian tissue-dissociated cells (Primary Cell)

Reproductive System

Ovarian tissue-dissociated cells (human) (Primary Cell)

Ovary, Reproductive System

Human oogonial stem cells (Oocyte formation by ...)

Oocytes (Oocyte formation by ...)

Human oogonial stem cells (Oocyte formation by ...)

See NOBOX Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NOBOX

SOURCE GeneReport for Unigene cluster: Hs.558628

UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393

Tissue specificity: Expressed in ovaries, testes and pancreas. Expressed within all stages of the adult female

germline, from primordial follicles through to MII oocytes

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOBOX

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for NOBOX gene from 5/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nobox^{1 , 5}	NOBOX oogenesis homeobox^{1, 5}	70.27(n)¹ 57.37(a)¹		6 (21.17 cM)⁵ 18291¹ NM_130869.3¹ NP_570939.1¹ 43303674⁵
chicken (Gallus gallus)	Aves	F1NPY3_CHICK⁶	Uncharacterized protein	44(a)	1 ↔ 1	1(76775432-76779851)
lizard (Anolis carolinensis)	Reptilia	NOBOX⁶	--	34(a)	1 ↔ 1	5(82096934-82107253)
African clawed frog (Xenopus laevis)	Amphibia	hbox10-A²	homeobox-containing protein	77.15(n)		L36805.1
zebrafish (Danio rerio)	Actinopterygii	wu:fi69e09⁶	wu:fi69e09	22(a)	1 ↔ 1	19(44793343-44805126)

ENSEMBL Gene Tree for NOBOX (if available)
TreeFam Gene Tree for NOBOX (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs113617436^1,2		--	143432363(+)	`GCCACC/GTGCTT`	1	--	ds500¹		2		CSA WA	120
rs1208215^1,2	C,	--	143432382(+)	`ACCCCC/TACACA`	1	--	ds500¹		5		MN NA WA	426
rs112889438^1,2		--	143432410(+)	`AAGCGC/TCAGCC`	1	--	ds500¹		2		CSA WA	120
rs111712809^1,2		--	143432479(+)	`CCCCTC/TAGTCT`	1	--	ds500¹		1		CSA	2
rs57306880^1,2	C,F,	--	143432508(+)	`CCCAAA/CCCCCC`	1	--	ds500¹		3		WA	122
rs75574842^1,2	C,F,	--	143432970(+)	`CCCCCC/TGTGCC`	1	--	int¹		1		NA	120
rs201947677^1,2	C	--	143435192(+)	`CCCGGC/TGATTC`	2	H R	mis¹		1		EU	593
rs74599724^1,2	F,	--	143435773(+)	`CCCAAC/AACTTT`	1	--	int¹		1		NA	120
rs74300794^1,2		--	143435874(+)	`TGGTCC/TCAACA`	1	--	int¹		0	--	--	--	--
rs727713^1,2	C,F,A,H,	--	143437174(+)	`GAGACA/GGCGTT`	1	--	int¹		21		NS EA NA WA	2326

HapMap Linkage Disequilibrium report for NOBOX (144094333 - 144107320 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for NOBOX
2 CNVs: 4573 3708
1 Inversion: 37284
Human Gene Mutation Database (HGMD): NOBOX

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOBOX

DNA2.0 Custom Variant and Variant Library Synthesis for NOBOX

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NOBOX for disorders           About GeneDecksing

OMIM gene information: 610934
OMIM disorders: 611548
UniProtKB/Swiss-Prot: NOBOX_HUMAN, O60393

Defects in NOBOX are the cause of premature ovarian failure type 5 (POF5) [MIM:611548]. An ovarian disorder

defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or

amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol

5 diseases for NOBOX: About MalaCards

premature ovarian failure premature ovarian failure 5 oophoritis ovarian cyst

amenorrhea

1 disease from the University of Copenhagen DISEASES database for NOBOX:

Premature ovarian failure

Human Genome Epidemiology (HuGE) Navigator: NOBOX (3 documents)

Export disorders for NOBOX gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NOBOX gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with NOBOX)

Utopia: connect your pdf to the dynamic
world of online information

cDNA cloning and expression of the human NOBOX gene in oocytes and ovarian follicles. (PubMed id 16597639)^{1, 2, 3} Huntriss J.... Picton H.M. (2006)
Novel NOBOX loss-of-function mutations account for 6.2% of cases in a large primary ovarian insufficiency cohort. (PubMed id 21837770)^{1, 2} Bouilly J.... Binart N. (2011)
NOBOX homeobox mutation causes premature ovarian failure. (PubMed id 17701902)^{1, 2} Qin Y.... Rajkovic A. (2007)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes. (PubMed id 11804785)^{1, 3} Suzumori N....Rajkovic A. (2002)
Clinical, biological and genetic analysis of prepuber tal isolated ovarian cyst in 11 girls. (PubMed id 20593028)¹ Brauner R....McElreavey K. (2010)
Premature ovarian failure and gene polymorphisms. (PubMed id 19610175)¹ van Dooren M.F....Oldenburg R.A. (2009)
A genome-wide linkage scan in a Dutch family identifi es a premature ovarian failure susceptibility locus. (PubMed id 18689850)¹ Oldenburg R.A....Bertoli-Avella A.M. (2008)
A 12Mb deletion at 7q33-q35 associated with autism sp ectrum disorders and primary amenorrhea. (PubMed id 18675947)¹ Rossi E....Zuffardi O. (2008)
Mutation analysis of NOBOX homeodomain in chinese women with premature ovarian failure. (PubMed id 18930203)¹ Qin Y....Chen Z.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 135935	HGNC: 22448	Ensembl:ENSG00000106410	euGenes: HUgn135935	ECgene: NOBOX
H-InvDB: NOBOX

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NOBOX	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NOBOX gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NOBOX gene:
Search GeneIP for patents involving NOBOX

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


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	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NOBOX		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NOBOX
	OriGene Protein Over-expression Lysate for NOBOX		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for NOBOX		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NOBOX		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NOBOX
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for NOBOX		OriGene Custom Protein Services for NOBOX
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NOBOX
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NOBOX
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOBOX
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOBOX
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOBOX
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOBOX

	GenScript Custom Purified and Recombinant Proteins Services for NOBOX		GenScript cDNA clones with any tag delivered in your preferred vector for NOBOX
	GenScript Custom Assay Services for NOBOX		GenScript Custom Superior Antibodies Services for NOBOX
	GenScript Custom overexpressing Cell Line Services for NOBOX		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in NOBOX promoter
	Search Chromatin IP Primers for NOBOX
	RT² qPCR Primer Assay in human, mouse, rat NOBOX
	Search GNC Networks for NOBOX
	SABiosciences Custom PCR Arrays for NOBOX

Search Tocris compounds for NOBOX

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	NOBOX antibodies

	Search for Antibodies for NOBOX at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for NOBOX
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

NOBOX Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for NOBOX

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOBOX

	Browse SwitchGear 3'UTR luciferase reporter plasmids for NOBOX
	Browse SwitchGear Promoter luciferase reporter plasmids for NOBOX

Search ThermoFisher Antibodies for NOBOX

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOBOX

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes NOBOX gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

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NOBOX Gene

NOBOX oogenesis homeobox

Aliases
for NOBOX gene

Summaries
for NOBOX gene

Genomic Views
for NOBOX gene

Proteins
for NOBOX gene

Protein Domains /
Families
for NOBOX gene

Function
for NOBOX gene

Pathways & Interactions
for NOBOX gene

Drugs & Compounds
for NOBOX gene

Transcripts
for NOBOX gene

Expression
for NOBOX gene

Orthologs
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Paralogs
for NOBOX gene

Genomic Variants
for NOBOX gene

Disorders / Diseases
for NOBOX gene

Publications
for NOBOX gene

External Searches for NOBOX gene

Genome Databases showing NOBOX gene

Other Databases showing NOBOX gene

Specialized Databases showing NOBOX gene

Intellectual Property
for NOBOX gene

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for NOBOX gene

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Advanced Search

Export list of displayed genes

NOBOX Gene

NOBOX oogenesis homeobox

Aliasesfor NOBOX gene

Summariesfor NOBOX gene

Genomic Viewsfor NOBOX gene

Proteinsfor NOBOX gene

Protein Domains /Familiesfor NOBOX gene

Functionfor NOBOX gene

Pathways & Interactionsfor NOBOX gene

Drugs & Compoundsfor NOBOX gene

Transcriptsfor NOBOX gene

Expression for NOBOX gene

Orthologsfor NOBOX gene

Paralogsfor NOBOX gene

Genomic Variantsfor NOBOX gene

Disorders / Diseasesfor NOBOX gene

Publicationsfor NOBOX gene

External Searches for NOBOX gene

Genome Databases showing NOBOX gene

Other Databases showing NOBOX gene

Specialized Databases showing NOBOX gene

Intellectual Propertyfor NOBOX gene

Productsfor NOBOX gene

View Random Gene

Aliases
for NOBOX gene

Summaries
for NOBOX gene

Genomic Views
for NOBOX gene

Proteins
for NOBOX gene

Protein Domains /
Families
for NOBOX gene

Function
for NOBOX gene

Pathways & Interactions
for NOBOX gene

Drugs & Compounds
for NOBOX gene

Transcripts
for NOBOX gene

Expression
for NOBOX gene

Orthologs
for NOBOX gene

Paralogs
for NOBOX gene

Genomic Variants
for NOBOX gene

Disorders / Diseases
for NOBOX gene

Publications
for NOBOX gene

Intellectual Property
for NOBOX gene

Products
for NOBOX gene