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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NOB1 Gene

protein-coding   GIFtS: 57
GCID: GC16M069775

NIN1/RPN12 Binding Protein 1 Homolog (S. Cerevisiae)

(Previous name: PSMD8 binding protein 1)
(Previous symbol: PSMD8BP1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NIN1/RPN12 Binding Protein 1 Homolog (S. Cerevisiae)1 2     NOB1P2 3
PSMD8BP11 2 3     ART-42
PSMD8 Binding Protein 11 2     MST1582
Nin One Binding Protein1 2     Adenocarcinoma Antigen Recognized By T Lymphocytes 42
Phosphorylation Regulatory Protein HP-102 3     RNA-Binding Protein NOB12
Protein ART-42 3     ART43

External Ids:    HGNC: 295401   Entrez Gene: 289872   Ensembl: ENSG000001411017   OMIM: 6135865   UniProtKB: Q9ULX33   

Export aliases for NOB1 gene to outside databases

Previous GC identifers: GC16M068334 GC16M055654


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NOB1 Gene:
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved
in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript
into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1
is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate
at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 (PubMed 19706509)).(supplied by
OMIM, Nov 2010)

GeneCards Summary for NOB1 Gene: 
NOB1 (NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with NOB1 include adenocarcinoma, and thymoma. GO annotations related to this gene include metal ion binding.

UniProtKB/Swiss-Prot: NOB1_HUMAN, Q9ULX3
Function: May play a role in mRNA degradation

Gene Wiki entry for NOB1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NOB1 gene promoter:
         NF-AT2   GATA-3   AP-1   NF-AT3   NF-AT1   NF-AT   GATA-2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNOB1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NOB1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NOB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.3   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

NOB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOB1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M069775:  view genomic region     (about GC identifiers)

Start:
69,775,770 bp from pter      End:
69,788,843 bp from pter
Size:
13,074 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NOB1_HUMAN, Q9ULX3 (See protein sequence)
Recommended Name: RNA-binding protein NOB1  
Size: 412 amino acids; 46675 Da
Subunit: Interacts with UPF2 (Probable)
Subcellular location: Nucleus
Sequence caution: Sequence=AAQ13705.1; Type=Frameshift; Positions=393; Sequence=BAA91473.1; Type=Frameshift;
Positions=87;
Secondary accessions: Q7L6B7 Q7M4M4 Q7Z4B5 Q9NWB0

Explore the universe of human proteins at neXtProt for NOB1: NX_Q9ULX3

Explore proteomics data for NOB1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9ULX3

  • NOB1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NOB1 Protein Expression
    REFSEQ proteins: NP_054781.1  
    ENSEMBL proteins: 
     ENSP00000268802   ENSP00000457760   ENSP00000456710  

    Human Recombinant Protein Products for NOB1: 
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    OriGene Protein Over-expression Lysate for NOB1
    OriGene MassSpec for NOB1 
    OriGene Custom Protein Services for NOB1
    GenScript Custom Purified and Recombinant Proteins Services for NOB1
    Novus Biologicals NOB1 Proteins
    Novus Biologicals NOB1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NOB1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    NOB1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for NOB1 
    Cloud-Clone Corp. CLIAs for NOB1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR014881 NOB1_Zn-bd
     IPR006596 PINc_nuc-bd
     IPR017117 D-site_20S_pre-rRNA_nuclease

    Graphical View of Domain Structure for InterPro Entry Q9ULX3

    ProtoNet protein and cluster: Q9ULX3

    2 Blocks protein domains:
    IPB002110 Ankyrin repeat signature
    IPB006596 Nucleotide binding protein


    UniProtKB/Swiss-Prot: NOB1_HUMAN, Q9ULX3
    Similarity: Belongs to the NOB1 family
    Similarity: Contains 1 PINc domain


    NOB1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NOB1_HUMAN, Q9ULX3
    Function: May play a role in mRNA degradation

         Genatlas biochemistry entry for NOB1:
    new organization associated with HLA-B,gene NOB1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    NOB1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NOB1:
     Decreased viability of wild-ty  Increased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NOB1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NOB1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NOB1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NOB1 

    miRNA
    Products:
        
    miRTarBase miRNAs that target NOB1:
    hsa-mir-16 (MIRT005263)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOB1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate NOB1:
    hsa-miR-3128
    SwitchGear 3'UTR luciferase reporter plasmidNOB1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NOB1
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    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of NOB1 

    Cell Line
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    Search LifeMap BioReagents cell lines for NOB1
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOB1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NOB1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for NOB1):
        Ribosome biogenesis in eukaryotes


    NOB1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NOB1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/97 Interacting proteins for NOB1 (Q9ULX31, 3 ENSP000002688024) via UniProtKB, MINT, STRING, and/or I2D (see all 97)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NOB1

    Search CenterWatch for drugs/clinical trials and news about NOB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NOB1 gene: 
    NM_014062.2  

    Unigene Cluster for NOB1:

    NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
    Hs.271695  [show with all ESTs]
    Unigene Representative Sequence: AK126196
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000268802(uc002exs.3) ENST00000569871 ENST00000564620 ENST00000561677
    ENST00000563055 ENST00000562416
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NOB1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate NOB1:
    hsa-miR-3128
    SwitchGear 3'UTR luciferase reporter plasmidNOB1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NOB1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NOB1
    Clone
    Products:
         
    OriGene clones in human, mouse for NOB1 (see all 7)
    OriGene ORF clones in mouse, rat for NOB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NOB1 (NM_014062)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NOB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NOB1
    Sirion Biotech Customized lentivirus for stable overexpression of NOB1 
                         Customized lentivirus expression plasmids for stable overexpression of NOB1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NOB1
    OriGene qSTAR qPCR primer pairs in human, mouse for NOB1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NOB1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NOB1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NOB1

    Additional mRNA sequence: 

    AB026125.1 AF190161.1 AK001028.1 AK126196.1 AK314307.1 AY487344.1 BC000050.2 BC064630.1 
    NR_074074.1 

    13 DOTS entries:

    DT.80100673  DT.120678734  DT.101984838  DT.97780613  DT.100818147  DT.92446033  DT.100818156  DT.97864342 
    DT.120678748  DT.92035008  DT.95358340  DT.99990128  DT.92446041 

    24/410 AceView cDNA sequences (see all 410):

    NM_014062 AW954290 AA375932 AW302470 BX461581 W17088 CR595764 AI344516 
    BX443623 T16649 BQ217654 BM724762 AI609078 BQ880252 BI820352 CR603829 
    AA577628 CB145536 AI074178 AA377635 CB112995 BU556843 BG742530 BM763643 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NOB1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9
    SP1:                                                  -                     
    SP2:                                                                        
    SP3:                                                                        


    ECgene alternative splicing isoforms for NOB1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NOB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTTAGATT
    NOB1 Expression
    About this image


    See NOB1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NOB1

    SOURCE GeneReport for Unigene cluster: Hs.271695

    UniProtKB/Swiss-Prot: NOB1_HUMAN, Q9ULX3
    Tissue specificity: Detected in liver, lung, placenta, endothelial cells and spleen

        SABiosciences Custom PCR Arrays for NOB1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NOB1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NOB1 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nob11 , 5 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)1, 5 86.73(n)1
    91.04(a)1
      8 (54.12 cM)5
    676191  NM_026277.31  NP_080553.11 
     1074124865 
    chicken
    (Gallus gallus)
    Aves NOB11 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 69.66(n)
    67.72(a)
      415867  XM_414227.3  XP_414227.2 
    lizard
    (Anolis carolinensis)
    Reptilia NOB16
    Uncharacterized protein
    58(a)
    1 ↔ 1
    GL343643.1(158729-173007)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3987012 nin one binding protein 75.14(n)    AY341887.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc27e052 Danio rerio cDNA clone IMAGE6795459, partial cds 75.16(n)    BC056558.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG29721 CG2972 51.26(n)
    40.95(a)
      31943  NM_132375.2  NP_572603.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y54E10BR.41 Protein Y54E10BR.4 49.71(n)
    39.31(a)
      171874  NM_058689.2  NP_491090.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NOB1(YOR056C)4
    NOB11
    Essential nuclear protein involved in proteasome maturation more4
    Nob1p1
    42.96(n)1
    32.47(a)1
      15(431626-430247)4
    8542211, 4  NP_014699.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G411901 RNA-binding protein NOB1 49.88(n)
    40.43(a)
      834121  NM_123484.2  NP_198935.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01147001 hypothetical protein 51.36(n)
    45.91(a)
      4328064  NM_001052205.1  NP_001045670.1 


    ENSEMBL Gene Tree for NOB1 (if available)
    TreeFam Gene Tree for NOB1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NOB1 gene

    NOB1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NOB1
    PGOHUM00000246087


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/420 SNPs in NOB1 are shown (see all 420)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1867931011,2
    --69775357(+) CTTACC/TTCTTG 2 -- ds50010--------
    rs99385521,2
    C,F,H--69775364(+) CTTGTA/GGCTCA 2 -- ds50018Minor allele frequency- G:0.00NS EA NA 888
    rs1452894381,2
    --69775383(+) CGAAAA/TAACAG 2 -- ds50010--------
    rs1509952851,2
    C--69775392(+) AGCAGC/TCGTAC 2 -- ds50010--------
    rs1915861121,2
    --69775466(+) TCATAA/GCTCTT 2 -- ds50010--------
    rs1395699131,2
    --69775473(+) TCTTCA/GCAATG 2 -- ds50010--------
    rs172994781,2
    C,F,H--69775500(+) AAGAAC/TGAACT 2 -- ds500127Minor allele frequency- T:0.11NA EA NS 2712
    rs1831521861,2
    C--69775620(+) CTAGAC/GGACTC 2 -- ds50010--------
    rs1864357931,2
    --69775629(+) TCATAC/GTTTGT 2 -- ds50010--------
    rs169591431,2
    C,F--69775638(+) GTGACT/CGTGTG 2 -- ds50013Minor allele frequency- C:0.01NA 142

    HapMap Linkage Disequilibrium report for NOB1 (69775770 - 69788843 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NOB1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv524364CNV Loss19592680
    nsv906823CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NOB1
    DNA2.0 Custom Variant and Variant Library Synthesis for NOB1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613586    OMIM disorders: --

    6 diseases for NOB1:    About MalaCards
    adenocarcinoma    thymoma    endotheliitis    gastric cancer
    ovarian cancer    hepatocellular carcinoma

    1 disease from the University of Copenhagen DISEASES database for NOB1:
    Thymoma

    NOB1 for disorders           About GeneDecksing


    Export disorders for NOB1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NOB1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with NOB1)
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    world of online information

    1. Cloning, expression and characterization of the human NOB1 gene. (PubMed id 16172919)1, 2, 3, 9 Zhang Y....Zhao S. (2005)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A protein interaction framework for human mRNA degradation. (PubMed id 15231747)1, 2 Lehner B. and Sanderson C.M. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli. (PubMed id 1791827)1, 2 Daniele A.... Magnani M. (1991)
    7. The von Hippel-Lindau protein pVHL inhibits ribosome b iogenesis and protein synthesis. (PubMed id 23612971)1 Zhao W.T....Fang J. (2013)
    8. [Expression of NOB1 and its significance in colorectal cancer]. (PubMed id 22445998)1 Wu D.P. and He X.W. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. Downregulation of NIN/RPN12 binding protein inhibit th e growth of human hepatocellular carcinoma cells. (PubMed id 21573803)1 Lu Z....Lu Q. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28987 HGNC: 29540 AceView: NOB1P Ensembl:ENSG00000141101 euGenes: HUgn28987
    ECgene: NOB1 Kegg: 28987 H-InvDB: NOB1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NOB1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NOB1 gene:
    Search GeneIP for patents involving NOB1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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