Aliases for NOA1 Gene
External Ids for NOA1 Gene
Previous HGNC Symbols for NOA1 Gene
Previous GeneCards Identifiers for NOA1 Gene
The protein encoded by this gene is a nuclear-encoded GTPase that functions in the mitochondrion. Upon translation, this protein is imported into the nucleus and then into the nucleolus before being exported to the mitochondrion. The encoded protein is required for oxygen-dependent regulation of mitochondrial respiratory complexes and for mitochondrial protein synthesis. [provided by RefSeq, Dec 2015]
GeneCards Summary for NOA1 Gene
NOA1 (Nitric Oxide Associated 1) is a Protein Coding gene. Diseases associated with NOA1 include Sarcomatosis and Macular Degeneration, Age-Related, 1. GO annotations related to this gene include poly(A) RNA binding and GTPase activity.
UniProtKB/Swiss-Prot for NOA1 Gene
Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP.