NNT Gene
protein-coding GIFtS: 61
GCID: GC05P043638
|
|
nicotinamide nucleotide transhydrogenase
| |
Aliases
for NNT gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nicotinamide Nucleotide Transhydrogenase1 2 3 | | Pyridine Nucleotide Transhydrogenase2 3 | | EC 1.6.1.23 8 | | GCCD42 | | NAD(P) Transhydrogenase, Mitochondrial2 |
Export aliases for NNT gene to outside databasesPrevious GC identifers: GC05P043918 GC05P044779 GC05P043602 GC05P043648 |
Summaries
for NNT gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NNT:
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer betweenNAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiologicalconditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. Theresulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants,encoding the same protein, have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423Function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as aproton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland
Gene Wiki entry for NNT
|
Genomic Views
for NNT gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NNT gene promoter:
POU2F1 CP2 POU2F1a Ik-3 LCR-F1 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NNT
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NNT |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p12 Ensembl cytogenetic band: 5p12 HGNC cytogenetic band: 5p12NNT Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P043638: view genomic region
(about GC identifiers)
Start:
|
43,602,791 bp from pter |
End:
|
43,707,507 bp from pter |
Size:
|
104,717 bases |
Orientation:
|
plus strand |
|
Proteins
for NNT gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423 (See
protein sequence)Recommended Name: NAD(P) transhydrogenase, mitochondrial precursor Size: 1086 amino acids; 113896 Da
Subunit: Homodimer (By similarity)
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side (Potential)
3 PDB 3D structures from  and Proteopedia  for NNT:1DJL (3D)
1PT9 (3D)
1U31 (3D)
Secondary accessions: Q16796 Q2TB60 Q8N3V4Explore the universe of human proteins at neXtProt for NNT: NX_Q13423
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13423
4/11 DME Specific Peptides for NNT (Q13423) (see all 11)
NNT Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_036475.3 NP_892022.2
ENSEMBL proteins: ENSP00000427670 ENSP00000421886 ENSP00000264663 ENSP00000343873 ENSP00000426343 ENSP00000425542 ENSP00000421674 ENSP00000424782 Reactome Protein details: Q13423
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
NNT for ontologies About GeneDecksing
NNT Antibody Products:
Assay Products for NNT: |
Protein
Domains /
Families
for NNT gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NNT for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q13423ProtoNet protein and cluster: Q13423 2 Blocks protein families: IPB004003 NAD(P) transhydrogenase IPB008143 Alanine dehydrogenase/PNT
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423Similarity: In the N-terminal section; belongs to the AlaDH/PNT familySimilarity: In the C-terminal section; belongs to the PNT beta subunit family |
Function
for NNT gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423Function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as aproton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal glandCatalytic activity: NADPH + NAD(+) = NADP(+) + NADH Genatlas biochemistry entry for NNT:nicotinamide nucleotide transhydrogenase,integral protein of the inner mitochondrial membrane,proton-pumping,orthologto bovin and mouse enzymes
Enzyme Number (IUBMB): EC 1.6.1.21 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NNT (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NNT (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): NNT (NM_001126133) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NNT | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NNT |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNT |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
NNT for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for NNT:
Animal Models:
3 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Nnt):
NNT for phenotypes About GeneDecksing
|
Pathways & Interactions
for NNT gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | NAD metabolism | | | 2 | Metabolism | | | 3 | NAD phosphorylation and dephosphorylation | | | 4 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 5 | TCA cycle II (eukaryotic) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for NNT
1  GeneGo (Thomson Reuters) Pathway for NNT
1  BioSystems Pathway for NNT
4 
Reactome Pathways for NNT
2 
Kegg Pathways (Kegg details for NNT):
NNT for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NNT
STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)
5/19 Interacting proteins for NNT (Q134233 ENSP000002646634) via UniProtKB, MINT, STRING, and/or I2D (see all 19)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
NNT for ontologies About GeneDecksing
|
Drugs & Compounds
for NNT gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NNT for compounds About GeneDecksing
 Browse Tocris compounds for NNT
4 HMDB Compounds for NNT About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| NAD | 3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28) | 53-84-9 | -- | | NADH | 1,4-Dihydronicotinamide adenine dinucleotide (see all 17) | 58-68-4 | -- | | NADP | Adenine-nicotinamide dinucleotide phosphate (see all 18) | 53-59-8 | -- | | NADPH | 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23) | 53-57-6 | -- |
3 DrugBank Compounds for NNT About this table
6 Novoseek chemical compound relationships for NNT gene About this table
Search CenterWatch for drugs/clinical trials and news about NNT / NNTM
|
Transcripts
for NNT gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NNT gene (2 alternative transcripts): NM_012343.3 NM_182977.2 Unigene Cluster for NNT: Nicotinamide nucleotide transhydrogenase Hs.482043 [show with all ESTs]Unigene Representative Sequence: NM_01234310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000505678 ENST00000512422 ENST00000264663(uc003joe.3 uc003jof.3)
ENST00000344920 ENST00000512996 ENST00000515208 ENST00000506893 ENST00000503651
ENST00000513390 ENST00000503059
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NNT (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NNT (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): NNT (NM_001126133) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NNT | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NNT |
Additional cDNA sequence: AK096668.1 AK297558.1 AK299622.1 AL831822.2 BC032370.1 BC064402.1 BC110543.1 BC110544.1 U40490.1 Z50101.1 14 DOTS entries: DT.100789273 DT.452955 DT.216226 DT.100742601 DT.121640813 DT.100041792 DT.102835370 DT.75145435 DT.75186203 DT.101962524 DT.120830623 DT.91772466 DT.95276901 DT.91772469 24/264 AceView cDNA sequences (see all 264): AW001598 AI583593 AL602040 AW611956 CD107845 F07388 AU132236 BU164990 AI983659 CB163975 BM968126 AI435850 AL045135 AI337362 AI818518 AW771969 BQ639542 AI371022 AL525737 AI984379 BC064402 BU935218 BE086894 BG569411
GeneLoc Exon Structure
|
Expression
for NNT gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NNT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NNT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NNT
SOURCE GeneReport for Unigene cluster: Hs.482043
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423Tissue specificity: Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid andadipose tissues
SABiosciences Custom PCR Arrays for NNT
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NNT
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NNT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NNT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NNT | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNT |
Orthologs
for NNT gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NNT gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Nnt5 |
nicotinamide nucleotide transhydrogenase |
-- |
|
13 (67.21 cM) 119335448 |
chicken
(Gallus gallus) |
Aves |
NNT1 |
nicotinamide nucleotide transhydrogenase |
78.53(n)
88.66(a) |
|
427196 XM_003642936.1 XP_003642984.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NNT6 |
-- |
89(a) |
1 ↔ 1 |
2(5941881-5981542) |
zebrafish
(Danio rerio) |
Actinopterygii |
CF997412.12 |
-- |
76.25(n) |
|
387008 CF997412.1 |
mosquito
(Anopheles gambiae) |
Insecta |
AgaP_AGAP0031671 |
AGAP003167-PA |
61.55(n)
66.93(a) |
|
1273837 XM_312859.4 XP_312859.4 |
worm
(Caenorhabditis elegans) |
Secernentea |
nnt-11 , 3 |
NAD(P) transhydrogenase, mitochondrial3
Protein NNT-11 |
61(a)3
59.75(n)1
63.54(a)1 |
|
X(6157591-6162719)3
1808841 NM_076627.21 NP_509028.11 |
ENSEMBL Gene Tree for NNT (if available)
TreeFam Gene Tree for NNT (if available) |
Paralogs
for NNT gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NNT gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NNT (43602791 - 43707507 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NNT: --
Human Gene Mutation Database (HGMD): NNT
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NNT |
|
Disorders
/ Diseases
for NNT gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NNT for disorders About GeneDecksing
OMIM gene information: 607878
OMIM disorders: --
UniProtKB/Swiss-Prot: NNTM_HUMAN, Q13423
Defects in NNT are the cause of glucocorticoid deficiency type 4 (GCCD4) [MIM:614736]. A rare, potentiallylethal, autosomal recessive disorder characterized by resistance to ACTH action on the adrenal cortex, adrenalinsufficiency and an inability of the adrenal cortex to produce cortisol. It usually presents in the neonatal periodor in early childhood with episodes of hypoglycemia and other symptoms related to cortisol deficiency, includingfailure to thrive, recurrent illnesses or infections, convulsions, and shock. In a small number of patientshypoglycemia can be sufficiently severe and persistent that it leads to serious long-term neurological damage ordeath. The diagnosis is readily confirmed with a low plasma cortisol measurement in the presence of an elevated ACTHlevel, and normal aldosterone and plasma renin measurements
5  diseases for NNT: About MalaCardsglucose intolerance tuberculosis obesity malaria
mycobacterium tuberculosis
1 disease from the University of Copenhagen DISEASES database for NNT:Glucose intolerance 2 Novoseek disease relationships for NNT gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glucose intolerance |
55.3 |
3 |
16766189 (1), 19815054 (1) |
| tuberculosis |
7.29 |
2 |
9661660 (1), 8439307 (1) |
Human Genome Epidemiology (HuGE) Navigator: NNT (1 document)
Export disorders for NNT gene to outside databases
|
Publications
for NNT gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NNT gene, integrated from 9 sources (see all 50):
(articles sorted by number of sources associating them with NNT) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase. (PubMed id 9524818)1, 2, 3, 9 Zieger B. and Ware J. (1997)
- The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse. (PubMed id 8616157)1, 2, 9 Lagberg E.M.... Rydstrom J. (1996)
- Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency. (PubMed id 22634753)1, 2 Meimaridou E.... Metherell L.A. (2012)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria. (PubMed id 10673423)1, 2 White S.A....Jackson J.B. (2000)
- Mapping of the rat and mouse nicotinamide nucleotide transhydrogenase gene. (PubMed id 9271681)1, 3 Arkblad E.L....Rydstrom J. (1997)
- Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol. (PubMed id 8951041)1, 9 Forsmark-Andree P....Ernster L. (1996)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for NNT gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NNT gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NNT gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NNT gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NNT | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NNT gene:
Search GeneIP for patents involving NNT
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NNT gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NNT | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NNT | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NNT | | | OriGene Protein Over-expression Lysate for NNT | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NNT | | OriGene 3'-UTR Clone for NNT | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NNT | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NNT | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NNT | | OriGene Custom Protein Services for NNT | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NNT | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NNT | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NNT | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NNT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NNT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NNT |
| |
 |  |  |  | |
| | | | Search Tocris compounds for NNT |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | NNT Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNT |
|  |  |  | | | | Search ThermoFisher Antibodies for NNT |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NNT |
|
|
|
|
