NNO1 Locus
genetic locus GIFtS: 11
GCID: GC11U990205
|
|
Nanophthalmos 1
| |
Aliases
for NNO1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
TryGeneCards Plus |
| Aliases |
|---|
| Nanophthalmos 11 2 |
Export aliases for NNO1 gene to outside databases |
Summaries
for NNO1 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
TryGeneCards Plus |
GeneCards Summary for NNO1 Gene:
NNO1 (nanophthalmos 1) is a genetic locus. Diseases associated with NNO1 include nanophthalmos-1, and hyperopia.
|
Genomic Views
for NNO1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | Regulatory elements:
 Search for regulatory transcription factor binding sites for NNO1
Other transcription factors
Search Chromatin IP Primers for NNO1
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NNO1 |
Genomic Location:
Chromosome:11
Entrez Gene cytogenetic band: 11p13 HGNC cytogenetic band: 11p13GeneLoc information about chromosome 11 |
Proteins
for NNO1 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
TryGeneCards Plus |
UniProtKB: --
|
Domains /
Families
for NNO1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | -- |
Function
for NNO1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
TryGeneCards Plus |
Animal Models:
Inhib. RNA
Products: |  | Browse OriGene RNAi
| | | Predesigned siRNA for gene silencing in human, mouse, rat NNO1 |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for NNO1 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for NNO1  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNO1 |
Localization
for NNO1 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
TryGeneCards Plus | -- |
Pathways & Interactions
for NNO1 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
TryGeneCards Plus |
Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NNO1
Interactions:
Search GeneGlobe Interaction Network for NNO1
|
Drugs & Compounds
for NNO1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
TryGeneCards Plus |
 Browse compounds at ApexBio
 Browse Tocris compounds for NNO1
|
Transcripts
for NNO1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
About This Section
TryGeneCards Plus |
Inhib. RNA
Products: | | Browse OriGene RNAi
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat NNO1 |
|
Expression
for NNO1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
TryGeneCards Plus |
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
NNO1 Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  --
Custom PCR Arrays for NNO1
Primer
Products: | | Browse OriGene qPCR
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat NNO1 | | | QuantiTect SYBR Green Assays in human, mouse, rat NNO1 | | | QuantiFast Probe-based Assays in human, mouse, rat NNO1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNO1 |
Orthologs
for NNO1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
TryGeneCards Plus |
--
|
Paralogs
for NNO1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | -- |
Genomic Variants
for NNO1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
TryGeneCards Plus | | | Site Specific Mutation Identification with PCR Assays |
|
Disorders
/ Diseases
for NNO1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
TryGeneCards Plus |
OMIM gene information: 600165
OMIM disorders: --
3  diseases for NNO1:
About MalaCardsnanophthalmos-1 hyperopia glaucoma
NNO1 for disorders About GeneDecksing
Export disorders for NNO1 gene to outside databases
|
Publications
for NNO1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
TryGeneCards Plus |
PubMed article for NNO1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NNO1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Autosomal dominant nanophthalmos (NNO1) with high hyperopia and angle-closure glaucoma maps to chromosome 11. (PubMed id 9792868)1, 3 Othman M.I....Richards J.E. (Am. J. Hum. Genet. 1998)
|
External Searches for NNO1 gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
TryGeneCards Plus |
|
Genome Databases showing NNO1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
TryGeneCards Plus |
|
Other Databases showing NNO1 gene
(According to HUGE)
About This Section
TryGeneCards Plus | -- |
Specialized Databases showing NNO1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
TryGeneCards Plus |
| Name | Description |
| PharmGKB entry for NNO1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
TryGeneCards Plus | Patent Information for NNO1 gene:
Search GeneIP for patents involving NNO1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NNO1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
TryGeneCards Plus |
 | |
 |
| | | | |
 |
 |
|  | Block miRNA regulation of human, mouse, rat NNO1 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing NNO1 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NNO1 | | Predesigned siRNA for gene silencing in human, mouse, rat NNO1 | | | QuantiFast Probe-based Assays in human, mouse, rat NNO1 | | QuantiTect SYBR Green Assays in human, mouse, rat NNO1 | | | Custom PCR Arrays for NNO1 | | Search Chromatin IP Primers for NNO1 | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NNO1 | | Search GeneGlobe Interaction Network for NNO1 | | | Search Regulatory tfbs for NNO1 |
| |
 |  |  |  | |
| | | Search Tocris compounds for NNO1 |
| | |  |  |  |
 | | | | |
 |
 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NNO1 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for NNO1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NNO1 |
| | |  |  | | |
|
|
|
GeneCards Homepage -
Last full update: 7 May 2014 -
Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014
View Random Gene
|
Category
|
|
|
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2014
, Weizmann Institute of Science. All Rights Reserved.
Version: 3.12.142 28 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4
|
