External Ids for NMU Gene
Previous GeneCards Identifiers for NMU Gene
This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]
GeneCards Summary for NMU Gene
NMU (Neuromedin U) is a Protein Coding gene. Diseases associated with NMU include Trachea Leiomyoma and Squamous Cell Papilloma. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include receptor binding and neuromedin U receptor binding.
UniProtKB/Swiss-Prot for NMU Gene
Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.