NMT1 Gene
protein-coding GIFtS: 63
GCID: GC17P043139
|
|
N-myristoyltransferase 1
| |
Aliases
for NMT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| N-Myristoyltransferase 11 2 | | NMT 12 3 | | NMT1 2 3 5 | | EC 2.3.1.973 8 | | Myristoyl-CoA:Protein N-Myristoyltransferase 12 3 | | Alternative, Short Form NMT-S2 | | Peptide N-Myristoyltransferase 12 3 | | Glycylpeptide N-Tetradecanoyltransferase 12 | | Type I N-Myristoyltransferase2 3 | | Long Form, NMT-L2 |
Export aliases for NMT1 gene to outside databasesPrevious GC identifers: GC17M042667 GC17M045252 GC17P043149 GC17P043613 GC17P040494 GC17P038903 |
Summaries
for NMT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NMT1:
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminalglycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97)catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is requiredfor full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of thesignal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 (PubMed1570339)).(supplied by OMIM, Nov 2008)
UniProtKB/Swiss-Prot: NMT1_HUMAN, P30419Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins
Gene Wiki entry for NMT1 (N-myristoyltransferase 1)
|
Genomic Views
for NMT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NMT1 gene promoter:
c-Fos AP-1 MAZR IRF-1 CBF-C CBF-B CBF-A Cart-1 c-Jun CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for NMT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31NMT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P043139: view genomic region
(about GC identifiers)
Start:
|
43,128,978 bp from pter |
End:
|
43,186,384 bp from pter |
Size:
|
57,407 bases |
Orientation:
|
plus strand |
|
Proteins
for NMT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NMT1_HUMAN, P30419 (See
protein sequence)Recommended Name: Glycylpeptide N-tetradecanoyltransferase 1 Size: 496 amino acids; 56806 Da
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAC09294.1; Type=Erroneous initiation;
5 PDB 3D structures from  and Proteopedia  for NMT1:1RXT (3D)
3IU1 (3D)
3IU2 (3D)
3IWE (3D)
3JTK (3D)
Secondary accessions: A8K7C1 Q9UE09Alternative splicing: 2 isoforms: P30419-1 P30419-2 Explore the universe of human proteins at neXtProt for NMT1: NX_P30419
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P30419
4/21 DME Specific Peptides for NMT1 (P30419) (see all 21)
NMT1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_066565.1
ENSEMBL proteins: ENSP00000468424 ENSP00000439263 ENSP00000466777 ENSP00000466827 ENSP00000258960 Reactome Protein details: P30419
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
NMT1 for ontologies About GeneDecksing
NMT1 Antibody Products:
Assay Products for NMT1: |
Protein
Domains /
Families
for NMT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NMT1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P30419ProtoNet protein and cluster: P30419 1 Blocks protein family: IPB000903 Myristoyl-CoA:protein N-myristoyltransferase
UniProtKB/Swiss-Prot: NMT1_HUMAN, P30419Similarity: Belongs to the NMT family |
Function
for NMT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NMT1_HUMAN, P30419Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteinsCatalytic activity: Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptideEnzyme Number (IUBMB): EC 2.3.1.971 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NMT1 (NM_001379) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NMT1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMT1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMT1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003824 | catalytic activity |
TAS | 9506952 | | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity |
IEA | -- | | GO:0019107 | myristoyltransferase activity |
-- | -- |
NMT1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for NMT1:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Nmt1):
NMT1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NMT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Late Phase of HIV Life Cycle | | | 2 | Activation, myristolyation of BID and translocation to mitochondria | | | 3 | HIV Infection | | | 4 | Disease | | | 5 | Ubiquitinated Orc1 is degraded by the proteasome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 
Reactome Pathways for NMT1 (see all 7)
NMT1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NMT1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/37 Interacting proteins for NMT1 (P304192, 3 ENSP000002589604) via UniProtKB, MINT, STRING, and/or I2D (see all 37)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001701 | in utero embryonic development |
-- | -- | | GO:0006498 | N-terminal protein lipidation |
NAS | -- | | GO:0006499 | N-terminal protein myristoylation |
NAS | -- | | GO:0006915 | apoptotic process |
TAS | -- | | GO:0008633 | activation of pro-apoptotic gene products |
-- | -- |
NMT1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NMT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NMT1 for compounds About GeneDecksing
 Compounds for NMT1 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Tris DBA | N-myristoyltransferase-1 inhibitor; antiproliferative | [52522-40-4] |
2 HMDB Compounds for NMT1 About this table
1 DrugBank Compound for NMT1 About this table
10/12 Novoseek chemical compound relationships for NMT1 gene (see all 12) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| myristoyl-coa |
94.2 |
12 |
9174411 (1), 2197361 (1), 2271666 (1), 17518043 (1) (see all 6) |
| myristic acid |
89.5 |
17 |
2197361 (1), 2271666 (1), 9506952 (1), 11139338 (1) (see all 15) |
| 2-hydroxymyristic acid |
84.4 |
2 |
8103677 (1) |
| acyl-coa |
65.4 |
15 |
2026598 (2), 2271666 (2), 1559967 (2), 9174411 (1) (see all 6) |
| anti-fungal |
46.8 |
5 |
9174411 (1), 17518043 (1), 1559967 (1), 9043113 (1) |
| fatty acid |
40.4 |
9 |
2406721 (2), 9174411 (1), 18289097 (1), 1559967 (1) (see all 7) |
| amide |
24.5 |
1 |
9154965 (1) |
| methionine |
16 |
2 |
15336565 (1) |
| tyrosine |
15.3 |
6 |
16998534 (3), 11594778 (2), 15613341 (1) |
| adp |
14.1 |
1 |
9575206 (1) |
Search CenterWatch for drugs/clinical trials and news about NMT1
|
Transcripts
for NMT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NMT1 gene: NM_021079.3 Unigene Cluster for NMT1: N-myristoyltransferase 1 Hs.532790 [show with all ESTs]Unigene Representative Sequence: NM_02107913 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592782 ENST00000588975 ENST00000543908 ENST00000585561 ENST00000590114
ENST00000592654 ENST00000588455 ENST00000590310 ENST00000587014 ENST00000591931
ENST00000587120 ENST00000587670 ENST00000258960(uc010dac.1 uc002ihz.3 uc010dad.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NMT1 (NM_001379) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NMT1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMT1 |
Additional cDNA sequence: AF020500.1 AF043324.1 AK291936.1 AK303517.1 BC006538.2 BC006569.2 BC007258.2 BC008312.2 BC008579.1 BC109226.1 M86707.1 U79285.1 Y17208.1 Y17209.1 24/26 DOTS entries (see all 26): DT.453507 DT.100825424 DT.100716545 DT.100825427 DT.120953431 DT.406748 DT.86841140 DT.120953542 DT.120953473 DT.95072967 DT.95072992 DT.100825416 DT.120953422 DT.92450584 DT.95072972 DT.100825417 DT.100825418 DT.100825428 DT.120953497 DT.120953553 DT.40121631 DT.87017268 DT.95256377 DT.97829493 24/538 AceView cDNA sequences (see all 538): BM680605 BX281359 AA687510 R94875 BM148180 BM719795 AU280476 BU154964 AF043324 BQ130620 U79285 AI347632 BU632609 BP364503 AI586983 CD690102 BU634081 BQ009031 BC006538 D54523 CR626529 CK818838 CB160335 BF448762
GeneLoc Exon Structure
|
Expression
for NMT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NMT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGCCGTGAT
About this image
See NMT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NMT1
SOURCE GeneReport for Unigene cluster: Hs.532790
UniProtKB/Swiss-Prot: NMT1_HUMAN, P30419Tissue specificity: Heart, gut, kidney, liver and placenta
SABiosciences Custom PCR Arrays for NMT1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NMT1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NMT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NMT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NMT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMT1 |
Orthologs
for NMT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NMT1 gene from 9/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NMT11 |
N-myristoyltransferase 1 |
82.15(n)
90.3(a) |
|
419966 XM_418088.3 XP_418088.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NMT16 |
-- |
89(a) |
1 ↔ 1 |
6(64772650-64791101) |
African clawed frog
(Xenopus laevis) |
Amphibia |
nmt1-prov2 |
N-myristoyltransferase 1 |
79.62(n) |
|
BC041300.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc15d012 |
Danio rerio cDNA clone IMAGE2601337, partial cds |
79.4(n) |
|
BC056805.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Nmt1 , 3 |
N-terminal protein myristoylation
glycyl-peptide more3
N-myristoyl transferase1 |
65(a)3
63.38(n)1
65.66(a)1 |
|
66B103
389091 NM_079245.21 NP_523969.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
T17E9.2a3 |
-- |
57(a)
(best of 2) |
|
III(6186548-6188081) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
NMT1(YLR195C)4
NMT11 |
N-myristoyl transferase, catalyzes the cotranslational, more4
Nmt1p1 |
49.03(n)1
45.09(a)1 |
|
12(543304-541937)4
8508921, 4 NP_013296.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NMT11 |
glycylpeptide N-tetradecanoyltransferase 1 |
60.19(n)
57.25(a) |
|
835805 NM_125084.2 NP_568846.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.151432 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
75.59(n) |
|
AK101457.1 |
ENSEMBL Gene Tree for NMT1 (if available)
TreeFam Gene Tree for NMT1 (if available) |
Paralogs
for NMT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NMT1 gene
- NMT22
2 SIMAP similar genes for NMT1 using alignment to 6 protein entries: NMT1_HUMAN (see all proteins):NMT NMT2
NMT1 for paralogs About GeneDecksing
|
Genomic Variants
for NMT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NMT1 (43128978 - 43186384 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NMT1
1 CNV: 34646 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMT1 |
|
Disorders
/ Diseases
for NMT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NMT1 for disorders About GeneDecksing
OMIM gene information: 160993
OMIM disorders: --
20  diseases for NMT1: About MalaCardslambert-eaton myasthenic syndrome patent foramen ovale myasthenic syndrome oral squamous cell carcinoma
squamous cell carcinoma gallbladder carcinoma impotence hepatitis b
gallbladder cancer colon cancer thymoma ischemia
carcinoma hepatitis immunodeficiency adenocarcinoma
melanoma malaria leukemia neuronitis
10/13 Novoseek disease relationships for NMT1 gene (see all 13) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gallbladder carcinoma |
64.5 |
12 |
10813869 (4), 16846646 (1), 12239600 (1), 15756927 (1) (see all 5) |
| colon cancer |
49.7 |
10 |
18021392 (4), 10718634 (1), 15156568 (1), 16600465 (1) (see all 6) |
| epithelial tumor |
46.1 |
9 |
12239600 (1), 15756927 (1), 14633729 (1), 10891381 (1) |
| colorectal tumors |
32.2 |
2 |
12239600 (1), 9281363 (1) |
| immunodeficiency |
23.3 |
5 |
15613341 (1), 1559967 (1), 18089753 (1), 9191015 (1) (see all 5) |
| colorectal cancer |
10.5 |
3 |
18021392 (1), 16846646 (1) |
| adenocarcinoma |
6.21 |
10 |
9281363 (5), 17390089 (1), 16530191 (1), 10891381 (1) |
| brain tumors |
4.88 |
6 |
15756927 (2), 16846646 (1) |
| hepatitis b |
3.34 |
2 |
9191015 (1) |
| cancer |
2.19 |
12 |
16846646 (2), 18021392 (1), 12239600 (1), 16600465 (1) (see all 8) |
Human Genome Epidemiology (HuGE) Navigator: NMT1 (2 documents)
Export disorders for NMT1 gene to outside databases
|
Publications
for NMT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NMT1 gene, integrated from 9 sources (see all 147):
(articles sorted by number of sources associating them with NMT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae. (PubMed id 1570339)1, 2, 3, 9 Duronio R.J.... Gordon J.I. (1992)
- A second mammalian N-myristoyltransferase. (PubMed id 9506952)1, 2, 9 Giang D.K. and Cravatt B.F. (1998)
- Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction. (PubMed id 9353336)1, 2, 9 Glover C.J.... Felsted R.L. (1997)
- Characterization of human and rat brain myristoyl-CoA:protein N- myristoyltransferase: evidence for an alternative splice variant of the enzyme. (PubMed id 9677304)1, 2, 9 Mcilhinney R.A.J....Soloviev M. (1998)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef. (PubMed id 18089753)1, 9 Seaton K.E. and Smith C.D. (2008)
- N-myristoyltransferase: a potential novel diagnostic marker for colon cancer. (PubMed id 18021392)1, 9 Shrivastav A....Sharma R.K. (2007)
- Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. (PubMed id 16123142)1, 9 Ducker C.E....Smith C.D. (2005)
- Phosphorylation of human N-myristoyltransferase by N-myristoylated SRC family tyrosine kinase members. (PubMed id 11594778)1, 9 Rajala R.V....Sharma R.K. (2001)
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External Searches for NMT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing NMT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing NMT1 gene
(According to HUGE)
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Specialized Databases showing NMT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for NMT1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for NMT1 gene:
Search GeneIP for patents involving NMT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NMT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NMT1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NMT1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NMT1 | | | OriGene Protein Over-expression Lysate for NMT1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NMT1 | | OriGene 3'-UTR Clone for NMT1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMT1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NMT1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NMT1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NMT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NMT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NMT1 |
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 | | | NMT1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMT1 |
|  |  |  | | | | ThermoFisher Antibodies for NMT1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMT1 |
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