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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NMRK1 Gene

protein-coding GIFtS: 51
GCID: GC09M077675

nicotinamide riboside kinase 1

(Previous name: chromosome 9 open reading frame 95 )
(Previous symbol: C9orf95)

Explore 3 diseases affiliated with
NMRK1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Nicotinamide Riboside Kinase 1¹ ²		Ribosylnicotinic Acid Kinase 1² ³
C9orf95¹ ² ³		NRK 1² ³
NRK1¹ ² ³		RNK 1² ³
BA235O14.2¹		FLJ20559¹
Nicotinic Acid Riboside Kinase 1² ³		Chromosome 9 Open Reading Frame 95¹
NmR-K 1² ³		EC 2.7.1.173³
Ribosylnicotinamide Kinase 1² ³		EC 2.7.1.22³

External Ids:	HGNC: 26057¹	Entrez Gene: 54981²	Ensembl: ENSG00000106733⁷	OMIM: 608704⁵	UniProtKB: Q9NWW6³

ORGUL members:
	NONCODE:n406461

Export aliases for NMRK1 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NMRK1:

Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases

and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known

as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize

NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004

(PubMed 15137942)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6

Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form

nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the

antitumor drugs tiazofurin and 3-deazaguanosine

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008470.19

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for NMRK1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for NMRK1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMRK1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21.13 Ensembl cytogenetic band: 9q21.13 HGNC cytogenetic band: 9q21.31

NMRK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NMRK1 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M077675: view genomic region (about GC identifiers)

Start:	77,675,489 bp from pter	End:	77,703,133 bp from pter
Size:	27,645 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6 (See protein sequence)

Recommended Name: Nicotinamide riboside kinase 1

Size: 199 amino acids; 23193 Da

Subunit: Monomer

6/7 PDB 3D structures from and Proteopedia for NMRK1 (see all 7):

2P0E (3D)

2QG6 (3D)

2QL6 (3D)

2QSY (3D)

2QSZ (3D)

2QT0 (3D)

Secondary accessions: Q5W124 Q8N430

Alternative splicing: 2 isoforms: Q9NWW6-1 Q9NWW6-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NMRK1: NX_Q9NWW6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NWW6

NMRK1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001121075.1 NP_060351.1

ENSEMBL proteins:

ENSP00000366007 ENSP00000354387 ENSP00000366004 ENSP00000435736

Human Recombinant Protein Products:

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	Novus Biologicals NMRK1 Proteins Novus Biologicals NMRK1 Lysates
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	Uscn Proteins for NMRK1

NMRK1 Antibody Products:

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	Uscn ELISAs and CLIAs for NMRK1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NMRK1 for domains About GeneDecksing

1 InterPro domain/family:

IPR000764 Uridine_kinase

Graphical View of Domain Structure for InterPro Entry Q9NWW6

ProtoNet protein and cluster: Q9NWW6

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6

Similarity: Belongs to the uridine kinase family. NRK subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6

Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form

nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the

antitumor drugs tiazofurin and 3-deazaguanosine

Catalytic activity: ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide

Catalytic activity: ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide

Biophysicochemical properties: Kinetic parameters: KM=0.088 mM for nicotinamide riboside (with ATP as cosubstrate);

KM=0.068 mM for nicotinamide riboside (with GTP as cosubstrate); KM=0.27 mM for tiazofurin (with ATP as cosubstrate);

KM=0.051 mM for nicotinic acid riboside (with ATP as cosubstrate); KM=17 mM for uridine (with ATP as cosubstrate); pH

dependence: Optimum pH is 6.5-9;

Enzyme Numbers (IUBMB): EC 2.7.1.22¹ EC 2.7.1.173¹

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NMRK1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NMRK1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NMRK1
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NMRK1 (see all 4) OriGene shRNA RFP: NMRK1 OriGene siRNA: NMRK1
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for NMRK1

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMRK1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMRK1 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Search LifeMap BioReagents cell lines for NMRK1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMRK1

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004849	uridine kinase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016301	kinase activity	--	--
GO:0016773	phosphotransferase activity, alcohol group as acceptor	--	--
GO:0046872	metal ion binding	IEA	--

NMRK1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

NAD metabolism

	NAD metabolism	1.00			Nicotinate and nicotinamide metabolism	0.43
	NAD metabolism	1.00

Nicotinate metabolism

NAD salvage pathway III

0.30

NAD salvage pathway II

0.18

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for NMRK1

NAD metabolism

1 GeneGo (Thomson Reuters) Pathway for NMRK1

NAD metabolism

2 BioSystems Pathways for NMRK1

	NAD salvage pathway III
	NAD salvage pathway II

1 Kegg Pathway (Kegg details for NMRK1):

Nicotinate and nicotinamide metabolism

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6

Pathway: Cofactor biosynthesis; NAD(+) biosynthesis

NMRK1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NMRK1

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

5/18 Interacting proteins for NMRK1 (Q9NWW6³ ENSP00000354387⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 18)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DPP8	Q6V1X1³	I2D: score=3
NMNAT1	ENSP00000366410⁴	STRING: ENSP00000366410
NMNAT3	ENSP00000340523⁴	STRING: ENSP00000340523
QPRT	ENSP00000378782⁴	STRING: ENSP00000378782
ENPP1	ENSP00000354238⁴	STRING: ENSP00000354238

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009435	NAD biosynthetic process	IEA	--

NMRK1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NMRK1
Search CenterWatch for drugs/clinical trials and news about NMRK1 / NRK1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NMRK1 gene (2 alternative transcripts):

NM_001127603.1 NM_017881.2

Unigene Cluster for NMRK1:

Nicotinamide riboside kinase 1

Hs.494186 [show with all ESTs]

Unigene Representative Sequence: AK097144

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000376811(uc004ajs.4) ENST00000361092(uc004ajr.4) ENST00000376808(uc004ajt.4)

ENST00000482537 ENST00000494066 ENST00000466137 ENST00000490321

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NMRK1 Browse OriGene MicroRNA Expression Plasmids
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMRK1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMRK1 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Additional cDNA sequence:

AK000566.1 AK023413.1 AK097144.1 AY611480.1 BC001366.2 BC026243.1 BC036804.1 NR_023352.1

17 DOTS entries:

DT.313829 DT.97844943 DT.100794515 DT.99967347 DT.100794516 DT.100794517 DT.121150198 DT.313830

DT.121150203 DT.121150213 DT.313831 DT.121150220 DT.97803701 DT.121150202 DT.121150242 DT.433355

DT.75151951

24/131 AceView cDNA sequences (see all 131):

CB268022 BF726171 AI561257 BM544620 NM_017881 CR611964 AU134537 BQ271148

AI332858 AI969714 CD367257 BM706234 AK000566 BF061939 BC026243 CB528872

BE502779 AA595246 BX118139 CB530060 AI250062 AA195103 AL555401 BC036804

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for NMRK1 (see all 11) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6a	·	6b	^	7a	·	7b	^	8	^	9a	·	9b	·	9c	^	10	^	11	^	12a	·	12b	^	13a	·	13b
SP1:									-		-				-		-		-		-														-						-
SP2:									-		-				-		-		-		-		-												-						-
SP3:									-		-				-		-		-		-		-												-		-				-
SP4:									-		-				-		-		-		-		-																		-
SP5:									-		-				-		-		-																-

ECgene alternative splicing isoforms for NMRK1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NMRK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAATGGACA

About this image

NMRK1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NMRK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NMRK1

SOURCE GeneReport for Unigene cluster: Hs.494186

SABiosciences Custom PCR Arrays for NMRK1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMRK1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for NMRK1 gene from 4/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CZH9orf95¹	chromosome Z open reading frame, human C9orf95	69.11(n) 63.87(a)		427257 XM_424839.2 XP_424839.2
lizard (Anolis carolinensis)	Reptilia	C9orf95⁶	--	75(a)	1 ↔ 1	2(46875781-46880877)
zebrafish (Danio rerio)	Actinopterygii	zgc:113113¹	zgc:113113	58.69(n) 52.13(a)		541321 NM_001013449.1 NP_001013467.1
fruit fly (Drosophila melanogaster)	Insecta	CG42456¹	CG42456	46.6(n) 35.92(a)		8674033 NM_168022.2 NP_728865.1

ENSEMBL Gene Tree for NMRK1 (if available)
TreeFam Gene Tree for NMRK1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NMRK1 gene

NMRK2²

2 SIMAP similar genes for NMRK1 using alignment to 3 protein entries: NRK1_HUMAN (see all proteins):

NMRK2 ITGB1BP3

NMRK1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144208451^1,2		--	77675632(+)	`CCACAA/TGATTG`	3	--	int¹		0	--	--	--	--
rs117268855^1,2	F,	--	77675700(+)	`CACGAG/CGGGGG`	3	--	int¹		1		NA	120
rs10525751^1,2	C,	--	77675777(+)	`CGCCA-/ACACACACACA CACACACACACACACACA`	3	--	int¹		0	--	--	--	--
rs72118558^1,2	C	--	77675777(+)	`CGCCA-/ACAC ACACA`	3	--	int¹		0	--	--	--	--
rs72266057^1,2	C	--	77675777(+)	`CGCCA-/ACA CACACACACA`	3	--	int¹		0	--	--	--	--
rs11144207^1,2	C,F,A,H,	--	77675778(+)	`GCCAAC/AACACA`	3	--	int¹ ese³		16		NS EA NA CSA	1984
rs68188075^1,2	C	--	77675779(+)	`CACAC-/ACAC TCAAC`	3	--	int¹		1		NA	2
rs146050445^1,2		--	77675851(+)	`GTAGCA/GAATTG`	3	--	int¹		0	--	--	--	--
rs182383914^1,2		--	77675930(+)	`GATGGC/TATGGA`	3	--	int¹		0	--	--	--	--
rs773156^1,2	C,F,A,H,	--	77675966(+)	`GATCAG/ATATGT`	3	--	int¹		10		EA NS NA WA CSA	311

HapMap Linkage Disequilibrium report for NMRK1 (77675489 - 77703133 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NMRK1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMRK1

DNA2.0 Custom Variant and Variant Library Synthesis for NMRK1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NMRK1 for disorders           About GeneDecksing

OMIM gene information: 608704    OMIM disorders: --

3 diseases for NMRK1:    About MalaCards

intrahepatic cholangiocarcinoma cholangiocarcinoma alcoholism

Export disorders for NMRK1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NMRK1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NMRK1)

Utopia: connect your pdf to the dynamic
world of online information

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. (PubMed id 15137942)^{1, 2, 3} Bieganowski P. and Brenner C. (2004)
Crystal structure of human nicotinamide riboside kinase. (PubMed id 17698003)^{1, 2} Khan J.A.... Tong L. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)^{1, 2} Humphray S.J.... Dunham I. (2004)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Nicotinamide riboside kinase structures reveal new pathways to NAD+. (PubMed id 17914902)² Tempel W.... Brenner C. (2007)
Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)¹ Wang A.G....Kim N.S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Purification and properties of a human nicotinamide ribonucleoside kinase. (PubMed id 8809081)² Sasiak K. and Saunders P.P. (1996)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54981	HGNC: 26057	AceView: C9orf95	Ensembl:ENSG00000106733	euGenes: HUgn54981
ECgene: NMRK1	Kegg: 54981	H-InvDB: NMRK1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NMRK1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NMRK1 gene
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Patent Information for NMRK1 gene:
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