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NMRK1 Gene

protein-coding   GIFtS: 49
GCID: GC09M077675

Nicotinamide Riboside Kinase 1

(Previous name: chromosome 9 open reading frame 95)
(Previous symbol: C9orf95)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nicotinamide Riboside Kinase 11 2     NRK 12 3
C9orf951 2 3     RNK 12 3
Nicotinic Acid Riboside Kinase 12 3     Chromosome 9 Open Reading Frame 951
NmR-K 12 3     bA235O14.22
Ribosylnicotinamide Kinase 12 3     EC 2.7.1.1733
Ribosylnicotinic Acid Kinase 12 3     EC 2.7.1.223
NRK12 3     

External Ids:    HGNC: 260571   Entrez Gene: 549812   Ensembl: ENSG000001067337   OMIM: 6087045   UniProtKB: Q9NWW63   

Export aliases for NMRK1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NMRK1 Gene:
Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for
oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide,
collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1,
function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor
(Bieganowski and Brenner, 2004 (PubMed 15137942)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NMRK1 Gene:
NMRK1 (nicotinamide riboside kinase 1) is a protein-coding gene. Diseases associated with NMRK1 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. GO annotations related to this gene include uridine kinase activity and ribosylnicotinamide kinase activity. An important paralog of this gene is NMRK2.

UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6
Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form
nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the
antitumor drugs tiazofurin and 3-deazaguanosine




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NMRK1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NMRK1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NMRK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21.13   Ensembl cytogenetic band:  9q21.13   HGNC cytogenetic band: 9q21.31

NMRK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NMRK1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M077675:  view genomic region     (about GC identifiers)

Start:
77,675,489 bp from pter      End:
77,703,133 bp from pter
Size:
27,645 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6 (See protein sequence)
Recommended Name: Nicotinamide riboside kinase 1  
Size: 199 amino acids; 23193 Da
Subunit: Monomer
Selected PDB 3D structures from and Proteopedia for NMRK1 (see all 7):
2P0E (3D)        2QG6 (3D)        2QL6 (3D)        2QSY (3D)        2QSZ (3D)        2QT0 (3D)    
Secondary accessions: Q5W124 Q8N430
Alternative splicing: 2 isoforms:  Q9NWW6-1   Q9NWW6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NMRK1: NX_Q9NWW6

Explore proteomics data for NMRK1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NMRK1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001121075.1  NP_060351.1  

    ENSEMBL proteins: 
     ENSP00000366007   ENSP00000354387   ENSP00000366004   ENSP00000435736  

    NMRK1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000764 Uridine_kinase
     IPR026681 NRK

    Graphical View of Domain Structure for InterPro Entry Q9NWW6

    ProtoNet protein and cluster: Q9NWW6

    UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6
    Similarity: Belongs to the uridine kinase family. NRK subfamily


    NMRK1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NRK1_HUMAN, Q9NWW6
    Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form
    nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the
    antitumor drugs tiazofurin and 3-deazaguanosine
    Catalytic activity: ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide
    Catalytic activity: ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide
    Biophysicochemical properties: Kinetic parameters: KM=0.088 mM for nicotinamide riboside (with ATP as
    cosubstrate); KM=0.068 mM for nicotinamide riboside (with GTP as cosubstrate); KM=0.27 mM for tiazofurin (with
    ATP as cosubstrate); KM=0.051 mM for nicotinic acid riboside (with ATP as cosubstrate); KM=17 mM for uridine
    (with ATP as cosubstrate); pH dependence: Optimum pH is 6.5-9;

         Enzyme Numbers (IUBMB): EC 2.7.1.221 EC 2.7.1.1731

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004849uridine kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0046872metal ion binding IEA--
    GO:0050262ribosylnicotinamide kinase activity IEA--
         
    NMRK1 for ontologies           About GeneDecksing


    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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      --

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NMRK1 About    
    See pathways by source

    SuperPathContained pathways About
    1Nicotinate and nicotinamide metabolism
    Nicotinate and nicotinamide metabolism0.43
    NAD metabolism0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NMRK1
        NAD metabolism


    1 Kegg Pathway  (Kegg details for NMRK1):
        Nicotinate and nicotinamide metabolism

    UniProtKB/Swiss-Prot: NRK1_HUMAN, Q9NWW6
    Pathway: Cofactor biosynthesis; NAD(+) biosynthesis


    NMRK1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NMRK1
    Interactions:

        Search GeneGlobe Interaction Network for NMRK1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NMRK1 (Q9NWW63 ENSP000003543874) via UniProtKB, MINT, STRING, and/or I2D (see all 37)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    DPP8Q6V1X13I2D: score=3 
    NMNAT1ENSP000003664104STRING: ENSP00000366410
    NMNAT2ENSP000002877134STRING: ENSP00000287713
    NMNAT3ENSP000003405234STRING: ENSP00000340523
    NUDT12ENSP000002307924STRING: ENSP00000230792
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009435NAD biosynthetic process IEA--
    GO:0019359nicotinamide nucleotide biosynthetic process ----

    NMRK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NMRK1 (NRK1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NMRK1 gene (2 alternative transcripts): 
    NM_001127603.1  NM_017881.2  

    Unigene Cluster for NMRK1:

    Nicotinamide riboside kinase 1
    Hs.494186  [show with all ESTs]
    Unigene Representative Sequence: AK097144
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376811(uc004ajs.4) ENST00000482537 ENST00000361092(uc004ajr.4)
    ENST00000376808(uc004ajt.4) ENST00000494066 ENST00000466137 ENST00000490321

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    Predesigned siRNA for gene silencing in human, mouse, rat NMRK1
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    Additional mRNA sequence: 

    AK000566.1 AK023413.1 AK097144.1 AY611480.1 BC001366.2 BC026243.1 BC036804.1 NR_023352.1 

    17 DOTS entries:

    DT.313829  DT.97844943  DT.100794515  DT.99967347  DT.100794516  DT.100794517  DT.121150198  DT.313830 
    DT.121150203  DT.121150213  DT.313831  DT.121150220  DT.97803701  DT.121150202  DT.121150242  DT.433355 
    DT.75151951 

    Selected AceView cDNA sequences (see all 131):

    AL555401 BE502779 AA195103 BQ271148 AI561257 AI969714 BM544620 AU134537 
    AA568203 AA554498 F11214 CR611964 BF061939 BC036804 BF726171 CB268022 
    AY611480 AI332858 CD519977 BM706234 AK000566 CD367257 AA595246 AI979008 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NMRK1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b
    SP1:                          -     -           -     -     -     -                                         -                 -                     
    SP2:                          -     -           -     -     -     -     -                                   -                 -                     
    SP3:                          -     -           -     -     -     -     -                                   -     -           -                     
    SP4:                          -     -           -     -     -     -     -                                                     -                     
    SP5:                          -     -           -     -     -                                               -                                       


    ECgene alternative splicing isoforms for NMRK1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NMRK1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAATGGACA
    NMRK1 Expression
    About this image

    NMRK1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NMRK1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.494186
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NMRK1 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nmrk11 , 5 cDNA sequence BC0164955
    nicotinamide riboside kinase 11
    83.42(n)1
    81.03(a)1
      19 (13.17 cM)5
    2259941  NM_145497.21  NP_663472.11 
     186319505 
    chicken
    (Gallus gallus)
    Aves CZH9ORF951 chromosome Z open reading frame, human C9orf95 68.68(n)
    63.32(a)
      427257  XM_004949169.1  XP_004949226.1 
    lizard
    (Anolis carolinensis)
    Reptilia NMRK16
    nicotinamide riboside kinase 1
    72(a)
    1 ↔ 1
    2(46875781-46880895)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nmrk11 nicotinamide riboside kinase 1 65.28(n)
    56.99(a)
      100125192  NM_001103077.1  NP_001096547.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nmrk11 nicotinamide riboside kinase 1 58.69(n)
    52.13(a)
      541321  NM_001013449.2  NP_001013467.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120161 CG12016 48.93(n)
    38.01(a)
      38411  NM_139548.4  NP_647805.1 


    ENSEMBL Gene Tree for NMRK1 (if available)
    TreeFam Gene Tree for NMRK1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NMRK1 gene
    NMRK22  
    2 SIMAP similar genes for NMRK1 using alignment to 3 protein entries:     NRK1_HUMAN (see all proteins):
    NMRK2    ITGB1BP3

    NMRK1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NMRK1 (see all 521)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1442084511,2
    --77675632(+) CCACAA/TGATTG 3 -- int10--------
    rs1172688551,2
    C,F--77675700(+) CACGAG/CGGGGG 3 -- int11Minor allele frequency- C:0.07NA 120
    rs111442071,2
    C,F,A,H--77675778(+) GCCAAC/AACACA 3 -- int1 ese316Minor allele frequency- A:0.08NS EA NA CSA 1984
    rs1460504451,2
    C--77675851(+) GTAGCA/GAATTG 3 -- int10--------
    rs1823839141,2
    --77675930(+) GATGGC/TATGGA 3 -- int10--------
    rs7731561,2
    C,F,A,H--77675966(+) GATCAG/ATATGT 3 -- int110Minor allele frequency- A:0.31EA NS NA WA CSA 311
    rs1408717551,2
    C--77675970(+) AATAT-/GTTTTT 3 -- int10--------
    rs7731571,2
    C,F,H--77675978(+) TTTTAA/TAATTA 3 -- int115Minor allele frequency- T:0.04NS EA NA WA CSA 534
    rs1398023431,2
    C--77675988(+) AAAGAC/TGGAAA 3 -- int10--------
    rs7731581,2
    C,F,H--77676046(+) TGTATG/TTATGT 3 -- int1 ese316Minor allele frequency- T:0.02NS EA NA WA 1738

    HapMap Linkage Disequilibrium report for NMRK1 (77675489 - 77703133 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NMRK1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NMRK1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608704    OMIM disorders: --

    3 diseases for NMRK1:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    malaria


    NMRK1 for disorders           About GeneDecksing


    Export disorders for NMRK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NMRK1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with NMRK1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. (PubMed id 15137942)1, 2, 3 Bieganowski P. and Brenner C. (Cell 2004)
    2. Crystal structure of human nicotinamide riboside kinase. (PubMed id 17698003)1, 2 Khan J.A.... Tong L. (Structure 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. Nicotinamide riboside kinase structures reveal new pathways to NAD+. (PubMed id 17914902)2 Tempel W.... Brenner C. (PLoS Biol. 2007)
    9. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54981 HGNC: 26057 AceView: C9orf95 Ensembl:ENSG00000106733 euGenes: HUgn54981
    ECgene: NMRK1 Kegg: 54981 H-InvDB: NMRK1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NMRK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NMRK1 gene:
    Search GeneIP for patents involving NMRK1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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