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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NMRAL1 Gene

protein-coding   GIFtS: 47
GCID: GC16M004452

NmrA-like family domain containing 1
  Search for NMRAL1
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NMRAL1    

Aliases
for NMRAL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
NmrA-Like Family Domain Containing 11 2
HSCARG1 2 3
SDR48A11 2
FLJ259181
NmrA-Like Family Domain-Containing Protein 12
Short Chain Dehydrogenase/Reductase Family 48A, Member 12

External Ids:    HGNC: 249871   Entrez Gene: 574072   Ensembl: ENSG000001534067   UniProtKB: Q9HBL83   

Export aliases for NMRAL1 gene to outside databases


Summaries
for NMRAL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NMRL1_HUMAN, Q9HBL8
Function: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in
intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds
argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its
activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH
concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule
of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer




Genomic Views
for NMRAL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NMRAL1 gene promoter:
         AhR   E2F-3a   E2F-4   E2F-5   E2F-2   CREB   E2F-1   E2F   RSRFC4   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NMRAL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NMRAL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMRAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

NMRAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NMRAL1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M004452:  view genomic region     (about GC identifiers)

Start:
 4,511,681 bp from pter      End:
 4,545,764 bp from pter
Size:
 34,084 bases      Orientation:
 minus strand

Proteins
for NMRAL1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NMRL1_HUMAN, Q9HBL8 (See protein sequence)
Recommended Name: NmrA-like family domain-containing protein 1  
Size: 299 amino acids; 33344 Da
Subunit: Homodimer. Interacts with ASS1. Interaction is enhanced by low NADPH/NADP(+) ratios, which results in
inhibition of ASS1 activity
Subcellular location: Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Under normal redox growth conditions
localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric
oxide and reduced NADPH/NADP(+) ratios
Miscellaneous: Reduced levels of NMRAL1 by RNAi increases nitric oxide production and reduces cell viability.
Overexpression of NMRAL1 increases cell viability
Caution: Lacks the conserved Tyr residue in the active site triad of Ser-Tyr-Lys necessary for dehydrogenase activity,
suggesting that it has no oxidoreductase activity
5 PDB 3D structures from and Proteopedia for NMRAL1:
2EXX (3D)        2WM3 (3D)        2WMD (3D)        3DXF (3D)        3E5M (3D)    

Explore the universe of human proteins at neXtProt for NMRAL1: NX_Q9HBL8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9HBL8

    • NMRAL1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065728.1  
    ENSEMBL proteins: 
     ENSP00000283429   ENSP00000458762   ENSP00000461763   ENSP00000459221   ENSP00000383962  
     ENSP00000460263   ENSP00000460837   ENSP00000460476   ENSP00000459926   ENSP00000459022  
     ENSP00000458425  

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    Novus Biologicals NMRAL1 Proteins
    Novus Biologicals NMRAL1 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for NMRAL1
    Uscn Proteins for NMRAL1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0048471perinuclear region of cytoplasm IEA--


    NMRAL1 for ontologies           About GeneDecksing



    NMRAL1 Antibody Products: 
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    Uscn Antibodies for NMRAL1
    ThermoFisher Antibodies for NMRAL1

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    Uscn ELISAs and CLIAs for NMRAL1

    Protein Domains /
    Families
    for NMRAL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NMRAL1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR016040 NAD(P)-bd_dom
     IPR008030 NmrA

    Graphical View of Domain Structure for InterPro Entry Q9HBL8

    ProtoNet protein and cluster: Q9HBL8

    UniProtKB/Swiss-Prot: NMRL1_HUMAN, Q9HBL8
    Similarity: Belongs to the NmrA-type oxidoreductase family


    Function
    for NMRAL1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NMRL1_HUMAN, Q9HBL8
    Function: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in
    intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds
    argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its
    activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH
    concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule
    of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer
    Induction: By nitric oxide, cGMP and proinflammatory cytokines

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: NMRAL1
    OriGene siRNA: NMRAL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NMRAL1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NMRAL1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMRAL1 (see all 2)
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    Cell Line
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    Search LifeMap BioReagents cell lines for NMRAL1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMRAL1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--


    NMRAL1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NMRAL1:
     Decreased TP53 protein express 


    Pathways & Interactions
    for NMRAL1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NMRAL1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for NMRAL1 (ENSP000002834294) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    FOXJ1ENSP000003238804STRING: ENSP00000323880
    About this table

    Drugs & Compounds
    for NMRAL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NMRAL1

    1 DrugBank Compound for NMRAL1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about NMRAL1 / NMRL1 

    Transcripts
    for NMRAL1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NMRAL1 gene: 
    NM_020677.3  

    Unigene Cluster for NMRAL1:

    NmrA-like family domain containing 1
    Hs.288969  [show with all ESTs]
    Unigene Representative Sequence: BM458171
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283429(uc002cwo.3) ENST00000574733(uc002cwn.3) ENST00000571448
    ENST00000572232 ENST00000404295(uc002cwm.3) ENST00000574425 ENST00000572110
    ENST00000573533 ENST00000576176 ENST00000571291 ENST00000572391 ENST00000573520
    ENST00000573571 ENST00000575002 ENST00000575557 ENST00000576935 ENST00000575995
    ENST00000572559

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NMRAL1
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NMRAL1 (see all 4)
    OriGene shRNA RFP: NMRAL1
    OriGene siRNA: NMRAL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NMRAL1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMRAL1
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    GenScript: all cDNA clones in your preferred vector: NMRAL1 (NM_020677)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NMRAL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NMRAL1

    Additional cDNA sequence: 

    AF225419.1 AK098784.1 BC002927.2 BC007364.2 

    16 DOTS entries:

    DT.75105422  DT.100677718  DT.100816267  DT.95312856  DT.446751  DT.100816264  DT.100737452  DT.120676666 
    DT.95215789  DT.120676645  DT.100702406  DT.100816265  DT.95215803  DT.100036355  DT.40125288  DT.95073778 

    24/217 AceView cDNA sequences (see all 217):

    CR608452 CR622057 BU944032 BM978613 BX115709 CB529496 AI206495 BE886955 
    CD676285 AI908114 AI783775 AW006467 CA488996 CB850503 BQ221699 BC002927 
    CA424114 BM912560 BG222843 CR606906 CB053984 BI793072 BC007364 AK098784 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for NMRAL1 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ·
    SP1:                                      -     -     -     -           -     -     -                 -                       -                 -               
    SP2:                                                  -     -           -     -     -                 -                       -                 -               
    SP3:                                                        -           -     -     -                 -                       -                 -               
    SP4:                                                        -                 -     -                 -                                                         
    SP5:                                                                                                                          -                                 

    ExUns: 12c
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for NMRAL1

    Expression
    for NMRAL1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NMRAL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCCGTTTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NMRAL1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyMetanephrosKidney
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NMRAL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NMRAL1

    SOURCE GeneReport for Unigene cluster: Hs.288969
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    In Situ
    Assay Products:     
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    Orthologs
    for NMRAL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for NMRAL1 gene from 3/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nmral11 , 5 NmrA-like family domain containing 11, 5 82.09(n)1
    85.47(a)1    		   16 (2.46 cM)5
    678241  NM_026393.11  NP_080669.11 
     47100595 
    chicken
    (Gallus gallus)    		 Aves NMRAL11 NmrA-like family domain containing 1 70.72(n)
    64.86(a)    		   416672  NM_001030645.1  NP_001025816.1 
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.99982 Xenopus laevis transcribed sequence with weak similarity to protein refNP_065728.1 (H.sapiens) HSCARG protein [Homo sapiens] less 74.38(n)    CB559958.1 


    ENSEMBL Gene Tree for NMRAL1 (if available)
    TreeFam Gene Tree for NMRAL1 (if available) 

    Paralogs
    for NMRAL1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NMRAL1 gene
    1 SIMAP similar gene for NMRAL1 using alignment to 8 protein entries:     NMRL1_HUMAN (see all proteins):
    PLA2G15

    NMRAL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NMRAL1
    PGOHUM00000262438


    Genomic Variants
    for NMRAL1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/262 NCBI SNPs in NMRAL1 are shown (see all 262)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1913318971,2
    		--4511247(+) ATGAAA/CGGGGT 1 -- int10--------
    rs1117492181,2
    		C,--4511332(+) GGGAAC/TAGAGG 1 -- int12Minor allele frequency- T:0.02NA 122
    rs745047001,2
    		F,--4511357(+) TGTTCT/CGCTAG 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1424674471,2
    		--4511405(+) AAACAC/TGTTTA 1 -- int10--------
    rs711396331,2
    		C--4511558(+) CCCCC-/CGCTCC 1 -- int12Minor allele frequency- C:0.25NA 4
    rs1148881341,2
    		F,--4511565(+) CCCCCC/GCCCCG 1 -- int11Minor allele frequency- G:0.06WA 118
    rs1828217521,2
    		--4511601(+) AGCCCC/TGGACC 1 -- int10--------
    rs1482062521,2
    		--4511614(+) CCCCAA/GCCACT 1 -- int10--------
    rs2005346341,2
    		--4511743(+) TCTGGA/TGCCCC 1 -- ut310--------
    rs71914581,2
    		C,F,A,H,--4511752(+) CCCGAT/CCCCCA 1 -- ut3115Minor allele frequency- C:0.12NS EA WA NA EU 2801

    HapMap Linkage Disequilibrium report for NMRAL1 (4511681 - 4545764 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for NMRAL1
         1 CNV: 72438

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMRAL1
    DNA2.0 Custom Variant and Variant Library Synthesis for NMRAL1

    Disorders / Diseases
    for NMRAL1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for NMRAL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NMRAL1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with NMRAL1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. NADPH is an allosteric regulator of HSCARG. (PubMed id 19254724)1, 2 Dai X....Zheng X. (2009)
    2. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
    3. An NADPH sensor protein (HSCARG) down-regulates nitric oxide synthesis by association with argininosuccinate synthetase and is essential for epithelial cell viability. (PubMed id 18263583)1, 2 Zhao Y.... Zheng X. (2008)
    4. Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. (PubMed id 17496144)1, 2 Zheng X....Luo M. (2007)
    5. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    8. A CRM1-dependent nuclear export signal controls nucleo cytoplasmic translocation of HSCARG, which regulates NF-kB activity. (PubMed id 22348310)1 Zhang M....Zheng X. (2012)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    External Searches for NMRAL1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing NMRAL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57407 HGNC: 24987 AceView: HSCARG Ensembl:ENSG00000153406 euGenes: HUgn57407
    ECgene: NMRAL1 H-InvDB: NMRAL1

    Other Databases showing NMRAL1 gene

    (According to HUGE)
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    		   --

    Specialized Databases showing NMRAL1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NMRAL1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NMRAL1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NMRAL1 gene:
    Search GeneIP for patents involving NMRAL1

    GeneCards and IP:
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