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NME9 Gene

protein-coding   GIFtS: 42
GCID: GC03M137981

NME/NM23 Family Member 9

(Previous names: thioredoxin domain containing 6, NME gene family member...)
(Previous symbol: TXNDC6)
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Aliases
for NME9 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NME/NM23 Family Member 91 2     TXL22 3
TXNDC61 2 3     NM23-H92
NME Family Member 91 2     TXL-22
NME Gene Family Member 91 2     Thioredoxin Domain-Containing Protein 62
Thioredoxin Domain Containing 61 2     Thioredoxin-Like 22
Thioredoxin-Like Protein 22 3     Txl-23

External Ids:    HGNC: 213431   Entrez Gene: 3477362   Ensembl: ENSG000001813227   UniProtKB: Q86XW93   

Export aliases for NME9 gene to outside databases


Summaries
for NME9 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NME9 Gene:
NME9 (NME/NM23 family member 9) is a protein-coding gene. Diseases associated with NME9 include pneumonia, and alzheimer's disease. GO annotations related to this gene include nucleoside diphosphate kinase activity. An important paralog of this gene is NME2.

UniProtKB/Swiss-Prot: TXND6_HUMAN, Q86XW9
Function: May be a regulator of microtubule physiology




Genomic Views
for NME9 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NME9
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NME9 promoter sequence
   Search Chromatin IP Primers for NME9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NME9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.3   Ensembl cytogenetic band:  3q22.3   HGNC cytogenetic band: 3q22.3

NME9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME9 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M137981:  view genomic region     (about GC identifiers)

Start:
 137,980,279 bp from pter      End:
 138,048,728 bp from pter
Size:
 68,450 bases      Orientation:
 minus strand

Proteins
for NME9 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TXND6_HUMAN, Q86XW9 (See protein sequence)
Recommended Name: Thioredoxin domain-containing protein 6  
Size: 330 amino acids; 36856 Da
Subunit: Monomer and homodimer
Miscellaneous: Shows no detectable enzyme activity
Secondary accessions: Q7Z4A8 Q8N1V7
Alternative splicing: 3 isoforms:  Q86XW9-1   Q86XW9-2   Q86XW9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NME9: NX_Q86XW9

Explore proteomics data for NME9 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See NME9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_835231.1  
    ENSEMBL proteins: 
     ENSP00000372667   ENSP00000419355   ENSP00000419882   ENSP00000335444   ENSP00000420435  
     ENSP00000419147   ENSP00000420668   ENSP00000420258   ENSP00000341084   ENSP00000321929  
     ENSP00000440143  

    NME9 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for NME9
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    Novus Biologicals NME9 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    NME9 Antibody Products:

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    Novus Biologicals NME9 Antibodies
    Abcam antibodies for NME9
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    ThermoFisher Antibody for NME9
    LSBio Antibodies in human, mouse, rat for NME9

    NME9 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NME9
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.

    Domains /
    Families
    for NME9 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    TryGeneCards Plus    		 4 InterPro protein domains:
     IPR001564 Nucleoside_diP_kinase
     IPR012336 Thioredoxin-like_fold
     IPR013766 Thioredoxin_domain
     IPR017937 Thioredoxin_CS

    Graphical View of Domain Structure for InterPro Entry Q86XW9

    ProtoNet protein and cluster: Q86XW9

    3 Blocks protein domains:
    IPB000408 Regulator of chromosome condensation
    IPB001564 Nucleoside diphosphate kinase
    IPB006662 Thioredoxin type domain


    UniProtKB/Swiss-Prot: TXND6_HUMAN, Q86XW9
    Similarity: Belongs to the NDK family
    Similarity: Contains 1 thioredoxin domain


    NME9 for domains           About GeneDecksing


    Function
    for NME9 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TXND6_HUMAN, Q86XW9
    Function: May be a regulator of microtubule physiology

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004550nucleoside diphosphate kinase activity IEA--
    GO:0005524ATP binding IEA--
         
    NME9 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NME9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NME9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NME9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NME9

    miRNA
    Products:            		Block miRNA regulation of human, mouse, rat NME9 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NME9
    SwitchGear 3'UTR luciferase reporter plasmid: NME9 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for NME9
    Predesigned siRNA for gene silencing in human, mouse, rat NME9

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NME9

    Clone
    Products:             		 OriGene clones in human, mouse for NME9 (see all 6)
    OriGene ORF clones in mouse, rat for NME9
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    GenScript Custom all cDNA clones Services for NME9
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NME9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NME9

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for NME9
    Browse ESI BIO Cell Lines and PureStem Progenitors for NME9 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NME9


    Localization
    for NME9 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TXND6_HUMAN, Q86XW9: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with
    microtubules. Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette (By
    similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--

    NME9 for ontologies           About GeneDecksing


    Pathways & Interactions
    for NME9 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NME9
    Interactions:

        Search GeneGlobe Interaction Network for NME9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for NME9 (ENSP000003219294) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUMO4ENSP000003186354STRING: ENSP00000318635
    GSRENSP000002211304STRING: ENSP00000221130
    MSRAENSP000003139214STRING: ENSP00000313921
    NSFENSP000003812934STRING: ENSP00000381293
    PRDX5ENSP000002654624STRING: ENSP00000265462
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    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006165nucleoside diphosphate phosphorylation ----
    GO:0006183GTP biosynthetic process IEA--
    GO:0006228UTP biosynthetic process IEA--
    GO:0006241CTP biosynthetic process IEA--
    GO:0045454cell redox homeostasis IEA--

    NME9 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NME9 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NME9 (TXND6)



    Transcripts
    for NME9 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NME9 gene: 
    NM_178130.2  

    Unigene Cluster for NME9:

    NME/NM23 family member 9
    Hs.660992  [show with all ESTs]
    Unigene Representative Sequence: NM_178130
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000383180(uc003ese.1) ENST00000492993 ENST00000484930 ENST00000333911(uc003esg.3)
    ENST00000474690 ENST00000478220 ENST00000475751 ENST00000488716 ENST00000460099
    ENST00000341790 ENST00000317876(uc003esd.1 uc010huf.1) ENST00000536478

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat NME9 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NME9
    SwitchGear 3'UTR luciferase reporter plasmid: NME9 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for NME9
    Predesigned siRNA for gene silencing in human, mouse, rat NME9
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NME9
    Primer
    Products:            		OriGene qSTAR qPCR primer pairs in human, mouse for NME9
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NME9
      QuantiTect SYBR Green Assays in human, mouse, rat NME9
      QuantiFast Probe-based Assays in human, mouse, rat NME9

    Additional mRNA sequence: 

    AF196568.1 AK094830.1 AY336746.1 BC107054.2 

    6 DOTS entries:

    DT.75119193  DT.40113384  DT.65286059  DT.91703436  DT.91998524  DT.92415449 

    15 AceView cDNA sequences:

    NM_178130 CA868240 AK094830 AI611656 AF196568 BF736559 CA867993 BG570189 
    BU607430 AY336746 CA312568 BE673422 BF850566 CD699916 AW869049 

    GeneLoc Exon Structure


    Expression
    for NME9 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NME9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTGCTGT
    NME9 Expression
    About this image

    NME9 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    NME9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.660992

    UniProtKB/Swiss-Prot: TXND6_HUMAN, Q86XW9
    Tissue specificity: Detected at very low levels in testis, lung and brain

        Custom PCR Arrays for NME9
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NME9

    Orthologs
    for NME9 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NME9 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nme91 , 5 thioredoxin domain containing 65
    NME/NM23 family member 91    		 80.79(n)1
    79.39(a)1    		   9 (51.72 cM)5
    6235341  NM_001165957.11  NP_001159429.11 
     994562435 
    zebrafish
    (Danio rerio)    		 Actinopterygii nme86
    		 NME/NM23 family member 8
    		 22(a)
    		 1 ↔ 1
    		 9(54049364-54120095) ENSDARG00000076395
    fruit fly
    (Drosophila melanogaster)    		 Insecta nmdyn-D66
    		 nmdyn-D6
    		 17(a)
    		 1 → many
    		 X(14477710-14478649)


    ENSEMBL Gene Tree for NME9 (if available)
    TreeFam Gene Tree for NME9 (if available)

    Paralogs
    for NME9 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NME9 gene
    NME22  NME12  NME32  NME82  NME42  NME72  NME1-NME22  NME62  
    NME52  
    2 SIMAP similar genes for NME9 using alignment to 5 protein entries:     TXND6_HUMAN (see all proteins):
    TXNDC6    NME8

    NME9 for paralogs           About GeneDecksing



    Genomic Variants
    for NME9 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NME9 (see all 557)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1867409651,2
    		C--138017732(+) GGAGGA/GTGATG 1 -- int10--------
    rs1146839991,2
    		C,F--138017799(+) TAAGGC/TGAAGA 1 -- int11Minor allele frequency- T:0.02WA 118
    rs778442781,2
    		C,F--138017919(+) GGCTGA/CCAGAA 1 -- int11Minor allele frequency- C:0.07WA 118
    rs1386847111,2
    		--138018217(+) AGCCCA/GGCCTG 1 -- int10--------
    rs64398001,2
    		C,F,H--138018341(+) CGCCAA/GTGAGT 1 -- int124Minor allele frequency- G:0.06NA NS EA WA CSA 1786
    rs1416040161,2
    		--138018399(+) CCTTAC/TACCCC 1 -- int10--------
    rs1390866441,2
    		--138018493(+) AGTAAC/TGGGAG 1 -- int10--------
    rs1416558621,2
    		C--138018574(+) CTGCCA/CAGCTA 1 -- int10--------
    rs779951881,2
    		C--138018607(+) AACACC/TCCCCG 1 -- int10--------
    rs1505111701,2
    		--138018646(+) TTCCCC/TTCTCT 1 -- int10--------

    HapMap Linkage Disequilibrium report for NME9 (137980279 - 138048728 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NME9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv4030CNV Insertion18451855
    nsv528349CNV Loss19592680
    nsv822263CNV Loss20364138
    nsv822264CNV Loss20364138
    nsv877537CNV Gain21882294
    nsv428422CNV Gain+Loss18775914

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NME9
    DNA2.0 Custom Variant and Variant Library Synthesis for NME9

    Disorders / Diseases
    for NME9 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for NME9:    
    About MalaCards
    pneumonia    alzheimer's disease    colorectal cancer


    NME9 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for NME9 gene to outside databases

    Publications
    for NME9 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NME9 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NME9)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of human thioredoxin-like 2. A novel microtubule- binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme. (PubMed id 12569107)1, 2, 3, 9 Sadek C.M....Miranda-Vizuete A. (J. Biol. Chem. 2003)
    2. Nme protein family evolutionary history, a vertebrate perspective. (PubMed id 19852809)1, 3 Desvignes T....Bobe J. (BMC Evol. Biol. 2009)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Thioredoxin-like protein 2 is overexpressed in colon cancer and promotes cancer cell metastasis by interaction with ran. (PubMed id 23311631)1 Lu Y....Fan D. (amp 2013)
    5. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PubMed id 21116278)1 Furney S.J.... . (Mol. Psychiatry 2011)
    6. Proteomic analysis in lung tissue of smokers and COPD patients. (PubMed id 18753468)1 Lee E.J....Uhm C.S. (Chest 2009)
    7. Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. (PubMed id 16236267)1 Guo D.... Wang C.-Y. (Biochem. Biophys. Res. Commun. 2005)
    8. The mammalian testis-specific thioredoxin system. (PubMed id 14713334)1 Miranda-Vizuete A....Oko R. (amp 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Identification and distribution of thioredoxin-like 2 as the antigen for the monoclonal antibody MC3 specific to colorectal cancer. (PubMed id 18528843)9 Lu Y....Fan D. (Proteomics 2008)

    External Searches for NME9 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NME9 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 347736 HGNC: 21343 AceView: TXNDC6 Ensembl:ENSG00000181322 euGenes: HUgn347736
    ECgene: NME9 H-InvDB: NME9

    Other Databases showing NME9 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing NME9 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NME9 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NME9 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for NME9 gene:
    Search GeneIP for patents involving NME9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for NME9 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     EMD Millipore genomic analysis products

      
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NME9
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NME9
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