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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NME7 Gene

protein-coding   GIFtS: 60
GCID: GC01M169101

NME/NM23 family member 7

(Previous names: non-metastatic cells 7, protein expressed in (nucleoside-diphosphate...)
 Explore 8 diseases affiliated with
NME7 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NME7    

Aliases
for NME7 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
NME/NM23 Family Member 71 2     MN23H72 5
Non-Metastatic Cells 7, Protein Expressed In (Nucleoside-Diphosphate Kinase)1 2     FLJ371941
NDK 72 3     NM23-H71
NDP Kinase 72 3     Nucleoside Diphosphate Kinase 72
Nm23-H71     Nucleoside-Diphosphate Kinase 72
EC 2.7.4.63 8     

External Ids:    HGNC: 204611   Entrez Gene: 299222   Ensembl: ENSG000001431567   OMIM: 6134655   UniProtKB: Q9Y5B83   

Export aliases for NME7 gene to outside databases

Previous GC identifers: GC01P166788 GC01M164752 GC01M165797 GC01M166289 GC01M165833 GC01M167368 GC01M140347


Summaries
for NME7 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NDK7_HUMAN, Q9Y5B8
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is
transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate




Genomic Views
for NME7 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NME7 gene promoter:
         STAT1   p53   Nkx2-2   STAT1beta   CUTL1   STAT1alpha   Egr-2   COMP1   En-1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NME7 promoter sequence
   Search SABiosciences Chromatin IP Primers for NME7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NME7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24   Ensembl cytogenetic band:  1q24.2   HGNC cytogenetic band: 1q24.2

NME7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME7 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M169101:  view genomic region     (about GC identifiers)

Start:
 169,101,769 bp from pter      End:
 169,337,205 bp from pter
Size:
 235,437 bases      Orientation:
 minus strand

Proteins
for NME7 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NDK7_HUMAN, Q9Y5B8 (See protein sequence)
Recommended Name: Nucleoside diphosphate kinase 7  
Size: 376 amino acids; 42492 Da
Cofactor: Magnesium (By similarity)
Secondary accessions: A8K3T6 A8MY09 B3KSW9 Q5TGZ4
Alternative splicing: 2 isoforms:  Q9Y5B8-1   Q9Y5B8-2   

Explore the universe of human proteins at neXtProt for NME7: NX_Q9Y5B8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y5B8

    • 3 DME Specific Peptides for NME7 (Q9Y5B8)
     NELIQFIT  DYGDQYTARQLGS  AAREMELFFPSSG 

    NME7 Protein expression data from MOPED and PaxDb:    About this image 
    NME7 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_037462.1  NP_932076.1  

    ENSEMBL proteins: 
     ENSP00000433341   ENSP00000356785   ENSP00000431467   ENSP00000432753  

    Human Recombinant Protein Products for NME7: 
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    Novus Biologicals NME7 Proteins
    Novus Biologicals NME7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NME7

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005813centrosome IDA--

    NME7 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NME7

    Protein Domains /
    Families
    for NME7 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NME7 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001564 Nucleoside_diP_kinase
     IPR006602 Uncharacterised_DM10
     IPR011410 NDK7

    Graphical View of Domain Structure for InterPro Entry Q9Y5B8

    ProtoNet protein and cluster: Q9Y5B8

    2 Blocks protein families:
    IPB001564 Nucleoside diphosphate kinase
    IPB006602 Protein of unknown function DM10


    UniProtKB/Swiss-Prot: NDK7_HUMAN, Q9Y5B8
    Similarity: Belongs to the NDK family
    Similarity: Contains 1 DM10 domain


    Function
    for NME7 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDK7_HUMAN, Q9Y5B8
    Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is
    transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
    Catalytic activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate

         Enzyme Number (IUBMB): EC 2.7.4.61 2

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004550nucleoside diphosphate kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0046872metal ion binding IEA--
         
    NME7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NME7:
     Decreased Salmonella enterica  

         7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Nme7):
     behavior/neurological  craniofacial  growth/size  nervous system  reproductive system 
     respiratory system  skeleton 

    NME7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for NME7 

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): NME7
    Browse MicroRNA Expression Plasmids
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate NME7 (see all 12):
    hsa-miR-301b hsa-miR-301a hsa-miR-3666 hsa-miR-19b hsa-miR-454 hsa-miR-4295 hsa-miR-3908 hsa-miR-130a
    SwitchGear 3'UTR luciferase reporter plasmid: NME7 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NME7 (see all 7)
    OriGene shRNA RFP: NME7
    OriGene siRNA: NME7
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    Sirion Biotech Custom design and validation of potent shRNA sequences against NME7 

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of NME7 
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NME7 (see all 6)
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    GenScript: all cDNA clones in your preferred vector (see all 2): NME7 (NM_013330)
    Browse Sino Biological Human cDNA Clones
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NME7


    Pathways & Interactions
    for NME7 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1pyrimidine ribonucleotides interconversion
    		pyrimidine ribonucleotides interconversion1.00
    		pyrimidine deoxyribonucleotides de novo biosynthesis I0.50
    		pyrimidine ribonucleotides de novo biosynthesis0.88
    		salvage pathways of pyrimidine ribonucleotides0.45
    2Purine metabolism
    		Purine metabolism1.00
    		Pyrimidine metabolism0.38
    3ATP/ITP metabolism
    		ATP/ITP metabolism1.00
    		ATP/ITP metabolism0.98
    4Metabolism
    		Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NME7
        ATP/ITP metabolism


    1 GeneGo (Thomson Reuters) Pathway for NME7
        ATP/ITP metabolism

    4 BioSystems Pathways for NME7 
        pyrimidine ribonucleotides interconversion
    pyrimidine ribonucleotides de novo biosynthesis
    salvage pathways of pyrimidine ribonucleotides
    pyrimidine deoxyribonucleotides de novo biosynthesis I


    3         Kegg Pathways  (Kegg details for NME7):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways


    NME7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NME7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/105 Interacting proteins for NME7 (Q9Y5B82, 3 ENSP000003567854) via UniProtKB, MINT, STRING, and/or I2D (see all 105)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRT18P057832, 3, ENSP000003734874MINT-68025 I2D: score=5 STRING: ENSP00000373487
    NT5C2P499022, 3, ENSP000003394794MINT-67114 I2D: score=5 STRING: ENSP00000339479
    TCHPQ9BT922, 3, ENSP000003244044MINT-67218 I2D: score=5 STRING: ENSP00000324404
    FKBP6O753442, 3, ENSP000002520374MINT-66560 I2D: score=5 STRING: ENSP00000252037
    ZNF263O149782, 3, ENSP000002190694MINT-68026 I2D: score=5 STRING: ENSP00000219069
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003351epithelial cilium movement IEA--
    GO:0006183GTP biosynthetic process IEA--
    GO:0006228UTP biosynthetic process IEA--
    GO:0006241CTP biosynthetic process IEA--
    GO:0007368determination of left/right symmetry IEA--

    NME7 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NME7 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NME7

    10/21 HMDB Compounds for NME7 (see all 21)    About this table
    CompoundSynonyms CAS #PubMed Ids
    2'-Deoxyinosine triphosphate2'-Deoxyinosine-5'-triphosphate (see all 6)16595-02-1--
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    CDPCDP (see all 3)63-38-7--
    Cytidine triphosphatecytidine 5'-(tetrahydrogen triphosphate) (see all 15)65-47-4--
    Deoxyuridine triphosphate2'-Deoxyuridine-5'-triphosphorate (see all 9)1173-82-6--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    IDP5'-IDP (see all 10)86-04-4--
    Inosine triphosphateinosine 5'-(tetrahydrogen triphosphate) (see all 13)132-06-9--
    Search CenterWatch for drugs/clinical trials and news about NME7 / NDK7 

    Transcripts
    for NME7 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NME7 gene (2 alternative transcripts): 
    NM_013330.3  NM_197972.1  

    Unigene Cluster for NME7:

    NME/NM23 family member 7
    Hs.706952  [show with all ESTs]
    Unigene Representative Sequence: AB209049
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000530739 ENST00000493481 ENST00000472647 ENST00000367811(uc001gft.3 uc001gfu.3)
    ENST00000525440(uc010plq.2) ENST00000483228 ENST00000528517 ENST00000480478
    ENST00000524967(uc001gfv.1) ENST00000469474 ENST00000485609 ENST00000472984
    ENST00000491225 ENST00000527460

    miRNA
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate NME7 (see all 12):
    hsa-miR-301b hsa-miR-301a hsa-miR-3666 hsa-miR-19b hsa-miR-454 hsa-miR-4295 hsa-miR-3908 hsa-miR-130a
    SwitchGear 3'UTR luciferase reporter plasmid: NME7 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AB209049.1 AF153191.2 AK094513.1 AK290701.1 AK301917.1 BC006983.1 

    12 DOTS entries:

    DT.100683403  DT.95189651  DT.100892664  DT.95093688  DT.100031160  DT.92036054  DT.100031161  DT.100892669 
    DT.100892683  DT.121401656  DT.40133655  DT.95361855 

    24/166 AceView cDNA sequences (see all 166):

    AA514770 AI963388 BQ921304 AI094580 BU785499 AA910949 AA885915 AW173786 
    AA825320 AA854048 BQ637276 AL521119 AI803426 CR599535 AL038657 NM_197972 
    AK094513 AA855143 BG200642 BM717235 BQ631375 BU726084 W32856 BM669277 

    GeneLoc Exon Structure


    Expression
    for NME7 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NME7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GATTTTGCAC
    NME7 Expression
    About this image

    NME7 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NME7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NME7

    SOURCE GeneReport for Unigene cluster: Hs.706952
        SABiosciences Custom PCR Arrays for NME7
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NME7

    Orthologs
    for NME7 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NME7 gene from 9/35 species (see all 35)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves NME71 NME/NM23 family member 7 76.6(n)
    78.72(a)    		   100858145  XM_003640457.1  XP_003640505.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NME76
    --
    		 --
    		 64(a)
    15(a)
    		 1 ↔ 1
    possible ortholog
    		 3(175559948-175621542)
    2(117754712-117771891)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia MGC756772 hypothetical protein MGC75677 75.37(n)    BC061605.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii ndpkz42 nucleoside diphosphate kinase-Z4 71.48(n)   30086  BC049398.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta nmdyn-D71 , 3 nucleoside-diphosphate kinase3
    CG8362-PA1    		 43(a)3
    48.94(n)1
    42.15(a)1    		   3 85E43
    411741  NM_141669.21  NP_649926.21 
    worm
    (Caenorhabditis elegans)    		 Secernentea ndk-16
    		 Nucleoside diphosphate kinase
    		 28(a)
    		 possible ortholog
    		 I(10553101-10553902)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons NDPK16
    NDPK26
    (see all 5)    		 nucleoside diphosphate kinase II
    (see all 5)    		 28(a)
    20(a)
    (see all 5)    		 possible ortholog
    possible ortholog
    (see all 5)    		 4(5923400-5924532)
    5(25371904-25373861)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 nucleoside diphosphate kinase, putative, expressed...
    nucleoside diphosphate kinase, putative, expressed...
    (see all 4)    		 29(a)
    21(a)
    (see all 4)    		 possible ortholog
    possible ortholog
    (see all 4)    		 7(18333879-18336494)
    10(22186387-22188912)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria ndk6
    		 multifunctional nucleoside diphosphate kinase and ...
    		 34(a)
    		 1 → many
    		 Chromosome(2642455-2642886)


    ENSEMBL Gene Tree for NME7 (if available)
    TreeFam Gene Tree for NME7 (if available) 

    Paralogs
    for NME7 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NME7 gene
    NME12  NME22  NME32  NME82  NME42  NME1-NME22  NME62  NME92  
    NME52  
    8 SIMAP similar genes for NME7 using alignment to 3 protein entries:     NDK7_HUMAN (see all proteins):
    NME5    NME6    c371H6.2    NME3    NME4    NME2
    NME1    NME2P1

    NME7 for paralogs           About GeneDecksing



    Genomic Variants
    for NME7 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4101 NCBI SNPs in NME7 are shown (see all 4101)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs711217241,2
    		C--169102485(-) AAGCTGA/-TTTTT 2 -- int12Minor allele frequency- -:0.00NA CSA 4
    rs1378678141,2
    		--169102591(+) GAAACA/GGAAAC 2 -- int10--------
    rs802697481,2
    		C,F--169102601(+) CCTTTC/TGCAAA 2 -- int11Minor allele frequency- T:0.03WA 118
    rs37532931,2
    		C,A--169102690(+) ACAGAC/TCTGGA 2 -- int18Minor allele frequency- T:0.47NA CSA WA EA 367
    rs1127503561,2
    		C--169102705(+) ATGGCC/TGTTTT 2 -- int12Minor allele frequency- T:0.13WA 120
    rs758245301,2
    		C--169102787(+) TCGTTC/TTGCTA 2 -- int10--------
    rs775770541,2
    		C--169102788(+) CGTTTA/TGCTAT 2 -- int10--------
    rs1434240101,2
    		--169102818(+) GTGATG/TCGAAA 2 -- int10--------
    rs1439094351,2
    		--169102865(+) AAATAG/TCAAGG 2 -- int10--------
    rs1810395021,2
    		--169102976(+) CTACAG/TGAAAC 2 -- int10--------

    HapMap Linkage Disequilibrium report for NME7 (169101769 - 169337205 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 17 variations for NME7
         12 CNVs: 9899 48172 65206 84648 48171 58347 38020 48173 9381 6796 84647 54015
         5 Indels: 60904 23999 23998 42733 11007

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    Disorders / Diseases
    for NME7 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NME7 for disorders           About GeneDecksing

    OMIM gene information: 613465    OMIM disorders: --

    8 diseases for NME7:    About MalaCards
    ciliary dyskinesia    primary ciliary dyskinesia    situs inversus    essential hypertension
    hypertension    t-cell leukemia    pneumonia    leukemia

    1 disease from the University of Copenhagen DISEASES database for NME7:
    Primary ciliary dyskinesia
    Human Genome Epidemiology (HuGE) Navigator: NME7 (4 documents)

    Export disorders for NME7 gene to outside databases

    Publications
    for NME7 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NME7 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with NME7)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Nme protein family evolutionary history, a vertebrate perspective. (PubMed id 19852809)1, 3 Desvignes T....Bobe J. (2009)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    6. A genome-wide association study of venous thromboembol ism identifies risk variants in chromosomes 1q24.2 and 9q. (PubMed id 22672568)1 Heit J.A....De Andrade M. (2012)
    7. Genetics of venous thrombosis: insights from a new gen ome wide association study. (PubMed id 21980494)1 Germain M....Morange P.E. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Genetic predictors of fibrin D-dimer levels in health y adults. (PubMed id 21502573)1 Smith N.L....Hayward C. (2011)

    External Searches for NME7 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NME7 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29922 HGNC: 20461 AceView: NME7 Ensembl:ENSG00000143156 euGenes: HUgn29922
    ECgene: NME7 Kegg: 29922 H-InvDB: NME7

    Other Databases showing NME7 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NME7 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NME7 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NME7 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NME7 gene:
    Search GeneIP for patents involving NME7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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