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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NME5 Gene

protein-coding   GIFtS: 55
GCID: GC05M137451

NME/NM23 family member 5

(Previous names: non-metastatic cells 5, protein expressed in (nucleoside-diphosphate...)
 Explore 1 disease affiliated with
NME5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NME5    

Aliases
for NME5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
NME/NM23 Family Member 51 2     NDK-H 52 3
RSPH231 2     NDP Kinase Homolog 52 3
Non-Metastatic Cells 5, Protein Expressed In (Nucleoside-Diphosphate Kinase)1 2     NM23H52 5
Nm23-H51     NM23-H52
Inhibitor Of P53-Induced Apoptosis-Beta2 3     Nucleoside Diphosphate Kinase Homolog 52
Testis-Specific Nm23 Homolog2 3     Radial Spoke 23 Homolog2
IPIA-Beta1     

External Ids:    HGNC: 78531   Entrez Gene: 83822   Ensembl: ENSG000001129817   OMIM: 6035755   UniProtKB: P565973   

Export aliases for NME5 gene to outside databases

Previous GC identifers: GC05M137326 GC05M138126 GC05M137481 GC05M137527 GC05M137478 GC05M132641


Summaries
for NME5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NDK5_HUMAN, P56597
Function: Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular
levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of
late-stage spermatids to eliminate reactive oxygen species (By similarity)




Genomic Views
for NME5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NME5 gene promoter:
         Max1   AML1a   Pax-2   IRF-1   Pax-2a   FOXL1   C/EBPalpha   AREB6   Pax-2b   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NME5 promoter sequence
   Search SABiosciences Chromatin IP Primers for NME5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NME5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31   Ensembl cytogenetic band:  5q31.2   HGNC cytogenetic band: 5q31.2

NME5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME5 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M137451:  view genomic region     (about GC identifiers)

Start:
 137,450,861 bp from pter      End:
 137,475,132 bp from pter
Size:
 24,272 bases      Orientation:
 minus strand

Proteins
for NME5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NDK5_HUMAN, P56597 (See protein sequence)
Recommended Name: Nucleoside diphosphate kinase homolog 5  
Size: 212 amino acids; 24236 Da
Secondary accessions: B2R5G7

Explore the universe of human proteins at neXtProt for NME5: NX_P56597

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P56597

    • NME5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003542.1  
    ENSEMBL proteins: 
     ENSP00000265191  

    Human Recombinant Protein Products: 
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    Novus Biologicals NME5 Lysates
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    Uscn Proteins for NME5

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--


    NME5 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NME5

    Protein Domains /
    Families
    for NME5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NME5 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001564 Nucleoside_diP_kinase
     IPR007858 Dpy-30_motif
     IPR012410 NDK_H5

    Graphical View of Domain Structure for InterPro Entry P56597

    ProtoNet protein and cluster: P56597

    2 Blocks protein families:
    IPB001564 Nucleoside diphosphate kinase
    IPB007858 Dpy-30


    UniProtKB/Swiss-Prot: NDK5_HUMAN, P56597
    Similarity: Belongs to the NDK family


    Function
    for NME5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NDK5_HUMAN, P56597
    Function: Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular
    levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of
    late-stage spermatids to eliminate reactive oxygen species (By similarity)

         Genatlas biochemistry entry for NME5:
    non-metastatic cells 5,protein,with a nm23 nucleoside diphosphate kinase gene family,specifically expressed in testis
    germinal cells,expressed in germ cell,kidney,ovary,parathyroid,testis,uterus,involved in the phosphorylation of
    nucleoside diphosphates and putatively in spermatogenesis

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NME5
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate NME5:
    hsa-miR-433 hsa-miR-3658 hsa-miR-374b hsa-miR-375 hsa-miR-2116 hsa-miR-374a hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmid: NME5 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NME5 (see all 4)
    OriGene shRNA RFP: NME5
    OriGene siRNA: NME5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NME5

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NME5 (see all 3)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NME5 

    Cell Line
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    Search LifeMap BioReagents cell lines for NME5

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NME5

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004550nucleoside diphosphate kinase activity IEA--
    GO:0005524ATP binding IEA--


    NME5 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NME5:
     Increased cell death in HCT116 

    Animal Models:
         Mouse knock-out Nme5tm1Lex for NME5
         7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Nme5):
     cardiovascular system  craniofacial  growth/size  nervous system  reproductive system 
     respiratory system  skeleton 

    NME5 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NME5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1pyrimidine ribonucleotides interconversion
    		pyrimidine ribonucleotides interconversion1.00
    		pyrimidine deoxyribonucleotides de novo biosynthesis I0.50
    		pyrimidine ribonucleotides de novo biosynthesis0.88
    		salvage pathways of pyrimidine ribonucleotides0.45
    2Purine metabolism
    		Purine metabolism1.00
    		Pyrimidine metabolism0.38
    3Metabolism
    		Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4 BioSystems Pathways for NME5 
        pyrimidine ribonucleotides de novo biosynthesis
    pyrimidine ribonucleotides interconversion
    salvage pathways of pyrimidine ribonucleotides
    pyrimidine deoxyribonucleotides de novo biosynthesis I


    3         Kegg Pathways  (Kegg details for NME5):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways


    NME5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NME5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/94 Interacting proteins for NME5 (P565972, 3 ENSP000002651914) via UniProtKB, MINT, STRING, and/or I2D (see all 94)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYDC1Q8WWB32, 3, ENSP000003612764MINT-66095 I2D: score=4 STRING: ENSP00000361276
    DYDC2Q96IM93, ENSP000002560394I2D: score=4 STRING: ENSP00000256039
    RELAQ042062, ENSP000003842734MINT-8307338 STRING: ENSP00000384273
    NFS1Q9Y6973I2D: score=1 
    AK7ENSP000002675844STRING: ENSP00000267584
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003351epithelial cilium movement IEA--
    GO:0006165nucleoside diphosphate phosphorylation ----
    GO:0006183GTP biosynthetic process IEA--
    GO:0006228UTP biosynthetic process IEA--
    GO:0006241CTP biosynthetic process IEA--


    NME5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NME5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NME5
    Search CenterWatch for drugs/clinical trials and news about NME5 / NDK5 

    Transcripts
    for NME5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NME5 gene: 
    NM_003551.2  

    Unigene Cluster for NME5:

    NME/NM23 family member 5
    Hs.730856  [show with all ESTs]
    Unigene Representative Sequence: NM_003551
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265191(uc003lce.3) ENST00000506657 ENST00000514481 ENST00000508252
    ENST00000511353 ENST00000512954

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NME5
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate NME5:
    hsa-miR-433 hsa-miR-3658 hsa-miR-374b hsa-miR-375 hsa-miR-2116 hsa-miR-374a hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmid: NME5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NME5 (see all 4)
    OriGene shRNA RFP: NME5
    OriGene siRNA: NME5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NME5
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NME5 (NM_003551)
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NME5

    Additional cDNA sequence: 

    AF067724.1 AK312181.1 BC026182.2 U90450.1 Y14992.1 

    3 DOTS entries:

    DT.415225  DT.120861062  DT.91808619 

    24/69 AceView cDNA sequences (see all 69):

    AI367603 AA434444 AA477747 AA292811 AA400478 NM_003551 W39101 AF067724 
    AA393878 BC026182 AA453579 AL043779 BM968993 BU677743 BX100052 AA400452 
    AI364955 AI796075 AL043778 AA477853 AA431789 BM979998 AA876243 AA405301 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NME5    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b
    SP1:                                -                                 
    SP2:              -                 -                                 
    SP3:                                                                  


    ECgene alternative splicing isoforms for NME5

    Expression
    for NME5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NME5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTCAGATAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NME5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeOuter Nuclear LayerMature Rod CellsPhotoreceptors, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)

    See NME5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NME5

    SOURCE GeneReport for Unigene cluster: Hs.730856

    UniProtKB/Swiss-Prot: NDK5_HUMAN, P56597
    Tissue specificity: Specifically expressed in testis germinal cells

        SABiosciences Expression via Pathway-Focused PCR Arrays including NME5: 
              Nitric Oxide Signaling Pathway in human mouse rat
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for NME5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NME5 gene from 10/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nme51 , 5 non-metastatic cells 5, protein expressed in (nucleoside-diphosphate more5
    NME/NM23 family member 51    		 83.57(n)1
    86.26(a)1    		   18 (18.69 cM)5
    755331  NM_080637.31  NP_542368.21 
     345626345 
    chicken
    (Gallus gallus)    		 Aves NME51 non-metastatic cells 5, protein expressed in (nucleoside-diphosphate more 71.43(n)
    74.29(a)    		   426732  XM_003642079.1  XP_003642127.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NME56
    --
    (see all 3)    		 --
    		 79(a)
    39(a)
    (see all 3)    		 1 ↔ 1
    possible ortholog
    (see all 3)    		 GL344505.1(2106-10559)
    6(47767459-47772252)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.179972 Xenopus laevis transcribed sequence with moderate similarity more 73.57(n)    BX851959.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.144392 Transcribed sequence with weak similarity to protein more 75.68(n)    BI672891.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta awd6
    		 abnormal wing discs
    		 23(a)
    		 possible ortholog
    		 3R(27570894-27571706)
    worm
    (Caenorhabditis elegans)    		 Secernentea ndk-16
    		 Nucleoside diphosphate kinase
    		 28(a)
    		 possible ortholog
    		 I(10553101-10553902)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G174101 nucleoside diphosphate kinase-like protein 49.88(n)
    44.44(a)    		   838313  NM_101602.3  NP_173184.2 
    rice
    (Oryza sativa)    		 Liliopsida Os02g05651001 hypothetical protein 49.25(n)
    46.27(a)    		   4329701  NM_001053699.1  NP_001047164.1 
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria ndk6
    		 multifunctional nucleoside diphosphate kinase and ...
    		 36(a)
    		 1 → many
    		 Chromosome(2642455-2642886)


    ENSEMBL Gene Tree for NME5 (if available)
    TreeFam Gene Tree for NME5 (if available) 

    Paralogs
    for NME5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NME5 gene
    NME12  NME22  NME32  NME82  NME72  NME42  NME1-NME22  NME62  
    NME92  
    3 SIMAP similar genes for NME5 using alignment to 1 protein entry:     NDK5_HUMAN:
    NME7    NME6    NME8

    NME5 for paralogs           About GeneDecksing



    Genomic Variants
    for NME5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/357 NCBI SNPs in NME5 are shown (see all 357)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs349360681,2
    		C--132666019(+) CTCTAG/AGTCCG 1 -- ds50011Minor allele frequency- A:0.00NA 2
    rs176377201,2
    		C,F,H,--132666079(+) AGTACT/GCACCT 1 -- ds50019Minor allele frequency- G:0.02NA NS 940
    rs1867296931,2
    		--137450372(+) TCAGCC/TAACAA 1 -- int10--------
    rs2010636901,2
    		--137450421(+) TCTCT-/CTTTTT 1 -- int10--------
    rs131856441,2
    		C,F,H,--137450422(+) TCTCTT/CTTTTT 1 -- int116Minor allele frequency- C:0.41NS EA NA WA CSA 1980
    rs1812210571,2
    		--137450878(+) TCTATC/TTTTTA 1 -- ut310--------
    rs623834931,2
    		--137450981(+) TATGGA/GCTACA 1 -- ut310--------
    rs1863641341,2
    		--137451050(+) ATATAA/GGATAT 1 -- ut310--------
    rs1426382701,2
    		--137451158(+) CTAGTA/GTTACA 1 -- ut310--------
    rs1901859571,2
    		--137451206(+) TTAATC/GTTATC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NME5 (137450861 - 137475132 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NME5: --

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    Disorders / Diseases
    for NME5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NME5 for disorders           About GeneDecksing

    OMIM gene information: 603575    OMIM disorders: --

    1 disease for NME5:    About MalaCards
    pneumonia


    Export disorders for NME5 gene to outside databases

    Publications
    for NME5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NME5 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NME5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells. (PubMed id 9742940)1, 2, 3, 9 Munier A.... Lacombe M.-L. (1998)
    2. Nme protein family evolutionary history, a vertebrate perspective. (PubMed id 19852809)1, 3 Desvignes T....Bobe J. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Transactivation of the human NME5 gene by Sp1 in pancr eatic cancer cells. (PubMed id 22564704)1 Li F....Zhang L. (2012)
    5. Shifted Transversal Design smart-pooling for high cov erage interactome mapping. (PubMed id 19447967)1 Xin X....Thierry-Mieg N. (2009)
    6. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility? (PubMed id 14499630)1 Munier A....Lacombe M.L. (2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    External Searches for NME5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NME5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8382 HGNC: 7853 AceView: NME5 Ensembl:ENSG00000112981 euGenes: HUgn8382
    ECgene: NME5 Kegg: 8382 H-InvDB: NME5

    Other Databases showing NME5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NME5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NME5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NME5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NME5 gene:
    Search GeneIP for patents involving NME5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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