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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NME3 Gene

protein-coding   GIFtS: 65
GCID: GC16M001820

NME/NM23 nucleoside diphosphate kinase 3

(Previous names: non-metastatic cells 3, protein expressed in )
 Explore 8 diseases affiliated with
NME3 via our new
 Human Malady Compendium 
Biological research products
for NME3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
NME/NM23 Nucleoside Diphosphate Kinase 31 2     EC 2.7.4.63 8
DR-Nm231     NM23H32 5
NM23-H31 2     NDPK-C2
Non-Metastatic Cells 3, Protein Expressed In1 2     C371H6.21
Nucleoside Diphosphate Kinase C2 3     NDP Kinase C2
NDPKC2 3     Nucleoside Diphosphate Kinase 32
NDK 32 3     Nm23-H31
NDP Kinase 32 3     

External Ids:    HGNC: 78511   Entrez Gene: 48322   Ensembl: ENSG000001030247   OMIM: 6018175   UniProtKB: Q132323   

Export aliases for NME3 gene to outside databases

Previous GC identifers: GC16M001837 GC16M001760


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NDK3_HUMAN, Q13232
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is
transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis

Gene Wiki entry for NME3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NME3 gene promoter:
         USF1   Tal-1   Pax-5   Olf-1   GATA-1   E47   YY1   Roaz   GATA-2   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNME3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NME3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NME3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16q13.3

NME3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M001820:  view genomic region     (about GC identifiers)

Start:
1,820,287 bp from pter      End:
1,821,731 bp from pter
Size:
1,445 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDK3_HUMAN, Q13232 (See protein sequence)
Recommended Name: Nucleoside diphosphate kinase 3  
Size: 169 amino acids; 19015 Da
Cofactor: Magnesium (By similarity)
Developmental stage: Preferentially expressed at early stages of myeloid differentiation of highly purified CD34+ cells
1 PDB 3D structure from and Proteopedia for NME3:
1ZS6 (3D)    
Secondary accessions: Q9BWH4

Explore the universe of human proteins at neXtProt for NME3: NX_Q13232

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13232

  • 4/5 DME Specific Peptides for NME3 (Q13232) (see all 5)
     PGTIRGD  KPDGVQR  HGSDSVE  REIALWF 

    NME3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002504.2  
    ENSEMBL proteins: 
     ENSP00000219302   ENSP00000456160   ENSP00000455271   ENSP00000455435   ENSP00000454498  

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    Novus Biologicals NME3 Lysate
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    ProSpec Recombinant Protein for NME3
    Uscn Proteins for NME3

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--


    NME3 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NME3 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023005 Nucleoside_diP_kinase_AS
     IPR001564 Nucleoside_diP_kinase

    Graphical View of Domain Structure for InterPro Entry Q13232

    ProtoNet protein and cluster: Q13232

    1 Blocks protein family: IPB001564 Nucleoside diphosphate kinase

    UniProtKB/Swiss-Prot: NDK3_HUMAN, Q13232
    Similarity: Belongs to the NDK family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NDK3_HUMAN, Q13232
    Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is
    transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis
    Catalytic activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate

         Genatlas biochemistry entry for NME3:
    non-metastatic cells 3,protein,with a nm23 nucleoside diphosphate kinase gene family,preferentially expressed at early
    stage of myeloid differentiation,involved in the phosphorylation of nucleoside diphophates,inhibiting granulocyte
    differentiation and inducing apoptosis

    Enzyme Number (IUBMB): EC 2.7.4.61 2

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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004550nucleoside diphosphate kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0046872metal ion binding IEA--


    NME3 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for NME3:
     Decreased focal adhesion (FA)   Decreased viability 

    Animal Models:
         Mouse knock-out Nme3tm1Bgh for NME3
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Nme3):
     reproductive system 

    NME3 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1pyrimidine ribonucleotides interconversion
    pyrimidine ribonucleotides interconversion1.00
    pyrimidine deoxyribonucleotides de novo biosynthesis I0.50
    pyrimidine ribonucleotides de novo biosynthesis0.88
    salvage pathways of pyrimidine ribonucleotides0.45
    2Purine metabolism
    Purine metabolism1.00
    Pyrimidine metabolism0.38
    3ATP/ITP metabolism
    ATP/ITP metabolism1.00
    ATP/ITP metabolism0.98
    4Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NME3
        ATP/ITP metabolism


    1 GeneGo (Thomson Reuters) Pathway for NME3
        ATP/ITP metabolism

    4 BioSystems Pathways for NME3 
        pyrimidine ribonucleotides de novo biosynthesis
    pyrimidine ribonucleotides interconversion
    salvage pathways of pyrimidine ribonucleotides
    pyrimidine deoxyribonucleotides de novo biosynthesis I


    3         Kegg Pathways  (Kegg details for NME3):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways


    NME3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NME3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/105 Interacting proteins for NME3 (Q132322, 3 ENSP000002193024) via UniProtKB, MINT, STRING, and/or I2D (see all 105)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NME2P223922, 3, ENSP000003655724MINT-64130 I2D: score=6 STRING: ENSP00000365572
    NME1P155312, 3, ENSP000000130344MINT-68402 I2D: score=6 STRING: ENSP00000013034
    NME1-NME2P223922, 3MINT-64130 I2D: score=6 
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2861202 MINT-2861221 I2D: score=3 STRING: ENSP00000357292
    SGTAO437652, 3, ENSP000002215664MINT-67252 I2D: score=5 STRING: ENSP00000221566
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006183GTP biosynthetic process IEA--
    GO:0006228UTP biosynthetic process IEA--
    GO:0006241CTP biosynthetic process IEA--
    GO:0006915apoptotic process IEA--
    GO:0006917induction of apoptosis TAS7638209


    NME3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for NME3

    9 HMDB Compounds for NME3    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    CDPCDP (see all 3)63-38-7--
    Cytidine triphosphatecytidine 5'-(tetrahydrogen triphosphate) (see all 15)65-47-4--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    MagnesiumMagnesium (see all 2)7439-95-4--
    Thymidine 5'-triphosphate2'-Deoxythymidine 5'-triphosphate (see all 13)365-08-2--
    dTDPDeoxy-tdp (see all 5)491-97-4--
    Search CenterWatch for drugs/clinical trials and news about NME3 / NDK3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NME3 gene: 
    NM_002513.2  

    Unigene Cluster for NME3:

    NME/NM23 nucleoside diphosphate kinase 3
    Hs.514065  [show with all ESTs]
    Unigene Representative Sequence: BU196357
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000219302(uc002cmm.3 uc010brv.3) ENST00000564628 ENST00000561637
    ENST00000567271 ENST00000568561 ENST00000563498 ENST00000566600 ENST00000563367
    ENST00000565379 ENST00000563854 ENST00000564252

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    Inhib. RNA
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    Additional cDNA sequence: 

    AK308663.1 BC000250.1 U29656.1 

    12 DOTS entries:

    DT.100782593  DT.445711  DT.100783150  DT.100783151  DT.91751817  DT.100783153  DT.91751819  DT.100783149 
    DT.97847568  DT.100700725  DT.120722422  DT.95102725 

    13 AceView cDNA sequences:

    BQ316455 NM_002513 CR605551 BQ316453 BM310157 CD615033 BC000250 BM309876 
    CD615039 U29656 CD615041 CD615036 CD615035 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for NME3 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e · 5f
    SP1:              -           -     -                             -                                       
    SP2:              -           -     -                             -                                       
    SP3:              -           -     -                       -     -                                       
    SP4:                          -     -                             -                                       
    SP5:                          -                                   -                                       


    ECgene alternative splicing isoforms for NME3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NME3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGGGTGGCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NME3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NME3

    SOURCE GeneReport for Unigene cluster: Hs.514065
        SABiosciences Expression via Pathway-Focused PCR Array including NME3: 
              Apoptosis 384HT in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NME3 gene from 9/36 species (see all 36)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NME31 non-metastatic cells 3, protein expressed in 76.33(n)
    75.15(a)
      416399  XM_414714.3  XP_414714.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    NME66
    (see all 4)
    --
    28(a)
    26(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    6(47767459-47772252)
    GL343765.1(46424-53449)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339762 Xenopus laevis transcribed sequence with moderate similarity more 75.39(n)    CB944254.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ndpkz32 nucleoside diphosphate kinase-Z3 72.41(n)   30085  AF202054.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta awd3 CTP biosynthesis nucleoside-diphosphate
    kinase
    66(a)   100D2   --
    worm
    (Caenorhabditis elegans)
    Secernentea F25H2.53 nucleoside diphosphate kinase 57(a)   I(10561041-10562106)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NDPK21 nucleoside diphosphate kinase II 52.48(n)
    52.7(a)
      836451  NM_125726.3  NP_568970.2 
    rice
    (Oryza sativa)
    Liliopsida Os12g05483001 hypothetical protein 56.53(n)
    54.73(a)
      4352460  NM_001073503.1  NP_001066971.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria ndk6
    multifunctional nucleoside diphosphate kinase and ...
    45(a)
    possible ortholog
    Chromosome(2642455-2642886)


    ENSEMBL Gene Tree for NME3 (if available)
    TreeFam Gene Tree for NME3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NME3 gene
    NME12  NME22  NME82  NME42  NME72  NME1-NME22  NME62  NME92  
    NME52  
    8 SIMAP similar genes for NME3 using alignment to 5 protein entries:     NDK3_HUMAN (see all proteins):
    c371H6.2    NME1    NME2    NME1-NME2    NME4    NME2P1
    NME7    NME6

    NME3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/66 NCBI SNPs in NME3 are shown (see all 66    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1430262571,2
    --1819822(+) TGCCCA/GCTGTG 3 -- ut31 int10--------
    rs124485201,2
    C,F,H,--1819835(+) CTGCTC/TCCAGG 3 -- int1 ut3122Minor allele frequency- T:0.10EA NS NA WA CSA 1631
    rs1828632641,2
    --1820177(+) TCCCTC/TGTCTG 3 -- int1 ut310--------
    rs1874641371,2
    --1820292(+) GCTCTC/GTATGT 3 -- int1 ut310--------
    rs1162314431,2
    C,F,--1820312(+) CTTAAC/TGTCGT 3 -- int1 ut311Minor allele frequency- T:0.02WA 118
    rs25753281,2
    C,F,H,--1820341(-) TTTCGG/ATTTGG 2 -- ds500115Minor allele frequency- A:0.01NS NA WA CSA EA 785
    rs1929488691,2
    --1820356(+) AACGAA/GGACTT 3 -- ut31 ds50010--------
    rs1838897681,2
    --1820375(+) AAAAAC/TGTTGG 3 -- ds5001 ut310--------
    rs1884669071,2
    --1820399(+) GGGCAA/CCAGGA 3 -- ds5001 ut310--------
    rs1470278871,2
    --1820428(+) CCAGGC/TGAGCC 3 -- ds5001 ut310--------

    HapMap Linkage Disequilibrium report for NME3 (1820287 - 1821731 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for NME3
         5 CNVs: 49667 29999 5329 49668 49666

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NME3 for disorders           About GeneDecksing

    OMIM gene information: 601817    OMIM disorders: --

    8 diseases for NME3:    About MalaCards
    squamous cell carcinoma    hematopoiesis    ataxia    neuroblastoma
    tuberculosis    carcinoma    malaria    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: NME3 (1 document)

    Export disorders for NME3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NME3 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with NME3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nme protein family evolutionary history, a vertebrate perspective. (PubMed id 19852809)1, 3 Desvignes T....Bobe J. (2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
    4. Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family. (PubMed id 9067290)1, 3 Martinez R....Calabretta B. (1997)
    5. Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. (PubMed id 7638209)1, 2 Venturelli D.... Calabretta B. (1995)
    6. Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene. (PubMed id 11277919)1, 9 Erent M....Lascu I. (2001)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4832 HGNC: 7851 AceView: NME3 Ensembl:ENSG00000103024 euGenes: HUgn4832
    ECgene: NME3 Kegg: 4832 H-InvDB: NME3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NME3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NME3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NME3 gene:
    Search GeneIP for patents involving NME3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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