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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NME1-NME2 Gene

protein-coding   GIFtS: 49
GCID: GC17P049230

NME1-NME2 readthrough

 Explore 4 diseases affiliated with
NME1-NME2 via our new
 Human Malady Compendium 
Biological research products
for NME1-NME2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
NME1-NME2 Readthrough1 2     NM23B3
NM23-LV1 2     C-Myc Purine-Binding Transcription Factor PUF3
NMELV1 2     Histidine Protein Kinase NDKB3
EC 2.7.4.63 8     NDK B3
NME1-NME2 Protein2     NDP Kinase B3
NME1-NME2 Readthrough Transcript2     Nm23-H21
EC 2.7.13.33     

External Ids:    HGNC: 335311   Entrez Gene: 6543642   Ensembl: ENSG000002436787   UniProtKB: P223923   
ORGUL members:         
NONCODE:n410202    

Export aliases for NME1-NME2 gene to outside databases

Previous GC identifers: GC17U900586 GC17P046586 GC17P044600


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NME1-NME2:
This locus represents naturally occurring read-through transcription between the neighboring NME1 and NME2 genes. The
significance of this read-through transcription and the function of the resulting protein product have not yet been
determined. Alternative splicing of this gene results in multiple transcript variants. (provided by RefSeq, Nov 2010)

UniProtKB/Swiss-Prot: NDKB_HUMAN, P22392
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by
interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically
(PubMed:8392752). Exhibits histidine protein kinase activity

Gene Wiki entry for NME1-NME2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NME1-NME2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): NME1-NME2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NME1-NME2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NME1-NME2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

NME1-NME2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME1-NME2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P049230:  view genomic region     (about GC identifiers)

Start:
49,230,920 bp from pter      End:
49,249,108 bp from pter
Size:
18,189 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDKB_HUMAN, P22392 (See protein sequence)
Recommended Name: Nucleoside diphosphate kinase B  
Size: 152 amino acids; 17298 Da
Cofactor: Magnesium (By similarity)
Subunit: Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6). Interacts with CAPN8 (By
similarity). Interacts with AKAP13
Subcellular location: Cytoplasm. Nucleus. Note=Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded
from the nucleolus
5 PDB 3D structures from and Proteopedia for NME1-NME2:
1NSK (3D)        1NUE (3D)        3BBB (3D)        3BBC (3D)        3BBF (3D)    
Secondary accessions: A8MWA3 Q1WM23 Q6LCT6
Alternative splicing: 2 isoforms:  P22392-1   P22392-2   (Based on a naturally occurring readthrough transcript which produces an NME1-NME2 fusion protein)

Explore the universe of human proteins at neXtProt for NME1-NME2: NX_P22392

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2 (NME1-NME2)
  • View neXtProt modification sites for NX_P22392

  • 4/11 DME Specific Peptides for NME1-NME2 (P22392) (see all 11)
     LWFKPEE  PGTIRGD  PFFPGLV  RFEQKGF 

    NME1-NME2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001018146.1  
    ENSEMBL proteins: 
     ENSP00000426976   ENSP00000425581   ENSP00000421064   ENSP00000426901   ENSP00000376886  
    Reactome Protein details: P22392
    Human Recombinant Protein Products: 
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    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005829cytosol ----
    GO:0030027lamellipodium ----


    NME1-NME2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NME1-NME2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023005 Nucleoside_diP_kinase_AS
     IPR001564 Nucleoside_diP_kinase

    Graphical View of Domain Structure for InterPro Entry P22392

    ProtoNet protein and cluster: P22392

    1 Blocks protein family: IPB001564 Nucleoside diphosphate kinase

    UniProtKB/Swiss-Prot: NDKB_HUMAN, P22392
    Similarity: Belongs to the NDK family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NDKB_HUMAN, P22392
    Function: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by
    interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically
    (PubMed:8392752). Exhibits histidine protein kinase activity
    Catalytic activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
    Catalytic activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine

    Enzyme Numbers (IUBMB): EC 2.7.4.61 2 EC 2.7.13.31

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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0004550nucleoside diphosphate kinase activity ----
    GO:0004673protein histidine kinase activity ----
    GO:0005515protein binding ----


    NME1-NME2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NME1-NME2:
     Increased G1 DNA content 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1pyrimidine ribonucleotides interconversion
    pyrimidine ribonucleotides interconversion1.00
    pyrimidine deoxyribonucleotides de novo biosynthesis I0.50
    pyrimidine ribonucleotides de novo biosynthesis0.88
    salvage pathways of pyrimidine ribonucleotides0.45
    2Purine metabolism
    Purine metabolism1.00
    Pyrimidine metabolism0.38
    3Nucleotide Metabolism
    Nucleotide Metabolism1.00
    4Validated targets of C-MYC transcriptional activation
    Validated targets of C-MYC transcriptional activation1.00
    5ATP/ITP metabolism
    ATP/ITP metabolism0.98

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NME1-NME2
        ATP/ITP metabolism

    5/6 BioSystems Pathways for NME1-NME2 (see all 6
        Nucleotide Metabolism
    Validated targets of C-MYC transcriptional activation
    pyrimidine ribonucleotides de novo biosynthesis
    pyrimidine ribonucleotides interconversion
    pyrimidine deoxyribonucleotides de novo biosynthesis I

    3        Reactome Pathways for NME1-NME2
        Metabolism of nucleotides
    Synthesis and interconversion of nucleotide di- and triphosphates
    Metabolism


    3         Kegg Pathways  (Kegg details for NME1-NME2):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways


    NME1-NME2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NME1-NME2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/230 Interacting proteins for NME1-NME2 (P223921, 2, 3 ENSP000003768864) via UniProtKB, MINT, STRING, and/or I2D (see all 230)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=4 
    HIST1H4BP628053I2D: score=4 
    HIST1H4CP628053I2D: score=4 
    HIST1H4DP628053I2D: score=4 
    HIST1H4EP628053I2D: score=4 
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006165nucleoside diphosphate phosphorylation ----
    GO:0006183GTP biosynthetic process ----
    GO:0006228UTP biosynthetic process ----
    GO:0006241CTP biosynthetic process ----
    GO:0006351transcription, DNA-dependent ----


    NME1-NME2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NME1-NME2
    Search CenterWatch for drugs/clinical trials and news about NME1-NME2 / NDKB 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NME1-NME2 gene: 
    NM_001018136.2  

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514264(uc002itl.3) ENST00000513177 ENST00000512737(uc002itm.3 uc021uae.1)
    ENST00000503064(uc002itn.3) ENST00000485076 ENST00000393190(uc002ito.3)
    ENST00000570801 ENST00000573262

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate NME1-NME2:
    hsa-miR-3673
    SwitchGear 3'UTR luciferase reporter plasmidNME1-NME2 3' UTR sequence
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    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NME1-NME2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NME1-NME2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NME1-NME2

    UniProtKB/Swiss-Prot: NDKB_HUMAN, P22392
    Tissue specificity: Ubiquitously expressed

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NME1-NME2 gene from 8/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NDK_CHICK6
    TXNDC36
    (see all 5)
    Uncharacterized protein
    (see all 5)
    92(a)
    5(a)
    (see all 5)
    1 ↔ 1
    possible ortholog
    (see all 5)
    18(5062096-5064054)
    2(46221676-46240899)
    lizard
    (Anolis carolinensis)
    Reptilia --
    NME66
    (see all 4)
    --
    30(a)
    21(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    6(47767459-47772252)
    GL343765.1(46424-53449)
    zebrafish
    (Danio rerio)
    Actinopterygii nme2b.11 non-metastatic cells 2b.1, protein (NM23B) expressed more 79.69(n)
    87.42(a)
      30083  NM_130926.1  NP_571001.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta awd1 abnormal wing discs 69.28(n)
    72.89(a)
      43739  NM_057413.4  NP_476761.2 
    worm
    (Caenorhabditis elegans)
    Secernentea ndk-16
    Nucleoside diphosphate kinase
    67(a)
    possible ortholog
    I(10553101-10553902)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G238951 Pleckstrin homology (PH) domain-containing protein 62.89(n)
    62(a)
      2745723  NM_001203888.1  NP_001190817.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g05954001 hypothetical protein 60.89(n)
    61.33(a)
      4339815  NM_001063050.1  NP_001056515.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria ndk6
    multifunctional nucleoside diphosphate kinase and ...
    42(a)
    possible ortholog
    Chromosome(2642455-2642886)


    ENSEMBL Gene Tree for NME1-NME2 (if available)
    TreeFam Gene Tree for NME1-NME2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NME1-NME2 gene
    NME12  NME22  NME32  NME82  NME62  NME42  NME72  NME92  
    NME52  
    6 SIMAP similar genes for NME1-NME2 using alignment to 1 protein entry:     Q32Q12_HUMAN:
    NME2    NME1    NME2P1    NME3    c371H6.2    NME4

    NME1-NME2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NME1-NME2
    PGOHUM00000240634 PGOHUM00000236733


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    9 NCBI SNPs in NME1-NME2 are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs800750321,2
    C,F,--49239999(+) CCCAGG/CAGTCC 2 -- int15Minor allele frequency- C:0.15NA WA EA 362
    rs355179131,2
    C,F,--49240037(+) ACTGTA/CCTTCA 2 -- int111Minor allele frequency- C:0.49NA WA CSA EA 372
    rs1461032921,2
    --49240080(+) AAAAAC/TATATC 2 -- int10--------
    rs47942091,2
    C,F,--49240131(+) GGGAGT/CGTGGG 2 -- int18Minor allele frequency- C:0.21NA CSA WA EA 367
    rs1831044711,2
    --49240400(+) TGAGAA/CCAGCC 2 -- int10--------
    rs1401270301,2
    --49240503(+) GAGGTA/GGGAGG 2 -- int10--------
    rs786043571,2
    F,--49240532(+) GTTGGA/TGCAGT 2 -- int11Minor allele frequency- T:0.03EA 120
    rs1494109391,2
    --49240662(+) GGTGGA/TCTACA 2 -- int10--------
    rs1448301681,2
    --49240670(+) ACACAC/TACCTG 2 -- int10--------

    HapMap Linkage Disequilibrium report for NME1-NME2 (49230920 - 49249108 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NME1-NME2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NME1-NME2 for disorders           About GeneDecksing

    4 diseases for NME1-NME2:    About MalaCards
    chronic interstitial cystitis    tuberculosis    malaria    mycobacterium tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for NME1-NME2:
    Interstitial cystitis     Chronic interstitial cystitis
    Human Genome Epidemiology (HuGE) Navigator: NME1-NME2 (1 document)

    Export disorders for NME1-NME2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NME1-NME2 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with NME1-NME2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV. (PubMed id 16442775)1, 2, 3 Valentijn L.J.... Versteeg R. (2006)
    2. Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. (PubMed id 8392752)1, 2 Postel E.H.... Ferrone C.A. (1993)
    3. Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. (PubMed id 1851158)1, 2 Gilles A.-M.... Lascu I. (1991)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Reversible histidine phosphorylation in mammalian cells: a teeter- totter formed by nucleoside diphosphate kinase and protein histidine phosphatase 1. (PubMed id 20946858)2 Wieland T.... Klumpp S. (2010)
    8. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
    9. Plakoglobin interacts with and increases the protein levels of metastasis suppressor Nm23-H2 and regulates the expression of Nm23-H1 . (PubMed id 20101217)1 Aktary Z....Pasdar M. (2010)
    10. Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 654364 HGNC: 33531 Ensembl:ENSG00000243678 euGenes: HUgn654364 ECgene: NME1-NME2 Kegg: 654364
    H-InvDB: NME1-NME2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NME1-NME2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NME1-NME2 gene:
    Search GeneIP for patents involving NME1-NME2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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