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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NME1-NME2 Gene

protein-coding   GIFtS: 43
GCID: GC17P049230

NME1-NME2 Readthrough

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 4

Aliases
NME1-NME2 Readthrough1 2     NME1-NME2 Readthrough Transcript2
NM23-LV2     EC 2.7.4.64
NMELV2     NME24
NME1-NME2 Protein2     

External Ids:    HGNC: 335311   Entrez Gene: 6543642   Ensembl: ENSG000002436787   UniProtKB: Q32Q124   
ORGUL members:    fRNAdb10:FR281927      
H-InvDB12:HIT000101220    
NCBI13:D28391    
NONCODE14:n410202      
RNAdb15:HIV2730    

Export aliases for NME1-NME2 gene to outside databases

Previous GC identifers: GC17U900586 GC17P046586 GC17P044600


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NME1-NME2 Gene:
This locus represents naturally occurring read-through transcription between the neighboring NME1 and NME2 genes.
The significance of this read-through transcription and the function of the resulting protein product have not
yet been determined. Alternative splicing of this gene results in multiple transcript variants. (provided by
RefSeq, Nov 2010)

GeneCards Summary for NME1-NME2 Gene: 
NME1-NME2 (NME1-NME2 readthrough) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with NME1-NME2 include chronic interstitial cystitis, and cystitis, and among its related super-pathways are Purine metabolism and adenosine deoxyribonucleotides de novo biosynthesis I. An important paralog of this gene is NME2.

Gene Wiki entry for NME1-NME2 Gene

fRNAdb sequence ontology for NME1-NME2:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

View fRNAdb secondary structures for NME1-NME2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NME1-NME2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): NME1-NME2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NME1-NME2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NME1-NME2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.3   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

NME1-NME2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NME1-NME2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P049230:  view genomic region     (about GC identifiers)

Start:
49,230,897 bp from pter      End:
49,249,108 bp from pter
Size:
18,212 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for NME1-NME2

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/TrEMBL: Q32Q12 (See protein sequence)
Recommended Name: Nucleoside diphosphate kinase  
Size: 292 amino acids; 32642 Da

Explore proteomics data for NME1-NME2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q32Q12

  • NME1-NME2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NME1-NME2 Protein Expression
    REFSEQ proteins: NP_001018146.1  
    ENSEMBL proteins: 
     ENSP00000426976   ENSP00000425581   ENSP00000421064   ENSP00000426901   ENSP00000376886  

    Human Recombinant Protein Products for NME1-NME2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion ----
    GO:0005829cytosol ----

    NME1-NME2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR023005 Nucleoside_diP_kinase_AS
     IPR001564 Nucleoside_diP_kinase

    Graphical View of Domain Structure for InterPro Entry Q32Q12

    ProtoNet protein and cluster: Q32Q12

    UniProtKB/TrEMBL: Q32Q12
    Similarity: Belongs to the NDK family


    NME1-NME2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/TrEMBL Summary: Q32Q12
    Catalytic activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate

         Enzyme Number (IUBMB): EC 2.7.4.61

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0004550nucleoside diphosphate kinase activity ----
    GO:0004673protein histidine kinase activity ----
    GO:0005515protein binding ----
         
    NME1-NME2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NME1-NME2:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NME1-NME2 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate NME1-NME2:
    hsa-miR-3673
    SwitchGear 3'UTR luciferase reporter plasmidNME1-NME2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NME1-NME2 About   (see all 6)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Purine metabolism
    Purine metabolism0.38
    ATP/ITP metabolism0.31
    Pyrimidine metabolism0.38
    2superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
    pyrimidine deoxyribonucleotides de novo biosynthesis I0.88
    adenosine deoxyribonucleotides de novo biosynthesis I0.73
    superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)0.88
    pyrimidine deoxyribonucleotides de novo biosynthesis II0.73
    pyrimidine deoxyribonucleotides biosynthesis from CTP0.88
    CMP phosphorylation0.73
    UTP and CTP de novo biosynthesis0.86
    superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis0.71
    3adenosine ribonucleotides de novo biosynthesis
    superpathway of purine nucleotides de novo biosynthesis I0.49
    4Metabolism
    Metabolic pathways0.40
    5Validated targets of C-MYC transcriptional activation
    Validated targets of C-MYC transcriptional activation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NME1-NME2
        ATP/ITP metabolism

    5/17 BioSystems Pathways for NME1-NME2 (see all 17)
        superpathway of pyrimidine ribonucleotides de novo biosynthesis
    Nucleotide Metabolism
    superpathway of purine nucleotides de novo biosynthesis I
    Validated targets of C-MYC transcriptional activation
    superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis


    3         Kegg Pathways  (Kegg details for NME1-NME2):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways


    NME1-NME2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NME1-NME2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/94 Interacting proteins for NME1-NME2 (ENSP000003768864) via UniProtKB, MINT, STRING, and/or I2D (see all 94)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADCY2ENSP000003429524STRING: ENSP00000342952
    AK1ENSP000003622494STRING: ENSP00000362249
    AK2ENSP000003469214STRING: ENSP00000346921
    CMPK1ENSP000003609394STRING: ENSP00000360939
    CTPS1ENSP000003616994STRING: ENSP00000361699
    About this table

    Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006165nucleoside diphosphate phosphorylation ----
    GO:0006183GTP biosynthetic process ----
    GO:0006228UTP biosynthetic process ----
    GO:0006241CTP biosynthetic process ----
    GO:0006351transcription, DNA-dependent ----

    NME1-NME2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NME1-NME2

    Search CenterWatch for drugs/clinical trials and news about NME1-NME2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    1 fRNAdb Secondary structure:


    REFSEQ mRNAs for NME1-NME2 gene: 
    NM_001018136.2  

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514264(uc002itl.3) ENST00000513177 ENST00000512737(uc002itm.3 uc021uae.1)
    ENST00000503064(uc002itn.3) ENST00000485076 ENST00000393190(uc002ito.3)
    ENST00000570801 ENST00000573262
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate NME1-NME2:
    hsa-miR-3673
    SwitchGear 3'UTR luciferase reporter plasmidNME1-NME2 3' UTR sequence
    Inhib. RNA
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      Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NME1-NME2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NME1-NME2

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NME1-NME2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NME1-NME2 Expression
    About this image


    See NME1-NME2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NME1-NME2
        SABiosciences Custom PCR Arrays for NME1-NME2
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NME1-NME2 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gm55661 , 5 predicted pseudogene 55661, 5 89.39(n)1
    94.81(a)1
      5 (89.18 cM)5
    4339681  XM_485703.51  XP_485703.21 
     1496607655 
    chicken
    (Gallus gallus)
    Aves NME26
    Nucleoside diphosphate kinase
    92(a)
    possible ortholog
    18(5038160-5040118)
    lizard
    (Anolis carolinensis)
    Reptilia NME16
    Nucleoside diphosphate kinase
    50(a)
    possible ortholog
    2(117749525-117771891)
    zebrafish
    (Danio rerio)
    Actinopterygii nme2b.11 non-metastatic cells 2b.1, protein (NM23B) expressed more 79.69(n)
    87.42(a)
      30083  NM_130926.1  NP_571001.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta awd1 abnormal wing discs 69.28(n)
    72.89(a)
      43739  NM_057413.4  NP_476761.2 
    worm
    (Caenorhabditis elegans)
    Secernentea ndk-16
    Protein NDK-1
    69(a)
    1 → many
    I(10553112-10553913)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YNK16
    Nucleoside diphosphate kinase, catalyzes the trans...
    59(a)
    1 → many
    XI(314812-315273)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G238951 Pleckstrin homology (PH) domain-containing protein 62.89(n)
    62(a)
      2745723  NM_001203888.1  NP_001190817.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g05954001 hypothetical protein 60.89(n)
    61.33(a)
      4339815  NM_001063050.1  NP_001056515.1 


    ENSEMBL Gene Tree for NME1-NME2 (if available)
    TreeFam Gene Tree for NME1-NME2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NME1-NME2 gene
    NME22  NME12  NME32  NME82  NME42  NME72  NME62  NME92  
    NME52  
    6 SIMAP similar genes for NME1-NME2 using alignment to 1 protein entry:     Q32Q12_HUMAN:
    NME2    NME1    NME2P1    NME3    c371H6.2    NME4

    NME1-NME2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NME1-NME2
    PGOHUM00000240634 PGOHUM00000236733


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/11 SNPs in NME1-NME2 are shown (see all 11)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs800750321,2
    C,F--49239999(+) CCCAGG/CAGTCC 2 -- int15Minor allele frequency- C:0.15NA WA EA 362
    rs355179131,2
    C,F--49240037(+) ACTGTA/CCTTCA 2 -- int111Minor allele frequency- C:0.49NA WA CSA EA 372
    rs1461032921,2
    --49240080(+) AAAAAC/TATATC 2 -- int10--------
    rs47942091,2
    C,F--49240131(+) GGGAGT/CGTGGG 2 -- int18Minor allele frequency- C:0.21NA CSA WA EA 367
    rs1831044711,2
    --49240400(+) TGAGAA/CCAGCC 2 -- int10--------
    rs1401270301,2
    C--49240503(+) GAGGTA/GGGAGG 2 -- int10--------
    rs786043571,2
    F--49240532(+) GTTGGA/TGCAGT 2 -- int11Minor allele frequency- T:0.03EA 120
    rs1494109391,2
    --49240662(+) GGTGGA/TCTACA 2 -- int10--------
    rs1448301681,2
    --49240670(+) ACACAC/TACCTG 2 -- int10--------
    rs3716444181,2
    ----49239959(+) TAGTCC/TAGCTA 2 -- int10--------

    HapMap Linkage Disequilibrium report for NME1-NME2 (49230897 - 49249108 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NME1-NME2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NME1-NME2
    DNA2.0 Custom Variant and Variant Library Synthesis for NME1-NME2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM information: 215500 601202 601251 605809 606579 607464 608631 609432 610185    
    4 diseases for NME1-NME2:    About MalaCards
    chronic interstitial cystitis    cystitis    tuberculosis    pneumonia

    1 disease from the University of Copenhagen DISEASES database for NME1-NME2:
    Interstitial cystitis

    NME1-NME2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NME1-NME2
    Human Genome Epidemiology (HuGE) Navigator: NME1-NME2 (1 document)

    Export disorders for NME1-NME2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NME1-NME2 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with NME1-NME2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV. (PubMed id 16442775)1, 3 Valentijn L.J.... Versteeg R. (2006)
    3. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 654364 HGNC: 33531 Ensembl:ENSG00000243678 euGenes: HUgn654364 ECgene: NME1-NME2 Kegg: 654364
    H-InvDB: NME1-NME2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NME1-NME2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NME1-NME2 gene:
    Search GeneIP for patents involving NME1-NME2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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