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NMD3 Gene

protein-coding   GIFtS: 54
GCID: GC03P160822

NMD3 Ribosome Export Adaptor

(Previous name: NMD3 homolog (S. cerevisiae))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NMD3 Ribosome Export Adaptor1 2
hNMD32 3
NMD3 Homolog (S. Cerevisiae)1
60S Ribosomal Export Protein NMD32
NMD3 Homolog2

External Ids:    HGNC: 242501   Entrez Gene: 510682   Ensembl: ENSG000001692517   OMIM: 6110215   UniProtKB: Q96D463   

Export aliases for NMD3 gene to outside databases

Previous GC identifers: GC03P162422 GC03P158337


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NMD3 Gene:
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm
through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1
(XPO1; MIM 602559) pathway (Trotta et al., 2003 (PubMed 12773398)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NMD3 Gene:
NMD3 (NMD3 ribosome export adaptor) is a protein-coding gene.

UniProtKB/Swiss-Prot: NMD3_HUMAN, Q96D46
Function: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit

Gene Wiki entry for NMD3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NMD3 gene promoter:
         AML1a   p53   Ik-3   HNF-1A   HNF-1   POU2F1a   POU2F1b   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNMD3 promoter sequence
   Search Chromatin IP Primers for NMD3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NMD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.1   Ensembl cytogenetic band:  3q26.1   HGNC cytogenetic band: 3q26.1

NMD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NMD3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P160822:  view genomic region     (about GC identifiers)

Start:
160,822,484 bp from pter      End:
160,971,320 bp from pter
Size:
148,837 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NMD3_HUMAN, Q96D46 (See protein sequence)
Recommended Name: 60S ribosomal export protein NMD3  
Size: 503 amino acids; 57603 Da
Subunit: Found in a 60S ribosomal subunit export complex with RAN and XPO1. Interacts with XPO1. Associates with
the 60S ribosomal subunit
Secondary accessions: D3DNM7 Q9Y2Z6

Explore the universe of human proteins at neXtProt for NMD3: NX_Q96D46

Explore proteomics data for NMD3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NMD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057022.2  
    ENSEMBL proteins: 
     ENSP00000418852   ENSP00000418980   ENSP00000419030   ENSP00000307525   ENSP00000417559  
     ENSP00000418908   ENSP00000419647   ENSP00000419004  

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    antibodies-online peptides for NMD3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007064 NMD3

    Graphical View of Domain Structure for InterPro Entry Q96D46

    ProtoNet protein and cluster: Q96D46

    1 Blocks protein domain: IPB007064 NMD3 family

    UniProtKB/Swiss-Prot: NMD3_HUMAN, Q96D46
    Similarity: Belongs to the NMD3 family


    Find genes that share domains with NMD3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NMD3_HUMAN, Q96D46
    Function: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with NMD3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for NMD3:
     Nuclear 60S biogenesis defects  Synthetic lethal with c-Myc af 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NMD3

    miRNA
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    miRTarBase miRNAs that target NMD3:
    hsa-mir-16-5p (MIRT051243), hsa-mir-193b-3p (MIRT016413), hsa-mir-92a-3p (MIRT048972), hsa-mir-484 (MIRT042015), hsa-mir-423-5p (MIRT038012), hsa-mir-26b-5p (MIRT029457), hsa-mir-155-5p (MIRT020746)

    Block miRNA regulation of human, mouse, rat NMD3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate NMD3:
    hsa-miR-607 hsa-miR-3662 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidNMD3 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NMD3_HUMAN, Q96D46: Cytoplasm. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Shuttles between the
    nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    cytoskeleton1
    extracellular1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm IEA--
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with NMD3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NMD3 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA transport
    RNA transport
    2Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes


    Find genes that share SuperPaths with NMD3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for NMD3):
        Ribosome biogenesis in eukaryotes
    RNA transport

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NMD3
    Interactions:

        Search GeneGlobe Interaction Network for NMD3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NMD3 (Q96D463 ENSP000003075254) via UniProtKB, MINT, STRING, and/or I2D (see all 250)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--

    Find genes that share ontologies with NMD3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NMD3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NMD3 gene: 
    NM_015938.3  

    Unigene Cluster for NMD3:

    NMD3 homolog (S. cerevisiae)
    Hs.598836  [show with all ESTs]
    Unigene Representative Sequence: AK094749
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000468606 ENST00000460503 ENST00000493066 ENST00000473909 ENST00000351193(uc003feb.1)
    ENST00000472947(uc003fec.3 uc010hwh.3) ENST00000463518 ENST00000476237
    ENST00000460469(uc003fed.1) ENST00000478160
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate NMD3:
    hsa-miR-607 hsa-miR-3662 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidNMD3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NMD3
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NMD3
      QuantiTect SYBR Green Assays in human, mouse, rat NMD3
      QuantiFast Probe-based Assays in human, mouse, rat NMD3

    Additional mRNA sequence: 

    AF132941.1 AK021775.1 AK024706.1 AK094749.1 AK225664.1 AK296710.1 AK308865.1 BC013317.1 

    16 DOTS entries:

    DT.312721  DT.91863039  DT.100780630  DT.95126351  DT.100780633  DT.40118028  DT.120873418  DT.100709289 
    DT.120873409  DT.92447739  DT.95247758  DT.120873386  DT.120873392  DT.121053518  DT.97768262  DT.95254327 

    Selected AceView cDNA sequences (see all 252):

    BC013317 AI004325 AI687171 AL559741 BM751006 AV703519 AI219257 AA282197 
    BF511033 AI355571 AW117998 BP379771 BU684937 BQ433999 AU100573 AV654197 
    CB177429 BE887436 CR591426 BF969556 BM999516 CB177800 AI284075 BU182440 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NMD3    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                    -     -                                   -                                                                     
    SP2:              -     -     -                                   -                                                                     
    SP3:                          -                                   -                                                                     
    SP4:              -     -     -                                                                                                         
    SP5:                                                                                                                                    


    ECgene alternative splicing isoforms for NMD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NMD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NMD3 Expression
    About this image


    NMD3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
    NMD3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NMD3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.598836
        Custom PCR Arrays for NMD3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NMD3 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nmd31 , 5 NMD3 homolog (S. cerevisiae)1, 5 91.39(n)1
    94.83(a)1
      3 (32.25 cM)5
    971121  NM_133787.21  NP_598548.11 
     697219855 
    chicken
    (Gallus gallus)
    Aves NMD31 NMD3 homolog (S. cerevisiae) 77(n)
    81.11(a)
      425009  XM_422813.4  XP_422813.2 
    lizard
    (Anolis carolinensis)
    Reptilia NMD36
    NMD3 ribosome export adaptor
    83(a)
    1 ↔ 1
    3(12587932-12607909)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF286018.12   -- 77.5(n)    CF286018.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nmd31 NMD3 homolog (S. cerevisiae) 69.65(n)
    77.49(a)
      541444  NM_001013569.2  NP_001013587.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nmd31 Nonsense-mediated mRNA 3 56.04(n)
    54.45(a)
      31195  NM_057984.4  NP_477332.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T25G3.31 T25G3.3 56.03(n)
    52.35(a)
      3565801  NM_059713.7  NP_492114.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NMD3(YHR170W)4
    NMD31
    Protein involved in nuclear export of the large ribosomal more4
    NMD31
    54.75(n)1
    47.45(a)1
      8(443828-445384)4
    8565751, 4  NP_012040.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G038201 AT2G03820 54.09(n)
    46.06(a)
      814908  NM_126428.2  NP_178476.1 
    rice
    (Oryza sativa)
    Liliopsida Os10g05739001 Os10g0573900 46.76(n)
    41.13(a)
      4349477  NM_001072005.1  NP_001065473.1 


    ENSEMBL Gene Tree for NMD3 (if available)
    TreeFam Gene Tree for NMD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NMD3 gene

    Find genes that share paralogs with NMD3           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for NMD3
    PGOHUM00000232726 PGOHUM00000232802


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NMD3 (see all 665)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1424044191,2
    C--160937106(+) TGACAA/GCATCC 1 -- us2k10--------
    rs1149875281,2
    C,F--160937158(+) AACACC/TCGCCC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs2014613431,2
    C--160937241(-) AGCCCA/GGACAC 1 -- us2k10--------
    rs1512923831,2
    C--160937252(+) CACTTC/TGAAGA 1 -- us2k10--------
    rs1405052921,2
    C--160937263(+) GTAATA/GAATAG 1 -- us2k10--------
    rs1891854191,2
    --160937342(+) AAAAAA/CCGGGG 1 -- us2k10--------
    rs745952311,2
    C,F--160937389(+) TAAATG/CGATAA 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1504245861,2
    --160937418(+) TTGAGC/GGTCTG 1 -- us2k10--------
    rs1476744071,2
    C--160937470(+) GACCCA/GAATTG 1 -- us2k10--------
    rs594980041,2
    C--160937498(+) ACTGCC/TGGGCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NMD3 (160822484 - 160971320 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NMD3: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NMD3
    DNA2.0 Custom Variant and Variant Library Synthesis for NMD3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611021    OMIM disorders: --


    Find genes that share disorders with NMD3           About GenesLikeMe

    Genetic Association Database (GAD): NMD3

    Export disorders for NMD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NMD3 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with NMD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates. (PubMed id 12773398)1, 2, 3, 9 Trotta C.R.... Dahlberg J.E. (EMBO J. 2003)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus and affect rRNA synthesis. (PubMed id 23782956)1, 3 Bai B....Laiho M. (Nucleus 2013)
    4. Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway. (PubMed id 12724356)1, 2 Thomas F. and Kutay U. (J. Cell Sci. 2003)
    5. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. A bead-based approach for large-scale identification of in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (Proteomics 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51068 HGNC: 24250 AceView: CGI-07 Ensembl:ENSG00000169251 euGenes: HUgn51068
    ECgene: NMD3 Kegg: 51068 H-InvDB: NMD3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NMD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NMD3 gene:
    Search GeneIP for patents involving NMD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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