NMBR Gene
protein-coding GIFtS: 62
GCID: GC06M142438
|
|
neuromedin B receptor
| |
Aliases
for NMBR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuromedin B Receptor1 2 | | Epididymis Tissue Protein Li 185a2 3 | | Neuromedin-B-Preferring Bombesin Receptor2 3 | | NMB-R2 3 | | Neuromedin-B Receptor2 |
Export aliases for NMBR gene to outside databasesPrevious GC identifers: GC06M142019 GC06M142243 GC06M142377 GC06M139962 |
Summaries
for NMBR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NMBR:
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and forgastrointestinal epithelial tissue. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NMBR_HUMAN, P28336Function: Receptor for neuromedin-B
 summary
for NMBR: Bombesin receptors are activated by the endogenous ligands gastrin-releasing peptide (GRP), neuromedin B
(NMB) and GRP18-27 (neuromedin C). Three subtypes of bombesin receptor are known: a GRP-preferring receptor
(BB1 receptor), a NMB-preferring receptor (BB2 receptor) and an orphan receptor (bb3 receptor). The
receptors are Gq/11-coupled and are involved in the regulation of many biological functions including
sensory transmission, thermoregulation, feeding, pituitary, gastric and pancreatic secretion. They may also
be involved in tissue development, proliferation and differentiation.
Gene Wiki entry for NMBR (Neuromedin B receptor)
|
Genomic Views
for NMBR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NMBR gene promoter:
p53 AML1a Pax-2 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 c-Ets-1 FAC1 Sox9
Other transcription factors
Search SABiosciences Chromatin IP Primers for NMBR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMBR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q21-qter Ensembl cytogenetic band: 6q24.1 HGNC cytogenetic band: 6q21-qterNMBR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M142438: view genomic region
(about GC identifiers)
Start:
|
142,379,467 bp from pter |
End:
|
142,409,936 bp from pter |
Size:
|
30,470 bases |
Orientation:
|
minus strand |
|
Proteins
for NMBR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NMBR_HUMAN, P28336 (See
protein sequence)Recommended Name: Neuromedin-B receptor Size: 390 amino acids; 43435 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: E9KL38 Q5VUK8Explore the universe of human proteins at neXtProt for NMBR: NX_P28336
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P28336
NMBR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002502.2
ENSEMBL proteins: ENSP00000258042 Reactome Protein details: P28336
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NMBR for ontologies About GeneDecksing
NMBR Antibody Products:
Assay Products for NMBR: |
Protein
Domains /
Families
for NMBR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NMBR for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P28336ProtoNet protein and cluster: P28336 2 Blocks protein families: IPB001556 Bombesin receptor signature IPB001642 Neuromedin B receptor signature
UniProtKB/Swiss-Prot: NMBR_HUMAN, P28336Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for NMBR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NMBR_HUMAN, P28336Function: Receptor for neuromedin-B Genatlas biochemistry entry for NMBR:neuromedin B receptor, G protein coupled receptor superfamily
Clone
Products: |  | EMD Millipore Clones for the Expression of NMBR | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NMBR (NM_002511) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NMBR | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMBR |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMBR |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004946 | bombesin receptor activity |
IEA | -- |
NMBR for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for NMBR:
Animal Models:
Mouse knock-out Nmbrtm1Hoh for NMBR
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Nmbr):
NMBR for phenotypes About GeneDecksing
|
Pathways & Interactions
for NMBR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | G alpha (q) signalling events | | | 4 | Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for NMBR
2  BioSystems Pathways for NMBR
5/8 
Reactome Pathways for NMBR (see all 8)
1 
Kegg Pathway (Kegg details for NMBR):
NMBR for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NMBR
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/124 Interacting proteins for NMBR (P283363 ENSP000002580424) via UniProtKB, MINT, STRING, and/or I2D (see all 124)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007186 | G-protein coupled receptor signaling pathway |
TAS | 1655761 | | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway |
TAS | 7838118 | | GO:0031989 | bombesin receptor signaling pathway |
-- | -- |
NMBR for ontologies About GeneDecksing
|
Drugs & Compounds
for NMBR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NMBR for compounds About GeneDecksing
Compounds for NMBR available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| GRP (human) | Endogenous GRP receptor agonist | [93755-85-2] | | Bombesin | Involved in gastrointestinal tract function | [31362-50-2] | | BIM 23042 | Selective neuromedin B receptor antagonist (NMB-R, BB1) | [111857-96-6] | | BIM 23127 | NMB receptor antagonist. Also U-II receptor antagonist | [160161-61-5] |
3 Novoseek chemical compound relationships for NMBR gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ranatensin |
88.2 |
1 |
8788416 (1) |
| inositol 1,4,5 trisphosphate |
19.8 |
1 |
8806106 (1) |
| calcium |
6.66 |
3 |
8813645 (1), 8806106 (1), 9857994 (1) |
Search CenterWatch for drugs/clinical trials and news about NMBR
|
Transcripts
for NMBR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NMBR gene: NM_002511.2 Unigene Cluster for NMBR: Neuromedin B receptor Hs.654478 [show with all ESTs]Unigene Representative Sequence: NM_0025112 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000480652 ENST00000258042(uc003qiu.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NMBR (NM_002511) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NMBR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMBR |
Additional cDNA sequence: BC095542.1 GU727635.1 M73482.1 1 DOTS entry: DT.311274 17 AceView cDNA sequences: F08115 CN834310 F06497 CN835866 CN832105 NM_002511 CN839321 M73482 AW104598 T09210 F02775 AI476439 CN835813 CN839451 Z41733 R49477 CN834265
GeneLoc Exon Structure
|
Expression
for NMBR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NMBR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGCAGGAAA
About this image
See NMBR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NMBR
SOURCE GeneReport for Unigene cluster: Hs.654478
UniProtKB/Swiss-Prot: NMBR_HUMAN, P28336Tissue specificity: Expressed in epididymis (at protein level)
SABiosciences Expression via Pathway-Focused PCR Arrays including NMBR:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NMBR
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NMBR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NMBR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NMBR | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMBR |
Orthologs
for NMBR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NMBR gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NMBR1 |
neuromedin B receptor |
73.83(n)
74.87(a) |
|
428610 XM_426167.2 XP_426167.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NMBR6 |
-- |
66(a) |
1 ↔ 1 |
1(203044663-203067610) |
zebrafish
(Danio rerio) |
Actinopterygii |
nmbrl1 |
neuromedin B receptor-like |
64.76(n)
70.3(a) |
|
561834 XM_685233.2 XP_690325.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG301063
CCHa2r1 |
G-protein coupled receptor protein signaling
pathway more3
CCHamide-2 receptor1 |
36(a)3
50.28(n)1
40.61(a)1 |
|
54D33
355351 NM_001169589.11 NP_001163060.11 |
ENSEMBL Gene Tree for NMBR (if available)
TreeFam Gene Tree for NMBR (if available) |
Paralogs
for NMBR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NMBR gene
- EDNRA2 GRPR2 GPR372 BRS32 EDNRB2 GPR37L12
9 SIMAP similar genes for NMBR using alignment to 2 protein entries: NMBR_HUMAN (see all proteins):GRPR BRS3 CCR3 GIR OPRL1 EDNRB
PRLHR EDNRA NPBWR1
NMBR for paralogs About GeneDecksing
|
Genomic Variants
for NMBR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NMBR (142379467 - 142409936 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NMBR: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMBR |
|
Disorders
/ Diseases
for NMBR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NMBR for disorders About GeneDecksing
OMIM gene information: 162341
OMIM disorders: --
10  diseases for NMBR: About MalaCardspancreatitis lung carcinoma epididymitis colon adenocarcinoma
lung cancer adenocarcinoma carcinoma glioblastoma
obesity hypoxia
9 Novoseek disease relationships for NMBR gene About this table
Human Genome Epidemiology (HuGE) Navigator: NMBR (3 documents)
Export disorders for NMBR gene to outside databases
|
Publications
for NMBR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NMBR gene, integrated from 9 sources (see all 70):
(articles sorted by number of sources associating them with NMBR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells. (PubMed id 1655761)1, 2, 9 Corjay M.H.... Battey J.F. (1991)
- Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins. (PubMed id 20736409)1, 2 Li J.... Liu Y. (2010)
- The fifth transmembrane segment of the neuromedin B receptor is critical for high affinity neuromedin B binding. (PubMed id 8392057)1, 9 Fathi Z....Battey J.F. (1993)
- Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor. (PubMed id 9632639)1, 9 Sainz E....Battey J.F. (1998)
- Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. (PubMed id 15528253)1, 9 Matusiak D....Benya R.V. (2005)
- Molecular cloning and characterization of receptors for the mammalian bombesin-like peptides. (PubMed id 8391296)1, 9 Giladi E....Spindel E.R. (1993)
- Four novel Loci (19q13, 6q24, 12q24, and 5q14) influe nce the microcirculation in vivo. (PubMed id 21060863)1 Ikram M.K....Wong T.Y. (2010)
- Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Stable association between G alpha(q) and phospholipase C beta 1 in living cells. (PubMed id 16754659)1 Dowal L....Scarlata S. (2006)
|
External Searches for NMBR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NMBR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NMBR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NMBR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NMBR | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NMBR gene:
Search GeneIP for patents involving NMBR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NMBR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NMBR | | OriGene shRNA RFP for NMBR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NMBR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NMBR | | | OriGene Protein Over-expression Lysate for NMBR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NMBR | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NMBR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NMBR | | OriGene Custom Protein Services for NMBR | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NMBR | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NMBR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NMBR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NMBR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NMBR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NMBR |
| |
 |  |  |  | |
| | | | Tocris compounds for NMBR |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | NMBR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NMBR |
|  |  |  | | | | ThermoFisher Antibodies for NMBR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NMBR |
|
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