Aliases for NMBR Gene
External Ids for NMBR Gene
Previous GeneCards Identifiers for NMBR Gene
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]
GeneCards Summary for NMBR Gene
NMBR (Neuromedin B Receptor) is a Protein Coding gene. Diseases associated with NMBR include small cell cancer of the lung, somatic and lung cancer. Among its related pathways are Signaling by GPCR and Interleukin receptor SHC signaling. GO annotations related to this gene include G-protein coupled receptor activity and bombesin receptor activity. An important paralog of this gene is EDNRB.
UniProtKB/Swiss-Prot for NMBR Gene
Receptor for neuromedin-B
Bombesin receptors are activated by the endogenous ligands gastrin-releasing peptide (GRP), neuromedin B (NMB) and GRP18-27 (neuromedin C). Three subtypes of bombesin receptor are known: BB1, BB2 and an orphan receptor (bb3).