NLRX1 Gene
protein-coding GIFtS: 53
GCID: GC11P119037
|
|
NLR family member X1
| |
Aliases
for NLRX1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NLR Family Member X11 2 | | NOD262 3 | | CLR11.31 2 3 5 | | NOD52 3 | | NOD91 2 3 5 | | DLNB262 | | Caterpiller Protein 11.32 3 | | NLR Family, X12 | | Nucleotide-Binding Oligomerization Domain Protein 262 3 | | NOD-Like Receptor X12 | | Nucleotide-Binding Oligomerization Domain Protein 52 3 | | Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat Containing X12 | | Nucleotide-Binding Oligomerization Domain Protein 92 3 | | |
Export aliases for NLRX1 gene to outside databasesPrevious GC identifers: GC11P118545 GC11P114978 |
Summaries
for NLRX1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NLRX1:
This gene encodes a member of the NLR family. Alternative splicing has been observed at this gene locus and twotranscript variants, encoding distinct isoforms, have been identified. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NLRX1_HUMAN, Q86UT6Function: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses,through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has noinhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminalkinase dependent signaling through the production of reactive oxygen species (PubMed:18219313)
Gene Wiki entry for NLRX1
|
Genomic Views
for NLRX1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NLRX1 gene promoter:
SRF Oct-B1 oct-B2 Pax-6 SRF (504 AA) LCR-F1 c-Ets-1 GATA-2 FOXL1 Ik-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for NLRX1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NLRX1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3NLRX1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P119037: view genomic region
(about GC identifiers)
Start:
|
119,037,277 bp from pter |
End:
|
119,054,725 bp from pter |
Size:
|
17,449 bases |
Orientation:
|
plus strand |
|
Proteins
for NLRX1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NLRX1_HUMAN, Q86UT6 (See
protein sequence)Recommended Name: NLR family member X1 precursor Size: 975 amino acids; 107616 Da
Subunit: Interacts with MAVS
Subcellular location: Mitochondrion outer membrane
Sequence caution: Sequence=BAB15075.1; Type=Erroneous initiation; Sequence=BAG51714.1; Type=Erroneous initiation;Note=Translation N-terminally extended; Sequence=BAG51714.1; Type=Erroneous termination; Positions=951;Note=Translated as Trp;
1 PDB 3D structure from  and Proteopedia  for NLRX1:3UN9 (3D)
Secondary accessions: A8K6Q1 B3KPK2 B3KTA2 Q7RTR3 Q96D51 Q9H724Alternative splicing: 2 isoforms: Q86UT6-1 Q86UT6-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NLRX1: NX_Q86UT6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86UT6
NLRX1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_078894.2 NP_733840.1
ENSEMBL proteins: ENSP00000400268 ENSP00000402801 ENSP00000402381 ENSP00000386851 ENSP00000292199 ENSP00000387334 ENSP00000433442 ENSP00000386858 Reactome Protein details: Q86UT6
Human Recombinant Protein Products for NLRX1:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
-- | -- | | GO:0005741 | mitochondrial outer membrane |
TAS | -- |
NLRX1 for ontologies About GeneDecksing
NLRX1 Antibody Products:
Assay Products for NLRX1: |
Protein
Domains /
Families
for NLRX1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NLRX1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86UT6ProtoNet protein and cluster: Q86UT6 UniProtKB/Swiss-Prot: NLRX1_HUMAN, Q86UT6Similarity: Belongs to the NLRP familySimilarity: Contains 7 LRR (leucine-rich) repeatsSimilarity: Contains 1 NACHT domain |
Function
for NLRX1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: NLRX1_HUMAN, Q86UT6Function: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses,through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has noinhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminalkinase dependent signaling through the production of reactive oxygen species (PubMed:18219313) Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
NLRX1 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for NLRX1:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Nlrx1):
NLRX1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Nlrx1tm1Jpyt for NLRX1
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NLRX1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRX1 |
|
Pathways & Interactions
for NLRX1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | | | 2 | Immune System | | | 3 | NF-kappaB Signaling | | | 4 | Measles | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for NLRX1
4 
Reactome Pathways for NLRX1
2 
Kegg Pathways (Kegg details for NLRX1):
NLRX1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NLRX1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/25 Interacting proteins for NLRX1 (Q86UT61, 3 ENSP000002921994) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019048 | virus-host interaction |
IEA | -- | | GO:0032480 | negative regulation of type I interferon production |
TAS | -- | | GO:0044419 | interspecies interaction between organisms |
-- | -- | | GO:0045087 | innate immune response |
TAS | -- |
NLRX1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NLRX1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NLRX1
Search CenterWatch for drugs/clinical trials and news about NLRX1
|
Transcripts
for NLRX1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NLRX1 gene (2 alternative transcripts): NM_024618.2 NM_170722.1 Unigene Cluster for NLRX1: NLR family member X1 Hs.524082 [show with all ESTs]Unigene Representative Sequence: BC11089014 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000482180 ENST00000454811 ENST00000449394 ENST00000422249 ENST00000474751
ENST00000409991 ENST00000292199(uc001pvu.3 uc001pvw.3) ENST00000481860(uc010rzc.1)
ENST00000409109(uc001pvx.3) ENST00000468765 ENST00000525863 ENST00000524562
ENST00000469103 ENST00000409265(uc001pvv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NLRX1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NLRX1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NLRX1 (NM_170722) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NLRX1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NLRX1 |
Additional cDNA sequence: AB094095.1 AK025131.1 AK056454.1 AK095247.1 AK225223.1 AK291716.1 AK303002.1 AL049456.1 AY245437.1 BC013199.1 BC023974.2 BC110890.1 BC128205.1 BX647705.1 EF452237.1 10 DOTS entries: DT.100782647 DT.407521 DT.97788856 DT.120723681 DT.99972735 DT.101976377 DT.100782646 DT.100022882 DT.91687673 DT.91969773 24/84 AceView cDNA sequences (see all 84): BM720988 CD368866 BE276372 BE305080 BC013199 AK056454 AL039249 AW474535 AI871860 BX505411 BU624297 AW474537 BX647705 BK001111 BC023974 BE304350 AB094095 NM_024618 BX505412 AI265868 AW474509 NM_170722 AL049456 AK025131
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for NLRX1 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | · | 2g | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | · | 3f | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 8h | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NLRX1
|
Expression
for NLRX1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NLRX1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCCTTTGC
About this image
See NLRX1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NLRX1
SOURCE GeneReport for Unigene cluster: Hs.524082
UniProtKB/Swiss-Prot: NLRX1_HUMAN, Q86UT6Tissue specificity: Ubiquitously expressed. Strongest expression in mammary gland, heart and muscle. Detected in HeLa,HEK293T, THP-1, HL-60, Raji and Jurkat cell lines (at protein level)
SABiosciences Expression via Pathway-Focused PCR Array including NLRX1:
Primer
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRX1 |
Orthologs
for NLRX1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NLRX1 gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for NLRX1 (if available)
TreeFam Gene Tree for NLRX1 (if available) |
Paralogs
for NLRX1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NLRX1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NLRX1 (119037277 - 119054725 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NLRX1: --
Human Gene Mutation Database (HGMD): NLRX1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NLRX1 |
|
Disorders
/ Diseases
for NLRX1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NLRX1 for disorders About GeneDecksing
OMIM gene information: 611947
OMIM disorders: --
2  diseases for NLRX1: About MalaCardsshigellosis influenza
Human Genome Epidemiology (HuGE) Navigator: NLRX1 (4 documents)
Export disorders for NLRX1 gene to outside databases
|
Publications
for NLRX1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NLRX1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with NLRX1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- NODs: intracellular proteins involved in inflammation and apoptosis. (PubMed id 12766759)1, 2, 3 Inohara N. and Nunez G. (2003)
- NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. (PubMed id 18219313)1, 2 Tattoli I.... Girardin S.E. (2008)
- NLRX1 is a regulator of mitochondrial antiviral immunity. (PubMed id 18200010)1, 2 Moore C.B.... Ting J.P.-Y. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Rare inborn errors associated with chronic hepatitis B virus infection. (PubMed id 22610944)1 Zhao Q....Wang Y. (2012)
- The mitochondrial proteins NLRX1 and TUFM form a compl ex that regulates type I interferon and autophagy. (PubMed id 22749352)1 Lei Y....Ting J.P. (2012)
- Structure and functional characterization of the RNA-b inding element of the NLRX1 innate immune modulator. (PubMed id 22386589)1 Hong M....Wilson I.A. (2012)
- Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3. (PubMed id 22718770)1 Ling A....Girardin S.E. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
|
External Searches for NLRX1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NLRX1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NLRX1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NLRX1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NLRX1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NLRX1 gene:
Search GeneIP for patents involving NLRX1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NLRX1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NLRX1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NLRX1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NLRX1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NLRX1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NLRX1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NLRX1 |
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| | Antibodies & Assays for NLRX1 |
| | | | Search Tocris compounds for NLRX1 |
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 | | | NLRX1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRX1 |
|  |  |  |  | | | | ThermoFisher Antibodies for NLRX1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NLRX1 |
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