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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NLRP6 Gene

protein-coding   GIFtS: 50
GCID: GC11P000269

NLR Family, Pyrin Domain Containing 6

(Previous names: NACHT, leucine rich repeat and PYD containing 6)
(Previous symbol: NALP6)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NLR Family, Pyrin Domain Containing 61 2     AVR2
NALP61 2 3 5     CLR11.42
PYPAF52 3 5     NAVR2
NACHT, Leucine Rich Repeat And PYD Containing 61 2     NAVR/AVR2
Angiotensin II/Vasopressin Receptor2 3     PAN32
PYRIN-Containing APAF1-Like Protein 52 3     NACHT, LRR And PYD Containing Protein 62
Leucine Rich Repeat And Pyrin Domain Containing 61     NACHT, LRR And PYD Domains-Containing Protein 62
Nucleotide-Binding Oligomerization Domain1     Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin
Domain Containing 62

External Ids:    HGNC: 229441   Entrez Gene: 1713892   Ensembl: ENSG000001748857   OMIM: 6096505   UniProtKB: P590443   

Export aliases for NLRP6 gene to outside databases

Previous GC identifer: GC11P000098


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NLRP6 Gene:
The protein encoded by this gene binds arginine-vasopressin and may be involved in the
arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates
inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against
tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B,
activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Feb 2013)

GeneCards Summary for NLRP6 Gene: 
NLRP6 (NLR family, pyrin domain containing 6) is a protein-coding gene. Diseases associated with NLRP6 include crohn's disease, and hepatitis b. GO annotations related to this gene include vasopressin receptor activity and ATP binding. An important paralog of this gene is NLRP4.

UniProtKB/Swiss-Prot: NALP6_HUMAN, P59044
Function: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose
and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as
an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow
recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of
colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful,
inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote
activation of NF-kappa-B and stimulate cAMP accumulation (By similarity)

Gene Wiki entry for NLRP6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NLRP6 gene promoter:
         AP-1   ATF-2   STAT5A   NF-kappaB   LCR-F1   HNF-4alpha1   AREB6   CRE-BP1   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNLRP6 promoter sequence
   Search SABiosciences Chromatin IP Primers for NLRP6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NLRP6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15

NLRP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NLRP6 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P000269:  view genomic region     (about GC identifiers)

Start:
278,365 bp from pter      End:
285,359 bp from pter
Size:
6,995 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NALP6_HUMAN, P59044 (See protein sequence)
Recommended Name: NACHT, LRR and PYD domains-containing protein 6  
Size: 892 amino acids; 98768 Da
Subunit: Binds to ASC with its DAPIN domain
Subcellular location: Cytoplasm. Cell membrane (By similarity). Nucleus membrane (By similarity)
Secondary accessions: A8K9F3

Explore the universe of human proteins at neXtProt for NLRP6: NX_P59044

Explore proteomics data for NLRP6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P59044

  • NLRP6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NLRP6 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001263629.1  NP_612202.2  

    ENSEMBL proteins: 
     ENSP00000433617   ENSP00000309767  

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    Cloud-Clone Corp. Proteins for NLRP6 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--
    GO:0031965nuclear membrane IEA--

    NLRP6 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for NLRP6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NLR: Nucleotide-binding domain and leucine rich repeat containing

    IUPHAR Guide to PHARMACOLOGY protein family classification: NLRP6 
    NOD-like receptor family

    4 InterPro protein domains:
     IPR011029 DEATH-like_dom
     IPR007111 NACHT_NTPase
     IPR027417 P-loop_NTPase
     IPR004020 DAPIN

    Graphical View of Domain Structure for InterPro Entry P59044

    ProtoNet protein and cluster: P59044

    3 Blocks protein domains:
    IPB000767 Disease resistance protein signature
    IPB003590 Leucine-rich repeat
    IPB004020 Pyrin domain


    UniProtKB/Swiss-Prot: NALP6_HUMAN, P59044
    Similarity: Belongs to the NLRP family
    Similarity: Contains 1 DAPIN domain
    Similarity: Contains 5 LRR (leucine-rich) repeats
    Similarity: Contains 1 NACHT domain


    NLRP6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NALP6_HUMAN, P59044
    Function: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose
    and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as
    an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow
    recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of
    colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful,
    inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote
    activation of NF-kappa-B and stimulate cAMP accumulation (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005000vasopressin receptor activity ISS--
    GO:0005524ATP binding IEA--
         
    NLRP6 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for NLRP6:
     Decreased Wnt reporter activit  Decreased number of cells in m  Decreased viability after Chla 

         11 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Nlrp6):
     behavior/neurological  cardiovascular system  cellular  digestive/alimentary  endocrine/exocrine gland 
     growth/size  hematopoietic system  homeostasis/metabolism  immune system  mortality/aging 
     tumorigenesis 

    NLRP6 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nlrp6tm1Macha for NLRP6

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NLRP6 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NLRP6

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050727regulation of inflammatory response ISS--

    NLRP6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NLRP6 (NALP6)

    Search CenterWatch for drugs/clinical trials and news about NLRP6 / NALP6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NLRP6 gene (2 alternative transcripts): 
    NM_001276700.1  NM_138329.2  

    Unigene Cluster for NLRP6:

    NLR family, pyrin domain containing 6
    Hs.352611  [show with all ESTs]
    Unigene Representative Sequence: AK292668
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000534750(uc010qvt.2) ENST00000312165(uc010qvs.2) ENST00000527946

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NLRP6

    Additional mRNA sequence: 

    AF479748.1 AK292668.1 AY154461.1 

    2 DOTS entries:

    DT.102835925  DT.120751126 

    10 AceView cDNA sequences:

    CD677002 AF479748 NM_138329 AI344276 AY154461 CD636368 CD636369 CD636374 
    CD636366 CD636372 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NLRP6 expression in normal human tissues (normalized intensities)      NLRP6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGACCTACC
    NLRP6 Expression
    About this image


    NLRP6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Thymus (Hematopoietic System)
             Thymus
     
     Blood (Hematopoietic System)
             neutrophils   

    See NLRP6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NLRP6

    SOURCE GeneReport for Unigene cluster: Hs.352611

    UniProtKB/Swiss-Prot: NALP6_HUMAN, P59044
    Tissue specificity: Highly expressed in granulocytes. Detected at much lower levels in T-cells

        SABiosciences Expression via Pathway-Focused PCR Array including NLRP6: 
              Inflammasomes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRP6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NLRP6 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nlrp61 , 5 NLR family, pyrin domain containing 61, 5 75.35(n)1
    72.81(a)1
      7 (86.14 cM)5
    1016131  NM_001081389.11  NP_001074858.11 
     1409209025 
    chicken
    (Gallus gallus)
    Aves NLRP66
    NLR family, pyrin domain containing 6
    29(a)
    1 ↔ 1
    5(47094-72756)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    28(a)
    26(a)
    1 ↔ many
    1 ↔ many
    2(147333628-147343185)
    GL343482.1(99797-117577)
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-66k16.26
    CABZ01044732.16
    (see all 6)
    Uncharacterized protein
    (see all 6)
    24(a)
    22(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    2(45509755-45512232)
    2(49295576-49298552)


    ENSEMBL Gene Tree for NLRP6 (if available)
    TreeFam Gene Tree for NLRP6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NLRP6 gene
    NLRP42  NLRP132  NLRP92  NLRC32  NLRP32  NLRP142  NLRP72  NLRP112  
    NLRP102  NLRP22  NLRP52  NLRP82  NLRP122  
    3 SIMAP similar genes for NLRP6 using alignment to 2 protein entries:     NALP6_HUMAN (see all proteins):
    MEFV    NLRP12    NLRP3

    NLRP6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/324 SNPs in NLRP6 are shown (see all 324)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1994757931,2
    Cuntested198864(+) CCCGCA/GGTGGG 1 -- int10--------
    rs1994757951,2
    Cuntested199103(+) ACGCCA/GTGGAC 2 M V mis10--------
    rs1994757961,2
    Cuntested199180(+) AAGAGA/GGCGGA 2 R syn10--------
    rs1994757991,2
    Cuntested199441(+) CACCCA/CAGTTT 1 -- int10--------
    rs1994758011,2
    Cuntested199938(+) CGGCGA/GCCGCT 2 R syn10--------
    rs1994758031,2
    Cuntested1100151(+) GTGCCG/ACAGAT 2 /P syn11Minor allele frequency- A:0.01EU 127
    rs1994758051,2
    Cuntested1100322(+) CTCCTC/GCTGGT 2 L syn10--------
    rs1994758071,2
    Cuntested1101021(+) GAGCGA/GATGCG 2 R syn10--------
    rs1994762261,2
    Cuntested1101419(+) GAAGA-/AGAGCCTG 1 S cds10--------
    rs1994758131,2
    Cuntested1101823(+) TCTGTC/TTGCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for NLRP6 (278365 - 285359 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for NLRP6 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv917n71CNV Loss21882294
    dgv914n71CNV Loss21882294
    dgv916n71CNV Loss21882294
    dgv915n71CNV Loss21882294
    esv32593CNV Loss17666407
    nsv896447CNV Loss21882294
    dgv913n71CNV Loss21882294
    nsv482153CNV Gain20164927
    nsv896440CNV Gain21882294
    dgv186n67CNV Gain20364138

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NLRP6
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609650    OMIM disorders: --

    4 diseases for NLRP6:    About MalaCards
    crohn's disease    hepatitis b    hepatitis    hypertension


    NLRP6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NLRP6
    Human Genome Epidemiology (HuGE) Navigator: NLRP6 (2 documents)

    Export disorders for NLRP6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NLRP6 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with NLRP6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NALPs: a novel protein family involved in inflammation. (PubMed id 12563287)1, 2, 3 Tschopp J....Burns K. (2003)
    2. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. (PubMed id 12019269)1, 2, 3 Wang L.... Bertin J. (2002)
    3. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. (PubMed id 12387869)1, 2, 9 Grenier J.M.... Bertin J. (2002)
    4. The genetics of NOD-like receptors in Crohn's disease . (PubMed id 20403135)1, 4 Cummings J.R....Jewell D.P. (2010)
    5. Aggregatibacter actinomycetemcomitans targets NLRP3 an d NLRP6 inflammasome expression in human mononuclear leukocytes. (PubMed id 22503597)1 Belibasakis G.N. and Johansson A. (2012)
    6. AVR/NAVR deficiency lowers blood pressure and differen tially affects urinary concentrating ability, cognition, and anxiety-like behavi or in male and female mice. (PubMed id 20923861)1 Herrera V.L....Ruiz-Opazo N. (2011)
    7. New gene functions in megakaryopoiesis and platelet fo rmation. (PubMed id 22139419)1 Gieger C....Soranzo N. (2011)
    8. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    9. Overlapping genes in Nalp6/PYPAF5 locus encode two V2-type vasopressin isoreceptors: angiotensin-vasopressin receptor (AVR) and non-AVR. (PubMed id 18413781)1 Herrera V.L....Ruiz-Opazo N. (2008)
    10. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 171389 HGNC: 22944 AceView: NALP6 Ensembl:ENSG00000174885 euGenes: HUgn171389
    ECgene: NLRP6 H-InvDB: NLRP6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for NLRP6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NLRP6 gene:
    Search GeneIP for patents involving NLRP6

    GeneCards and IP:
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