Aliases for NLRP5 Gene
External Ids for NLRP5 Gene
Previous HGNC Symbols for NLRP5 Gene
Previous GeneCards Identifiers for NLRP5 Gene
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for NLRP5 Gene
NLRP5 (NLR Family Pyrin Domain Containing 5) is a Protein Coding gene. Diseases associated with NLRP5 include Autoimmune Polyendocrine Syndrome and Autoimmune Polyendocrinopathy Syndrome , Type I, With Or Without Reversible Metaphyseal Dysplasia. An important paralog of this gene is NLRP14.
UniProtKB/Swiss-Prot for NLRP5 Gene
As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.