Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NLRP13 Gene

protein-coding   GIFtS: 49
GCID: GC19M056407

NLR Family, Pyrin Domain Containing 13

(Previous names: NACHT, leucine rich repeat and PYD containing 13)
(Previous symbol: NALP13)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
NLR Family, Pyrin Domain Containing 131 2     Nucleotide-Binding Oligomerization Domain1
NALP131 2 3 5     CLR19.72
NOD142 3 5     PAN132
NACHT, Leucine Rich Repeat And PYD Containing 131 2     NACHT, LRR And PYD Containing Protein 132
Nucleotide-Binding Oligomerization Domain Protein 142 3     NACHT, LRR And PYD Domains-Containing Protein 132
Leucine Rich Repeat And Pyrin Domain Containing 131     Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin
Domain Containing 132

External Ids:    HGNC: 229371   Entrez Gene: 1262042   Ensembl: ENSG000001735727   OMIM: 6096605   UniProtKB: Q86W253   

Export aliases for NLRP13 gene to outside databases

Previous GC identifers: GC19M061100 GC19M052718


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for NLRP13 Gene:
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short
NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a
NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM
606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment
domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via
their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed
12563287)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NLRP13 Gene:
NLRP13 (NLR family, pyrin domain containing 13) is a protein-coding gene. Diseases associated with NLRP13 include smallpox, and crohn's disease. An important paralog of this gene is NLRP4.

UniProtKB/Swiss-Prot: NAL13_HUMAN, Q86W25
Function: Involved in inflammation (Potential)

Gene Wiki entry for NLRP13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NLRP13
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNLRP13 promoter sequence
   Search Chromatin IP Primers for NLRP13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NLRP13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.43   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

NLRP13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NLRP13 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M056407:  view genomic region     (about GC identifiers)

Start:
56,403,065 bp from pter      End:
56,443,702 bp from pter
Size:
40,638 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NAL13_HUMAN, Q86W25 (See protein sequence)
Recommended Name: NACHT, LRR and PYD domains-containing protein 13  
Size: 1043 amino acids; 118884 Da
Secondary accessions: Q7RTR5

Explore the universe of human proteins at neXtProt for NLRP13: NX_Q86W25

Explore proteomics data for NLRP13 at MOPED


See NLRP13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_789780.2  
ENSEMBL proteins: 
 ENSP00000467899   ENSP00000343891  

NLRP13 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom MassSpec
OriGene Custom Protein Services for NLRP13
GenScript Custom Purified and Recombinant Proteins Services for NLRP13
Novus Biologicals NLRP13 Proteins
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for NLRP13

NLRP13 Antibody Products:

EMD Millipore Mono- and Polyclonal Antibodies for the study of NLRP13
Browse R&D Systems for Antibodies
OriGene Antibodies for NLRP13
OriGene Custom Antibody Services for NLRP13
Novus Biologicals NLRP13 Antibody
Search for Antibodies for NLRP13 at Abcam
Cloud-Clone Corp. Antibodies for NLRP13
ThermoFisher Antibodies for NLRP13
LSBio Antibodies in human, mouse, rat for NLRP13

NLRP13 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for NLRP13
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for NLRP13
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for NLRP13
Cloud-Clone Corp. CLIAs for NLRP13


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
NLR: Nucleotide-binding domain and leucine rich repeat containing

IUPHAR Guide to PHARMACOLOGY protein family classification: NLRP13
NOD-like receptor family

4 InterPro protein domains:
 IPR007111 NACHT_NTPase
 IPR027417 P-loop_NTPase
 IPR004020 DAPIN
 IPR011029 DEATH-like_dom

Graphical View of Domain Structure for InterPro Entry Q86W25

ProtoNet protein and cluster: Q86W25

1 Blocks protein domain: IPB004020 Pyrin domain

UniProtKB/Swiss-Prot: NAL13_HUMAN, Q86W25
Similarity: Belongs to the NLRP family
Similarity: Contains 1 DAPIN domain
Similarity: Contains 7 LRR (leucine-rich) repeats
Similarity: Contains 1 NACHT domain


NLRP13 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: NAL13_HUMAN, Q86W25
Function: Involved in inflammation (Potential)

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005524ATP binding IEA--
     
NLRP13 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NLRP13
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NLRP13

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NLRP13
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NLRP13

miRNA
Products:
    
miRTarBase miRNAs that target NLRP13:
hsa-mir-335-5p (MIRT017632)

Block miRNA regulation of human, mouse, rat NLRP13 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate NLRP13
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for NLRP13
Predesigned siRNA for gene silencing in human, mouse, rat NLRP13

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for NLRP13

Clone
Products:
     
OriGene clones in human, mouse for NLRP13 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NLRP13 (NM_176810)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NLRP13
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NLRP13

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for NLRP13
Browse ESI BIO Cell Lines and PureStem Progenitors for NLRP13 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRP13


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
nucleus2
peroxisome1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NLRP13
Interactions:

    Search GeneGlobe Interaction Network for NLRP13

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NLRP13 (NAL13)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for NLRP13 gene: 
NM_176810.2  

Unigene Cluster for NLRP13:

NLR family, pyrin domain containing 13
Hs.446924
Unigene Representative Sequence: NM_176810
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000588751 ENST00000342929(uc010ygg.2)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat NLRP13 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate NLRP13
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for NLRP13
Predesigned siRNA for gene silencing in human, mouse, rat NLRP13
Clone
Products:
     
OriGene clones in human, mouse for NLRP13 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NLRP13 (NM_176810)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NLRP13
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NLRP13
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for NLRP13
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NLRP13
  QuantiTect SYBR Green Assays in human, mouse, rat NLRP13
  QuantiFast Probe-based Assays in human, mouse, rat NLRP13

Additional mRNA sequence: AY154468.1 

1 DOTS entry:

DT.100737521 

4 AceView cDNA sequences:

BK001108 NM_176810 AY154468 BV182993 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

NLRP13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CAGGCTGCAG
NLRP13 Expression
About this image


NLRP13 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 2) fully expand
 
 Ovary (Reproductive System)
         Secondary Oocyte Antral Follicle
 
 Gonad
         Secondary Oocyte Antral Follicle
NLRP13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NLRP13 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.446924
    Custom PCR Arrays for NLRP13
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for NLRP13
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NLRP13
QuantiTect SYBR Green Assays in human, mouse, rat NLRP13
QuantiFast Probe-based Assays in human, mouse, rat NLRP13
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRP13

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for NLRP13 gene from Selected species (see all 5)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
dog
(Canis familiaris)
Mammalia NLRP131 NLR family, pyrin domain containing 13 74.8(n)
61.58(a)
  484287  XM_541402.3  XP_541402.3 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
29(a)
1 → many
GL343482.1(99797-117577)


ENSEMBL Gene Tree for NLRP13 (if available)
TreeFam Gene Tree for NLRP13 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for NLRP13 gene
NLRP42  NLRP92  NLRC32  NLRP62  NLRP32  NLRP142  NLRP72  NLRP112  
NLRP102  NLRP22  NLRP52  NLRP82  NLRP122  
11 SIMAP similar genes for NLRP13 using alignment to 1 protein entry:     NAL13_HUMAN:
CIAS1    NLRP14    NLRP3    NLRP12    NLRP11    NLRP2
NLRP5    NLRP9    NLRP4    NLRP8    NLRP7

NLRP13 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for NLRP13 (see all 1323)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1994758781,2
Cuntested156407485(-) CCTAGA/GTTGGC 2 G syn10--------
rs1994762591,2
Cuntested156413578(-) TTCACA/CCTGCA 1 -- int10--------
rs1994762551,2
Cuntested156421895(-) AGATAA/C/TCCTAG 1 -- int10--------
rs1994762541,2
Cuntested156422307(-) CAGACA/GGGGCT 1 -- int10--------
rs1994758751,2
Cuntested156423653(-) GAAGTA/GCCTTT 2 V syn10--------
rs1994762511,2
Cuntested156435533(-) CTAGCA/GTGGGC 1 -- int10--------
rs1994762491,2
Cuntested156443314(-) TACTCC/TTGAGG 1 -- int10--------
rs72546601,2
C,A--56406811(+) TGAGAC/TGCCGA 1 -- ds50010--------
rs1180362551,2
C,F--56406878(+) ACCCCC/AATCTC 1 -- ds50011Minor allele frequency- A:0.02NA 120
rs1132551191,2
F--56407057(+) AAAGGT/AGAAAG 1 -- ds50011Minor allele frequency- A:0.50CSA 2

HapMap Linkage Disequilibrium report for NLRP13 (56403065 - 56443702 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for NLRP13:    About this table    
Variant IDTypeSubtypePubMed ID
nsv912507CNV Gain21882294
nsv912508CNV Gain21882294
nsv510927CNV Complex20534489

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing NLRP13
DNA2.0 Custom Variant and Variant Library Synthesis for NLRP13

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 609660    OMIM disorders: --

5 diseases for NLRP13:    
About MalaCards
smallpox    crohn's disease    chronic lymphocytic leukemia    type 1 diabetes
leukemia


NLRP13 for disorders           About GeneDecksing

Genetic Association Database (GAD): NLRP13
Human Genome Epidemiology (HuGE) Navigator: NLRP13 (2 documents)

Export disorders for NLRP13 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for NLRP13 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NLRP13)
    Utopia: connect your pdf to the dynamic
world of online information

  1. NALPs: a novel protein family involved in inflammation. (PubMed id 12563287)1, 2, 3 Tschopp J.... Burns K. (Nat. Rev. Mol. Cell Biol. 2003)
  2. The genetics of NOD-like receptors in Crohn's disease. (PubMed id 20403135)1, 4 Cummings J.R....Jewell D.P. (Tissue Antigens 2010)
  3. Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885)1, 4 Enjuanes A....Campo E. (Cancer Res. 2008)
  4. NODs: intracellular proteins involved in inflammation and apoptosis. (PubMed id 12766759)1, 2 Inohara N. and Nunez G. (Nat. Rev. Immunol. 2003)
  5. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (Hum. Genet. 2012)
  6. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PubMed id 19875614)4 Paterson A.D....Bull S.B. (Diabetes 2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 126204 HGNC: 22937 AceView: NALP13 Ensembl:ENSG00000173572 euGenes: HUgn126204
ECgene: NLRP13 H-InvDB: NLRP13

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for NLRP13 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for NLRP13 gene:
Search GeneIP for patents involving NLRP13

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 Browse Kits and Assays available from EMD Millipore
 Browse Purified and Recombinant Proteins at EMD Millipore
 Browse Small Molecules at EMD Millipore
 EMD Millipore Mono- and Polyclonal Antibodies for the study of NLRP13
 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for NLRP13   OriGene RNAi products in human, mouse, rat for NLRP13  
 Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for NLRP13  
 OriGene qSTAR qPCR primer pairs in human, mouse for NLRP13   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for NLRP13   OriGene Custom Protein Services for NLRP13  

 
 
 Block miRNA regulation of human, mouse, rat NLRP13 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NLRP13
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NLRP13 Predesigned siRNA for gene silencing in human, mouse, rat NLRP13
 QuantiFast Probe-based Assays in human, mouse, rat NLRP13 QuantiTect SYBR Green Assays in human, mouse, rat NLRP13
 Custom PCR Arrays for NLRP13 Search Chromatin IP Primers for NLRP13
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NLRP13  Search GeneGlobe Interaction Network for NLRP13
 Search Regulatory tfbs for NLRP13
 GenScript Custom Purified and Recombinant Proteins Services for NLRP13 GenScript cDNA clones with any tag delivered in your preferred vector for NLRP13
 GenScript Custom Assay Services for NLRP13 GenScript Custom overexpressing Cell Line Services for NLRP13
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for NLRP13 (NAL13)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 NLRP13 antibodies
 NLRP13 proteins
 Search for Antibodies for NLRP13 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for NLRP13
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for NLRP13
 Antibodies for NLRP13
 ELISAs for NLRP13
 CLIAs for NLRP13



 Browse ESI BIO Cell Lines and PureStem Progenitors for NLRP13
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NLRP13
 Browse SwitchGear 3'UTR luciferase reporter plasmids for NLRP13
 SwitchGear Promoter luciferase reporter plasmids for NLRP13
 ThermoFisher Antibodies for NLRP13
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NLRP13
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NLRP13
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NLRP13
 LSBio Antibodies in human, mouse, rat for NLRP13
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      NLRP13 gene at Home site.
Version: 3.12.166 28 Aug 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4