Aliases for NLGN4X Gene
External Ids for NLGN4X Gene
Previous HGNC Symbols for NLGN4X Gene
Previous GeneCards Identifiers for NLGN4X Gene
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for NLGN4X Gene
NLGN4X (Neuroligin 4, X-Linked) is a Protein Coding gene. Diseases associated with NLGN4X include Autism Susceptibility, X-Linked 2 and Asperger Syndrome Susceptibility, X-Linked 2. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. GO annotations related to this gene include protein homodimerization activity and receptor activity. An important paralog of this gene is NLGN4Y.
UniProtKB/Swiss-Prot for NLGN4X Gene
Putative neuronal cell surface protein involved in cell-cell-interactions.