Aliases for NLGN4X Gene
External Ids for NLGN4X Gene
Previous HGNC Symbols for NLGN4X Gene
Previous GeneCards Identifiers for NLGN4X Gene
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for NLGN4X Gene
NLGN4X (Neuroligin 4, X-Linked) is a Protein Coding gene. Diseases associated with NLGN4X include Autism X-Linked 2 and Asperger Syndrome, X-Linked 2. Among its related pathways are Transmission across Chemical Synapses and Protein-protein interactions at synapses. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and receptor activity. An important paralog of this gene is NLGN4Y.
UniProtKB/Swiss-Prot for NLGN4X Gene
Putative neuronal cell surface protein involved in cell-cell-interactions.