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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NKX6-2 Gene

protein-coding   GIFtS: 45
GCID: GC10M134598

NK6 homeobox 2

(Previous names: NK6 transcription factor related, locus 2 (Drosophila)...)
 Explore 5 diseases affiliated with
NKX6-2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NKX6-2    

Aliases
for NKX6-2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
NK6 Homeobox 21 2     NK6 Transcription Factor Related, Locus 2 (Drosophila)1
NKX6B1 2 3 5     Glial And Testis-Specific Homeobox Protein2
GTX1 2 3     Homeobox 6B2
Homeobox Protein NK-6 Homolog B2 3     Homeobox Protein Nkx-6.22
NKX6.22 5     NK Homeobox Family 6, B2
NKX6.11     NK6 Transcription Factor Related, Locus 22

External Ids:    HGNC: 193211   Entrez Gene: 845042   Ensembl: ENSG000001488267   OMIM: 6059555   UniProtKB: Q9C0563   

Export aliases for NKX6-2 gene to outside databases

Previous GC identifers: GC10U990123 GC10M134475 GC10M134032 GC10M134448 GC10M128149


Summaries
for NKX6-2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Gene Wiki entry for NKX6-2


Genomic Views
for NKX6-2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_008818.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NKX6-2 gene promoter:
         STAT1   Pax-6   STAT1beta   STAT1alpha   MEF-2A   POU2F1   POU2F1a   Sox9   SEF-1 (1)   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NKX6-2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NKX6-2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NKX6-2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26   Ensembl cytogenetic band:  10q26.3   HGNC cytogenetic band: 10q26.3

NKX6-2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NKX6-2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M134598:  view genomic region     (about GC identifiers)

Start:
 134,598,297 bp from pter      End:
 134,599,556 bp from pter
Size:
 1,260 bases      Orientation:
 minus strand

Proteins
for NKX6-2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NKX62_HUMAN, Q9C056 (See protein sequence)
Recommended Name: Homeobox protein Nkx-6.2  
Size: 277 amino acids; 29263 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q5JSF3

Explore the universe of human proteins at neXtProt for NKX6-2: NX_Q9C056

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C056

    • NKX6-2 Protein expression data from MOPED and PaxDb:    About this image 
    NKX6-2 Protein Expression
    REFSEQ proteins: NP_796374.1  
    ENSEMBL proteins: 
     ENSP00000357581  

    Human Recombinant Protein Products for NKX6-2: 
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    OriGene Custom Protein Services for NKX6-2 
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    Novus Biologicals NKX6-2 Protein
    Novus Biologicals NKX6-2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NKX6-2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS11210186

    NKX6-2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NKX6-2

    Protein Domains /
    Families
    for NKX6-2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NKX6-2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR000047 HTH_motif
     IPR017970 Homeobox_CS
     IPR020479 Homeobox_metazoa
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9C056

    ProtoNet protein and cluster: Q9C056

    1 Blocks protein family: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: NKX62_HUMAN, Q9C056
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for NKX6-2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000976transcription regulatory region sequence-specific DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS11210186
    GO:0043565sequence-specific DNA binding ----
         
    NKX6-2 for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Nkx6-2):
     behavior/neurological  cellular  mortality/aging  nervous system  normal 
     renal/urinary system  vision/eye 

    NKX6-2 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Nkx6-2Nkx6-tm1Qiu for NKX6-2
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for NKX6-2 

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NKX6-2
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NKX6-2:
    hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmid: NKX6-2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NKX6-2
    OriGene shRNA RFP: NKX6-2
    OriGene siRNA: NKX6-2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NKX6-2
    Sirion Biotech Custom design and validation of potent shRNA sequences against NKX6-2 

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NKX6-2
    Sirion Biotech Customized adenovirus for overexpression of NKX6-2 
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NKX6-2
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    Cell Line
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    Sirion Biotech Customized stable overexpressing cell line services for NKX6-2
    Sirion Biotech Customized inducible overexpressing cell line services for NKX6-2

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for NKX6-2


    Pathways & Interactions
    for NKX6-2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NKX6-2

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS11210186
    GO:0010454negative regulation of cell fate commitment IEA--
    GO:0010455positive regulation of cell fate commitment IEA--
    GO:0021912regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification IEA--

    NKX6-2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NKX6-2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NKX6-2
    Search CenterWatch for drugs/clinical trials and news about NKX6-2 / NKX62 

    Transcripts
    for NKX6-2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NKX6-2 gene: 
    NM_177400.2  

    Unigene Cluster for NKX6-2:

    NK6 homeobox 2
    Hs.134013  [show with all ESTs]
    Unigene Representative Sequence: NM_177400
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000368592(uc001llr.2)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NKX6-2
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NKX6-2:
    hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmid: NKX6-2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NKX6-2
    OriGene shRNA RFP: NKX6-2
    OriGene siRNA: NKX6-2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NKX6-2
    Sirion Biotech Custom design and validation of potent shRNA sequences against NKX6-2 
    Clone
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    GenScript: all cDNA clones in your preferred vector: NKX6-2 (NM_177400)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NKX6-2 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NKX6-2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NKX6-2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NKX6-2

    Additional cDNA sequence: 

    BC101635.1 BC104823.1 

    1 DOTS entry:

    DT.75147528 

    2 AceView cDNA sequences:

    NM_177400 AI870533 

    GeneLoc Exon Structure


    Expression
    for NKX6-2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NKX6-2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCGAGAGCC
    NKX6-2 Expression
    About this image

    NKX6-2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PancreasIslets of LangerhansAlpha CellsPancreas
    PancreasPancreatic AciniAcinar CellsPancreas
    PancreasPrepancreatic Dorsal Foregut EndodermPre-Pancreatic Foregut Endoderm CellsPancreas
    PancreasPrepancreatic Ventral Foregut EndodermPre-Pancreatic Foregut Endoderm CellsPancreas
    BrainHypothalamusBrain
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    Blimp1- mVenus and stella-ECFP genetically modified stem cells (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    N2/LSB/S/F8-induced cells (Generation of midbra...)
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

    See NKX6-2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NKX6-2

    SOURCE GeneReport for Unigene cluster: Hs.134013

    UniProtKB/Swiss-Prot: NKX62_HUMAN, Q9C056
    Tissue specificity: Highest expression in brain

        SABiosciences Custom PCR Arrays for NKX6-2
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for NKX6-2

    Orthologs
    for NKX6-2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NKX6-2 gene from 5/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nkx6-21 , 5 NK6 homeobox 21, 5 88.57(n)1
    97.11(a)1    		   7 (84.57 cM)5
    149121  NM_183248.31  NP_899071.21 
     1395793775 
    chicken
    (Gallus gallus)    		 Aves NKX6-21 NK6 homeobox 2 82.52(n)
    88.68(a)    		   395591  NM_001199548.1  NP_001186477.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NKX6-26
    		 --
    		 72(a)
    		 1 ↔ 1
    		 5(43836459-43836674)
    zebrafish
    (Danio rerio)    		 Actinopterygii nkx6.21 NK6 transcription factor related, locus 2 74.35(n)
    79.93(a)    		   565782  NM_001135784.2  NP_001129256.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta HGTX1 CG13475-PA 59.55(n)
    58.64(a)    		   53446  NM_144357.2  NP_652614.1 


    ENSEMBL Gene Tree for NKX6-2 (if available)
    TreeFam Gene Tree for NKX6-2 (if available) 

    Paralogs
    for NKX6-2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NKX6-2 gene
    NOTO2  NKX6-32  EMX22  NKX6-12  EMX12  
    2 SIMAP similar genes for NKX6-2 using alignment to 1 protein entry:     NKX62_HUMAN:
    NKX6-3    NKX6-1

    NKX6-2 for paralogs           About GeneDecksing



    Genomic Variants
    for NKX6-2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/35 NCBI SNPs in NKX6-2 are shown (see all 35)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs28040041,2
    		C,F,A,H--134597898(-) CCGCTC/TGGCCG 1 -- ds500116Minor allele frequency- T:0.25NS NA WA EA 1830
    rs1437232891,2
    		--134598046(+) CGAGGC/TGAGGC 1 -- ds50010--------
    rs2019234711,2
    		--134598443(+) GCCGCC/GGCCGC 2 R G mis10--------
    rs2015440411,2
    		--134598645(+) TTGCGA/CCACTT 2 W C mis10--------
    rs1481019981,2
    		C--134598709(+) GCGGGA/GCCCGG 1 -- int10--------
    rs2008791591,2
    		--134598997(+) GGCGGA/GGTCCC 1 -- int10--------
    rs1995133961,2
    		--134599339(+) AAGCCC/GGCCGG 2 A syn10--------
    rs2014258671,2
    		C,F--134599389(+) GGCCAT/GGTTGT 2 /M /L mis11Minor allele frequency- G:0.01EU 541
    rs1851953391,2
    		--134599855(+) TCCCCA/GGGGAC 1 -- us2k10--------
    rs27373981,2
    		C,F,H--134599872(-) CAAGCG/TGGATT 1 -- us2k115Minor allele frequency- T:0.12NS NA CSA WA 1715

    HapMap Linkage Disequilibrium report for NKX6-2 (134598297 - 134599556 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for NKX6-2
         3 CNVs: 4718 4719 29874
         1 Indel: 11031

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NKX6-2
    DNA2.0 Custom Variant and Variant Library Synthesis for NKX6-2

    Disorders / Diseases
    for NKX6-2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NKX6-2 for disorders           About GeneDecksing

    OMIM gene information: 605955    OMIM disorders: --

    5 diseases for NKX6-2:    About MalaCards
    chronic myocardial ischemia    neutropenia    hermaphroditism    ischemia
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for NKX6-2:
    Neutropenia

    Export disorders for NKX6-2 gene to outside databases

    Publications
    for NKX6-2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NKX6-2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with NKX6-2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, expression and chromosomal location of NKX6B to 10q26, a region frequently deleted in brain tumors. (PubMed id 11210186)1, 2, 3, 9 Lee S.-H.... Belouchi A. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    5. Gtx, an oligodendrocyte-specific homeodomain protein, has repressor activity. (PubMed id 10931524)9 Awatramani R....Kamholz J. (2000)
    6. Antisense masking reveals contributions of mRNA-rRNA base pairing to translation of Gtx and FGF2 mRNAs. (PubMed id 18832380)9 Panopoulos P. and Mauro V.P. (2008)
    7. Co-localization of Nkx6.2 and Nkx2.2 homeodomain prot eins in differentiated myelinating oligodendrocytes. (PubMed id 19780200)9 Cai J....Qiu M. (2010)
    8. Regulation of myelin development. (PubMed id 9050362)9 Kamholz J.A. (1996)
    9. The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain. (PubMed id 14754886)9 Hashimoto Y....Nishimoto I. (2004)
    10. Development of a gene-trap vector with a highly sensitive fluorescent protein reporter system for expression profiling. (PubMed id 18615730)9 Tanaka T.S....Stanford W.L. (2008)

    External Searches for NKX6-2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing NKX6-2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84504 HGNC: 19321 AceView: NKX6-2 Ensembl:ENSG00000148826 euGenes: HUgn84504
    ECgene: NKX6-2 H-InvDB: NKX6-2

    Other Databases showing NKX6-2 gene

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    Specialized Databases showing NKX6-2 gene

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    PharmGKB entry for NKX6-2 Pharmacogenomics, SNPs, Pathways

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