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Aliasesfor NKX2-1-AS1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Subcategory (RNA class): antisenseQuality score for this RNA gene is 3 Aliases NKX2-1 Antisense RNA 1 1 2 NKX2-1 Antisense RNA 1 (Non-Protein Coding)1
External Ids: HGNC: 40585 1 Entrez Gene: 100506237 2 Ensembl: ENSG00000253563 7 Export aliases for NKX2-1-AS1 gene to outside databases
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Summariesfor NKX2-1-AS1 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus GeneCards Summary for NKX2-1-AS1 Gene: NKX2-1-AS1 (NKX2-1 antisense RNA 1) is an RNA gene, and is affiliated with the antisense RNA class.
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Genomic Viewsfor NKX2-1-AS1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus RefSeq DNA sequence at NCBI GenBank: NC_000014.8 NC_018925.2 NT_026437.13 Regulatory elements: Search for regulatory transcription factor binding sites for NKX2-1-AS1 Other transcription factors Search Chromatin IP Primers for NKX2-1-AS1 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NKX2-1-AS1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Ensembl cytogenetic band: 14q13.3 HGNC cytogenetic band: 14q13.3 NKX2-1-AS1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P036989: view genomic region
(about GC identifiers )
Start: 36,988,483 bp from pter End:
36,992,221 bp from pter
Size: 3,739 bases Orientation:
plus strand
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Proteinsfor NKX2-1-AS1 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec ,
Cloud-Clone Corp. ,
eBioscience , and/or
antibodies-online ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences ,
Cloud-Clone Corp. ,
eBioscience , and/or
antibodies-online ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam ,
Cloud-Clone Corp ,
antibodies-online ,
and/or others.)
About This Section GeneCards Plus UniProtKB: --
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Domains /for NKX2-1-AS1 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: LNCRNA: Long non-coding RNAs
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Functionfor NKX2-1-AS1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
Vector BioLabs
and/or Addgene ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Flow cytometry from eBioscience ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus
Animal Models: Cell Line GenScript Custom overexpressing Cell Line Services for NKX2-1-AS1 Browse ESI BIO Cell Lines and PureStem Progenitors for NKX2-1-AS1 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1
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Localizationfor NKX2-1-AS1 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus
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Pathways & Interactionsfor NKX2-1-AS1 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus
Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NKX2-1-AS1 Interactions: Search GeneGlobe Interaction Network for NKX2-1-AS1
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Drugs & Compoundsfor NKX2-1-AS1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus
Browse compounds at ApexBio Browse Tocris compounds for NKX2-1-AS1
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Transcriptsfor NKX2-1-AS1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
and/or Addgene ,
Primers from
OriGene , and/or
QIAGEN ,
Flow cytometry from eBioscience
)About This Section GeneCards Plus Unigene Cluster for NKX2-1-AS1:
NKX2-1 antisense RNA 1 Hs.497090 [show with all ESTs ] Unigene Representative Sequence: XR_132759 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000521292(antisense) Additional mRNA sequence: BX161496.1 XR_132759.1 XR_172038.1
2 DOTS entries : DT.100749639 DT.97792573 GeneLoc Exon Structure
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Expression for NKX2-1-AS1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus
Expression evidence for NKX2-1-AS1:none
NKX2-1-AS1 expression in normal human tissues
(normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
NKX2-1-AS1 Protein expression data from MOPED1 2 3 : SOURCE GeneReport for Unigene cluster: Hs.497090 Custom PCR Arrays for NKX2-1-AS1 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat NKX2-1-AS1 Search QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 Search QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1
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Orthologsfor NKX2-1-AS1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus
ENSEMBL Gene Tree for NKX2-1-AS1 (if available)TreeFam Gene Tree for NKX2-1-AS1 (if available)
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Paralogsfor NKX2-1-AS1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus
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Genomic Variantsfor NKX2-1-AS1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 14 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for NKX2-1-AS1 (36988483 - 36992221 bp)
Structural Variations Database of Genomic Variants (DGV) variations for NKX2-1-AS1: -- Site Specific Mutation Identification with PCR Assays
2 Copy Number PCR Panels containing NKX2-1-AS1 :
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Disorders
/ Diseasesfor NKX2-1-AS1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus
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Publicationsfor NKX2-1-AS1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed articles for NKX2-1-AS1 gene integrated from 10 sources :(articles sorted by number of sources associating them with NKX2-1-AS1) Utopia : connect your pdf to the dynamic
Genome wide association study of age at menarche in the Japanese population. (PubMed id 23667675) 1 (PLoS ONE 2013) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 (Genome Res. 2006)
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External Searches for NKX2-1-AS1 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing NKX2-1-AS1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing NKX2-1-AS1 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing NKX2-1-AS1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
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About This Section GeneCards Plus Patent Information for NKX2-1-AS1 gene: NKX2-1-AS1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor NKX2-1-AS1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , eBioscience , antibodies-online , and/or others, Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Addgene , Cell lines from GenScript , and ESI BIO , Flow cytometery from eBioscience , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat NKX2-1-AS1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NKX2-1-AS1 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NKX2-1-AS1 Predesigned siRNA for gene silencing in human mouse rat Search QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 Search QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 Custom PCR Arrays for NKX2-1-AS1 Search Chromatin IP Primers for NKX2-1-AS1 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NKX2-1-AS1 Search GeneGlobe Interaction Network for NKX2-1-AS1 Search Regulatory tfbs for NKX2-1-AS1
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NKX2-1-AS1
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