Aliases
for NKX2-1-AS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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Subcategory (RNA class): antisense
Quality score for this RNA gene is 3
| Aliases |
|---|
| NKX2-1 Antisense RNA 11 2 | | NKX2-1 Antisense RNA 1 (Non-Protein Coding)1 |
| External Ids: | HGNC: 405851 | Entrez Gene: 1005062372 | Ensembl: ENSG000002535637 |
Export aliases for NKX2-1-AS1 gene to outside databases
|---|
Summaries
for NKX2-1-AS1 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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GeneCards Summary for NKX2-1-AS1 Gene:
NKX2-1-AS1 (NKX2-1 antisense RNA 1) is an RNA gene, and is affiliated with the antisense RNA class.
|
Genomic Views
for NKX2-1-AS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000014.9 NC_018925.2 NT_026437.13
Regulatory elements:
 Search for regulatory transcription factor binding sites for NKX2-1-AS1
Other transcription factors
Search Chromatin IP Primers for NKX2-1-AS1
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NKX2-1-AS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 14q13.3 HGNC cytogenetic band: 14q13.3NKX2-1-AS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P036989: view genomic region
(about GC identifiers)
Start:
|
36,988,483 bp from pter |
End:
|
36,992,221 bp from pter |
Size:
|
3,739 bases |
Orientation:
|
plus strand |
|
Proteins
for NKX2-1-AS1 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
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UniProtKB: --
|
Domains /
Families
for NKX2-1-AS1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | HGNC Gene Families:
LNCRNA: Long non-coding RNAs
-- |
Function
for NKX2-1-AS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for NKX2-1-AS1 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for NKX2-1-AS1  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
Localization
for NKX2-1-AS1 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for NKX2-1-AS1 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NKX2-1-AS1
Interactions:
Search GeneGlobe Interaction Network for NKX2-1-AS1
|
Drugs & Compounds
for NKX2-1-AS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
TryGeneCards Plus |  Browse compounds at ApexBio
 Browse Tocris compounds for NKX2-1-AS1
|
Transcripts
for NKX2-1-AS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
About This Section
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Unigene Cluster for NKX2-1-AS1: NKX2-1 antisense RNA 1 Hs.497090 [show with all ESTs]Unigene Representative Sequence: XR_1327591 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000521292(antisense)
Additional mRNA sequence: BX161496.1 XR_132759.1 XR_172038.1 2 DOTS entries: DT.100749639 DT.97792573
GeneLoc Exon Structure
|
Expression
for NKX2-1-AS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
TryGeneCards Plus | Expression evidence for NKX2-1-AS1:none
NKX2-1-AS1 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image NKX2-1-AS1 Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  --
SOURCE GeneReport for Unigene cluster: Hs.497090
Custom PCR Arrays for NKX2-1-AS1
Primer
Products: |  | Browse OriGene qPCR
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat NKX2-1-AS1 | | | Search QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 | | | Search QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
Orthologs
for NKX2-1-AS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
ENSEMBL Gene Tree for NKX2-1-AS1 (if available)
TreeFam Gene Tree for NKX2-1-AS1 (if available) |
Paralogs
for NKX2-1-AS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for NKX2-1-AS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NKX2-1-AS1 (36988483 - 36992221 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for NKX2-1-AS1: --
| | Site Specific Mutation Identification with PCR Assays |
| | 2 Copy Number PCR Panels containing NKX2-1-AS1: |
|
Disorders
/ Diseases
for NKX2-1-AS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
TryGeneCards Plus | -- |
Publications
for NKX2-1-AS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for NKX2-1-AS1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NKX2-1-AS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genome wide association study of age at menarche in the Japanese population. (PubMed id 23667675)1 Tanikawa C....Matsuda K. (PLoS ONE 2013)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
|
External Searches for NKX2-1-AS1 gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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|
Genome Databases showing NKX2-1-AS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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|
Other Databases showing NKX2-1-AS1 gene
(According to HUGE)
About This Section
TryGeneCards Plus | -- |
Specialized Databases showing NKX2-1-AS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
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|
About This Section
TryGeneCards Plus | Patent Information for NKX2-1-AS1 gene:
Search GeneIP for patents involving NKX2-1-AS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NKX2-1-AS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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 | |
 |
| | | | |
 |
 |
|  | Block miRNA regulation of human, mouse, rat NKX2-1-AS1 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing NKX2-1-AS1 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NKX2-1-AS1 | | Predesigned siRNA for gene silencing in human, mouse, rat NKX2-1-AS1 | | | Search QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 | | Search QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 | | | Custom PCR Arrays for NKX2-1-AS1 | | Search Chromatin IP Primers for NKX2-1-AS1 | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NKX2-1-AS1 | | Search GeneGlobe Interaction Network for NKX2-1-AS1 | | | Search Regulatory tfbs for NKX2-1-AS1 |
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 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
| |  |  |  |  | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NKX2-1-AS1 |
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