Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NKX2-1-AS1 Gene

Subcategory (RNA class) for NKX2-1-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for NKX2-1-AS1 Gene

  • NKX2-1 Antisense RNA 1 2 3 5
  • NKX2-1 Antisense RNA 1 (Non-Protein Coding) 2

External Ids for NKX2-1-AS1 Gene

Previous GeneCards Identifiers for NKX2-1-AS1 Gene

  • GC14P036989

Summaries for NKX2-1-AS1 Gene

GeneCards Summary for NKX2-1-AS1 Gene

NKX2-1-AS1 (NKX2-1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for NKX2-1-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NKX2-1-AS1 Gene

Genomics for NKX2-1-AS1 Gene

GeneHancer (GH) Regulatory Elements for NKX2-1-AS1 Gene

Promoters and enhancers for NKX2-1-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I036517 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE dbSUPER 550.8 0.0 -45 4.2 ELF3 PKNOX1 INSM2 DMAP1 GLI4 ZNF2 ZNF48 RAD21 RFX5 ZNF335 ENSG00000257520 NKX2-1 NKX2-1-AS1 PAX9 NKX2-8 SFTA3 ENSG00000283098
GH14I036676 Enhancer 0.7 Ensembl ENCODE dbSUPER 10 +157.1 157085 0.3 SP1 NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 PAX9 ENSG00000258690
GH14I036281 Enhancer 0.6 ENCODE 9.9 -237.8 -237768 0.2 HCFC1 NFYC SIX5 ELF1 GABPA ETS1 GABPB1 ZNF143 PRDM10 CREM SFTA3 NKX2-1-AS1 NKX2-1 RPL29P3 NKX2-8 MBIP RN7SKP21
GH14I036279 Enhancer 0.5 ENCODE 9.9 -239.5 -239504 1.1 POLR2A POU5F1 HMBOX1 NFE2 SFTA3 NKX2-1 NKX2-1-AS1 RPL29P3 NKX2-8 MBIP RN7SKP21
GH14I036673 Enhancer 0.2 dbSUPER 10 +154.3 154259 0.3 NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 PAX9 ENSG00000258690
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NKX2-1-AS1 Gene

Genomic Locations for NKX2-1-AS1 Gene
chr14:36,519,278-36,523,016
(GRCh38/hg38)
Size:
3,739 bases
Orientation:
Plus strand
chr14:36,988,483-36,992,221
(GRCh37/hg19)

Genomic View for NKX2-1-AS1 Gene

Genes around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NKX2-1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NKX2-1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NKX2-1-AS1 Gene

Proteins for NKX2-1-AS1 Gene

Post-translational modifications for NKX2-1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NKX2-1-AS1 Gene

Domains & Families for NKX2-1-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NKX2-1-AS1 Gene

Function for NKX2-1-AS1 Gene

Phenotypes From GWAS Catalog for NKX2-1-AS1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NKX2-1-AS1 Gene

Localization for NKX2-1-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NKX2-1-AS1 Gene

Pathways & Interactions for NKX2-1-AS1 Gene

SuperPathways for NKX2-1-AS1 Gene

No Data Available

Interacting Proteins for NKX2-1-AS1 Gene

Gene Ontology (GO) - Biological Process for NKX2-1-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NKX2-1-AS1 Gene

Drugs & Compounds for NKX2-1-AS1 Gene

No Compound Related Data Available

Transcripts for NKX2-1-AS1 Gene

mRNA/cDNA for NKX2-1-AS1 Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NKX2-1-AS1 Gene

NKX2-1 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NKX2-1-AS1 Gene

No ASD Table

Relevant External Links for NKX2-1-AS1 Gene

GeneLoc Exon Structure for
NKX2-1-AS1
ECgene alternative splicing isoforms for
NKX2-1-AS1

Expression for NKX2-1-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NKX2-1-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for NKX2-1-AS1 Gene

This gene is overexpressed in Thyroid (x33.0) and Lung (x11.2).

SOURCE GeneReport for Unigene cluster for NKX2-1-AS1 Gene:

Hs.497090
genes like me logo Genes that share expression patterns with NKX2-1-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NKX2-1-AS1 Gene

Orthologs for NKX2-1-AS1 Gene

Evolution for NKX2-1-AS1 Gene

ENSEMBL:
Gene Tree for NKX2-1-AS1 (if available)
TreeFam:
Gene Tree for NKX2-1-AS1 (if available)

No data available for Orthologs for NKX2-1-AS1 Gene

Paralogs for NKX2-1-AS1 Gene

No data available for Paralogs for NKX2-1-AS1 Gene

Variants for NKX2-1-AS1 Gene

Sequence variations from dbSNP and Humsavar for NKX2-1-AS1 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs137852692 pathogenic, Choreoathetosis, hypothyroidism, and neonatal respiratory distress 36,517,781(+) C/A upstream_transcript_variant
rs137852693 pathogenic, Choreoathetosis, hypothyroidism, and neonatal respiratory distress 36,517,871(+) C/A/G upstream_transcript_variant
rs137852694 pathogenic, Benign hereditary chorea 36,517,739(+) G/A upstream_transcript_variant
rs147542347 likely-benign, Benign hereditary chorea, Choreoathetosis, hypothyroidism, and neonatal respiratory distress 36,517,391(+) C/A upstream_transcript_variant
rs201979429 likely-benign, Benign hereditary chorea, Choreoathetosis, hypothyroidism, and neonatal respiratory distress 36,520,101(+) C/A/G/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for NKX2-1-AS1 Gene

Variant ID Type Subtype PubMed ID
esv23132 CNV loss 19812545
nsv564346 CNV loss 21841781

Additional Variant Information for NKX2-1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NKX2-1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NKX2-1-AS1 Gene

Disorders for NKX2-1-AS1 Gene

Additional Disease Information for NKX2-1-AS1

No disorders were found for NKX2-1-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NKX2-1-AS1 Gene

Publications for NKX2-1-AS1 Gene

  1. Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. (PMID: 25307233) Zhao W … Jiao S (Scientific reports 2014) 3 58
  2. Genome wide association study of age at menarche in the Japanese population. (PMID: 23667675) Tanikawa C … Matsuda K (PloS one 2013) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for NKX2-1-AS1 Gene

Sources for NKX2-1-AS1 Gene

Content
Loading form....