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Aliases for NKX2-1-AS1 Gene

Subcategory (RNA class) for NKX2-1-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for NKX2-1-AS1 Gene

  • NKX2-1 Antisense RNA 1 2 3 5
  • NKX2-1 Antisense RNA 1 (Non-Protein Coding) 2

External Ids for NKX2-1-AS1 Gene

Previous GeneCards Identifiers for NKX2-1-AS1 Gene

  • GC14P036989

Summaries for NKX2-1-AS1 Gene

GeneCards Summary for NKX2-1-AS1 Gene

NKX2-1-AS1 (NKX2-1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NKX2-1-AS1 Gene

Genomics for NKX2-1-AS1 Gene

Regulatory Elements for NKX2-1-AS1 Gene

Enhancers for NKX2-1-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F036676 1.1 Ensembl ENCODE 10 +157.1 157103 0.4 ZNF493 INSM2 FEZF1 ZNF2 ZNF155 ZEB1 ZNF335 ZNF121 ZNF23 ZNF366 NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 ENSG00000258690
GH14F036279 0.8 Ensembl ENCODE 9.9 -239.5 -239505 1.1 CTBP1 GATA3 PKNOX1 HMBOX1 POU5F1 NFE2 SFTA3 NKX2-1-AS1 NKX2-1 RPL29P3 NKX2-8 MBIP RN7SKP21
GH14F036281 0.7 ENCODE 9.9 -237.8 -237769 0.2 ATF1 L3MBTL2 HCFC1 NFYC SIX5 MNT ETS1 NFYB GABPB1 ZNF143 SFTA3 NKX2-1 NKX2-1-AS1 RPL29P3 NKX2-8 MBIP RN7SKP21
GH14F036517 1.2 Ensembl ENCODE 0.8 0.0 -45 4.2 ELF3 PKNOX1 INSM2 GLI4 DMAP1 ZNF48 RAD21 ZNF2 GLIS2 ZNF366 PAX9 NKX2-8 NKX2-1-AS1 SFTA3
GH14F036514 0.9 FANTOM5 ENCODE 0.8 -4.4 -4430 0.6 RNF2 SUZ12 CBX2 CTBP2 EZH2 SFTA3 NKX2-1 MBIP NKX2-1-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for NKX2-1-AS1 Gene

Chromosome:
14
Start:
36,519,278 bp from pter
End:
36,523,016 bp from pter
Size:
3,739 bases
Orientation:
Plus strand

Genomic View for NKX2-1-AS1 Gene

Genes around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NKX2-1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NKX2-1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NKX2-1-AS1 Gene

Proteins for NKX2-1-AS1 Gene

Post-translational modifications for NKX2-1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NKX2-1-AS1 Gene

Domains & Families for NKX2-1-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NKX2-1-AS1 Gene

Function for NKX2-1-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NKX2-1-AS1 Gene

Localization for NKX2-1-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NKX2-1-AS1 Gene

Pathways & Interactions for NKX2-1-AS1 Gene

SuperPathways for NKX2-1-AS1 Gene

No Data Available

Interacting Proteins for NKX2-1-AS1 Gene

Gene Ontology (GO) - Biological Process for NKX2-1-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NKX2-1-AS1 Gene

Transcripts for NKX2-1-AS1 Gene

mRNA/cDNA for NKX2-1-AS1 Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NKX2-1-AS1 Gene

NKX2-1 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NKX2-1-AS1 Gene

No ASD Table

Relevant External Links for NKX2-1-AS1 Gene

GeneLoc Exon Structure for
NKX2-1-AS1
ECgene alternative splicing isoforms for
NKX2-1-AS1

Expression for NKX2-1-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NKX2-1-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for NKX2-1-AS1 Gene

This gene is overexpressed in Thyroid (x33.0) and Lung (x11.2).

SOURCE GeneReport for Unigene cluster for NKX2-1-AS1 Gene:

Hs.497090
genes like me logo Genes that share expression patterns with NKX2-1-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for NKX2-1-AS1 Gene

Orthologs for NKX2-1-AS1 Gene

Evolution for NKX2-1-AS1 Gene

ENSEMBL:
Gene Tree for NKX2-1-AS1 (if available)
TreeFam:
Gene Tree for NKX2-1-AS1 (if available)

No data available for Orthologs for NKX2-1-AS1 Gene

Paralogs for NKX2-1-AS1 Gene

No data available for Paralogs for NKX2-1-AS1 Gene

Variants for NKX2-1-AS1 Gene

Sequence variations from dbSNP and Humsavar for NKX2-1-AS1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs137852692 Pathogenic 36,517,781(-) CGCAG(G/T)TCAAG upstream-variant-2KB, reference, missense
rs137852693 Pathogenic 36,517,871(-) TGTAC(C/G/T)AGCTG upstream-variant-2KB, reference, missense, stop-gained
rs137852694 Pathogenic 36,517,739(-) AGCGC(C/T)AGGCC upstream-variant-2KB, reference, stop-gained
rs28936671 Pathogenic 36,517,757(-) ACCAC(A/C)GCTAC upstream-variant-2KB, reference, missense
rs28936672 Pathogenic 36,517,771(-) GATCT(G/T)GTTCC upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for NKX2-1-AS1 Gene

Variant ID Type Subtype PubMed ID
esv23132 CNV loss 19812545
nsv564346 CNV loss 21841781

Relevant External Links for NKX2-1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NKX2-1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NKX2-1-AS1 Gene

Disorders for NKX2-1-AS1 Gene

Relevant External Links for NKX2-1-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NKX2-1-AS1

No disorders were found for NKX2-1-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NKX2-1-AS1 Gene

Publications for NKX2-1-AS1 Gene

  1. Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. (PMID: 25307233) Zhao W. … Jiao S. (Sci Rep 2014) 3 64
  2. Genome wide association study of age at menarche in the Japanese population. (PMID: 23667675) Tanikawa C. … Matsuda K. (PLoS ONE 2013) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for NKX2-1-AS1 Gene

Sources for NKX2-1-AS1 Gene

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