NKX2-1-AS1 Gene
RNA gene GIFtS: 18
GCID: GC14P036989
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NKX2-1 Antisense RNA 1(Previous name: NKX2-1 antisense RNA 1 (non-protein coding))
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Aliases
for NKX2-1-AS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
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Subcategory (RNA class): antisense
Quality score for this RNA gene is 3
| Aliases |
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| NKX2-1 Antisense RNA 11 2 | | NKX2-1 Antisense RNA 1 (Non-Protein Coding)1 |
Export aliases for NKX2-1-AS1 gene to outside databases |
Summaries
for NKX2-1-AS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for NKX2-1-AS1 Gene: 
NKX2-1-AS1 (NKX2-1 antisense RNA 1) is an RNA gene, and is affiliated with the antisense RNA class.
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Genomic Views
for NKX2-1-AS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.2 NT_026437.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NKX2-1-AS1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NKX2-1-AS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NKX2-1-AS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 14q13.3 HGNC cytogenetic band: 14q13.3NKX2-1-AS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P036989: view genomic region
(about GC identifiers)
Start:
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36,988,483 bp from pter |
End:
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36,992,221 bp from pter |
Size:
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3,739 bases |
Orientation:
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plus strand |
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Proteins
for NKX2-1-AS1 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for NKX2-1-AS1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| HGNC Gene Families:
LNCRNA: Long non-coding RNAs
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Function
for NKX2-1-AS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
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Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for NKX2-1-AS1 | |  | Search LifeMap BioReagents cell lines for NKX2-1-AS1 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
Pathways & Interactions
for NKX2-1-AS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NKX2-1-AS1
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Drugs & Compounds
for NKX2-1-AS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for NKX2-1-AS1
Search CenterWatch for drugs/clinical trials and news about NKX2-1-AS1
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Transcripts
for NKX2-1-AS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for NKX2-1-AS1: NKX2-1 antisense RNA 1 Hs.497090 [show with all ESTs]Unigene Representative Sequence: XR_1327591 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000521292(uc001wtw.1)
Additional mRNA sequence: BX161496.1 XR_132759.1 XR_172038.1 2 DOTS entries: DT.100749639 DT.97792573
GeneLoc Exon Structure
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Expression
for NKX2-1-AS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for NKX2-1-AS1:none
NKX2-1-AS1 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image
Genevestigator expression for NKX2-1-AS1
SOURCE GeneReport for Unigene cluster: Hs.497090
SABiosciences Custom PCR Arrays for NKX2-1-AS1
Primer
Products: |  | Browse OriGene qPCR
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat NKX2-1-AS1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
Orthologs
for NKX2-1-AS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for NKX2-1-AS1 (if available)
TreeFam Gene Tree for NKX2-1-AS1 (if available) |
Paralogs
for NKX2-1-AS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NKX2-1-AS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for NKX2-1-AS1 (36988483 - 36992221 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for NKX2-1-AS1: --
| | SABiosciences Cancer Mutation PCR Assays |
| | 2 SABiosciences qBiomarker Copy Number PCR Arrays containing NKX2-1-AS1: |
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Disorders
/ Diseases
for NKX2-1-AS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for NKX2-1-AS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for NKX2-1-AS1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NKX2-1-AS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genome wide association study of age at menarche in th e Japanese population. (PubMed id 23667675)1 Tanikawa C....Matsuda K. (2013)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
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External Searches for NKX2-1-AS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing NKX2-1-AS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing NKX2-1-AS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NKX2-1-AS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for NKX2-1-AS1 gene:
Search GeneIP for patents involving NKX2-1-AS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NKX2-1-AS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NKX2-1-AS1 | | | QIAGEN SeqTarget long-range PCR primers for resequencing NKX2-1-AS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NKX2-1-AS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NKX2-1-AS1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NKX2-1-AS1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NKX2-1-AS1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKX2-1-AS1 |
|  |  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NKX2-1-AS1 |
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