Aliases for NKX2-1-AS1 Gene
Subcategory (RNA class) for NKX2-1-AS1 Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for NKX2-1-AS1 Gene
External Ids for NKX2-1-AS1 Gene
- HGNC: 40585
- Entrez Gene: 100506237
- Ensembl: ENSG00000253563
Previous GeneCards Identifiers for NKX2-1-AS1 Gene
- GC14P036989
Summaries for NKX2-1-AS1 Gene
GeneCards Summary for NKX2-1-AS1 Gene
NKX2-1-AS1 (NKX2-1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.
Additional gene information for NKX2-1-AS1 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NKX2-1-AS1 Gene
Genomics for NKX2-1-AS1 Gene
GeneHancer (GH) Regulatory Elements for NKX2-1-AS1 Gene
Promoters and enhancers for NKX2-1-AS1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH14I036517 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE dbSUPER | 550.8 | 0.0 | -45 | 4.2 | ELF3 PKNOX1 INSM2 DMAP1 GLI4 ZNF2 ZNF48 RAD21 RFX5 ZNF335 | ENSG00000257520 NKX2-1 NKX2-1-AS1 PAX9 NKX2-8 SFTA3 ENSG00000283098 | |
| GH14I036676 | Enhancer | 0.7 | Ensembl ENCODE dbSUPER | 10 | +157.1 | 157085 | 0.3 | SP1 | NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 PAX9 ENSG00000258690 | |
| GH14I036281 | Enhancer | 0.6 | ENCODE | 9.9 | -237.8 | -237768 | 0.2 | HCFC1 NFYC SIX5 ELF1 GABPA ETS1 GABPB1 ZNF143 PRDM10 CREM | SFTA3 NKX2-1-AS1 NKX2-1 RPL29P3 NKX2-8 MBIP RN7SKP21 | |
| GH14I036279 | Enhancer | 0.5 | ENCODE | 9.9 | -239.5 | -239504 | 1.1 | POLR2A POU5F1 HMBOX1 NFE2 | SFTA3 NKX2-1 NKX2-1-AS1 RPL29P3 NKX2-8 MBIP RN7SKP21 | |
| GH14I036673 | Enhancer | 0.2 | dbSUPER | 10 | +154.3 | 154259 | 0.3 | NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 PAX9 ENSG00000258690 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for NKX2-1-AS1 Gene
Genomic Locations for NKX2-1-AS1 Gene
- chr14:36,519,278-36,523,016
- (GRCh38/hg38)
- Size:
- 3,739 bases
- Orientation:
- Plus strand
- chr14:36,988,483-36,992,221
- (GRCh37/hg19)
Genomic View for NKX2-1-AS1 Gene
Genes around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q13.3 by Ensembl
- 14q13.3 by Entrez Gene
- 14q13.3 by HGNC
NKX2-1-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NKX2-1-AS1 Gene
Proteins for NKX2-1-AS1 Gene
Post-translational modifications for NKX2-1-AS1 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for NKX2-1-AS1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NKX2-1-AS1
- Origene Custom Protein Services for NKX2-1-AS1
- Search GeneTex for Proteins for NKX2-1-AS1
No data available for DME Specific Peptides for NKX2-1-AS1 Gene
Domains & Families for NKX2-1-AS1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NKX2-1-AS1 Gene
Function for NKX2-1-AS1 Gene
Phenotypes From GWAS Catalog for NKX2-1-AS1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NKX2-1-AS1
-
- Search ViGene Biosciences for NKX2-1-AS1
CRISPR Products
- Browse CRISPR knockouts for NKX2-1-AS1
- Applied Biological Materials CRISPR for NKX2-1-AS1
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Inhibitory RNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Clone Products
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for NKX2-1-AS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NKX2-1-AS1 Gene
Localization for NKX2-1-AS1 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NKX2-1-AS1 Gene
Transcripts for NKX2-1-AS1 Gene
mRNA/cDNA for NKX2-1-AS1 Gene
- (3) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NKX2-1-AS1 Gene
CRISPR Products
- Browse CRISPR knockouts for NKX2-1-AS1
- Applied Biological Materials CRISPR for NKX2-1-AS1
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Inhibitory RNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Clone Products
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for NKX2-1-AS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Relevant External Links for NKX2-1-AS1 Gene
- GeneLoc Exon Structure for
- NKX2-1-AS1
- ECgene alternative splicing isoforms for
- NKX2-1-AS1
Expression for NKX2-1-AS1 Gene
mRNA differential expression in normal tissues according to GTEx for NKX2-1-AS1 Gene
This gene is overexpressed in Thyroid (x33.0) and Lung (x11.2).
SOURCE GeneReport for Unigene cluster for NKX2-1-AS1 Gene:
Hs.497090
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NKX2-1-AS1 Gene
Orthologs for NKX2-1-AS1 Gene
Evolution for NKX2-1-AS1 Gene
- ENSEMBL:
- Gene Tree for NKX2-1-AS1 (if available)
- TreeFam:
- Gene Tree for NKX2-1-AS1 (if available)
No data available for Orthologs for NKX2-1-AS1 Gene
Paralogs for NKX2-1-AS1 Gene
No data available for Paralogs for NKX2-1-AS1 Gene
Variants for NKX2-1-AS1 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs137852692 | pathogenic, Choreoathetosis, hypothyroidism, and neonatal respiratory distress | 36,517,781(+) | C/A | upstream_transcript_variant | |
| rs137852693 | pathogenic, Choreoathetosis, hypothyroidism, and neonatal respiratory distress | 36,517,871(+) | C/A/G | upstream_transcript_variant | |
| rs137852694 | pathogenic, Benign hereditary chorea | 36,517,739(+) | G/A | upstream_transcript_variant | |
| rs147542347 | likely-benign, Benign hereditary chorea, Choreoathetosis, hypothyroidism, and neonatal respiratory distress | 36,517,391(+) | C/A | upstream_transcript_variant | |
| rs201979429 | likely-benign, Benign hereditary chorea, Choreoathetosis, hypothyroidism, and neonatal respiratory distress | 36,520,101(+) | C/A/G/T | intron_variant |
Additional Variant Information for NKX2-1-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NKX2-1-AS1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NKX2-1-AS1 Gene
Disorders for NKX2-1-AS1 Gene
Additional Disease Information for NKX2-1-AS1
No disorders were found for NKX2-1-AS1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NKX2-1-AS1 Gene
Publications for NKX2-1-AS1 Gene
- Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. (PMID: 25307233) Zhao W … Jiao S (Scientific reports 2014) 3 58
- Genome wide association study of age at menarche in the Japanese population. (PMID: 23667675) Tanikawa C … Matsuda K (PloS one 2013) 3 58
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
Products for NKX2-1-AS1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NKX2-1-AS1
- Origene Custom Protein Services for NKX2-1-AS1
- Browse OriGene Inhibitory RNA Products For NKX2-1-AS1
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for NKX2-1-AS1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NKX2-1-AS1
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- GenScript Custom Purified and Recombinant Proteins Services for NKX2-1-AS1
- GenScript Custom Assay Services for NKX2-1-AS1
- GenScript Custom overexpressing Cell Line Services for NKX2-1-AS1
- Browse GenScript CRISPR for NKX2-1-AS1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for NKX2-1-AS1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for NKX2-1-AS1
- Search GeneTex for Proteins for NKX2-1-AS1
Sources for NKX2-1-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew