Aliases for NKX2-1-AS1 Gene
Subcategory (RNA class) for NKX2-1-AS1 Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for NKX2-1-AS1 Gene
External Ids for NKX2-1-AS1 Gene
- HGNC: 40585
- Entrez Gene: 100506237
- Ensembl: ENSG00000253563
Previous GeneCards Identifiers for NKX2-1-AS1 Gene
- GC14P036989
Summaries for NKX2-1-AS1 Gene
GeneCards Summary for NKX2-1-AS1 Gene
NKX2-1-AS1 (NKX2-1 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NKX2-1-AS1 Gene
Genomics for NKX2-1-AS1 Gene
Regulatory Elements for NKX2-1-AS1 Gene
Enhancers for NKX2-1-AS1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH14G036676 | 1.4 | Ensembl ENCODE dbSUPER | 10 | +157.1 | 157086 | 0.3 | ZSCAN4 ZNF493 INSM2 FEZF1 ZNF2 ZNF155 ZEB1 ZNF335 ZNF121 ZNF23 | NKX2-8 RPL29P3 NKX2-1-AS1 NKX2-1 SFTA3 LOC105370455 ENSG00000258690 |
| GH14G036281 | 0.7 | ENCODE | 9.9 | -237.8 | -237769 | 0.2 | ATF1 L3MBTL2 HCFC1 NFYC SIX5 ELF4 MNT ETS1 NFYB GABPB1 | SFTA3 NKX2-1 NKX2-1-AS1 RPL29P3 NKX2-8 MBIP RN7SKP21 |
| GH14G036673 | 0.6 | dbSUPER | 10 | +154.3 | 154260 | 0.3 | RFX1 PKNOX1 SIN3A REST MNT ZNF335 PRDM6 CTBP1 FOS | NKX2-8 RPL29P3 NKX2-1 NKX2-1-AS1 SFTA3 LOC105370455 ENSG00000258690 |
| GH14G036279 | 0.6 | ENCODE | 9.9 | -239.5 | -239505 | 1.1 | PKNOX1 CHD1 CHD7 EP300 GATA3 CTBP1 POU5F1 HMBOX1 NFE2 | SFTA3 NKX2-1 NKX2-1-AS1 RPL29P3 NKX2-8 MBIP RN7SKP21 |
| GH14G036517 | 1.4 | Ensembl ENCODE dbSUPER | 0.7 | 0.0 | -45 | 4.2 | PKNOX1 DMAP1 GLI4 ZNF2 ZNF48 GLIS2 ZNF143 FOS SP3 CBX8 | PAX9 NKX2-8 NKX2-1-AS1 SFTA3 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for NKX2-1-AS1 Gene
- Chromosome:
- 14
- Start:
- 36,519,278 bp from pter
- End:
- 36,523,016 bp from pter
- Size:
- 3,739 bases
- Orientation:
- Plus strand
Genomic View for NKX2-1-AS1 Gene
Genes around NKX2-1-AS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q13.3 by Ensembl
- 14q13.3 by Entrez Gene
- 14q13.3 by HGNC
NKX2-1-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NKX2-1-AS1 Gene
Proteins for NKX2-1-AS1 Gene
Post-translational modifications for NKX2-1-AS1 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for NKX2-1-AS1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NKX2-1-AS1
- Origene Custom Protein Services for NKX2-1-AS1
- Search GeneTex for Proteins for NKX2-1-AS1
No data available for DME Specific Peptides for NKX2-1-AS1 Gene
Domains & Families for NKX2-1-AS1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NKX2-1-AS1 Gene
Function for NKX2-1-AS1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NKX2-1-AS1
-
- Search ViGene Biosciences for NKX2-1-AS1
CRISPR Products
- Browse CRISPR knockouts for NKX2-1-AS1
miRNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Inhibitory RNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Clone Products
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NKX2-1-AS1 Gene
Localization for NKX2-1-AS1 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NKX2-1-AS1 Gene
Transcripts for NKX2-1-AS1 Gene
mRNA/cDNA for NKX2-1-AS1 Gene
- (3) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NKX2-1-AS1 Gene
CRISPR Products
- Browse CRISPR knockouts for NKX2-1-AS1
miRNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Inhibitory RNA Products
- Search ViGene Biosciences for NKX2-1-AS1
Clone Products
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Relevant External Links for NKX2-1-AS1 Gene
- GeneLoc Exon Structure for
- NKX2-1-AS1
- ECgene alternative splicing isoforms for
- NKX2-1-AS1
Expression for NKX2-1-AS1 Gene
mRNA differential expression in normal tissues according to GTEx for NKX2-1-AS1 Gene
This gene is overexpressed in Thyroid (x33.0) and Lung (x11.2).
SOURCE GeneReport for Unigene cluster for NKX2-1-AS1 Gene:
Hs.497090
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NKX2-1-AS1 Gene
Orthologs for NKX2-1-AS1 Gene
Evolution for NKX2-1-AS1 Gene
- ENSEMBL:
- Gene Tree for NKX2-1-AS1 (if available)
- TreeFam:
- Gene Tree for NKX2-1-AS1 (if available)
No data available for Orthologs for NKX2-1-AS1 Gene
Paralogs for NKX2-1-AS1 Gene
No data available for Paralogs for NKX2-1-AS1 Gene
Variants for NKX2-1-AS1 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs137852692 | Pathogenic | 36,517,781(-) | CGCAG(G/T)TCAAG | upstream-variant-2KB, reference, missense | |
| rs137852693 | Pathogenic | 36,517,871(-) | TGTAC(C/G/T)AGCTG | upstream-variant-2KB, reference, missense, stop-gained | |
| rs137852694 | Pathogenic | 36,517,739(-) | AGCGC(C/T)AGGCC | upstream-variant-2KB, reference, stop-gained | |
| rs28936671 | Pathogenic | 36,517,757(-) | ACCAC(A/C)GCTAC | upstream-variant-2KB, reference, missense | |
| rs28936672 | Pathogenic | 36,517,771(-) | GATCT(G/T)GTTCC | upstream-variant-2KB, reference, missense |
Relevant External Links for NKX2-1-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NKX2-1-AS1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NKX2-1-AS1 Gene
Disorders for NKX2-1-AS1 Gene
Relevant External Links for NKX2-1-AS1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- NKX2-1-AS1
No disorders were found for NKX2-1-AS1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NKX2-1-AS1 Gene
Publications for NKX2-1-AS1 Gene
- Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. (PMID: 25307233) Zhao W. … Jiao S. (Sci Rep 2014) 3 64
- Genome wide association study of age at menarche in the Japanese population. (PMID: 23667675) Tanikawa C. … Matsuda K. (PLoS ONE 2013) 3 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
Products for NKX2-1-AS1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NKX2-1-AS1
- Origene Custom Protein Services for NKX2-1-AS1
- Browse OriGene Inhibitory RNA Products For NKX2-1-AS1
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for NKX2-1-AS1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NKX2-1-AS1
- GenScript: Custom all cDNA clones Services for NKX2-1-AS1
- GenScript Custom Purified and Recombinant Proteins Services for NKX2-1-AS1
- GenScript Custom Assay Services for NKX2-1-AS1
- GenScript Custom overexpressing Cell Line Services for NKX2-1-AS1
- Browse GenScript CRISPR for NKX2-1-AS1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for NKX2-1-AS1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search GeneTex for Antibodies for NKX2-1-AS1
- Search GeneTex for Proteins for NKX2-1-AS1
- Search ViGene Biosciences for NKX2-1-AS1
- Cyagen custom Knockout/knockin (KOKI) mouse models for NKX2-1-AS1
- VectorBuilder custom plasmid, inducible vectors for NKX2-1-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NKX2-1-AS1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for NKX2-1-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer